Medicine and Health Sciences Commons^™

A Roadmap To Reopening A Neurosurgical Practice In The Age Of Covid-19, Rs D'Amico, G Baum, Y Serulle, D Silva, Ml Smith, Ra Wallack, Ja Ellis, M Levine, R Oritz, Ja Boockvar, Dj Langer

Journal Articles

No abstract provided.

Clinical Evaluation Of Three Sample-To-Answer Platforms For The Detection Of Sars-Cov-2, W Zhen, E Smith, R Manji, D Schron, Gj Berry

Journal Articles

No abstract provided.

Comparison Of Four Molecular In Vitro Diagnostic Assays For The Detection Of Sars-Cov-2 In Nasopharyngeal Specimens., W Zhen, R Manji, E Smith, Gj Berry

Journal Articles

No abstract provided.

Pretreatment Nutritional Status And Response To Checkpoint Inhibitors In Lung Cancer., C. Lee, C. E. Devoe, X. Zhu, J. S. Fishbein, N. Seetharamu

Journal Articles

Background:Checkpoint inhibitors are integral to non-small-cell lung cancer treatment. Existing data suggests that nutritional status may play a role in antitumor immunity. Materials & methods:This retrospective study of 106 non-small-cell lung cancer patients who started checkpoint inhibitors between 2014 and 2017 at our institution assessed relationship of nutritional parameters to overall survival (OS) and progression-free survival. Results:Mean age was 68.7 ± 9.2 years and 59.4% patients were male. On multivariate analysis for OS, hypoalbuminemia and significant weight loss were prognostic at p-values of 0.0005 and 0.0052, respectively. We noted a parabolic association between age and OS (p = 0.026, 0.0025). …

Management Of Upper Gi Bleeding In Patients With Covid-19 Pneumonia, K. Cavaliere, C. Levine, P. Wander, D. V. Sejpal, A. J. Trindade

Journal Articles

No abstract provided.

Polycystic Liver With Cardiac Compression Leading To Atrial Fibrillation: Case Report And Review Of The Literature., A. Elfiky, C. T. El Imad, B. Karam, S. M. Mulrooney

Journal Articles

Polycystic liver disease (PCLD) is a rare condition that most often occurs in patients with polycystic kidney disease and less commonly as an isolated liver disease. Complications include cyst rupture, infection, hemorrhage, and compression of surrounding organs by large cysts. We present the case of a patient with a history of PCLD who presented to our hospital with palpitations and was found to have atrial fibrillation. Imaging and echocardiograph revealed a dominant large cyst compressing the right atrium. Other etiologies including thyroid disease, ischemic heart disease, and electrolytes abnormalities were excluded. The patient refused surgical intervention and was conservatively treated …

Eikenella Corrodens And Streptococcus Anginosus Co-Infection Causing Skull Base Osteomyelitis And Internal Carotid Artery Lesion, K. Patel, C. Park, Z. Memon, N. Ilyas

Journal Articles

© 2020 The Author(s) A 35-year-old male presented with headaches and fevers. MRI of his head showed skull-based infection of the clivus extended to the right internal carotid artery. Blood and sinus cultures were positive for Eikenella corrodens and Streptococcus anginosus. He had intravenous antibiotics and sinus washout. The patient had full neurological recovery following this.

Over-The-Scope Clip To The Rescue! A Novel Tool For Refractory Acute Nonvariceal Upper Gastrointestinal Hemorrhage, S. Amarnath, H. Khan, J. Philipose, J. Abergel

Journal Articles

© 2020 © 2020 The Author(s). Published by S. Karger AG, Basel. Nonvariceal upper gastrointestinal hemorrhage (NVUGIH) is more prevalent than lower gastrointestinal hemorrhage and carries a high risk of mortality in the elderly, especially those with significant cardiovascular comorbidities. Traditional endoscopic methods, such as through-the-scope clips, electrocautery, and epinephrine injection, are frequently used to control these bleeds; however, they carry a 10% risk of rebleeding, and this itself carries a mortality risk of 36%. The larger over-the-scope clips (OTSC) that were initially used for the closure of fistulas and perforations are now gradually being implemented to manage NVUGIH. To …

The Effect Of Chloroquine, Hydroxychloroquine And Azithromycin On The Corrected Qt Interval In Patients With Sars-Cov-2 Infection, M. Saleh, J. Gabriels, D. Chang, B. S. Kim, A. Mansoor, E. Mahmood, P. Makker, H. Ismail, B. Goldner, J. Willner, S. Beldner, R. Mitra, R. John, J. Chinitz, N. Skipitaris, S. Mountantonakis, L. M. Epstein

Journal Articles

Background - The novel SARs-CoV-2 coronavirus is responsible for the global COVID-19 pandemic. Small studies have shown a potential benefit of chloroquine/hydroxychloroquine ± azithromycin for the treatment of COVID-19. Use of these medications alone, or in combination, can lead to a prolongation of the QT interval, possibly increasing the risk of Torsade de pointes (TdP) and sudden cardiac death. Methods - Hospitalized patients treated with chloroquine/hydroxychloroquine ± azithromycin from March 1st through the 23rd at three hospitals within the Northwell Health system were included in this prospective, observational study. Serial assessments of the QT interval were performed. The primary outcome …

Impact Of The Covid-19 Pandemic On Interventional Cardiology Fellowship Training In The New York Metropolitan Area: A Perspective From The United States Epicenter, T. Gupta, T. M. Nazif, T. P. Vahl, H. Ahmad, A. E. Bortnick, R. Jauhar, R. Kandov, M. Kim, A. Lee, S. Kodali, +11 Additional Authors

Journal Articles

© 2020 Wiley Periodicals, Inc. Background: The healthcare burden posed by the coronavirus disease 2019 (COVID-19) pandemic in the New York Metropolitan area has necessitated the postponement of elective procedures resulting in a marked reduction in cardiac catheterization laboratory (CCL) volumes with a potential to impact interventional cardiology (IC) fellowship training. Methods: We conducted a web-based survey sent electronically to 21 Accreditation Council for Graduate Medical Education accredited IC fellowship program directors (PDs) and their respective fellows. Results: Fourteen programs (67%) responded to the survey and all acknowledged a significant decrease in CCL procedural volumes. More than half of the …

Management Of Acute Myocardial Infarction During The Covid-19 Pandemic., E. Mahmud, H. L. Dauerman, F. G. Welt, J. C. Messenger, S. V. Rao, C. Grines, A. Mattu, R. Jauhar, P. Meraj, T. D. Henry, +3 Additional Authors

Journal Articles

The worldwide pandemic caused by the novel acute respiratory syndrome coronavirus 2 (SARS-CoV2) has resulted in a new and lethal disease termed coronavirus disease 2019 (COVID-19). Although there is an association between cardiovascular disease and COVID-19, the majority of patients who need cardiovascular care for the management of ischemic heart disease may not be infected with COVID-19. The objective of this document is to provide recommendations for a systematic approach for the care of patients with an acute myocardial infarction (AMI) during the COVID-19 pandemic. There is a recognition of two major challenges in providing recommendations for AMI care in …

Covid-19 Infection Unmasking Brugada Syndrome, D. Chang, M. Saleh, Y. Garcia-Bengo, E. Choi, L. Epstein, J. Willner

Journal Articles

No abstract provided.

Feasibility Of Radiofrequency Catheter Ablation In A Patient With Deep Brain Stimulators, M. Grabie, J. Gabriels, K. Xiang, C. S. Elayi, J. N. Makaryus, J. N. Catanzaro

Journal Articles

No abstract provided.

Author's Reply—Is It Really Covid-19?, D. Chang, L. M. Epstein

Journal Articles

No abstract provided.

The Covid-19 Pandemic And Acute Aortic Dissections In New York: A Matter Of Public Health., I. El-Hamamsy, D. R. Brinster, J. J. Derose, L. N. Girardi, K. Hisamoto, M. N. Imam, S. Itagaki, P. A. Kurlansky, C. Lau, H. Takayama, +3 Additional Authors

Journal Articles

No abstract provided.

A Comparison Of Existing Risk Prediction Models In Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation, B. Worku, M. Gaudino, D. Avgerinos, K. Ramasubbu, I. Gambardella, I. Gulkarov, S. Khin

Journal Articles

© 2020 The Author(s) Background: Patients undergoing consideration for venoarterial extracorporeal membrane oxygenation (VA-ECMO) require an immediate risk profile assessment in the setting of incomplete information. A number of survival prediction models for critically ill patients and patients undergoing elective cardiac surgery or institution of VA-ECMO support have been designed. We assess the ability of these models to predict outcomes in a cohort of patients undergoing institution of VA-ECMO for cardiogenic shock or cardiac arrest. Methods: Fifty-one patients undergoing institution of VA-ECMO support were retrospectively analyzed. APACHE II, SOFA, SAPS II, Encourage, SAVE, and ACEF scores were calculated. Their ability …

Multifocal Extracranial Mycotic Aneurysms In A Patient With Endocarditis, A. M. Spring, M. A. Catalano, B. F. Farber, K. V. Krishnasastry, P. J. Yu

Journal Articles

© 2020 This report describes the case of a 44-year-old man with Streptococcus gallolyticus (formerly S. bovis) endocarditis requiring surgical mitral valve replacement who developed multifocal extracranial mycotic aneurysms after the resolution of infection.

Management Of Elective Aortic Valve Replacement Over The Long Term In The Era Of Covid-19, C. Basman, C. A. Kliger, L. Pirelli, S. J. Scheinerman

Journal Articles

No abstract provided.

Potential Impacts Of A Novel Integrated Extracorporeal-Cpr Workflow Using An Interventional Radiology And Immediate Whole-Body Computed Tomography System In The Emergency Department, K. Hayashida, T. Kinoshita, K. Yamakawa, S. J. Miyara, L. B. Becker, S. Fujimi

Journal Articles

Extracorporeal cardiopulmonary resuscitation (ECPR) can be associated with increased survival and neurologic benefits in selected patients with out-of-hospital cardiac arrest (OHCA). However, there remains insufficient evidence to recommend the routine use of ECPR for patients with OHCA. A novel integrated trauma workflow concept that utilizes a sliding computed tomography (CT) scanner and interventional radiology (IR) system, named a hybrid emergency room system (HERS), allowing emergency therapeutic interventions and CT examination without relocating trauma patients, has recently evolved in Japan. HERS can drastically shorten the ECPR implementation time and more quickly facilitate definitive interventions than the conventional advanced cardiovascular life support …

Mechanical, Team-Focused, Video-Reviewed Cardiopulmonary Resuscitation Improves Return Of Spontaneous Circulation After Emergency Department Implementation, D. M. Rolston, T. Li, C. Owens, G. Haddad, T. J. Palmieri, V. Blinder, J. L. Wolff, M. Cassara, Q. Zhou, L. B. Becker

Journal Articles

No abstract provided.

Idiopathic Bilateral Internal Jugular Vein Thrombosis Diagnosed By Point-Of-Care Ultrasound., V. M. Aquino-Jose, J. Johnson, T. Dulani

Journal Articles

Internal jugular vein (IJV) thrombosis is an unusual condition, especially when it develops bilaterally. This is a case of bilateral IJV thrombosis in a 77-year old female who presented to the emergency department with neck and arm swelling after discontinuing apixaban and undergoing an oropharyngeal procedure. The diagnosis of bilateral IJV thrombosis was made with the use of point-of-care ultrasound to evaluate bilateral jugular vein distention and bilateral upper extremity pitting edema found on her physical examination.

A Telehealth-Delivered Pulmonary Rehabilitation Intervention In Underserved Hispanic And African American Patients With Chronic Obstructive Pulmonary Disease: A Community-Based Participatory Research Approach., R. Pekmezaris, A. Kozikowski, B. Pascarelli, G. Wolf-Klein, E. Boye-Codjoe, S. Jacome, D. Madera, D. Tsang, J. Polo, N. Hajizadeh, +3 Additional Authors

Journal Articles

BACKGROUND:Although home telemonitoring (TM) is a promising approach for patients managing their chronic disease, rehabilitation using home TM has not been tested for use with individuals living with chronic obstructive pulmonary disease (COPD) residing in underserved communities. OBJECTIVE:This study aimed to analyze qualitative data from focus groups with key stakeholders to ensure the acceptability and usability of the TM COPD intervention. METHODS:We utilized a community-based participatory research (CBPR) approach to adapt a home TM COPD intervention to facilitate acceptability and feasibility in low-income African American and Hispanic patients. The study engaged community stakeholders in the process of modifying the intervention …

Prognostic Factors For Vte And Bleeding In Hospitalized Medical Patients: A Systematic Review And Meta-Analysis, A. J. Darzi, S. G. Karam, R. Charide, I. Etxeandia-Ikobaltzeta, M. Cushman, M. K. Gould, L. Mbuagbaw, F. A. Spencer, A. C. Spyropoulos, H. J. Schunemann, +9 Additional Authors

Journal Articles

No abstract provided.

Covid-19 Presenting As Stroke, A. Avula, K. Nalleballe, N. Narula, S. Sapozhnikov, V. Dandu, S. Toom, A. Glaser, D. Elsayegh

Journal Articles

© 2020 Elsevier Inc. Objective: Acute stroke remains a medical emergency even during the COVID-19 pandemic. Most patients with COVID-19 infection present with constitutional and respiratory symptoms; while others present with atypical gastrointestinal, cardiovascular, or neurological manifestations. Here we present a series of four patients with COVID-19 that presented with acute stroke. Methods: We searched the hospital databases for patients that presented with acute stroke and concomitant features of suspected COVID-19 infection. All patients who had radiographic evidence of stroke and PCR-confirmed COVID-19 infection were included in the study. Patients admitted to the hospital with PCR- confirmed COVID-19 disease whose …

Arterial Thromboembolic Complications In Covid-19 In Low-Risk Patients Despite Prophylaxis, D. O. Griffin, A. Jensen, M. Khan, J. Chin, K. Chin, R. Parnell, C. Awwad, D. Patel

Journal Articles

No abstract provided.

Cytokine Secretion In Breast Cancer Cells – Milliplex Assay Data, K. Chen, L. Satlof, G. Stoffels, U. Kothapalli, N. Ziluck, M. Lema, L. Poretsky, D. Avtanski

Journal Articles

© 2019 The Author(s) Metastatic breast cancer is the most advanced stage of breast cancer and the leading cause of breast cancer mortality. Although understanding of the cancer progression and metastasis process has improved, the bi-directional communication between the tumor cell and the tumor microenvironment is still not well understood. Breast cancer cells are highly secretory, and their secretory activity is modulated by a variety of inflammatory stimuli present in the tumor microenvironment. Here, we characterized the cytokine expression in human breast cancer cells (MDA-MB-231, MCF-7, T-47D, and BT-474) in vitro using 41 cytokine MILLIPLEX assay. Further, we compared cytokine …

Covid-19 In Kidney Transplant Recipients, V. Nair, N. Jandovitz, J. S. Hirsch, G. Nair, M. Abate, M. Bhaskaran, E. Grodstein, I. Berlinrut, D. Hirschwerk, S. L. Cohen, K. W. Davidson, A. J. Dominello, G. A. Osorio, S. Richardson, L. W. Teperman, E. P. Molmenti

Journal Articles

No abstract provided.

The Implementation And Sustainment Facilitation Strategy Improved Implementation Effectiveness And Intervention Effectiveness: Results From A Cluster-Randomized, Type 2 Hybrid Trial, Bryan R. Garner, Heather J. Gotham, Michael Chaple, Steve Martino, James H. Ford Ii, Mathew R. Roosa, Kathryn Joan Speck, Denna Vandersloot, Michael Bradshaw, Elizabeth L. Ball, Alyssa K. Toro, Christopher Griggs, Stephen J. Tueller

University of Nebraska Public Policy Center: Publications

Background: Substance use disorders (SUDs) among people with HIV are both prevalent and problematic. The Substance Abuse Treatment to HIV care project was funded to test the Implementation and Sustainment Facilitation (ISF) strategy as an adjunct to the Addiction Technology Transfer Center (ATTC) strategy for integrating a motivational interviewing-based brief intervention (MIBI) for SUDs within HIV community-based organizations. Methods: Using a cluster-randomized, type 2 hybrid trial design, 39 HIV organizations were randomized to either (1) ATTC (n = 19) or (2) ATTC + ISF (n = 20). Each HIV organization identified two staff members to be prepared to implement the …

Selecting A Journal For Your Manuscript: A 4-Step Process, Claire Olivia Sharifi, Robin Buccheri

Gleeson Library Faculty and Staff Research and Scholarship

Background Identifying the most appropriate journal for a manuscript can be challenging for both experienced and novice nurse authors. Several factors should be considered when selecting a journal (e.g., peer-reviewed, target audience, type of manuscripts accepted, type of copyright and publishing model used). Selecting the most appropriate journal can save time for both authors and publishers.

Purpose The purpose of this article is to provide nurses, particularly those new to scholarly publishing, with clear, plain language guidance on the processes and considerations involved in selecting a journal for publication.

Methods A librarian and a nurse educator collaborated to develop an …

Determining The Advantageous Acute Migraine Treatment: Rimegepant And Lasmiditan Review Of Literature, Tiffany A. Johnson

Honors Undergraduate Theses

This research aims to evaluate two new pharmaceuticals on the market. Rimegepant and Lasmiditan target the trigeminovascular system and respectively, are characterized in the gepant and ditan classes of pharmaceuticals. Based on a review of studies, Rimegepant was determined to be the advantageous acute treatment. This is not conclusive due to inequivalent comparison in sample size and amount of research completed. It is encouraged for additional research to be imposed before a conclusive determination of the advantageous acute treatment can be distinguished.