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Articles 154501 - 154530 of 325777
Full-Text Articles in Medicine and Health Sciences
Letter: A Guide To The Prioritization Of Neurosurgical Cases After The Covid-19 Pandemic., Jg Thomas, S Gandhi, Tg White, C Jocelyn, Tm Soo, M Eisenberg, M Schulder, Rk Narayan
Letter: A Guide To The Prioritization Of Neurosurgical Cases After The Covid-19 Pandemic., Jg Thomas, S Gandhi, Tg White, C Jocelyn, Tm Soo, M Eisenberg, M Schulder, Rk Narayan
Journal Articles
No abstract provided.
Maternal Mortality Among Women With Covid-19 Admitted To The Intensive Care Unit., Mj Blitz, B Rochelson, N Meirowitz, L Prasannan, Tj Rafael, S Chakravarthy, La Bracero, Sw Wasden, Sl Pachtmanshetty, O Santandreu, Fa Chervenak, Bm Schwartz, M Nimaroff, +2 Additional Authors
Maternal Mortality Among Women With Covid-19 Admitted To The Intensive Care Unit., Mj Blitz, B Rochelson, N Meirowitz, L Prasannan, Tj Rafael, S Chakravarthy, La Bracero, Sw Wasden, Sl Pachtmanshetty, O Santandreu, Fa Chervenak, Bm Schwartz, M Nimaroff, +2 Additional Authors
Journal Articles
No abstract provided.
Thrombotic Microangiopathy In A Patient With Covid-19., Kd Jhaveri, Lr Meir, Bs Flores Chang, R Parikh, R Wanchoo, Ml Barilla-Labarca, V Bijol, N Hajizadeh
Thrombotic Microangiopathy In A Patient With Covid-19., Kd Jhaveri, Lr Meir, Bs Flores Chang, R Parikh, R Wanchoo, Ml Barilla-Labarca, V Bijol, N Hajizadeh
Journal Articles
No abstract provided.
Clinically Significant Anticardiolipin Antibodies Associated With Covid-19, S Hossri, M Shadi, Z Hamarsha, R Schneider, D El-Sayegh
Clinically Significant Anticardiolipin Antibodies Associated With Covid-19, S Hossri, M Shadi, Z Hamarsha, R Schneider, D El-Sayegh
Journal Articles
No abstract provided.
Coronavirus Disease 2019 (Covid-19) Pandemic Shifts Inpatient Imaging Utilization., Jj Naidich, A Boltyenkov, Jj Wang, J Chusid, D Hughes, Pc Sanelli
Coronavirus Disease 2019 (Covid-19) Pandemic Shifts Inpatient Imaging Utilization., Jj Naidich, A Boltyenkov, Jj Wang, J Chusid, D Hughes, Pc Sanelli
Journal Articles
No abstract provided.
Effect Of Chloroquine, Hydroxychloroquine, And Azithromycin On The Corrected Qt Interval In Patients With Sars-Cov-2 Infection, M Saleh, J Gabriels, D Chang, Bs Kim, A Mansoor, E Mahmood, P Makker, H Ismail, B Goldner, J Willner, S Beldner, R Mitra, R John, J Chinitz, N Skipitaris, S Mountantonakis, Lm Epstein
Effect Of Chloroquine, Hydroxychloroquine, And Azithromycin On The Corrected Qt Interval In Patients With Sars-Cov-2 Infection, M Saleh, J Gabriels, D Chang, Bs Kim, A Mansoor, E Mahmood, P Makker, H Ismail, B Goldner, J Willner, S Beldner, R Mitra, R John, J Chinitz, N Skipitaris, S Mountantonakis, Lm Epstein
Journal Articles
No abstract provided.
Elective Endotracheal Intubation For Urgent Gastrointestinal Endoscopy Among Hospitalized Patients With Sars-Cov-2, P Wander, De Hogan, S Inamdar, Pc Benias, F Haddad, S Andrawes, De Bernstein, D V. Sejpal, A J. Trindade
Elective Endotracheal Intubation For Urgent Gastrointestinal Endoscopy Among Hospitalized Patients With Sars-Cov-2, P Wander, De Hogan, S Inamdar, Pc Benias, F Haddad, S Andrawes, De Bernstein, D V. Sejpal, A J. Trindade
Journal Articles
No abstract provided.
Hypermetabolism And Coronavirus Disease 2019, Pj Yu, H Cassiere, S Derosa, K Bocchieri, S Yar, A Hartman
Hypermetabolism And Coronavirus Disease 2019, Pj Yu, H Cassiere, S Derosa, K Bocchieri, S Yar, A Hartman
Journal Articles
No abstract provided.
Intensive Care Unit Admissions For Pregnant And Nonpregnant Women With Coronavirus Disease 2019, M J. Blitz, A Grünebaum, A Tekbali, E Bornstein, B Rochelson, M Nimaroff, Fa Chervenak
Intensive Care Unit Admissions For Pregnant And Nonpregnant Women With Coronavirus Disease 2019, M J. Blitz, A Grünebaum, A Tekbali, E Bornstein, B Rochelson, M Nimaroff, Fa Chervenak
Journal Articles
No abstract provided.
Limiting Hospital Resources For Acute Appendicitis In Children: Lessons Learned From The U.S. Epicenter Of The Covid-19 Pandemic, Cl Kvasnovsky, Y Shi, B S. Rich, R D. Glick, S Z. Soffer, A M. Lipskar, S Dolgin, A Hong, J M. Prince, C Sathya, +2 Additional Authors
Limiting Hospital Resources For Acute Appendicitis In Children: Lessons Learned From The U.S. Epicenter Of The Covid-19 Pandemic, Cl Kvasnovsky, Y Shi, B S. Rich, R D. Glick, S Z. Soffer, A M. Lipskar, S Dolgin, A Hong, J M. Prince, C Sathya, +2 Additional Authors
Journal Articles
No abstract provided.
Maternal Mortality Among Women With Coronavirus Disease 2019 Admitted To The Intensive Care Unit, Mj Blitz, B Rochelson, H Minkoff, N Meirowitz, L Prasannan, V London, Tj Rafael, S Chakravarthy, La Bracero, Sw Wasden, Sl Pachtman Shetty, O Santandreu, Fa Chervenak, Bm Schwartz, M Nimaroff
Maternal Mortality Among Women With Coronavirus Disease 2019 Admitted To The Intensive Care Unit, Mj Blitz, B Rochelson, H Minkoff, N Meirowitz, L Prasannan, V London, Tj Rafael, S Chakravarthy, La Bracero, Sw Wasden, Sl Pachtman Shetty, O Santandreu, Fa Chervenak, Bm Schwartz, M Nimaroff
Journal Articles
No abstract provided.
Negative Sars-Cov-2 Antibody Testing Following Covid-19 Infection In Two Ms Patients Treated With Ocrelizumab, Jr Thornton, A Harel
Negative Sars-Cov-2 Antibody Testing Following Covid-19 Infection In Two Ms Patients Treated With Ocrelizumab, Jr Thornton, A Harel
Journal Articles
No abstract provided.
Coronavirus Neurosurgical/Head And Neck Drape To Prevent Aerosolization Of Coronavirus Disease 2019 (Covid-19): The Lenox Hill Hospital/Northwell Health Solution, Rs D'Amico, D Khatri, K Kwan, G Baum, Y Serulle, D Silva, Ml Smith, Ja Ellis, M Levine, R Ortiz, Dj Langer, Ja Boockvar
Coronavirus Neurosurgical/Head And Neck Drape To Prevent Aerosolization Of Coronavirus Disease 2019 (Covid-19): The Lenox Hill Hospital/Northwell Health Solution, Rs D'Amico, D Khatri, K Kwan, G Baum, Y Serulle, D Silva, Ml Smith, Ja Ellis, M Levine, R Ortiz, Dj Langer, Ja Boockvar
Journal Articles
No abstract provided.
North American Covid-19 St-Segment-Elevation Myocardial Infarction (Nacmi) Registry: Rationale, Design, And Implications: Rationale And Design Of Nacmi Registry, P Dehghani, Lj Davidson, Cl Grines, K Nayak, J Saw, P Kaul, A Bagai, R Garberich, P Meraj, Td Henry, +9 Additional Authors
North American Covid-19 St-Segment-Elevation Myocardial Infarction (Nacmi) Registry: Rationale, Design, And Implications: Rationale And Design Of Nacmi Registry, P Dehghani, Lj Davidson, Cl Grines, K Nayak, J Saw, P Kaul, A Bagai, R Garberich, P Meraj, Td Henry, +9 Additional Authors
Journal Articles
No abstract provided.
Powerless In The Icu: Perspectives From Icus In The Face Of Covid-19., P Ramachandran, L Swamy, V Kaul, A Agrawal, M Narasimhan
Powerless In The Icu: Perspectives From Icus In The Face Of Covid-19., P Ramachandran, L Swamy, V Kaul, A Agrawal, M Narasimhan
Journal Articles
No abstract provided.
The Underrecognized Prothrombotic Vascular Disease Of Covid-19., Kp Cohoon, G Mahé, Ac Spyropoulos
The Underrecognized Prothrombotic Vascular Disease Of Covid-19., Kp Cohoon, G Mahé, Ac Spyropoulos
Journal Articles
No abstract provided.
Iglv3-21∗01 Is An Inherited Risk Factor For Cll Through The Acquisition Of A Single-Point Mutation Enabling Autonomous Bcr Signaling, P. C. Maity, M. Bilal, M. T. Koning, M. Young, C. A. Van Bergen, V. Renna, A. Nicolò, A. N. Mazzarello, N. Chiorazzi, H. Jumaa, +28 Additional Authors
Iglv3-21∗01 Is An Inherited Risk Factor For Cll Through The Acquisition Of A Single-Point Mutation Enabling Autonomous Bcr Signaling, P. C. Maity, M. Bilal, M. T. Koning, M. Young, C. A. Van Bergen, V. Renna, A. Nicolò, A. N. Mazzarello, N. Chiorazzi, H. Jumaa, +28 Additional Authors
Journal Articles
© 2020 National Academy of Sciences. All rights reserved. The prognosis of chronic lymphocytic leukemia (CLL) depends on different markers, including cytogenetic aberrations, oncogenic mutations, and mutational status of the immunoglobulin (Ig) heavy-chain variable (IGHV) gene. The number of IGHV mutations distinguishes mutated (M) CLL with a markedly superior prognosis from unmutated (UM) CLL cases. In addition, B cell antigen receptor (BCR) stereotypes as defined by IGHV usage and complementaritydetermining regions (CDRs) classify ∼30% of CLL cases into prognostically important subsets. Subset 2 expresses a BCR with the combination of IGHV3-21-derived heavy chains (HCs) with IGLV3- 21-derived light chains (LCs), …
Integrated Urine Proteomics And Renal Single-Cell Genomics Identify An Interferon-Γ Response Gradient In Lupus Nephritis., A. Fava, J. P. Buyon, C. Mohan, T. Zhang, H. M. Belmont, P. Izmirly, A. Arazi, A. Davidson, B. Diamond, M. Petri, +12 Additional Authors
Integrated Urine Proteomics And Renal Single-Cell Genomics Identify An Interferon-Γ Response Gradient In Lupus Nephritis., A. Fava, J. P. Buyon, C. Mohan, T. Zhang, H. M. Belmont, P. Izmirly, A. Arazi, A. Davidson, B. Diamond, M. Petri, +12 Additional Authors
Journal Articles
Lupus nephritis, one of the most serious manifestations of systemic lupus erythematosus (SLE), has both a heterogeneous clinical and pathological presentation. For example, proliferative nephritis identifies a more aggressive disease class that requires immunosuppression. However, the current classification system relies on the static appearance of histopathological morphology which does not capture differences in the inflammatory response. Therefore, a biomarker grounded in the disease biology is needed to understand the molecular heterogeneity of lupus nephritis and identify immunologic mechanism and pathways. Here, we analyzed the patterns of 1000 urine protein biomarkers in 30 patients with active lupus nephritis. We found that …
Eda2r Mediates Podocyte Injury In High Glucose Milieu, X. Lan, V. Kumar, A. Jha, R. Aslam, H. Wang, K. Chen, Y. Yu, W. He, A. Malhotra, P. C. Singhal, +2 Additional Authors
Eda2r Mediates Podocyte Injury In High Glucose Milieu, X. Lan, V. Kumar, A. Jha, R. Aslam, H. Wang, K. Chen, Y. Yu, W. He, A. Malhotra, P. C. Singhal, +2 Additional Authors
Journal Articles
© 2020 Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM) EDA2R is a member of the large family of tumor necrosis factor receptor (TNFR). Previous studies suggested that EDA2R expression might be increased in the kidneys of diabetic mice. However, its mRNA and protein expression in kidneys were not analyzed; moreover, its role in the development of diabetic kidney disease was not explored. Here we analyzed the mRNA and protein expressions of EDA2R in diabetic kidneys and examined its role in the podocyte injury in high glucose milieu. By analysis with real-time PCR, Western blotting, we found …
Steroid Resistance In Diamond Blackfan Anemia Associates With P57(Kip2) Dysregulation In Erythroid Progenitors, R. J. Ashley, H. Yan, N. Wang, J. Hale, B. M. Dulmovits, J. Papoin, M. E. Olive, A. Vlachos, J. M. Lipton, L. Blanc, +8 Additional Authors
Steroid Resistance In Diamond Blackfan Anemia Associates With P57(Kip2) Dysregulation In Erythroid Progenitors, R. J. Ashley, H. Yan, N. Wang, J. Hale, B. M. Dulmovits, J. Papoin, M. E. Olive, A. Vlachos, J. M. Lipton, L. Blanc, +8 Additional Authors
Journal Articles
No abstract provided.
Correcting Smad1/5/8, Mtor, And Vegfr2 Treats Pathology In Hereditary Hemorrhagic Telangiectasia Models, S. Ruiz, H. Zhao, P. Chandakkar, J. Papoin, P. K. Chatterjee, Y. Al-Abed, P. Wang, C. N. Metz, L. Blanc, P. Marambaud, +8 Additional Authors
Correcting Smad1/5/8, Mtor, And Vegfr2 Treats Pathology In Hereditary Hemorrhagic Telangiectasia Models, S. Ruiz, H. Zhao, P. Chandakkar, J. Papoin, P. K. Chatterjee, Y. Al-Abed, P. Wang, C. N. Metz, L. Blanc, P. Marambaud, +8 Additional Authors
Journal Articles
No abstract provided.
Lupus Autoantibodies Act As Positive Allosteric Modulators At Glun2a-Containing Nmda Receptors And Impair Spatial Memory, K. Chan, J. Nestor, T. S. Huerta, N. Certain, G. Moody, C. Kowal, P. T. Huerta, B. T. Volpe, B. Diamond, L. P. Wollmuth
Lupus Autoantibodies Act As Positive Allosteric Modulators At Glun2a-Containing Nmda Receptors And Impair Spatial Memory, K. Chan, J. Nestor, T. S. Huerta, N. Certain, G. Moody, C. Kowal, P. T. Huerta, B. T. Volpe, B. Diamond, L. P. Wollmuth
Journal Articles
No abstract provided.
Irf5 Genetic Risk Variants Drive Myeloid-Specific Irf5 Hyperactivation And Presymptomatic Sle, D. Li, B. Matta, S. Song, V. Nelson, K. Diggins, K. R. Simpfendorfer, P. K. Gregersen, P. Linsley, B. J. Barnes
Irf5 Genetic Risk Variants Drive Myeloid-Specific Irf5 Hyperactivation And Presymptomatic Sle, D. Li, B. Matta, S. Song, V. Nelson, K. Diggins, K. R. Simpfendorfer, P. K. Gregersen, P. Linsley, B. J. Barnes
Journal Articles
No abstract provided.
Pharmacological Prevention Of Surgery-Accelerated Metastasis In An Animal Model Of Osteosarcoma, M. P. Kallis, C. Maloney, B. Blank, S. Z. Soffer, M. Symons, B. M. Steinberg
Pharmacological Prevention Of Surgery-Accelerated Metastasis In An Animal Model Of Osteosarcoma, M. P. Kallis, C. Maloney, B. Blank, S. Z. Soffer, M. Symons, B. M. Steinberg
Journal Articles
No abstract provided.
Aid Overlapping And Polη Hotspots Are Key Features Of Evolutionary Variation Within The Human Antibody Heavy Chain (Ighv) Genes, C. Tang, D. Bagnara, N. Chiorazzi, M. D. Scharff, T. Maccarthy
Aid Overlapping And Polη Hotspots Are Key Features Of Evolutionary Variation Within The Human Antibody Heavy Chain (Ighv) Genes, C. Tang, D. Bagnara, N. Chiorazzi, M. D. Scharff, T. Maccarthy
Journal Articles
© Copyright © 2020 Tang, Bagnara, Chiorazzi, Scharff and MacCarthy. Somatic hypermutation (SHM) of the immunoglobulin variable (IgV) loci is a key process in antibody affinity maturation. The enzyme activation-induced deaminase (AID), initiates SHM by creating C → U mismatches on single-stranded DNA (ssDNA). AID has preferential hotspot motif targets in the context of WRC/GYW (W = A/T, R = A/G, Y = C/T) and particularly at WGCW overlapping hotspots where hotspots appear opposite each other on both strands. Subsequent recruitment of the low-fidelity DNA repair enzyme, Polymerase eta (Polη), during mismatch repair, creates additional mutations at WA/TW sites. Although …
Advanced Neuroimaging In Neuropsychiatric Systemic Lupus Erythematosus, M. Mackay, C. C. Tang, A. Vo
Advanced Neuroimaging In Neuropsychiatric Systemic Lupus Erythematosus, M. Mackay, C. C. Tang, A. Vo
Journal Articles
PURPOSE OF REVIEW: Neuropsychiatric lupus (NPSLE) comprises a disparate collection of syndromes affecting the central and peripheral nervous systems. Progress in the attribution of neuropsychiatric syndromes to SLE-related mechanisms and development of targeted treatment strategies has been impeded by a lack of objective imaging biomarkers that reflect specific neuropsychiatric syndromes and/or pathologic mechanisms. The present review addresses recent publications of neuroimaging techniques in NPSLE. RECENT FINDINGS: Imaging studies grouping all NPSLE syndromes together are unable to differentiate between NPSLE and non-NPSLE. In contrast, diffusion tensor imaging, FDG-PET, resting, and functional MRI techniques in patients with stable non-NPSLE demonstrate abnormal network …
Inhibition Of Irf5 Cellular Activity With Cell-Penetrating Peptides That Target Homodimerization, J. Banga, D. Srinivasan, C. Sun, C. D. Thompson, F. Milletti, K. Huang, S. Song, B. Matta, D. Li, B. J. Barnes, +17 Additional Authors
Inhibition Of Irf5 Cellular Activity With Cell-Penetrating Peptides That Target Homodimerization, J. Banga, D. Srinivasan, C. Sun, C. D. Thompson, F. Milletti, K. Huang, S. Song, B. Matta, D. Li, B. J. Barnes, +17 Additional Authors
Journal Articles
No abstract provided.
Anodal Block Permits Directional Vagus Nerve Stimulation, U. Ahmed, U. Ahmed, Y. C. Chang, M. Cracchiolo, M. F. Lopez, J. N. Tomaio, T. Datta-Chaudhuri, T. P. Zanos, L. Rieth, Y. Al-Abed, S. Zanos
Anodal Block Permits Directional Vagus Nerve Stimulation, U. Ahmed, U. Ahmed, Y. C. Chang, M. Cracchiolo, M. F. Lopez, J. N. Tomaio, T. Datta-Chaudhuri, T. P. Zanos, L. Rieth, Y. Al-Abed, S. Zanos
Journal Articles
© 2020, The Author(s). Vagus nerve stimulation (VNS) is a bioelectronic therapy for disorders of the brain and peripheral organs, and a tool to study the physiology of autonomic circuits. Selective activation of afferent or efferent vagal fibers can maximize efficacy and minimize off-target effects of VNS. Anodal block (ABL) has been used to achieve directional fiber activation in nerve stimulation. However, evidence for directional VNS with ABL has been scarce and inconsistent, and it is unknown whether ABL permits directional fiber activation with respect to functional effects of VNS. Through a series of vagotomies, we established physiological markers for …
Febrile Infant: Covid-19 In Addition To The Usual Suspects, E Robbins, Z Ilahi, P Roth
Febrile Infant: Covid-19 In Addition To The Usual Suspects, E Robbins, Z Ilahi, P Roth
Journal Articles
No abstract provided.
Management Of Covid-19 Myopericarditis With Reversal Of Cardiac Dysfunction After Blunting Of Cytokine Storm: A Case Report., A. Li, Y. Garcia-Bengochea, R. Stechel, B. M. Azari
Management Of Covid-19 Myopericarditis With Reversal Of Cardiac Dysfunction After Blunting Of Cytokine Storm: A Case Report., A. Li, Y. Garcia-Bengochea, R. Stechel, B. M. Azari
Journal Articles
Background:Coronavirus disease 2019 (COVID-19) is a syndrome that has been associated with multiple cardiac complications including myopericarditis. The pathophysiology and treatment for myopericarditis in the setting of COVID-19 infection is still under investigation. Case summary:We present a case of a 60-year-old male admitted for dyspnoea due to COVID-19. He developed new ST-segment elevation, elevated cardiac enzymes, severe left ventricular dysfunction, and high inflammatory markers in the setting of haemodynamic and respiratory collapse from the viral illness. He was diagnosed with COVID-19-induced myopericarditis. He showed rapid clinical improvement with a rapid wean off pressure support, resolution of electrocardiogram (ECG) findings, and …