Medicine and Health Sciences Commons^™

Ct Rapid Implementation In A 600+ Bed Hospital Serving 35 Counties In The Southeast, Christopher Burns Do, Adam Kassar Md, Jacob Beltz Md, Klie Hoffa, Peter Britt

Radiology

No abstract provided.

Unilateral And Bilateral Lower-Body Resistance Training Does Not Transfer Equally To Sprint And Change Of Direction Performance, Brendyn B. Appleby, Stuart J. Cormack, Robert U. Newton

Research outputs 2014 to 2021

Given maximal strength can be developed using bilateral or unilateral resistance training, the purpose of this study was to determine the magnitude of transfer of unilateral or bilateral resistance training to sprint and change of direction (COD) performance. Thirty-three trained participants (average training age = 5.4 ± 2.9 years and 1 repetition maximum [1RM] 90° squat = 177.6 ± 26.7 kg) completed either a bilateral group (BIL, n = 13), unilateral (UNI, n = 10), or comparison (COM, n = 10) 18-week randomized controlled training design. Training involved 2 lower-body, volume-load-matched resistance sessions per week (6-8 sets × 4-8 reps …

A Rapid Population Assessment Method For Wild Pigs Using Baited Cameras At 3 Study Site, Peter E. Schlichting, James C. Beasley, Raoul K. Boughton, Amy J. Davis, Kim M. Pepin, Michael P. Glow, Ryan S. Miller, Kurt C. Vercautern, Jesse S. Lewis

United States Department of Agriculture Wildlife Services: Staff Publications

Reliable and efficient population estimates are a critical need for effective management of invasive wild pigs (Sus scrofa). We evaluated the use of 10‐day camera grids for rapid population assessment (RPA) of wild pigs at 3 study sites that varied in vegetation communities and wild pig densities. Study areas included Buck Island Ranch, Florida; Tejon Ranch, California; and the Savannah River Site, South Carolina, USA, during 2016–2018. Rapid population assessments grids were composed of baited camera traps spaced approximately 500 or 750 m apart. Two RPA grids were deployed per study site and each grid was deployed twice (4–6 months …

In Vitro And In Vivo Effects Of Flavonoids On Peripheral Neuropathic Pain, Paramita Basu, Arpita Basu

Kinesiology and Nutrition Sciences Faculty Research

Neuropathic pain is a common symptom and is associated with an impaired quality of life. It is caused by the lesion or disease of the somatosensory system. Neuropathic pain syndromes can be subdivided into two categories: central and peripheral neuropathic pain. The present review highlights the peripheral neuropathic models, including spared nerve injury, spinal nerve ligation, partial sciatic nerve injury, diabetes-induced neuropathy, chemotherapy-induced neuropathy, chronic constriction injury, and related conditions. The drugs which are currently used to attenuate peripheral neuropathy, such as antidepressants, anticonvulsants, baclofen, and clonidine, are associated with adverse side effects. These negative side effects necessitate the investigation …

Variable Magnitude And Frequency Financial Reinforcement Is Effective At Increasing Adults’ Free-Living Physical Activity, Vincent Berardi, Melbourne Hovell, Jane C. Hurley, Christine B. Phillips, John Belletierre, Michael Todd, Marc A. Adams

Psychology Faculty Articles and Research

Financial rewards can increase health behaviors, but little research has quantified the effects of different reinforcement schedules on this process. This analysis compares the average moderate-to-vigorous physical activity (MVPA) associated with six distinct positive reinforcement schedules implemented within a physical activity promotion clinical trial. In this trial, participants (N = 512) wore an accelerometer for 1 year and were prescribed one of two types of MVPA goals: a static 30-min goal or an adaptive goal based on the MVPA produced over the previous 9 days. As participants met goals, they transitioned through a sequence of reinforcement stages, beginning with …

Summer Research Internships In Agricultural Biotechnology For Off-Campus Undergraduate Students, Aaron J. Thomas

Funded Research Records

No abstract provided.

Abortion Case May Not Overturn Roe, But Could Effectively Nullify It, A. Benjamin Spencer

Popular Media

No abstract provided.

Cell Type Composition And Circuit Organization Of Clonally Related Excitatory Neurons In The Juvenile Mouse Neocortex, Cathryn R Cadwell, Federico Scala, Paul G Fahey, Dmitry Kobak, Shalaka Mulherkar, Fabian H Sinz, Stelios Papadopoulos, Zheng H Tan, Per Johnsson, Leonard Hartmanis, Shuang Li, Ronald J Cotton, Kimberley F Tolias, Rickard Sandberg, Philipp Berens, Xiaolong Jiang, Andreas Savas Tolias

Faculty, Staff and Students Publications

Clones of excitatory neurons derived from a common progenitor have been proposed to serve as elementary information processing modules in the neocortex. To characterize the cell types and circuit diagram of clonally related excitatory neurons, we performed multi-cell patch clamp recordings and Patch-seq on neurons derived from Nestin-positive progenitors labeled by tamoxifen induction at embryonic day 10.5. The resulting clones are derived from two radial glia on average, span cortical layers 2–6, and are composed of a random sampling of transcriptomic cell types. We find an interaction between shared lineage and connection type: related neurons are more likely to …

Secondary Analysis Of Health-Related Data, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Reduced Cognitive Assessment Scores Among Individuals With Magnetic Resonance Imaging-Detected Vascular Brain Injury, Sonia S Anand, Matthias G Friedrich, Dipika Desai, Karleen M Schulze, Philip Awadalla, David Busseuil, Trevor J B Dummer, Sébastien Jacquemont, Alexander Dick, David Kelton, Anish Kirpalani, Scott A Lear, Jonathan Leipsic, Michael D Noseworthy, Louise Parker, Grace Parraga, Paul Poirier, Paula Robson, Jean-Claude Tardif, Koon Teo, Jennifer Vena, Salim Yusuf, Alan R Moody, Sandra E Black, Eric E Smith

Medical Biophysics Publications

Background and Purpose- Little is known about the association between covert vascular brain injury and cognitive impairment in middle-aged populations. We investigated if scores on a cognitive screen were lower in individuals with higher cardiovascular risk, and those with covert vascular brain injury. Methods- Seven thousand five hundred forty-seven adults, aged 35 to 69 years, free of cardiovascular disease underwent a cognitive assessment using the Digital Symbol Substitution test and Montreal Cognitive Assessment, and magnetic resonance imaging (MRI) to detect covert vascular brain injury (high white matter hyperintensities, lacunar, and nonlacunar brain infarctions). Cardiovascular risk factors were quantified using the …

Implementation Science Nur 681, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Self-Talk: Mentoring And Empowering Faculty To Contribute To Organizational Change, Brian Culp

Faculty Articles

We can effectively mentor if in possession of qualities to empower mentees, which include: effective communication skills, knowledge of the professional realm, enthusiasm, passion and the ability to create an equitable and supportive organizational environment with the mentee. The authors of this article propose that self-talk (ST) or inner speech is a helpful means of inspiring mentors, colleagues, teachers, and friends in navigating communication challenges with themselves and others. A three-step approach to implementing ST for the purpose of mentoring involves: (1) awareness of the ST they are currently using; (2) follow-up with the mentee’s active reflection of and recording …

Modulation Of The Pol Ii Ctd Phosphorylation Code By Rac1 And Cdc42 Small Gtpases In Cultured Human Cancer Cells And Its Implication For Developing A Synthetic-Lethal Cancer Therapy, Bo Zhang, Xuelin Zhong, Moira Sauane, Yihong Zhao, Zhi-Liang Zheng

Publications and Research

Rho GTPases, including Rho, Cdc42, Rac and ROP subfamilies, are key signaling molecules in RNA polymerase II (Pol II) transcriptional control. Our prior work has shown that plant ROP and yeast Cdc42 GTPases similarly modulate Ser2 and Ser5 phosphorylation status of the C-terminal domain (CTD) of the Pol II largest subunit by regulating CTD phosphatase degradation. Here, we present genetic and pharmacological evidence showing that Cdc42 and Rac1 GTPase signaling modulates a similar CTD Ser2 and Ser5 phosphorylation code in cultured human cancer cells. While siRNA knockdown of Cdc42 and Rac1, respectively, in HeLa cells increased the level of CTD …

Food Allergy Among University Students: Uncharted Territory., Ali Hassan, Amna Alsaihati, Malak Al Shammari, Haitham Alaithan, Wejdan Al-Johani, Nouf Alshamlan, Salman Aljubran

Manuscripts, Articles, Book Chapters and Other Papers

Background: Food allergy is a growing global health concern, with limited studies conducted in developing countries. High-risk behavior regarding allergies is common among young adults, making them prone to severe allergic reactions. This study aimed to estimate the prevalence of food allergies among Imam Abdulrahman Bin Faisal University (IAU) students and to determine the rate of high-risk behaviors in this group.

Methods: An online survey was conducted among IAU students enrolled between the academic years of 2008 and 2018. The survey addressed food allergies with respect to age of onset, allergy testing, self-injectable epinephrine (SIE) prescription, associated allergic conditions, and …

Barriers To Occupational Heat Stress Risk Adaptation Of Mining Workers In Ghana, Victor Fannam Nunfam, Kwadwo Adusei-Asante, Kwasi Frimpong, Eddie John Van Etten, Jacques Oosthuizen

Research outputs 2014 to 2021

Increasing temperature and climate warming impacts are aggravating the vulnerability of workers to occupational heat stress. Adaptation and social protection strategies have become crucial to enhance workers’ health, safety, productive capacity and social lives. However, the effective implementation of work-related heat stress adaptation mechanisms appears to be receiving little attention. This study assessed the barriers to occupational heat stress adaptation and social protection strategies of mining workers in Ghana. Based on a mixed methods approach, focus group discussions and questionnaires were used to elicit data from 320 mining workers. Workers’ adaptation strategies (water intake, wearing loose and light-coloured clothing, participating …

A Smartphone App For Self-Management Of Heart Failure In Older African Americans: Feasibility And Usability Study, Sue P. Heiney, Sara B. Donevant, Swann Arp Adams, Pearman D. Parker, Hongtu Chen, Sue Levkoff

Faculty Publications

Background: Mobile health (mHealth) apps are dramatically changing how patients and providers manage and monitor chronic health conditions, especially in the area of self-monitoring. African Americans have higher mortality rates from heart failure than other racial groups in the United States. Therefore, self-management of heart failure may improve health outcomes for African American patients.

Objective: The aim of the present study was to determine the feasibility of using an mHealth app, and explore the outcomes of quality of life, including self-care maintenance, management, and confidence, among African American patients managing their condition after discharge with a diagnosis of heart failure. …

What Really Works To Keep Coronavirus Away? 4 Questions Answered By A Public Health Professional, Brian Labus

Environmental & Global Health Faculty Research

Editor’s note: The World Health Organization has declared that COVID-19, the disease caused by the new coronavirus, has a higher fatality rate than the flu. As of March 4, 2020, nine deaths have been reported in the U.S. Brian Labus, a professor of public health, provides essential safety information for you, from disinfectants to storing food and supplies.

A Nwb-Based Dataset And Processing Pipeline Of Human Single-Neuron Activity During A Declarative Memory Task, N. Chandravadia, D. Liang, A. G. P. Schjetnan, A. Carlson, M. Faraut, J. M. Chung, C. M. Reed, B. Dichter, Uri Maoz, S. K. Kalia, T. A. Valiante, A. N. Mamelak, U. Rutishauser

Psychology Faculty Articles and Research

A challenge for data sharing in systems neuroscience is the multitude of different data formats used. Neurodata Without Borders: Neurophysiology 2.0 (NWB:N) has emerged as a standardized data format for the storage of cellular-level data together with meta-data, stimulus information, and behavior. A key next step to facilitate NWB:N adoption is to provide easy to use processing pipelines to import/export data from/to NWB:N. Here, we present a NWB-formatted dataset of 1863 single neurons recorded from the medial temporal lobes of 59 human subjects undergoing intracranial monitoring while they performed a recognition memory task. We provide code to analyze and export/import …

Why Are Some Cases Not On Track? An Item Analysis Of The Assessment For Signal Cases During Inpatient Psychotherapy, Thomas Probst, Maria Kleinstäuber, Michael J. Lambert, Karin Tritt, Christoph Pieh, Thomas H. Loew, Reiner W. Dahlbender, Jamie Delgadillo

Psychology Faculty Publications

Within the Routine Outcome Monitoring system “OQ-Analyst,” the questionnaire “Assessment for Signal Cases” (ASC) supports therapists in detecting potential reasons for not-on-track trajectories. Factor analysis and a machine learning algorithm (LASSO with 10-fold cross-validation) were applied, and potential predictors of not-on-track classifications were tested using logistic multilevel modeling methods. The factor analysis revealed a shortened (30 items) version of the ASC with good internal consistency (α = 0.72–0.89) and excellent predictive value (area under the curve = 0.98; positive predictive value = 0.95; negative predictive value = 0.94). Item-level analyses showed that interpersonal problems captured by specific ASC items (not …

Error-Corrected Sequencing Strategies Enable Comprehensive Detection Of Leukemic Mutations Relevant For Diagnosis And Minimal Residual Disease Monitoring, Erin L Crowgey, Nitin Mahajan, Wing Hing Wong, Anilkumar Gopalakrishnapillai, Sonali P Barwe, E Anders Kolb, Todd E Druley

2020-Current year OA Pubs

BACKGROUND: Pediatric leukemias have a diverse genomic landscape associated with complex structural variants, including gene fusions, insertions and deletions, and single nucleotide variants. Routine karyotype and fluorescence in situ hybridization (FISH) techniques lack sensitivity for smaller genomic alternations. Next-generation sequencing (NGS) assays are being increasingly utilized for assessment of these various lesions. However, standard NGS lacks quantitative sensitivity for minimal residual disease (MRD) surveillance due to an inherently high error rate.

METHODS: Primary bone marrow samples from pediatric leukemia (n = 32) and adult leukemia subjects (n = 5), cell line MV4-11, and an umbilical cord sample were utilized for …

Integrating Aviation Technology, Emergency Services, And Human Resilience: Considerations From Social Scientists, Chelsea A. Lenoble Ph.D., Joel M. Billings Ph.D., Allison A. Kwesell Ph.D., Ray H. Chang Ph.D.

National Training Aircraft Symposium (NTAS)

Unmanned aerial systems (UAS) have a range of applications within the field of disaster response. This presentation offers a novel framework of psychosocial considerations designed to advance UAS and disaster management integration. Social scientists highlight important challenges to the effective integration of three primary entities: UAS, the team of teams that responds to disasters, and populations affected by disasters.

The presentation adopts an emerging theoretical perspective on the intersection between UAS capabilities and disaster phases and extends it by bringing necessary attention to social science issues. Specifically, the framework outlines psychosocial considerations and areas of improvement for preparation (training), response …

Dynamic Interstitial Cell Response During Myocardial Infarction Predicts Resilience To Rupture In Genetically Diverse Mice., Elvira Forte, Daniel A Skelly, Mandy Chen, Sandra Daigle, Kaesi A Morelli, Olivia Hon, Vivek M. Philip, Mauro W Costa, Nadia Rosenthal, Milena B Furtado

Faculty Research 2020

Cardiac ischemia leads to the loss of myocardial tissue and the activation of a repair process that culminates in the formation of a scar whose structural characteristics dictate propensity to favorable healing or detrimental cardiac wall rupture. To elucidate the cellular processes underlying scar formation, here we perform unbiased single-cell mRNA sequencing of interstitial cells isolated from infarcted mouse hearts carrying a genetic tracer that labels epicardial-derived cells. Sixteen interstitial cell clusters are revealed, five of which were of epicardial origin. Focusing on stromal cells, we define 11 sub-clusters, including diverse cell states of epicardial- and endocardial-derived fibroblasts. Comparing transcript …

Cardiac Biomarkers And Subsequent Risk Of Hospitalization With Bleeding In The Community: Atherosclerosis Risk In Communities Study, Lena Mathews, Junichi Ishigami, Ning Ding, Ron C. Hoogeveen, Anna Kucharska-Newton, Christie M. Ballantyne, Rebecca Gottesman, Elizabeth Selvin, Kunihiro Matsushita

Epidemiology and Environmental Health Faculty Publications

Background

hs-cTnT (high-sensitivity cardiac troponin T), but not NT-proBNP (N-terminal pro-B natriuretic peptide), has been shown to predict bleeding in patients with atrial fibrillation. Whether these biomarkers are independently associated with bleeding in the general population is unknown.

Methods and Results

We used Cox proportional hazards models to examine the association of hs‐cTnT and NT‐proBNP with incident bleeding (defined by International Classification of Diseases, Ninth Revision [ICD‐9] codes) among 9550 middle‐aged men and women without a history of cardiovascular disease or bleeding. There were 847 hospitalizations with bleeding (92% from gastrointestinal bleeding) during a median follow‐up of …

A Brief Report On A Facilitated Approach To Connect Cooperative Extension Southern Region State-Level Health Specialists, Samantha M. Harden, Lisa Washburn, Alison Berg, Ninfa Pena-Purcell, Heather Norman-Burgdolf, Nancy Franz

Dietetics and Human Nutrition Faculty Publications

Improving the nation’s health will require collaboration among many stakeholders and systems, including representatives from Cooperative Extension Services (CES). This paper describes the process of establishing a multistate collaboration and discusses initial outcomes of a third-party facilitated participatory planning meeting. State-level specialists with expertise and responsibilities in “health” promotion participated. Satisfaction with meeting format; feasibility, acceptability, and appropriateness of the proposed approach to public health impact; and general meeting feedback were collected through a survey and cultural artifacts (e.g., notes, worksheets). Preparation and attendance costs were captured. Seventeen of the 20 attendees (85%) responded to the survey and reported the …

Cannabis Chemistry And Pharmacognosy, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Cannabis Chemistry And Pharmacognosy, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Coronavirus (“Covid-19”) Webpage, March 3, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo from the Director of Risk Management announcing the members of the COVID-19 Task Force to coordinate the response to the disease.

From The Provost: Covid-19 Preparations, March 3, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo from the Provost outlining steps taken up to March 3, 2020 and outlining potential actions should they be necessary to ensure the completion of the spring semester.

Calcified Infratemporal Mass: Osteochondroma, Galal Omami

Oral Health Practice Faculty Publications

No abstract provided.

Cannabis Therapeutics Bps 314, Joanna Burkhardt

Library Impact Statements

No abstract provided.