Medicine and Health Sciences Commons^™

A Message To Our Students About Move-Out, March 19, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo to students living in the dormitories concerning the move-out of those who can move to their family homes, detailing the days and times students can do so.

2020-03-19_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 2 p.m., with yesterday’s COVID-19 positive results included as of 10 a.m.

The website contained the tables Confirmed COVID-19 Cases by County, Tests, Percentage of Cases by Sex, and Percentage of Cases by Age.

Functional Blockade Of E-Selectin In Tumor-Associated Vessels Enhances Anti-Tumor Effect Of Doxorubicin In Breast Cancer, Yoshihiro Morita, Macall Leslie, Hiroyasu Kameyama, Ganesh L R Lokesh, Norihisa Ichimura, Rachel Davis, Natalie Hills, Nafis Hasan, Roy Zhang, Yuji Kondo, David G Gorenstein, David E Volk, Inna Chervoneva, Hallgeir Rui, Takemi Tanaka

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Chemotherapy is a mainstay of treatment for solid tumors. However, little is known about how therapy-induced immune cell infiltration may affect therapy response. We found substantial CD45+ immune cell density adjacent to E-selectin expressing inflamed vessels in doxorubicin (DOX)-treated residual human breast tumors. While CD45 level was significantly elevated in DOX-treated wildtype mice, it remained unchanged in DOX-treated tumors from E-selectin null mice. Similarly, intravenous administration of anti-E-selectin aptamer (ESTA) resulted in a significant reduction in CD45+ immune cell density in DOX-treated residual tumors, which coincided with a delay in tumor growth and lung metastasis in MMTV-pyMT mice. Additionally, both …

The Importance Of Considering A Wide Range Of Differential Diagnoses Forpatients Presenting With Complaints Of Urinary Incontinence: Acase Report., Katelyn E Tondo-Steele, Nicole M Book

Women’s Health Articles

Urinary incontinence (UI) is common in women and is often associated with decreased quality of life. It is important to consider a range of wide differential diagnoses when evaluating a patient presenting with presumed with UI. This case describes a patient referred to urogynecology for urinary incontinence caused by a common, benign and usually asymptomatic gynecologic condition: nabothian cysts. However, based on presentation and imaging, there was concern about a more serious condition: adenoma malignum. This case emphasizes the importance of considering a wide range of differential diagnoses and describes several important differential diagnoses associated with urinary incontinence.

The Attitude Of Medical Practices Toward Lgbt Older Adults Before And After Intervention, Lynn M. Wilson Do, Mackenzi B. Kim Md, Nyann Biery Ms, Brenda Frutos Mph, Ches

Department of Family Medicine

No abstract provided.

Understanding The Dimensions Of Medical Crowdfunding: A Visual Analytics Approach, Jie Ren, Viju Raghupathi, Wullianallur Raghupathi

Publications and Research

Background: Medical crowdfunding has emerged as a growing field for fundraising opportunities. Some environmental trends have driven the emergence of campaigns to raise funds for medical care. These trends include lack of medical insurance, economic backlash following the 2008 financial collapse, and shortcomings of health care regulations.

Objective: Research regarding crowdfunding campaign use, reasons, and effects on the provision of medical care and individual relationships in health systems is limited. This study aimed to explore the nature and dimensions of the phenomenon of medical crowdfunding using a visual analytics approach and data crawled from the GoFundMe crowdfunding platform in 2019. …

Development And Psychometrics Of The English Version Of The Itch Cognitions Questionnaire, Carolyn J. Heckman, Christina Schut, Mary Riley, Anke Ehlers, Rodrigo Valdes-Rodriguez, Jörg Kupfer, Uwe Gieler, Jerod L. Stapleton

Health, Behavior & Society Faculty Publications

BACKGROUND: The aim of this study was to validate the English version of the Itch Cognition Questionnaire in a sample of patients with chronic itch due to psoriasis or atopic dermatitis. An English-language version of an instrument assessing itch-related cognitions is needed since cognitions can contribute to a worsening of itch, and chronic itch is prevalent in English-speaking counties and internationally.

METHODS: The German Itch Cognitions Questionnaire was translated into English, and cognitive interviewing was conducted to finalize item wording. Internal and test-retest reliability, item discrimination, responsiveness to change, and construct, convergent, and discriminant validity were assessed in a national …

Neutrophil Infiltration Into The Cervical Compartment Is Suppressed By Hiv Infection, Madeline Maschka

Honors Program: Senior Projects (Public)

Human Papillomavirus (HPV), is a small circular dsDNA virus with at least 200 different genotypes; each genotype is identified by at least 10% difference at the DNA level in the L1 capsid gene. Each HPV genotype affects the body in different tissues, either mucosal or cutaneous. Mucosal HPVs type 16 and 18 are known as high-risk strains, since HPV infection is the most common cause of cervical cancer and plays a central role in formation of precancerous lesions. Human immunodeficiency virus (HIV) damages the body’s immune system by targeting CD4+ T cells. Once CD4+ T cells are infected, the body …

Covid-19: Playing The Long Game For Your Mental Health, Mary Kate Schutt

Population Health Research Brief Series

This issue brief provides a new lens to view the pandemic of COVID-19 and offers simple, practical, and action-oriented ways to mange your mental health for the long term during this time of uncertainty.

As Schools Close Due To The Coronavirus, Mental Health Care For Children Must Be Protected, Xiaoyan Zhang

Population Health Research Brief Series

This data slice highlights the expansive nation-wide school closings due to COVID-19 and encourages providers and government bodies to support the mental health needs of students across the country.

A Comparison Of Verbal Feedback And Video Feedback To Improve Dance Skills, Shreeya Sudhir Deshmukh

USF Tampa Graduate Theses and Dissertations

Research has shown that video feedback and verbal feedback can improve a variety of skills related to several sports. The purpose of this study was to compare the effectiveness of these two forms of feedback for improving dance skills. In this study, the dance skills of three participants were assessed. Verbal feedback and video feedback were implemented using a multiple baseline across participants with an embedded alternating treatments design to allow for a direct comparison of the interventions. The results indicated that verbal feedback was more effective for one participant and video feedback was more effective for one participant. More …

Functional Blockade Of E-Selectin In Tumor-Associated Vessels Enhances Anti-Tumor Effect Of Doxorubicin In Breast Cancer, Yoshihiro Morita, Macall Leslie, Hiroyasu Kameyama, Ganesh L. Lokesh, Norihisa Ichimura, Rachel Davis, Natalie Hills, Nafis Hasan, Roy Zhang, Yuji Kondo, David G. Gorenstein, David E. Volk, Inna Chervoneva, Hallgeir Rui, Takemi Tanaka

Faculty Publications

Chemotherapy is a mainstay of treatment for solid tumors. However, little is known about how therapy-induced immune cell infiltration may affect therapy response. We found substantial CD45 immune cell density adjacent to E-selectin expressing inflamed vessels in doxorubicin (DOX)-treated residual human breast tumors. While CD45 level was significantly elevated in DOX-treated wildtype mice, it remained unchanged in DOX-treated tumors from E-selectin null mice. Similarly, intravenous administration of anti-E-selectin aptamer (ESTA) resulted in a significant reduction in CD45 immune cell density in DOX-treated residual tumors, which coincided with a delay in tumor growth and lung metastasis in MMTV-pyMT mice. Additionally, both …

Male Luts – Introduction And Overview, Thenappan Chandrasekar, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Outline & Goals

• Background – What are “LUTS”?

• Anatomy

• Pathophysiology

• Storage – bladder filling symptoms
• Voiding – urine flow symptoms
• Post-micturition

• Major etiologies and management

• BPH / BOO
• OAB
• Nocturia

• Related to Prostate Cancer?

Mob Family Proteins: Regulatory Partners In Hippo And Hippo-Like Intracellular Signaling Pathways, Juan Carlos Duhart, Laurel A. Raftery

Life Sciences Faculty Research

Studies in yeast first delineated the function of Mob proteins in kinase pathways that regulate cell division and shape; in multicellular eukaryotes Mobs regulate tissue growth and morphogenesis. In animals, Mobs are adaptors in Hippo signaling, an intracellular signal-transduction pathway that restricts growth, impacting the development and homeostasis of animal organs. Central to Hippo signaling are the Nuclear Dbf2-Related (NDR) kinases, Warts and LATS1 and LATS2, in flies and mammals, respectively. A second Hippo-like signaling pathway has been uncovered in animals, which regulates cell and tissue morphogenesis. Central to this emergent pathway are the NDR kinases, Tricornered, STK38, and STK38L. …

How To Stop Touching Your Face To Minimize Spread Of Coronavirus And Other Germs, Stephen D. Benning, Brian Labus, Kimberly Barchard

Psychology Faculty Research

Public health officials consistently promote hand-washing as a way for people to protect themselves from the COVID-19 coronavirus. However, this virus can live on metal and plastic for days, so simply adjusting your eyeglasses with unwashed hands may be enough to infect yourself. Thus, the Centers for Disease Control and Prevention and the World Health Organization have been telling people to stop touching their faces.

Proteinuria, Goni Katz-Greenberg, Md

Department of Family & Community Medicine Presentations and Grand Rounds

Outline and Objectives

• Definition
• Screening/Measurement
• Etiology
• Treatment

Suddenly, Grace Meharg

Reflections, Poetry, Photos, and other Writings

This is a piece I wrote on March 18, 2020 reflecting on the last week of Taylor and all of the rapid changes that occurred which brought all of us to scatter.

Online Coursework Extended Through Spring, Summer, March 18, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo to the campus community concerning coursework for the spring and summer semesters and the status of the residence halls, the student health clinic, and commencement.

Statement From Board Of Regents President Mike Richards Declaring Regents State Of Emergency, March 18, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo from the President of the Board of Regents declaring a state of emergency and waiving some Board policies and administrative rules regarding sick leave and program changes.

Uni Encourages Employees To Work Remotely, March 18, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo from UNI leadership encouraging employees to work remotely if their duties allow.

Transcutaneous Auricular Vagus Nerve Stimulation-Paired Rehabilitation For Oromotor Feeding Problems In Newborns: An Open-Label Pilot Study, Bashar W. Badran, Dorothea D. Jenkins, Daniel Cook, Sean Thompson, Morgan Darcy, William H. Devries, Georgia Mappin, Philipp Summers, Marom Bikson, Mark S. George

Publications and Research

Neonates born premature or who suffer brain injury at birth often have oral feeding dysfunction and do not meet oral intake requirements needed for discharge. Low oral intake volumes result in extended stays in the hospital (>2 months) and can lead to surgical implant and explant of a gastrostomy tube (G-tube). Prior work suggests pairing vagus nerve stimulation (VNS) with motor activity accelerates functional improvements after stroke, and transcutaneous auricular VNS (taVNS) has emerged as promising noninvasive form of VNS. Pairing taVNS with bottle-feeding rehabilitation may improve oromotor coordination and lead to improved oral intake volumes, ultimately avoiding the …

2020-03-18 A Message From Chancellor Roth (2), Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

2020-03-18 A Message From Chancellor Roth (1), Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

Ideology Affects Trust In Science Agencies During A Pandemic, Lawrence C. Hamilton, Thomas G. Safford

Carsey Publications

In this perspectives brief, authors Lawrence Hamilton and Thomas Safford discuss the importance of government and public respect for scientific advice in mitigating the impacts of COVID-19. Striking political divisions in attitudes toward science have recently been evident in U.S. government statements and actions regarding the pandemic, and in opinions or behavior reported by general-public surveys. Although the COVID-19 crisis is breaking news, these political divisions in respect for science during a pandemic have deeper roots. A nationwide survey conducted by Carsey School researchers in 2016, immediately after the elections, found 25-point gaps between Trump and Clinton voters, or between …

2020-03-18_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 2 p.m., with yesterday’s COVID-19 positive results included as of midnight.

The website contained the tables Confirmed COVID-19 Cases by County, Tests, Percentage of Cases by Sex, and Percentage of Cases by Age.

Two Implementation Models Of Workers' Health Education Programs In Egypt: What Works? What Doesn't Work?, Nahla G. Abdel-Tawab, Norhan Bader, Elizabeth Tobey, Aparna Jain

Reproductive Health

This brief presents findings from two models of workers’ health education programs implemented by the Evidence Project/Population Council in Egypt. The two interventions aimed to increase family planning (FP) service demand among young people aged 18–35 in Port Said and urban Souhag. In Port Said, male and female factory workers who were trained as peer educators shared family planning/reproductive health (FP/RH) information with fellow factory workers, distributed communication materials, and provided referrals to infirmary nurses trained in FP counseling. In Souhag, male and female peer educators were trained to provide integrated FP/RH and livelihood workshops to job seekers. Results of …

Role Of Changes In Sars-Cov-2 Spike Protein In The Interaction With The Human Ace2 Receptor: An In Silico Analysis, Joseph Thomas Ortega

Faculty Scholarship

Many human viral diseases are a consequence of a zoonotic event. Some of the diseases caused by these zoono- tic events have affected millions of people around the world, some of which have resulted in high rates of mor- bidity/mortality in humans. Changes in the viral proteins that function as ligands of the host receptor may pro- mote the spillover between species. The most recent of these zoonotic events that have caused an ongoing epi- demic of high magnitude is the Covid-19 epidemics caused by SARS-CoV-2. The aim of this study was to de- termine the mutation(s) in the sequence …

Exploring The Experiences Of Community Health Workers In The Dominican Republic Using Photovoice, Johnathan Steppe

Doctorate of Nursing Science Dissertations

In order to mitigate the growing health worker shortage, many low-middle income countries (LMICs) use community health workers (CHWs) to extend health services to underserved communities. Community health workers are laypersons with minimal training who provide basic health services for they communities in which they live. Although past research has demonstrated that CHWs can provide appropriate care that contributes to positive health outcomes, many CHW programs fail to achieve long-term sustainability. As the largest group of health professionals, nurses often work closely with CHWs, and are therefore well-positioned to support sustainability of CHW programs.

The purpose of this participatory action …

Midwives’ And Women’S Perception On Moyo Fetal Heart Rate Monitor For Intrapartum Fetal Heart Rate Monitoring; A Cross-Sectional Study, Paschal Mdoe, Anita Yeconia, Fanuel Buu, Simeon Kusulla, Ladislaus Blacy, Estomih Mduma, Godfrey Guga, Hussein Kidanto

Obstetrics and Gynaecology, East Africa

Background: The annual global neonatal mortality stands at 2.5 million deaths, 1 million of them dying within the first day of life. An additional 2.6 million are stillborn globally, the majority of them due to intrapartum events. Optimal fetal heart rate (FHR) monitoring has the potential to timely detect fetuses at risk and, if coupled with timely obstetric responses may save more newborns. Moyo is a new Doppler with nine crystals capable of monitoring FHR both intermittently and continuously.

Aim: To assess women’s and midwives’ opinions on the use of Moyo for intrapartum FHR monitoring.

Methods: We conducted a cross-sectional …

The Unique Demands Of Playing Posture On Youth Violinists And Violists, Liam Carroll

Honors Program: Senior Projects (Public)

The high prevalence of performing arts injuries is an acknowledged challenge facing the performing arts medicine community. The injuries seem to affect string players the most among orchestral musicians, specifically violinists and violists. The asymmetrical posture, head and neck displacement, and spinal displacement required by the posture to play violin and viola can lead to discomfort or injury in the performer. Performance related musculoskeletal disorders (PRMDs) can have an adverse impact on the life of a musician, preventing them from performing or making it uncomfortable. While there is a large body of research on PRMDs relating to adult musicians, there …