Medicine and Health Sciences Commons^™

Transverse Myelitis Masquerading As Cauda Equina Syndrome, Stroke And Cervical Myelopathy, Sally Shin Jie Chan, Arun-Kumar Kaliya-Perumal, Quan You Yeo, Jacob Y.L. Oh

BioMedicine

Transverse myelitis is an uncommon but well-defined neurological syndrome. However, a high index of suspicion is needed to diagnose this condition, especially when it occurs in concomitance with preexisting spinal canal stenosis. We report our patient, a 48 year old male, who initially presented to our spine clinic with acute onset unilateral lower limb weakness associated with urinary retention, which was suspected to be cauda equina syndrome due to a prolapsed intervertebral disc. However, initial magnetic resonance (MR) imaging showed only mild spinal canal stenosis from L2-L5 and C3- C6 levels; thus, the possibility of cauda equina syndrome was ruled …

Hyperuricemia Might Be An Early Manifestation Of Undiagnosed Adult Leukemia In A Population-Based Cohort Study, Shih-Wei Lai, Cheng-Li Lin, Kuan-Fu Liao

BioMedicine

Background/Objective. No published population-based study investigates the association between hyperuricemia and undiagnosed adult leukemia in Taiwan. The aim of the study was to investigate whether hyperuricemia might be an early manifestation of undiagnosed adult leukemia in Taiwan. Methods. A population-based cohort study was conducted to analyze the database of the Taiwan National Health Insurance Program. There were 47708 subjects aged 20 to 84 years with newly diagnosed hyperuricemia as the hyperuricemia group from 2000 to 2013, and 190832 randomly selected subjects without hyperuricemia as the non-hyperuricemia group. The hyperuricemia group and the non-hyperuricemia group were followed for one …

Evaluating Co-Occurrence Of Depression And Sexual Dysfunction And Related Factors Among Iranian Rural Women: A Population-Based Study, Raheleh Khademi, Seyed Hamzeh Hosseini, Hamid Sharif Nia, Soghra Khani

BioMedicine

Background and Objectives: Sexual dysfunction and mood disorders have a high prevalence rate and their co-occurrence has been reported in previous studies. This study aimed to determine the prevalence of co-occurrence of sexual dysfunction and depression and related factors in women.

Materials and Methods: This descriptive-analytical study was carried out on 826 married rural women aged 15-49 years in Sari, Iran in 2018, selected by random sampling. The participants filled the demographic and fertility questionnaires, as well as Beck’s Depression Inventory and Female Sexual Function Index (FSFI).

Results: In this study, 18% of the participants experienced the co-occurrence of depression …

Effect Of Evening Primrose Oil On Postoperative Pain After Appendectomy: A Double-Blind, Randomized, Clinical Trial, Manijeh Y. Moghadam, Mohammad Nemat-Shahi, Davood Soroosh, Mahbobeh Nemat-Shahi, Atefeh Asadi

BioMedicine

Background and objective: Despite advances in surgical techniques and pharmacology, postoperative pain remains a common problem after appendectomy, and its management continues to be suboptimal. The aim of this study was to evaluate the effect of evening primrose oil on the reduction of postoperative pain after appendectomy.

Materials and Methods: In a double-blind, randomized, clinical trial, a total of 80 adults patients with acute appendicitis who were undergoing appendectomy at the Shahid Beheshti Emdad Hospital in Sabzevar, were included. Patients were randomly allocated into two equally sized groups (n=40). In postoperative period and after recovering from the anesthesia, …

An Immunohistochemical Study Of Her2 Expression In Primary Brain Tumors, Mazaher Ramezani, Shadi Siami, Mansour Rezaei, Sedigheh Khazaei, Masoud Sadeghi

BioMedicine

Background: Primary brain tumors (PBTs) include any tumor in the brain whose prognosis is weak because of their histological characteristics. Aim: Herein, this study aimed to assess the HER2 tumor marker frequency in PBTs. Materials and methods: This study was done on the samples of primary brain tumor diagnosis from 2008 to 2015. Results: Out of 107 patients of brain tumor that had a mean age of 40.4 years (61.7% men), the most common location of the tumor was in the supratentorial region (63.85% cases). The prevalence of high-grade astrocytoma (HGA) and low-grade astrocytoma (LGA) at diagnosis was 43.9% …

Methods Of Effective Low-Level Laser Therapy In The Treatment Of Patients With Bronchial Asthma, Sergey Vladimirovich Moskvin, Aleksandr A. Khadartsev

BioMedicine

Bronchial asthma is an autoimmune disease, one of the most common and practically non-treatable by standard methods. At present, the used drugs only maintain a state of temporary remission, simultaneously having a negative effect on various organs and structures and causing side effects.

At the same time, the experts have ignored more than 50 years of successful experience of low-level laser therapy, the results of hundreds of studies proving the effectiveness of the method in treating patients with all forms of bronchial asthma. It is proved that therapeutic and periodic (2-4 per year) courses of low-level laser therapy can significantly …

2020-03-28_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., with COVID-19 results included as of 10 a.m.

Note on cumulative counts: This report is provisional and subject to change. As public health investigations of individual cases continue, there will be corrections to the status and details of referred cases that result in changes to this report.
Note on the deaths: Deaths must be reported by health care providers, medical examiners/coroners, and recorded by local health departments …

Use Of Virtual Communication During Level Ii Fieldwork: A Personal Experience, Laronda Lockhart-Keene, Otd, Otr/L, Cla, Emily Spinelli, Cota/L

Department of Occupational Therapy Posters and Presentations

In fieldwork sites where no full time OTP is employed, a fieldwork student requires 8 hours a week of onsite supervision from an OTP. An onsite supervisor of another profession must be available while the OTP is offsite. The other professional is unable to answer questions related directly to occupational therapy (OT) practice. This poster describes virtual communication methods used during a level II fieldwork at a community based wellness program for older adults and how these methods translate to OT/OTA supervision in practice.

On The Inadequacy Of Species Distribution Models For Modelling The Spread Of Sars-Cov-2: Response To Araújo And Naimi, Joseph D. Chipperfield, Blas M. Benito, Robert B. O'Hara, Richard J. Telford, Colin J. Carlson

United States Public Health Resources

The ongoing pandemic of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing significant damage to public health and economic livelihoods, and is putting significant strains on healthcare services globally. This unfolding emergency has prompted the preparation and dissemination of the article “Spread of SARS-CoV-2 Coronavirus likely to be constrained by climate” by Araújo and Naimi (2020). The authors present the results of an ensemble forecast made from a suite of species distribution models (SDMs), where they attempt to predict the suitability of the climate for the spread of SARS-CoV-2 over the coming months. They argue that climate is …

Feminist Pedagogy In A Time Of Coronavirus Pandemic, Alexandra Juhasz, Laura Wexler, Liz Losh, Sharon Irish

Publications and Research

FemTechNet, a network of scholars, artists, and students working on, with, and at the borders of technology, science, and feminism, has a great deal of experience thinking about pedagogy and technology. We have produced real intimacy, vibrant classes, and insurgent pedagogy since 2012. The principles of our signature Distributed Open Collaborative Courses (DOCCs) are crucial (see below). In this time of crisis, we believe we need to think again, drawing the most power possible from the radical knowledges, tactics, and commitments of feminist pedagogies of past experience. We write while schools, colleges, and universities have closed in a cascade of …

Clinical Characteristics Of Patients Classified As Very High Risk And Not Very High Risk Based On The 2018 Aha/Acc Multi-Society Cholesterol Guideline, Aparna Sajja, Amir Ali, Hsin-Fang Li, Kateri Spinelli, Salim S. Virani, Seth Shay Martin, Tyler J Gluckman

Articles, Abstracts, and Reports

Background

The 2018 AHA/ACC Cholesterol Guideline recommendation to classify ASCVD patients as very high-risk (VHR) vs not-VHR (NVHR) has important implications for ezetimibe and PCSK9 inhibitor eligibility. We aimed to define the clinical characteristics of these two groups within a large multi-state healthcare system in the Western U.S.

Methods

We performed a retrospective cohort analysis of patients defined as having ASCVD in 2018 using EHR ICD-10 codes. VHR was defined by ≥2 major ASCVD events (ACS ≤12 months, history of MI >12 months, ischemic stroke, or symptomatic PAD) or 1 major ASCVD event and ≥2 high-risk conditions (age ≥65, DM, …

The Use Of Intra-Arterial Vancomycin In Splenic Artery Embolization To Decrease Post-Procedural Infections, Darby Shuler, Jeffrey Bodner, Ricardo Yamada, Marcelo Guimaraes, Heather Collins, Claudio Schonholz, D Thor Johnson, Christopher Hannegan

Radiology

To determine efficacy of vancomycin administration into the splenic artery immediately prior to embolization in decreasing the rate of post-procedural splenic abscess formation.

Adolescents’ Perceptions Of Contraception Access Through Pharmacies, Ashley H. Meredith, Emily Vahary, Tracey A. Wilkinson, Carolyn G. Meagher, Thomas Vielott, Mary A. Ott

Department of Pharmacy Practice Faculty Publications

Adolescent pregnancy is an important public health issue, and pharmacist prescribing has the potential to expand contraceptive access and decrease unintended pregnancy. However, little is known about acceptability and uptake of pharmacist prescribing among adolescents, particularly among youth in socially and politically conservative regions of the country. The study objective was to identify how young women in Indiana perceive pharmacist contraceptive prescribing. Participants were recruited from clinics and completed a simulated pharmacist contraception-prescribing encounter; a demographic and behavioral questionnaire; and an in-depth qualitative interview focused on adolescent perspectives on pharmacist prescribing. Data were analyzed using thematic analysis. Sixty young women …

A Novel Elvitegravir Nanoformulation For Drug Delivery Across The Blood-Brain Barrier To Suppress Hiv-1 In Macrophages And Microglia, Yuqing Gong

Theses and Dissertations (ETD)

Over the last two decades, the use of antiretroviral therapy (ART) has remarkably decreased the morbidity associated with HIV-1 infection. However, the prevalence of HIV-1-associated neurocognitive disorders (HAND) is still increasing. The appearance and persistence of HAND are partially due to the entry of HIV-1-infected monocytes into the brain. Within the central nervous system (CNS), HIV-1-infected macrophages and microglia serve as the major viral reservoirs and provide active viral replication even when systemic viral suppression has been achieved by ART. Efficient viral suppression of CNS macrophages and microglia is important for an effective HIV-1 treatment in the brain. The primary …

A Case Of Pacemaker Syndrome Mimicking A Heart Failure Exacerbation, Seline Haci, Som Aftabizadeh, Senthil Thambidorai, Karan Gupta, Ahsan Khan, Aman Patel, Kimberly Wilson, Anand Subramanian

Cardiology

No abstract provided.

Impact Of Indian Demonetization On Working And Non-Working Married Women: An Interpretative Phenomenological Analysis, Naved Iqbal, Imtiyaz A. Dar, Irum Khan

The Qualitative Report

The sudden announcement of demonetization in India caused an immediate financial crisis that cascaded throughout the whole country and consequently caused suffering in the lives of many people, one such group being married women. Therefore, the present study aimed to explore and understand how married women were impacted by the demonetization policy. A total of 20 working and non-working women were selected from New Delhi and a qualitative research design based on interpretative phenomenological analysis (IPA) was employed. The present study identified three themes (i.e., problems due to demonetization, coping with demonetization, and diverse experiences associated with hidden money) and …

Social Comparison Features In Physical Activity Promotion Apps: Scoping Meta-Review., Danielle Arigo, Megan M Brown, Kristen Pasko, Jerry Suls

College of Science & Mathematics Departmental Research

BACKGROUND: Smartphone apps promoting physical activity (PA) are abundant, but few produce substantial and sustained behavior change. Although many PA apps purport to induce users to compare themselves with others (by invoking social comparison processes), improvements in PA and other health behaviors are inconsistent. Existing literature suggests that social comparison may motivate PA for some people under some circumstances. However, 2 aspects of work that apply social comparison theory to PA apps remain unclear: (1) how comparison processes have been operationalized or harnessed in existing PA apps and (2) whether incorporating sources of variability in response to comparison have been …

Disruption In Murine Eml1 Perturbs Retinal Lamination During Early Development., Gayle B. Collin, J Won, Mark P. Krebs, W J Hicks, Jeremy R. Charette, Juergen K. Naggert, Patsy M. Nishina

Faculty Research 2020

During mammalian development, establishing functional neural networks in stratified tissues of the mammalian central nervous system depends upon the proper migration and positioning of neurons, a process known as lamination. In particular, the pseudostratified neuroepithelia of the retina and cerebrocortical ventricular zones provide a platform for progenitor cell proliferation and migration. Lamination defects in these tissues lead to mispositioned neurons, disrupted neuronal connections, and abnormal function. The molecular mechanisms necessary for proper lamination in these tissues are incompletely understood. Here, we identified a nonsense mutation in the Eml1 gene in a novel murine model, tvrm360, displaying subcortical heterotopia, hydrocephalus and …

2020-03-27_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., with COVID-19 results included as of 10 a.m.

Note on cumulative counts: This report is provisional and subject to change. As public health investigations of individual cases continue, there will be corrections to the status and details of referred cases that result in changes to this report.
Note on the deaths: Deaths must be reported by health care providers, medical examiners/coroners, and recorded by local health departments …

Covid-19 Newsletter (Vol. 2), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Investigation Into The Reproducibility Of The Association Of Cord Blood Magnesium Concentration And Cerebral Palsy Or Death In Children, Christopher Luke Dixon, Xiaoxi Liu, Alfred Balch, Maged Costantine, Catherine M. Sherwin

Pediatrics Faculty Publications

Objective: To evaluate the association of cord blood magnesium concentrations at the time of birth with cerebral palsy (CP) and neonatal death. Study Design: A secondary analysis of a randomized controlled trial that randomized women at imminent risk of delivery between 24 and 31 weeks of gestation to receive magnesium sulfate or placebo. This ‘study’s primary outcome was a composite of either moderate to severe CP or death. Secondary outcomes included CP, moderate to severe CP, neonatal death, and neonatal head ultrasound findings. We used a logistic regression model to evaluate the relationship between the concentration of magnesium in cord …

College Of Public Health News, Georgia Southern University

College of Public Health: News & Publications

• Georgia Southern faculty experts: Turn your COVID-19 panic into a plan

2020-03-27 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

Testing A Key Assumption Of Using Drones As Frightening Devices: Do Birds Perceive Drones As Risky?, Conor C. Egan, Bradley Blackwell, Esteban Fernández-Juricic, Page E. Klug

United States Department of Agriculture Wildlife Services: Staff Publications

Wildlife managers have recently suggested the use of unmanned aircraft systems or drones as nonlethal hazing tools to deter birds from areas of human-wildlife conflict. However, it remains unclear if birds perceive common drone platforms as threatening. Based on field studies assessing behavioral and physiological responses, it is generally assumed that birds perceive less risk from drones than from predators. However, studies controlling for multiple confounding effects have not been conducted. Our goal was to establish the degree to which the perception of risk by birds would vary between common drone platforms relative to a predator model when flown at …

Nr2f1 Heterozygous Knockout Mice Recapitulate Neurological Phenotypes Of Bosch-Boonstra-Schaaf Optic Atrophy Syndrome And Show Impaired Hippocampal Synaptic Plasticity, Chun-An Chen, Wei Wang, Steen E Pedersen, Ayush Raman, Michelle L Seymour, Fernanda R Ruiz, Anping Xia, Meike E Van Der Heijden, Li Wang, Jiani Yin, Joanna Lopez, Megan E Rech, Richard A Lewis, Samuel M Wu, Zhandong Liu, Fred A Pereira, Robia G Pautler, Huda Y Zoghbi, Christian P Schaaf

Faculty, Staff and Students Publications

Bosch-Boonstra-Schaaf optic atrophy syndrome (BBSOAS) has been identified as an autosomal-dominant disorder characterized by a complex neurological phenotype, with high prevalence of intellectual disability and optic nerve atrophy/hypoplasia. The syndrome is caused by loss-of-function mutations in NR2F1, which encodes a highly conserved nuclear receptor that serves as a transcriptional regulator. Previous investigations to understand the protein's role in neurodevelopment have mostly used mouse models with constitutive and tissue-specific homozygous knockout of Nr2f1. In order to represent the human disease more accurately, which is caused by heterozygous NR2F1 mutations, we investigated a heterozygous knockout mouse model and found that this model …

Operation Education: Going Out Of The Comfort Zone And Diving In To New Horizons, Amy Wojcik Rn

Patient Care Services / Nursing

No abstract provided.

Correspondence Re: Covid-19, Wku Board Of Regents

Board of Regents Documents

Letter from WKU Board of Regents to WKU faculty & staff thanking them for professionalism under strain of COVID-19 restrictions.

Maternal Depressive Symptoms Predict General Liability In Child Psychopathology, Danielle A. Swales, Hannah R. Snyder, Benjamin L. Hankin, Curt A. Sandman, Laura M. Glynn, Elyssia Poggi Davis

Psychology Faculty Articles and Research

Objective: The current study examines how maternal depressive symptoms relate to child psychopathology when structured via the latent bifactor model of psychopathology, a new organizational structure of psychopathological symptoms consisting of a general common psychopathology factor (p-factor) and internalizing- and externalizing-specific risk.

Method: Maternal report of depressive symptoms (Beck Depression Inventory – II) and child psychopathological symptoms (Child Behavior Checklist and Children’s Behavior Questionnaire) were provided by 554 mother-child pairs. Children in the sample were 7.7 years old on average (SD = 1.35, range = 5–11 years), and were 49.8% female, 46% Latinx, and 67% …

Mass Spectrometry Discovery-Based Proteomics To Examine Anti-Aging Effects Of The Nutraceutical Nt-020 In Rat Serum, Samantha M. Portis

USF Tampa Graduate Theses and Dissertations

Aging is a complex physiological process that leads to the deterioration of all cells and tissues throughout the body. Aging is a major risk factor for the onset of many degenerative diseases in both the central nervous system (CNS) and the periphery, but even nonpathological aging (“normal” aging) is associated with chronic inflammation, oxidative stress, and decreased stem cell proliferation and regenerative capacity. This decreased regenerative capacity in stem cell niches is thought to be a key component underlying the aging process and many disease states associated with aging.

While the exact biological mechanisms underlying impaired stem cell proliferation and …

Ten Years Risk Assessment Of Atherosclerotic Cardiovascular Disease Using Astro-Charm And Pooled Cohort Equation In A South Asian Sub-Population, Tariq Ashraf, Muhammad Naeem Mengal, Atif Sher Muhammad, Asal Khan Tareen, Nauman Khan, Khawar Abbas Kazmi, Asif Nadeem, Shakil Sarwar, Zara Bashir, Nadeem Qamar, Musa Karim

Medical College Documents

Background: Atherosclerotic cardiovascular diseases (ASCVD) are on the rise in low and middle-income countries attributed to modern sedentary lifestyle and dietary habits. This has led to the need of assessment of the burden of at-risk population so that prevention measures can be developed. The objective of this study was to assess ten years risk assessment of ASCVD using Astro-CHARM and Pooled Cohort Equation (PCE) in a South Asian sub-population.
Methods: A total of 386 residents of all six districts of Karachi with no ASCVD were enrolled in the study through an exponential non-discriminative referral snowball sampling technique. The inclusion criteria …