Medicine and Health Sciences Commons^™

2020-04-09 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

Arid1a Haploinsufficiency Initiates Neural Crest Transformation In A Mouse Model Of Mycn-Driven Neuroblastoma, Kirby A. Wallace

Theses and Dissertations (ETD)

Mouse models of cancer are critical for developing therapeutic treatments for pediatric patients. Recent sequencing studies of neuroblastoma (NBL) patient tumors have uncovered precise deletions in the chromatin remodeler and tumor suppressor gene (TSG) ARID1A. Additional causal studies supported ARID1A’s candidacy as a putative 1p36 TSG in MYCN-driven NBL. This study aimed to causally test Arid1a loss during Mycn-driven NBL initiation through the development of a mouse model of high risk NBL.In this study, we modified a Mycn-driven mouse model of NBL to incorporate Cre mediated deletion of floxed Arid1a. Briefly, in freshly isolated embryonic day 9.5 primary trunk neural …

Human Papillomavirus (Hpv) Vaccine Knowledge, Awareness And Acceptance Among Dental Students And Post-Graduate Dental Residents, Steve Kent Mann, Karl Kingsley

Dental Medicine Faculty Research

Introduction: The recent development of a vaccine that is highly effective against the human papillomavirus (HPV) has been met with widespread clinical and public health professional acceptance. However, social and societal barriers to vaccination may hamper public health efforts to prevent HPV-mediated diseases. Although a few studies have evaluated knowledge or awareness of HPV vaccination among dentists or dental educators, few studies have evaluated the acceptance, knowledge and awareness of HPV vaccination among dental students and post-graduate dental residents. The primary goal of this study is to evaluate survey responses regarding acceptance, knowledge and awareness of HPV vaccination among dental …

L’Utilizzo Del Tourniquet Nelle Emorragie Da Trauma In Ambito Civile: Una Revisione Narrativa Della Letteratura (Tourniquet In Traumatic Haemorrhage In Civilian Settings: A Narrative Literature Review), Celeste Marie Alfes

Faculty Scholarship

Introduzione: L’emorragia arteriosa è una delle principali cause di morte in ambito civile e militare. Nonostante la pressione manual diretta del sito emorragico sia ancora lo standard di riferimento per il controllo del sanguinamento, l’applicazione precoce, in ambito extra-ospedaliero di tourniquet si è dimostrata capace di ridurre le morti con bassi rischi di complicanze. L’obiettivo dello studio è quello di sintetizzare i metodi di utilizzo, le condizioni dei pazienti, gli esiti e le complicazioni relative alle applicazioni del tourniquet. Materiali e Metodi: È stata condotta una revisione narrativa della letteratura tramite PubMed. Risultati: Dieci articoli inclusi hanno fornito informazioni su …

Music And Exercise On Brain With Dementia, Claudio Otero Iii

Student Scholar Showcase

No abstract provided.

Tetralogy Of Fallot: A Clinical Review, Jacob Wooten, Joshua Bahos Silva

Student Scholar Showcase

Tetralogy of Fallot is a congenital heart disease that is associated with structural abnormalities during fetal development 1. The incidence of Tetralogy of Fallot in the United States is approximately 3-5 cases per 10,000 live births and is considered one of the most common cyanotic congenital heart diseases 2. The exact etiology of Tetralogy of Fallot is unknown, however it is thought to be associated with untreated maternal diabetes, maternal use of retinoids, as well as chromosomal abnormalities 2. The main components of this disease state include a right ventricular outflow obstruction, interventricular communication in the form of a ventricular …

Acoustic Changes During Passage Reading In Speakers With Parkinson's Disease, Kimberly C. Grubbs

LSU Master's Theses

Purpose: The purpose of this study was to evaluate speech changes in Parkinson’s disease (PD) while reading a passage, using both local (i.e., segment level) and global (i.e., utterance level) acoustic measures.

Methods: 20 speakers participated in the study (10 PD, 10 neurologically healthy controls). The speakers were asked to read The Caterpillar passage in a conversational mode. A total of five acoustic measures were included (local: vowel duration, Euclidean distance between corner vowels and schwa; global: articulation rate, F0/intensity range). These acoustic measures were compared between two sentences located in the two positions within the paragraph, initial and final. …

The Relationship Between The Development Of Communicative Functions In Children With Autism Spectrum Disorders, Isabelle Bankston

LSU Master's Theses

In regard to the assessment of language, it is difficult to determine exact communicative functions that are exhibited early in development that could indicate a prognostic value of verbal abilities and outcomes of children with autism spectrum disorder (ASD). The Verbal Behavioral Milestones Assessment and Placement Program (VB-MAPP, Sundberg, 2008) is frequently used in Applied Behavior Analysis for standard assessment procedures to measure development over time. The current study was designed to use the VB-MAPP to determine a relationship between certain communicative functions (i.e., mand, tact, listener responding, echoic, and intraverbal) that may suggest a correlation in growth in each …

Tradition, Rachel Gist

Reflections, Poetry, Photos, and other Writings

I wrote in hope that people could relate to the feelings I had during this time. Having Taylor time cut short is hard but also helped me to reflect and be even more grateful.

2020-04-08_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was captured from the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_99207---,00.html.

The website contained the table Count of Confirmed COVID-19 Cases by Date of Onset , sorted by Michigan Preparedness Region. It also contained 18 charts, including the count of confirmed Covid-19 cases by date of onset in the state overall as well as in each preparedness region,and the normalized rate of Covid-19 cases per 1,000,000 residents in both the state and in each preparedness region.

Copd Exacerbation Caused By Sars-Cov-2: A Case Report From The Louisville Covid-19 Surveillance Program, Forest W. Arnold, Kamran Mahmood, Angeline Prabhu, Darmaan Aden, Anupama Raghuram, Mark Burns, Leslie A. Beavin, Donghoon Chung, Kenneth E. Palmer, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

A 53-year-old male with a history of chronic obstructive pulmonary disease (COPD) on home oxygen presented to the hospital with worsening shortness of breath plus cough. He was admitted to the intensive care unit for COPD exacerbation and respiratory failure. A routine evaluation was performed, including a nasopharyngeal swab for a respiratory viral panel, which was negative. His symptoms improved over 48 hours, after which time a surveillance test for SARS-CoV-2 returned as positive. After clinical improvement, he was discharged to home isolation.

How To Prevent Covid-19 In Nurses And Physicians In The Hospital Setting: Universal Test-And-Isolate For All Patients Admitted To Hospitals, Julio A. Ramirez, Ruth Carrico, Forest W. Arnold, Paul Schulz

The University of Louisville Journal of Respiratory Infections

No abstract provided.

New Campus Health And Safety Measures, April 8, 2020, University Of Northern Iowa

UNI Response to COVID-19

A memo staring that most campus buildings will be locked from April 10 until further notice, with further information for those employees that continue to come to campus.

2020-04-08_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places.
It contains aggregated data, self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Ua94/6/1 My Story: Wku Baseball's Ray Zuberer Iii, Ray Zuberer Iii

Student/Alumni Personal Papers

My Story is a series of first-person feature articles written by WKU student-athletes. The student-athletes will be telling their own stories in their own words. This article written by baseball senior outfielder Ray Zuberer III, whose season came to a sudden end as the team was heading to Birmingham, Alabama for its first conference series of the year.

#Selfcare: Perspectives From Instagram, Luke Nguyen, Colin Mullis, Bailey Rydzewski, Julie Williams Merten Phd

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Background: While widely-used by clinicians, self-care has recently emerged as a trending term in mainstream and social media. Informal health and support communities have formed on social media sites such as Instagram, which hosts more than one billion monthly users and ranks as the second most popular social networking application in the United States.

Purpose: This study investigated how the term self-care is portrayed on Instagram. In particular, the researchers examined how self-care was depicted across the six dimensions of wellness and four established self-care themes including illness prevention, management of chronic illness, promotion of optimal health, and early detection …

2020-04-08 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Sammy Anyona, Shawn Stoicu, Anastasiya Nestsiarovich, Praveen Kumar, Hannah Groves, Danielle Rivera, Estefania Montanez, Rachel D. King, Andrew S. Rowland, Tudor I. Oprea, Orrin Myers, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

Call for all UNMH healthcare workers to wear masks. Navajo Nation curfew. Congress introduces $250B local aid legislation. State cash stimulus for self-employed. Domestic travel curtailment. Measles threat looms as vaccinations paused. UK expanding hospital sites. African Americans worse risk of infection and death. 40k healthcare worker hydroxychloroquine trial. Employment woes for early career US and foreign scientists. Measles threat looms. UK makeshift hospital expansion. African Americans more vulnerable to SARS-CoV-2. Large prophylactic hydroxychloroquine trials for healthcare workers. New CDC and WHO face covering guidelines. UK NICE guidance: Paracetamol, not NSAIDs for managing COVID-19 fever. Large review of …

Celebrities In Rehab: Who Is More At Risk?, Skye Downey, Anastasia Kuhles, Beth Kulikov, Vanessa Martinez, Karl Schneider, Sydney Weinreb, Tes Tuason Phd

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Does celebrity status make people more likely to need rehab? The purpose of the current study is to better understand the trends in substance abuse rehabilitation admittance among celebrities from 2005 to 2020. The authors became interested in the topic due to its myriad implications within the clinical mental health counseling field. Popular lore indicates a positive correlation between celebrity status and substance abuse. Previous studies have covered the predictive factors of celebrity downfall, but few have gone into specific trends among rehabilitation admittance. This mixed method review is designed to further look at the specific factors in celebrity status …

The Relationship Between The Use Of Hormonal Contraceptives And Ligamentous Knee Injury In The Female Collegiate Athlete, Nicole Michelle Thompson

Theses and Dissertations

Female athletes are three to six times more likely than males to sustain a ligamentous knee injury due to hormonal risk factors. Hormones of the menstrual cycle have been shown to alter the physiological component of ligamentous structures during the three phases of the cycle. Use of hormonal contraceptives (HCs) may influence the incidence and severity of ligamentous knee injuries in female athletes. The objective of this cross-sectional study was to determine the relationship between HC use and the type and severity of ligamentous knee injuries sustained among female collegiate athletes using an online survey distributed to NCAA female athletes …

2020-04-08_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., with COVID-19 results included as of 10 a.m.

Note on cumulative counts: This report is provisional and subject to change. As public health investigations of individual cases continue, there will be corrections to the status and details of referred cases that result in changes to this report.
Note on the deaths: Deaths must be reported by health care providers, medical examiners/coroners, and recorded by local health departments …

Temporary Hiatus Of Panther Caucus, April 8, 2020, University Of Northern Iowa

UNI Response to COVID-19

An announcement that the emails providing weekly updates on issues from the state legislature concerning UNI have been suspended until the legislature comes back into session.

Research Data Management From The Stem Perspective: Reproducibility, Data Reuse, Data Integration, Melissa D. Clarkson

Institute for Biomedical Informatics Presentations

This presentation highlights three big ideas in STEM data management:

• Reproducibility requires scripted pipelines
• Data reuse requires metadata and documentation
• Data integration requires use of standards

It also provides an overview of the FAIR principles for research data management.

Potential Predictors Of Nodal Metastasis In Early Tongue Cancer Found Through Aperio Image Analysis, Robin Pupo, Neda Qosja, Mohammad Tehseen, Omer Farooq, Arif Jamshaid, Fatima Rehman

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Introduction: Excessive use of cigarettes cigars/ pipe as well as smokeless tobacco is one of the most common cause of oral cancer. In Shaukat Khanum Memorial Center Hospital and Research Center (SKMCH&RC) in Pakistan, Squamous Cell Carcinoma of Tongue (SCCOT) is the second most common head and neck malignancy. Approximately 20-30% of patients with early oral tongue carcinoma will have occult neck nodal modal metastasis. Presently, elective neck dissection remains the only reliable way to predict regional and or distant metastasis. There is a pressing need to find reliable biomarkers and non-invasive predictors of metastasis and patient response in early …

An Overview Of The Rd Mentorship Program, Mia Howell, Lora Chizmar, Karen Beathard, Kristen Hicks-Roof Phd

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

The Academy of Nutrition and Dietetics highlights the need for more mentorship opportunities for Registered Dietitian (RDs) in their 2017 Strategic Plan. There are a limited number of published structured programs that facilitate relationships between practicing dietitians and dietetics students (DS). The purpose of the RD Mentorship Program is to determine the impact of a project-based mentoring experience on self-perceptions of mentoring and professional advancement. The RD Mentorship Program partners RDs with DS to work on specific nutrition-related projects. Partnerships are required to meet at least once per month to work on their project. After piloting the program for several …

What Makes An International Student In The U.S. Have Less Psychological Distress?: Secrets Of Adjustment, Bridget R. Stanton, Kristen Calleja Salerno Phd, Tes Tuason Phd

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

This comparative research studied psychological distress, symptomatology, depression, and anxiety in two groups of college students, those who relocated from a different country and those who reside in a southeastern state in the United States. It aims to investigate the differences in levels of distress depending on whether or not students had relocated from a different country. Fifty-one international students and 95 U.S. students completed questionnaires, which examined psychological distress, stress, socio-economic status (SES), and acculturation to culture of origin and U.S. culture. Unexpectedly, international students did not have significantly different levels of psychological distress from U.S. students. In terms …

Common Gba Variants In Parkinson's Disease And Lewy Body Dementia Patients, Megan T. Mazak, Alexandra I. Soto Ms, Zbidniew K. Wszolek, Md, Dennis W. Dickson Md, Owen A. Ross Phd

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Parkinson’s disease (PD) and Lewy Body Dementias (LBD) are two distinct synucleinopathies with a great amount of symptomatic and genetic overlap. This overlap can often lead to misdiagnosis. Misdiagnosis can result in improper therapy and therefore a poorer prognosis. LBD is a neuropath diagnosis with subcategories, but for the purpose of this project we discuss LBD as a whole. GBA is a gene common to both diseases with different effect sizes in each, although increasing severity of disease for both. Common is defined as a presence greater than 1% in healthy controls. GBA is found in 2-37% of Parkinson cases …

Cancer Risk Perception Predictors For Total Body Skin Examinations: A Cross-Sectional Study Using Hints 2017 Data, Meghann Wheeler, Hanadi Hamadi Phd, Julie Williams Merten Phd

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Background: Despite the lack of national skin cancer screening recommendations, a total body skin examination by a healthcare provider may detect skin cancer earlier allowing for more effective treatment and better outcomes.

Objective: Examine prevalence, demographic, and cancer risk perceptions of adults who have had a skin examination performed by a healthcare provider.

Methods: Retrospective, cross-sectional analysis of a nationally representative sample of U.S. adults using the Health Information National Trends Survey (HINTS). Logistic regressions were performed to identify associations between having a skin examination, risk perceptions, and demographic variables.

Results: Approximately 46% of the sample reported having a skin …

Feline-Human Zoonoses Transmission In North Africa: A Systematic Review, Breck Peterson

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Throughout human history, domestic animal species have represented a unique zoonotic disease risk for the transmission of pathogens ranging from viral, bacterial, parasitic, and fungal. In North Africa, cats have a particularly long record and occupy a specialized niche within many communities. This systematic review was conducted to analyze the current and historical literature documenting the breadth and variety of zoonoses in North Africa, specifically relating to the domesticated feline. Multiple electronic databases were searched on January 16, 2019 for published reports on feline zoonoses in North Africa. A total of 76 studies met the inclusion criteria for a full …

Association Between Exposure To Polycyclic Aromatic Hydrocarbons And Stroke Among Adults In The United States, Breck Peterson

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

Background: Polycyclic aromatic hydrocarbons (PAHs) are environmental pollutants released through multiple processes including manufacturing, automotive emissions, and tobacco smoking. Previous evidence has shown that exposure to PAHs is associated with diabetes, cardiovascular disease, and cancer, but the association with stroke has not specifically been examined.

Methods: The study used cross-sectional data from the 2005 to 2014 National Health and Nutrition Examination Survey (NHANES) for 8,650 subjects. Multivariable logistic regression was utilized to investigate the association between exposure to PAHs and an outcome of stroke. The exposure distribution for each PAH was divided into quintiles with the lowest level of exposure …

Favorite Teacher Or Worst Nightmare? Teachers Who Crossed The Line, Marybeth Borreca, Matthew Brewer, Heather Brinker, Alison Leapley-Williams, Anastasia Pederson, Kourtney Sellers, Tes Tuason

Showcase of Osprey Advancements in Research and Scholarship (SOARS)

What kind of teacher sexually abuses her students? The current study, guided by critical theory, examines common characteristics of female high school teachers who sexually abuse their students. Extant research on teacher student relationships have found commonalities in the demographics of the offenders, their experience of adverse childhood experiences, common age of the victims, re-offense rates, and public perception of these types of crimes. The current study furthers previous research, by investigating their marital status at the time of the offense (married or not married), whether or not the offender has children, and school type (public or private). This study …