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Articles 15061 - 15090 of 325144

Full-Text Articles in Medicine and Health Sciences

Variety Of Study Methods In Ophthalmology Residency, Muhammad Rizqy Abdullah, Evelyn Komaratih Dec 2025

Variety Of Study Methods In Ophthalmology Residency, Muhammad Rizqy Abdullah, Evelyn Komaratih

Folia Medica Indonesiana

Effective study methods are critical in ophthalmology residency, which must balance cognitive learning with surgical skill development. This systematic review examined non-surgical cognitive strategies and surgical training techniques to inform curriculum design and enhance resident performance. A structured literature search was conducted in PubMed and Scopus (2016–2025) using keywords (“study method” OR “effective study” OR “learning strategy” OR “educational intervention” OR “training approach”) AND (“ophthalmology residency” OR “resident education”). After screening and applying eligibility criteria, 17 studies were included. Methods were categorized as non-surgical (n = 5) and surgical learning (n = 12). This review revealed that non-surgical strategies, including …


Exploring Ethanol Extract Of Kersen Fruit (Muntingia Calabura L) As Antimicrobial And Antibiofilm, Hafidz Firmanda, Agung Dwi Wahyu Widodo, Manik Retno Wahyunitisari Dec 2025

Exploring Ethanol Extract Of Kersen Fruit (Muntingia Calabura L) As Antimicrobial And Antibiofilm, Hafidz Firmanda, Agung Dwi Wahyu Widodo, Manik Retno Wahyunitisari

Folia Medica Indonesiana

Infections caused by microbial biofilms pose a clinical treat in terms of patient morbidity and mortality rates. For potential treatment this study aims to determine antimicrobial and antibiofilm activity of kersen fruit extract (Muntingia calabura L) on Staphylococcus aureus, Escherichia coli, and Candida albicans. This research used true experimental method with posttest only control group design. Using 6 kersen fruit extract concentration and 4 replications. Antimicrobial test used tube dilution method and antibiofilm test used two different scenario, biofilm growth inhibition test and biofilm degradation test. MIC result against Staphylococcus aures and Escherichia coli at extract …


Pathological And Molecular Parameters Show No Significant Association With Residual Cancer Burden In Breast Carcinoma, Fishella Aprista Rahmanti, Willy Sandhika, Lusiani Tjandra Dec 2025

Pathological And Molecular Parameters Show No Significant Association With Residual Cancer Burden In Breast Carcinoma, Fishella Aprista Rahmanti, Willy Sandhika, Lusiani Tjandra

Folia Medica Indonesiana

Residual Cancer Burden (RCB) is a validated scoring system that quantifies the amount of tumour remaining after neoadjuvant chemotherapy (NAC) for breast cancer, providing prognostic information beyond binary outcomes, such as pathologic complete response (pCR). pCR represents a binary endpoint within various NAC response-grading systems, including RCB, rather than a separate reporting system. This study aimed to assess clinicopathological and molecular predictors of RCB class, including histological grade, histopathological type, molecular subtype, and Ki-67 index. A retrospective study was conducted on 68 patients diagnosed with breast carcinoma who underwent NAC. Descriptive statistics and Pearson, Spearman, and chi-square tests were used …


Group Counseling Deactivation Mode To Improve Psychological Well-Being Of Students, Muya Barida, Dian Ari Widyastuti, Yuanita Dwi Krisphianti, Aslina Ahmad, Nurul Hidayati Rofiah, Andriyani Andriyani, Riana Mashar, Emiko Saraswaty Dec 2025

Group Counseling Deactivation Mode To Improve Psychological Well-Being Of Students, Muya Barida, Dian Ari Widyastuti, Yuanita Dwi Krisphianti, Aslina Ahmad, Nurul Hidayati Rofiah, Andriyani Andriyani, Riana Mashar, Emiko Saraswaty

Jurnal Kajian Bimbingan dan Konseling

Life moves dynamically, profoundly impacting adolescents and often causing deep anxiety due to numerous pressures. The gap between expectations and reality frequently exacerbates this anxiety. Ideally, adolescents should be equipped to manage their inner lives to prevent excessive anxiety, and individuals can better manage anxiety if they possess strong psychological well-being. This study aims to improve psychological well-being through a group counseling deactivation mode. The research applied an experimental research method with a one group pretest-posttest design. Participants consisting of junior high school students in Yogyakarta, selected through purposive sampling for their low psychological well-being levels. Data on psychological well-being …


Online Counseling In Improving Achievement Motivation Over The Last Decade: A Bibliometric Review, Shopyan Jepri Kurniawan, Bambang Dibyo Wiyono, Mohd. Aziz Zulazmi Dec 2025

Online Counseling In Improving Achievement Motivation Over The Last Decade: A Bibliometric Review, Shopyan Jepri Kurniawan, Bambang Dibyo Wiyono, Mohd. Aziz Zulazmi

Jurnal Kajian Bimbingan dan Konseling

This research aims to determine online counseling research trends to increase achievement motivation. The method used in this research is bibliometric analysis using VOSviewer. The data used is the Scopus database for the last 10 years. Research findings found that there were 4302 documents that met the specified criteria. The number of online counseling studies increased gradually over the 2013-2022 research period. The largest source of documents comes from 3691 articles. Meanwhile, the annual distribution of 100 or more citations will be the highest in 2022 with 16. The keyword ``achievement motivation'' is not included in the top 10 keywords, …


Development And Evaluation Of The Agitation In Alzheimer's Screener For Caregivers (Aasc): A Clinical Tool To Screen For Agitation., Carolyn Clevenger, W Clay Jackson, Jared Stroud, Malaak Brubaker, Mehul Patel, Iwona Bucior, Emily Bratlee-Whitaker, T Michelle Brown, Sheri Fehnel, Sue Peschin, Jeffrey Cummings, George Grossberg Dec 2025

Development And Evaluation Of The Agitation In Alzheimer's Screener For Caregivers (Aasc): A Clinical Tool To Screen For Agitation., Carolyn Clevenger, W Clay Jackson, Jared Stroud, Malaak Brubaker, Mehul Patel, Iwona Bucior, Emily Bratlee-Whitaker, T Michelle Brown, Sheri Fehnel, Sue Peschin, Jeffrey Cummings, George Grossberg

Ambulatory and Primary Care Articles

OBJECTIVE: Although agitation is a common neuropsychiatric symptom in Alzheimer's dementia, it can be challenging to recognize and diagnose. Caregivers of individuals with Alzheimer's dementia are often the first to encounter agitation behaviors but may struggle to recognize and communicate symptoms to healthcare professionals (HCPs). Here, we describe the development and evaluation of the Agitation in Alzheimer's Screener for Caregivers (AASC), a practical screening tool to identify agitation symptoms and facilitate caregiver-HCP communication.

METHODS: The AASC was developed based on the International Psychogeriatric Association (IPA) criteria for agitation in cognitive disorders, input from multidisciplinary experts, and qualitative interviews with caregivers …


Association Between Vitamin D And Cholesterol In Post-Acne Hypertrophic Scars And Keloids: A Cross-Sectional Study, Yuli Kurniawati, Yulia Farida Yahya, Sarah Diba, Rina Novriani, Hasbiallah Yusuf, Ekta Martgaredta Dec 2025

Association Between Vitamin D And Cholesterol In Post-Acne Hypertrophic Scars And Keloids: A Cross-Sectional Study, Yuli Kurniawati, Yulia Farida Yahya, Sarah Diba, Rina Novriani, Hasbiallah Yusuf, Ekta Martgaredta

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Post-acne hypertrophic scars and keloids result from abnormal wound healing within the pilosebaceous unit. Ruptured microcomedones create wounds that can lead to prolonged inflammation, increased collagen synthesis, and fibrinolysis inhibition, resulting in elevated scar tissue in acne lesions. Vitamin D deficiency can lead to prolonged inflammation and damage to dermal collagen. High total cholesterol levels can lead to excessive sebum production, exacerbating inflammation and fibrosis. This study aimed to determine the association between serum vitamin D and total cholesterol levels with scar severity in patients with post-acne hypertrophic scars and keloids.

Methods: This analytical cross-sectional study was conducted at …


Extensive Superficial Dermatomycosis Caused By Cladophialophora Sp., A Deep Mycosis Pathogen: A Case Report, Nikko Vanda Limantara, Agnes Sri Siswati, Flandiana Yogianti Dec 2025

Extensive Superficial Dermatomycosis Caused By Cladophialophora Sp., A Deep Mycosis Pathogen: A Case Report, Nikko Vanda Limantara, Agnes Sri Siswati, Flandiana Yogianti

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Superficial dermatomycosis, predominantly caused by dermatophytes, affects approximately 20–25% of the global population. However, non-dermatophytic fungi, such as Cladophialophora species (sp.), can also cause similar cutaneous infections. Although less common, these organisms are particularly concerning in immunocompromised individuals.

Case Illustration: A 66-year-old immunocompromised male presented with widespread pruritic and erythematous patches, initially misdiagnosed as tinea corporis. Despite receiving standard antifungal therapy, his condition persisted. Further investigation through fungal culture identified Cladophialophora sp., which was resistant to common antifungal agents such as fluconazole, itraconazole, and ketoconazole. However, the fungus was sensitive to terbinafine, which has …


The Efficacy Of Tranexamic Acid In Melasma: A Review, Ninda Sari, Rachmah Diana Putri, Syahriani Syahrir, Agustina Agustina, Mikyal Bulqiah Dec 2025

The Efficacy Of Tranexamic Acid In Melasma: A Review, Ninda Sari, Rachmah Diana Putri, Syahriani Syahrir, Agustina Agustina, Mikyal Bulqiah

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Melasma is a common acquired pigmentary condition presenting as dark macules or patches on sun-exposed areas of the face. Conventional treatments rely on topical bleaching agents and sun protection, while additional adjuvant options such as chemical peels, dermabrasion, and laser procedures are often applied. However, recurrence is frequent, and overall therapeutic success remains modest, significantly affecting patient quality of life. Recently, tranexamic acid (TXA) has gained attention as a novel therapeutic approach. This review provides an overview of the available evidence on the efficacy of TXA, used as monotherapy or in combination regimens, for the management of melasma. …


Successful Management Of Generalized Pustular Psoriasis With Cyclosporine In Hiv-Infected Patient, Rasinta Ayudya Deltania, Anggun Putri Yuniaswan Dec 2025

Successful Management Of Generalized Pustular Psoriasis With Cyclosporine In Hiv-Infected Patient, Rasinta Ayudya Deltania, Anggun Putri Yuniaswan

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Generalized pustular psoriasis (GPP) can be associated with human immunodeficiency virus (HIV) infection, making its management more challenging and complex. This case report aims to evaluate the effectiveness and safety of cyclosporine in HIV-associated GPP.

Case illustration: A 31-year-old male with a six-year history of HIV on antiretroviral therapy presented with rapidly spreading erythematous plaques with scaling and patches, along with “lakes of pus”, involving 50% of the body surface area (BSA). He reported oral burning, dysgeusia, and odynophagia; tongue Gram stain showed budding yeast and pseudohyphae. The patient was diagnosed with GPP and oral candidiasis in the setting …


Laser And Light-Based Therapy For Hair Growth And Hair Removal, Michelle Wiryadana, Nelva Karmila Jusuf Dec 2025

Laser And Light-Based Therapy For Hair Growth And Hair Removal, Michelle Wiryadana, Nelva Karmila Jusuf

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Recent advances in laser and light-based technologies have introduced new options for both the stimulation of hair growth for alopecia and the reduction of unwanted hair growth. However, the clinical evidence remains varied, and treatment outcomes are influenced by factors such as device type, wavelength, and individual response. Ongoing evaluation of safety, efficacy, and standardization of treatment parameters is therefore essential.

Discussion: This review provides an in-depth discussion of the principles, mechanisms, safety, and efficacy of lasers in promoting hair growth, as well as on lasers and light-based therapies used for hair removal. The mechanisms of laser-induced hair growth …


Evaluating The Impact Of A Community-Based Prostate Cancer Screening Program, Amy Leader, Kristine Pham, Nicola Cianci, Hannah Knapp, Fatuma Doka, Suzanne Barron, Oleksandr Kolesnikov, Jordan Dehoratius, Katie Bradley, Le'ann Robles, Robert Giamboy, Olivia Dahlgren, Leonard G. Gomella Dec 2025

Evaluating The Impact Of A Community-Based Prostate Cancer Screening Program, Amy Leader, Kristine Pham, Nicola Cianci, Hannah Knapp, Fatuma Doka, Suzanne Barron, Oleksandr Kolesnikov, Jordan Dehoratius, Katie Bradley, Le'ann Robles, Robert Giamboy, Olivia Dahlgren, Leonard G. Gomella

Kimmel Cancer Center Faculty Papers

BACKGROUND: One out of eight men in the U.S. will be diagnosed with prostate cancer during his lifetime. Black men are more likely to be diagnosed with and die from prostate cancer than other males, contributing to significant prostate cancer disparities. Early detection, often by routine screening, allows for more options for treatment and an increased chance of survival. Barriers to screening contribute to prostate cancer disparities, particularly among those who lack regular access to health care. Community based screening programs may overcome barriers to prostate cancer screening.

METHODS: An urban, NCI-designated cancer center collaborated with a national prostate cancer …


Video Education On The Knowledge Of Cosmetics And Skin Care Contact Dermatitis: A Cross-Sectional Study, Muhammad Rizkinanda Prasetyo, Damayanti Damayanti, Lilik Herawati, Sylvia Anggraeni Dec 2025

Video Education On The Knowledge Of Cosmetics And Skin Care Contact Dermatitis: A Cross-Sectional Study, Muhammad Rizkinanda Prasetyo, Damayanti Damayanti, Lilik Herawati, Sylvia Anggraeni

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Contact dermatitis is an immunologic reaction to irritants, allergens, and is commonly associated with cosmetics and skin-care products. Limited knowledge of this condition increases the risk of improper product use and delays preventive measures. Therefore, education plays a crucial role in fostering a comprehensive understanding of its etiology and prevention. This study aimed to evaluate the effectiveness of a video-based educational intervention in enhancing women’s knowledge regarding contact dermatitis related to cosmetics and skin-care products.

Methods: This cross-sectional study collected primary data from 100 female academics aged 17–45 at Airlangga University, Surabaya, East Java, Indonesia. Knowledge of contact dermatitis …


Difficulties In Diagnosing Primary Cutaneous Mucormycosis: Excluding Mycobacterium Other Than Tuberculosis, Chinda Liaska Indah, Sri Linuwih Susetyo Wardhani Menaldi, Sondang Pandjaitan Sirait, Sandra Widaty Dec 2025

Difficulties In Diagnosing Primary Cutaneous Mucormycosis: Excluding Mycobacterium Other Than Tuberculosis, Chinda Liaska Indah, Sri Linuwih Susetyo Wardhani Menaldi, Sondang Pandjaitan Sirait, Sandra Widaty

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Mucormycosis is a rare fungal infection caused by a group of opportunistic fungi from the class Zygomycetes. Primary cutaneous mucormycosis is the most common type of mucormycosis in immunocompetent patients. This study reported a case of primary cutaneous mucormycosis with nonspecific clinical characteristics and various supporting examinations. The patient was successfully treated with in toto excision and oral ketoconazole.

Case Illustration: A 40-year-old female presented with purplish-red spots and painless lumps on the second finger of her right hand, which had been present for a year. She had a history of frequent fish tank cleaning and gardening but …


The Profile Of Skin Cancer Patients At Dr Pirngadi Hospital Medan: A Retrospective Study, Febrina Dewi Pratiwi Lingga, Aisya Indira, Remenda Siregar Dec 2025

The Profile Of Skin Cancer Patients At Dr Pirngadi Hospital Medan: A Retrospective Study, Febrina Dewi Pratiwi Lingga, Aisya Indira, Remenda Siregar

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Skin cancer is among the most common malignancies, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and malignant melanoma. In Indonesia, it ranks third after cervical and breast cancer. This study aimed to analyze the demographic, clinical, and treatment patterns of skin cancer cases at Dr. Pirngadi General Hospital, Medan, Indonesia from 2019 to 2023.

Methods: A retrospective descriptive study was conducted using medical record data of all skin cancer patients treated from 2019 to 2023. Variables analyzed included age, sex, occupation, lesion site, skin cancer type, and treatment modality. Data were analyzed using univariate statistics and presented …


Effectiveness And Safety Of Moisturizing Wash And Cream In The Treatment Of Elderly Xerosis Cutis, Lili Legiawati, Shannaz Nadia Yusharyahya, Rinadewi Astriningrum, Fathirah Rahmatiah Puteri, Nabila Chalisya Ilyas Dec 2025

Effectiveness And Safety Of Moisturizing Wash And Cream In The Treatment Of Elderly Xerosis Cutis, Lili Legiawati, Shannaz Nadia Yusharyahya, Rinadewi Astriningrum, Fathirah Rahmatiah Puteri, Nabila Chalisya Ilyas

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: The skin undergoes degenerative and metabolic changes with aging, increasing susceptibility to dermatological conditions. Xerosis cutis, characterized by rough, scaly skin on the lower legs, is the most common cause of pruritus in elderly patients, with a prevalence of 38–85%. Treating xerosis cutis is challenging due to its multifactorial causes, especially in the elderly. Moisturizers remain the primary and most effective treatment, providing convenience and efficacy. This study aimed to evaluate the effects of QV Intensive Moisturizing Cleanser™️ and QV Intensive Cream™️ (Ego Pharmaceuticals, Australia), which contain humectants, emollients, and occlusives.

Case Illustration: This observational case series involved six …


The Recurrence Of Bowen’S Disease After Topical 5% 5-Fluorouracil Cream Application: A Systematic Review, Mohammad Agassi Antoniman, Ika Anggraini Dec 2025

The Recurrence Of Bowen’S Disease After Topical 5% 5-Fluorouracil Cream Application: A Systematic Review, Mohammad Agassi Antoniman, Ika Anggraini

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Bowen’s disease (BD) may develop into cutaneous squamous cell carcinoma (CSCC), which can spread to other parts of the body. 5% 5-fluorouracil (5-FU) cream is commonly used for topical therapy on BD; however, the frequency and duration of treatment per cycle have not been standardized. This systematic review aimed to identify the most effective frequency and duration of 5% 5-FU treatment for achieving complete clearance or minimal recurrence.

Methods: A literature search was conducted using three electronic databases (PROSPERO ID: CRD42024607488): MEDLINE, Cochrane, and Scopus. The articles were selected based on their relevance to the clinical question. Appraisals were …


Learning Engagement In Primary Education: Development And Validation Of A Contextualized Scale For Indonesian Elementary School Students, Meidias Abror Wicaksono, Edy Purwanto, Tri Joko Raharjo, Diani Akmalia Apsari, Bambang Subali, Nuni Widiarti Dec 2025

Learning Engagement In Primary Education: Development And Validation Of A Contextualized Scale For Indonesian Elementary School Students, Meidias Abror Wicaksono, Edy Purwanto, Tri Joko Raharjo, Diani Akmalia Apsari, Bambang Subali, Nuni Widiarti

Jurnal Kajian Bimbingan dan Konseling

This study aims to develop and examine the validity and reliability of a contextual learning engagement scale for elementary school students. The scale was develop based on the learning motivation and behavior theory by Schunk, Pintrich, and Meece, and interest dimensions from Ainley. A quantitative approach using instrument development design was employed. Data analysis was conducted using confirmatory factor analysis (CFA) to evaluate the construct structure. A total of 330 students from grades 4, 5 and 6 were selected through cluster random sampling. The results revealed that the scale consists of four dimensions: learning enthusiasm, learning persistence, learning autonomy, and …


Using A Heuristic Tool To Improve Symptom Self-Management In Adolescents And Young Adults With Cancer: Protocol For A Randomized Controlled Trial., Suzanne Ameringer, Grace Hodges, R K Elswick, Lauri Linder, Catherine Fiona Macpherson, Kristin Stegenga Dec 2025

Using A Heuristic Tool To Improve Symptom Self-Management In Adolescents And Young Adults With Cancer: Protocol For A Randomized Controlled Trial., Suzanne Ameringer, Grace Hodges, R K Elswick, Lauri Linder, Catherine Fiona Macpherson, Kristin Stegenga

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Adolescents and young adults (AYAs) with cancer experience multiple distressing symptoms during treatment, yet few developmentally relevant resources have been developed to help them self-manage their symptoms. Empowering patients to have a more active role in self-management during cancer treatment may lessen their symptom severity and distress.

OBJECTIVE: The aim of this study is to test an intervention designed to improve symptom self-management, the Computerized Symptom Capture Tool (C-SCAT), by helping AYAs understand their unique symptom experience and discuss it with their health care providers.

METHODS: We are conducting a multisite, 2-group randomized controlled trial to evaluate the effects …


Intraventricular Iron Causes Severe Hydrocephalus – A Model Of Severe Neonatal Hydrocephalus, Kwang-Min Kim, Arokoruba Oboba Cheetham-West, Mohamed Rafiuddin Ahmed, Megan Phillips, Andrey V Malkovskiy, Venkata Raveendra Pothineni, Kyle D Brewer, Chirag B Patel, Jayakumar Rajadas, Kelly B Mahaney Dec 2025

Intraventricular Iron Causes Severe Hydrocephalus – A Model Of Severe Neonatal Hydrocephalus, Kwang-Min Kim, Arokoruba Oboba Cheetham-West, Mohamed Rafiuddin Ahmed, Megan Phillips, Andrey V Malkovskiy, Venkata Raveendra Pothineni, Kyle D Brewer, Chirag B Patel, Jayakumar Rajadas, Kelly B Mahaney

Faculty, Staff and Student Publications

Background: Neonatal germinal matrix hemorrhage-intraventricular hemorrhage and subsequent post-hemorrhagic hydrocephalus (PHH) is a leading cause of neurologic morbidity and mortality in preterm infants. Preclinical models of PHH have implicated hemoglobin and iron-mediated cellular injury in the pathogenesis of PHH, but have typically demonstrated a phenotype characterized by mild to moderate ventriculomegaly – the equivalent of which may not even require intervention in the human condition. We sought to establish a preclinical model of severe IVH that recapitulates the severity of the hydrocephalus phenotype requiring neurosurgical intervention and to determine the causal blood degradation product resulting in severe hydrocephalus following preterm …


Cd177+ Neutrophils: New Drivers Of Liver Regeneration, Yankai Wen, Cynthia Ju Dec 2025

Cd177+ Neutrophils: New Drivers Of Liver Regeneration, Yankai Wen, Cynthia Ju

Faculty, Staff and Student Publications

No abstract provided.


Stimulant Medications Affect Arousal And Reward, Not Attention Networks, Benjamin P Kay, Muriah D Wheelock, Ryan V Raut, Roselyne J Chauvin, Athanasia Metoki, Aishwarya Rajesh, Andrew Eck, Jim Pollaro, Anxu Wang, Vahdeta Suljic, Babatunde Adeyemo, Noah J Baden, Kristen M Scheidter, Julia S Monk, Forrest I Whiting, Nadeshka Ramirez-Perez, Samuel R Krimmel, Anita Randolph, Jarod L Roland, Ginger E Nicol, Timothy O Laumann, Scott Marek, Evan M Gordon, Marcus E Raichle, Deanna M Barch, Nico U F Dosenbach, Et Al. Dec 2025

Stimulant Medications Affect Arousal And Reward, Not Attention Networks, Benjamin P Kay, Muriah D Wheelock, Ryan V Raut, Roselyne J Chauvin, Athanasia Metoki, Aishwarya Rajesh, Andrew Eck, Jim Pollaro, Anxu Wang, Vahdeta Suljic, Babatunde Adeyemo, Noah J Baden, Kristen M Scheidter, Julia S Monk, Forrest I Whiting, Nadeshka Ramirez-Perez, Samuel R Krimmel, Anita Randolph, Jarod L Roland, Ginger E Nicol, Timothy O Laumann, Scott Marek, Evan M Gordon, Marcus E Raichle, Deanna M Barch, Nico U F Dosenbach, Et Al.

2020-Current year OA Pubs

Prescription stimulants (e.g., methylphenidate) are thought to improve attention, but evidence from prior fMRI studies is conflicted. We utilized resting-state fMRI data from the Adolescent Brain Cognitive Development Study (n = 11,875; 8-11 years old) and validated the functional connectivity findings in a precision imaging drug trial with highly sampled (n = 5, 165-210 min each) healthy adults (methylphenidate 40 mg). Stimulant-related connectivity differences in sensorimotor regions matched fMRI patterns of daytime arousal, sleeping longer at night, and norepinephrine transporter expression. Taking stimulants reversed the effects of sleep deprivation on connectivity and school grades. Connectivity was also changed in salience …


Effects Of Replacing Antibiotics With Bacillus-Based Probiotics In The Diet Of Lactating Sows On Reproductive Performance, Feed Intake, Serum Immunoglobulin Levels, Milk Production, Oxidative Stress Markers, Fecal Short-Chain Fatty Acids, And Piglet Growth Performance, Chutikan Srisang, Tip-Apa Akkhaphan, Preechaphon Taechamaeteekul, Junpen Suwimonteerabutr, Rafa Boonprakob, Suparlark Nuntawan Na Ayudhya Dr, Lea Hübertz Birch Hansen Dr, Padet Tummaruk Dec 2025

Effects Of Replacing Antibiotics With Bacillus-Based Probiotics In The Diet Of Lactating Sows On Reproductive Performance, Feed Intake, Serum Immunoglobulin Levels, Milk Production, Oxidative Stress Markers, Fecal Short-Chain Fatty Acids, And Piglet Growth Performance, Chutikan Srisang, Tip-Apa Akkhaphan, Preechaphon Taechamaeteekul, Junpen Suwimonteerabutr, Rafa Boonprakob, Suparlark Nuntawan Na Ayudhya Dr, Lea Hübertz Birch Hansen Dr, Padet Tummaruk

The Thai Journal of Veterinary Medicine

This clinical trial investigated the effects of adding a Bacillus-based probiotic to the lactation diet of sows (without in-feed antibiotics) on maternal and piglet outcomes. A total of 109 Landrace × Yorkshire sows (parity 1–7) were assigned to either a control group (n = 61) or a treatment group (n = 48) receiving Bacillus subtilis – 541 and Bacillus amyloliquefaciens – 516. Piglets in the treatment group also received the probiotics via creep feed from day 3 until weaning. Blood samples were collected within 12 h after farrowing to assess serum immunoglobulins (IgG, IgA, and IgM) and malondialdehyde (MDA) …


Rapid Post-Castration Decline In Serum Canine Prostatic Specific Esterase (Cpse) And Prostatic Volume In Dogs With Benign Prostatic Hyperplasia, Panthipa Borikappakul, Junpen Suwimonteerabutr, Suppawiwat Ponglowhapan Dec 2025

Rapid Post-Castration Decline In Serum Canine Prostatic Specific Esterase (Cpse) And Prostatic Volume In Dogs With Benign Prostatic Hyperplasia, Panthipa Borikappakul, Junpen Suwimonteerabutr, Suppawiwat Ponglowhapan

The Thai Journal of Veterinary Medicine

The objectives of this study were to quantify temporal changes in prostatic volume and serum CPSE concentrations in dogs with benign prostatic hyperplasia (BPH) (n = 6) following surgical castration, and to evaluate the potential of CPSE as a biomarker for monitoring prostatic regression. Prostatic volume was determined by transabdominal ultrasonography, and serum CPSE concentrations were measured at baseline (Week 0) and at Weeks 1, 2, and 4 postcastration. The mean (±SE) prostatic volume before castration was 11.4 ± 1.9 cm3 and decreased significantly to 6.3±1.1 cm3 by Week 1 (P < 0.001), representing a reduction to approximately 56% of the baseline value. Smaller progressive declines were observed at subsequent time points up to Week 4 (P > 0.05). In parallel, serum CPSE concentrations dropped …


The Influence Of Early Detection And Intervention Providers' Actions And Communication On Parental Emotions And Early Intervention Engagement After A Child Is Diagnosed With Hearing Loss: A Scoping Review, Charlene M. Watson, D. Ellen Rick, Jillian Ingratta, Patti-Jo Sullivan, Xurong Zhao, Sheila Moodie Dec 2025

The Influence Of Early Detection And Intervention Providers' Actions And Communication On Parental Emotions And Early Intervention Engagement After A Child Is Diagnosed With Hearing Loss: A Scoping Review, Charlene M. Watson, D. Ellen Rick, Jillian Ingratta, Patti-Jo Sullivan, Xurong Zhao, Sheila Moodie

Journal of Early Hearing Detection and Intervention

Despite well-intentioned early hearing detection and intervention (EHDI) programs, parents receiving a newborn hearing loss diagnosis often experience distress, uncertainty, and fear, which can impact their readiness to engage in early intervention. The communication and support provided by clinicians in early hearing detection and intervention play a critical role in helping families navigate emotions, overcome barriers, and actively participate in EHDI programs. The purpose of this scoping review is to advance our knowledge of the following: For parents who have a newborn newly diagnosed with hearing loss, how do the actions/behaviors and communication (or lack thereof) of EHDI providers influence …


Fine And Gross Motor Skills Assessment, From A Caregiver's Perspective, In Children With Hearing Loss Using A Modified Ages And Stages Questionnaire (Asq-3), Steven M. Doettl, Patrick N. Plyler, Erin Plyler, Kelly R. Yeager, Leeann Hutker, Ginger Tallmadge, Aspen Gutknecht, Amy Becker Dec 2025

Fine And Gross Motor Skills Assessment, From A Caregiver's Perspective, In Children With Hearing Loss Using A Modified Ages And Stages Questionnaire (Asq-3), Steven M. Doettl, Patrick N. Plyler, Erin Plyler, Kelly R. Yeager, Leeann Hutker, Ginger Tallmadge, Aspen Gutknecht, Amy Becker

Journal of Early Hearing Detection and Intervention

Purpose: The purpose of this study was to determine if there is a significant difference on ASQ-3 (Ages and Stages Questionnaire version 3) Gross (ASQ G) and Fine (ASQ F) Motor scores between children with sensorineural hearing loss (SNHL) and children with normal hearing.

Methods: Data was gathered from the ASQ-3 as reported by parents/caregivers of 61 children (28 normal hearing children and 33 children with SNHL) ages 6-36 months. Results were averaged across the participants for both groups. Independent sample t-Tests were used to assess for any statistically significant difference in the ASQ scores between groups. Chi-square analysis …


From Policy To Practice In Deaf Education: American Sign Language And Spoken English Outcomes Of Deaf And Hard Of Hearing Children In Kansas, Jena Mcdaniel, Shreyas Teegala, Rebecca Maloney, Angie Walker, Mary S. Dietrich, Matthew L. Hall, Leah C. Geer, Julie Bustos Dec 2025

From Policy To Practice In Deaf Education: American Sign Language And Spoken English Outcomes Of Deaf And Hard Of Hearing Children In Kansas, Jena Mcdaniel, Shreyas Teegala, Rebecca Maloney, Angie Walker, Mary S. Dietrich, Matthew L. Hall, Leah C. Geer, Julie Bustos

Journal of Early Hearing Detection and Intervention

Purpose: In the context of the recent expectation for state Early Hearing Detection and Intervention programs to track language milestones of deaf and hard of hearing (DHH) children, we examine how to leverage statewide assessment programs for improving language outcomes of DHH children. We present the degree to which DHH children in Kansas are meeting their language milestones for American Sign Language (ASL) and English and the influence of two measurement features.

Method: Performance on the ASL/English Language Milestones for 198 children who were DHH (aged 1 to 8) was analyzed for attainment of age-expected language skills and …


Dementia In Downs Syndrome – A Case Report, Clarita Shynal Martis Ms, Elsa Sanatombi Devi Dr, Panambur Venkataraya Bhandary Dr Dec 2025

Dementia In Downs Syndrome – A Case Report, Clarita Shynal Martis Ms, Elsa Sanatombi Devi Dr, Panambur Venkataraya Bhandary Dr

Manipal Journal of Nursing and Health Sciences

Down syndrome, is a chromosome 21-related genetic condition, frequently manifests as intellectual difficulty, growth retardation, and distinctive facial traits. People with Down’s Syndrome usually develop Dementia, a major cause of cognitive impairment, impaired judgment memory loss in their midlife. The present report describes a case study of a female diagnosed with dementia in Down’s Syndrome. The report explores the challenges her parents faced in securing appropriate care when diagnosed with dementia and Down's syndrome. It aims to inform caregivers about the best practices for home care in such cases. It follows the woman's history from birth until her dementia was …


Influence Of Postpartum Depression Among Mothers On Cognitive Development In Children: A Scoping Review, Navyashree Gc, Aabha Jain, Malika Mudit, Manavi Manoj Kumar, Rachna Shetty, Riya Prabhu, Salma Zameer Dec 2025

Influence Of Postpartum Depression Among Mothers On Cognitive Development In Children: A Scoping Review, Navyashree Gc, Aabha Jain, Malika Mudit, Manavi Manoj Kumar, Rachna Shetty, Riya Prabhu, Salma Zameer

Manipal Journal of Nursing and Health Sciences

The interplay of maternal care, communication, and emotional expression of parent-child interactions dramatically influences the cognitive and emotional growth of the child during their formative years. Postpartum depression poses a significant public health concern, impacting mothers' caregiving abilities and infants' sensitive early development. The present scoping review aims to explore the literature that delves into the influence of postpartum depression among mothers on the child’s cognitive development. For this scoping review, a systematic search was conducted for studies in the PubMed and Scopus databases. Studies published in the English language from 1990 to 2023 focusing on mothers with postpartum depression …


Rheumatic Diseases In Pregnancy: Emerging Pharmacologic Management And Safety, Amanda Rawa, Katherine Ghattas Dec 2025

Rheumatic Diseases In Pregnancy: Emerging Pharmacologic Management And Safety, Amanda Rawa, Katherine Ghattas

Transformative Medicine

Rheumatic diseases distinctly affect women of childbearing age, creating complex challenges in balancing maternal disease control with fetal safety during pregnancy and lactation. This review summarizes the pathophysiology and management of common rheumatic diseases, with a focus on the safety and efficacy of conventional and biologic disease-modifying antirheumatic drugs (DMARDs). Particular emphasis is placed on pregnancy-compatible therapies, contraindicated agents, and emerging evidence supporting the use of select biologics such as tumor necrosis factor inhibitors (TNKs). Current guidelines and primary literature have been reviewed to show the importance of preconception counseling and individualized treatment plans to optimize maternal and fetal outcomes.