Medicine and Health Sciences Commons^™

A National Prospective Cohort Study Of Sars/Cov2 Pandemic Outcomes In The U.S.: The Chasing Covid Cohort, Mckaylee Robertson, Sarah Kulkarni, Amanda Berry, Chloe Mirzayi, Andrew Maroko, Rebecca Zimba, Drew Westmoreland, Christina Grov, Angela Parcesepe, Levi Waldron, Denis Nash

Publications and Research

Introduction: The Chasing COVID Cohort (C 3 ) study is a US-based, geographically and socio-demographically diverse sample of adults (18 and older) enrolled into a prospective cohort study during the upswing of the U.S. COVID-19 pandemic.

Methods: We used internet-based strategies to enroll C 3 participants beginning March 28th, 2020. Following baseline questionnaire completion, study participants will be contacted monthly (for 6 months) to complete assessments of engagement in non-pharmaceutical interventions (e.g., use of cloth masks, avoiding large gatherings); COVID-19 symptoms; SARS/COV2 testing and diagnosis; hospitalizations; healthcare access; and uptake of health messaging. Dried blood spot (DBS) specimens will be …

Making Meaning During Coronavirus, Mary Kate Schutt

Population Health Research Brief Series

If you’ve asked yourself, “Why is this happening? What’s the meaning of this?” you’re not alone. This brief discusses why meaning matters and how we might reflect on what we learned about ourselves from the COVID-19 pandemic to make more intentional meaning in our lives.

Changes In Gastroenterology And Endoscopy Practices In Response To The Covid-19 Pandemic: Results From A North American Survey, Zachary L. Smith

Faculty Scholarship

Digestive manifestations appear to be common in patients with coronavirus disease 2019 (COVID19). Gastroenterologists will invariably come into contact with infected patients, and the risk of intraprocedural exposure is well established. Recommendations have been issued to guide personal protective equipment (PPE) use and the triage of procedural urgency, among other operational considerations. In response, institutions providing gastroenterology and endoscopy services have taken urgent action to protect patients and staff, but the uptake and extent of these practice changes in North America is unknown. We conducted a survey of gastroenterology and endoscopy practices to assess the response to the COVID-19 pandemic …

2020-05-04 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Lori D. Sloane, Mari Anixter, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Emma Wolinsky, Fiona Nguyen, Melissa Cossé, Allison Price, Hannah Dowdy-Sue, Ryota Shimada, Susie Pham, Ariel Hurwitz, Alexandra Yingling, Elly Munde, Perez Olewe, Cristian Bologa, Gregory Mertz, Kristine Tollestrup, Orrin Myers, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

NM convalescent plasma call. NM case counts. Gallup lockdown continues. Tribal federal relief delay. Childcare demand drops. Polling open for primaries. Non-US world funds R&D. South Korea eases more. Soft quarantine inefficiency. Chinese interventions. Transmission window. December French case. CDC on law enforcement, essential errands. NEJM on telemedicine. Practice guidelines for: ECMO, pneumonia, nuclear medicine SOP. FDA antibody test restrictions. Africa testing differences. PCR assay sensitivity. Wuhan antibody tracking. Hydroxychloroquine toxicity. Remdesivir mechanism. Tocilzumab study inconclusive. SARs-CoV-2 structure. 28 new trials. Immunology and exercise. Synthetic SARS-CoV-2. IgM and IgG responses. Bacterial and fungal coinfection. Youth mental health challenges.

Knowledge Graph-Enabled Cancer Data Analytics, S M Shamimul Hasan, Donna Rivera, Xiao-Cheng Wu, Eric B. Durbin, J Blair Christian, Georgia Tourassi

School of Public Health Faculty Publications

Cancer registries collect unstructured and structured cancer data for surveillance purposes which provide important insights regarding cancer characteristics, treatments, and outcomes. Cancer registry data typically (1) categorize each reportable cancer case or tumor at the time of diagnosis, (2) contain demographic information about the patient such as age, gender, and location at time of diagnosis, (3) include planned and completed primary treatment information, and (4) may contain survival outcomes. As structured data is being extracted from various unstructured sources, such as pathology reports, radiology reports, medical records, and stored for reporting and other needs, the associated information representing a reportable …

Week Of May 4, 2020, New York Medical College

InTouch

• NYMC Collaborates with Regeneron for COVID-19 Clinical Drug Trials
• Join NYMC for the Third COVID-19 Symposium, The Next Phase of Clinical and Public Health Management
• Health Sciences Library Continues to Provide Service
• Join NYMC for a Global Day of Giving and Unity, #GivingTuesdayNow

Why Do Graduates Choose To Work In A Less Attractive Specialty? A Cross-Sectional Study On The Role Of Personal Values And Expectations, Van Anh Nguyen, Karen D. Könings, E Pamela Wright Phd, Ms, Med, Rn, Cen, Giang Bao Kim, Hoat Ngoc Luu, Albert J. Scherpbier, Jeroen J. Van Merriënboer

Publications

BACKGROUND: Primary health care (PHC), of which preventive medicine (PM) is a subspecialty, will have to cope with a deficiency of staff in the future, which makes the retention of graduates urgent. This study was conducted in Vietnam, where PM is an undergraduate degree in parallel to medical training. It aims to identify facilitating and hindering factors that impact recruitment and retention of PM graduates in the specialty. METHODS: A cross-sectional study enrolled 167 graduates who qualified as PM doctors from a Vietnamese medical school, between 2012 and 2018. Data were collected via an online questionnaire that asked participants about …

Developing The Pedis Pediatric Obstructive Sleep Apnea Screening Tool, Steven Sumpter

Doctor of Nursing Practice Projects

Obstructive sleep apnea (OSA) is the most common type of apnea in the pediatric population. Its prevalence is 0.7%-3.0% (Garcia et al., 2016). The dangers of OSA are multiplied in conjunction with anesthesia because anesthesia resembles a state of sleeping, relaxing the airway, and requiring more intense airway monitoring. Childhood OSA includes increased risk for developing neurocognitive impairment, behavioral problems, failure to thrive, hypertension, cardiac dysfunction, systemic inflammation, and increased healthcare costs (Kothare et al., 2015). A perioperative pediatric OSA screening tool is necessary to reduce airway risks. The PEDIS screening tool is a brief, efficient, and evidence-based tool capable …

Hereditary Cancer Syndrome Recognition And Testing: Beyond Brca, Deborah O. Himes, Hanford B. Shuman

Faculty Publications

Hereditary cancer syndromes, resulting from mutations of tumor suppressor genes, can significantly increase the risk for breast cancer. Although hereditary breast and ovarian cancer syndrome caused by BRCA1/2mutations is well-known, less well-known hereditary cancer syndromes also exist. This article focuses on 3 other syndromes, including Li-Fraumeni, Cowden, and Peutz-Jeghers. This article will help prepare nurse practitioners to recognize key clinical features of these syndromes and understand testing criteria. Additionally, this article discusses barriers to diagnosing hereditary cancer syndromes and the role of primary care nurse practitioners in ordering genetic tests and making genetic referrals for optimal patient care.

Using A Novel Cell- Penetrating Peptide Technology To Induce Pluripotency, Laura-Maria Oja

Master of Science in Chemical Sciences Theses

Somatic stem cells have been used as a regenerative medicine tool to treat diseases like leukemia for decades, but they are limited in their ability to self-renew and differentiate. A better alternative, induced pluripotent stem cells (iPSCs), has the ability to generate cells from all three germ layers and avoid tissue rejection as well as bypass the ethical concerns related to embryonic stem cells. In 2006, Takahashi and Yamanaka discovered that only four genes were required to induce pluripotency: Oct4, Sox2, Klf4, and c-Myc (OSKM). Since then, pluripotency has been induced with OSKM most effectively by transfection or transduction. However, …

How Misinformation And Mistrust Compound The Threat Of Epidemics, William Boyd

Honors Theses

This thesis was conducted to study the effects of misinformation and medical mistrust on the public health field. I use the events of the Chapare Virus outbreak in Bolivia in the summer of 2019 and the public dialogue during that time period to discuss these themes. I used data from market survey's in La Paz, newspaper articles from Página Siete, and Tweets from the time period of the outbreak. My findings suggest that misinformation and medical mistrust affected public health measures, which has major implications for the way the public health field should address future public health events.

Nk Cell-Derived Gm-Csf Potentiates Inflammatory Arthritis And Is Negatively Regulated By Cis, Cynthia Louis, Fernando Souza-Fonseca-Guimaraes, Yuyan Yang, Damian D'Silva, Tobias Kratina, Laura Dagley, Soroor Hediyeh-Zadeh, Jai Rautela, Seth Lucian Masters, Melissa J Davis, Jeffrey J Babon, Bogoljub Ciric, Eric Vivier, Warren S Alexander, Nicholas D Huntington, Ian P Wicks

Department of Neurology Faculty Papers

Despite increasing recognition of the importance of GM-CSF in autoimmune disease, it remains unclear how GM-CSF is regulated at sites of tissue inflammation. Using GM-CSF fate reporter mice, we show that synovial NK cells produce GM-CSF in autoantibody-mediated inflammatory arthritis. Synovial NK cells promote a neutrophilic inflammatory cell infiltrate, and persistent arthritis, via GM-CSF production, as deletion of NK cells, or specific ablation of GM-CSF production in NK cells, abrogated disease. Synovial NK cell production of GM-CSF is IL-18–dependent. Furthermore, we show that cytokine-inducible SH2-containing protein (CIS) is crucial in limiting GM-CSF signaling not only during inflammatory arthritis but also …

The Gossypium Longicalyx Genome As A Resource For Cotton Breeding And Evolution, Corrinne E Grover, Mengqiao Pan, Daojun Yuan, Mark A Arick, Guanjing Hu, Logan Brase, David M Stelly, Zefu Lu, Robert J Schmitz, Daniel G Peterson, Jonathan F Wendel, Joshua A Udall

2020-Current year OA Pubs

Cotton is an important crop that has made significant gains in production over the last century. Emerging pests such as the reniform nematode have threatened cotton production. The rare African diploid species

Triad Of Anxiety: A Qualitative Analysis For Anxiety In Nursing Student Collegiate-Athletes, Morgan Vanderschaaf, Sharon Webb, Abby Garlock

Journal of Counseling and Psychology

Anxiety and resulting implications are prevalent for collegiate athletes who are also in nursing studies. These authors conducted a qualitative research study to analyze perceptions of nursing student-athlete’s anxiety and feelings of perfectionism. Three main research questions were investigated: What impact does anxiety have on a nursing student-athletes? How does perfectionism affect a nursing-student athlete's anxiety? How can coaches and professors aid in the reduction of the nursing student-athlete's anxiety? Interviews were recorded, transcribed, and then coded. Resulting phenomena led to the concept of the Triad of Anxiety. Results indicated that nursing student-athletes experienced perceived threats, negative internal experiences, and …

Life During A Pandemic, Srinivasan Ragothaman

Creative Work

This is a short poem (6 stanzas) about the current pandemic and the trials and tribulations people are going through. This describes the heroic efforts by the doctors, nurses, and other frontline warriors in tackling the virus related illnesses and pays a rich tribute to all heroes from every walk of life who are in the front fighting this disease. It hopes for a plan, a vaccine, and a cure soon. This poem also describes the switchover to remote instruction at a reginal University, student and faculty adjustments to the pandemic and pokes gentle fun at the opportunity to watch …

Medical School Watercooler Newsletter - May 3, 2020, Lindsey Lyle

Watercooler Newsletter

This is the May 3, 2020 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Petty champions the prevention of e-cigarette use in children

Surgery and pharmacology faculty member featured in ACCESS Magazine

New addiction medicine fellowship first of its kind in Alabama

Does The Us Have The Worst Maternal Mortality Rate?, Elizabeth Adale Ellis

2020 Symposium Posters

The maternal mortality rate in America is currently very high and is increasing every year. Currently the maternal mortality rate in America is 16.9 deaths for every 100,000 births. America is ranked 138 out of 184 in the worlds maternal mortality rate scale. This is seemingly very high seeing as we are a developed first world country and we have the information to help lower this rate. In this study it will review maternal mortalities rates worldwide and compare maternal practices in other countries to Americas maternal practices. There are many documents and scholarly works on maternal mortality around the …

2020-05-03_Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

The webpage was obtained from Michigan's Coronavirus Cumulative Data page, under the link Data About Places. Data is self-reported by hospitals daily to the EM Resource System per MDHHS Director Robert Gordon's Emergency Order.

Contains the tables Statewide Available Bed Tracking for COVID-19, COVID-19 Metrics, Statewide Available PPE Tracking for COVID-19 (Statewide Available PPE and Bed Tracking), as well as the tables PPE Days On Hand and Patient Census.

2020-05-03_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …

2020-05-03_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was captured from the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_99207---,00.html.

The website contained the table Count of Confirmed COVID-19 Cases by Date of Onset , sorted by Michigan Preparedness Region. It also contained 18 charts, including the count of confirmed Covid-19 cases by date of onset in the state overall as well as in each preparedness region,and the normalized rate of Covid-19 cases per 1,000,000 residents in both the state and in each preparedness region.

2020-05-03_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173-526911--,00.html.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data is updated on an ongoing basis.

MDHHS has established a regional hub strategy to assist in reducing the spread of COVID-19 within nursing facilities. COVID-19 Regional Hubs have established units dedicated to treating COVID-19-affected individuals and have established appropriate staffing levels and protocols to support this level of care.
These case counts reflect current cases of COVID-19 among facility residents reported …

2020-05-03_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https:/www.michigan.gov/coronavirus/0,9753,7-406-98163-520743--,00.html. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., with COVID-19 results included as of 10 a.m.

Note on cumulative counts: This report is provisional and subject to change. As public health investigations of individual cases continue, there will be corrections to the status and details of referred cases that result in changes to this report.
Note on the deaths: Deaths must be reported by health care providers, medical examiners/coroners, and recorded by local health departments …

Pandemic Simulator (Issue 3, 3 May 2020), Nazar Zaki, Tetiana Habuza, Stefanache Cornel

Covid19 Newsletters

No abstract provided.

2020-05-02/03 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Lynnmarie Jarratt, Melissa Cossé, Samantha Paltrow-Krulwich, Stephen Esguerra, Hannah Dowdy-Sue, Ariel Hurwitz, Alexandra Yingling, Clinton Onyango, Tudor I. Oprea, Gregory Mertz, Orrin Myers, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

More NM cases. Free Shiprock testing. Prison release demands. 8 state parks reopen. Higher US deaths. NY PPE case dismissed. Orthopedic Tx down. European deaths down. UK mortality factors. People leaving large cities. Ending lockdown strategies. Public mask impact. Taiwan tracing. Homeless shelter prevalence. Homeless shelter outbreak. 50-state R0. COVID-19 decades later. US county tracking site. Hospital management model. COVID-19 behavioral transformation. Practice guidelines for: cardiology, IBD surgery, and rheumatic physical inactivity. Roche antibody test approved. Abbott antibody test EU-certified. Home anosmia assessment. CVD and ACE/ARBs. Tocilizumab early evidence. Tocilizumab systematic review. WHO vaccines trial. HCQ slower viral …

Oral Care And Ventilator Associated Pneumonia Prevention, Rachel Baber

MSN Capstone Projects

With rising healthcare costs and increasing demands placed on healthcare workers, it is no wonder that decreasing hospital length of stay for patients is high priority for hospitals today. Hospital acquired infections are one of the culprits keeping so many patients hospitalized. Specifically, in intensive care units (ICU) and intermediate care (IMC) units that care for mechanically ventilated patients, ventilator associated pneumonia secondary to intubation is a complication and cost that is being sought to be avoided. Hospitals have been pro-active to prevent ventilator associated pneumonia from occurring by placing oral care bundles or protocols in place to care for …

Health Care Access For Children In Latinx Immigrant Families In The Greater Philadelphia Area, Sophia King

Politics Honors Papers

This work examines the gap that exists in access to health care in the Greater Philadelphia Region for children of Latinx immigrant families in comparison to other children in the nation. It provides a critical analysis of the gap in access to coverage, noting that this exists despite wide support for a human right to health. This study draws on existing scholarly research as well as interviews with staff at two health clinics and one community outreach center that are located in Greater Philadelphia. It demonstrates that Latinx immigrant families are less likely to have health insurance and get primary …

Apc-Β-Catenin-Tcf Signaling Silences The Intestinal Guanylin-Gucy2c Tumor Suppressor Axis., Erik S Blomain, Jeffrey A Rappaport, Amanda M Pattison, Babar Bashir, Ellen Caparosa, Jonathan Stem, Adam E Snook, Scott A Waldman

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Sporadic colorectal cancer initiates with mutations in APC or its degradation target β-catenin, producing TCF-dependent nuclear transcription driving tumorigenesis. The intestinal epithelial receptor, GUCY2C, with its canonical paracrine hormone guanylin, regulates homeostatic signaling along the crypt-surface axis opposing tumorigenesis. Here, we reveal that expression of the guanylin hormone, but not the GUCY2C receptor, is lost at the earliest stages of transformation in APC-dependent tumors in humans and mice. Hormone loss, which silences GUCY2C signaling, reflects transcriptional repression mediated by mutant APC-β-catenin-TCF programs in the nucleus. These studies support a pathophysiological model of intestinal tumorigenesis in which mutant APC-β-catenin-TCF transcriptional regulation …

Replacing A Single Tooth: Single Implant Vs. Three Unit Bridge, Ibeth Erazo, Aneeza Hussain

Publications and Research

There are more than two options for restoring a single tooth but our research includes a three-unit bridge and a single-tooth implant as the main options. In this paper, we discuss the advantages and disadvantages of these methods and the factors that must be considered when choosing between them for the replacement of a single tooth. Although in some cases a three-unit bridge is the most appropriate choice, implants have the advantage of allowing preservation of the integrity of sound teeth adjacent to the edentulous area. Many factors must be considered when choosing between a three-unit bridge and an implant …

2020-05-02_Michiganoverview_Covidcounts, Michigan Department Of Health & Human Services

Michigan COVID-19 Confirmed Cases by Date of Onset Data

Data was captured from the Cumulative Data link of Michigan's Coronavirus webpage, under the url https://www.michigan.gov/coronavirus/0,9753,7-406-98163_98173_99207---,00.html.

The website contained the table Count of Confirmed COVID-19 Cases by Date of Onset , sorted by Michigan Preparedness Region. It also contained 18 charts, including the count of confirmed Covid-19 cases by date of onset in the state overall as well as in each preparedness region,and the normalized rate of Covid-19 cases per 1,000,000 residents in both the state and in each preparedness region.

2020-05-02_Michigandaily_Covidmap, Michigan Department Of Health & Human Services

Daily Michigan COVID-19 Update

The "WHERE WE STAND WITH COVID-19" map was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily at 3p.m., Monday - Saturday.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled.

The image contained a map, indicating total cases by county, and also provides statistics on Total Confirmed Cases, Total COVID-19 Deaths, Daily Confirmed Cases, and Daily COVID-19 Deaths. There …