Medicine and Health Sciences Commons^™

Extreme Elevations Of Alkaline Phosphatase In Pregnancy: A Case Report, Zachary Stanley, Katherine Vignes, Miriam Marcum

Obstetrics and Gynecology Faculty Publications

Background: The normal serum concentration of alkaline phosphatase (ALP) in adults over the age of 18 ranges from 37 to 116 U/L, while in pregnant women levels of up to twice that upper limit can still be normal. There have been very few reports of extreme elevations in ALP, and here we present the case of a 29-year-old pregnant woman with an incidentally found 30-fold increase.

Case: The patient, G6P2-1-2-4, received routine prenatal care, though presented to obstetric triage at 36 weeks and 1 day of gestation for diagnosis and management of viral rhinosinusitis and was found to have an …

Conocimientos, Actitudes Y Prácticas Relacionadas A La Pandemia Del Covid-19 En Comunidades Indígenas De Yucatán Y Chiapas, Isabel Vieitez Martínez, Silvana Larrea, Fabiola Romero, Ludivine Cicolella

Poverty, Gender, and Youth

La Organización Mundial de la Salud ha recientemente indicado su preocupación sobre el mayor impacto que está teniendo y tendrá la pandemia por Covid-19 en la población indígena de América Latina. Aún cuando los resultados del presente estudio no sean representativos de toda la población indígena que vive en los municipios de Chiapas y Yucatán donde se realizó la encuesta, consideramos que los datos pueden identificar dimensiones que necesitan estudiarse a mayor detalle. También pueden guiar algunas de las acciones de las organizaciones locales que trabajan en estas comunidades, señalando áreas de oportunidad con respecto a conocimientos, actitudes y prácticas, …

Endovascular Treatment Of Cervical Myelopathy From Brachiocephalic Venous Stenosis., Craig Schreiber, Alex Anavim, Mark Kotapka, Paul Brady

Neurosurgery Resident Research

Central venous stenosis is a rare cause of neurologic pathology. Here we present a case of brachiocephalic vein stenosis causing cervical myelopathy through venous engorgement. Our patient was a 51-y/o male who presented with ambulatory dysfunction so he was evaluated for cervical myelopathy. Imaging revealed cord compression from venous engorgement and brachiocephalic vein stenosis. He was treated with angioplasty and vessel stenting which significantly improved flow on postintervention imaging. In conclusion, preoperative vascular imaging should be considered in myelopathic patients as it can detect this rare but dangerous etiology.

No Longer Expert: A Meta-Synthesis Describing The Transition From Clinician To Academic, Jane S. Grassley, Pamela K. Strohfus, Andrea C. Lambe

Nursing Faculty Publications and Presentations

Background: Recruitment of nurse clinicians into academic nursing has been important in addressing the faculty shortage. A description of their experiences as novice faculty could provide insights into easing their transition and improving faculty retention. Method: A systematic review of existing qualitative evidence was conducted to describe how nurses experience the transition from clinical practice to nursing academic. Criteria established by the Joanna Briggs Institute guided the review. Results: The meta-synthesis of the 12 selected qualitative studies yielded 11 themes and four meta-themes, which included: Unprepared, No Longer an Expert, In Search of Mentoring, and Beginning to Thrive. Conclusion: The …

Dosimetric Comparison Of Hypofractionated Prostate Radiation With Simultaneous Integrated Boost And Conventional Fractionation With Sequential Boost, Kristina Sammon

Masters Projects

Introduction: Hypofractionated treatment delivery regimens are associated with better overall long-term disease control for prostate cancer. For patients with high-risk disease, there may be an indication for treatment of the surrounding pelvic lymph nodes for better over-all disease control. In order to achieve a hypofractionated regimen with treatment to the surrounding pelvic lymph nodes a simultaneous integrated boost technique is employed. There are concerns regarding achievability of target dose coverage and limitation of dose to the surrounding organs at risk with this fractionation.

Methods: This study is a retrospective dosimetric analysis of 7 randomly selected patients with high-risk prostate cancer. …

Camps: Efficient And Privacy-Preserving Medical Primary Diagnosis Over Outsourced Cloud, Jianfeng Hua, Guozhen Shi, Hui Zhu, Fengwei Wang, Ximeng Liu, Hao Li

Research Collection School Of Computing and Information Systems

With the flourishing of ubiquitous healthcare and cloud computing technologies, medical primary diagnosis system, which forms a critical capability to link big data analysis technologies with medical knowledge, has shown great potential in improving the quality of healthcare services. However, it still faces many severe challenges on both users' medical privacy and intellectual property of healthcare service providers, which deters the wide adoption of medical primary diagnosis system. In this paper, we propose an efficient and privacy-preserving medical primary diagnosis framework (CAMPS). Within CAMPS framework, the precise diagnosis models are outsourced to the cloud server in an encrypted manner, and …

World-Wide Fingers Network: A Global Approach To Risk Reduction And Prevention Of Dementia, Miia Kivipelto, Francesca Mangialasche, Heather M. Snyder, Ricardo Allegri, Sandrine Andrieu, Hidenori Arai, Laura Baker, Sylvie Belleville, Henry Brodaty, Sonia M. Brucki, Ismael Calandri, Paulo Caramelli, Christopher Chen, Howard Chertkow, Effie Chew, Seong H. Choi, Neerja Chowdhary, Lucía Crivelli, Rafael De La Torre, Yifeng Du, Tarun Dua, Mark Espeland, Howard H. Feldman, Maris Hartmanis, Tobias Hartmann, Megan Heffernan, Christiani J. Henry, Chang H. Hong, Krister Hakansson, Takeshi Iwatsubo, Jee H. Jeong, Gustavo Jimenez-Maggiora, Edward H. Khoo, Lenore J. Launer, Jenni Lehtisalo, Francisco Lopera, Pablo Martinez-Lage, Ralph Martins, Lefkos Middleton, Jose L. Molinuevo, Manuel Montero-Odasso, So Y. Moon, Kristal Morales-Perez, Ricardo Nitrini, Haakon B. Nygaard, Yoo K. Park, Markku Peltonen, Chengxuan Qiu, Yakeel T. Quiroz, Rema Raman, Naren Rao, Vijayalakshmi Ravindranath, Anna Rosenberg, Takashi Sakurai, Rosa M. Salinas, Philip Scheltens, Gustavo Sevlever, Hilkka Soininen, Ana L. Sosa, Claudia K. Suemoto, Mikel Tainta-Cuezva, Lina Velilla, Yongxiang Wang, Rachel Whitmer, Xin Xu, Lisa J. Bain, Alina Solomon, Tiia Ngandu, Maria C. Carrillo

Research outputs 2014 to 2021

© 2020 The Authors. Alzheimer's & Dementia published by Wiley Periodicals, Inc. on behalf of Alzheimer's Association Reducing the risk of dementia can halt the worldwide increase of affected people. The multifactorial and heterogeneous nature of late-onset dementia, including Alzheimer's disease (AD), indicates a potential impact of multidomain lifestyle interventions on risk reduction. The positive results of the landmark multidomain Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) support such an approach. The World-Wide FINGERS (WW-FINGERS), launched in 2017 and including over 25 countries, is the first global network of multidomain lifestyle intervention trials for dementia risk …

Black Midwifery In The United States: Past, Present, And Future, Alicia Suarez

Sociology & Anthropology Faculty publications

While sociologists have long explored health and illness, much of it has been androcentric and White-centered. Scholars began to focus more on women’s health including pregnancy and birth in the 1970s yet have historically largely ignored Black women’s birth experiences. Midwifery in the United States was once the standard practice for prenatal care and birth. However, the vast majority of births have been medicalized and now occur in hospital settings. In this review, I will highlight the role of race in the historical shifts in the provision of care to Black pregnant and birthing women, the marginalization of Black midwives …

Evaluating The Utilization Of A Combination Therapy To Improve Self-Efficacy And Glycemic Control In Patients With Type Two Diabetes Mellitus And Low Health Literacy, Crystal Manus Masling

Doctoral Dissertations and Projects

Type 2 diabetes mellitus is a significant health issue, as it requires patients to perform daily self-management activities. One in every three Americans with Type 2 diabetes has limited or low health literacy skills. Limited or low health literacy skills can impact a patient’s overall health outcome; therefore, a critical element for disease management and patient adherence is health literacy. The purpose of this three-month scholarly project was to determine if the utilization of an educational intervention specific to one’s level of health literacy, combined with a short message service reinforcement tool, could improve glycemic control and self-efficacy in Type …

Improving Newborn Outcomes Through Implementation Of Delayed Bathing: An Integrative Review, Tennille Ideen O'Connor

Doctoral Dissertations and Projects

Evidence-based practice is foundational to ensuring patient safety and quality of care. Implementing evidence-based practice is the responsibility of all care providers. The completion of an in-depth integrative review provides a project leader the opportunity to explore the benefits of delayed bathing of the newborn and impact of the practice on newborn outcomes. The goal of this integrative review is to identify the benefits of delayed bathing and ways to implement this practice in the clinical setting. This integrative review seeks to present care providers with the most recent research and guidelines as it relates to the practice of delayed …

Peer Intervention With Suicidal Disclosures On Social Media: Does The Bystander Effect Play A Role?, Carissa M. Orlando

Theses and Dissertations

Suicide is an increasing public health concern in adolescents and young adults, and many individuals discuss mental health concerns with friends in lieu of professional avenues. Thus, peers can serve as valuable gatekeepers for friends experiencing suicidality. The prevalence of social networking websites means that individuals are likely to encounter suicidal disclosures on the internet, but little research has investigated if young adults possess the skills and motivation to intervene in these contexts. Additionally, there have been virtually no investigations into how the presence of other online users impacts intervention behavior—in short, if there exists a bystander effect. This study …

Initial And Repeated Point Prevalence Surveys To Inform Sars-Cov-2 Infection Prevention In 26 Skilled Nursing Facilities - Detroit, Michigan, March-May 2020, Guillermo V. Sanchez, Caitlin Bierdon, Lauren R. Fink, Kelly M. Hatfield, Jordan Micah F. Polistico, Monica P. Meyers, Rebecca S. Noe, Casey E. Copen, Amanda K. Lyons, Gonzalo Gonzalez, Keith Kiama, Mark Lebednick, Bonnie K. Caander, Amen Agbonze, Aimee R. Surma, Avnish Sandhu, Valerie H. Mika, Tyler Prentiss, John Zervos, Donia A. Dalal, Amber M. Vasquez, Sujan C. Reddy, John Jernigan, Paul E. Kilgore, Marcus J. Zervos, Teena Chopra, Carla P. Bezold, Najibah K. Rehman

Department of Pharmacy Practice

No abstract provided.

Evaluating Public Posting, Goal Setting, And Rewards To Increase Physical Activity In Children, Bryon G. Miller

USF Tampa Graduate Theses and Dissertations

In Experiments 1 and 2 we evaluated a pedometer-based intervention consisting of public posting between two teams of students, with additional self-monitoring, goal setting, and reinforcement components, to increase physical activity during school recess. In the absence of self-monitoring, performance feedback alone did not increase physical activity levels above those observed during baseline. Additionally, higher levels of physical activity were observed when goal-setting was introduced, with the highest levels of activity observed when raffle tickets could be earned for exceeding a specified step-total goal. In Experiment 3 we removed the team component and evaluated similar intervention components across an entire …

Four Health Science Librarians’ Experiences: How They Responded To The Covid-19 Pandemic Crisis, Misa Mi, Yingting Zhang, Lin Wu, Wendy Wu

Library Scholarly Publications

In this article, four health sciences librarians from four academic libraries across the country will share their personal or library experiences in reaching out to faculty and students to meet their needs through their initiatives and continuous efforts using various technologies and tools. Three of the four academic libraries are located in two COVID-19 hard-hit states, Michigan and New Jersey. The article will describe their practice of health sciences librarianship during the unprecedented time and provide examples demonstrating how each of them strives to stay relevant, proactive, and become integral to their institutional efforts in support of students and employees …

Patient Personalized Fall Prevention, Olivia Mennig Bsn, Rn, Anne Kearns Bsn, Rn

Vizient/ AACN Nurse Residency Program™ EBP Projects

No abstract provided.

Sound Discrimination And Explicit Mapping Of Sounds To Meanings In Preschoolers With And Without Developmental Language Disorder, Carolyn Quam, Holly Cardinal, Celeste Gallegos, Todd Bodner

Speech and Hearing Sciences Faculty Publications and Presentations

Purpose: To investigate links between sound discrimination and explicit sound-meaning mapping by preschoolers with and without developmental language disorder (DLD).

Method: We tested 26 children with DLD and 26 age- and gender-matched peers with typical language development (TLD). Inclusion was determined via results of standardised assessments of language and cognitive skills and a hearing screening. Children completed two computerised tasks designed to assess pitch and duration discrimination and explicit mapping of pitch- and duration-contrasting sounds to objects.

Result: Children with TLD more successfully mapped pitch categories to meanings than children with DLD. Children with TLD also showed significantly better overall …

Challenges Of Doing Alzheimer’S Research In Costa Rica And Some Possible Solutions, Felipe Mejias

International Programs

Alzheimer's disease is a public health priority which has been researched for many years in the hope of finding a cure soon. Costa Rica has made significant progress in many areas of research; however, the research carried out in the country on Alzheimer's disease is very scarce. The present poster presents the challenges of developing scientific Alzheimer’s research in Costa Rica by reviewing current scientific research on Alzheimer's in Costa Rica and by conducting interviews with Costa Rican professionals who have conducted Alzheimer's research. The lack of investigative training of doctors, the difficulties in accessing patient data, and the lack …

Redefining The Meanings Of Daily-Occupations And Life Quality Amongst Mothers Living With Their Autistic Children, Eko Sumaryanto, Gandes Mutiara Aziz

International Programs

Raising children with autism is very challenging for mothers due to changes on how occupational performance and occupational roles are performed. This circumstance demands these mothers to redefine the meaning of doing occupations and how they perceive their well-being in general. This study empirically investigates how mothers redefine the meaning of daily activities and self-report their well-being. The study employs in-depth interviews and formulates specific themes of findings. The study uses the phenomenology approach to investigate the dynamics of meanings experienced by the respondents and how they construct the new version of well-being from raising the autistic children.

A Health Care Comparison Of Areas In Ghana And In The United States, Lindsey Matsumoto

Honors Projects

The health care system is an important factor for the well-being of the human population all around the world, and yet, health care can differ greatly depending on a variety of factors including location and culture. When referring to health care, it is appropriate to include skilled physicians, hospitals, care clinics, and medical equipment. This article conducts a literature review that compares the health care systems of two countries, the Republic of Ghana and the United States of America. This information is relevant for not only expanding one’s knowledge, but also for travel purposes, as both countries have highly populated …

Systematic Review With Meta-Analysis: Prevalence Of Prior And Concurrent Barrett’S Oesophagus In Oesophageal Adenocarcinoma Patients, Mimi C Tan, Nabil Mansour, Donna L White, Amy Sisson, Hashem B El-Serag, Aaron P Thrift

Library Staff Publications

BACKGROUND: The proportions of patients with oesophageal adenocarcinoma (OAC) diagnosed by Barrett's oesophagus surveillance or with pre-existing Barrett's oesophagus are unclear.

AIM: To estimate the prevalence of prior and concurrent Barrett's oesophagus diagnosis among patients with OAC or oesophagogastric junction adenocarcinomas (OGJAC).

METHODS: We searched PubMed and Embase to identify studies published 1966-1/8/2020 that examined the prevalence of prior (≥6 months) or concurrent Barrett's diagnosis (at cancer diagnosis) among OAC and OGJAC patients. Random effects models estimated overall and stratified pooled prevalence rates.

RESULTS: A total of 69 studies, including 33 002 OAC patients (53 studies) and 2712 patients with …

Polycystic Ovarian Syndrome: Causes, Complications, And Treatments, Toni Tornberg

Biomedical Sciences Undergraduate Research

Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder prevalent in 6-10% of reproductive age women. The purpose of this review paper is to describe both genetic and environmental causes and symptoms of PCOS. Additionally, to summarize the complications women face with a PCOS diagnosis and present treatment and management options. The information forming this paper was compiled from various online heath journals. The results show that both clinical and biochemical examinations are used for the diagnosis of PCOS while the exact cause is unknown. Genetics and environmental factors, specifically the intrauterine environment, are discussed as causes. Management and treatment options …

Microbial Experience Influences Tumor- Infiltrating T Lymphocytes, Hanna Groeber

Masters Theses

Immune cells, including T cells, have been used for anti-cancer therapy with varying degrees of success. One potential reason for immunotherapy failures in clinical trials may be that typical specific pathogen free (SPF) mice do not accurately replicate human microbial experience, which has important influence on shaping the adaptive immune response. Recently, several previous studies have shown that the immune system of SPF mice more closely resembles newborn human immunity, whereas immune systems from mice exposed to diverse pathogens more closely reflect adult human immunity.

To study the impact of microbial experience on the immune response, we have adopted a …

Barriers And Facilitators To Voting For People With Disabilities In Michigan Rural Communities, Christian Aguilar-Quiroz, Kaylyn Brzys, Chris Paclibar, Kyle Witte

Community Based

Objective: In this study, we sought to investigate and obtain data on the perceived barriers and facilitators that rural Michigan residents with disabilities face throughout the voting process.

Method: We conducted two separate focus groups in two different rural areas of Michigan asking a series of semi-structured questions about the participants’ voting experiences. We obtained recorded interviews, qualitative data, of their answers to these prepared questions.

Results: Physical accessibility was limited by poor lighting for people with low vision problems and a lack of accommodations for those who are not able to stand for a prolonged time while waiting in …

The Perceived Effects Of Occupational Therapy Interventions For Those Who Recently Transitioned From Homelessness To Permanent Housing, Sydney Krol, Madison Muir, Katie Johnson, Kristin Hazlett, Kaelyn Hughs

Community Based

OBJECTIVE. The study's objective was to examine the perceived effects of occupational therapy services for families who have recently transitioned to permanent housing from a period of homelessness.

METHOD. The study used a qualitative research design. One family received occupational therapy interventions administered by occupational therapy student researchers. Exit interview was audio recorded and transcribed.Themes and codes were derived from the transcription.

RESULTS. Three themes and seven codes were identified, which encompassed the participants perception of the intervention. The themes were lifestyle transformation, mindset development, and client centered care. The codes were organization and planning, roles and routines, goal progression, …

Occupation-Based Learning Modules In Preparation For Parole: A Program Evaluation, Alisha Cheyne, Gabrielle Martino, Elizabeth Vander Wall, Natalie Wallace

Community Based

A qualitative research study was conducted that examined occupational therapy students’ fieldwork rotation at Muskegon Correctional Facility, where they implemented a 15-week pre-parole program. One focus group with three participants was conducted. Transcription, coding, and theming followed, providing five themes; restriction, OT perceptions, learning styles, future needs, and relationships. Results showed areas of needs within this population, ways occupational therapy can address this need, and general improvements that can be made to pre-release programs.

Exploratory Study Of Children With Sensory Processing Disorder (Spd) Without An Autism Spectrum Disorder (Asd) Diagnosis, Breanna Williams, Lauren Brown, Kendall Grzywa, Emma Green

Pediatrics

The purpose of this study was to explore the prevalence of children with sensory processing disorder (SPD) without an autism spectrum disorder (ASD) diagnosis. Examples of these diagnoses include attention deficit hyperactivity disorder (ADHD), cerebral palsy (CP), posttraumatic stress disorder (PTSD), Oppositional Defiant Disorder (ODD), and Reactive Attachment Disorder (RAD). This was an exploratory descriptive study that gathered quantitative data through the Sensory Processing Measure (SPM) Home Form. The SPM Home Form was provided by occupational therapy (OT) students and completed by the child’s caregiver. The scores fell into three interpretive ranges: Typical, Some Problems, and Definite Dysfunction. Researchers hypothesized …

Caregiver Perspective On Sensory Diet And Therapeutic Listening For Children With Autism Spectrum Disorder And/Or Sensory Processing Disorder, Mikayla M. Brett, Lynette Zulquairnain, Katlyn Ribant

Pediatrics

Due to the high prevalence of Autism Spectrum Disorder (ASD) and Sensory Processing Disorder (SPD), there is a high demand for more research on effective interventions in order to improve quality of life and engagement in meaningful occupations for individuals with ASD and/or SPD. Sensory Diet (SD) and Therapeutic Listening © (TL) are interventions commonly utilized with individuals with ASD and/or SPD, however, there is limited research on their combined use. The purpose of this study is to determine the effectiveness of the combined occupational therapy (OT) interventions of SD and TL on the occupational performance of children with ASD …

Diagnosis And Management Of Malignant Peripheral Nerve Sheath Tumors: Current Practice And Future Perspectives, Bethany C Prudner, Tyler Ball, Richa Rathore, Angela C Hirbe

2020-Current year OA Pubs

One of the most common malignancies affecting adults with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is the malignant peripheral nerve sheath tumor (MPNST), a highly aggressive sarcoma that typically develops from benign plexiform neurofibromas. Approximately 8-13% of individuals with NF1 will develop MPNST during young adulthood. There are few therapeutic options, and the vast majority of people with these cancers will die within 5 years of diagnosis. Despite efforts to understand the pathogenesis of these aggressive tumors, the overall prognosis remains dismal. This manuscript will review the current understanding of the cellular and molecular progression of MPNST, diagnostic …

Disease And Treatment Patterns Among Patients With Pouch-Related Conditions In A Cohort Of Large Tertiary Care Inflammatory Bowel Disease Centers In The United States, Edward L Barnes, Laura Raffals, Millie D Long, Gaurav Syal, Maia Kayal, Ashwin Ananthakrishnan, Benjamin Cohen, Joel Pekow, Parakkal Deepak, Jean-Frederic Colombel, Hans H Herfarth, Robert S Sandler

2020-Current year OA Pubs

BACKGROUND: Gaps exist in our understanding of the clinical course of pouch-related disorders.

METHODS: We evaluated baseline disease activity and longitudinal treatment patterns among patients with inflammatory conditions of the pouch.

RESULTS: Among 468 patients with an ileal pouch-anal anastomosis (IPAA), 94 (20%) had acute pouchitis, 96 (21%) had chronic pouchitis, and 192 (41%) had Crohn disease of the pouch. Following an IPAA, 38% of patients were treated with a biologic and 11% underwent inflammatory bowel disease- or bowel-related surgery.

CONCLUSIONS: Treatment patterns after IPAA indicate that pouch-related disorders have a significant impact on individual patients and the healthcare system.

On The Nature Of Monozygotic Twin Concordance And Discordance For Autistic Trait Severity: A Quantitative Analysis, Lauren Castelbaum, Chad M Sylvester, Yi Zhang, Qiongru Yu, John N Constantino

2020-Current year OA Pubs

The characterizing features of autism spectrum disorder (ASD) are continuously distributed in nature; however, prior twin studies have not systematically incorporated this knowledge into estimations of concordance and discordance. We conducted a quantitative analysis of twin-twin similarity for autistic trait severity in three existing data sets involving 366 pairs of uniformly-phenotyped monozygotic (MZ) twins with and without ASD. Probandwise concordance for ASD was 96%; however, MZ trait correlations differed markedly for pairs with ASD trait burden below versus above the threshold for clinical diagnosis, with R