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Articles 12961 - 12990 of 310999

Full-Text Articles in Medicine and Health Sciences

How Have We Measured Trial Outcomes Of Asthma Attack Treatment? A Systematic Review, Imran Howell, Aleksandra Howell, Sanjay Ramakrishnan, Mona Bafadhel, Ian Pavord Jan 2024

How Have We Measured Trial Outcomes Of Asthma Attack Treatment? A Systematic Review, Imran Howell, Aleksandra Howell, Sanjay Ramakrishnan, Mona Bafadhel, Ian Pavord

Research outputs 2022 to 2026

Background Asthma attacks are a common problem for people with asthma and are responsible for significant healthcare costs. There is interest in a precision medicine approach to treatment. However, the choice of trial outcome measures for asthma attack treatment is hampered by the absence of a consensus on suitability. We carried out a systematic review to understand the characteristics of outcome measures used in randomised controlled trials of asthma attack treatment. Have randomised controlled trials of asthma attack treatment measured outcomes that are useful to patients and healthcare providers? Methods The protocol was registered on PROSPERO (CRD42022311479). We searched for …


Cross-Sectional Survey Of Staff And Family Perspectives On The Use Of Cctv In Australian Residential Aged Care, Davina Porock, Caroline Vafeas, Mandy Towell-Barnard, Laura Emery, Gemma Doleman, Janine Alan Jan 2024

Cross-Sectional Survey Of Staff And Family Perspectives On The Use Of Cctv In Australian Residential Aged Care, Davina Porock, Caroline Vafeas, Mandy Towell-Barnard, Laura Emery, Gemma Doleman, Janine Alan

Research outputs 2022 to 2026

Objective: To describe staff and family members' opinions about closed-circuit television (CCTV) in communal and private areas of residential aged care facilities (RACF), and to investigate how this relates to perceptions of care quality. Methods: A cross-sectional survey was developed to capture perceptions of CCTV's influence on care quality, and acceptable locations for CCTV placement. Data were recorded as ordinal-scale and open responses. Non-parametric tests of association were conducted. Results: The survey was completed by 81 staff and 74 family members. Both staff and family were satisfied with care quality and safety, irrespective of CCTV use. More family members were …


Enhancing Breast Cancer Treatment: Mesoporous Dopamine Nanoparticles In Synergy With Chrysin For Photothermal Therapy, Jing Zhu, Heng Zhang, Haomiao Lan, Bing Bi, Xianfeng Peng, Dandan Li, Haili Wang, Ke Zhu, Fuqiang Shao, Minggang Yin Jan 2024

Enhancing Breast Cancer Treatment: Mesoporous Dopamine Nanoparticles In Synergy With Chrysin For Photothermal Therapy, Jing Zhu, Heng Zhang, Haomiao Lan, Bing Bi, Xianfeng Peng, Dandan Li, Haili Wang, Ke Zhu, Fuqiang Shao, Minggang Yin

Research outputs 2022 to 2026

Introduction: Breast cancer is one of the most prevalent cancers, primarily affecting women. Among its subtypes, estrogen receptor-positive (ER+) breast cancer is particularly common. Inhibiting estrogen's effects is crucial for treating ER+ breast cancer, but current therapies often have significant side effects and limitations. Chrysin, a natural flavonoid, has shown potential in reducing estrogen receptor expression, but its poor water solubility hampers clinical application. This study explores the use of mesoporous dopamine nanoparticles (mPDA) to enhance the delivery and efficacy of Chrysin, combined with photothermal therapy (PTT), for breast cancer treatment. Methods: Chrysin-loaded mPDA nanoparticles (Chrysin@mPDA) were synthesized and characterized …


Experiences Of The Change Process During Emotion Focused Group Therapy, Jason M. Sharbanee, Kirra Rauchelle, Marina Nelson, Eyal Gringart Jan 2024

Experiences Of The Change Process During Emotion Focused Group Therapy, Jason M. Sharbanee, Kirra Rauchelle, Marina Nelson, Eyal Gringart

Research outputs 2022 to 2026

Emotion Focused Group Therapy has demonstrated preliminary efficacy for multiple syndromes. The groups involve individual chair-work in the context of the group, followed by interpersonal processing of the aroused emotions. So far there has been limited investigation of the mechanisms of change, including participants’ experiences of the change process. This study aimed to qualitatively examine participants’ experiences of the change process during Emotion Focused Group Therapy. Sixteen participants were interviewed about their experiences of the change process during the therapy group. The interview was structured to move from overarching reflections on the process of change, to specific experiences of their …


Impact On Help-Seeking Behaviours Of A Campaign Perceived To Decrease Stigma And Increase Openness Around Mental Health, Robert J. Donovan, Catherine F. Drane, Ziggi I. Santini, Geoffrey Jalleh Jan 2024

Impact On Help-Seeking Behaviours Of A Campaign Perceived To Decrease Stigma And Increase Openness Around Mental Health, Robert J. Donovan, Catherine F. Drane, Ziggi I. Santini, Geoffrey Jalleh

Research outputs 2022 to 2026

Issue Addressed: There is considerable evidence that public stigma around mental illness inhibits help-seeking for mental health problems. Hence there have been many interventions and campaigns designed to reduce stigma around mental illness. However, as far as could be ascertained, none of these stigma reduction interventions has reported any substantial impact of reducing stigma on people's mental health help-seeking behaviours. The aim of this paper is to report on the impact of the Act-Belong-Commit positive mental health promotion Campaign on help-seeking via increasing perceived openness around mental health and reducing perceived stigma around mental illness. Methods: State-wide computer assisted telephone …


Implementing A Gerontological Nursing Competencies Programme In Aged Care: Participant Experiences, Victoria Traynor, Nicole Britten, Diane Gibson, Stephanie Munk, Lynn Chenoweth, Jolan Stokes, Tracey Moroney, Karen Strickland, Toni Donaghy, Kasia Bail Jan 2024

Implementing A Gerontological Nursing Competencies Programme In Aged Care: Participant Experiences, Victoria Traynor, Nicole Britten, Diane Gibson, Stephanie Munk, Lynn Chenoweth, Jolan Stokes, Tracey Moroney, Karen Strickland, Toni Donaghy, Kasia Bail

Research outputs 2022 to 2026

Aims: To explore the experience of registered nurses and their mentors in the implementation of the Gerontological Nursing Competencies in long-term aged care and the perceived effectiveness and suitability of the programme to support nurse development. Background: The global population is ageing and needs a reliable aged-care nursing workforce. Introduction: Opportunities for education and mentorship for newly qualified and experienced aged-care nurses warrant investigation. Methods: Qualitative evaluation using semi-structured focus groups was conducted following the implementation of the programme into five not-for-profit long-term aged-care organisations and analysed by a reflexive qualitative thematic approach and reported according to COREQ criteria. Results: …


Intersectoral Collaboration For Supporting The Health And Wellbeing Of Aboriginal Families And Children In Out-Of-Home Care: Perspectives From Western Australian Aboriginal Community Controlled Health Organisations, Sasha Moodie, Jocelyn Jones, Richard Chenhall, Robyn Williams, Cathy Garlett, Alison Gibberd, Melissa O’Donnell, Dan Mcaullay, Bridgette Mcnamara, Sandra Eades Jan 2024

Intersectoral Collaboration For Supporting The Health And Wellbeing Of Aboriginal Families And Children In Out-Of-Home Care: Perspectives From Western Australian Aboriginal Community Controlled Health Organisations, Sasha Moodie, Jocelyn Jones, Richard Chenhall, Robyn Williams, Cathy Garlett, Alison Gibberd, Melissa O’Donnell, Dan Mcaullay, Bridgette Mcnamara, Sandra Eades

Research outputs 2022 to 2026

Introduction: Western Australia has one of the highest rates of Aboriginal children entering out-of-home care in Australia. Kinship care is the preferred culturally safe out-of-home care option for Aboriginal children, yet all jurisdictions, including Western Australia, are far from meeting best-practice national standards. Intersectoral collaboration is a key primary healthcare principle and internationally recognized for improving health systems and outcomes. This paper presents findings from a qualitative research project investigating Aboriginal primary healthcare workers’ experiences of intersectoral collaboration challenges and strengthening opportunities. Methods: Constructivist grounded theory guided this research involving 55 semi-structured interviews and four focus group discussions with Aboriginal …


It Takes It Out Of The Textbook: Benefits Of And Barriers To Expert By Experience Involvement In Pre-Registration Mental Health Nursing Education, Brenda Happell, Sarah Gordon, John Hurley, Kim Foster, Mike Hazelton, Richard Lakeman, Lorna Moxham, Terri Warner Jan 2024

It Takes It Out Of The Textbook: Benefits Of And Barriers To Expert By Experience Involvement In Pre-Registration Mental Health Nursing Education, Brenda Happell, Sarah Gordon, John Hurley, Kim Foster, Mike Hazelton, Richard Lakeman, Lorna Moxham, Terri Warner

Research outputs 2022 to 2026

What Is Known on the Subject?: Service user involvement in mental health nursing education is beneficial in terms of attitudinal change to reduce stigma, clinical skill development and enhancing understandings of recovery-oriented practice. Service users as experts by experience have not been embedded within pre-registration nursing programs. Consequently, they remain limited in number, ad hoc and frequently tokenistic. Nurse academics responsible for the design and delivery of pre-registration mental health nursing curricula have a potentially important role in facilitating expert by experience involvement in mental health nursing education. What this Paper Adds to Existing Knowledge: Nurse academics teaching mental health …


It's Day To Day Problems: Experiences Of People With Aphasia Who Live Alone, Deborah Hersh, Clare Williamson, Emily Brogan, Mandy Stanley Jan 2024

It's Day To Day Problems: Experiences Of People With Aphasia Who Live Alone, Deborah Hersh, Clare Williamson, Emily Brogan, Mandy Stanley

Research outputs 2022 to 2026

Purpose: Living alone is increasing and associated with health and social risks. Aphasia compounds these risks but there is little research on how living alone interacts with aphasia. This study is a preliminary exploration of this issue. Method: Five people with aphasia who lived alone participated in two supported semi-structured interviews, with the second interview including sharing an artefact that held significance for living alone with aphasia. Interviews were recorded, transcribed verbatim, and analysed through reflexive thematic analysis. Result: Four themes encompassed meaning-making about living alone with aphasia: relationships and reliance on others; risk, vulnerability, and uncertainty; loneliness and time …


Motoneuron Persistent Inward Current Contribution To Increased Torque Responses To Wide-Pulse High-Frequency Neuromuscular Electrical Stimulation, Timothée Popesco, Lucas Bet Da Rosa Orssatto, François Hug, Anthony John Blazevich, Gabriel Siqueira Trajano, Nicolas Place Jan 2024

Motoneuron Persistent Inward Current Contribution To Increased Torque Responses To Wide-Pulse High-Frequency Neuromuscular Electrical Stimulation, Timothée Popesco, Lucas Bet Da Rosa Orssatto, François Hug, Anthony John Blazevich, Gabriel Siqueira Trajano, Nicolas Place

Research outputs 2022 to 2026

Purpose: To assess the effect of a remote handgrip contraction during wide-pulse high-frequency (WPHF) neuromuscular electrical stimulation (NMES) on the magnitude of extra torque, progressive increase in torque during stimulation, and estimates of the persistent inward current (PIC) contribution to motoneuron firing in the plantar flexors. Methods: Ten participants performed triangular shaped contractions to 20% of maximal plantar flexion torque before and after WPHF NMES with and without a handgrip contraction, and control conditions. Extra torque, the relative difference between the initial and final torque during stimulation, and sustained electromyographic (EMG) activity were assessed. High-density EMG was recorded during triangular …


Music As A Determinant Of Health Among First Nations People In Australia: A Scoping Narrative Review, Brigitta Scarfe, Kristy Apps, Naomi Sunderland, Phil Graham, Brydie Leigh Bartleet, Glenn Barry, Darren Garvey, Rae Cooper, Clint Bracknell Jan 2024

Music As A Determinant Of Health Among First Nations People In Australia: A Scoping Narrative Review, Brigitta Scarfe, Kristy Apps, Naomi Sunderland, Phil Graham, Brydie Leigh Bartleet, Glenn Barry, Darren Garvey, Rae Cooper, Clint Bracknell

Research outputs 2022 to 2026

Issue Addressed: While social determinants frameworks are still popular in research about First Nations health in Australia, a growing body of research prefers cultural determinants of health models. Cultural determinants models provide a holistic, strength-based framework to explain connections between health and contextual factors, including the potential role of music and its impact on social and emotional well-being. Given the growing international recognition of links between music, health, and wellbeing through bodies such as the World Health Organisation, this article examines whether and how music practices are acknowledged in First Nations determinants of health literature. Methods: We conducted a scoping …


Nurse By Numbers: The Impact Of Early Warning Systems On Nurses' Higher-Order Thinking, A Quantitative Study, Marie Danielle Le Lagadec, Deb Massey, Amy Louise Byrne, Justine Connor, Tracy Flenady Jan 2024

Nurse By Numbers: The Impact Of Early Warning Systems On Nurses' Higher-Order Thinking, A Quantitative Study, Marie Danielle Le Lagadec, Deb Massey, Amy Louise Byrne, Justine Connor, Tracy Flenady

Research outputs 2022 to 2026

Aim: To evaluate registered nurses' perceptions of whether the mandated use of the early warning system vital signs tool impacts the development of nurses' higher-order thinking skills. Design: A concurrent mixed methods study design. Method: Using an online survey, registered nurses' perceptions were elucidated on whether early warning system algorithmic tools affected the development of their higher-order thinking. Likert-type matrix questions with additional qualitative fields were used to obtain information on nurse's perceptions of the tool's usefulness, clinical confidence in using the tool, compliance with escalation protocols, work environment and perceived compliance barriers. Results: Most of the 305 (91%) participants …


Nursing Assessment Of Mental Health Issues In The General Clinical Environment: A Descriptive Study, Irene Ngune, Beverley Ewens, Sharlene Bell, Brendon Burns, Claire Sutton, Craig Creswell, Yvonne Middlewick Jan 2024

Nursing Assessment Of Mental Health Issues In The General Clinical Environment: A Descriptive Study, Irene Ngune, Beverley Ewens, Sharlene Bell, Brendon Burns, Claire Sutton, Craig Creswell, Yvonne Middlewick

Research outputs 2022 to 2026

Aims: To evaluate the effectiveness of a mental health screening form for early identification and care escalation of mental health issues in general settings. A secondary aim was to explore general nurses' use of the form and their confidence to discuss mental health issues with patients. Methods: A cross-sectional design comprising a review of clinical records to determine use of the form, instances of missed care and escalation to the mental health team. The survey focused on nurses' confidence in general settings to engage in discussions with patients about mental health. Data were collected from April to December 2022. The …


Nursing/Midwifery Students' Perceptions Of Caring Pedagogy And Online Learning During The Covid-19 Pandemic, Rikki Jones, Debra Jackson, Kylie Rice, Murray Fisher, Pauline Callega, Martin Hopkins, Caryn West, Pauletta Irwin, Shirley Mcgough, Lauretta Luck, Felicity Walker, Nicola Whiteing, Kim Usher Jan 2024

Nursing/Midwifery Students' Perceptions Of Caring Pedagogy And Online Learning During The Covid-19 Pandemic, Rikki Jones, Debra Jackson, Kylie Rice, Murray Fisher, Pauline Callega, Martin Hopkins, Caryn West, Pauletta Irwin, Shirley Mcgough, Lauretta Luck, Felicity Walker, Nicola Whiteing, Kim Usher

Research outputs 2022 to 2026

Aim: This study aimed to gain a better understanding of nursing/midwifery students' perspectives on a pedagogy of caring and online learning during the COVID-19 pandemic. In addition, it aimed to determine if the COVID-19 pandemic impacted students' perceptions and experience of online learning and students' desire to enter the nursing/midwifery workforce. Design: Mixed methods. Methods: A multi-centre cross-sectional survey of Australian nursing and midwifery students was undertaken to explore students’ experience of learning during the COVID-19 pandemic. Results: There are several key findings from this study that may be relevant for the future delivery of undergraduate health education, students transitioning …


Physiological Plateaus During Normal Labor And Birth: A Novel Definition, Marina Weckend, Kylie Mccullough, Christine Duffield, Sara Bayes, Clare Davison Jan 2024

Physiological Plateaus During Normal Labor And Birth: A Novel Definition, Marina Weckend, Kylie Mccullough, Christine Duffield, Sara Bayes, Clare Davison

Research outputs 2022 to 2026

Background: Diagnoses of labor dystocia, and subsequent labor augmentation, make one of the biggest contributions to childbirth medicalization, which remains a key challenge in contemporary maternity care. However, labor dystocia is poorly defined, and the antithetical concept of physiological plateaus remains insufficiently explored. Aim: To generate a definition of physiological plateaus as a basis for further research. Methods: This qualitative study applied grounded theory methods and comprised interviews with 20 midwives across Australia, conducted between September 2020 and February 2022. Data were coded in a three-phase approach, starting with inductive line-by-line coding, which generated themes and subthemes, and finally, through …


Psychedelic Trip Sitting, Dosages And Intensities: Supplementing Clinical Studies With Anecdotal Reports, Liam B. Engel, Sascha Thal, Stephen J. Bright, Mitchell Low Jan 2024

Psychedelic Trip Sitting, Dosages And Intensities: Supplementing Clinical Studies With Anecdotal Reports, Liam B. Engel, Sascha Thal, Stephen J. Bright, Mitchell Low

Research outputs 2022 to 2026

Background and aims: Online communities provide insights into psychedelic consumption, assisting in identification of trends, informing both harm reduction provisions and clinical research. This study extracts forum data on psychedelic substances, dosages, and administration routes, categorising and analysing self-reported consumption to inform care services and guide clinical work with psychedelics. Methods: Posts (n = 660) from online psychedelic forums (The Shroomery and DMT Nexus) on 'trip sitting' were analysed. Using a Delphi-style expert panel review facilitated by LE, we created drug weight and intensity charts (threshold, light, common, strong and heavy dosages) for psychedelics discussed in these posts. The psychedelic …


Pulmonary Embolism Response Teams. A Description Of The First 36-Month Australian Experience, Bapti Roy, Jin Gun Cho, Luke Baker, Liza Thomas, Jennifer Curnow, John J. Harvey, Paul Geenty, Ashoke Banerjee, Kevin Lai, Mauro Vicaretti, Odette Erksine, Jane Li, Rafid Alasady, Vanessa Wong, Jian E. Tai, Caitlin Thirunavukarasu, Imran Haque, Jimmy Chien Jan 2024

Pulmonary Embolism Response Teams. A Description Of The First 36-Month Australian Experience, Bapti Roy, Jin Gun Cho, Luke Baker, Liza Thomas, Jennifer Curnow, John J. Harvey, Paul Geenty, Ashoke Banerjee, Kevin Lai, Mauro Vicaretti, Odette Erksine, Jane Li, Rafid Alasady, Vanessa Wong, Jian E. Tai, Caitlin Thirunavukarasu, Imran Haque, Jimmy Chien

Research outputs 2022 to 2026

Background: High/intermediate-risk pulmonary embolism (PE) confers increased risk of cardiovascular morbidity and mortality. International guidelines recommend the formation of a PE response team (PERT) for PE management because of the complexity of risk stratification and emerging treatment options. However, there are currently no available Australian data regarding outcomes of PE managed through a PERT. Aims: To analyse the clinical and outcome data of patients from an Australian centre with high/intermediate-risk PE requiring PERT-guided management. Methods: We performed a retrospective observational study of 75 consecutive patients with high/intermediate-risk PE who had PERT involvement, between August 2018 and July 2021. We recorded …


Rationale, Design, And Baseline Characteristics Of Participants In The Health@Nus Mhealth Augmented Cohort Study Examining Student-To-Work Life Transition: Protocol For A Prospective Cohort Study, Xin Hui Chua, Sarah Martine Edney, Andre Matthias Müller, Nicholas A. Petrunoff, Clare Whitton, Zoey Tay, Claire Marie Jie Lin Goh, Bozhi Chen, Su Hyun Park, Salome A. Rebello, Alicia Low, Janelle Chia, Daphne Koek, Karen Cheong, Rob M. Van Dam, Falk Müller-Riemenschneider Jan 2024

Rationale, Design, And Baseline Characteristics Of Participants In The Health@Nus Mhealth Augmented Cohort Study Examining Student-To-Work Life Transition: Protocol For A Prospective Cohort Study, Xin Hui Chua, Sarah Martine Edney, Andre Matthias Müller, Nicholas A. Petrunoff, Clare Whitton, Zoey Tay, Claire Marie Jie Lin Goh, Bozhi Chen, Su Hyun Park, Salome A. Rebello, Alicia Low, Janelle Chia, Daphne Koek, Karen Cheong, Rob M. Van Dam, Falk Müller-Riemenschneider

Research outputs 2022 to 2026

Background: Integration of mobile health data collection methods into cohort studies enables the collection of intensive longitudinal information, which gives deeper insights into individuals’ health and lifestyle behavioral patterns over time, as compared to traditional cohort methods with less frequent data collection. These findings can then fill the gaps that remain in understanding how various lifestyle behaviors interact as students graduate from university and seek employment (student-to-work life transition), where the inability to adapt quickly to a changing environment greatly affects the mental well-being of young adults. Objective: This paper aims to provide an overview of the study methodology and …


Resting Heart Rate And Risk Of Dementia: A Mendelian Randomization Study In The International Genomics Of Alzheimer’S Project And Uk Biobank, Xingxing Chen, Yi Zheng, Jun Wang, Blake Yue, Xian Zhang, Kenta Nakai, Lijing L. Yan Jan 2024

Resting Heart Rate And Risk Of Dementia: A Mendelian Randomization Study In The International Genomics Of Alzheimer’S Project And Uk Biobank, Xingxing Chen, Yi Zheng, Jun Wang, Blake Yue, Xian Zhang, Kenta Nakai, Lijing L. Yan

Research outputs 2022 to 2026

Background: Observational studies have demonstrated that a higher resting heart rate (RHR) is associated with an increased risk of dementia. However, it is not clear whether the association is causal. This study aimed to determine the causal effects of higher genetically predicted RHR on the risk of dementia. Methods: We performed a two-sample Mendelian randomization analysis to investigate the causal effect of higher genetically predicted RHR on Alzheimer’s disease (AD) using summary statistics from genome-wide association studies. The generalized summary Mendelian randomization (GSMR) analysis was used to analyze the corresponding effects of RHR on following different outcomes: 1) diagnosis of …


Role Of Short Chain Fatty Acids On Astrocytes And Microglia In Alzheimer's Disease Brain, Rathnayaka Mudiyanselage Uththara Sachinthanie Senarath, Matthew Burton, Welisarage Mary Kendrea Thiasangee Fernando, Vijay Jayasena, Charles Brennan, Wanakulasuriya Mary Ann Dipika Binosha Fernando Jan 2024

Role Of Short Chain Fatty Acids On Astrocytes And Microglia In Alzheimer's Disease Brain, Rathnayaka Mudiyanselage Uththara Sachinthanie Senarath, Matthew Burton, Welisarage Mary Kendrea Thiasangee Fernando, Vijay Jayasena, Charles Brennan, Wanakulasuriya Mary Ann Dipika Binosha Fernando

Research outputs 2022 to 2026

Short-chain fatty acids (SCFAs) hold exert many nutritional benefits on both physiological and pathological processes, including host metabolism, immune modulation, and appetite control. Originating from the microbial fermentation of resistant starches and dietary fibre in the colon, SCFAs have the capability to traverse the blood–brain barrier (BBB). It is evident that SCFAs play a critical role in the development of neurodegenerative disorders such as Alzheimer's disease (AD). AD is the most common form of dementia and is characterised by the deposition of amyloid β peptides (Aβ) and tau hyperphosphorylation. SCFAs have demonstrated the potential to interfere with the protein–protein interactions …


Seven-Day Dietary Nitrate Supplementation Clinically Significantly Improves Basal Macrovascular Function In Postmenopausal Women: A Randomized, Placebo-Controlled, Double-Blind, Crossover Clinical Trial, Jocelyn M. Delgado Spicuzza, Jigar Gosalia, Liezhou Zhong, Catherine Bondonno, Kristina S. Petersen, Mary Jane De Souza, Elmira Alipour, Daniel B. Kim-Shapiro, Yasina B. Somani, David N. Proctor Jan 2024

Seven-Day Dietary Nitrate Supplementation Clinically Significantly Improves Basal Macrovascular Function In Postmenopausal Women: A Randomized, Placebo-Controlled, Double-Blind, Crossover Clinical Trial, Jocelyn M. Delgado Spicuzza, Jigar Gosalia, Liezhou Zhong, Catherine Bondonno, Kristina S. Petersen, Mary Jane De Souza, Elmira Alipour, Daniel B. Kim-Shapiro, Yasina B. Somani, David N. Proctor

Research outputs 2022 to 2026

Introduction: Cardiovascular disease (CVD) is the leading cause of death in women, with increased risk following menopause. Dietary intake of beetroot juice and other plant-based nitrate-rich foods is a promising non-pharmacological strategy for increasing systemic nitric oxide and improving endothelial function in elderly populations. The purpose of this randomized, placebo-controlled, double-blind, crossover clinical trial was to determine the effects of short-term dietary nitrate (NO3−) supplementation, in the form of beetroot juice, on resting macrovascular endothelial function and endothelial resistance to whole-arm ischemia–reperfusion (IR) injury in postmenopausal women at two distinct stages of menopause. Methods: Early-postmenopausal [1–6 years following their final …


Sleep Discrepancy And Cognitive Function In Community-Dwelling Older Adults, Nadia Soh, Stephanie R. Rainey-Smith, James D. Doecke, Rodrigo Canovas, Romola S. Bucks, Melissa Ree, Michael Weinborn Jan 2024

Sleep Discrepancy And Cognitive Function In Community-Dwelling Older Adults, Nadia Soh, Stephanie R. Rainey-Smith, James D. Doecke, Rodrigo Canovas, Romola S. Bucks, Melissa Ree, Michael Weinborn

Research outputs 2022 to 2026

This was the first study to use cluster analysis to characterise sleep discrepancy (the discordance between self-reported and objective sleep) across multiple sleep parameters, in community-dwelling older adults. For sleep efficiency, negative discrepancy (the tendency to self-report worse sleep than objectively-measured) was associated with poorer memory, independent of insomnia severity, depressive symptoms and objective sleep. This suggests a unique role for sleep discrepancy as a possible risk factor for future cognitive decline, and warrants the need for further research.


The Impact Of Mandated Use Early Warning System Tools On The Development Of Nurses' Higher-Order Thinking: A Systematic Review, Tracy Flenady, Justine Connor, Amy Louise Byrne, Deb Massey, Marie Danielle Le Lagadec Jan 2024

The Impact Of Mandated Use Early Warning System Tools On The Development Of Nurses' Higher-Order Thinking: A Systematic Review, Tracy Flenady, Justine Connor, Amy Louise Byrne, Deb Massey, Marie Danielle Le Lagadec

Research outputs 2022 to 2026

Aim: Ascertain the impact of mandated use of early warning systems (EWSs) on the development of registered nurses' higher-order thinking. Design: A systematic literature review was conducted, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and checklist (Page et al., 2021). Data Sources: CINAHL, Medline, Embase, PyscInfo. Review Methods: Eligible articles were quality appraised using the MMAT tool. Data extraction was conducted independently by four reviewers. Three investigators thematically analysed the data. Results: Our review found that EWSs can support or suppress the development of nurses' higher-order thinking. EWS supports the development of higher-order thinking in two …


The Influence Of Culture On The Health Beliefs And Health Behaviours Of Older Vietnam-Born Australians Living With Chronic Disease, Thi Ngoc Minh Nguyen, Rosemary Saunders, Gordana Dermody, Lisa Whitehead Jan 2024

The Influence Of Culture On The Health Beliefs And Health Behaviours Of Older Vietnam-Born Australians Living With Chronic Disease, Thi Ngoc Minh Nguyen, Rosemary Saunders, Gordana Dermody, Lisa Whitehead

Research outputs 2022 to 2026

Aim: To explore the health beliefs and health behaviours of older Vietnam-born people living with chronic disease in Western Australia. Design: This study was designed as a focused ethnography guided by the interpretative research paradigm and Leininger's Theory of Culture Care. Methods: Data were collected through participant observation and interviews undertaken at participants' homes in Western Australia over 7 months in 2019. Data were analysed using Wolcott's approach for transferring qualitative data, comprising three phases: description, thematic analysis and interpretation. Results: This study included 12 participants. The health perspectives and practices of older Vietnam-born Australians significantly reflected the traditional Vietnamese …


The Relationship Between Moral Thought-Action Fusion And Scrupulosity Across Judaism, Christianity, And Islam, Kelsey Evey Jan 2024

The Relationship Between Moral Thought-Action Fusion And Scrupulosity Across Judaism, Christianity, And Islam, Kelsey Evey

Graduate Theses, Dissertations, and Problem Reports

Scrupulosity is a subtype of obsessive-compulsive disorder (OCD) where individuals are upset by intrusive thoughts related to religious or moral issues. Current research suggests that scrupulosity occurs across the major world religions—including the Abrahamic religions (i.e., Judaism, Christianity, and Islam). Some research suggests that moral thought-action fusion (moral TAF), a dysfunctional belief that thinking something is equal to doing it, may only be pathological under certain circumstances (e.g., if it is not culturally normative). If this is true, the current cognitive model of scrupulosity may need to be amended to reflect how cultural differences impact the role of moral TAF …


Self-Efficacy And Parental Miscarried Helping In Adherence And Transition Readiness Among Adolescents And Young Adults With Epilepsy, Kirby-Estar G. Laguerre Jan 2024

Self-Efficacy And Parental Miscarried Helping In Adherence And Transition Readiness Among Adolescents And Young Adults With Epilepsy, Kirby-Estar G. Laguerre

Graduate Theses, Dissertations, and Problem Reports

Background: Given the complex regimen associated with epilepsy, ensuring that adolescents and young adults (AYAs) adhere to their medications, and are ready to transition from pediatric to adult care, is crucial to optimizing their health outcomes. Several social and ecological factors such as self-efficacy and parental miscarried helping can strengthen or weaken an adolescent’s medication adherence and readiness to shift from pediatric to adult care. Intending to contribute to informing and improving clinical care, this study sought to understand the relationships between self-efficacy, parental miscarried helping, medication adherence, and transition readiness. Methods: Using a cross-sectional observational design, 46 AYAs with …


Associations Among Psychosocial Factors, Health-Related Quality Of Life, And Adherence In Pediatric Inflammatory Bowel Disease, Cecelia I. Nelson Jan 2024

Associations Among Psychosocial Factors, Health-Related Quality Of Life, And Adherence In Pediatric Inflammatory Bowel Disease, Cecelia I. Nelson

Graduate Theses, Dissertations, and Problem Reports

Inflammatory Bowel Disease (IBD) is a prevalent disorder among youth in the United States. IBD is one of the leading causes of chronic pain in adolescence and symptoms can lead to reduced quality of life, social embarrassment, and lower self-esteem. Adherence to medical regimens for IBD is incredibly important to prevent morbidity, mortality, and impaired health-related quality of life (HRQOL). However, adolescents struggle generally with adherence and the regimen for IBD can be complicated and include aversive side effects. Psychological factors, such as depressive symptoms, are key factors associated with non-adherence. Nevertheless, gut-specific anxiety (GSA) is a psychological factor that …


Implant Overdenture Abutment Loosening Under Hyperbaric Conditions, Zana Jamal Al-Saloum Jan 2024

Implant Overdenture Abutment Loosening Under Hyperbaric Conditions, Zana Jamal Al-Saloum

Graduate Theses, Dissertations, and Problem Reports

Objectives: To investigate the effect of various hyperbaric air pressures on the loosening of LOCATOR® (ZEST Anchors, LLC, Escondido, CA USA) overdenture abutments.

The pressure conditions tested are meant to simulate scuba diving conditions in edentulous patients that are restored with implant-retained tissue-supported overdentures. Another sub-goal of this study is to determine whether or not there is a difference in LOCATOR® loosening when the sample is exposed to six cycles/dives as opposed to one cycle/dive.

Methods: 36 ZimVie Tapered Screw Vent Implants with a 3.5mm diameter implant platform, and a 2.5mm diameter (and 1.5mm deep) internal hexagon were …


Assessing The Impact Of Olive Oil And Flaxseed Oil Supplementation On Hypertension And Inflammation In Healthy And At-Risk Adults, Tara Bess Mcnabb Jan 2024

Assessing The Impact Of Olive Oil And Flaxseed Oil Supplementation On Hypertension And Inflammation In Healthy And At-Risk Adults, Tara Bess Mcnabb

Graduate Theses, Dissertations, and Problem Reports

Background: Supplementation of olive oil and flaxseed oil and their impacts on hypertension and inflammation have been reported for healthy and hypertensive adults. However, a comprehensive systematic literature review and meta-analysis on the preventive benefit of plant oil supplementation in healthy adults and adults at risk of inflammation inducing hypertension is lacking.

Objective: to evaluate human clinical trials assessing the impact of olive oil and flaxseed oil capsules on systolic blood pressure (SBP) and diastolic blood pressure (DBP) and select inflammatory markers in non-hypertensive and at-risk adults of hypertension.

Data sources: Four databases were searched in October 2023 …


Usage Of Peer Mentoring Workbooks: Enhancing The Transition Of College Students With Intellectual And Developmental Disabilities, Taylor Nicole Grout Jan 2024

Usage Of Peer Mentoring Workbooks: Enhancing The Transition Of College Students With Intellectual And Developmental Disabilities, Taylor Nicole Grout

Graduate Theses, Dissertations, and Problem Reports

This doctoral capstone project assesses the impact and effectiveness of using peer mentoring workbooks as a tool to enhance the transition of college students with intellectual and developmental disabilities. A peer mentoring workbook was developed using theoretical frameworks to guide its design and identification of primary occupations, roles, and routines of college students. From here, four domains of college student life (dorm living, college social life, classroom management and participation, and community engagement and transportation) were developed to act as a framework for the workbook. Through the usage of Participatory Action Research, key stakeholders provided essential feedback that allowed for …