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Articles 12931 - 12960 of 325136

Full-Text Articles in Medicine and Health Sciences

Exploring The Relationship Between Bmi Classification And Levels Of Food Noise, Edmarie Billosillo Jan 2026

Exploring The Relationship Between Bmi Classification And Levels Of Food Noise, Edmarie Billosillo

Loma Linda University Research Reports

Rising rates of obesity in the United States necessitates an understanding of the multitude of factors that contribute to it. Recently, “food noise” has emerged as a topic of interest in this space. The current survey-based observational study aimed to understand the relationship between Body Mass Index (BMI) and levels of food noise. The results indicate a significant association between BMI and food noise levels and a connection between a history of disordered eating and food noise levels. Additionally scores on the Food Noise Questionnaire (FNQ) and the Food Cravings Questionnaire - Trait – reduced (FCQ-R-r) were found to be …


Dual Orexin Receptor Antagonism With Lemborexant Enhances Microglial Clearance Of Β-Amyloid In Mice, Ashish Sharma, Emiko Segawa, Xiaoying Chen, Sohui Park, Shoutang Wang, Riley E. Irmen, Nicholas J. Constantino, Chanung Wang, Michael F. Kanan, Marco Colonna, Shannon L. Macauley, Jocelyn Y. Cheng, Ken Hatanaka, Margaret Moline, Erik S. Musiek Jan 2026

Dual Orexin Receptor Antagonism With Lemborexant Enhances Microglial Clearance Of Β-Amyloid In Mice, Ashish Sharma, Emiko Segawa, Xiaoying Chen, Sohui Park, Shoutang Wang, Riley E. Irmen, Nicholas J. Constantino, Chanung Wang, Michael F. Kanan, Marco Colonna, Shannon L. Macauley, Jocelyn Y. Cheng, Ken Hatanaka, Margaret Moline, Erik S. Musiek

Sanders-Brown Center on Aging Faculty Publications

Background: Sleep disturbances elevate brain amyloid-beta (Aβ) levels and represent a modifiable risk factor for Alzheimer’s disease (AD). The orexin/hypocretin system regulates sleep–wake behavior and has emerged as a therapeutic target in AD; however, the effects of FDA-approved dual orexin receptor antagonists (DORAs) on amyloid pathology remain unclear. We compared lemborexant, an FDA-approved DORA, to doxepin, an antihistaminergic sleep medication, on amyloid pathology and microglial responses in PSAPP mice.

Methods: PSAPP mice received lemborexant (10 or 30 mg/kg/day), doxepin (35 mg/kg/day), or vehicle for 6 weeks beginning prior to plaque onset or 4 weeks after established pathology. Sleep was assessed …


The Effects Of Vestibular Dysfunction On Cognition, Sai Puneeth Kothuru Jan 2026

The Effects Of Vestibular Dysfunction On Cognition, Sai Puneeth Kothuru

Honors Theses

Virtual Reality (VR) systems are being used more in education, entertainment, and research, but can produce motion sickness that could temporarily disrupt cognitive functioning. This study examined whether exposure to a VR roller coaster experience leads to short-term changes in cognitive flexibility, attention, spatial orientation awareness, and anxiety compared to a control condition. Participants were randomly assigned to a VR condition or a computer-based 2D viewing condition with identical roller coaster visual content. Participants completed three testing blocks: baseline, after exposure, and after a 10-minute recovery period. Cognitive flexibility and attention were assessed using the Trail Making Test (TMT), and …


Microgravity-Induced Alterations In Left Atrial Hemodynamics And Thrombogenic Risk: Insights From Healthy And Atrial Fibrillation Models, Grace M. Hoeppner Jan 2026

Microgravity-Induced Alterations In Left Atrial Hemodynamics And Thrombogenic Risk: Insights From Healthy And Atrial Fibrillation Models, Grace M. Hoeppner

Dissertations, Master's Theses and Master's Reports

Background: Microgravity exposure alters cardiovascular loading, yet its impact on left atrial flow dynamics and thrombotic risk remains poorly understood. This study investigates how spaceflight-relevant microgravity-induced changes in cardiac outflow affect left atrial hemodynamics in healthy individuals and patients with atrial fibrillation.

Methods: Patient-specific left atrial models were generated for three healthy individuals and three AF patients. Computational fluid dynamics (CFD) simulations were performed using each patient’s baseline mitral outflow waveform and two modified waveforms representing short- and long-duration post-flight cardiac loading changes derived from echocardiographic observations. Hemodynamic metrics included left atrial velocity, time averaged wall shear stress, oscillatory shear …


Effect Of Canagliflozin Pretreatment On The Efficacy Of Insulin Therapy To Rescue Type 1 Diabetes-Related Bone Fragility In Male Mice, Jeffry S. Nyman, R. Clay Bunn, Sasidhar Uppuganti, Elizabeth M. Hennen, Plaban Mishra, Philip D. Ray, Anthony Garcia Mendez, Evangelia Kalaitzoglou, John L. Fowlkes Jan 2026

Effect Of Canagliflozin Pretreatment On The Efficacy Of Insulin Therapy To Rescue Type 1 Diabetes-Related Bone Fragility In Male Mice, Jeffry S. Nyman, R. Clay Bunn, Sasidhar Uppuganti, Elizabeth M. Hennen, Plaban Mishra, Philip D. Ray, Anthony Garcia Mendez, Evangelia Kalaitzoglou, John L. Fowlkes

Barnstable Brown Diabetes Center Faculty Publications

Humans with type 1 diabetes (T1D) have a higher-than-expected fracture risk, and bone is weak in mouse models of T1D. Since hyperglycemia is thought to deleteriously affect tissue-level sensitivity of insulin action, we hypothesized that glucose-lowering by canagliflozin (Cana) improves the ability of insulin treatment to rescue the T1D-related decrease in bone strength. To test this hypothesis, male DBA/2 mice with and without streptozotocin (STZ)-induced hyperglycemia at 8 weeks of age were fed a diet with and without Cana (50 ppm) at 10 weeks of age and then the T1D mice, regardless of placebo diet or Cana diet, were treated …


Emergency Department-Initiated Standard Versus High-Dose Buprenorphine Induction (Envision): A Randomised Clinical Trial Protocol, Kathryn Hawk, Andrew Herring, Marek Chawarski, Erik S. Anderson, Michael Baumann, Alyrene Dorey, August F. Holtyn, Christopher Jones, Shara Martel, Patricia Owens, Kaitlin Kmiecik, Tania D. Strout, Peter Taillac, Michelle R. Lofwall, Sharon L. Walsh, Gail D’Onofrio Jan 2026

Emergency Department-Initiated Standard Versus High-Dose Buprenorphine Induction (Envision): A Randomised Clinical Trial Protocol, Kathryn Hawk, Andrew Herring, Marek Chawarski, Erik S. Anderson, Michael Baumann, Alyrene Dorey, August F. Holtyn, Christopher Jones, Shara Martel, Patricia Owens, Kaitlin Kmiecik, Tania D. Strout, Peter Taillac, Michelle R. Lofwall, Sharon L. Walsh, Gail D’Onofrio

Center on Drug and Alcohol Research Faculty Publications

Introduction: The initiation of buprenorphine for patients with opioid use disorder (OUD) in the emergency department (ED) has been associated with improved outcomes including reduced ED visits and increased treatment engagement. Though both standard-dose (8 mg buprenorphine equivalent) and high-dose (24 mg buprenorphine equivalent) strategies to initiate buprenorphine have been used in the ED, no prospective trials comparing outcomes among patients receiving these treatments have been reported.

Methods and analysis: This multisite randomised clinical trial is a multisite double-blind, double-dummy, randomised clinical trial enrolling 360 emergency department patients with moderate-to-severe OUD. Enrolled patients will be randomised to one of two …


Facebook As A Strategy To Deliver A Peer Navigation Intervention For Recently Incarcerated Women With Opioid Use Disorder: A Mixed Methods Descriptive Profile, Martha Tillson, Jaxin Annett, Marguerite A. Webster, Amanda Fallin-Bennett, Mandi Webster, Amber Clemons, Cynthia Robinson, Kevin Crabtree, Casey Baker-Romans, Michele Staton Jan 2026

Facebook As A Strategy To Deliver A Peer Navigation Intervention For Recently Incarcerated Women With Opioid Use Disorder: A Mixed Methods Descriptive Profile, Martha Tillson, Jaxin Annett, Marguerite A. Webster, Amanda Fallin-Bennett, Mandi Webster, Amber Clemons, Cynthia Robinson, Kevin Crabtree, Casey Baker-Romans, Michele Staton

Center on Drug and Alcohol Research Faculty Publications

Recovery support and treatment linkages are critical during transitions from incarceration to community but can be challenging to deliver to hard-to-reach populations. This paper will examine Facebook contacts between peer navigators (PNs) and women with opioid use disorder (OUD) following jail release to explore women’s use of PN services, including purpose and content of Facebook messages. As part of a larger clinical trial under the Justice Community Opioid Innovation Network (JCOIN), PNs provided OUD treatment navigation and recovery support for 12 weeks following women’s release from jail, using remote options such as Facebook. Facebook Messenger transcripts between PNs and participants …


Evolution Of A Client‐Level Dataset: 20 Years Of National Child Traumatic Stress Network Data Collection, C. A. Purbeck, A. N. Cooke, L. J. Liang, C. Smith, J. Staten, J. Epstein, H. B. Hodgdon, Jessica Eslinger, A. Wells, J. Goodrich, T. H. Bethel, K. Willett, Y. C. Fu, J. A. Fairbank, E. C. Briggs Jan 2026

Evolution Of A Client‐Level Dataset: 20 Years Of National Child Traumatic Stress Network Data Collection, C. A. Purbeck, A. N. Cooke, L. J. Liang, C. Smith, J. Staten, J. Epstein, H. B. Hodgdon, Jessica Eslinger, A. Wells, J. Goodrich, T. H. Bethel, K. Willett, Y. C. Fu, J. A. Fairbank, E. C. Briggs

Center on Trauma and Children Faculty Publications

Objectives: For 20 years, the National Child Traumatic Stress Network's (NCTSN) data collection efforts have been a central mechanism for Clinical Quality Improvement (ClQI). The NCTSN is a federally funded initiative in the United States composed of programs dedicated to raising the standard of care and increasing access to services for children and families who have experienced traumatic events.

Methods: These efforts span three initiatives: the Core Data Set (CDS), the Clinical Improvement through Measurement Initiative (CIMI) Measurement Based Care (MBC), and CIMI Data Sharing (CIMI-DS) that collected and analyzed client-level data to improve care for children and families served …


ผลของโปรแกรมการมีส่วนร่วมในการดูแลเด็กที่มีไข้สูงต่อความพึงพอใจของผู้ดูแล หอผู้ป่วยเด็ก โรงพยาบาลศิครินทร์ กรุงเทพมหานคร, ธัญญพัทธ์ นิธิชัยพัฒนากิจ, วณัฐธมนต์ เจริญสิงห์, นันทนา ยะแสง, กัญญดา ประจุศิลป, นรลักขณ์ เอื้อกิจ Jan 2026

ผลของโปรแกรมการมีส่วนร่วมในการดูแลเด็กที่มีไข้สูงต่อความพึงพอใจของผู้ดูแล หอผู้ป่วยเด็ก โรงพยาบาลศิครินทร์ กรุงเทพมหานคร, ธัญญพัทธ์ นิธิชัยพัฒนากิจ, วณัฐธมนต์ เจริญสิงห์, นันทนา ยะแสง, กัญญดา ประจุศิลป, นรลักขณ์ เอื้อกิจ

Journal of Nursing Research, Innovation, and Health

วัตถุประสงค์ : เพื่อศึกษาผลของโปรแกรมการมีส่วนร่วมในการดูแลเด็กที่มีไข้สูงต่อความพึงพอใจของผู้ดูแล หอผู้ป่วยเด็ก โรงพยาบาลศิครินทร์ กรุงเทพมหานคร

แบบแผนงานวิจัย : การวิจัยแบบกึ่งทดลอง แบบศึกษาสองกลุ่มวัดครั้งเดียว

วิธีดำเนินการวิจัย : กลุ่มตัวอย่างเป็นผู้ดูแลอายุ 20 ปีขึ้นไป ที่รับผิดชอบดูแลผู้ป่วยเด็กที่มีอาการสำคัญในการมาโรงพยาบาลด้วยมีไข้สูง อุณหภูมิกายมากกว่า 38.5 องศาเซลเซียส ซึ่งเป็นอุณหภูมิแรกรับที่รับผู้ป่วยเข้ารับการรักษาตัวในหอผู้ป่วยเด็ก แบ่งเป็นกลุ่มทดลอง และกลุ่มควบคุม กลุ่มละ 24 คน กลุ่มทดลองได้รับโปรแกรมการมีส่วนร่วมในการดูแลเด็กที่มีไข้สูงตามแนวคิดการมีส่วนร่วมของผู้ดูแลร่วมกับการทบทวนวรรณกรรม กลุ่มควบคุมได้รับการพยาบาลตามปกติ เครื่องมือที่ใช้ในการวิจัย ได้แก่ แบบสอบถามข้อมูลทั่วไปของผู้ดูแลและของเด็กที่มีไข้สูง แบบสอบถามความพึงพอใจของผู้ดูแลต่อการพยาบาลเด็กที่มีไข้สูง โดยผ่านการตรวจสอบความตรงเชิงเนื้อหาจากผู้ทรงคุณวุฒิ 3 คน มีค่าดัชนีความตรงตามเนื้อหาเท่ากับ 1 วิเคราะห์ข้อมูลโดยใช้สถิติเชิงพรรณนา และสถิติทดสอบที

ผลการวิจัย : ค่าเฉลี่ยความพึงพอใจของผู้ดูแลระหว่างกลุ่มที่ได้รับโปรแกรมการมีส่วนร่วมในการดูแลเด็กที่มีไข้สูง สูงกว่ากลุ่มที่ได้รับการพยาบาลตามปกติอย่างมีนัยสำคัญทางสถิติที่ระดับ 0.05 (t = 5.182)

สรุป : โปรแกรมการมีส่วนร่วมในการดูแลเด็กที่มีไข้สูง ส่งผลให้ผู้ดูแลเด็กที่มีไข้สูงเกิดความพึงพอใจสูงขึ้น ผู้บริหารการพยาบาล ควรนำโปรแกรมการมีส่วนร่วมในการดูแลเด็กที่มีไข้สูงนี้ไปอบรมพยาบาลเด็ก เพื่อนำไปสอนญาติหรือผู้ดูแลเด็กที่มีไข้สูงได้อย่างมีประสิทธิภาพ


ผลของโปรแกรมส่งเสริมการจัดการตนเองโดยการให้ข้อมูลอย่างมีแบบแผนต่อความสะอาดของลำไส้ใหญ่และความพึงพอใจการบริการพยาบาลของผู้ที่เตรียมตัวก่อนส่องกล้องลำไส้ใหญ่ครั้งแรก, วัชรพันธ์ สุขอุบล, รุ่งรัตติกาล รุ่งเรือง, กัญญดา ประจุศิลป, ศกุนตลา อนุเรือง Jan 2026

ผลของโปรแกรมส่งเสริมการจัดการตนเองโดยการให้ข้อมูลอย่างมีแบบแผนต่อความสะอาดของลำไส้ใหญ่และความพึงพอใจการบริการพยาบาลของผู้ที่เตรียมตัวก่อนส่องกล้องลำไส้ใหญ่ครั้งแรก, วัชรพันธ์ สุขอุบล, รุ่งรัตติกาล รุ่งเรือง, กัญญดา ประจุศิลป, ศกุนตลา อนุเรือง

Journal of Nursing Research, Innovation, and Health

วัตถุประสงค์: เพื่อเปรียบเทียบความสะอาดของลำไส้ใหญ่ และความพึงพอใจการบริการพยาบาล ผู้ที่เตรียมตัวก่อนส่องกล้องลำไส้ใหญ่ครั้งแรกก่อน-หลังเข้าร่วมโปรแกรมส่งเสริมการจัดการตนเองโดยการให้ข้อมูลอย่างมีแบบแผน

รูปแบบการวิจัย: การวิจัยแบบกึ่งทดลอง (Quasi-experimental research design) แบบ 2 กลุ่ม

วิธีการดำเนินการวิจัย: การวิจัยนี้เก็บข้อมูลในระหว่างวันที่ 1 กุมภาพันธ์ ถึง 30 เมษายน 2567  ในผู้ที่เตรียมตัวก่อนส่องกล้องลำไส้ใหญ่ครั้งแรก ณ หอผู้ป่วยนอก แผนกโรคทางเดินอาหารและตับ โรงพยาบาลเอกชน ที่อายุตั้งแต่ 20 ปีขึ้นไป ทั้งเพศชายและเพศหญิง จำนวน 50 คน แบ่งเป็นกลุ่มทดลองและกลุ่มควบคุม กลุ่มละ 25 คน โดยจับคู่กลุ่มตัวอย่างให้มีคุณสมบัติใกล้เคียงกันด้วย อายุและโรค กลุ่มทดลองได้รับโปรแกรมส่งเสริมการจัดการตนเองโดยการให้ข้อมูลอย่างมีแบบแผน ส่วนกลุ่มควบคุมได้รับการพยาบาลตามปกติ เครื่องมือที่ใช้ในการเก็บรวบรวมข้อมูล 3 ชุด ได้แก่ 1) ข้อมูลทั่วไปส่วนบุคคล 2) แบบประเมินสะอาดของลำไส้ 3) แบบประเมินความพึงพอใจบริการพยาบาลของผู้ป่วยนอก สัมประสิทธิ์แอลฟาของครอนบาคได้ 0.8 วิเคราะห์ข้อมูลด้วยสถิติเชิงพรรณนา และ Mann Whitney U test โดยกำหนดระดับนัยสำคัญทางสถิติที่ .05

ผลการวิจัย: หลังสิ้นสุดโปรแกรม กลุ่มทดลองมีความสะอาดของลำไส้ใหญ่ดีกว่ากลุ่มควบคุมอย่างมีนัยสำคัญทางสถิติที่ระดับ .05 และค่าเฉลี่ยคะแนนความพึงพอใจการบริการพยาบาลดีกว่ากลุ่มควบคุมอย่างมีนัยสำคัญทางสถิติที่ระดับ .05

สรุป: โปรแกรมส่งเสริมการจัดการตนเองโดยการให้ข้อมูลอย่างมีแบบแผน ตามแนวคิดทฤษฎีการจัดการตนเอง Creer (2000) ทำให้ผู้ที่เตรียมตัวก่อนส่องกล้องลำไส้ใหญ่ครั้งแรกมีความรู้ และสามารถในการจัดการตนเองได้  เพื่อความสะอาดของลำไส้ใหญ่และความพึงพอใจการบริการพยาบาลได้


Effectiveness Of Interferential Stimulation And Anorectal Neuromuscular Electrical Stimulation On Secondary Encopresis In Children: A Comparative Randomized Controlled Clinical Trial, Seham M. Abd El-Moghny, Mohamed I. Elsepaee, Abdelaty Alghonimy, Rabab S. Mohamed Jan 2026

Effectiveness Of Interferential Stimulation And Anorectal Neuromuscular Electrical Stimulation On Secondary Encopresis In Children: A Comparative Randomized Controlled Clinical Trial, Seham M. Abd El-Moghny, Mohamed I. Elsepaee, Abdelaty Alghonimy, Rabab S. Mohamed

Journal of Medicine in Scientific Research

Background Encopresis, fecal soiling is often secondary to functional constipation and retention. It is significantly impact a child's psychological health as it can result in feelings of shame, social isolation, and low self-esteem and negatively affect their quality of life and their families. Objective To evaluate and compare the efficacy and safety of interferential stimulation (IF) applied on sigmoid colon and anorectal neuromuscular electrical stimulation (NMES), in combination with behavioral therapy and pelvic floor muscle training (PFMT), in improving continence outcomes in children with secondary encopresis refractory to laxatives. Methods In this comparative randomized controlled clinical trial, 30 children (5–10 …


Prospective Validation And Comparison Of Laboratory Risk Indicator For Necrotizing Fasciitis (Lrinec) And Site Other Than Lower Limb, Immunosuppression, Age, Renal Impairment, And Inflammatory Markers (Siari) Scoring Systems For Necrotizing Fasciitis In Critically Ill Patients., Talal Ibrahim Mostafa Hagag, Shimaa Mohamed Kalama Jan 2026

Prospective Validation And Comparison Of Laboratory Risk Indicator For Necrotizing Fasciitis (Lrinec) And Site Other Than Lower Limb, Immunosuppression, Age, Renal Impairment, And Inflammatory Markers (Siari) Scoring Systems For Necrotizing Fasciitis In Critically Ill Patients., Talal Ibrahim Mostafa Hagag, Shimaa Mohamed Kalama

Journal of Medicine in Scientific Research

Background Necrotizing soft tissue infections (NSTIs) are rapidly progressive infections that are dangerous to life, with high morbidity and mortality. Prompt surgical and medical management is necessary and stands mostly on precise identification as well as risk stratification. In order to enhance diagnostic as well as prognostic accuracy, prognostic scoring systems like the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) as well as the most recent Site, Immunosuppression, Age, Renal impairment, and inflammatory markers (SIARI) score, were introduced. Methods A prospective observational cohort study was carried out during June-August 2024 in Shebin Elkom Teaching Hospital among 60 patients who had …


Albuminuria Screening Among Egyptian Patients With Cardiovascular Diseases, Regardless Of Their Diabetic Condition, Amira Fawzy Soliman, Khaled Shelbaya, Wael Abdelatief Mohamed Elhakeem, Osama Louis, Basheer Hafez, Wael Ali, Tarek M.Abdelaziz Elkholy, Baher Emil Ibrahim, Mahmoud M Abdou, Bassem Zarif Jan 2026

Albuminuria Screening Among Egyptian Patients With Cardiovascular Diseases, Regardless Of Their Diabetic Condition, Amira Fawzy Soliman, Khaled Shelbaya, Wael Abdelatief Mohamed Elhakeem, Osama Louis, Basheer Hafez, Wael Ali, Tarek M.Abdelaziz Elkholy, Baher Emil Ibrahim, Mahmoud M Abdou, Bassem Zarif

Journal of Medicine in Scientific Research

Even in the absence of overt kidney disease, albuminuria is increasingly recognized as a marker of systemic endothelial dysfunction and heightened cardiovascular risk. This prospective cohort study aimed to evaluate whether baseline urinary albumin-tocreatinine ratio (UACR) predicts subsequent incident cardiovascular outcomes among Egyptian adults with cardiovascular disease, regardless of diabetic status.


Thyroid Function Abnormalities Among Reproductive-Aged Women With Menstrual Irregularities In A Tertiary Teaching Hospital, Ahmed Alsayed Kassab, Amira Yones Mohamed Jan 2026

Thyroid Function Abnormalities Among Reproductive-Aged Women With Menstrual Irregularities In A Tertiary Teaching Hospital, Ahmed Alsayed Kassab, Amira Yones Mohamed

Journal of Medicine in Scientific Research

Background and Objective:Menstrual irregularities are a common gynecological complaint, often linked to thyroid dysfunction, which disrupts the hypothalamic–pituitary–ovarian axis. This study sought to assess prevalence of thyroid dysfunction among reproductive-aged women with menstrual irregularities and to evaluate the specific clinical and hormonal correlations between different menstrual patterns and Thyroid Status. Methods:A cross-sectional study was conducted on 120 women presenting with menstrual irregularities. Participants were classified as Euthyroid, Subclinical Hypothyroid, Overt Hypothyroid, or Hyperthyroid. Descriptive statistics summarized baseline data (e.g., mean Age = 29.63 plus or minus 7.97 years). The association between Menstrual Irregularity Type and Thyroid Status was assessed using …


What Is The Association Between Iron Deficiency Anemia And The Frequency Or Severity Of Febrile Seizures In Children Under The Age Of 5?, Rehab Fawzy Abdel Mohsen Soliman, Samar Mahmoud Ahmed, Yasmen Ahmed Said, Shaimaa Mohamed Hassan, Dalia Hassanin Hussin, Dina Gaber Soliman, Zeinab Abdalla Ali, Eman Farouk Osman Jan 2026

What Is The Association Between Iron Deficiency Anemia And The Frequency Or Severity Of Febrile Seizures In Children Under The Age Of 5?, Rehab Fawzy Abdel Mohsen Soliman, Samar Mahmoud Ahmed, Yasmen Ahmed Said, Shaimaa Mohamed Hassan, Dalia Hassanin Hussin, Dina Gaber Soliman, Zeinab Abdalla Ali, Eman Farouk Osman

Journal of Medicine in Scientific Research

Background and Aim Febrile seizures (FS) are a common type of convulsion in young children and are frequently associated with fever in the absence of a central nervous system infection. This study aims to investigate the relationship between iron deficiency and febrile seizures, focusing on their occurrence, severity, and recurrence in children aged 6 months to 5 years. Methodology This study employed a case-control design and was conducted at El Sahel Teaching Hospital in Cairo, Egypt, over 12 months. The study sample consisted of 160 children, 80 of whom had febrile seizures and another 80 who were age- and sex-matched …


A Comparison Of Haemodialysis And Renal Transplantation On Male Sexual Function And Hormonal Abnormalities, Hala Ibrahim Mohamed, Ahmad Mohamad Abbas Elseasi Jan 2026

A Comparison Of Haemodialysis And Renal Transplantation On Male Sexual Function And Hormonal Abnormalities, Hala Ibrahim Mohamed, Ahmad Mohamad Abbas Elseasi

Journal of Medicine in Scientific Research

Background Sexual dysfunction and hormonal imbalance are common in males with end-stage renal disease (ESRD), particularly among those on chronic hemodialysis. Kidney transplantation may restore endocrine homeostasis and improve sexual function. This study aimed to compare the effects of hemodialysis and renal transplantation on male sexual function and related hormonal profiles. Methods This cross-sectional study was conducted on 40 married men (≥18 years) with ESRD at National Institute of Urology and Nephrology from October 2024 to October 2025. Participants were divided into two groups: Group I (hemodialysis) and Group II (renal transplantation). Clinical evaluation, laboratory tests, and hormonal assays (Folliclestimulating …


Transcortical Approach For Central Neurocytoma: Efficacy, Safety, And Functional Outcome, Eslam Abozied Kandil Jan 2026

Transcortical Approach For Central Neurocytoma: Efficacy, Safety, And Functional Outcome, Eslam Abozied Kandil

Journal of Medicine in Scientific Research

Background Central neurocytoma (CN) is a rare intraventricular neuronal tumor that predominantly affects young adults and is frequently associated with obstructive hydrocephalus. Surgical resection remains the cornerstone of treatment, yet the optimal surgical corridor and predictors of long-term outcome remain debated. Objective To evaluate the efficacy, safety, functional outcomes, and oncological control of transcortical microsurgical resection for central neurocytoma at a single neurosurgical center. Methods A retrospective review was conducted of all patients undergoing transcortical resection of central neurocytoma between 2017 and 2025. Clinical presentation, radiological characteristics, surgical approach, extent of resection, cerebrospinal fluid (CSF) diversion, postoperative complications, functional outcomes, …


The Impact And Prevalence Of Pain In Adolescents And Children Living With Type-One Diabetes Mellitus, Randa Mohamed Darwish, Ayat Ibrahim Ghanem, Lamis Safwat Mubarak Jan 2026

The Impact And Prevalence Of Pain In Adolescents And Children Living With Type-One Diabetes Mellitus, Randa Mohamed Darwish, Ayat Ibrahim Ghanem, Lamis Safwat Mubarak

Journal of Medicine in Scientific Research

Background: Pain is frequent but often underrated and even overlooked in adolescents and children living with type-one diabetes mellitus and can negatively impact their quality of life(QoL) and their cooperation within the management plan. Objective: To discern the common types , severity and prevalence of pain in pediatrics living with type-one-diabetes;compared to the group of diabetes-free control, and to probe associations with glycemic control, fatigue, and (QoL). Methods: This cross-sectional study incorporated 102 adolescents and children withtype -one- diabetesmellitus; and 99 age- and sex-matched healthy peers aged 8- 16 years. Pain intensity was evaluated using the (body-pain) domain in the …


Atrial Fibrillation After Off-Pump Versus On-Pump Coronary Artery Bypass Grafting Surgery, Ahmed Abdalla Mohamed, Ahmed M Elshemy, Sherif M Elboghdady, Wael S Nekhila, Azza A Katta Jan 2026

Atrial Fibrillation After Off-Pump Versus On-Pump Coronary Artery Bypass Grafting Surgery, Ahmed Abdalla Mohamed, Ahmed M Elshemy, Sherif M Elboghdady, Wael S Nekhila, Azza A Katta

Journal of Medicine in Scientific Research

Background Among postoperative arrhythmic complications, atrial fibrillation (AF) exhibits the greatest prevalence after coronary artery bypass grafting (CABG). This study investigates the comparative prevalence of AF between on-pump and off-pump techniques. Aim To compare the POAF (post-operative atrial fibrillation) incidence between off-pump and on-pump CABG Methods A randomized (simple) cohort study prospectively investigated the influence of surgical practice in CABG, contrasting off-pump (OPCAB) and on-pump (ONCAB) methods, on the early postoperative occurrence of atrial fibrillation (POAF), defined as within the first 24 hours post-surgery. In a cohort of 128 consecutive patients (95 off-pump, 33 on-pump), the study compared groups based …


Evaluation Of Left Cardiac Chamber And Cardiac Size With Non Ecg Gated Ct In Cancer Patients And Its Role In Determining Cardiomyopathy, Manal Mohamed Refaat Beshir, Samia Yehia Heikal, Shaimaa Abdalaleem Abdalgeleel, Dalia Ibraheem El Saied, Sarah Mamdouh Osman Jan 2026

Evaluation Of Left Cardiac Chamber And Cardiac Size With Non Ecg Gated Ct In Cancer Patients And Its Role In Determining Cardiomyopathy, Manal Mohamed Refaat Beshir, Samia Yehia Heikal, Shaimaa Abdalaleem Abdalgeleel, Dalia Ibraheem El Saied, Sarah Mamdouh Osman

Journal of Medicine in Scientific Research

Background: A number of cardiovascular processes have been linked to cardiac chamber and cardiac size increase as a significant biomarker for predicting morbidity and death. There is no standardized technique for assessing and reporting cardiac chamber and cardiac size, despite the fact that non-electrocardiographically (ECG) gated multidetector CT is a frequently utilized cross-sectional imaging modality to assess numerous cardiothoracic diseases . Patients and Methods :Our study encompassed 106 patients. All patients were diagnosed with primary cancer and underwent computed tomography (CT) for either initial evaluation or subsequent monitoring. Cardiac measurements were obtained in CT and compared to Echocardiographic results done …


Association Of Arterial Partial Oxygen Pressure With Mortality In Critically Ill Patients With Sepsis: An Observational Prospective Cohort Study, Talal Ibrahim Mostafa Hagag, Salwa M.A. Dahesh Jan 2026

Association Of Arterial Partial Oxygen Pressure With Mortality In Critically Ill Patients With Sepsis: An Observational Prospective Cohort Study, Talal Ibrahim Mostafa Hagag, Salwa M.A. Dahesh

Journal of Medicine in Scientific Research

Background Up till now, the best oxygenation plan in sepsis is a moot point. Although both hypoxemia and hyperoxemia have been linked to negative outcomes, it is unclear whether the arterial oxygen tension (PaO₂) contributes to mortality on its own. The present study aimed to study the association between the arterial partial oxygen pressure and the mortality among critically ill patients with sepsis. Methods A prospective observational study was carried out, including 120 critically ill patients with sepsis. The patients were classified according to arterial partial oxygen pressure into two groups: the PaO₂ >80 mmHg group, which included 61 patients, …


Applicability Of The Cleveland Clinic Scoring Tool For The Risk Prediction Of Acute Kidney Injury After Adult Cardiac Surgery., Ahmed A Faragalla, Ahmed M Elshiemy, Wael S Nekhila, Sherif M Elboghdady Jan 2026

Applicability Of The Cleveland Clinic Scoring Tool For The Risk Prediction Of Acute Kidney Injury After Adult Cardiac Surgery., Ahmed A Faragalla, Ahmed M Elshiemy, Wael S Nekhila, Sherif M Elboghdady

Journal of Medicine in Scientific Research

Background Post-cardiac surgery acute kidney injury (AKI) is a significant complication associated with increased mortality, longer ICU stays, and higher healthcare costs. The Cleveland Clinic Scoring Tool (CCST) aids preoperative risk evaluation, facilitating tailored prevention strategies. Aim This study evaluates the relevance of the CCST in prospectively assessing AKI risk in adult patients undergoing various cardiac surgeries. Methods This prospective cohort study (tertiary centre, Jan 2021-Aug 2023) assessed the CCST for preoperative AKI risk in adult open-heart surgery (OHS) patients. Consenting adults (≥18) undergoing elective/emergency OHS were included, excluding those with pre- AKI (KDIGO), dialysis-dependent ESRD, aortic dissection, shock, or …


The Postoperative Analgesic Effect Of Lumbar Erector Spinae Plane Block Versus Pericapsular Nerve Group Block In Patients Undergoing Hip Surgeries, Islam M. El-Desoky, Mohamed Elshafey, Amal Ismail Abdelrahman Jan 2026

The Postoperative Analgesic Effect Of Lumbar Erector Spinae Plane Block Versus Pericapsular Nerve Group Block In Patients Undergoing Hip Surgeries, Islam M. El-Desoky, Mohamed Elshafey, Amal Ismail Abdelrahman

Journal of Medicine in Scientific Research

Background: Hip surgery requires effective pain control for proper recovery and decreasing the length of hospital stay. Aims: We aimed to assess the analgesic effect of Erector spinae plane block (ESPB) and pericapsular nerve group (PENG) blocks in pain control after hip operations. Methods: This randomized clinical trial included 69 ASA I–II patients scheduled for hip surgery were randomly allocated into three groups: PENG block, ESPB, and control groups (23 each). The primary outcome was postoperative pain assessed via the Numeric Rating Scale (NRS) at rest and during movement. Secondary outcomes included intraoperative and 48-hour morphine consumption, time to first …


The Role Of Human Sarcosine Dehydrogenase And Endothelial Growth Factor In Early Diagnosis Of Cancer Prostate, Hala Ibrahim Mohamed, Amr Mohamed Mounier Elsofy Jan 2026

The Role Of Human Sarcosine Dehydrogenase And Endothelial Growth Factor In Early Diagnosis Of Cancer Prostate, Hala Ibrahim Mohamed, Amr Mohamed Mounier Elsofy

Journal of Medicine in Scientific Research

Background: As the second most common cancer in males, prostate cancer contributes significantly to cancer-related deaths. Prostate-specific antigen (PSA) test and digital rectal examinations are used to identify it, albeit PSA screenings frequently produce unreliable results. Initial symptoms may include sexual dysfunction and urinary problems. The standard diagnostic method is biopsies, which are carried out under the direction of ultrasound or magnetic resonance imaging (MRI). However, they are risky and can result in infections and erectile dysfunction, which emphasizes the need for better biomarkers. Sarcosine and vascular endothelial growth factor are important metabolites associated with the progression of prostate cancer, …


Role Of New-Onset Qt Prolongation In Ecg In Critically Ill Septic Patients As A Prognostic Tool: An Observational Prospective Cohort Icu Study, Talal Ibrahim Mostafa Hagag, Salwa M.A. Dahesh Jan 2026

Role Of New-Onset Qt Prolongation In Ecg In Critically Ill Septic Patients As A Prognostic Tool: An Observational Prospective Cohort Icu Study, Talal Ibrahim Mostafa Hagag, Salwa M.A. Dahesh

Journal of Medicine in Scientific Research

Background QT interval prolongation is a common finding among critically ill patients and could be a marker of autonomic nervous dysregulation, instability of metabolism, and/or septic cardiomyopathy. Nevertheless, its prognostic role among septic ICU populations remains unclarified. The current aim of this study was to explore its potential role regarding short-term mortality. Methods In this cohort study, 119 septic adults were included in the study within 24 hours of ICU admission. Demographics, clinical variables, lab values, and QTc intervals were measured within 2 hours of ICU admission following exclusion for clinically significant electrolyte imbalances and use of QT-prolonging medications. QTc …


Physical Activity Buffers Screen Time's Impact On Flourishing In Us Youth And Children: Findings From The 2022-2023 Nsch, Aliya Kuerban Phd, Fnp-Bc, Ms, Ma, Rn, Ling Shi Jan 2026

Physical Activity Buffers Screen Time's Impact On Flourishing In Us Youth And Children: Findings From The 2022-2023 Nsch, Aliya Kuerban Phd, Fnp-Bc, Ms, Ma, Rn, Ling Shi

Nursing: Faculty Publications

Objective

This study aimed to examine the independent and combined effects of screen time and physical activity on flourishing among US children and adolescents in the postpandemic era.

Methods

This cross-sectional study used existing data from the 2022 to 2023 National Survey of Children’s Health, a nationally representative survey of US children. A total of 47,673 children and adolescents aged 6 to 17 years were included. Multivariate logistic regression models were applied to examine the main effects and interactions between screen time and physical activity on flourishing, adjusting for sociodemographic covariates.

Results

Lower screen time and higher physical activity were …


We-Making Through Technology: Social Cohesion And Virtual Adaptation In Community Arts Organizations For Artists With Idd During Covid-19 Pandemic, Yumi Shirai, Michelle Boulanger Thompson, Tamara Shetron Jan 2026

We-Making Through Technology: Social Cohesion And Virtual Adaptation In Community Arts Organizations For Artists With Idd During Covid-19 Pandemic, Yumi Shirai, Michelle Boulanger Thompson, Tamara Shetron

Rehabilitation Sciences Faculty Publications

COVID-19 public health restrictions disrupted in-person arts participation, increasing risks of social isolation and reduced community access. Prior research shows that many people engaged in home-based arts and cultural activities during lockdown, supporting emotional regulation, a sense of belonging, and social connection; however, little is known about how these shifts affected community arts organizations that serve artists with intellectual and/or developmental disabilities (IDD), a population disproportionately impacted by the pandemic and longstanding inequities. We examined how community-based arts organizations adapted programming for artists with IDD during the COVID-19 pandemic, including barriers and unanticipated outcomes relevant to equitable access and participation …


First Steps: Supporting Infant Development And Family Bonding, Katana M. Evans Jan 2026

First Steps: Supporting Infant Development And Family Bonding, Katana M. Evans

Entry Level Occupational Therapy Doctoral Capstone Projects Class of 2026

First Steps: Supporting Infant Development and Family Bonding is a capstone project that was developed to bring awareness to the importance of development within the first few months of life, as well as exploring occupational therapy’s role with this population. The project focused on areas of program development, education, and clinical skill development, which were all developed following the completion of a scoping review. Educational materials, including a video library, were created for families to continue to access materials following the completion of the experience. These videos covered topics including safe sleep, milestones, tummy time, and more. Additionally, two sessions …


Rheumatic Resilience: An Occupational Therapy Approach, Shannon N. O'Donnell Jan 2026

Rheumatic Resilience: An Occupational Therapy Approach, Shannon N. O'Donnell

Entry Level Occupational Therapy Doctoral Capstone Projects Class of 2026

Rheumatic conditions affect nearly one in four adults in the United States (U.S. Department of Health and Human Services, n.d.) and are characterized by chronic, often progressive symptoms, requiring long-term self-management. Despite this need, accessible and non-pharmacological resources remain limited. The capstone project, Rheumatic Resilience: An Occupational Therapy Approach, was developed to address this gap by promoting sustainable symptom management strategies through programming and education, while increasing awareness of occupational therapy (OT)’s role in chronic pain management. This project focused on areas of program development, education, clinical practice, and advocacy. A 10-week, in-person program based on Lifestyle Redesign principles was …


Holistic Healing Through Horses: An Evaluation Of Interdisciplinary Collaboration In Equine-Assisted Services And Associated Pilot Program, Catherine M. Balestrini, Kathleen Hughes-Butcher Jan 2026

Holistic Healing Through Horses: An Evaluation Of Interdisciplinary Collaboration In Equine-Assisted Services And Associated Pilot Program, Catherine M. Balestrini, Kathleen Hughes-Butcher

Entry Level Occupational Therapy Doctoral Capstone Projects Class of 2026

Holistic Healing through Horses: An Evaluation of Interdisciplinary Collaboration in Equine-Assisted Services and Associated Pilot Program was an occupational therapy doctoral capstone project conducted through Misericordia University. This project involved the implementation of equine-assisted services to improve occupational capabilities of physically disabled community-dwelling adults and research related to interdisciplinary collaboration in the equine-assisted service industry. The education component of this capstone disseminated information regarding safe techniques and procedures for volunteers involved in the Holistic Healing through Horses program. The program component of Holistic Healing through Horses involved 12 weekly sessions designed to target goal areas of the respective participants. Progress …