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Articles 8011 - 8040 of 329124
Full-Text Articles in Medicine and Health Sciences
Impact Of Provider Self-Efficacy On Caring For Patients With Prediabetes, David R. Knight
Impact Of Provider Self-Efficacy On Caring For Patients With Prediabetes, David R. Knight
Doctor of Nursing Practice Projects
Prediabetes affects millions of adults in the United States, yet inconsistent provider knowledge and confidence limit evidence-based screening and management in primary care, a gap well-documented in the literature. The purpose of this quality improvement project was to evaluate whether a structured educational intervention improved provider self-efficacy related to prediabetes identification and management. Guided by Social Cognitive Theory and the Transtheoretical Model, with implementation guided by the Plan-Do-Study-Act cycle, this project asked: among family practice providers, how does prediabetes education affect provider self-efficacy over four weeks? A quasi-experimental pre/post design was used. Four asynchronous educational modules focused on evidence-based screening, …
Quality Improvement Project: The Critical Role Of Provider Knowledge In The Golden Hour, Kimberly Mcglothan
Quality Improvement Project: The Critical Role Of Provider Knowledge In The Golden Hour, Kimberly Mcglothan
Doctor of Nursing Practice Projects
Maternal and infant mortality rates in the Southern United States remain disproportionately high, and inconsistent implementation of the Golden Hour, defined as uninterrupted skin to skin contact for at least the first hour after birth, continues to limit its evidence based maternal and neonatal benefits. The aim of this Doctor of Nursing Practice (DNP) quality improvement project was to evaluate the impact of a structured provider education intervention on Golden Hour compliance and provider confidence. Guided by Benner’s Novice to Expert Theory and implemented using Kotter’s 8-Step Change Model, a quantitative, quasi experimental pre-post design was used. The project was …
Quality Improvement Project: Faculty Preparedness For Recognition, De Escalation, And Reporting Of Violence In Clinical Education Settings, Dawn "Deedee" D. Moline
Quality Improvement Project: Faculty Preparedness For Recognition, De Escalation, And Reporting Of Violence In Clinical Education Settings, Dawn "Deedee" D. Moline
Doctor of Nursing Practice Projects
Violence and aggression in healthcare settings present ongoing safety concerns for nursing faculty supervising students during clinical education, particularly when teaching occurs in hospital environments where faculty are not employed. Faculty often rotate across multiple clinical sites and may lack consistent preparation or access to standardized safety education and reporting systems. The purpose of this Doctor of Nursing Practice quality improvement project was to evaluate the effect of a targeted educational intervention on nursing faculty perceived preparedness to recognize, de escalate, and report aggression encountered during clinical instruction. Guided by Bandura’s Social Cognitive Theory and Lewin’s Three Stage Change Model, …
Implementing Simulation-Based Learning In Fieldwork Bootcamp To Enhance Level Ii Fieldwork Preparedness, Kathryn Livingston
Implementing Simulation-Based Learning In Fieldwork Bootcamp To Enhance Level Ii Fieldwork Preparedness, Kathryn Livingston
OTD Capstone Projects
This doctoral capstone project was completed in collaboration with Belmont University’s School of Occupational Therapy (OT) and the Center for Interprofessional Engagement & Simulation. A needs assessment of OT Faculty, Level II Fieldwork Educators, and the OTD Class of 2026 identified essential skill expectations and common areas of difficulty related to Level II placements. In response, this project developed multiple simulation experiences for Fieldwork Bootcamp to provide students with hands-on practice of core skills in preparation for their Level II placements. A resource manual was developed containing case studies, training guides, debriefing scripts, and setting-specific materials for use during Fieldwork …
Promoting Participation In Leisure Activities At The Center For Living And Learning, Katie Eison
Promoting Participation In Leisure Activities At The Center For Living And Learning, Katie Eison
OTD Capstone Projects
The Center for Living and Learning is a private nonprofit residential treatment facility on a 30-acre farm in Franklin, TN, housing adults who experience severe and persistent mental illnesses such as schizophrenia and schizoaffective disorder. The Center provides opportunities for leisure activities during the day; however, due to symptomology such as avolition, anhedonia, and social withdrawal, residents often struggle with participation in valued leisure activities. This doctoral capstone project aimed to promote participation in leisure activities, social participation, and community engagement. The Interest Checklist and Leisure Satisfaction Measure were administered to determine residents’ individual interests and satisfaction levels with leisure …
Quality Improvement Project: The Impact Of The Clinical Judgment Measurement Model In Nursing Faculty, Lamia Zeidan
Quality Improvement Project: The Impact Of The Clinical Judgment Measurement Model In Nursing Faculty, Lamia Zeidan
Doctor of Nursing Practice Projects
Clinical judgment is essential for nursing practice and can be taught using the Clinical Judgment Measurement Model (CJMM). A needs assessment conducted at the project site revealed that students had limited clinical judgment skills, there was no emphasis on clinical judgment in nursing skills courses, and the faculty had a limited understanding of the CJMM. In response to the findings of the needs assessment, the quality improvement (QI) project was developed using a quasi-experimental design. Guided by Lewin’s Change Theory and Benner’s Novice to Expert Educator theoretical framework, the project aimed to provide faculty with education on the CJMM and …
Optimizing Central Line Discontinuation In The Surgical Intensive Care Unit: A Quality Improvement Initiative Using A Visual Aid To Reduce The Risk Of Central Line-Associated Bloodstream Infections, John Quyen D. Van
Doctor of Nursing Practice Final Project Abstract
PURPOSE
The aim of this quality improvement (QI) project was to reduce unnecessary central line dwell time by 20% in a surgical intensive care unit (SICU) in Central Texas.
BACKGROUND
Central line–associated bloodstream infections (CLABSIs) contribute to patient harm and increased healthcare costs. The literature strongly supports the timely removal of central venous catheters (CVCs) to reduce this risk; however, delays often occur due to workflow demands, communication gaps, and inconsistent daily necessity assessments.
METHODOLOGY
Guided by the Health Belief Model (HBM) and the Institute for Healthcare Improvement (IHI) Model for Improvement, the QI project consisted of an 8-week baseline …
Quality Improvement Project: Improving The Clinical Teaching Experience Through Clinical Adjunct Orientation, Elissa Saunders
Quality Improvement Project: Improving The Clinical Teaching Experience Through Clinical Adjunct Orientation, Elissa Saunders
Doctor of Nursing Practice Projects
Clinical adjunct nursing faculty often transition into academic roles without formal preparation, leading to role insecurity and high turnover rates that negatively impact student clinical experiences. The purpose of this quality improvement (QI) project was to implement a structured orientation checklist to improve perceived clinical teaching competency among novice clinical adjunct faculty. The project aimed to standardize onboarding and support the transition from clinical practice to academia. A quantitative pre-post intervention design was used with a convenience sample of clinical adjunct faculty employed for less than one year at a rural university nursing program. The project was guided by Kotter’s …
Strengthening Evaluation For Student Success, Hollan Scrivner
Strengthening Evaluation For Student Success, Hollan Scrivner
Doctor of Nursing Practice Projects
Student evaluation is an important factor in guiding students to develop self-confidence and gain competency in nursing skills. For evaluation to be effective, it must be consistent. The purpose of this quality improvement project is to implement a training program to improve consistency and interrater reliability among faculty conducting skill evaluations. The impact of the training program will be measured by a pre- and post-grading exercise using a skills rubric. Data will be extracted from the rubrics and entered into a codebook for data analysis. The project was guided by the theoretical framework of Stephens’ Star Model of Knowledge Transformation …
Enhancing Provider Self-Efficacy And Documentation In Hypertension Management, Stephanie Nsiah
Enhancing Provider Self-Efficacy And Documentation In Hypertension Management, Stephanie Nsiah
Doctor of Nursing Practice Projects
Primary care providers often experience inconsistent confidence and incomplete documentation when managing hypertension, contributing to suboptimal blood pressure control. This quality improvement project addressed the need for structured provider education at an outpatient family clinic. The purpose was to evaluate the impact of a structured educational intervention on provider self-efficacy and documentation completeness. Using a quasi-experimental pre-post design guided by the Plan-Do-Study-Act model and Lewin's Change Theory, a 60-minute educational session was delivered to 12 licensed providers. Participants completed pre- and post-intervention self-efficacy surveys using the Acceptability of Intervention Measure (AIM) and Intervention Appropriateness Measure (IAM) and Feasibility of Intervention …
Vasculature Of The Anterior Abdominal Wall And Surface Anatomy Of The Liver And Stomach: Considerations For Minimal Access Surgeries In Neonates, Daniël J. Van Tonder, Natalie Keough, Martin Louis Van Niekerk, Albert Van Schoor
Vasculature Of The Anterior Abdominal Wall And Surface Anatomy Of The Liver And Stomach: Considerations For Minimal Access Surgeries In Neonates, Daniël J. Van Tonder, Natalie Keough, Martin Louis Van Niekerk, Albert Van Schoor
COM Scholarship
Background: Minimal access surgeries are growing more common in neonatal care, but the risk of accidental injury to abdominal wall blood vessels remains a concern. This risk is increased by limited precise anatomical data specific to neonates. Therefore, this study aimed to quantitatively map the superficial and deep blood vessels of the neonatal anterior abdominal wall concerning important surgical landmarks to develop evidence-based recommendations for safer laparoscopic port placement. Methods: Thirty formalin-fixed low-birth-weight neonatal body donations (≤4 weeks old) were dissected. An anatomical grid based on palpable landmarks—including the umbilicus, xiphoid process, and anterior superior iliac spines—was utilised to measure …
Equine-Assisted Interventions For Pediatric Clients With Cerebral Palsy: A Handbook For Occupational Therapists, Draydin Ferguson, Lesley Khan-Farooqi, Phd, Otd, Otr
Equine-Assisted Interventions For Pediatric Clients With Cerebral Palsy: A Handbook For Occupational Therapists, Draydin Ferguson, Lesley Khan-Farooqi, Phd, Otd, Otr
Spring 2026 OTD Capstone Symposium
This poster outlines the development of an evidence-informed instructional handbook intended to guide Occupational Therapists in implementing equine-assisted interventions with pediatric clients diagnosed with Cerebral Palsy.
Groove ‘N’ Grow: Promoting Social Participation Through Dance And Movement, Juliana N. Ward, Karen Park
Groove ‘N’ Grow: Promoting Social Participation Through Dance And Movement, Juliana N. Ward, Karen Park
Spring 2026 OTD Capstone Symposium
Groove ‘n’ Grow is a structured pediatric occupational therapy group program designed to improve social participation, engagement, and sensory regulation in children with developmental and sensory processing differences through dance and movement-based activities. The program was developed as part of an occupational therapy doctoral capstone project and implemented within a pediatric outpatient therapy clinic. The purpose of the program is to provide children with developmental and sensory processing differences opportunities to practice peer engagement, cooperative participation, emotional regulation, and emotional awareness in a supportive small-group environment.
Barriers Of Animal Assisted Therapy, Taylor Blanchard, Amy Lyons-Brown
Barriers Of Animal Assisted Therapy, Taylor Blanchard, Amy Lyons-Brown
Spring 2026 OTD Capstone Symposium
This study employs a mixed-methods design, integrating online surveys, semi-structured interviews, and clinical observations to examine the use of animal-assisted therapy (AAT) within occupational therapy practice. The primary objectives are to characterize the demographics of occupational therapists and therapy animals engaged in AAT, identify barriers to its implementation, and evaluate the resources currently available to support practitioner knowledge and competency. By addressing these areas, the study seeks to clarify existing gaps in education and practice, with the broader goal of strengthening the evidence base and enhancing the accessibility, consistency, and impact of AAT in occupational therapy.
Albumin Use In Cardiopulmonary Bypass Pump Prime And Its Association With Postoperative Renal Function And Acute Kidney Injury: A Scoping Review, Hannah Talbot
Student Works
ABSTRACT
1.Structured summary:
Background: Cardiopulmonary bypass (CPB) is associated with significant hemodilution, inflammatory activation, and alterations in renal perfusion, all of which may contribute to postoperative acute kidney injury (AKI). Albumin is frequently used as a component of CPB pump prime due to its oncotic properties and potential to mitigate fluid shifts and support intravascular volume. However, the extent to which albumin-containing priming solutions influence postoperative renal outcomes remains unclear.
Objective: This scoping review aimed to map the available literature examining the use of albumin in CPB pump prime and its reported effects on renal function and the incidence …
Antibacterial Tellurium Dioxide Nanoparticles Incorporated Into An Adhesive Wound Dressing, Tina Hesabizadeh, Rajendra Subedi, Rolando Baez, Thomas J. Webster, Gregory Guisbiers
Antibacterial Tellurium Dioxide Nanoparticles Incorporated Into An Adhesive Wound Dressing, Tina Hesabizadeh, Rajendra Subedi, Rolando Baez, Thomas J. Webster, Gregory Guisbiers
Faculty Scholarship
Tellurium dioxide (TeO2) nanoparticles were synthesized by pulsed laser ablation in liquids (PLAL) using a bottom-ablation configuration, with deionized water as the solvent and pure tellurium pellets as the target. The resulting nanoparticles were spherical, with an average diameter of 56 ± 13 nm. Phase analysis indicated that the nanoparticles consisted mainly of around 83% of paratellurite α-TeO2, with a minor fraction, i.e., around 17% of the metastable γ-TeO2 phase. The antibacterial performance of the TeO2 nanoparticles was evaluated against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis, and methicillin-resistant Staphylococcus aureus (MRSA), demonstrating broad-spectrum antibacterial activity at concentrations as low as …
Knowledge, Skills, And Attitudinal Gaps In Fibrodysplasia Ossificans Progressiva Diagnosis And Management In The United States, Patrice Lazure, Matthew Drake, Michelle Davis, Corrie Crowe, Zvi Grunwald, Lu Fan, Suzanne Murray
Knowledge, Skills, And Attitudinal Gaps In Fibrodysplasia Ossificans Progressiva Diagnosis And Management In The United States, Patrice Lazure, Matthew Drake, Michelle Davis, Corrie Crowe, Zvi Grunwald, Lu Fan, Suzanne Murray
Department of Anesthesiology Faculty Papers
Fibrodysplasia ossificans progressiva (FOP) is an ultra-rare and disabling disease. Preventing unnecessary and/or harmful medical procedures to patients requires early and accurate diagnosis, multidisciplinary care, and access to specialists with FOP expertise. This study aims to assess the needs of healthcare providers (HCPs) when providing care to patients with FOP. Knowledge, confidence, and management practices were measured through a short awareness survey, completed by 400 HCPs from different specialties who may encounter patients with FOP. Complementary qualitative data were obtained from a dialogue session about FOP. Quantitative data was analyzed using descriptive and inferential analysis, while qualitative data underwent thematic …
Lotilaner Ophthalmic Solution 0.25% In The Treatment Of Demodex Blepharitis: A Case Report, Marjan Farid, Ian Benjamin Gaddie, Preeya K Gupta, Cecelia Koetting, Richard Lindstrom, Selina Mcgee, Kelly K Nichols, Laura M Periman, Stephen Pflugfelder, Christopher Starr, Nandini Venkateswaran, Elizabeth Yeu
Lotilaner Ophthalmic Solution 0.25% In The Treatment Of Demodex Blepharitis: A Case Report, Marjan Farid, Ian Benjamin Gaddie, Preeya K Gupta, Cecelia Koetting, Richard Lindstrom, Selina Mcgee, Kelly K Nichols, Laura M Periman, Stephen Pflugfelder, Christopher Starr, Nandini Venkateswaran, Elizabeth Yeu
Faculty, Staff and Students Publications
Demodex blepharitis is a chronic inflammatory ocular condition caused by Demodex mite infestation of the eyelid that can negatively impact quality of life. Currently, lotilaner ophthalmic solution 0.25% is the only FDA-approved treatment for Demodex blepharitis. The Demodex Expert Panel on Treatment and Eyelid Health has established consensus that lotilaner ophthalmic solution 0.25% should be considered the preferred first-line treatment for Demodex blepharitis. We report a patient who presented with collarettes, the pathognomonic sign of Demodex blepharitis, meibomian gland dysfunction, and poor visual acuity. The patient also had a history of neovascular age-related macular degeneration. Consistent with the Demodex Expert …
Dna Deformability In Sequence-Dependent Capture Of E. Coli Gyrase, Jonathan M Fogg, Silvia L Summers, Marlène Vayssières, Nils Marechal, Valérie Lamour, Wilma K Olson, Lynn Zechiedrich
Dna Deformability In Sequence-Dependent Capture Of E. Coli Gyrase, Jonathan M Fogg, Silvia L Summers, Marlène Vayssières, Nils Marechal, Valérie Lamour, Wilma K Olson, Lynn Zechiedrich
Faculty, Staff and Students Publications
To understand how gyrase interacts with DNA and selects a site of action, we created an ad hoc shape-based recognition methodology to ascertain the DNA sequence from cryoEM density maps as a string of purines and pyrimidines, which matched to the DNA minicircle sequence in our two previous cryoEM structures of negatively supercoiled DNA bound to E. coli gyrase. For one structure, the Gate- or G-segment sequence contains base-pair steps that are among the most flexible in the minicircle, facilitating the bend. The sequence flanking this G-segment is highly inflexible, preventing wrapping the β-pinwheel of gyrase. In the other structure, …
First, Do No Trend: Aligning Parenteral Lipid Therapy With Physiology And Evidence In Neonates, Muralidhar H Premkumar
First, Do No Trend: Aligning Parenteral Lipid Therapy With Physiology And Evidence In Neonates, Muralidhar H Premkumar
Faculty, Staff and Students Publications
Lipid injectable emulsions (ILE) are essential components of parenteral nutrition in neonatal intensive care units. Over the past two decades, the expanded availability of ILE has led to rapid changes in clinical practice, largely driven by concerns about intestinal failure–associated liver disease. Despite these evolving trends, the evidence supporting one ILE over another remains limited and nuanced. Importantly, no currently available ILE replicates the intrauterine supply of critical long-chain polyunsaturated fatty acids, particularly arachidonic acid and docosahexaenoic acid, both of which decline postnatally regardless of emulsion type. Neonates requiring ILE represent a heterogeneous population of preterm and term infants, with …
From Browsing To Building: Navigating Your Google Resource Space (Drive & Site), Libby Cunningham
From Browsing To Building: Navigating Your Google Resource Space (Drive & Site), Libby Cunningham
Capstone Projects
This capstone project aimed to develop a trauma-informed, evidence-based support hub for Court Appointed Special Advocates (CASA) working with children involved in the foster care system. CASA advocates are frequently exposed to secondary trauma, burnout, and compassion fatigue, which can impact their effectiveness and overall well-being. Additionally, trauma exposure significantly affects children’s emotional regulation, behavior, and participation in daily occupations. The primary objective of this project was to design, develop, and organize a comprehensive digital resource platform tailored to the needs of Kalamazoo CASA and their active cases. Utilizing evidence-based literature on trauma-informed care and secondary trauma, relevant resources were …
The Missing Link Between Occupational Therapy And Hemodialysis: Program Development And Implementing Intradialytic Ot In A Rural Hospital Setting, Madison Maki
Capstone Projects
Occupational therapy (OT) has demonstrated effectiveness in supporting individuals undergoing hemodialysis, a life‑altering yet lifesaving treatment for end‑stage renal disease (ESRD) and chronic kidney disease (CKD). Despite this, hospitalized patients who require dialysis often receive reduced rehabilitation services due to the time‑intensive nature of dialysis and the productivity demands placed on therapists. Additionally, gaps in therapist knowledge regarding the unique functional deficits and educational needs of this population further limit service delivery.
This doctoral capstone project (DCE), conducted at Upper Peninsula Health System (UPHS), a hospital in rural Northern Michigan, addressed these barriers through the development of a comprehensive resource …
Development Of 6-Week Tier 2 Intervention Tracks Within An Elementary Mtss Framework, Maxwell Lyle
Development Of 6-Week Tier 2 Intervention Tracks Within An Elementary Mtss Framework, Maxwell Lyle
Capstone Projects
The Multi-Tiered System of Supports (MTSS) is designed to provide levels of support with differing intensity that align with student needs. Tier 1 is universal instruction provided to all students in the classroom. Students who do not demonstrate adequate progress may receive Tier 2 interventions, which are primarily small-group and, when appropriate, individual interventions that are skill-specific, time-bound (6–8 weeks), and include progress monitoring. Students who do not respond to Tier 2 may require Tier 3 supports, which are intensive, individualized interventions. Many school systems lack consistent, structured Tier 2 supports, particularly in Occupational Therapy-related skills, such as fine motor …
Eating Vs. Competing: Comparing Pressures Of Disordered Eating In Lean And Non-Lean Sports, Brielle G. Newland, Meredith Meyer
Eating Vs. Competing: Comparing Pressures Of Disordered Eating In Lean And Non-Lean Sports, Brielle G. Newland, Meredith Meyer
Undergraduate Honors Thesis Projects
In the current study, I compared the risk factors of disordered eating between athletes in weight dependent and non-weight dependent sports, specifically the motivating pressures to pursue this behavior. Weight dependent or “lean athletes” participate in sports with emphasis on weight, size, or bodily appearance. Non-weight dependent or “non-lean athletes” participate in sports without emphasis on weight or aesthetics, which tend to be team sports. While there are many different disordered eating risk factors in athletics, the current study focused on sport based pressures and societal based pressures. Participants included undergraduate student athletes on female athletic teams or dance minors …
Genome-Wide Association Study Of Copy Number Variations In Parkinson’S Disease, Zied Landoulsi, Ashwin Ashok Kumar Sreelatha, Nicole Kuznetsov, Claudia Schulte, Dheeraj Reddy Bobbili, Ludovica Montanucci, Costin Leu, Lisa-Marie Niestroj, Emadeldin Hassanin, Cloé Domenighetti, Pierre-Emmanuel Sugier, Milena Radivojkov-Blagojevic, Peter Lichtner, Berta Portugal, Connor Edsall, Jens Krüger, Dena G Hernandez, Cornelis Blauwendraat, George D Mellick, Alexander Zimprich, Walter Pirker, Manuela Tan, Ekaterina Rogaeva, Anthony Lang, Sulev Koks, Pille Taba, Suzanne Lesage, Alexis Brice, Jean-Christophe Corvol, Marie-Christine Chartier-Harlin, Eugenie Mutez, Kathrin Brockmann, Angela B Deutschländer, Georges M Hadjigeorgiou, Efthimos Dardiotis, Leonidas Stefanis, Athina Maria Simitsi, Enza Maria Valente, Simona Petrucci, Letizia Straniero, Anna Zecchinelli, Gianni Pezzoli, Laura Brighina, Carlo Ferrarese, Grazia Annesi, Andrea Quattrone, Monica Gagliardi, Lena F Burbulla, Hirotaka Matsuo, Akiyoshi Nakayama, Nobutaka Hattori, Kenya Nishioka, Sun Ju Chung, Yun Joong Kim, Lukas Pavelka, Pierre Kolber, Bart Pc Van De Warrenburg, Bastiaan R Bloem, Andrew B Singleton, Dan Vitale, Mathias Toft, Lasse Pihlstrom, Leonor Correia Guedes, Joaquim J Ferreira, Soraya Bardien, Jonathan Carr, Eduardo Tolosa, Mario Ezquerra, Pau Pastor, Karin Wirdefeldt, Nancy L Pedersen, Caroline Ran, Andrea C Belin, Andreas Puschmann, Carl E Clarke, Karen E Morrison, Dimitri Krainc, Matt J Farrer, Dennis Lal, Alexis Elbaz, Thomas Gasser, Rejko Krüger, Manu Sharma, Patrick May
Genome-Wide Association Study Of Copy Number Variations In Parkinson’S Disease, Zied Landoulsi, Ashwin Ashok Kumar Sreelatha, Nicole Kuznetsov, Claudia Schulte, Dheeraj Reddy Bobbili, Ludovica Montanucci, Costin Leu, Lisa-Marie Niestroj, Emadeldin Hassanin, Cloé Domenighetti, Pierre-Emmanuel Sugier, Milena Radivojkov-Blagojevic, Peter Lichtner, Berta Portugal, Connor Edsall, Jens Krüger, Dena G Hernandez, Cornelis Blauwendraat, George D Mellick, Alexander Zimprich, Walter Pirker, Manuela Tan, Ekaterina Rogaeva, Anthony Lang, Sulev Koks, Pille Taba, Suzanne Lesage, Alexis Brice, Jean-Christophe Corvol, Marie-Christine Chartier-Harlin, Eugenie Mutez, Kathrin Brockmann, Angela B Deutschländer, Georges M Hadjigeorgiou, Efthimos Dardiotis, Leonidas Stefanis, Athina Maria Simitsi, Enza Maria Valente, Simona Petrucci, Letizia Straniero, Anna Zecchinelli, Gianni Pezzoli, Laura Brighina, Carlo Ferrarese, Grazia Annesi, Andrea Quattrone, Monica Gagliardi, Lena F Burbulla, Hirotaka Matsuo, Akiyoshi Nakayama, Nobutaka Hattori, Kenya Nishioka, Sun Ju Chung, Yun Joong Kim, Lukas Pavelka, Pierre Kolber, Bart Pc Van De Warrenburg, Bastiaan R Bloem, Andrew B Singleton, Dan Vitale, Mathias Toft, Lasse Pihlstrom, Leonor Correia Guedes, Joaquim J Ferreira, Soraya Bardien, Jonathan Carr, Eduardo Tolosa, Mario Ezquerra, Pau Pastor, Karin Wirdefeldt, Nancy L Pedersen, Caroline Ran, Andrea C Belin, Andreas Puschmann, Carl E Clarke, Karen E Morrison, Dimitri Krainc, Matt J Farrer, Dennis Lal, Alexis Elbaz, Thomas Gasser, Rejko Krüger, Manu Sharma, Patrick May
Faculty, Staff and Student Publications
We investigated the role of copy number variations (CNVs) in Parkinson's disease (PD) using genotyping data from 10,815 patients (2731 early-onset PD, EOPD) and 8901 controls from the COURAGE-PD consortium. CNVs were analyzed using a sliding window genome-wide association and burden approach. No genome-wide significant CNVs were detected in the overall cohort, but a robust deletion spanning exons 2-6 of PRKN was identified in EOPD cases, validated by MLPA, and replicated in the GP2 dataset (23,089 cases, 18,824 controls). CNV burden was significantly enriched in PD-related genes, primarily driven by PRKN, with the strongest effect observed in EOPD. PRKN CNV …
Stress-Induced Il-6 Response Patterns Amplify The Link Between Daily Negative Affect And Later Depressive Symptoms During Bereavement, E Lydia Wu-Chung, Daniel L Argueta, Robert Suchting, Ryan L Brown, Michelle A Chen, Angie S Leroy, Kyle W Murdock, Cobi J Heijnen, Christopher P Fagundes
Stress-Induced Il-6 Response Patterns Amplify The Link Between Daily Negative Affect And Later Depressive Symptoms During Bereavement, E Lydia Wu-Chung, Daniel L Argueta, Robert Suchting, Ryan L Brown, Michelle A Chen, Angie S Leroy, Kyle W Murdock, Cobi J Heijnen, Christopher P Fagundes
Faculty, Staff and Student Publications
Depressive symptoms frequently follow exposure to major life stressors, such as spousal bereavement. However, long-term mental well-being varies considerably. Previously, daily negative affect significantly predicted future depressive symptoms. Higher daily negative affect may signify worse long-term mental health for individuals who also show enhanced inflammatory responses to acute stress, as heightened physiological reactivity to acute stress has been linked with increased susceptibility to depression. Among widow(er)s, we examined whether stress-induced inflammatory responses altered the magnitude of the association between daily negative affect and future depressive symptoms. In exploratory analyses, we examined whether these patterns differed between bereaved and nonbereaved adults. …
Geographical And Anatomical Microbiome Variation In Invasive Green Iguanas (Iguana Iguana), Amanda A. Diaz
Geographical And Anatomical Microbiome Variation In Invasive Green Iguanas (Iguana Iguana), Amanda A. Diaz
All HCAS Student Capstones, Theses, and Dissertations
The common green iguana (Iguana iguana) was introduced to South Florida in 1965 and has since been an especially pernicious threat both environmentally and economically. This highly invasive species is also expanding in range and populations at an astonishing rate. Understanding how this reptile is able to adapt and thrive in novel environments is of imperative need in order to begin managing their disruptive populations. Notwithstanding their negative impacts and significance, the microbiome of wild populations has not yet been characterized. Here, using 16S ribosomal RNA gene sequencing, this study is the first to characterize the microbiome composition …
Intouch Week Of April 20, 2026, New York Medical College
Intouch Week Of April 20, 2026, New York Medical College
InTouch
- Revisiting AIDS, Advocacy, and the Evolution of Medicine
- NYMC Unites for Parkinson's Disease Awareness Month
- NYMC Visits Yale's Cushing Center
- TCDM New Mexico is On-air
- In The Community: Medical Students Serve Their Communities
- In The Community: NYMC Students Provide Screenings at Community Health Fair
- Student Spotlight: Katelyn Lawson, D.P.T. Class of 2026, Shares a Journey Guided by Purpose and Shaped by Mentorship
- Faculty Profile: Shaping Future Clinicians Through Research and Connection
An Educational Intervention To Increase Nurses’ Knowledge And Confidence Of Patient Mobility, Debbie Ann Pytak
An Educational Intervention To Increase Nurses’ Knowledge And Confidence Of Patient Mobility, Debbie Ann Pytak
Walden Dissertations and Doctoral Studies
Immobility is a significant concern given that nearly half of all hospitalized adults are immobile during their hospitalization, placing them at increased risk for adverse outcomes. As a result, it is critical for nurses to implement strategies that promote safe, structured patient mobility. Thus, the purpose of this Doctor of Nursing Practice (DNP) project was to determine if an educational intervention focused on patient mobility and standardized mobility tool utilization increased knowledge and confidence among nursing staff in an acute care setting. Ten participants volunteered to attend the educational intervention. The average age of the participants was 44.30 years (SD …
The Impact Of State And Federal Policies On Academic Researchers: Findings From A National Survey, Dylan Ruediger, Chelsea Mccracken, Jonathan Barefield
The Impact Of State And Federal Policies On Academic Researchers: Findings From A National Survey, Dylan Ruediger, Chelsea Mccracken, Jonathan Barefield
Copyright, Fair Use, Scholarly Communication, etc.
Key findings
● State and federal policies targeting divisive concepts or DEI are shaping research agendas at scale and across disciplines. Twenty percent of all respondents, and 29 percent of researchers working in states with divisive concepts or similar laws, reported having avoided certain research topics because of state laws and policies.
● Eight percent of respondents representing a wide range of disciplines reported having had a federal grant cancelled in 2025.
● Eleven percent of respondents reported that federal and state policies restricting research activities are compelling them to seek employment out of state, to leave the academy, or …