Medicine and Health Sciences Commons^™

2023 July 27 - Medical Student Education Committee Called Meeting Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Global Alliance For The Promotion Of Physical Activity: The Hamburg Declaration., Jürgen M Steinacker, Willem Van Mechelen, Wilhelm Bloch, Mats Börjesson, Maurizio Casasco, Bernd Wolfarth, Carolin Knoke, Theodora Papadopoulou, Janine Wendt, Hashel Al Tunaiji, Dietrich Andresen, Olena Andrieieva, Norbert Bachl, Victoriya Badtieva, Friedhelm J Beucher, Cheri A Blauwet, Jose-Antonio Casajus Mallen, Ju-Ho Chang, German Clénin, Naama Constantini, Demitri Constantinou, Luigi Di Luigi, Lukas Declercq, Stephane Doutreleau, Svitlana Drozdovska, Martine Duclos, Andrea Ermolao, Thomas Fischbach, Anastasia N Fischer, Chiara Fossati, Jeorge Franchella, Mark Fulcher, Jan C Galle, Christian Gerloff, Evelina Georgiades, Boris Gojanovic, Marcela González Gross, Andy Grote, Martin Halle, Hans Hauner, Matthew Payton Herring, Mikio Hiura, Kerstin Holze, Gerhard Huber, David Hughes, Mark R Hutchinson, Anca Ionescu, Dina Christina Janse Van Rensburg, Anna Jegier, Natasha Jones, Kirsten Kappert-Gonther, Monika Kellerer, Yutaka Kimura, Agrita Kiopa, Bernd Kladny, Gerhard Koch, Elin Kolle, Greg Kolt, Yiannis Koutedakis, Stephan Kress, Susi Kriemler, Jens Kröger, Christian Kuhn, Roman Laszlo, Ralph Lehnert, François J Lhuissier, Kerstin Lüdtke, Shigeru Makita, Pedro Manonelles Marqueta, Winfried März, Kirill Micallef-Stafrace, Mike Miller, Melita Moore, Erich Müller, Daniel Neunhäuserer, I Renay Onur, Vahur Ööpik, Malgorzata Perl, Anastassios Philippou, Hans-Georg Predel, Sebastien Racinais, Algirdas Raslanas, Ruediger Reer, Klaus Reinhardt, Claus Reinsberger, Sandra Rozenstoka, Robert Sallis, Luis B Sardinha, Martin Scherer, Jasper Schipperijn, Romain Seil, Benedict Tan, Arno Schmidt-Trucksäss, Nils Schumacher, Bernhard Schwaab, Ansgar Schwirtz, Masato Suzuki, Jeroen Swart, Ralph Tiesler, Ulf Tippelt, Eleanor Tillet, Jane Thornton, Bulent Ulkar, Eve Unt, Evert Verhagen, Thomas Weikert, Roberto Vettor, Sheng Zeng, Richard Budgett, Lars Engebretsen, Ugur Erdener, Fabio Pigozzi, Yannis P Pitsiladis

Family Medicine Publications

Non-communicable diseases (NCDs), including coronary heart disease, stroke, hypertension, type 2 diabetes, dementia, depression and cancers, are on the rise worldwide and are often associated with a lack of physical activity (PA). Globally, the levels of PA among individuals are below WHO recommendations. A lack of PA can increase morbidity and mortality, worsen the quality of life and increase the economic burden on individuals and society. In response to this trend, numerous organisations came together under one umbrella in Hamburg, Germany, in April 2021 and signed the 'Hamburg Declaration'. This represented an international commitment to take all necessary actions to …

Urolithin A As A Potential Agent For Prevention Of Age-Related Disease: A Scoping Review., Breanne Kothe, Sarah Klein, Stephanie N. Petrosky

HPD Articles

The aging of an organism is hallmarked by systemic loss of functional tissue, resulting in increased fragility and eventual development of age-related neurodegenerative, musculoskeletal, cardiovascular, and neoplastic diseases. Growing scientific evidence points to mitochondrial dysfunction as a key contributor in the aging process and subsequent development of age-related pathologies. Under normal physiologic conditions, the body removes dysfunctional mitochondria via an autophagic process known as mitophagy. Urolithin A (UA), a metabolite produced when gut microflora digests the polyphenol compounds ellagitannin and ellagic acid, is a known inducer of mitophagy via several identified mechanisms of action. The primary objective of this scoping …

International Society Of Sports Nutrition Position Stand: Coffee And Sports Performance, Lonnie M. Lowery, Dawn E. Anderson, Kelsey F. Scanlon, Abigail Stack, Guillermo Escalante, Sara C. Campbell, Chad M. Kerksick, Michael T. Nelson, Tim N. Ziegenfuss, Trisha A. Vandusseldorp, Douglas S. Kalman, Bill I. Campbell, Richard B. Kreider, Jose Antonio

HPD Articles

Based on review and critical analysis of the literature regarding the contents and physiological effects of coffee related to physical and cognitive performance conducted by experts in the field and selected members of the International Society of Sports Nutrition (ISSN), the following conclusions represent the official Position of the Society:

(1) Coffee is a complex matrix of hundreds of compounds. These are consumed with broad variability based upon serving size, bean type (e.g. common Arabica vs. Robusta), and brew method (water temperature, roasting method, grind size, time, and equipment).

(2) Coffee’s constituents, including but not limited to caffeine, have neuromuscular, …

Promoting Positive Sexual Health Behaviors Among Rural College Students: Results Of A Targeted Sti Prevention Program, Julie Loyke

Doctoral Projects

Sexually transmitted infections (STIs) are a significant public health concern, with 26 million new cases diagnosed annually in the U.S. Emerging adults aged 18 to 25 years, which are included in the age group of Americans who have the highest rates for the three most common STIs: chlamydia, gonorrhea, and HPV (cdc.gov., 2020). Unfortunately, there is a paucity of research on the effects of STI education interventions on the attitudes and knowledge regarding STIs in this age group, especially in rural youth. While STI rates are high among adolescents and young adults nationally, rural youth have different behavioral risk factors …

Establishing Validity And Preliminary Clinical Utility Of A Behavioral Economic Measure Of Social Risk Discounting For Health Behaviors, Connor A. Burrows

Theses and Dissertations

The COVID-19 pandemic has been the most profound public health emergency of the past several decades and the United States has faced numerous challenges with the timely adoption of mitigating health behaviors. Sustained ambivalence surrounding perceptions of public health recommendations of social distancing, mask wearing, and timely vaccination remain a barrier to slowing the spread of the virus years after its initial onset. Behavior analysis and behavioral economics offer compelling theoretical and quantitative models for framing the relationship between behaviors that are aversive in the short term but beneficial for individual and public good in the long term. The present …

Michigancovid19miscdatacollection, Michigan Department Of Health & Human Services

Michigan COVID-19 MIS-C Data

This is a zipped file of all the pdfs uploaded to this collection, spanning from 2020-12-14 through 2023-04-20.

It also includes a comma separated file that lists the metadata for each file, including the file name within the Michigan COVID-19 MIS-C Data ScholarWorks Collection (ScholarWorksFileTitle), the archived URL (InternetArchiveLink), the description of the file within the Michigan COVID-19 MIS-C Data ScholarWorks Collection (ScholarWorksAbstract), and any additional comments about the file within the Michigan COVID-19 MIS-C Data ScholarWorks Collection (ScholarWorksComments).

Comments Re: Workshop On Transforming Discoveries Into Products: Maximizing Nih’S Levers To Catalyze Technology Transfer, Fred D. Ledley M.D., Edward Zhou Pharm. D, Paula Chaves Da Silva, Ph. D.

CISI Publication

We are pleased to offer written comments to this workshop focused on “… making federally funded inventions more accessible to the public… .” These comments are informed by recent research from the Center for Integration of Science and Industry at Bentley University that has:

• Quantified the scope of NIH funding for basic or applied research, clinical development, or patents associated with drugs approved by the FDA 2010-2019. This work identified $187 billion in NIH-funded research directly related to these drugs (applied research – 17%) or their biological targets (basic research – 83%), representing a (discounted) investment comparable to reported levels …

Early Stage Or Curable Cancer Diagnoses In Minorities: A Journey Of Survivors, Lora Asberry

Master of Science in Integrative Biology Theses

Patients diagnosed with early-staged or curable forms of cancer experience physical, as well as, mental challenges associated with disease progression and treatment. Previous studies have demonstrated that minorities and underrepresented communities did not receive the same level of care in comparison to their non-minority counterparts. Previous studies have also demonstrated that health disparities among minorities affected their cancer journey. This study addressed: how medical disparities varied between minorities and non-minorities, the overall effects of the cancer diagnoses in minorities compared to non-minorities, whether these perspectives differed in male vs. female participants, and whether there were any possible communication barriers between …

Increasing Character Strength Knowledge, Interest, And Skill: Preliminary Evidence For A Collaborative And Multimethod Assessment Procedure, Jeff J. Klibert, Michaela D. Simpson, Brandon J. Weiss, C. Thresa Yancey, Calla Pritulsky, Amy Luna, Hayley Houseman, Hani M. Samawi

Psychology: Faculty Publications

Introduction: The study’s objective was to evaluate whether a qualitative, collaborative, and multimethod assessment protocol increased reports of character strength interest, knowledge, and perceived skills.

Methods: Thirty-two participants completed three phases of data collection. Participants were first screened for well-being, which was used as an auxiliary covariate to order participants into experimental conditions. Selected participants were randomly assigned to a control or collaborative and multimethod assessment (card sort × qualitative interview) condition. Participants completed pre- and post-measures of strength interest, knowledge, and perceived skill. In the final phase, second phase participants were invited to report on strength-related outcomes 24 h …

Genetics Of Functional Seizures; A Scoping Systematic Review, Ali A. Asadi-Pooya, Mark Hallett, Nafiseh Mirzaei Damabi, Khatereh Fazelian Dehkordi

Department of Neurology Faculty Papers

Background: Evidence on the genetics of functional seizures is scarce, and the purpose of the current scoping systematic review is to examine the existing evidence and propose how to advance the field.

Methods: Web of science and MEDLINE were searched, from their initiation until May 2023. The following key words were used: functional neurological disorder(s), psychogenic neurological disorder(s), functional movement disorder(s), psychogenic movement disorder(s), functional seizures(s), psychogenic seizure(s), nonepileptic seizure(s), dissociative seizure(s), or psychogenic nonepileptic seizure(s), AND, gene, genetic(s), polymorphism, genome, epigenetics, copy number variant, copy number variation(s), whole exome sequencing, or next-generation sequencing.

Results: We identified three original studies. …

Tp53 Induced Glycolysis And Apoptosis Regulator And Monocarboxylate Transporter 4 Drive Metabolic Reprogramming With C-Myc And Nfkb Activation In Breast Cancer, Megan E. Roche, Ying-Hui Ko, Marina Domingo-Vidal, Zhao Lin, Diana Whitaker-Menezes, Ruth C. Birbe, Madalina Tuluc, Balázs Győrffy, Jaime Caro, Nancy J. Philp, Ramon Bartrons, Ubaldo Martinez-Outshoorn

Department of Medical Oncology Faculty Papers

Breast cancer is composed of metabolically coupled cellular compartments with upregulation of TP53 Induced Glycolysis and Apoptosis Regulator (TIGAR) in carcinoma cells and loss of caveolin 1 (CAV1) with upregulation of monocarboxylate transporter 4 (MCT4) in fibroblasts. The mechanisms that drive metabolic coupling are poorly characterized. The effects of TIGAR on fibroblast CAV1 and MCT4 expression and breast cancer aggressiveness was studied using coculture and conditioned media systems and in-vivo. Also, the role of cytokines in promoting tumor metabolic coupling via MCT4 on cancer aggressiveness was studied. TIGAR downregulation in breast carcinoma cells reduces tumor growth. TIGAR overexpression in carcinoma …

Prevalence, Management And Efficacy Of Treatment In Portal Vein Obstruction After Paediatric Liver Transplantation: Protocol Of The Retrospective International Multicentre Portal Registry., Bader A. Alfares, Hubert P J Van Der Doef, Barbara E. Wildhaber, Thomas Casswall, Greg Nowak, Martin Delle, Denise Aldrian, Valeria Berchtold, Georg F. Vogel, Piotr Kaliciński, Malgorzata Markiewicz-Kijewska, Adam Kolesnik, Jesús Q. Bernabeu, María Mercadal Hally, Mauricio Larrarte K, Paolo Marra, Michela Bravi, Domenico Pinelli, Mureo Kasahara, Seisuke Sakamoto, Hajime Uchida, Vidyadhar Mali, Marion Aw, Stéphanie Franchi-Abella, Emmanuel Gonzales, Florent Guérin, Guillermo Cervio, Julia Minetto, Sergio Sierre, Martin De Santibañes, Victoria Ardiles, Jimmy Walker Uno, Helen Evans, David Duncan, John Mccall, Steffen Hartleif, Ekkehard Sturm, Jai Patel, Marumbo Mtegha, Raj Prasad, Cristina T. Ferreira, Luiza S. Nader, Marco Farina, Catalina Jaramillo, Manuel I. Rodriguez-Davalos, Peter Feola, Amit A. Shah, Phoebe M. Wood, Michael R. Acord, Ryan T. Fischer, Bhargava Mullapudi, Richard J. Hendrickson, Rajeev Khanna, Viniyendra Pamecha, Amar Mukund, Khalid Sharif, Girish Gupte, Simon Mcguirk, Gilda Porta, Marco Spada, Tommaso Alterio, Giuseppe Maggiore, Winita Hardikar, Marisa Beretta, Rudi Dierckx, Ruben H J De Kleine, Reinoud P H Bokkers

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: Portal vein obstruction (PVO) consists of anastomotic stenosis and thrombosis, which occurs due to a progression of the former. The aim of this large-scale international study is to assess the prevalence, current management practices and efficacy of treatment in patients with PVO.

METHODS AND ANALYSIS: The Portal vein Obstruction Revascularisation Therapy After Liver transplantation registry will facilitate an international, retrospective, multicentre, observational study, with 25 centres around the world already actively involved. Paediatric patients (agedyears) with a diagnosed PVO between 1 January 2001 and 1 January 2021 after liver transplantation will be eligible for inclusion. The primary endpoints are …

A Phase Ii Clinical Trial Of Pembrolizumab Efficacy And Safety In Advanced Renal Medullary Carcinoma, Chijioke Nze, Pavlos Msaouel, Mohamed H Derbala, Bettzy Stephen, Abdulrahman Abonofal, Funda Meric-Bernstam, Nizar M Tannir, Aung Naing

Faculty, Staff and Student Publications

Background: Renal medullary carcinoma (RMC) is one of most aggressive renal cell carcinomas and novel therapeutic strategies are therefore needed. Recent comprehensive molecular and immune profiling of RMC tissues revealed a highly inflamed phenotype, suggesting the potential therapeutic role for immune checkpoint therapies. We present the first prospective evaluation of an immune checkpoint inhibitor in a cohort of patients with RMC.

Methods: A cohort of patients with locally advanced or metastatic RMC was treated with pembrolizumab 200 mg intravenously every 21 days in a phase II basket trial (ClinicalTrials.gov: NCT02721732). Responses were assessed by irRECIST. Tumor tissues were evaluated …

Building A Community-Academic Partnership To Improve Underrepresented Group Awareness Of Parkinson’S Disease And Research, Danielle N. Larson, Jennifer Adrissi, Madison Lyleroehr, Emily Zivin, Karen Williams, Tanya Simuni

Journal of Health Disparities Research and Practice

BACKGROUND: Members of underrepresented groups (URGs) are more likely to have delays in PD diagnosis and less likely to receive specialized care when compared to non-Hispanic Caucasians. URGs are not proportionately represented in PD clinical research. Barriers to optimal diagnosis and treatment and research participation are multifaceted but include insufficient community knowledge of PD and research.

OBJECTIVES: To establish a community-academic partnership (CAP) for increasing knowledge of Parkinson’s Disease (PD) and research opportunities in underrepresented Chicago communities. Here, we describe the development, structure, and outcomes of this pilot program.

METHODS: The Chicago Movement Coalition (CMC) was established with academic leaders …

Does Using Sofa Score For Ventilator Triage Among Covid 19 Patients Result In Suboptimal Allocation Of Medical Ventilators For The Bipoc Population?, Alexandrea Mp Masocco, Elisabeth Michel, Ebbin Dotson

Journal of Health Disparities Research and Practice

Introduction: Since the COVID-19 pandemic in the United States, Black, and Latinx populations have been disproportionately affected by the COVID-19 pandemic. It can be inferred with high confidence that those most vulnerable are the least likely to receive essential care. Kidney transplant allocation and COVID-19 triage protocols share commonalities in that both protocols involve using multivariate scored criteria with objective and subjective inputs. As such, the similar conclusion in outcomes is concerning. It is worth questioning whether the racial inequalities demonstrated in the COVID-19 pandemic related to access to life-saving ventilators were associated with triage protocols.

Methodology: Using an exploratory …

Perspectives On Flu Vaccination Advertisement Messaging In The Era Of Covid-19: Thematic Analysis Centering Adult Black Voices, Krissy Moehling Geffel, Stephanie N. Christian, Andrea D. Casas, Harika P. Dyer, Tiffany L. Gary-Webb, Hannah E. Hardy, Roderick Harris, Dara D. Mendez

Journal of Health Disparities Research and Practice

Influenza (flu) is an infectious, respiratory disease that causes substantial burden and mortality, and Non-Hispanic Black people experience profound disparities in flu disease burden in the United States. One contributor to flu disease disparities is lower flu vaccination rates among Black populations. This qualitative study was conducted during the COVID-19 pandemic and used the Public Health Critical Race Praxis framework to center and elicit Black adults’ perspectives of desired flu vaccine messaging. This work builds upon efforts to increase access to flu vaccinations and recommendations are provided to aid in tailoring flu vaccine messaging via a health equity lens. Recommendations …

Diabetes Related Distress And Co-Occurrence With Depressive Symptoms In Urban Low-Income African American And Hispanic/Latinx Adults With Type 2 Diabetes, Laurie Ruggiero, Sarah Williams Leng, Mary De Groot, Ben S. Gerber, Rosalba Hernandez, Lauretta Quinn

Journal of Health Disparities Research and Practice

Introduction. Burden of diabetes in the U.S. is greater in racial-ethnic minority populations than non-Hispanic Whites. Depression and diabetes-related distress (DRD) are recognized as relatively common and important psychosocial areas to address in people living with diabetes. Limited research in the U.S. has focused on DRD in racial-ethnic minority populations. The purpose of this study is to describe patterns of DRD and co-occurrence with depressive symptoms in urban low-income African American and Hispanic/Latinx adults with type 2 Diabetes Mellitus (T2DM).

Method. We examined the baseline data collected for a randomized clinical trial (RCT) studying the impact of a culturally tailored …

Supporting Minority Serving Institution Faculty To Enhance Biomedical Research: The Csulb Center For Health Equity Research Institute, Laura H. D'Anna, Thomas Alex Washington, Wendy Nomura

Journal of Health Disparities Research and Practice

Scientists from Minority Serving Institutions (MSIs) bring unique perspectives and experiences that enhance the potential for understanding factors that are associated with racial, ethnic, and social inequities in health and health status. However, inadequate research infrastructure and mentoring opportunities within MSIs limit faculty engagement in the research enterprise. Additionally, structural inequities embedded in the NIH grant funding process disproportionately disadvantage underrepresented minority (URM) faculty and faculty at MSIs. The foci of the intensive Center for Health Equity Research (CHER) Institute were to 1) increase the number of early career faculty members (with an emphasis on MSI faculty) who are better …

Socioeconomic Disparities Exist In Access To Rotator Cuff Repair Surgery, Justin Solarczyk, Heather Roberts Md, Stephanie Wong Md, Derek Ward Md

Journal of Health Disparities Research and Practice

Background: The relationship of socioeconomic disparity in access to rotator cuff repair (RCR) has not been well studied. Socioeconomic, racial, and ethnic disparities in access to surgical management of rotator cuff tears have previously been described in patients with commercial insurance. This study is a population-level analysis which investigates racial and ethnic disparities in access to surgical rotator cuff repair across multiple health insurance statuses.

Purpose: (1) Is non-white race and ethnicity associated with lower rates of RCR? (2) Do these associations change throughout different insurance statuses?

Methods: We used the Healthcare Cost and Utilization Project (HCUP) database to identify …

Cardiovascular Disease In Saudi Arabia: Facts And The Way Forward, Adel Abdulkader Tash, Rasha Fahad Al-Bawardy

Journal of the Saudi Heart Association

While some risk factors for cardiovascular diseases (CVDs) are non-modifiable, other determinants like obesity, hypertension, type-2 diabetes and dyslipidemia can be mitigated by a wide plethora of measures to control CVD morbidity/mortality. Those determinants have been on the rise in Saudi Arabia, exacerbated by sedentary lifestyle. The Saudi Vision 2030 focuses include the reduction of CVD clinical and economic burden to scale-up vitality and longevity; in a new era of comprehensive healthcare. From a health economics standpoint, CVDs entail a burden on healthcare systems directly through expenditure and indirectly through years living with the disease, low productivity, premature morbidity and …

Improved Super-Elastic Ti-Ni Alloy Wire For The Treatment Of Skeletal Class Iii With Unilateral Buccally Positioned High Canine, Yi-Mien Cheng, Chih-Chieh Lin, Yu-Cheng Lo, Yuan-Hou Chen, Jian-Hong Yu

Taiwanese Journal of Orthodontics

A 20-year-old male adult came to the clinic with a chief complaint of poor dental alignment. Clinical examination had revealed Skeletal Class III with an upper right buccally positioned high canine, anterior crowding, midline deviation and both maxillary lateral incisors crossbite. Four bimaxillary premolars were extracted. Improved super-elastic Ti-Ni alloy wire (ISW, developed by Tokyo Medical and Dental University) leveling was performed to relieve the crowding and to correct the high canine and midline deviation. Intermaxillary elastics (IME) was applied for a better interdigitation. Treatment was completed within 29 months and a desirable occlusion was achieved.

Clear Aligner Treatment In An Adolescent Female With Hyperdivergent Growth Pattern Of The Mandible, Chih-Jan Chen, Yu-Ling Cheng, Yuen-Yung Tsang, Huei-Mei Tsai, Yi-Min Liu

Taiwanese Journal of Orthodontics

This study investigated the application of a clear aligner system in treatment of an adolescent Taiwanese female exhibiting a high mandibular plane angle, with a particular emphasis on the alignment of crowded upper anterior teeth. The treatment plan excluded tooth extraction and applied sequential distalization and transverse expansion across both dental arches instead. The alleviation of crowding and increased arch width was accomplished, while maintaining optimal vertical dimension control. The treatment yielded observable improvements in both oral function and aesthetic appearance

Bilateral Maxillary Canine Substitution With High Impaction In The Center Of Anterior Palate, Chien-Man Chang, Ying-Chen Chen, Ellen Wen-Ching Ko

Taiwanese Journal of Orthodontics

This case report described the treatment of a 16 y/o female who was referred for her bilateral maxillary impacted canines. Her chief complaint also involved lower crooked front teeth. She presented with skeletal Class I with orthodivergent facial pattern and dental Class II relationship. Clinical oral examination revealed two peg lateral incisors and two retained primary canines in the upper arch. The panoramic film showed two maxillary impacted canines near the center of palate. Before the orthodontic intervention, surgical exposure was conducted with open window technique. A transpalatal arch with 2 soldered hooks was inserted as anchorage for distal traction …

Surgical-Orthodontic Correction Of Skeletal Class Iii Anterior Open Bite With Facial Asymmetry, Hao-Hsiang Chang, Cheng-Hui Lin, Ellen Wen-Ching Ko

Taiwanese Journal of Orthodontics

Class III anterior open bite (AOB) is characterized by mandibular downward movement with anteroposterior discrepancy and long face deformity. This often leads to esthetic and functional problem that decrease the Quality of Life in patients. Treatment decision of AOB is always challenging whether goes for camouflage therapy or orthognathic surgery. A 26-year-old female suffered from anterior open bite and facial asymmetry. The clinical and radiographic examination revealed skeletal Class III relationship with hyperdivergent facial type, facial asymmetry with chin deviation to right, and AOB of -5 mm overbite. The pre-surgical orthodontic treatment included partial anterior retraction of upper anterior teeth …

Orthodontic Retreatment Of Class Ii Division 2 Malocclusion With Deep Bite And Gummy Smile Using Miniscrews, Hsin-Yi Lo, Hung-Jen Wang, Yu-Lian Lin

Taiwanese Journal of Orthodontics

Orthodontic treatment of Class II Division 2 malocclusion with gummy smile and deep bite is a challenge under the circumstances of lacking skeletal anchorage device. In this case report, we illustrated a miniscrew-assisted orthodontic retreatment of a 29-year-old female patient, who came to our department with a chief complaint of her unpleasant smile. The patient had previously undergone orthodontic treatment with 4-bicuspid extractions to correct her protrusive incisors. The clinical examination revealed a Class II division 2 malocclusion, 100% overbite, and a gummy smile. The philosophy of the orthodontic retreatment in this case was to correct Class II molar relationship …

A Review On Anatomical And Surgical Importance Of Mammary Gland, Sneha Jm Sneha Jm Dr, Pushpa Nb Dr, Vidya Cs Dr, Manjappa M Dr

Digital Journal of Clinical Medicine

ABSTRACT

The mammary gland is an exocrine gland present in female mammals responsible for the production and secretion of milk during the process of lactation. It is mainly composed by epithelial cells and adipocytes. The features that make mammary gland unique are 1) its highly plastic properties displayed during pregnancy, lactation and involution (all steps belonging to the lactation cycle) and 2) its requirement to grow in close association with adipocytes which are absolutely necessary to ensure mammary gland development at puberty and remodelling during the lactation cycle. (Georgia colleluori, Jessica perugini, Giorgio barbatelli, and saverio cintr (2021).

Conclusion

The …

Antimicrobial Stewardship Programs: The Unique Challenges Of Implementation In The Emergency Department, Anders Ahlberg, Callen H. Morrison

URGENT Matters

No abstract provided.

Investigating The Physiological Mechanisms Between Resistance Training And Pain Relief In The Cancer Population: A Literature Review, Yvonne Jiang, Peter C. Angeletti, Amy J. Hoffman

Nebraska Center for Virology: Faculty Publications

This literature review examines the mechanisms of how exercise, specifically in the form of resistance training, may lead to pain relief in the cancer population. Primary data from three different cancer populations: breast, prostate, and lung, will be examined. A number of experimental studies have been conducted to confirm the effectiveness of resistance training on pain relief as well as the biochemical pathways that relate to this process. In this review, we will examine 5 randomized controlled trials. For the purposes of this review, pain is defined as physical suffering or discomfort associated with illness. Pain is the body’s natural …

Surface-Doped Zinc Gallate Colloidal Nanoparticles Exhibit Ph-Dependent Radioluminescence With Enhancement In Acidic Media, Navadeep Shrivastava, Jessa Guffie, Tamela L Moore, Burak Guzelturk, Amar S Kumbhar, Jianguo Wen, Zhiping Luo

Faculty, Staff and Student Publications

As abnormal acidic pH symbolizes dysfunctions of cells, it is highly desirable to develop pH-sensitive luminescent materials for diagnosing disease and imaging-guided therapy using high-energy radiation. Herein, we explored near-infrared-emitting Cr-doped zinc gallate ZnGa2O4 nanoparticles (NPs) in colloidal solutions with different pH levels under X-ray excitation. Ultrasmall NPs were synthesized via a facile hydrothermal method by controlling the addition of ammonium hydroxide precursor and reaction time, and structural characterization revealed Cr dopants on the surface of NPs. The synthesized NPs exhibited different photoluminescence and radioluminescence mechanisms, confirming the surface distribution of activators. It was observed that the colloidal NPs emit …