Medicine and Health Sciences Commons^™

Topiramate (Topamax): Evolving Role In Weight Reduction Management: A Narrative Review, Irza Wajid, Alexis Vega, Katherine Thornhill, Jack Jenkins, Chandler Merriman, Debbie Chandler, Sahar Shekoohi, Elyse M. Cornett, Alan D. Kaye

School of Medicine Faculty Publications

Obesity has emerged as a widespread disease with epidemic proportions, necessitating effective management to enhance the overall health outcomes of patients. Medical intervention for weight loss becomes necessary when diet and exercise prove ineffective, and topiramate emerges as a potential treatment option for this global problem. Currently approved as an anti-epileptic and migraine prophylaxis medication, topiramate is frequently utilized as adjunctive therapy for patients with mood and eating disorders, as well as for alcohol use disorders. Its multifaceted mechanisms of action contribute to reducing neuronal excitation and enhancing neuronal inhibition. Given its variety of mechanisms, topiramate shows several off-label outcomes, …

Comparative Polar And Lipid Plasma Metabolomics Differentiate Kshv Infection And Disease States, Sara R. Privatt, Camila Pereira Braga, Alicia Johnson, Salum J. Lidenge, Luke Berry, John R. Ngowi, Owen Ngalamika, Andrew G. Chapple, Julius Mwaiselage, Charles Wood, John T. West, Jiri Adamec

School of Medicine Faculty Publications

Background: Kaposi sarcoma (KS) is a neoplastic disease etiologically associated with infection by the Kaposi sarcoma-associated herpesvirus (KSHV). KS manifests primarily as cutaneous lesions in individuals due to either age (classical KS), HIV infection (epidemic KS), or tissue rejection preventatives in transplantation (iatrogenic KS) but can also occur in individuals, predominantly in sub-Saharan Africa (SSA), lacking any obvious immune suppression (endemic KS). The high endemicity of KSHV and human immunodeficiency virus-1 (HIV) co-infection in Africa results in KS being one of the top 5 cancers there. As with most viral cancers, infection with KSHV alone is insufficient to induce tumorigenesis. …

Cerebellar Interneurons Control Fear Memory Consolidation Via Learning-Induced Hcn Plasticity, Kathryn Lynn Carzoli, Georgios Kogias, Jessica Fawcett-Patel, Si-Qiong J. Liu

School of Medicine Faculty Publications

While synaptic plasticity is considered the basis of learning and memory, modifications of the intrinsic excitability of neurons can amplify the output of neuronal circuits and consequently change behavior. However, the mechanisms that underlie learning-induced changes in intrinsic excitability during memory formation are poorly understood. In the cerebellum, we find that silencing molecular layer interneurons completely abolishes fear memory, revealing their critical role in memory consolidation. The fear conditioning paradigm produces a lasting reduction in hyperpolarization-activated cyclic nucleotide-gated (HCN) channels in these interneurons. This change increases intrinsic membrane excitability and enhances the response to synaptic stimuli. HCN loss is driven …

Healthcare Providers’ Perceptions Of Deaf-Hearing Interpreter Teams: Impact Of Interpreting Approaches, Julayne Feilbach

Journal of Interpretation

This study explores the perceptions and preferences of healthcare providers who work with Deaf Interpreter-Hearing Interpreter (DI-HI) teams. Healthcare providers depend on interpreters' ability to bridge the communication and cultural gap to assess and treat patients accurately. Although there have been studies on healthcare providers’ perceptions of interpreters to date, none of the research explores the impact of healthcare providers’ perceptions on their experiences with DI-HI teams. To address this, interviews with nine healthcare practitioners were conducted. As part of the interview, participants were shown a video of two interpreting samples to illustrate different approaches to interpreting. Data were analyzed …

(2011) Test Questions For Licensed Professional Counselors, Test Questions

Louisiana Journal of Counseling

No abstract provided.

(2011) Counseling Young People With Ptsd, David Hurlburt, Bill Mchenry, Darren E. Dobrinski

Louisiana Journal of Counseling

PTSD is a prevalent and significant disorder that affects the lives of many youth. Targeted interventions should address both the symptoms of PTSD as well as the precursory events that lead to the diagnosis. Counselors should be aware of the many possible sources of traumatizing events such as threats of death, sexual abuse, severe neglect, and environmental factors (e.g., hurricanes/tornadoes). This article informs counselors of the prevalence of PTSD, treatment options and characteristics of PTSD in children and teens.

(2011) Batterer Intervention Programs: The Relationship Between Session Completions And The Batterer’S Perception Of The Abusive Relationship, John P. Muldoon

Louisiana Journal of Counseling

The purpose of this study is to investigate the male batterer’s perception of his relationship with his partner and the impact the relationship has on session attendance and program completion in a batterer intervention program. The study investigated 198 male participants enrolled in a batterer intervention program in the southeastern United States. The findings suggest a complex interaction among the three variables of (1) the participant’s perception of the referral incident, (2) the batterer’s emotional commitment to the victim, and (3) the total number of sessions completed in a batterer intervention program. The implications of demographic and psychological variables affecting …

(2011) Grandparents Raising Grandchildren: The Effects, Counseling Challenges, And Strategies, Harriet A. Bachner

Louisiana Journal of Counseling

For more than 20 years the number of grandparents who have taken over the role of the primary custodial caregiver of their grandchildren has steadily increased. There has been burgeoning investigation and interest into this phenomenon that affects the largest segment of the U.S. population, the baby boom generation, as well as older adults. This report provides an overview of the most critical issues that have been covered in the literature and identifies some of the challenges for counselors who work with both the grandparents and the children. Some counseling strategies that have been shown to be promising in dealing …

(2011) College Students’ Perceptions Of The Mental Health Needs For Fellow Students Returning From Iraq And Afghanistan: Implications For Collegecounselors, Theodore S. Smith, Danielle M. Mcclendon, Kristy D. Fusilier

Louisiana Journal of Counseling

After participating in a series of lectures on military service and mental health, 115 college students wrote an essay addressing their perception of the mental health needs for fellow students following deployment. A content analysis of the students’ essays was completed, as the foundation for the present study. Information was obtained from the content analysis regarding the number of cohorts returning, psychological overlay, factors contributing to continued counseling after a first visit, and best provider of counseling services. Results are applied to the provision of counseling services in collegesettings.

(2011) From The Editors, Meredith Nelson, Peter Emerson, Mary Emily Matbery

Louisiana Journal of Counseling

Refections on Scholarship: Getting Started Doing Research

(2011) Entire Issue, Meredith Nelson, Peter Emerson

Louisiana Journal of Counseling

No abstract provided.

Eplerenone Crystal Nanosuspension For Solubility Enhancement: Preparation And Evaluation, Hawraa K. Khafeef, Nawal A. Rajab

Maaen Journal for Medical Sciences

Eplerenone is an aldosterone receptor inhibitor utilized for management of hypertension and chronic heart failure. However, it’s low solubility and dissolution-dependent absorption lead to reduced oral bioavailability (The absolute bioavailability of eplerenone is 69%). This study aimed to develop and optimize eplerenone nanosuspension (EPLNS) to enhance its solubility and improve dissolution rate. The nanosuspension (NS) was produced using the solvent anti-solvent precipitation method, and an investigation was conducted to assess the effect of variables such as stabilizer type, stabilizer concentration, and stirring rate on particle size (PS) and polydispersity index (PDI). The results showed that most of the prepared EPLNS …

(2012) Test Questions For Licensed Professional Counselors, Test Questions

Louisiana Journal of Counseling

No abstract provided.

(2012) Enhancing Child Parent Relationships Using Child Parent Relationship Therapy (Cprt), Erin M. Dugan

Louisiana Journal of Counseling

Child-Parent Relationship Therapy (CPRT) has been growing in research over the past few years. Studies have indicated that CPRT is an effective approach to enhancing the child-parent relationship (Landreth & Bratton, 2006; Edwards, Sullivan, Meany-Walen, Kantor, 2010; Sheely-Moore & Ceballos, 2011). CPRT encourages parents to strengthen and enhance their relationships with their child(ren) based on the development of increased levels of empathy and acceptance. Although there have been quantitative studies conducted to study the effectiveness of CPRT, limited studies have researched qualitative outcomes. This pilot study measures qualitative outcomes of one group of participants over ten sessions using pre/post test …

(2012) Analysis Of Author And Topic Trends For The Louisiana Journal Of Counseling (Ljc), Cassandra Guillaume, Shauna Russell, Meredith Nelson, Peter Emerson

Louisiana Journal of Counseling

This review will attempt to shed light upon the historical evolution of the Louisiana Journal of Counseling (LJC) by conducting a qualitative analysis of its published articles for the years 1999, 2001-2004, and 2006-2011. In order to conduct this analysis, we noted major author trends including: gender, professional title, and regional affiliation. In addition, we also highlighted five major subject areas that have emerged over the years, including: counselor identity, professional issues, counselor education and supervision, research and counseling techniques, and multiculturalism. From this analysis, we predicted possible future directions for this journal and highlighted some of the major findings.

(2012) Internal Working Models: A Strategy For Enhancing Counselor Supervision, Jennifer R. Curry, Glenn W. Lambie

Louisiana Journal of Counseling

Internal Working Models (IWMs) (Bowlby, 1988) provide a viable framework for conceptualizing supervisees’ development within the counselor supervision process. IWMs are the intrapersonal schematic for an individual’s interpersonal relations and significantly influence a supervisee’s interactional dynamics, development, and wellness within the context of both the therapeutic and supervisory relationships. Additionally, IWMs may be utilized within counseling supervision as a strategy to explore a supervisee’s theoretical orientation, case conceptualization, and the transference of theory to practice. This article introduces a supervision strategy grounded in IWMs to support supervisees’ development and offers a case illustration of the tool.

(2012) Group Physical Exercise, Relationship Dynamics, And Curative Factors: Qualitative Findings From A Kinesiology Exercise Immunology Course, Laura Fazio-Griffith, Jennifer R. Curry

Louisiana Journal of Counseling

Qualitative inquiry was used to examine students’ perceptions of, and experiences in, a Kinesiology Exercise Immunology Course with an experiential marathon training component. Twenty-eight students participated in four focus groups. Data was analyzed according to the themes and patterns that emerged during each focus group. Major themes revealed the presence of, relationship dynamics, interpersonal learning, and multiple curative factors used to develop and enhance the relationship of the educator and student the experiential classroom setting. Implications and recommendations for human service educators are discussed.

On-Line Discussions About Self-Injury And Suicide, Jennifer Marshall, Trey Fitch

Louisiana Journal of Counseling

College students were surveyed regarding their use of websites and BLOG/discussion boards that promote and/or discourage and treat suicidal and self-injurious behavior. The students surveyed related that they were more likely to use websites and BLOG/discussion boards that discourage and treat suicidal and self-injurious behaviors. The results also indicated that the respondents had a higher percentage of response to acknowledging that peers have been influenced by websites/discussion boards/BLOGS that encourage suicidal and self-injurious behaviors. Overall, these findings support the notion that the viewing of harmful self-injury websites is not widespread.

(2012) From The Editors, Meredith Nelson, Peter Emerson, Mary Emily Matbery

Louisiana Journal of Counseling

Counselor Self Care: Management of Self

(2012) Entire Issue, Meredith Nelson, Peter Emerson

Louisiana Journal of Counseling

No abstract provided.

A Case Of Fournier’S Gangrene: A Rare, Lethal Skin Infection, Aditi Chokshi, Laura Ziton

HPD Articles

Fournier’s gangrene (FG) is a rare form of necrotizing fasciitis that is characterized by fascial necrosis of the genitalia or perineum. FG typically results as a complication of genital or anorectal abscess, pressure sore, or surgical site infections. Many patients present with no symptoms, whereas other patients may present with non-specific symptoms such as pain or erythema in the genital or perianal regions. We present a case of FG in a 76-year-old male. Our patient presented initially with only complaints of perianal and groin pain. Upon imaging and skin examination, a diagnosis of Fournier’s gangrene was made. However, due to …

Bertumbuh Berkembang: Aktivitas & Lembar Evaluasi—Modul Pemberian Makan Bayi Dan Anak (Pmba), Hikmah Kurniasari

Pengembangan Profesional

Bagian lampiran dari Modul PMBA ini berisikan ide aktivitas untuk dilakukan oleh kader Posyandu beserta orang tua/pengasuh anak, lembar evaluasi, serta refleksi modul untuk tiap-tiap bab. Lampiran ini juga dilengkapi dengan arahan untuk melakukan curah pendapat, diskusi kelompok, juga latihan kasus.

Students' Attitudes, Beliefs And Perceptions Surrounding 2slgbtqia + Health Education And Inclusiveness In Canadian Physiotherapy Programs, Codie A Primeau, Holly T Philpott, Kyle Vader, Janelle Unger, Christina Y Le, Trevor B Birmingham, Joy C Macdermid

Physical Therapy Publications

BACKGROUND: Patients who identify as 2SLGBTQIA + report negative experiences with physiotherapy. The objectives were to evaluate student attitudes, beliefs and perceptions related to 2SLGBTQIA + health education and working with individuals who identify as 2SLGBTQIA + in entry-level physiotherapy programs in Canada and to evaluate physiotherapy program inclusiveness towards 2SLGBTQIA + persons.

METHODS: We completed a nationwide, cross-sectional survey of physiotherapy students from Canadian institutions. We recruited students via email and social media from August-December 2021. Frequency results are presented with percentages. Logistic regression models (odds ratios [OR], 95%CI) were used to evaluate associations between demographics and training hours …

Piloting A Peer Support Program For Patients Who Screen Positive For Intimate Partner Violence, Suicidal Ideation, And Depression, Michelle Drouin, Mindy Flanagan, Jeanne Carroll, Connie Kerrigan, Heather Henry, Tammy Toscos

Health Services and Informatics Research

Peer support programs have been utilized for a variety of mental-health-related needs, including suicidality and depression. In this pilot program, we developed a peer support network to address multimorbidity involving intimate partner violence (IPV), suicidal ideation, and depression. Over one year, our Suicide Obviation Support (SOS) navigators enrolled and provided at-elbow support to 108 patients (67.6% women) who screened positive for IPV, many of whom also screened at moderate or high risk for suicidality (64.8%) and/or exhibited depression symptoms. At a 6-month follow-up, 63 participants (58.3%) were retained. Those who stayed enrolled in the program for six months were less …

Individual And Combined Effect Of Eudragit® Rs 100 And Eudragit® Rl 100 On Sustained Release Characteristics Of Ropinirole Hcl-Loaded Microparticles, Aamir Hayyat, Nabeel Siddique

Pharmaceutical Sciences and Research

Ropinirole HCl is a non-ergoline dopamine agonist which is recommended for the treatment of both Parkinson’s disease and Restless Legs Syndrome (RLS). Its half-life is about 6 hours and it is metabolized in the liver primarily by CYP1A2. Its metabolites are water-soluble and rapidly excreted from the body in urine. However, its oral bioavailability is low. Therefore, this current project aimed to produce and evaluate sustained release ropinirole microparticles coated with Eudragit^® RS 100 and RL 100 by varying polymer types and concentrations. Ropinirole microparticles were prepared by oil in oil emulsion solvent evaporation technique. Emulsifier concentration was constantly …

Association Between Acculturation, Dental Floss Use, Dental Visits And Unmet Dental Needs Among Asians In The United States: Findings From National Health And Nutrition Examination Survey (Nhanes) 2011–2018, Ting Luo, Kaylin Beiter, Tung Sung Tseng

School of Graduate Studies Faculty Publications

Objectives: The objectives of this study were to examine the associations between acculturation and dental floss, regular dental visits and unmet dental care needs among Asian Americans, as well as the moderating effects of these associations. Methods: This study analysed national representative samples from the National Health and Nutrition Examination Survey (NHANES) 2011–2018. A total of 2763 Asian Americans aged 20 and older were included in this analysis. The primary predictor, acculturation score, was determined by three questions: (i) language spoken at home (higher score for English), (ii) country of birth (higher score for United States) and (iii) length of …

50 Years After The Bunker Hill Mine Fire Caused One Of The Largest Lead-Poisoning Cases In Us History, Idaho’S Silver Valley Is Still At Risk, Martin Schiavenato

Nursing Faculty Scholarship

On Sept. 3, 1973, a fire swept through the baghouse of the Bunker Hill mine in Idaho’s Silver Valley. The building was designed to filter pollutants produced by smelting, the melting of rocks that separates metal from its ore. The gases produced in this process carried poisons, including lead.

At the time, the prices of lead and silver were climbing toward all-time highs. Rather than wait for new filters and repairs, company officials kept the mine running. They increased production, bypassed the filtration steps and, for eleven months, dumped noxious gases directly into the surrounding area.

Then, horses …

Using Ai For Diagnosis And Treatment Plan, Andrea Guthridge

AI Assignment Library

This assignment is to be used for Undergraduate Medical Education Training to consider the role of AI by patients and aspiring physicians. Students will comparing and contrast three self-diagnostic tools WebMD, ChatGPT, and Bard with a case study to determine a diagnosis and treatment plan. Additionally, students will consider concerns, benefits, privacy and accuracy, and how this will impact their practice as physicians.

Partner Discussion Using An Ehr And Chatgpt, Anne Bodensteiner

AI Assignment Library

This assignment requires students to complete a worksheet using a simulated EHR (which is a subscription software purchase) and meet with a partner to discuss AI in nutrition care and compare their results to the worksheet with answers they get from ChatGPT.

Atmospheric Pressure Plasma Treatment Of Skin: Penetration Into Hair Follicles, Kseniia Konina, Theresa A. Freeman, Mark J. Kushner

Department of Orthopaedic Surgery Faculty Papers

Sterilization of skin prior to surgery is challenged by the reservoir of bacteria that resides in hair follicles. Atmospheric pressure plasma jets (APPJs) have been proposed as a method to treat and deactivate these bacteria as atmospheric plasmas are able to penetrate into structures and crevices with dimensions similar to those found in hair follicles. In this paper, we discuss results from a computational investigation of an APPJ sustained in helium flowing into ambient air, and incident onto a layered dielectric similar to human skin in which there are idealized hair follicles. We found that, depending on the location of …