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Full-Text Articles in Medicine and Health Sciences

Decreased Recovery Time With Postoperative Pain Assessment In A Pacu, Eun Hey Gracie Yoon Sep 2023

Decreased Recovery Time With Postoperative Pain Assessment In A Pacu, Eun Hey Gracie Yoon

Master's Projects and Capstones

Abstract

PROBLEM: Improper postoperative pain assessment increased recovery time in the Post-Anesthesia Care Unit (PACU). Effective pain management is essential to improve the quality of patient care. Adequate pain control decreases readmissions and length of stay, which directly aligns with the institution’s priorities of providing high quality care at an affordable cost.

CONTEXT: ABC Hospital is a non-profit and community-focused regional medical center based in Pasadena, CA, with 5000 employees. It included 619-beds and became an affiliate of C Health System in August 2021. Improper postoperative pain management practices caused delayed length of stay and increased cost of care in …


Screening Patients For Physical Frailty In The Preoperative Phase, Sean V. Pottenger, Amanuel Gebeyehu Sep 2023

Screening Patients For Physical Frailty In The Preoperative Phase, Sean V. Pottenger, Amanuel Gebeyehu

Doctor of Nursing Practice (DNP) Student Projects

Background: Frailty is a syndrome characterized by an increased burden of symptoms and higher susceptibility to adverse health, including higher functional decline rates, pressure ulcers, falls, delirium, extended hospital stay, and discharge to assisted living facilities. Screening patients for frailty before undergoing a surgical procedure is recommended to minimize postoperative complications. In the preoperative phase at a midwestern academic hospital, surgical patients are not screened for frailty using a validated screening tool.

Purpose: This project sought to calculate the Clinical Frailty Scale (CFS) score using a novel algorithm. After validating the novel algorithm, this research project predicted that clinicians would …


Addressing Barriers To Anesthesia Clinicians Utilization Of The Perioperative Glycemic Management Guideline In Adult Surgical Patients With Diabetes At A Level 1 Midwestern Trauma Center, Neil Frydrych, Meghan Marshall Sep 2023

Addressing Barriers To Anesthesia Clinicians Utilization Of The Perioperative Glycemic Management Guideline In Adult Surgical Patients With Diabetes At A Level 1 Midwestern Trauma Center, Neil Frydrych, Meghan Marshall

Doctor of Nursing Practice (DNP) Student Projects

Background and Review of Literature: Diabetes Mellitus (DM) is a complex metabolic disorder characterized by hyperglycemia leading to adverse outcomes. There is an association between dysglycemia and adverse perioperative outcomes. Evidence-based research supports consistent blood glucose (BG) monitoring and narrow glycemic parameters for surgical patients in the perioperative setting. Implementing and adhering to a glycemic guideline can help improve patient outcomes and decrease hospital costs.

Purpose: This quality improvement project (QIP) aims to determine the barriers to anesthesia clinicians implementing the perioperative glycemic management guideline for BG levels greater than 180 mg/dL. Then, develop an educational component to increase anesthesia …


Associations Between Telomere Attrition, Genetic Variants In Telomere Maintenance Genes, And Non-Small Cell Lung Cancer Risk In The Jammu And Kashmir Population Of North India, Gh Rasool Bhat, Rajeshwer Singh Jamwal, Itty Sethi, Amrita Bhat, Ruchi Shah, Sonali Verma, Minerva Sharma, Hana Q Sadida, Sara K Al-Marzooqi, Tariq Masoodi, Sameer Mirza, Mohammad Haris, Muzafar A Macha, Ammira S Alshabeeb Akil, Ajaz A Bhat, Rakesh Kumar Sep 2023

Associations Between Telomere Attrition, Genetic Variants In Telomere Maintenance Genes, And Non-Small Cell Lung Cancer Risk In The Jammu And Kashmir Population Of North India, Gh Rasool Bhat, Rajeshwer Singh Jamwal, Itty Sethi, Amrita Bhat, Ruchi Shah, Sonali Verma, Minerva Sharma, Hana Q Sadida, Sara K Al-Marzooqi, Tariq Masoodi, Sameer Mirza, Mohammad Haris, Muzafar A Macha, Ammira S Alshabeeb Akil, Ajaz A Bhat, Rakesh Kumar

Faculty, Staff and Student Publications

BACKGROUND: Telomeres are repetitive DNA sequences located at the ends of chromosomes, playing a vital role in maintaining chromosomal integrity and stability. Dysregulation of telomeres has been implicated in the development of various cancers, including non-small cell lung cancer (NSCLC), which is the most common type of lung cancer. Genetic variations within telomere maintenance genes may influence the risk of developing NSCLC. The present study aimed to evaluate the genetic associations of select variants within telomere maintenance genes in a population from Jammu and Kashmir, North India, and to investigate the relationship between telomere length and NSCLC risk.

METHODS: We …


Narrative Review Of The Role Of Technology In Pediatric Diabetes: From Testing Blood Glucose To Subcutaneous Automated Therapy And Hope For Cure, Michael Yafi, Avni Shah, Katherine Velez Sep 2023

Narrative Review Of The Role Of Technology In Pediatric Diabetes: From Testing Blood Glucose To Subcutaneous Automated Therapy And Hope For Cure, Michael Yafi, Avni Shah, Katherine Velez

Faculty, Staff and Student Publications

BACKGROUND AND OBJECTIVE: Type 1 diabetes, the most common cause of diabetes in pediatrics, is defined by the hyperglycemia that results from the permanent autoimmune damage to the pancreas. The Diabetes Control and Complications Trial (DCCT) demonstrated that strict glycemic control targeting lower HbA1c goals can both delay the onset and progression of its complications that include diabetic neuropathy, nephropathy, retinopathy, and increased cardiovascular events. Our primary objective is to review the literature available regarding the technology applied for the treatment of diabetes, not only aiding patients' quality of life but addressing its effects on hypoglycemia and reduced risk of …


Age- And Sex-Specific Reference Values Of Biventricular Flow Components And Kinetic Energy By 4d Flow Cardiovascular Magnetic Resonance In Healthy Subjects, Xiaodan Zhao, Ru-San Tan, Pankaj Garg, Ping Chai, Shuang Leng, Jennifer Ann Bryant, Lynette L S Teo, Tee Joo Yeo, Marielle V Fortier, Ting Ting Low, Ching Ching Ong, Shuo Zhang, Rob J Van Der Geest, John C Allen, Teng Hong Tan, James W Yip, Ju Le Tan, Marina Hughes, Sven Plein, Jos J M Westenberg, Liang Zhong Sep 2023

Age- And Sex-Specific Reference Values Of Biventricular Flow Components And Kinetic Energy By 4d Flow Cardiovascular Magnetic Resonance In Healthy Subjects, Xiaodan Zhao, Ru-San Tan, Pankaj Garg, Ping Chai, Shuang Leng, Jennifer Ann Bryant, Lynette L S Teo, Tee Joo Yeo, Marielle V Fortier, Ting Ting Low, Ching Ching Ong, Shuo Zhang, Rob J Van Der Geest, John C Allen, Teng Hong Tan, James W Yip, Ju Le Tan, Marina Hughes, Sven Plein, Jos J M Westenberg, Liang Zhong

Faculty, Staff and Student Publications

BACKGROUND: Advances in four-dimensional flow cardiovascular magnetic resonance (4D flow CMR) have allowed quantification of left ventricular (LV) and right ventricular (RV) blood flow. We aimed to (1) investigate age and sex differences of 4D flow CMR-derived LV and RV relative flow components and kinetic energy (KE) parameters indexed to end-diastolic volume (KEi

METHODS: We performed 4D flow analysis in 163 healthy participants (42% female; mean age 43 ± 13 years) of a prospective registry study (NCT03217240) who were free of cardiovascular diseases. Relative flow components (direct flow, retained inflow, delayed ejection flow, residual volume) and multiple phasic KEi

RESULTS: …


Retraction Note: Mir20a/106a-Wtx Axis Regulates Rhogdia/Cdc42 Signaling And Colon Cancer Progression, Gui-Fang Zhu, Yang-Wei Xu, Jian Li, Hui-Lin Niu, Wen-Xia Ma, Jia Xu, Pei-Rong Zhou, Xia Liu, Dan-Li Ye, Xiao-Rong Liu, Tao Yan, Wei-Ke Zhai, Zhi-Jun Xu, Chun Liu, Lei Wang, Hao Wang, Jia-Mao Luo, Li Liu, Xuan-Qi Li, Suiqun Guo, Hui-Ping Jiang, Peng Shen, Hui-Kuan Lin, Di-Hua Yu, Yan-Qing Ding, Qing-Ling Zhang Sep 2023

Retraction Note: Mir20a/106a-Wtx Axis Regulates Rhogdia/Cdc42 Signaling And Colon Cancer Progression, Gui-Fang Zhu, Yang-Wei Xu, Jian Li, Hui-Lin Niu, Wen-Xia Ma, Jia Xu, Pei-Rong Zhou, Xia Liu, Dan-Li Ye, Xiao-Rong Liu, Tao Yan, Wei-Ke Zhai, Zhi-Jun Xu, Chun Liu, Lei Wang, Hao Wang, Jia-Mao Luo, Li Liu, Xuan-Qi Li, Suiqun Guo, Hui-Ping Jiang, Peng Shen, Hui-Kuan Lin, Di-Hua Yu, Yan-Qing Ding, Qing-Ling Zhang

Faculty, Staff and Student Publications

No abstract provided.


Intouch Week Of September 18, 2023, New York Medical College Sep 2023

Specific Polysaccharide Antibody Deficiency, Daniel M Musher Sep 2023

Specific Polysaccharide Antibody Deficiency, Daniel M Musher

Faculty, Staff and Students Publications

No abstract provided.


Lateral Approach To The Lumbar Spine: The Utility Of An Access Surgeon, Matthew Meade, Yunsoo Lee, Parker Brush, Mark Lambrechts, Eleanor Jenkins, Cristian Desimone, Michael Mccurdy, John Mangan, Jose Canseco, Mark Kurd, Alan Hilibrand, Alexander Vaccaro, Christopher Kepler, Gregory Schroeder Sep 2023

Lateral Approach To The Lumbar Spine: The Utility Of An Access Surgeon, Matthew Meade, Yunsoo Lee, Parker Brush, Mark Lambrechts, Eleanor Jenkins, Cristian Desimone, Michael Mccurdy, John Mangan, Jose Canseco, Mark Kurd, Alan Hilibrand, Alexander Vaccaro, Christopher Kepler, Gregory Schroeder

Department of Orthopaedic Surgery Faculty Papers

BACKGROUND: Lateral lumbar interbody fusions (LLIFs) utilize a retroperitoneal approach that avoids the intraperitoneal organs and manipulation of the anterior vasculature encountered in anterior approaches to the lumbar spine. The approach was championed by spinal surgeons; however, general/vasculature surgeons may be more comfortable with the approach.

OBJECTIVE: The objective of this study was to compare short-term outcomes following LLIF procedures based on whether a spine surgeon or access surgeon performed the approach.

MATERIALS AND METHODS: We retrospectively identified all one- to two-level LLIFs at a tertiary care center from 2011 to 2021 for degenerative spine disease. Patients were divided into …


Structural Features Of Thyroglobulin Linked To Protein Trafficking, Cintia E. Citterio, Kookjoo Kim, Bhavana Rajesh, Kevin Pena, Oliver Biggs Clark, Peter Arvan Sep 2023

Structural Features Of Thyroglobulin Linked To Protein Trafficking, Cintia E. Citterio, Kookjoo Kim, Bhavana Rajesh, Kevin Pena, Oliver Biggs Clark, Peter Arvan

Pharmacy Faculty Articles and Research

Thyroglobulin must pass endoplasmic reticulum (ER) quality control to become secreted for thyroid hormone synthesis. Defective thyroglobulin, blocked in trafficking, can cause hypothyroidism. Thyroglobulin is a large protein (~2750 residues) spanning regions I–II–III plus a C-terminal cholinesterase-like domain. The cholinesterase-like domain functions as an intramolecular chaperone for regions I–II–III, but the folding pathway leading to successful thyroglobulin trafficking remains largely unknown. Here, informed by the recent three-dimensional structure of thyroglobulin as determined by cryo-electron microscopy, we have bioengineered three novel classes of mutants yielding three entirely distinct quality control phenotypes. Specifically, upon expressing recombinant thyroglobulin, we find that first, mutations …


The Missed And The Misdiagnosed: Geriatric Delirium In The Emergency Department, Christienne Shams, Yashar Eshman, Ronan Factora, Stephen Meldon, Saket Saxena Sep 2023

The Missed And The Misdiagnosed: Geriatric Delirium In The Emergency Department, Christienne Shams, Yashar Eshman, Ronan Factora, Stephen Meldon, Saket Saxena

Journal of Geriatric Emergency Medicine

Background: Older patients with delirium are at increased risk for prolonged hospitalization, poor outcomes, higher costs and a greater risk for institutionalization. By identifying those at risk early, interventions can be implemented to prevent or minimize the severity of the delirium. Per hospital policy, our geriatric emergency department (ED) screens for delirium by performing a 4AT only if changes in mental status are noted by caregivers or healthcare providers familiar with the patient. We hypothesize this approach underestimates the prevalence of delirium on presentation to the ED, particularly among high-risk older patients. The aim of this study is to determine …


Bilateral Severe Iatrogenic Pigmentary Glaucoma Following Laser Treatment For Cosmetic Iris Color Change, Jiaru Liu, Salim Korban, Marlene R. Moster, Marc-André Rhéaume, Qianqian Wang Sep 2023

Bilateral Severe Iatrogenic Pigmentary Glaucoma Following Laser Treatment For Cosmetic Iris Color Change, Jiaru Liu, Salim Korban, Marlene R. Moster, Marc-André Rhéaume, Qianqian Wang

Wills Eye Hospital Papers

PURPOSE: We report a case of bilateral severe pigmentary glaucoma and paracentral acute middle maculopathy (PAMM) following laser treatment for iris color change.

OBSERVATIONS: A 32-year-old female presented to our emergency clinic after having undergone 4 sessions of bilateral cosmetic iris laser treatment in Turkey to lighten the color of her dark brown irides. Visual acuity was 20/150 in the right eye (OD) and counting fingers in the left eye (OS) at presentation. Intraocular pressures (IOP) were 50 mmHg in the right eye and 42 mmHg in the left eye, with 4+ free-floating pigmented cells in the anterior chamber. The …


Neuroimmune Support Of Neuronal Regeneration And Neuroplasticity Following Cerebral Ischemia In Juvenile Mice, Ricaurte A Marquez-Ortiz, Vesna Tesic, Daniel R Hernandez, Bilkis Akhter, Nibedita Aich, Porter M Boudreaux, Garrett A Clemons, Celeste Yin-Chieh Wu, Hung Wen Lin, Krista M Rodgers Sep 2023

Neuroimmune Support Of Neuronal Regeneration And Neuroplasticity Following Cerebral Ischemia In Juvenile Mice, Ricaurte A Marquez-Ortiz, Vesna Tesic, Daniel R Hernandez, Bilkis Akhter, Nibedita Aich, Porter M Boudreaux, Garrett A Clemons, Celeste Yin-Chieh Wu, Hung Wen Lin, Krista M Rodgers

Faculty, Staff and Student Publications

Ischemic damage to the brain and loss of neurons contribute to functional disabilities in many stroke survivors. Recovery of neuroplasticity is critical to restoration of function and improved quality of life. Stroke and neurological deficits occur in both adults and children, and yet it is well documented that the developing brain has remarkable plasticity which promotes increased post-ischemic functional recovery compared with adults. However, the mechanisms underlying post-stroke recovery in the young brain have not been fully explored. We observed opposing responses to experimental cerebral ischemia in juvenile and adult mice, with substantial neural regeneration and enhanced neuroplasticity detected in …


A Bifid Attachment Of Latissimus Dorsi To Humerus Enclosing Neuro-Vascular Structures: A Case Report, Yaajnavalkya Hebbar K, Rashmi Bhat, Lalu Krishna Kn Sep 2023

A Bifid Attachment Of Latissimus Dorsi To Humerus Enclosing Neuro-Vascular Structures: A Case Report, Yaajnavalkya Hebbar K, Rashmi Bhat, Lalu Krishna Kn

KCACON 2023

No abstract provided.


Caval Variants - Imaging Spectrum In Superior And Inferior Venacava, Shyamala B Y, Nishaa P, Padmalatha K Sep 2023

Caval Variants - Imaging Spectrum In Superior And Inferior Venacava, Shyamala B Y, Nishaa P, Padmalatha K

KCACON 2023

No abstract provided.


Bilateral Presence Of An Accessory Tendon Of The Flexor Hallucis Longus And The Accessory Flexor Digitorum Longus: A Case Report, Krish Bhambhani, Khushi Shah, Sheetal V Pattanshetti, Shilpa M Bhimalli Sep 2023

Bilateral Presence Of An Accessory Tendon Of The Flexor Hallucis Longus And The Accessory Flexor Digitorum Longus: A Case Report, Krish Bhambhani, Khushi Shah, Sheetal V Pattanshetti, Shilpa M Bhimalli

KCACON 2023

No abstract provided.


Volvulus Of The Meckels Diverticulum: Untying Of The Mystery Knot!, Arpita Navarasu, Nishaa P, Padmalatha K Sep 2023

Volvulus Of The Meckels Diverticulum: Untying Of The Mystery Knot!, Arpita Navarasu, Nishaa P, Padmalatha K

KCACON 2023

No abstract provided.


The Study Of Morphology And Morphometric Parameters Of Greater Sciatic Notch In Dry Hip Bones, Olivia Mary John, Hema N, Shivapriya ., Seema R Sep 2023

The Study Of Morphology And Morphometric Parameters Of Greater Sciatic Notch In Dry Hip Bones, Olivia Mary John, Hema N, Shivapriya ., Seema R

KCACON 2023

No abstract provided.


Morphometric Analysis Of Floor Of Fourth Ventricle In Cadaveric Brain Specimens, Sristi Chakraborty, Arvind Kumar Pandey Sep 2023

Morphometric Analysis Of Floor Of Fourth Ventricle In Cadaveric Brain Specimens, Sristi Chakraborty, Arvind Kumar Pandey

KCACON 2023

No abstract provided.


An Unusual Branch Of Axillary Artery Communicating With Radial Artery: A Case Report, Sonal Nayak, Roshni Sadashiv, Aamna Kausar, Sharanya Rao, Veena Kulkarni Sep 2023

An Unusual Branch Of Axillary Artery Communicating With Radial Artery: A Case Report, Sonal Nayak, Roshni Sadashiv, Aamna Kausar, Sharanya Rao, Veena Kulkarni

KCACON 2023

No abstract provided.


Horseshoe Kidney: A Fusion Anomaly, Pranav Reddy L, Geethanjali B S, Chandana Udayakumar, Martin Lucas A Sep 2023

Horseshoe Kidney: A Fusion Anomaly, Pranav Reddy L, Geethanjali B S, Chandana Udayakumar, Martin Lucas A

KCACON 2023

No abstract provided.


Anatomical Variation In Branching Pattern Of Subclavian Artery – A Cadaveric Study, P Manu Pradhaan, Vasudha T K Sep 2023

Anatomical Variation In Branching Pattern Of Subclavian Artery – A Cadaveric Study, P Manu Pradhaan, Vasudha T K

KCACON 2023

No abstract provided.


Anatomical Variation In The Formation Of Median Nerve And Its Communication With The Musculocutaneous Nerve In The Axilla: A Case Report, Nikhil S, Vanitha Naik, Rashmi Bhat, Gajanand Pujari Sep 2023

Anatomical Variation In The Formation Of Median Nerve And Its Communication With The Musculocutaneous Nerve In The Axilla: A Case Report, Nikhil S, Vanitha Naik, Rashmi Bhat, Gajanand Pujari

KCACON 2023

No abstract provided.


A Case Report On Situs Inversus Totalis, Manya Dhari, Vasudha Kulkarni Sep 2023

A Case Report On Situs Inversus Totalis, Manya Dhari, Vasudha Kulkarni

KCACON 2023

No abstract provided.


Thyroglossal Duct Cyst: A Case Presentation, Maanasi Srinivas, Geethanjali Bs, Niveditha ., Martin Lucas Sep 2023

Thyroglossal Duct Cyst: A Case Presentation, Maanasi Srinivas, Geethanjali Bs, Niveditha ., Martin Lucas

KCACON 2023

No abstract provided.


Assessment And Analysis Of Human Laterality For Manipulation And Communication Gestures Using Renne’S Laterality Questionnaire., Leya H M, Vasudha Kulkarni Sep 2023

Assessment And Analysis Of Human Laterality For Manipulation And Communication Gestures Using Renne’S Laterality Questionnaire., Leya H M, Vasudha Kulkarni

KCACON 2023

No abstract provided.


A Case Report On Tricipital Tendon Of Biceps Brachii Muscle, Harsh Raj, Suganitha Balasundaram, Vasudha Kulkarni Sep 2023

A Case Report On Tricipital Tendon Of Biceps Brachii Muscle, Harsh Raj, Suganitha Balasundaram, Vasudha Kulkarni

KCACON 2023

No abstract provided.


Transposition Of Great Arteries, Bilva Teja, Padmalatha ., Nishaa . Sep 2023

Transposition Of Great Arteries, Bilva Teja, Padmalatha ., Nishaa .

KCACON 2023

No abstract provided.


Cross Sectional Study On Normal Parameters Of Cruciate Ligaments Of Adult Knee Joints Using Mri Scan., Varsha Shenoy, Ram Shenoy Sep 2023

Cross Sectional Study On Normal Parameters Of Cruciate Ligaments Of Adult Knee Joints Using Mri Scan., Varsha Shenoy, Ram Shenoy

KCACON 2023

No abstract provided.