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Articles 6601 - 6630 of 324930

Full-Text Articles in Medicine and Health Sciences

Colo-Ovarian Fistula Presenting As Tubo-Ovarian Abscess, Jessica Harper, Michelle Mieles, Kyle Biggs Apr 2026

Colo-Ovarian Fistula Presenting As Tubo-Ovarian Abscess, Jessica Harper, Michelle Mieles, Kyle Biggs

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Reducing Surgical Site Infection After Colorectal Surgery: A Multidisciplinary Review Of Process Improvement, Robin Daemmrich, Quentin Dipasquale, Deborah Klepac, Nick Mathers, Travis Holloway Apr 2026

Reducing Surgical Site Infection After Colorectal Surgery: A Multidisciplinary Review Of Process Improvement, Robin Daemmrich, Quentin Dipasquale, Deborah Klepac, Nick Mathers, Travis Holloway

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Ai-Enhanced Preparation For Emigs Cognitive Exam, Anjali Patel, Fatima Hussain, Jennifer Dulaney, Linda Haddox Apr 2026

Ai-Enhanced Preparation For Emigs Cognitive Exam, Anjali Patel, Fatima Hussain, Jennifer Dulaney, Linda Haddox

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


A Model For Creating Ai-Generated Simulations For Clinically Complex Scenarios, Makayla Morning, Parker Litchliter, Jennifer Dulaney, Linda Haddox Apr 2026

A Model For Creating Ai-Generated Simulations For Clinically Complex Scenarios, Makayla Morning, Parker Litchliter, Jennifer Dulaney, Linda Haddox

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Views, Knowledge, And Implications Of Abortion Law In Texas Obgyn Residencies, Jessica Harper, Sharon Barazani, Kate Mowry, Melissa Mendez Apr 2026

Views, Knowledge, And Implications Of Abortion Law In Texas Obgyn Residencies, Jessica Harper, Sharon Barazani, Kate Mowry, Melissa Mendez

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


An Unusual Brain Invader: A Case Of Adult Viral Meningitis, Gregory Williams, Jonathan Barnett Apr 2026

An Unusual Brain Invader: A Case Of Adult Viral Meningitis, Gregory Williams, Jonathan Barnett

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Catheter Directed Thrombolysis And Aspiration Thrombectomy In Patients Treated For Pulmonary Embolisms: In-Hospital Outcomes, Amelia Mellor, Daniel Ortiz, Suzanne Perkins Apr 2026

Catheter Directed Thrombolysis And Aspiration Thrombectomy In Patients Treated For Pulmonary Embolisms: In-Hospital Outcomes, Amelia Mellor, Daniel Ortiz, Suzanne Perkins

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Mycobacterial Soft Tissue Infection Following Gluteal Fat Grafting: A Case Report And Review Of Surgical Asepsis Implications, Sophia Ahmed, Chandra Ellis Apr 2026

Mycobacterial Soft Tissue Infection Following Gluteal Fat Grafting: A Case Report And Review Of Surgical Asepsis Implications, Sophia Ahmed, Chandra Ellis

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Progressive Neuropathy With Normal Vitamin B12 Levels And Demyelinating Findings, Michael Rollins, Juan Rodriguez, Laura Preece Apr 2026

Progressive Neuropathy With Normal Vitamin B12 Levels And Demyelinating Findings, Michael Rollins, Juan Rodriguez, Laura Preece

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Diagnostic Challenges And Surgical Management Of A Cervical Ectopic Pregnancy Mimicking Cesarean Scar Implantation, Xena Morataya, Laura Reguero, Uti Essien, Stacy Sassaman, Jorge Venegas Apr 2026

Diagnostic Challenges And Surgical Management Of A Cervical Ectopic Pregnancy Mimicking Cesarean Scar Implantation, Xena Morataya, Laura Reguero, Uti Essien, Stacy Sassaman, Jorge Venegas

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Are You My Doctor? Impact Of Role Identification Badges In Improving Resident Experience, Rasmeet Kaur, Laura Preece Apr 2026

Are You My Doctor? Impact Of Role Identification Badges In Improving Resident Experience, Rasmeet Kaur, Laura Preece

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


An Unlikely Killer: Iatrogenic Botulism And Respiratory Paralysis As A Result Of Botched Botox Injection, Gregory Williams, Anabel Al Abdallah, Jonathan Barnett Apr 2026

An Unlikely Killer: Iatrogenic Botulism And Respiratory Paralysis As A Result Of Botched Botox Injection, Gregory Williams, Anabel Al Abdallah, Jonathan Barnett

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Symptomatic Chiari 1 Malformation In A 35-Year-Old Female, Ignatius Mmodebelu, Jaime Natividad, Jonathan Carpenter, Juan Rodriguez Apr 2026

Symptomatic Chiari 1 Malformation In A 35-Year-Old Female, Ignatius Mmodebelu, Jaime Natividad, Jonathan Carpenter, Juan Rodriguez

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Recurrent Molar Pregnancy – A Case Report, Jayce Jaynes, Sarina Garcia, Dorovenia Hawkins-Koch Apr 2026

Recurrent Molar Pregnancy – A Case Report, Jayce Jaynes, Sarina Garcia, Dorovenia Hawkins-Koch

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


A Rare Case Of Disseminated Herpes Zoster, Reza Nasrollahzadeh, Andrea Francis, Rasmeet Kaur, Micheline Tantchou Apr 2026

A Rare Case Of Disseminated Herpes Zoster, Reza Nasrollahzadeh, Andrea Francis, Rasmeet Kaur, Micheline Tantchou

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


A Unique Case Of Tumor Thrombus In The Superior Vena Cava (Svc), John Leece, Juan Rodriguez Apr 2026

A Unique Case Of Tumor Thrombus In The Superior Vena Cava (Svc), John Leece, Juan Rodriguez

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.


Clinical Applications Of Topical Platelet-Rich Plasma In Cardiac Surgery: A Scoping Review, Jaron M. Davis Apr 2026

Clinical Applications Of Topical Platelet-Rich Plasma In Cardiac Surgery: A Scoping Review, Jaron M. Davis

Student Works

Background: Postoperative wound complications persist as a significant challenge within adult cardiac surgery. Deep and superficial sternal wound infections, along with complications at saphenous vein harvest sites, are linked to increased morbidity, extended hospital stays, and substantial healthcare expenses. Topical platelet-rich plasma (PRP), commonly known as platelet gel, has been suggested as a biologically active adjunct that may facilitate tissue repair and mitigate postoperative complications. While PRP has garnered attention in surgical practice, the overall scope and consistency of the supporting evidence in cardiac surgery remain ambiguous.

Objective: The purpose of this scoping review is to map and describe the …


Safety And Efficacy Of Ciltacabtagene Autoleucel For Relapsed/Refractory Multiple Myeloma: A Cibmtr Study., Doris K Hansen, Danai Dima, Hira Mian, Jakob Devos, Ruta Brazauskas, Temitope Oloyede, Aimaz Afrough, Nausheen Ahmed, Larry Anderson, Rahul Banerjee, Jesus G Berdeja, Aram Bidikian, Binod Dhakal, Ajoy Dias, Yvonne Efebera, Muhammad Salman Faisal, Lohith Gowda, Hamza Hashmi, Abu-Sayeef Mirza, Meera Mohan, Ravi Narra, Ashley E Rosko, Mark Schroeder, Taiga Nishihori, Heather Landau, Saad Usmani, Marcelo C Pasquini, Othman S Akhtar, Surbhi Sidana, Krina K Patel Apr 2026

Safety And Efficacy Of Ciltacabtagene Autoleucel For Relapsed/Refractory Multiple Myeloma: A Cibmtr Study., Doris K Hansen, Danai Dima, Hira Mian, Jakob Devos, Ruta Brazauskas, Temitope Oloyede, Aimaz Afrough, Nausheen Ahmed, Larry Anderson, Rahul Banerjee, Jesus G Berdeja, Aram Bidikian, Binod Dhakal, Ajoy Dias, Yvonne Efebera, Muhammad Salman Faisal, Lohith Gowda, Hamza Hashmi, Abu-Sayeef Mirza, Meera Mohan, Ravi Narra, Ashley E Rosko, Mark Schroeder, Taiga Nishihori, Heather Landau, Saad Usmani, Marcelo C Pasquini, Othman S Akhtar, Surbhi Sidana, Krina K Patel

Oncology Articles

Ciltacabtagene autoleucel (cilta-cel), an anti-B-cell maturation antigen (BCMA) chimeric antigen receptor T-cell (CAR-T) therapy, was approved in 2022 for heavily pretreated relapsed/refractory multiple myeloma (RRMM). This study evaluates the safety and efficacy of cilta-cel in RRMM patients reported to the Center for International Blood and Marrow Transplant Research registry between March 2022 and December 2023 who met commercial release specifications. Among 595 patients, median age was 64 years, 57% were male, and 70% had ≥1 comorbidity. Extramedullary disease and marrow plasma cell burden ≥ 50% were present in 13% and 14% of patients, respectively. The median number of prior lines …


Effects Of Colchicine On Sah-Induced Vascular Damage In An Experimental Subarachnoid Hemorrhage Model ​, Emi̇ne Demi̇r, Cumaali̇ Demi̇rtaş, Cansu Sönmez, Eray Meti̇n Güler, Sarper Kocaoğlu, Hakan Beyaztaş, Eyüp Çeti̇n Apr 2026

Effects Of Colchicine On Sah-Induced Vascular Damage In An Experimental Subarachnoid Hemorrhage Model ​, Emi̇ne Demi̇r, Cumaali̇ Demi̇rtaş, Cansu Sönmez, Eray Meti̇n Güler, Sarper Kocaoğlu, Hakan Beyaztaş, Eyüp Çeti̇n

Turkish Journal of Medical Sciences

Background/aim: Subarachnoid hemorrhage (SAH) is a severe cerebrovascular condition associated with high morbidity and mortality. Inflammation and oxidative stress play critical roles in its pathophysiology, especially in the development of secondary vascular damage. This study aimed to evaluate the protective effects of colchicine on vascular integrity and biochemical markers following SAH in an experimental rat model.

Materials and methods: Eighteen female Sprague Dawley rats were randomly divided into 3 groups: Control (no SAH), SAH (induced without treatment), and SAH + colchicine (received intraperitoneal colchicine at a dose of 1 mg/kg). SAH was induced by injecting autologous blood into the cisterna …


From Beauty To Burden: Mapping The Health And Psychosocial Impacts Of Fragrances And Cosmetic Products Use In The Uae, Sharifa Alblooshi, Mariam Al Ali, Dana N. Abdelrahim, Suheir Awadalla Apr 2026

From Beauty To Burden: Mapping The Health And Psychosocial Impacts Of Fragrances And Cosmetic Products Use In The Uae, Sharifa Alblooshi, Mariam Al Ali, Dana N. Abdelrahim, Suheir Awadalla

All Works

Background The dynamic beauty care sector in the Middle East is on an upward trend in the UAE; however, concerns persist about the side effects of this industry, attributed to chemical exposure, which is believed to contribute to skin problems and other health issues. In the UAE, there is a lack of data on consumer usage, awareness, and the health effects associated with it.Methods This study presents the results of an online survey administered to 461 female subjects in the United Arab Emirates as part of a cross-sectional study. The survey consisted of 55 questions on product use, knowledge, attitudes, …


Tremor Modulation: A Systematic Review Of Resetting By Single-Pulse Transcranial Magnetic Stimulation ​, Handan Uzunçakmak Uyanik, Çağri Mesut Temuçi̇n Apr 2026

Tremor Modulation: A Systematic Review Of Resetting By Single-Pulse Transcranial Magnetic Stimulation ​, Handan Uzunçakmak Uyanik, Çağri Mesut Temuçi̇n

Turkish Journal of Medical Sciences

Background/aim: Tremor arises from mechanical, reflex, or central oscillatory mechanisms. Transcranial magnetic stimulation (TMS) can transiently perturb ongoing tremor and enables the quantitative assessment of phase resetting, offering circuit-level insight into tremor types. Although numerous studies have applied TMS-induced resetting, the findings have not been systematically reviewed. This study systematically reviews human studies evaluating TMS-induced tremor resetting across tremor types.

Materials and methods: A systematic search of PubMed and Google Scholar identified human studies using TMS to perturb tremor or rhythmic movement. Search terms included “tremor resetting,” “resetting of tremor,” “tremor phase shift,” “tremor phase reset,” “transcranial magnetic stimulation,” and …


Artificial Intelligence-Assisted Neuropharmacology: Reshaping Drug Discovery And Translational Strategies For Neurological Diseases ​, Pri̇yanka Rathee, Suni̇thi̇ Lohan, Sari̇ta Khatkar, Neelam Mali̇k, Esra Akkol, Renu Sehrawat, Pooja Rathee, Anurag Khatkar Apr 2026

Artificial Intelligence-Assisted Neuropharmacology: Reshaping Drug Discovery And Translational Strategies For Neurological Diseases ​, Pri̇yanka Rathee, Suni̇thi̇ Lohan, Sari̇ta Khatkar, Neelam Mali̇k, Esra Akkol, Renu Sehrawat, Pooja Rathee, Anurag Khatkar

Turkish Journal of Medical Sciences

The rapid expansion of data-driven technologies, particularly machine learning (ML) and artificial intelligence (AI), has substantially influenced biomedical research and drug discovery. In neuropharmacology, the availability of large-scale genomic, proteomic, chemical, and clinical datasets has stimulated the adoption of AI-based approaches to address persistent challenges in neurological drug development, including high attrition rates and the scarcity of disease-modifying therapies. Unlike prior reviews that broadly discuss AI applications in drug discovery or neurology, this narrative review focuses specifically on neuropharmacology, with an emphasis on translational relevance, disease-oriented examples, and real-world constraints. We critically examine the application of AI and ML across …


Comparative Efficacy Of Repetitive Peripheral Magnetic Stimulation And Transcutaneous Electrical Nerve Stimulation In Upper Trapezius Myofascial Pain Syndrome ​, Shahri̇yar Kalbi̇yev, Şehi̇m Kutlay, Ati̇lla Hali̇l Elhan, Yeşi̇m Kurtai̇ş Aytür, Aysun Genç Apr 2026

Comparative Efficacy Of Repetitive Peripheral Magnetic Stimulation And Transcutaneous Electrical Nerve Stimulation In Upper Trapezius Myofascial Pain Syndrome ​, Shahri̇yar Kalbi̇yev, Şehi̇m Kutlay, Ati̇lla Hali̇l Elhan, Yeşi̇m Kurtai̇ş Aytür, Aysun Genç

Turkish Journal of Medical Sciences

Background/aim: In this prospective, randomized, single-blind study, the effects of repetitive peripheral magnetic stimulation (rPMS) and transcutaneous electrical nerve stimulation (TENS) on pain intensity, functional status, and tissue elasticity were evaluated in patients with upper trapezius myofascial pain syndrome (MPS).

Materials and methods: A total of 75 female patients were randomly allocated to three groups: rPMS, TENS, and sham rPMS. All participants were provided with an exercise program consisting of cervical range-of-motion (ROM), stretching, and strengthening exercises. Outcome measures included pain intensity assessed using the visual analog scale, pressure pain threshold (PPT), the Neck Disability Index, cervical ROM, SF-36 subscale …


Res-Mnd: Motor Neuron Disease Detection Using Res4net–Convolutional Block Attention Module ​, Shuriya Balusamy, Rakesh Sivalingam, Shobana Rooben, Sony Helen Apr 2026

Res-Mnd: Motor Neuron Disease Detection Using Res4net–Convolutional Block Attention Module ​, Shuriya Balusamy, Rakesh Sivalingam, Shobana Rooben, Sony Helen

Turkish Journal of Medical Sciences

Background/aim: Motor neuron diseases (MNDs) are progressive neurological disorders that cause muscle weakness and wasting as a result of ongoing neurodegeneration. MNDs require comprehensive diagnostic approaches that integrate clinical symptoms, laboratory findings, and multimodal imaging data.

Materials and methods: In this study, a novel residual network for motor neuron disease detection (RES-MND) framework is proposed for detecting MNDs using multimodal imaging data. Initially, the input multimodal images, including MRI, CT, PET, and DTI, are preprocessed using adaptive dynamic histogram equalization and the total variation bilateral filter. The preprocessed multimodal images are processed through Res4Net-CBAM for feature extraction to enhance image …


Role Of Novel Renal Biomarkers In Prognosticating Patients With Chronic Kidney Disease: A Prospective Cohort Study, Raghavan Padmanabhan, Kaviya Manoharan, Melina Sahay, Pooja Bhujangarao, Luxitaa Goenka, Solai Priya, Kumaraswamy Subramaniyan, Damal Kandadai Sriram, Melvin George Apr 2026

Role Of Novel Renal Biomarkers In Prognosticating Patients With Chronic Kidney Disease: A Prospective Cohort Study, Raghavan Padmanabhan, Kaviya Manoharan, Melina Sahay, Pooja Bhujangarao, Luxitaa Goenka, Solai Priya, Kumaraswamy Subramaniyan, Damal Kandadai Sriram, Melvin George

Turkish Journal of Medical Sciences

Background/aim: Several biomarkers have been assessed for the diagnosis of chronic kidney disease (CKD). However, limited data are available regarding their ability to predict mortality in CKD. The aim of this study was to assess the ability of lipocalin-2, receptor for advanced glycation end products (RAGE), tissue inhibitor of metalloproteinase 1 (TIMP-1), osteopontin, and trefoil factor 3 (TFF-3) in predicting the prognosis of patients with CKD.

Materials and methods: We included patients with CKD as defined by an estimated glomerular filtration rate of <60 mL/min/1.73 m2 of either sex who were above the age of 18 years. Patients with a history of acute-on-chronic kidney disease were excluded. The novel markers of interest were estimated from patients’ plasma samples using the multiplex enzyme-linked immunosorbent assay. These patients were followed for 1 year to assess mortality.

Results: The median (with interquartile range) plasma concentrations of lipocalin-2, RAGE, TIMP-1, osteopontin, and TFF-3 were 56.9 …


The Importance Of Early Intraoperative Ultrasonography And The Relationship Between Surgical Technique And Allograft Function In Patients With Compartment Syndrome Following Renal Transplantation Surgery ​, Burak Yağdiran, Emre Karakaya, Ravana Ahmadli̇, Adem Şafak, Yağmur Kurtuluş, Nedi̇m Çekmen, Meri̇ç Yavuz Çolak, Mehmet Haberal Apr 2026

The Importance Of Early Intraoperative Ultrasonography And The Relationship Between Surgical Technique And Allograft Function In Patients With Compartment Syndrome Following Renal Transplantation Surgery ​, Burak Yağdiran, Emre Karakaya, Ravana Ahmadli̇, Adem Şafak, Yağmur Kurtuluş, Nedi̇m Çekmen, Meri̇ç Yavuz Çolak, Mehmet Haberal

Turkish Journal of Medical Sciences

Background/aim: In rare cases, patients undergoing renal transplantation (RT) may develop renal allograft compartment syndrome (RACS) if the renal volume is larger than the retroperitoneal space prepared in the iliac fossa. In such cases, the optimal treatment is early decompression surgery. The primary aim of the present descriptive and comparative study is not to identify the optimal surgical technique, but rather to evaluate the role of early Doppler ultrasonography (DUSG) in the recognition of renal allograft compartment syndrome and to assess outcomes following timely decompressive interventions.

Materials and methods: A total of 275 patients were examined retrospectively for the study, …


Impact Of Two Sedation Protocols On Cardiac Electrophysiology During Spinal Anesthesia ​, Selvi̇naz Durantaş, Burak Nalbant, Fatma Kavak Akelma, Gökhan Erdem, Abdulkadi̇r But Apr 2026

Impact Of Two Sedation Protocols On Cardiac Electrophysiology During Spinal Anesthesia ​, Selvi̇naz Durantaş, Burak Nalbant, Fatma Kavak Akelma, Gökhan Erdem, Abdulkadi̇r But

Turkish Journal of Medical Sciences

Background/aim: Perioperative factors such as anesthetic drugs, central blocks, surgical stress, pain, and anxiety can affect cardiac electrophysiology and increase the risk of arrhythmias. Arrhythmia susceptibility can be assessed using ventricular markers such as the QT interval (QT), heart rate-corrected QT interval (QTc), QT dispersion (QTd), time between peak and end of T wave (Tp–e), cardiac electrophysiologic balance index (iCEB), and heart rate-corrected index of cardiac electrophysiologic balance (iCEBc), obtained from noninvasive electrocardiography (ECG) data. This study compared the effects of propofol and dexmedetomidine sedation on these parameters in patients undergoing total knee arthroplasty performed under spinal anesthesia.

Materials and …


Analysis Of Calr-Mutated Essential Thrombocythemia As A Distinct Disease Entity Compared With Jak2 V617f-Mutated And Triple-Negative Patients ​, Gökhan Sami̇ Aydin, Eli̇f Aksoy, İpek Yönal Hi̇ndi̇lerden, Aynur Dağlar Aday, Emi̇ne Gültürk, Meli̇ha Nalçaci, Fehmi̇ Hi̇ndi̇lerden Apr 2026

Analysis Of Calr-Mutated Essential Thrombocythemia As A Distinct Disease Entity Compared With Jak2 V617f-Mutated And Triple-Negative Patients ​, Gökhan Sami̇ Aydin, Eli̇f Aksoy, İpek Yönal Hi̇ndi̇lerden, Aynur Dağlar Aday, Emi̇ne Gültürk, Meli̇ha Nalçaci, Fehmi̇ Hi̇ndi̇lerden

Turkish Journal of Medical Sciences

Background/aim: Calreticulin (CALR) mutations in essential thrombocythemia (ET) are associated with younger age, higher platelet counts, and lower thrombosis rates. The present study analyzes the demographic, laboratory, and clinical features of the CALR mutation and its prognostic impact.

Materials and methods: The clinical impact of CALR mutations was assessed in 391 ET patients.

Results: CALR-mutation patients were more commonly male than JAK2 V617F-positive and triple-negative patients. Age at diagnosis was similar across all groups, although patients with type 2 CALR mutations were younger than those with nontype 1/nontype 2 mutations. Compared with JAK2 V617F-positive patients, CALR-mutation patients had lower leukocyte …


Asthma Data In Türkiye Between 2016 And 2022: A Nationwide Descriptive And Observational Study Covering The Entire Adult Population, Kurtuluş Aksu, Gürgün Tuğçe Vural Solak, Nai̇m Ata, Mustafa Hami̇dullah Türkkani, Mustafa Mahi̇r Ülgü, Şuayi̇p Bi̇ri̇nci̇, Funda Aksu Apr 2026

Asthma Data In Türkiye Between 2016 And 2022: A Nationwide Descriptive And Observational Study Covering The Entire Adult Population, Kurtuluş Aksu, Gürgün Tuğçe Vural Solak, Nai̇m Ata, Mustafa Hami̇dullah Türkkani, Mustafa Mahi̇r Ülgü, Şuayi̇p Bi̇ri̇nci̇, Funda Aksu

Turkish Journal of Medical Sciences

Background/aim: Determining the current burden of asthma in countries is important in the diagnosis and follow-up of asthma patients and for the development of national health policies. Our study aimed to clarify the epidemiological and clinical data regarding asthmatic adults in Türkiye.

Materials and methods: The study was designed as a nationwide descriptive, observational cross-sectional study. Data on adult patients who were followed with the diagnosis of asthma in all public, private, and university hospitals in Türkiye between January 2016 and December 2022 were obtained from the e-Nabız database of the Ministry of Health and analyzed.

Results: The number of …


Comprehensive Profiling Of Gut Microbiota In Postmenopausal Osteoporosis ​, Gülsemi̇n Ertürk Çeli̇k, Sedat Yildiz, Münevver Aksoy Bektaş, Yaprak Engi̇n-Üstün Apr 2026

Comprehensive Profiling Of Gut Microbiota In Postmenopausal Osteoporosis ​, Gülsemi̇n Ertürk Çeli̇k, Sedat Yildiz, Münevver Aksoy Bektaş, Yaprak Engi̇n-Üstün

Turkish Journal of Medical Sciences

Background/aim: Osteoporosis is a multifactorial skeletal disease that predominantly affects postmenopausal women and is characterized by reduced bone mass and an increased risk of fractures. Growing evidence suggests that the gut microbiota plays a pivotal role in bone metabolism through immunological, endocrine, and metabolic pathways, forming the basis of the so-called gut– bone axis. This study aimed to characterize gut microbiota composition in postmenopausal women with osteoporosis compared with healthy controls.

Materials and methods: Forty postmenopausal women aged 55–65 years were classified into osteoporosis (n = 20) and healthy control (n = 20) groups based on dual-energy X-ray absorptiometry T-scores. …