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Articles 64981 - 65010 of 325722

Full-Text Articles in Medicine and Health Sciences

Journal Of The Arkansas Academy Of Science Volume 78, Academy Editors Jan 2024

Journal Of The Arkansas Academy Of Science Volume 78, Academy Editors

Journal of the Arkansas Academy of Science

No abstract provided.

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New Treatment Modality For Metastatic Cancer By Targeting The Endothelin Type A Receptor (Etar), Elbara Fathelrahman Abdelmoula Jan 2024

New Treatment Modality For Metastatic Cancer By Targeting The Endothelin Type A Receptor (Etar), Elbara Fathelrahman Abdelmoula

Theses

Ambrisentan, an FDA-approved selective antagonist of the Endothelin Type A Receptor (ETAR) for pulmonary arterial hypertension, has shown potential in limiting cancer growth and metastasis. While effective treatment options for melanoma remain elusive, this study investigates the effects of Ambrisentan on invasive, metastatic B16F10 melanoma using a syngeneic mouse model, aiming to assess Ambrisentan’s impact on tumor growth, metastasis, and overall host survival in B16F10 melanoma, along with gaining mechanistic insights into ETAR antagonism. C57Bl/6 mice were divided into two groups, receiving either dH2O or Ambrisentan orally. Treatments commenced prior to tumor implantation and continued post-implantation. Luciferase-expressing B16F10 cells facilitated …

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Neuromuscular Adaptations To Different Set Configurations During A Periodized Power Training Block In Elite Junior Judokas, Dale M. Harris, Dustin J. Oranchuk, Christopher Latella Jan 2024

Neuromuscular Adaptations To Different Set Configurations During A Periodized Power Training Block In Elite Junior Judokas, Dale M. Harris, Dustin J. Oranchuk, Christopher Latella

Research outputs 2022 to 2026

Although the impacts of traditional sets (TS) versus cluster (CL) sets resistance training have been broadly explored among recreationally trained populations, no studies have previously compared these set configurations among elite Judokas. Twenty-two elite male and female Judokas (age = 17.5 ± 1.2 years) performed identical periodized 4-week hypertrophy and strength blocks (8 weeks in total). Following this, for the final 4-week power training block, the cohort was separated into either TS (n = 11) or CL (n = 11) set structures. CL were prescribed by including 45-second intra-set rest every two repetitions. One-repetition maximum (1RM) and peak barbell velocities …

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Excitatory Drive To Spinal Motoneurones Is Necessary For Serotonin To Modulate Motoneurone Excitability Via 5-Ht2 Receptors In Humans, Tyler T. Henderson, Janet L. Taylor, Jacob R. Thorstensen, Justin J. Kavanagh Jan 2024

Excitatory Drive To Spinal Motoneurones Is Necessary For Serotonin To Modulate Motoneurone Excitability Via 5-Ht2 Receptors In Humans, Tyler T. Henderson, Janet L. Taylor, Jacob R. Thorstensen, Justin J. Kavanagh

Research outputs 2022 to 2026

Serotonin modulates corticospinal excitability, motoneurone firing rates and contractile strength via 5-HT2 receptors. However, the effects of these receptors on cortical and motoneurone excitability during voluntary contractions have not been explored in humans. Therefore, the purpose of this study was to investigate how 5-HT2 antagonism affects corticospinal and motoneuronal excitability with and without descending drive to motoneurones. Twelve individuals (aged 24 ± 4 years) participated in a double-blind, placebo-controlled, crossover study, whereby the 5-HT2 antagonist cyproheptadine was administered. Transcranial magnetic stimulation (TMS) was delivered to the motor cortex to produce motor evoked potentials (MEPs), and electrical stimulation at the cervicomedullary …

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Hidden And Unacknowledged: The Mental Health And Psychosocial Interventions Delivered By School Nurses In Western Australia, Anita Moyes, Shirley Mcgough, Dianne Wynaden Jan 2024

Hidden And Unacknowledged: The Mental Health And Psychosocial Interventions Delivered By School Nurses In Western Australia, Anita Moyes, Shirley Mcgough, Dianne Wynaden

Research outputs 2022 to 2026

Schools are an important setting for the early identification, assessment and intervention of mental health problems in children and young people. Internationally, many nurses work in schools, but the role of this group with young people experiencing mental health problems has had only limited investigation. This study explored the activities school nurses undertook with young people experiencing mental health problems in Australia. Reporting was guided by the COREQ checklist. Thirty-one nurses participated in a semi-structured interview. Data were analysed using the constant comparative method of analysis as developed by Glaser and Strauss (1967). The findings identified that nurses working in …

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In Vivo Human Medial Gastrocnemius Fascicle Behaviour And Belly Gear During Submaximal Eccentric Contractions Are Not Affected By Concentric Fatiguing Exercise, Matheus Daros Pinto, Kazunori Nosaka, Anthony J. Blazevich Jan 2024

In Vivo Human Medial Gastrocnemius Fascicle Behaviour And Belly Gear During Submaximal Eccentric Contractions Are Not Affected By Concentric Fatiguing Exercise, Matheus Daros Pinto, Kazunori Nosaka, Anthony J. Blazevich

Research outputs 2022 to 2026

Changes in muscle geometry and belly gearing during eccentric contractions influence fibre strain and susceptibility to muscle damage. They are modulated by the interaction between connective tissues and intracellular-intrafascicular fluid pressures and external pressures from neighbouring structures. Fatiguing exercise triggers fluid shifts (muscle swelling) and muscle activation changes that may influence these modulators. Our purpose was to measure medial gastrocnemius (MG) geometric changes in vivo during eccentric contractions before and after maximal concentric muscle work to test the hypothesis that fatigue would reduce fascicle rotation and muscle gear and provoke greater fascicle strain. Submaximal eccentric plantar flexor contractions at 40% …

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Predicting Neurodegeneration From Sleep Related Biofluid Changes, Yue Yang, Woojin S. Kim, Johannes C. Michaelian, Simon J. G. Lewis, Craig L. Phillips, Angela L. D'Rozario, Pratishtha Chatterjee, Ralph N. Martins, Ron Grunstein, Glenda M. Halliday, Sharon L. Naismith Jan 2024

Predicting Neurodegeneration From Sleep Related Biofluid Changes, Yue Yang, Woojin S. Kim, Johannes C. Michaelian, Simon J. G. Lewis, Craig L. Phillips, Angela L. D'Rozario, Pratishtha Chatterjee, Ralph N. Martins, Ron Grunstein, Glenda M. Halliday, Sharon L. Naismith

Research outputs 2022 to 2026

Sleep-wake disturbances are common in neurodegenerative diseases and may occur years before the clinical diagnosis, potentially either representing an early stage of the disease itself or acting as a pathophysiological driver. Therefore, discovering biomarkers that identify individuals with sleep-wake disturbances who are at risk of developing neurodegenerative diseases will allow early diagnosis and intervention. Given the association between sleep and neurodegeneration, the most frequently analyzed fluid biomarkers in people with sleep-wake disturbances to date include those directly associated with neurodegeneration itself, such as neurofilament light chain, phosphorylated tau, amyloid-beta and alpha-synuclein. Abnormalities in these biomarkers in patients with sleep-wake disturbances …

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Topical Antibiotics Prophylaxis For Infections Of Indwelling Pleural/Peritoneal Catheters (Tap-Ipc): A Pilot Study, Estee P. M. Lau, Sam Faber, Chloe Charlesworth, Sue Morey, Sona Vekaria, Pierre Filion, Aron Chakera, Y. C.Gary Lee Jan 2024

Topical Antibiotics Prophylaxis For Infections Of Indwelling Pleural/Peritoneal Catheters (Tap-Ipc): A Pilot Study, Estee P. M. Lau, Sam Faber, Chloe Charlesworth, Sue Morey, Sona Vekaria, Pierre Filion, Aron Chakera, Y. C.Gary Lee

Research outputs 2022 to 2026

Background and Objective: Indwelling pleural catheter (IPC) and indwelling peritoneal catheter (IPeC) have established roles in the management of malignant pleural and peritoneal effusions but catheter-related infections remain a major concern. Topical mupirocin prophylaxis has been shown to reduce peritoneal dialysis catheter infections. This study aimed to assess the (i) compatibility of IPC with mupirocin and (ii) feasibility, tolerability and compliance of topical mupirocin prophylaxis in patients with an IPC or IPeC. Methods: (i) Three preparations of mupirocin were applied onto segments of IPC thrice weekly and examined with scanning electron microscope (SEM) at different time intervals. (ii) Consecutive patients …

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Development Of A Regional Climate Change Model For Aedes Vigilax And Aedes Camptorhynchus (Diptera: Culicidae) In Perth, Western Australia, Kerry Staples, Peter J. Neville, Steven Richardson, Jacques Oosthuizen Jan 2024

Development Of A Regional Climate Change Model For Aedes Vigilax And Aedes Camptorhynchus (Diptera: Culicidae) In Perth, Western Australia, Kerry Staples, Peter J. Neville, Steven Richardson, Jacques Oosthuizen

Research outputs 2022 to 2026

Mosquito-borne disease is a significant public health issue and within Australia Ross River virus (RRV) is the most reported. This study combines a mechanistic model of mosquito development for two mosquito vectors; Aedes vigilax and Aedes camptorhynchus, with climate projections from three climate models for two Representative Concentration Pathways (RCPs), to examine the possible effects of climate change and sea-level rise on a temperate tidal saltmarsh habitat in Perth, Western Australia. The projections were run under no accretion and accretion scenarios using a known mosquito habitat as a case study. This improves our understanding of the possible implications of sea-level …

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Editorial: Neurotoxins In Alzheimer's Disease And Other Dementias, Alexandre Henriques, Philippe L. L. Poindron, Binosha Fernando, Kevin N. Hascup Jan 2024

Editorial: Neurotoxins In Alzheimer's Disease And Other Dementias, Alexandre Henriques, Philippe L. L. Poindron, Binosha Fernando, Kevin N. Hascup

Research outputs 2022 to 2026

Alzheimer's disease (AD) and other dementias are neurodegenerative disorders characterized by a progressive decline in cognition and independence from activities of daily living. Dementia is multifactorial with numerous risk factors including age, genes, molecules, lifestyle, and environmental contributions to disease onset and progression. In recent years, an emerging focus on neurotoxins has added a new layer of complexity to our understanding of dementia. This editorial aims to discuss recent updates regarding the role of neurotoxins in the pathogenesis of dementia.

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Metagenomic Characterisation Of The Gut Microbiome And Effect Of Complementary Feeding On Bifidobacterium Spp. In Australian Infants, Kimberley Parkin, Debra J. Palmer, Valerie Verhasselt, Nelly Amenyogbe, Matthew N. Cooper, Claus T. Christophersen, Susan L. Prescott, Desiree Silva, David Martino Jan 2024

Metagenomic Characterisation Of The Gut Microbiome And Effect Of Complementary Feeding On Bifidobacterium Spp. In Australian Infants, Kimberley Parkin, Debra J. Palmer, Valerie Verhasselt, Nelly Amenyogbe, Matthew N. Cooper, Claus T. Christophersen, Susan L. Prescott, Desiree Silva, David Martino

Research outputs 2022 to 2026

Complementary feeding induces dramatic ecological shifts in the infant gut microbiota toward more diverse compositions and functional metabolic capacities, with potential implications for immune and metabolic health. The aim of this study was to examine whether the age at which solid foods are introduced differentially affects the microbiota in predominantly breastfed infants compared with predominantly formula-fed infants. We performed whole-genome shotgun metagenomic sequencing of infant stool samples from a cohort of six-month-old Australian infants enrolled in a nested study within the ORIGINS Project longitudinal birth cohort. Infants born preterm or those who had been administered antibiotics since birth were excluded. …

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Neuropsychiatric Symptoms Of Dementia In Those With And Without A Recorded History Of Psychological Trauma: A Comparative Study From An Australian Dementia Support Service, Monica Cations, Mustafa Atee, Thomas Morris, Daniel Whiting Jan 2024

Neuropsychiatric Symptoms Of Dementia In Those With And Without A Recorded History Of Psychological Trauma: A Comparative Study From An Australian Dementia Support Service, Monica Cations, Mustafa Atee, Thomas Morris, Daniel Whiting

Research outputs 2022 to 2026

Objective: To compare the number and severity of neuropsychiatric symptoms (NPS) and associated caregiver distress between those with and without a noted history of psychological trauma among those referred to a specialised national dementia NPS support service. Methods: This was a 5-year retrospective observational study of records from the Dementia Support Australia NPS support service. NPS were reported by formal or informal caregivers at service entry using the Neuropsychiatric Inventory Nursing Home version or Questionnaire version. A history of psychological trauma was recorded in the person's social or medical history and/or endorsed as a contributor to NPS by a trained …

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Pain Is Underestimated In Older Adults With Risk Of Falls, Mustafa Atee Jan 2024

Pain Is Underestimated In Older Adults With Risk Of Falls, Mustafa Atee

Research outputs 2022 to 2026

Dear Editor, I have read with great interest the Xiao et al. study examining ret-rospectively the incidence of falls and related factors in outpatient and inpatient elderly sample (n= 451) aged 65 years and above. . . .

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Quantifying Uptake And Completion Of Pulmonary Rehabilitation Programs In People With Chronic Obstructive Pulmonary Disease Known To Tertiary Care, Sarah Hug, Vinicius Cavalheri, Daniel F. Gucciardi, Kylie Hill Jan 2024

Quantifying Uptake And Completion Of Pulmonary Rehabilitation Programs In People With Chronic Obstructive Pulmonary Disease Known To Tertiary Care, Sarah Hug, Vinicius Cavalheri, Daniel F. Gucciardi, Kylie Hill

Research outputs 2022 to 2026

Background: People with symptomatic chronic obstructive pulmonary disease (COPD) benefit from pulmonary rehabilitation programs (PRPs), but program attrition is common. Methods: For people with COPD who presented to tertiary care and appeared appropriate for a PRP, we prospectively mapped their PRP journey, explored factors influencing attendance to pre-program assessment and captured program attrition. Results: Of the 391 participants, 31% (95% CI 27 to 36) were referred to a PRP (n = 123; age 68 ± 10years, 62 males [50%], FEV1 45 ± 19%predicted). Of those referred, 94 (76% [69 to 84]) attended a pre-program assessment. Ex-smokers and those who had …

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The Benefits, Barriers And Facilitators Of Mentoring Programs For First-Year Doctors: A Systematic Review, Joelle Winderbaum, Linda L. L. Coventry Jan 2024

The Benefits, Barriers And Facilitators Of Mentoring Programs For First-Year Doctors: A Systematic Review, Joelle Winderbaum, Linda L. L. Coventry

Research outputs 2022 to 2026

Introduction: The transition from medical student to first-year doctor is notoriously difficult, yielding a high rate of transition failure, burn-out and mental health deterioration. Doctors in this cohort experience unique challenges during this time, which manifest through performance gaps, issues of professional identity, new occupational pressures, and cultural expectations. Mentoring programs are commonly utilised in the medical profession to foster personal and professional development and improve psychosocial well-being and career satisfaction. However, there exist no systematic reviews examining the use of mentorship specifically for the first-year doctor cohort, given the unique transition challenges faced by this vulnerable group. Purpose: Due …

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The Report Of Access And Engagement With Digital Health Interventions Among Children And Young People: Systematic Review, Lisa Whitehead, Suzanne Robinson, Diana Arabiat, Mark Jenkins, Evalotte Morelius Jan 2024

The Report Of Access And Engagement With Digital Health Interventions Among Children And Young People: Systematic Review, Lisa Whitehead, Suzanne Robinson, Diana Arabiat, Mark Jenkins, Evalotte Morelius

Research outputs 2022 to 2026

Background: Digital health interventions are increasingly used to deliver health-related interventions for children and young people to change health behaviors and improve health outcomes. Digital health interventions have the potential to enhance access to and engagement with children and young people; however, they may also increase the divide between those who can access technology and are supported to engage and those who are not. This review included studies that reported on the access to or engagement with digital health interventions among children and young people. Objective: This review aims to identify and report on access and engagement in studies involving …

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Exercise Professional Education, Qualifications, And Certifications: A Content Analysis Of Job Postings In The United States, Rachele Pojednic, Devin P. O’Neill, Molly G. Flanagan, Alexis Bartlett, Byron L. G. Carter, Mary A. Kennedy Jan 2024

Exercise Professional Education, Qualifications, And Certifications: A Content Analysis Of Job Postings In The United States, Rachele Pojednic, Devin P. O’Neill, Molly G. Flanagan, Alexis Bartlett, Byron L. G. Carter, Mary A. Kennedy

Research outputs 2022 to 2026

Introduction: Growth in the field of clinical exercise science and the potential impacts on overall health and wellbeing have driven the need for qualified, clinically trained, exercise professionals. And yet, it is not well understood what specific credentials employers are seeking when hiring exercise professionals. Purpose: The purpose of the study was to examine the qualification requirements for professionals seeking employment in exercise science, exercise physiology, kinesiology or equivalent fields. Methods: Search platforms Indeed.com and USAJobs.gov were examined within a two week period in 2022. Search terms included “Exercise Physiology”, “Exercise Science”, “Exercise Professional”, “Exercise Prescription”, “Exercise Specialist”, and “Kinesiology”. …

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Reduction And Recovery Of Self-Sustained Muscle Activity After Fatiguing Plantar Flexor Contractions, Anthony J. Blazevich, Ricardo N. O. Mesquita, Ronei S. Pinto, Timothy Pulverenti, Sébastien Ratel Jan 2024

Reduction And Recovery Of Self-Sustained Muscle Activity After Fatiguing Plantar Flexor Contractions, Anthony J. Blazevich, Ricardo N. O. Mesquita, Ronei S. Pinto, Timothy Pulverenti, Sébastien Ratel

Research outputs 2022 to 2026

Purpose: Persistent inward calcium and sodium currents (PICs) are crucial for initiation and maintenance of motoneuron firing, and thus muscular force. However, there is a lack of data describing the effects of fatiguing exercise on PIC activity in humans. We simultaneously applied tendon vibration and neuromuscular electrical stimulation (VibStim) before and after fatiguing exercise. VibStim induces self-sustained muscle activity that is proposed to result from PIC activation. Methods: Twelve men performed 5-s maximal isometric plantar flexor contractions (MVC) with 5-s rests until joint torque was reduced to 70%MVC. VibStim trials consisted of five 2-s trains of neuromuscular electrical stimulation (20 …

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Summary Of Aboriginal And Torres Strait Islander Health Status - Selected Topics 2023, Australian Indigenous Healthinfonet Jan 2024

Summary Of Aboriginal And Torres Strait Islander Health Status - Selected Topics 2023, Australian Indigenous Healthinfonet

Research outputs 2022 to 2026

Aboriginal and Torres Strait Islander people have lived on their traditional lands across Australia, including the Torres Strait Islands, for upwards of 50,000 years and their continuity, history and cultural traditions are unrivalled in the world [1,2] . Before colonisation, Aboriginal and Torres Strait Islander people lived in family and community groups, and moved across the land following seasonal changes [1] . Aboriginal and Torres Strait Islander people developed complex societies, trading systems and agricultural activities that were celebrated and recorded in dance, song and stories [2] . The Aboriginal and Torres Strait Islander concept of health is not just …

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Different Methods Of Winning, Losing, And Training In Combat Sports And Their Relationship With Overall Competitive Winningness, Oliver R. Barley, Craig A. Harms Jan 2024

Different Methods Of Winning, Losing, And Training In Combat Sports And Their Relationship With Overall Competitive Winningness, Oliver R. Barley, Craig A. Harms

Research outputs 2022 to 2026

This study aimed to investigate how overall competitive winningness in combat sports depended on patterns of victory and loss, as well as training habits. Competitors (N = 280) from several combat sports participated in the study. The online survey included questions on self-reported patterns of victory (and loss), training habits, general demographics (e.g., age), and sport-specific information (e.g., stage of career and competitive style). Overall, it was found across four models that reflected diversity of winningness in combat sports that the most important predictors of competitive winningness were loss by points (negative), loss by submission (negative), loss (negative) or victory …

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Enabling Ai And Robotic Coaches For Physical Rehabilitation Therapy: Iterative Design And Evaluation With Therapists And Post-Stroke Survivors, Min Hun Lee, Daniel Siewiorek, Asim Smailagic, Alexandre Bernardino, Sergi Bermúdez I Badia Jan 2024

Enabling Ai And Robotic Coaches For Physical Rehabilitation Therapy: Iterative Design And Evaluation With Therapists And Post-Stroke Survivors, Min Hun Lee, Daniel Siewiorek, Asim Smailagic, Alexandre Bernardino, Sergi Bermúdez I Badia

Research Collection School Of Computing and Information Systems

Artificial intelligence (AI) and robotic coaches promise the improved engagement of patients on rehabilitation exercises through social interaction. While previous work explored the potential of automatically monitoring exercises for AI and robotic coaches, the deployment of these systems remains a challenge. Previous work described the lack of involving stakeholders to design such functionalities as one of the major causes. In this paper, we present our efforts on eliciting the detailed design specifications on how AI and robotic coaches could interact with and guide patient’s exercises in an effective and acceptable way with four therapists and five post-stroke survivors. Through iterative …

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Envisaging A Thriving Future: The Integration Of Positive Psychology Into Brief Psychotherapy And Family Therapy Practice, Richard Lakeman Jan 2024

Envisaging A Thriving Future: The Integration Of Positive Psychology Into Brief Psychotherapy And Family Therapy Practice, Richard Lakeman

Research outputs 2022 to 2026

This paper delves into the pragmatic integration of positive psychology, particularly Seligman's PERMA model, and brief psychotherapy to foster a vision of a thriving future for clients. Despite the entrenched tribalism within psychotherapy that often resists the incorporation of new techniques, a deliberate and flexible approach to integration, rooted in congruence with theoretical frameworks, can overcome these barriers. Positive psychology dovetails neatly with the goals of family therapy by highlighting strengths and resilience. The PERMA model—encompassing Positive emotions, Engagement, Relationships, Meaning and Accomplishment—captures the essence of a flourishing life. While primarily applied in non-clinical settings, its potential to enhance wellbeing …

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Examining The Effects Of Dynamic And Isometric Resistance Training On Knee Joint Kinetics During Unplanned Sidesteps In Elite Female Athletes, Daniel Kadlec, Matthew J. Jordan, Jacqueline Alderson, Sophia Nimphius Jan 2024

Examining The Effects Of Dynamic And Isometric Resistance Training On Knee Joint Kinetics During Unplanned Sidesteps In Elite Female Athletes, Daniel Kadlec, Matthew J. Jordan, Jacqueline Alderson, Sophia Nimphius

Research outputs 2022 to 2026

Kadlec, D, Jordan, MJ, Alderson, J, and Nimphius, S. Examining the effects of dynamic and isometric resistance training on knee joint kinetics during unplanned sidesteps in elite female athletes. J Strength Cond Res XX(X): 000-000, 2024 - The purpose of this study was to examine the effects of a 4-week block of isometric (isometricRT) and dynamic resistance training (dynamicRT) on kinetic variables associated with anterior cruciate ligament (ACL) injury risk during unplanned sidesteps in elite female athletes. Twenty-one elite female athletes competing for a women's international rugby union team were recruited with 15 (n = 15; age: 23.4 ± 4.7 …

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Exploration Of Alzheimer's Disease-Related Gene Expression Following High-Intensity And Moderate-Intensity Exercise Interventions, Kieran J. Marston, Jaisalmer De Frutos-Lucas, Tenielle Porter, Lidija Milicic, Michael Vacher, Kelsey R. Sewell, Jeremiah J. Peiffer, Simon M. Laws, Belinda M. Brown Jan 2024

Exploration Of Alzheimer's Disease-Related Gene Expression Following High-Intensity And Moderate-Intensity Exercise Interventions, Kieran J. Marston, Jaisalmer De Frutos-Lucas, Tenielle Porter, Lidija Milicic, Michael Vacher, Kelsey R. Sewell, Jeremiah J. Peiffer, Simon M. Laws, Belinda M. Brown

Research outputs 2022 to 2026

Objectives: There are currently 29 genome regions that demonstrate associations with Alzheimer's disease (AD) risk. Regular physical exercise can promote systemic change in gene expression and may modify the risk of cognitive decline and AD. This study is a secondary analysis of a randomised controlled trial and examines the effect of a six-month exercise intervention versus control on AD-related gene expression. Design: Single-site parallel pilot randomised controlled trial. Methods: 91 cognitively unimpaired older adults were enrolled in the Intense Physical Activity and Cognition (IPAC) study. Participants were randomised into one of three groups: high-intensity exercise, moderate-intensity exercise, or inactive control …

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Exploring The Health Benefits Of Raw White Garlic Consumption In Humans: A Mini Review, Rebeka Fejes, Catherine P. Bondonno, Simone Radavelli-Bagatini, Tilman Kühn, Karl Heinz Wagner Jan 2024

Exploring The Health Benefits Of Raw White Garlic Consumption In Humans: A Mini Review, Rebeka Fejes, Catherine P. Bondonno, Simone Radavelli-Bagatini, Tilman Kühn, Karl Heinz Wagner

Research outputs 2022 to 2026

Introduction: Raw white garlic, a fundamental food in both culinary and medicinal practices globally, has gained attention for its potential health benefits. Despite widespread use, clinical research has predominantly focused on aged black garlic or garlic extracts, leaving raw white garlic consumption in humans underexplored. This mini review aims to summarize the evidence from clinical and observational studies on the health effects of raw white garlic consumption. Methods: A search in PubMed and Scopus databases was conducted to identify clinical and observational studies on raw white garlic consumption. Twelve clinical trials and 10 observational studies meeting the predefined inclusion criteria …

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Lessons Learned: Drive-Through Covid-19 Clinic Testing During An Adaptive Epidemic Response And A Point-Of-Care Test Assessment Of A Computer-Read Rapid Lateral Flow Immunoassay With Fluorescence-Based Detection, Leah Rankine-Wilson, Teresa Oncken, Irshan Basrewan, Courtney Jeffery, Todd M. Pryce, Rebecca Wake, Aus A.L. Molan, T. F. Paton, Tim J.J. Inglis Jan 2024

Lessons Learned: Drive-Through Covid-19 Clinic Testing During An Adaptive Epidemic Response And A Point-Of-Care Test Assessment Of A Computer-Read Rapid Lateral Flow Immunoassay With Fluorescence-Based Detection, Leah Rankine-Wilson, Teresa Oncken, Irshan Basrewan, Courtney Jeffery, Todd M. Pryce, Rebecca Wake, Aus A.L. Molan, T. F. Paton, Tim J.J. Inglis

Research outputs 2022 to 2026

Background. The COVID-19 pandemic demonstrated a need for robust SARS-CoV-2 test evaluation infrastructure to underpin biosecurity and protect the population during a pandemic health emergency. Gap statement. The first generation of rapid antigen tests was less accurate than molecular methods due to their inherent sensitivity and specificity shortfalls, compounded by the consequences of self-testing. This created a need for more accurate point-of-care SARS-CoV-2 detection methods. Aim. Here we present the lessons-learned during the COVID-19 emergency response in Western Australia including the detailed set-up, evaluation and operation of rapid antigen test in a state-run drive-through sample collection service during the COVID-19 …

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Measuring Attitude Change In Nursing Students After Completion Of A First Nations Peoples’ Health Unit: Embedding A Validated Tool In Learning And Assessment Practices, Kylie Mccullough, Angela Genoni, Melanie Murray, Darren Garvey, Linda Coventry Jan 2024

Measuring Attitude Change In Nursing Students After Completion Of A First Nations Peoples’ Health Unit: Embedding A Validated Tool In Learning And Assessment Practices, Kylie Mccullough, Angela Genoni, Melanie Murray, Darren Garvey, Linda Coventry

Research outputs 2022 to 2026

The health inequities experienced by Aboriginal and Torres Strait Islander peoples, rooted in the historical and ongoing negative impacts of colonisation and disrupted traditional lifestyles, sees higher rates of illness and hospitalisations, increased morbidity and higher premature death rates than other Australians. Nurses represent the majority of Australia’s health workforce and nursing students must have knowledge to provide culturally safe care to Australia’s Aboriginal and Torres Strait Islander peoples. An Aboriginal and Torres Strait Islander Peoples’ Health and Wellbeing unit was developed and introduced into an undergraduate nursing curriculum. This project aimed to determine the effectiveness of the unit content …

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Predictive Modelling Of Metabolic Syndrome In Ghanaian Diabetic Patients: An Ensemble Machine Learning Approach, Emmanuel Acheampong, Eric Adua, Christian Obirikorang, Enoch Odame Anto, Emmanuel Peprah-Yamoah, Yaa Obirikorang, Evans Adu Asamoah, Victor Opoku-Yamoah, Michael Nyantakyi, John Taylor, Tonnies Abeku Buckman, Maryam Yakubu, Ebenezer Afrifa-Yamoah Jan 2024

Predictive Modelling Of Metabolic Syndrome In Ghanaian Diabetic Patients: An Ensemble Machine Learning Approach, Emmanuel Acheampong, Eric Adua, Christian Obirikorang, Enoch Odame Anto, Emmanuel Peprah-Yamoah, Yaa Obirikorang, Evans Adu Asamoah, Victor Opoku-Yamoah, Michael Nyantakyi, John Taylor, Tonnies Abeku Buckman, Maryam Yakubu, Ebenezer Afrifa-Yamoah

Research outputs 2022 to 2026

Objectives: The burgeoning prevalence of cardiometabolic disorders, including type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) within Africa is concerning. Machine learning (ML) techniques offer a unique opportunity to leverage data-driven insights and construct predictive models for MetS risk, thereby enhancing the implementation of personalised prevention strategies. In this work, we employed ML techniques to develop predictive models for pre-MetS and MetS among diabetic patients. Methods: This multi-centre cross-sectional study comprised of 919 T2DM patients. Age, gender, novel anthropometric indices along with biochemical measures were analysed using BORUTA feature selection and an ensemble majority voting classification model, which included …

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Self-Efficacy And Home Dialysis: An Integrative Review, Nicola A. D'Souza, Ma'en Zaid Abu-Qamar, Lisa Whitehead Jan 2024

Self-Efficacy And Home Dialysis: An Integrative Review, Nicola A. D'Souza, Ma'en Zaid Abu-Qamar, Lisa Whitehead

Research outputs 2022 to 2026

Background: Enhancing patient confidence in their ability (self-efficacy) is vital to ensure people are equipped to maintain home dialysis protocols. Bandura's social cognitive theory provided a framework for understanding the role of self-efficacy in patients managing home dialysis. Objectives: To identify self-reported levels of self-efficacy, the measurements used to assess self-efficacy and the effectiveness of interventions to enhance self-efficacy in patients undergoing home dialysis. Design: An integrative review approach was employed using Whittemore and Knafl's methodology. Methods: A comprehensive search was conducted to identify literature on self-efficacy in patients managing home dialysis. Searches were conducted in CINAHL, MEDLINE, Embase and …

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The Integrated Behavioral Model Of Mental Health Help Seeking (Ibm-Hs): A Health Services Utilization Theory Of Planned Behavior For Accessing Care, Joseph H. Hammer, David L. Vogel, Patrick R. Grzanka, Nayeon Kim, Brian T. Keum, Claire Adams, Sarah A. Wilson Jan 2024

The Integrated Behavioral Model Of Mental Health Help Seeking (Ibm-Hs): A Health Services Utilization Theory Of Planned Behavior For Accessing Care, Joseph H. Hammer, David L. Vogel, Patrick R. Grzanka, Nayeon Kim, Brian T. Keum, Claire Adams, Sarah A. Wilson

Research outputs 2022 to 2026

This article introduces the integrated behavioral model of mental health help seeking (IBM-HS), a theoretical model for understanding the constructs (e.g., systemic, predisposing, and enabling factors; mental health literacy; illness perceptions; perceived need; stigma; shame; perceived benefits, motivation) that influence people’s decision making around seeking professional mental health care and their ultimate access to formal treatment. The IBM-HS is a help-seeking-specific adaptation of the empirically supported integrated behavioral model and integrative model, which are themselves evolutions of the theory of planned behavior and theory of reasoned action. The IBM-HS posits that help-seeking determinants (e.g., structural forces; cultural influences; past help-seeking …

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