Medicine and Health Sciences Commons^™

How Literacy Coursework May Change The Perspectives Of Preservice Speech-Language Pathologists: A Pilot Study, Robyn Becker

Department of Communication Sciences and Disorders Faculty Scholarship and Creative Works

This pilot study investigated how perspectives of preservice speech-language pathologists (SLPs) may change after completion of a graduate course in literacy in a Communication Sciences and Disorders (CSD) program. Further, the study sought to reflect upon course design and instructional delivery practices related to the class. Data was collected via online survey completed by 21 volunteer CSD graduate students. The results suggested that students' perspectives may evolve over the course of a semester-long CSD literacy class in some areas related to the components of reading, misconceptions about literacy, and the social justice implications of access to quality reading programs. Using …

Gene Expression Of Tight Junctions In Foreskin Is Not Affected By Hiv Pre-Exposure Prophylaxis, Emily L. Webb, Stefan Petkov, Heejin Yun, Laura Else, Limakatso Lebina, Jennifer Serwanga, Azure-Dee A.P. Pillay, Thabiso B. Seiphetlo, Susan Mugaba, Patricia Namubiru, Geoffrey Odoch, Daniel Opoka, Andrew S. Ssemata, Pontiano Kaleebu, Saye Khoo, Neil Martinson, Julie Fox, Clive M. Gray, Carolina Herrera, Francesca Chiodi

Department of Obstetrics & Gynecology Faculty Publications

Introduction: Tight junctions (TJs) serve as permeability filters between the internal and external cellular environment. A large number of proteins have been identified to be localized at the TJs. Due to limitations in tissue collection, TJs in the male genital tract have been understudied.

Methods: We analysed the transcriptomics of 132 TJ genes in foreskin tissue of men requesting voluntary medical male circumcision (VMMC) and enrolled in the Combined HIV Adolescent Prevention Study (CHAPS) trial conducted in South Africa and Uganda (NCT03986970). The trial evaluated the dose requirements for event-driven HIV pre-exposure prophylaxis (PrEP) with emtricitabine-tenofovir (FTC-TDF) or emtricitabine-tenofovir alafenamide …

Analysis Of The Immune Response After Readministration Of A Novel Aav6 Gene Therapy Containing Tlr9 Inhibitory Sequences, Sarah Elysse Allen

MUSC Theses and Dissertations

Therapeutic options for the treatment of Surfactant Protein-B (SP-B) deficiency, an autosomal recessive disorder that leads to fatal respiratory distress, are extremely limited with the exception of double lung transplantation. One method for treating this monogenic lung disease is with adeno-associated virus (AAV) gene therapy treatment that delivers the hSFTPB transgene into the lungs. The transient nature of AAV transgene expression led to a need for sustained gene expression, which could possibly be achieved through redosing. The main obstacle with redosing is the innate immune response and subsequent inflammatory response pathways that are activated after recognition of unmethylated CpG motifs …

Prevalence And Determinants Of Diarrhoea And Acute Respiratory Infections Among Children Aged Under Five Years In West Africa: Evidence From Demographic And Health Surveys, Derrick Nyantakyi Owusu, Henry Ofori Duah, Duah Dwomoh, Yakubu Alhassan

College of Nursing Faculty Research and Publications

Background Diarrhoea and pneumonia are the leading causes of morbidity and mortality in children aged < 5 y (under five) globally. This study sought to investigate the prevalence and determinants of diarrhoea and acute respiratory infections (ARIs) among children under five in West Africa. Methods The most recent demographic and health survey (DHS) standard for 13 West African countries was used in the study. We calculated the prevalence of diarrhoea and ARIs (2 wk prior to the survey) and performed multivariable complex logistic regression analysis to identify possible predictors of diarrhoea and ARIs. Results The weighted prevalence of diarrhoea and ARI was 13.7% and 15.9%, respectively. The prevalence of comorbid diarrhoea and ARI was 4.4%. Children aged < 2 y (p< 0.001), mothers aged < 30 y (p< 0.003), mothers without formal education (p< 0.001), poor households (p< 0.001) and poor nutritional status, wasting (p=0.005) and underweight (p< 0.001), were the independent predictors of diarrhoea. The independent predictors of ARIs were children with no childhood vaccinations (p=0.002), use of solid fuel in the household (p=0.007), being underweight (p=0.05) and diarrhoea (p< 0.001). Conclusions The findings imply the need for holistic public health interventions such as increased vaccination coverage, population-based nutritional programmes and campaigns on the use of cleaner cooking fuel targeted at high-risk subgroups in the population to reduce the burden and adverse effects of diarrhoea and ARIs in the West African region.

Predicting Radiation-Induced Immune Suppression In Lung Cancer Patients Treated With Stereotactic Body Radiation Therapy, Jonathan Colen, Cam Nguyen, Seth W. Liyanage, Eric Aliotta, Joe Chen, Clayton Alonso, Kara Romano, Sean Peach, Timothy Showalter, Paul Read, James Larner, Krishni Wijesooriya

Data Science Faculty Publications

BACKGROUND: Stereotactic body radiation therapy (SBRT) is known to modulate the immune system and contribute to the generation of anti-tumor T cells and stimulate T cell infiltration into tumors. Radiation-induced immune suppression (RIIS) is a side effect of radiation therapy that can decrease immunological function by killing naive T cells as well as SBRT-induced newly created effector T cells, suppressing the immune response to tumors and increasing susceptibility to infections.

PURPOSE: RIIS varies substantially among patients and it is currently unclear what drives this variability. Models that can accurately predict RIIS in near real time based on treatment plan characteristics …

Metabolink Is A Novel Algorithm For Unveiling Cell-Specific Metabolic Pathways In Longitudinal Datasets, Jared Lichtarge, Gerarda Cappuccio, Soumya Pati, Alfred Kwabena Dei-Ampeh, Senghong Sing, Lihua Ma, Zhandong Liu, Mirjana Maletic-Savatic

Duncan NRI Faculty and Staff Publications

Introduction: In the rapidly advancing field of 'omics research, there is an increasing demand for sophisticated bioinformatic tools to enable efficient and consistent data analysis. As biological datasets, particularly metabolomics, become larger and more complex, innovative strategies are essential for deciphering the intricate molecular and cellular networks.

Methods: We introduce a pioneering analytical approach that combines Principal Component Analysis (PCA) with Graphical Lasso (GLASSO). This method is designed to reduce the dimensionality of large datasets while preserving significant variance. For the first time, we applied the PCA-GLASSO algorithm (i.e., MetaboLINK) to metabolomics data derived from Nuclear Magnetic Resonance (NMR) spectroscopy …

The Mediating Role Of Sense Of Coherence In The Relationship Between Positive Childhood Experiences And Alexithymia, Ummu Erturk Yıldız, İbrahim Taş

Khazar Journal of Humanities and Social Sciences

This study examined the mediating role of the sense of coherence in the relationship between positive childhood experiences and alexithymia. The research was conducted with a total of 507 participants, including 259 women and 248 men aged over 18, selected through convenience sampling. Data were collected using a Personal Information Form, the Positive Childhood Experiences Scale, the Toronto Alexithymia Scale, and the Sense of Coherence Scale. Data analysis was performed using SPSS 25 and the PROCESS macro. The results indicated that positive childhood experiences significantly and positively predicted levels of sense of coherence, while they significantly and negatively predicted alexithymia. …

Identification Of Culturable Bacteria, Delphine Lanoie, Thi Thanh Tam Nguyen, Audrey Bernèche-D'Amours

Microbiologiques

Cette méthode est utilisée pour identifier des bactéries cultivées à partir d’échantillons d’air, de surface ou provenant de procédés solides ou liquides. Après avoir isolé une souche bactérienne en culture pure, les caractères macroscopiques et microscopiques des colonies bactériennes sont observés et des tests biochimiques simples sont réalisés. L’identification finale pourra être réalisée en utilisant une ou plusieurs de ces techniques : par spectrométrie de masse utilisant la technologie MALDI-ToF, par séquençage de type Sanger du gène codant pour l’ARNr 16S ou en fonction des caractéristiques phénotypiques de la souche par le système Biolog (tests biochimiques).

Abstract

This method is …

Inflammation And Tumor Progression: The Differential Impact Of Saa In Breast Cancer Models, Daniel Wilhelm Olivier, Carla Eksteen, Manisha Du Plessis, Louis De Jager, Lize Engelbrecht, Nathaniel Wade Mcgregor, Preetha Shridas, Frederick C. De Beer, Willem J. S. De Villiers, Etheresia Pretorius, Anna-Mart Engelbrecht

Saha Cardiovascular Research Center Faculty Publications

Background: Previous research has shown that the Serum Amyloid A (SAA) protein family is intricately involved in inflammatory signaling and various disease pathologies. We have previously demonstrated that SAA is associated with increased colitis disease severity and the promotion of tumorigenesis. However, the specific role of SAA proteins in breast cancer pathology remains unclear. Therefore, we investigated the role of systemic SAA1 and SAA2 (SAA1/2) in a triple-negative breast cancer mouse model.

Methods: Syngeneic breast tumors were established in wild-type mice, and mice lacking the SAA1/2 (SAADKO). Subsequently, tumor volume was monitored, species survival determined, the inflammatory profiles of mice …

Novel Engineering Approaches For Orthopedic Injury Treatment And Infection Diagnosis, Cynthia Co

Bioengineering Dissertations - Archive

Bioengineering has made significant contributions to the treatment of orthopedic injury through interdisciplinary approaches. Central to these advancements are many orthopedic implants, including anchors and joint replacements, which have been designed to restore mobility. Despite their functional efficacy, these products have limited lifespan and are associated with many complications, such as implant-associated infection. The success of implant design and function, both in the short and long term, is paramount for enhancing patient outcomes and overall well-being. Therefore, my thesis work is dedicated to addressing these critical challenges, aiming to maximize their treatment effect while minimizing the implant-associated complications.

Long-term patient …

The Effect Of A Neonatal Palliative Care Education Program In Increasing Knowledge And Communication Self-Efficacy Among Nicu Nurses, Shiou-Huei Joy Wang

Doctoral Projects

Background: Neonatal palliative care is crucial to providing comprehensive, high-quality care to neonates with life-limiting or life-threatening health conditions and their families. One significant barrier to the inconsistent provision of neonatal palliative care is the lack of education. This project aimed to deliver an education training program to increase neonatal palliative care knowledge and self-efficacy in NICU nurses. Method: A pre-post-test study design was used to examine the efficacy of an educational training program on NICU nurses’ knowledge and communication self-efficacy in neonatal palliative care. A post-test was administered immediately after the training and again four weeks later to evaluate …

The Integrated Behavioral Model Of Mental Health Help Seeking (Ibm-Hs): A Health Services Utilization Theory Of Planned Behavior For Accessing Care, Joseph H. Hammer, David L. Vogel, Patrick R. Grzanka, Nayeon Kim, Brian T. Keum, Claire Adams, Sarah A. Wilson

Chemical and Materials Engineering Faculty Publications

This article introduces the integrated behavioral model of mental health help seeking (IBM-HS), a theoretical model for understanding the constructs (e.g., systemic, predisposing, and enabling factors; mental health literacy; illness perceptions; perceived need; stigma; shame; perceived benefits, motivation) that influence people’s decision making around seeking professional mental health care and their ultimate access to formal treatment. The IBM-HS is a help-seeking-specific adaptation of the empirically supported integrated behavioral model and integrative model, which are themselves evolutions of the theory of planned behavior and theory of reasoned action. The IBM-HS posits that help-seeking determinants (e.g., structural forces; cultural influences; past help-seeking …

Advocacy Spotlight: Telehealth Regulations For Dentistry Established, Neema Katibai Jd

The Journal of the Michigan Dental Association

The article discusses the rise of telehealth in the last three years and its implications for dentistry, focusing on recent rulemaking by the Michigan Board of Dentistry. The regulations address key aspects such as definitions, informed consent, scope of practice, and prescribing medications. Dentists must comply with HIPAA and state/federal privacy regulations when using telehealth. Notably, the rules restrict teledentistry delegation to allied personnel after an in-person visit within 24 months. The article emphasizes the importance of understanding and following these regulations for legal telehealth use, reimbursement, and malpractice coverage. The Michigan Dental Association advocates for sensible teledentistry laws to …

Staff Matters: Are There Risks To Using Ai In Our Practice?, Jodi Schafer Sphr, Shrm-Scp

The Journal of the Michigan Dental Association

As your practice adopts AI for hiring processes, it brings efficiency but also potential pitfalls. The increasing use of AI, such as ChatGPT, streamlines tasks like resume screening, but caution is essential. Recent executive orders emphasize safety assessments and civil rights in AI. The Equal Employment Opportunity Commission focuses on transparency and consent in recruitment AI use. Legal compliance is vital to prevent discrimination; criteria like education and experience must be applied consistently. Additionally, employee monitoring AI requires careful implementation, ensuring transparency and human oversight. While AI offers benefits, its workplace integration demands careful consideration, testing, and ongoing evaluation.

Mda Services: Yes, You Can Recoup Your Dues With Mda-Endorsed Programs, Reva Darling

The Journal of the Michigan Dental Association

MDA Services Report highlights how being an organized dentistry member can yield significant financial returns through MDA-endorsed products and services. By leveraging just eight of the 32 endorsed offerings, potential savings of $25,659 are achievable. Key endorsed services include Best Card for credit card processing, iCoreConnect for software needs, Quality Dental Plan for in-office dental plans, The Dentists Supply Company (TDSC.com) for supplies, ProSites for website and e-marketing, D-MMEX Easyrefine for precious metal refining, Eagle Associates for regulatory compliance, and Dental Business Specialists for accounting. Members are urged to explore the range of endorsed programs for comprehensive benefits.

Digital Health Care: Time For A New Standard?, Z K. Winkelmann

Clinical Practice in Athletic Training

Introduction: The rapid influx of digitalization in healthcare has presented opportunities for innovative engagement, delivery, and outcomes for patient care. However, it also presents with several barriers and challenges that require teaching and learning opportunities to prepare future athletic trainers for these tasks. Currently, the CAATE curricular content standards integrate digital health care through Standard 64 on health informatics and Standard 87 on biometrics. However, the art and science of digital healthcare are expansive, including various skills such as digital literacy, computer skills, online communication, and privacy and security standards. Methods: The presentation will provide an overview of current digital …

Burnout In Athletic Training: Measured By Survey In Most Common Settings For Athletic Trainers, R Johnson Krug, N Sand, S Brooks, T Smith

Clinical Practice in Athletic Training

Introduction: Burnout is a common problem in athletic training, affecting both athletic trainers (ATs) and the athletes they serve. Athletic trainers are responsible for the prevention, diagnosis, and treatment of sports-related injuries. Long work hours, often including evenings and weekends, as well as frequently under pressure to meet the demands of athletes, coaches, and parents. Athletic trainers face numerous stressors that contribute to burnout. These stressors may include heavy workloads, lack of control over their schedules, time pressures, and pressure to produce positive outcomes. Athletic trainers may also experience emotional and physical exhaustion, depersonalization, and a reduced sense of personal …

Educational Outcomes Of The Dat: A Document Review And Thematic Analysis, S H. Orr, L E. Eberman, M J. Rivera

Clinical Practice in Athletic Training

Context: The transition in athletic training education allows for unique and new opportunities in postprofessional education. The Doctor of Athletic Training (DAT) degree is one of the postprofessional education pathways that could provide athletic trainers advancement in clinical practice, practice leadership, and scholarship. However, there is no data on the educational outcomes of DAT programs and what graduates should expect from their experiences. The aim of this study was to explore whether DAT programs are delivering curricula consistent with the development of clinical scholars with advanced knowledge and skills that are needed for high-level patient care and literature relative to …

Athletic Trainers’ Familiarity With Potential Concussion Biomarkers: A Descriptive Study, T R. Campbell, B J. Davis, J C. Martinez, J M. Cavallario

Clinical Practice in Athletic Training

Introduction: An estimated 3.8 million individuals sustain a concussion annually in the United States. Despite the high number of cases, this number may not accurately depict the true incidence rate due to underreporting of symptoms by patients. With current concussion tools relying heavily on subjective input from patients, it is imperative that a valid and reliable objective tool, such as a clinical biomarker, is identified to improve concussion diagnosis and management. If such a biomarker is identified, it will be essential that athletic trainers (ATs) be familiar with how biomarkers could be used. The purpose of this study was to …

Athletic Training Preceptors’ Experience With Interprofessional Education And Collaborative Practice In The Clinical Learning Environment, A Bender

Clinical Practice in Athletic Training

Introduction: Professional athletic training (AT) programs are now required to align their educational curricula with the Institute of Medicine's (IOM) core competencies, preparing students to work in dynamic, interprofessional healthcare teams to strategically address patient outcomes. Although interprofessional education and collaborative practice (IPECP) is commonly implemented in didactic settings, our understanding of how IPECP is implemented by AT preceptors in various clinical settings is limited. The purpose of this study was to gain a greater understanding of AT preceptors’ experience with IPECP and how they implement this with students in their clinical settings. Methods: A convergent mixed-methods design was used …

Using Alums Involvement To Increase Student Investment In An Athletic Training Program, C J. Heffner, A L. Green

Clinical Practice in Athletic Training

Introduction: Student investment and retention are not new concerns among athletic training program directors. Graduate programs are expected to meet minimum enrollment standards to demonstrate the need for the program. Programs that are unable to maintain student enrollment will be eliminated by institutions experiencing financial stress. Retention strategies and benefits have previously been investigated among undergraduate students and across disciplines. One common theme in the research is that student retention increases when students feel a sense of belonging from the faculty, staff, and peers in their program. There is less research on the retention of graduate students, but the themes …

Using Data In The Classroom To Drive Instructional Design And Delivery, L E. Eberman, J P. Young

Clinical Practice in Athletic Training

Introduction: Roughly half of ATP program directors include education on transgender health care in their programs, and even fewer report having the competence to do so. However, professional-level accreditation standards (56, 57, and DEI 2) require that programs have faculty with contemporary expertise to educate students on these outcomes. Current research suggests a comprehensive transgender and sexual health curriculum, including safe-zone training, traditional lecture, lab, and project-based instruction, was partially effective at changing students’ attitudes toward transgender patients but did not improve sexual health care delivery during a standardized patient encounter. The purpose of this project was to evaluate the …

Traveling The Pathway To A Culturally Competent Health Care Provider: Incorporating Study Abroad Into Your Curriculum, A L. Johnston Green, C J. Heffner

Clinical Practice in Athletic Training

Introduction: As athletic training employment settings expand and diversify, so does the patient population with whom these healthcare providers interact. This growth furthers the need to ensure that students enrolled in an athletic training program (ATP) accredited by the Commission on Accreditation of Athletic Training Education (CAATE) are educated to provide culturally competent care. Culturally competent care is provided when decisions made diminish the inequalities that may be present in a system based upon a patient’s individual circumstances. Implementing cultural competency education may be integrated into athletic training education in various manners as necessitated by each institution’s unique circumstances. Programs …

Exploring The Work-Related Quality Of Life Of Athletic Trainers In Physician Practice, N T. Anderson, K E. Games, J P. Young, M J. Rivera, L E. Eberman

Clinical Practice in Athletic Training

Introduction/Context: The National Athletic Trainers’ Association (NATA) identified the vitality of the athletic training profession as a research priority, which includes exploring solutions to improve work-life balance. There is a common perception that athletic trainers (AT) working in the physician practice setting have lower work-life conflict and increased job satisfaction, but no data to support this belief. Work-Related Quality of Life (WRQoL) has been studied in some healthcare settings but has not been studied in any athletic training clinical practice setting. Therefore, the purpose of this study is to investigate the WRQoL of athletic trainers in physician practice. Methods: A …

How Do Athletic Trainers Impact Patient Health Literacy?: A Critically Appraised Topic, T Bouchard

Clinical Practice in Athletic Training

Introduction/Context: Health Literacy is defined as “the degree to which individuals have the capacity to obtain, process, and understand basic health information and services needed to make appropriate health decisions.” An estimated 80 million Americans are estimated to have low levels of health literacy. Low health literacy has been linked to poor patient outcomes and decreased usage of health services. Athletic trainers are multiskilled medical professionals recognized by the American Medical Association, trained in, among other things, wellness promotion and education, injury prevention and rehabilitation, and primary care. Although athletic trainers have traditionally been employed in collegiate/elite sports, many are …

An Exploration Of Mhealth Applications Usage Among Older Adults: A Mixed Methods Study, Francine N. Sutton

Graduate Thesis and Dissertation 2023-2024

This study examines the technology and appointment scheduling habits of older adults over the age of 55 through an exploratory sequential three phase mixed methods study. Phase One of this study examined features of ten existing mHealth applications through a qualitative content analysis, then a mHealth wireframe was developed from the app to replicate in addition to a redesigned version. Phase Two of the study was a thirty-four questions survey with 40 participants that inquired about their background with appointment scheduling, prior experience with technology, and demographics. After that, the mHealth applications were revised into two mHealth application prototypes. Lastly, …

I Am Not A Hero: Heroic Action Divorces The Hero From The Political Community, Ari Kohen, Brian Riches, Andre Sólo

Department of Political Science: Faculty Publications

Most people who perform a heroic act will, afterward, deny that their actions were heroic and claim that anyone would have done the same, even though that is demonstrably false (and, often, others were present who failed to act heroically at all). The literature on the psychology of heroism has never investigated why this is. This theoretical paper proposes an answer and seeks to provoke exploration of a previously unexplored topic. We note that people who undertake heroic action face a unique conflict: they embody their community’s highest values, while simultaneously breaking norms to stand apart from that community. We …

Efficacy Of Praziquantel In Treating Schistosoma Haematobium Infection Among Ethiopian Children, Louis Fok, David Brett-Major, Berhanu Erko, John Linville, Hongying Dai, Yohannes Negash, Abebe Animut, Abraham Degarege

Journal Articles: Epidemiology

Background/Objectives: Praziquantel is a cornerstone of schistosomiasis control and elimination efforts. Continued surveillance of praziquantel efficacy is needed to monitor for the development of resistance, as well as to help public health officials gauge the effect of mass praziquantel administration on schistosomiasis control in communities, since it is the only drug used in schistosomiasis control programs. The objective of this study was to assess the praziquantel cure rate and egg reduction rate against urogenital schistosomiasis.

Methods: This study enrolled 977 children from 12 villages in Afar and Gambella, Ethiopia, who provided urine samples that were checked for Schistosoma haematobium …

Aborted Confidentiality, Stacey A. Tovino

Faculty Articles

As the number of abortion-restricting laws continues to grow in the wake of the Supreme Court’s ruling in Dobbs v. Jackson Women’s Health Organization, law enforcement officers are increasingly interested in obtaining and using reproductive health information for law enforcement purposes. Although physicians and other covered entities generally are required to keep protected health information (PHI) confidential under the Health Insurance Portability and Accountability Act Privacy Rule, a number of regulatory exceptions historically have permitted covered entities to disclose PHI for civil, criminal, and administrative investigations and proceedings. On April 26, 2024, the Department of Health and Human Services …

Zeitlin’S Top 200 Dental Deckades (January 2024), Benjamin D. Zeitlin

Pacific Open Texts

Pharmacology courses in any institution are information intensive with a constant, high volume of new material. With that in mind, the standards that the American Dental Education Association set for Pharmacology include that: “the student must identify the influences drugs taken for non-dental purposes may have on a proposed treatment (…) and the student must recognize therapeutic agents used in the routine practice of clinical dentistry.” This requires that students at a minimum, recognize common drugs and know their major implications for dental therapy.

This learning tool has been created to address the drug recognition aspect of that standard.

See …