Medicine and Health Sciences Commons^™

Preparing Nursing Students To Manage Acculturative Stress Experienced During Study Abroad Experiences: Novel Use Of Immersive Simulation And Cognitive Behavioral Strategies, Theresa Schnable, Christine A. Schindler, Jeffrey D. Roche, Karli Webster, Christopher E. Larkee, Maharaj Singh, John F. Ladisa

College of Nursing Faculty Research and Publications

This pilot study adds to the understanding of interventions to manage acculturative stress experienced during undergraduate study abroad programs. It was designed to evaluate the impact of cognitive behavioral strategy training combined with intentional practice during mixed reality (MR) simulations on acculturative stress. Participants included a convenience sample of undergraduate nursing students enrolled in a faculty-led study abroad course. Students participated in two MR simulations within a virtual environment over back-to-back days. Simulations were written by nursing faculty experts to reproduce realistic clinical situations students may encounter while studying in Peru. The Generalized Self-Efficacy Scale, State-Trait Anxiety Inventory, and Slater-Usoh-Steed …

Signaling Mechanisms Underlying Activity-Dependent Integration Of Adult-Born Neurons In The Mouse Olfactory Bulb, Suyang Bao, Juan M Romero, Benjamin D W Belfort, Benjamin R Arenkiel

Duncan NRI Faculty and Staff Publications

Adult neurogenesis has fascinated the field of neuroscience for decades given the prospects of harnessing mechanisms that facilitate the rewiring and/or replacement of adult brain tissue. The subgranular zone of the hippocampus and the subventricular zone of the lateral ventricle are the two main areas in the brain that exhibit ongoing neurogenesis. Of these, adult-born neurons within the olfactory bulb have proven to be a powerful model for studying circuit plasticity, providing a broad and accessible avenue into neuron development, migration, and continued circuit integration within adult brain tissue. This review focuses on some of the recognized molecular and signaling …

Total Syntheses Of Hosieines A-C, Jiayang Zhang, Xu Yan, Qing-Bao Zhang, Fang Wang, Bin Yang, Yang Yang

Children’s Nutrition Research Center Staff Publications

The collective total syntheses of (±)-hosieines A-C with a cage-like tetracyclic framework have been realized, which includes the first syntheses of hosieines B-C. The key strategy of the synthesis employs a one-pot domino reaction that involves Cu-catalyzed [3+2] cycloaddition, 1,6-enone formation, and 1,6-aza-Michael addition forming the 5/6/6-aza-tricyclic skeleton. Other salient synthetic tactics comprise a challenging double bond migration and a 1,4-aza-Michael addition reaction to afford the tetracyclic framework.

Lac-Phe Mediates The Effects Of Metformin On Food Intake And Body Weight, Shuke Xiao, Veronica L Li, Xuchao Lyu, Xudong Chen, Wei Wei, Fahim Abbasi, Joshua W Knowles, Alan Sheng-Hwa Tung, Shuliang Deng, Gaurav Tiwari, Xu Shi, Shuning Zheng, Laurie Farrell, Zsu-Zsu Chen, Kent D Taylor, Xiuqing Guo, Mark O Goodarzi, Alexis C Wood, Yii-Der Ida Chen, Leslie A Lange, Stephen S Rich, Jerome I Rotter, Clary B Clish, Usman A Tahir, Robert E Gerszten, Mark D Benson, Jonathan Z Long

Children’s Nutrition Research Center Staff Publications

Metformin is a widely prescribed anti-diabetic medicine that also reduces body weight. There is ongoing debate about the mechanisms that mediate metformin’s effects on energy balance. Here, we show that metformin is a powerful pharmacological inducer of the anorexigenic metabolite N-lactoyl-phenylalanine (Lac-Phe) in cells, in mice and two independent human cohorts. Metformin drives Lac-Phe biosynthesis through the inhibition of complex I, increased glycolytic flux and intracellular lactate mass action. Intestinal epithelial CNDP2+ cells, not macrophages, are the principal in vivo source of basal and metformin-inducible Lac-Phe. Genetic ablation of Lac-Phe biosynthesis in male mice renders animals resistant to the …

Governmental Affairs Update: Dental Medicaid, Neema Katibai Jd

The Journal of the Michigan Dental Association

The MDA spearheads an initiative to enhance Medicaid anesthesia services reimbursement, aiming to address the disparity between current rates and commercial standards. Despite recent improvements in Medicaid dental benefits, access to care remains hindered by low anesthesia reimbursement rates. The MDA advocates for a substantial investment to increase reimbursement to 85% of commercial rates, garnering support from various medical associations. This collaborative effort marks a significant stride towards achieving equitable Medicaid reimbursement. Grassroots advocacy is pivotal in influencing state budget decisions, urging constituents to engage with legislators via MDA text alerts.

Workers' Rights Front And Center, Lance Plunkett Jd, Llm

The New York State Dental Journal

New York City takes lead in codifying employee rights and employer obligations.

The Effect Of Dental Insurance Coverage And Economic Fluctuations On Oral Health Outcomes In The United States, Laura Singletary

Senior Theses

Proper oral health is imperative to overall health, but obstacles often persist in

receiving proper oral health care. Lack of dental insurance coverage and economic recessions are two main factors contributing to oral health outcomes. Extended time without cleanings or addressing current oral health concerns exacerbates oral health problems into more costly procedures for the patient that are conveniently not covered by many insurance plans. This thesis investigates the oral health outcomes associated with periods following economic downturns, specifically citing the time of the Great Recession from 2007-2009.

The Health Effects Of Chocolate: A Literature Review, Erika A. Pierce

Senior Theses

Chocolate has been a part of the human diet for centuries, but while it was once considered a healthy food, it is now seen as a dessert and unhealthy treat. It is known that chocolate contains polyphenols, flavonoids, and minerals that can affect body functioning. To determine the extent to which chocolate plays a role in health, a literature review was performed by searching the PubMed, CINAHL, and Web of Science databases for peer-reviewed articles published between 2004 and 2024. Of the 14 included studies, the health effects of chocolate fell into three overarching categories: neurological effects, including mental health, …

Decoding Implant-Related Sickness: Unraveling The Complexities Of Breast Implant Illness, Madison M. Stewart

Senior Theses

This thesis investigates the phenomenon of breast implant illness (BII), examining its potential correlation with individual factors such as obesity and poor lifestyle habits. BII, characterized by nonspecific symptoms, is often self-diagnosed by patients influenced by social media and internet sources, leading to requests for implant removal. Conducting a comprehensive meta-analysis, the study scrutinizes existing literature to evaluate the association between BII, obesity, and lifestyle choices. Employing inclusion criteria, peer-reviewed publications are analyzed through systematic review methodology to offer insights into the interplay between BII and adiposity, exploring inflammatory mechanisms and patient behaviors like exercise and smoking. The research aims …

Music As A Coping Mechanism: Clinical Implications Of How College Students Utilize Music To Cope With Anxiety, Depression, And Daily Stressors, Karly Pikel

Senior Theses

Many college students face stress, anxiety, and/or depression in their daily lives which they cope with in their own ways. Listening to music or playing an instrument are particularly powerful forms of coping that can have a plethora of positive effects on an individual. The purpose of this study was to conduct a survey amongst the University of South Carolina student body to determine how they utilize music to cope in their daily lives. Of 847 respondents, almost all of them reported experiencing some extent of anxiety and/or stress and listening to music to help them cope. Respondents agreed that …

"Fueling For A Healthy Life:" A Cooking Class For Adolescent And Young Adult Childhood Cancer Survivors, Hope Dominique

Senior Theses

Following cancer treatment, childhood cancer survivors (CCS) are at an increased risk of developing chronic diseases and face an increased risk of health-related death during adulthood. Recent literature demonstrates that modifying lifestyle factors such as nutrition can reduce the risk of late mortality in survivors, suggesting that interventions promoting a healthy lifestyle may improve quality and quantity of life for CCS. However, many adolescent and young adult (AYA) CCS do not adhere to national dietary guidelines and face both real and perceived barriers to adopting healthier eating habits while in a critical period for establishing behaviors that contribute to lifelong …

”To Be Or Not To Be – It’S Good”: Actor And Student Experiences In A Drama Club For People With Aphasia, Jade K. Hannan

Senior Theses

Individuals with aphasia, a disorder caused by damage to the brain’s language network, confront a variety of social and emotional struggles. While leaving their cognition largely intact, aphasia tremendously impacts a person’s ability to communicate confidently, fracturing their social network and contributing to feelings of loneliness and frustration. To address this persistent need in the chronic aphasia population, the Play on Words drama club at the University of South Carolina provides a forum for people with aphasia (PWA) to engage in dramatic exercises focused on non-verbal communication of emotions, ideas, and stories, culminating the production of an original devised play. …

Elucidating The Role Of Protease-Activated Receptor 2 In Elastase-Induced Abdominal Aortic Aneurysms, John Pitstick

Senior Theses

Cardiovascular diseases (CVDs) remain the leading cause of mortality in the world despite extensive research. As a type of CVD, abdominal aortic aneurysm (AAA) represents a critical medical condition characterized by the localized dilation of the abdominal aorta. Complications from aneurysm development results in catastrophic aortic rupture, which leads to mortality more than 80% of the time. As aneurysm development is typically asymptomatic, many AAAs remain untreated until they present a serious risk of rupture. Additionally, no pharmaceutical treatment exists for AAAs, with the only option being surgical intervention. Despite advancements in diagnostic methods and surgical techniques, the pathogenesis of …

Focus Group And Survey Responses To Postural Feedback During Creative Movement Exploration, Mary C. Matthews

Senior Theses

John H. Riskind’s “appropriateness hypothesis” states that posture, positions, and gestures can be emotionally self-regulating if an individual holds a posture that is appropriate for its context. A litany of studies on power posing suggests expansive postures could increase Feelings of Power. One meta-analytic review demonstrates the “robust” significance for evidence of “power feelings, emotion, or self-esteem” due to postural feedback while cautioning researchers on the empirical invalidity of evidence for behavioral and physiological variables. A qualitative description of individuals’ experiences as they change posture, gesture, and position would direct future research on postural feedback. The current project qualitatively examines …

Exploratory Multiple Regression Analysis Of Predictive Factors On Pediatric Concussion Recovery, Jaimeen Shah

Senior Theses

This study ultimately aimed to find how different extra-clinical factors correlate with different aspects of concussion recovery. This study evaluated 8 different independent variables and their correlation to 4 different dependent variables (that are composed of 11 sub-dependent variables). It was hypothesized that these predictive variables will have a statistically significant impact on somatic, psychological, and cognitive outcomes. Additionally, it was hypothesized that the majority of these predictive factors will have the largest statistically significant impact on cognitive outcomes and that time to biological sex, age, prior concussion history, and household income (in that respective order) would have the strongest …

Promoting Empowerment Among Patients And Collaboration Between Obstetricians And Midwives During The Pregnancy And Birth Experience, Alexandra R. Mcdermott

Senior Theses

The purpose of this paper was to evaluate how obstetricians and midwives promote empowerment among patients and support effective collaboration between providers during pregnancy and childbirth. This thesis explores patient care and interprofessionalism as they relate to maternal health, addressing gaps in knowledge regarding how obstetricians and midwives practicing in or near Columbia, South Carolina view these concepts. An extensive literature review was conducted to fully understand pregnancy and childbirth across history and today, throughout the United States and beyond. Obstetrics, midwifery, and a comparison of these fields were explored thoroughly in addition to an analysis of maternal and infant …

A Comparison Of Curricula At The University Of South Carolina School Of Medicine And The Unité De Formation Et De Recherche Simone Veil And Their Impacts On Student Outcomes, Bailey Kicklighter

Senior Theses

This study examines the impact of medical school curricula on student outcomes. It does so by analyzing the current curricula at the University of South Carolina School of Medicine (USC School of Medicine) and the Unité de Formation et de Recherche Simone Veil (UFR Simone Veil). The UFR Simone Veil is a medical education program at the Université de Versailles Saint-Quentin-en-Yvelines. This research is important because it could encourage educators to examine the effectiveness of their current practices through comparison with the practices of other academic institutions. It also allows students to consider the course of study they might like …

Redesign Of Robotic Walking Training Device To Involve Zero Gravity Capabilities And Daily Activities, Chad Ballard

Mechanical Engineering Theses

Many patients struggle with disabilities that hinder their ability to walk. This project aimed to create a leg assembly capable of variable gravity so that it could be combined with a Robotic Walking Training Device, and lead to better rehabilitation options for patients. This was accomplished by deriving equations of joint torque, creating circuit diagrams for Arduino systems, modeling leg assemblies in CAD, and finally combining it to create a working small-scale prototype. The result of the prototype testing showed accurate movement on each joint, especially the ankle and knee segments, to create virtual zero gravity. In addition to this, …

The Role Of Pfkfb3 In Ampk-Activated Glut4 Translocation, Katherine Renee Bosch

Senior Honors Theses

Type 2 diabetes is a chronic, potentially deadly disease that impacts millions of Americans’ lives. Type 2 diabetes is characterized by increased blood glucose levels caused by insulin resistance. The normal insulin signaling pathway leads to glucose uptake by GLUT4 through activation of the IRS-1-PI3K-Akt pathway, as well as the insulin-independent pathway that utilizes AMPK. Additionally, PFKFB3 may play a role in insulin signaling and glucose uptake. PFKFB3 is an enzyme that plays an important role in activating PFK-1, which is a rate-limiting enzyme in glycolysis. PFKFB3 is frequently studied for its role in cancer due to its role in …

Nursing Care Regarding Social Determinants Of Health For Breastfeeding In Mothers And Infants, Natalie Jefson

Senior Honors Theses

Breastfeeding is incredibly important to the health and well-being of the mother-infant dyad. Because of this, there are both world-wide and national recommendations and guidelines for breastfeeding in the United States. Although many women choose to initiate breastfeeding, the percentage of women who continue breastfeeding for the recommended duration does not meet the Healthy People goal for the United States. Many factors influence this early breastfeeding cessation, including physical and socioeconomic barriers. Certain populations face increased barriers to reaching these goals related to social determinants of health which can and should be addressed by nurses through preventive measures and education.

Clinical Experiences Of Rn To Bscn Nursing Students In Kenyan Universities, Gladys Mbuthia, Gisela Rensburg Rensburg, Sheila Shaibu

School of Nursing & Midwifery, East Africa

Introduction and objective: Clinical learning environments play a great role in nursing training as they allow nursing students to develop their clinical skills by combining cognitive, psychomotor and affective skills. Consequently, clinical learning environments enable nursing students to bridge the theory-practice gap. Fewer studies have examined the clinical experiences of RN to BScN students in Kenya. This paper is part of analytical memo of a larger PhD study that sought to explore and describe the support needs of RN to BScN students in Kenyan universities. The paper focuses on clinical experiences of RN to BScN students.

Methods: Using a qualitative …

Adolescent Marijuana Use And The Contribution To The Development Of Schizophrenia, Jocelyn Spandikow

Psychology Student Papers and Posters

Schizophrenia is an often debilitating mental condition that has become a popular topic of psychological research in recent years. Current research examines the correlation between drug use, genetics, and environment on the development of schizophrenia. Research looks at the structure of the brain in individuals with and without schizophrenia. However, research has failed to look at the specific correlation between marijuana use in adolescent youth and the developmental impact on the brain, including in the development of schizophrenia. The legalization of many recreational drugs, including marijuana, has come to fruition in recent years. This has raised concerns over adolescent access …

Incidental Actinomycosis In A 44-Year-Old Female During Total Abdominal Hysterectomy For Abnormal Uterine Bleeding: A Case Report, Willbroad Kyejo, Allyzain Ismail, Abduel Kitua, Brenda Moshi, Gregory Ntiyakunze, Munawar Kaguta, Ally Mwanga

Internal Medicine, East Africa

Actinomycosis, a rare chronic bacterial infection caused by Actinomyces species, presents diagnostic challenges due to diverse clinical presentations. This report presents a case of peritoneal actinomycosis incidentally discovered during a total abdominal hysterectomy in a 44-year-old female with refractory abnormal uterine bleeding and a history of long-term intrauterine contraceptive device use. The patient presented with persistent abnormal uterine bleeding despite conservative management. Intraoperative findings during total abdominal hysterectomy revealed peritoneal involvement, prompting histopathological evaluation confirming actinomycosis. This case highlights diagnostic complexities associated with actinomycosis, emphasizing the significance of histopathological confirmation. Postoperative management with antibiotics demonstrated favorable outcomes, supporting their efficacy …

Acute Coronary Syndrome Patterns In The Young: Risk Factor Profile And In-Hospital Outcomes In A Tertiary Referral Hospital In Kenya, Nadeem Kassam, Mzee Ngunga, Mohamed Varwani, Miriam Msunza, Jeilan Mohamed

Internal Medicine, East Africa

Introduction: Acute coronary syndrome (ACS) accounts for coronary artery disease (CAD) –related morbidity and mortality. There has been growing concern about the rising incidence of ACS among young individuals globally both in developed and developing countries, including Sub-Saharan Africa. This group’s phenotypic characteristics; risk factors and clinical outcomes are not well described. contextual and regional studies are necessary to understand the magnitude of ACS among young Individuals and help highlight challenges and opportunities for improved ACS outcomes in the region. The study aimed to describe the demographic and clinical characteristics of young individuals hospitalized with ACS and report on in-hospital …

Transitioning From Afmrd Entrustable Professional Activities To Abfm Core Outcomes To Measure Clinical Preparedness., Bryce A Ringwald

Medical Education Articles

No abstract provided.

Shaping The Future Of Vascular Care: The Evolution Of Advanced Practice Providers (Apps)., Alexandra Moran Baird, Katherine Hays, Danielle Vlazny

Medical Education Articles

No abstract provided.

Learning To Lead: The Evolution Of A Pilot Leadership Curriculum For Gynecologic Oncology Fellows At The Ohio State University., Monica D Levine, Vincent M Wagner, Courtney J Riedinger, Wafa Khadraoui, Paulina J Haight, Molly Morton, David A Barrington, Corinne A Calo, Antonio V Castaneda, Michelle Lightfoot, Julia Chalif, Anna Gonzalez, David E Cohn

Medical Education Articles

•Leadership training is under-emphasized in traditional medical education.•An effective leadership curriculum must be dynamic and requires genuine investment from participants.•Through didactic education, self-reflection, and real-world perspective we can actively mold future leaders in gynecologic oncology.

Systemic Neutrophil Gelatinase-Associated Lipocalin Alterations In Chronic Pancreatitis: A Multicenter, Cross-Sectional Study, Kristyn Gumpper-Fedus, Kaylin Chasser, Valentina Pita-Grisanti, Molly Torok, Timothy Pfau, Thomas A Mace, Rachel M Cole, Martha A Belury, Stacey Culp, Phil A Hart, Somashekar G Krishna, Luis F Lara, Mitchell L Ramsey, William Fisher, Evan L Fogel, Chris E Forsmark, Liang Li, Stephen Pandol, Walter G Park, Jose Serrano, Stephen K Van Den Eeden, Santhi Swaroop Vege, Dhiraj Yadav, Darwin L Conwell, Zobeida Cruz-Monserrate, Consortium For The Study Of Chronic Pancreatitis, Diabetes, And Pancreatic Cancer (Cpdpc)

Faculty, Staff and Student Publications

Introduction: Chronic pancreatitis (CP) is a progressive fibroinflammatory disorder lacking therapies and biomarkers. Neutrophil gelatinase-associated lipocalin (NGAL) is a proinflammatory cytokine elevated during inflammation that binds fatty acids (FAs) such as linoleic acid. We hypothesized that systemic NGAL could serve as a biomarker for CP and, with FAs, provide insights into inflammatory and metabolic alterations.

Methods: NGAL was measured by immunoassay, and FA composition was measured by gas chromatography in plasma (n = 171) from a multicenter study, including controls (n = 50), acute and recurrent acute pancreatitis (AP/RAP) (n = 71), and CP (n = 50). Peripheral blood mononuclear …

Achieving Procedural Parity In Managing Access To Genomic And Related Health Data: A Global Survey Of Data Access Committee Members, Jonathan Lawson, Vasiliki Rahimzadeh, Jinyoung Baek, Edward S Dove

Center for Medical Ethics and Health Policy Staff Publications

Data access committees (DACs) are critical players in the data sharing ecosystem. DACs review requests for access to data held in one or more repositories and where specific constraints determine how the data may be used and by whom. Our team surveyed DAC members affiliated with genomic data repositories worldwide to understand standard processes and procedures, operational metrics, bottlenecks, and efficiencies, as well as their perspectives on possible improvements to quality review. We found that DAC operations and systemic issues were common across repositories globally. In general, DAC members endeavored to achieve an appropriate balance of review efficiency, quality, and …

2024 Spring Vol. 41 No. 1, Alumni Affairs School Of Medicine

Medicinews

No abstract provided.