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Articles 5611 - 5640 of 324920
Full-Text Articles in Medicine and Health Sciences
Family Perspectives: A Qualitative Examination Of College Athlete Suicide During The Spring 2022 Semester, Elaine M. Anton-Lotruglio, Sophia M. Burke, Kimberly H. Mcmanama O'Brien
Family Perspectives: A Qualitative Examination Of College Athlete Suicide During The Spring 2022 Semester, Elaine M. Anton-Lotruglio, Sophia M. Burke, Kimberly H. Mcmanama O'Brien
Journal of Issues in Intercollegiate Athletics
Objective: Suicide among college athletes remains largely underexplored despite rising rates. This qualitative study aimed to explore family members' perspectives on why their loved ones died by suicide. Participants: The study included family members (N=10) of three college athletes who died by suicide in the spring 2022 semester. Methods: Semi-structured interviews were conducted between March and July 2024. ATLAS.ti and Braun and Clarke's thematic analysis were employed to analyze the data and identify themes. Results: The data revealed three primary themes: factors contributing to the suicide crisis, presence of a suicide crisis, and university crisis response. The themes suggested a …
Volume 12 Full Text, Bjur Staff
Volume 12 Full Text, Bjur Staff
Butler Journal of Undergraduate Research
No abstract provided.
Exploring Gender As An Analytical Framework In The 2018-2019 Revolution And Ongoing Civil War: The Role Of Gendered Violence And Sudanese Women's Resistance, Ami John
Butler Journal of Undergraduate Research
This paper will interrogate the intersection of gender, war, and political upheaval within Sudan while focusing on the role of women in both the 2019 resistance and the ongoing conflict and revolution. By the end of 2018, mass protests had called for the ousting of Omar al-Bashir, the long-standing Sudanese president. This event set off a chain reaction which led to events that fueled the long-standing rivalry between the two militant groups that were active in Sudan, the Rapid Support Forces (RSF) and the Sudanese Armed Forces (SAF). The tension caused by this rivalry created unforeseen circumstances for the local …
Front Matter And Table Of Contents, Bjur Staff
Front Matter And Table Of Contents, Bjur Staff
Butler Journal of Undergraduate Research
No abstract provided.
Evaluating The Impact Of Evidence-Based Education On The Utilization Of Preoperative Gastric Ultrasound For Patients On Glp-1 Agonists, Rachel K. Gibbons, Wesley Johnson, Rachel Cartillar
Evaluating The Impact Of Evidence-Based Education On The Utilization Of Preoperative Gastric Ultrasound For Patients On Glp-1 Agonists, Rachel K. Gibbons, Wesley Johnson, Rachel Cartillar
Create@State
Abstract
Patients taking glucagon-like peptide-1 (GLP-1) receptor agonists have a 30.5% higher prevalence of retained gastric contents at the time of surgery despite being held according to ASA and AANA recommendations, highlighting the need for enhanced preoperative assessment to reduce aspiration risk (Sen et al., 2024; Willson et al., 2024). Although an effective, noninvasive tool for assessing gastric contents and reducing the risk of pulmonary aspiration, gastric ultrasound remains underutilized in anesthesia practice (Pan et al., 2024). This evidence-based project evaluated whether an educational intervention could improve anesthesia providers’ knowledge, attitudes, and readiness to adopt point-of-care gastric ultrasound (POC-GUS) into …
Evaluation Of The Compliance Of Ultra-Low Dose Drugs Available In Local Iraqi Markets With Regulatory Weight Variation Test, Yousif K. Younis
Evaluation Of The Compliance Of Ultra-Low Dose Drugs Available In Local Iraqi Markets With Regulatory Weight Variation Test, Yousif K. Younis
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Mixing and formulation of drugs with very low dose is a brutal challenge to formulators sometimes due to all kinds of difficulties like segregation, content uniformity and physicochemical stability issues. A careful consideration of all related factors is essential during manufacturing of very low dose drug products. The aim of this study is to evaluate the quality control of ultra-low dose drugs of different companies available in local Iraqi and their compliance with regulatory weight variation test. Quantitative analysis conducted to five drugs using weight variation technique with 20 randomly selected tablets for each drug. All of these drugs passed …
A Comparative Study Examining The Effects Of Nifedipine And Minoxidil On Stimulating Hair Growth Using A Mouse Model, Nihad Hussein Ahmed, Rabei Abdullah Salih, Shereen M. Mekkey
A Comparative Study Examining The Effects Of Nifedipine And Minoxidil On Stimulating Hair Growth Using A Mouse Model, Nihad Hussein Ahmed, Rabei Abdullah Salih, Shereen M. Mekkey
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Hair loss is a common human scalp condition caused by chemotherapy, chronic diseases, and aging. Currently, it is estimated that approximately 50% of males and 15–30% of females experience hair loss issues. Minoxidil is considered a preferred treatment for hair loss in men and women. Nifedipine is effective in improving blood circulation and blood supply via its vasodilator action. To compare nifedipine and minoxidil in terms of their effect on stimulating hair growth using a mouse model. Fifteen female albino mice, aged 8 to 10 weeks, were randomly assigned to three groups of five mice each, all with shaved dorsal …
Buccal Films As An Emerging Drug Delivery System: A Comprehensive Review, Syed Faizan Syed Nizamuddin, Nishan N. Bobade, Vikrant P. Wankhade, Sandeep C. Atram, Shrikant D. Pande, Nakul S. Dhore, Shraddha P. Malpani, Ashwin A. Pahurkar
Buccal Films As An Emerging Drug Delivery System: A Comprehensive Review, Syed Faizan Syed Nizamuddin, Nishan N. Bobade, Vikrant P. Wankhade, Sandeep C. Atram, Shrikant D. Pande, Nakul S. Dhore, Shraddha P. Malpani, Ashwin A. Pahurkar
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Oral administration through the digestive tract is still the most common means by which drugs are given, as it is simple and cheap. However, it has some biopharmaceutical limitations in general, such as varying gastrointestinal conditions, enzymatic degradation, and extensive hepatic first-pass metabolism, which decrease drug stability and bioavailability To address these challenges, drug delivery through the oral mucosa (OMDD) has emerged as a potential non-invasive option. The buccal mucosa is well supplied with blood, provides a relatively mild environment, and avoids hepatic first-pass metabolism, thereby resulting in a faster onset of action and improved bioavailability. Mucoadhesive buccal films have …
Ethnopharmacology, Phytochemistry, And Pharmacological Potential Of Philenoptera Laxiflora: An Emerging African Medicinal Plant For Drug Discovery, Albashir Tahir
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Medicinal plants remain an important source of therapeutic agents and play a significant role in modern drug discovery. Philenoptera laxiflora (Fabaceae) is a tropical African plant widely used in traditional medicine, but the scientific evidence supporting its therapeutic potential remains fragmented. This review aims to comprehensively summarize the current knowledge on the ethnomedicinal uses, phytochemical composition, pharmacological activities, and toxicological profile of P. laxiflora, while highlighting research gaps and future directions for drug discovery. A comprehensive literature search was conducted using electronic scientific databases, including PubMed, Google Scholar, Scopus, Web of Science, and ScienceDirect. Relevant publications on the ethnobotany, …
Prevalence Of Medication Prescription Patterns For Iraqi Outpatients Visiting Otolaryngology Clinics, Mirna. K. Faiq
Prevalence Of Medication Prescription Patterns For Iraqi Outpatients Visiting Otolaryngology Clinics, Mirna. K. Faiq
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Objectives: To assess the prevalence of drug use patterns among ENT outpatient settings in Kirkuk, Iraq. Methods: This retrospective observational study was conducted in Kirkuk, Iraq, involving the collection of data from the e-Prescribing system and the review of written prescriptions, including 582 outpatient records from ENT clinics, from January 2024 to December 2024. Results: Most patients were below 20yr age (18.73%), with a male predominance (57%). Ear-related complaints like otitis media were the most frequent (35.22%). The average number of drugs per prescription was 2.82. The percentage of prescriptions in which an antibiotic was prescribed was 84.7%. The percentage …
Preparation And In-Vitro Evaluation Of Tizanidine Flash Oral Dispersible Tablet, Ahmed Yousif Fadhel, Yousif K. Younis
Preparation And In-Vitro Evaluation Of Tizanidine Flash Oral Dispersible Tablet, Ahmed Yousif Fadhel, Yousif K. Younis
Al-Mustaqbal Journal of Pharmaceutical and Medical Sciences
Background: Oral administration is the most common and preferred route for drug delivery. Oral dispersible tablets (ODTs) are solid dosage forms that disintegrate into saliva without the need for water. Tizanidine is a centrally acting muscle relaxant used to manage spasticity from spinal or brain injuries. Preparing it as a flash (ODT) tablet may enhance patient compliance and potentially improve bioavailability by bypassing part of the first-pass metabolism. Methods: Six formulations of tizanidine flash tablets were developed using varying concentrations of mannitol (bulk-forming agent), glycine (to aid tablet collapse), and gelatin (matrix-forming agent). The formulations were evaluated for weight variation, …
Bioactive Constituents And Pharmacological Activities Of Curcuma Zedoaria: A Mini-Review, Abdulmutalib Allaq, Muneer M. Saleh Mohammed Saleh Alsayadi, Mustapha Salihu, Hasan M. Agha, Amena Hassan Hassan Gheeth, Fatimah Salim, Norrizah Jaafar Jaafar Sidik
Bioactive Constituents And Pharmacological Activities Of Curcuma Zedoaria: A Mini-Review, Abdulmutalib Allaq, Muneer M. Saleh Mohammed Saleh Alsayadi, Mustapha Salihu, Hasan M. Agha, Amena Hassan Hassan Gheeth, Fatimah Salim, Norrizah Jaafar Jaafar Sidik
AUIQ Complementary Biological System
Curcuma zedoaria Rosc. (white turmeric) is a rhizomatous medicinal plant in the Zingiberaceae family, widely used in traditional Asian medicine. In recent years, increasing scientific attention has focused on its diverse pharmacological properties and bioactive constituents. This mini review summarises current knowledge of the phytochemical composition and biological activities of C. zedoaria, with particular emphasis on its antimicrobial, antioxidant, anti-inflammatory, and anticancer effects. Phytochemical investigations using analytical techniques such as GC–MS and HPLC have revealed the presence of numerous bioactive compounds, including sesquiterpenes (example, germacrone, curzerenone, and curdione) and curcuminoids, which contribute to its therapeutic potential. Experimental studies demonstrate …
Evaluation Of Circulating Hpg80, Ca15-3, Estrogen And Progesterone As Biomarkers In Breast Cancer Patients, Safa Khaldoon, Emad Yousif, Khawla A. Kasar, Muna Bufaroosha, Rahimi Yusop
Evaluation Of Circulating Hpg80, Ca15-3, Estrogen And Progesterone As Biomarkers In Breast Cancer Patients, Safa Khaldoon, Emad Yousif, Khawla A. Kasar, Muna Bufaroosha, Rahimi Yusop
AUIQ Complementary Biological System
It is very important to find reliable biomarkers for early detection and monitoring of treatment response because breast cancer is still one of the most common cancers in women around the world. The goal of this study was to find out how clinically important different biochemical markers are in Iraqi women with breast cancer. Some of these signs are progesterone (PG), oestrogen (E2), cancer antigen 15-3 (CA15-3), and circulating progastrin (hPG80). There were 100 women in this study, and they were all between the ages of 20 and 70. There were three groups of people who took part: a healthy …
Synergistic Endocytic Receptor Ligand Receptor Protein 2 In T2dm, Wafaa Raji Alfatlawi
Synergistic Endocytic Receptor Ligand Receptor Protein 2 In T2dm, Wafaa Raji Alfatlawi
AUIQ Complementary Biological System
Purpose: The glycoprotein molecule known as megalin is present on the proximal renal tubular epithelial cells. With an emphasis on megalin and cubilin levels in T2DM and IR patients, an area that obviously needs more research, this study attempts to give an outline of current knowledge of megalin function in relation to vitamin D and its metabolite (vitamin D receptor and vitamin D binding protein). Materials and Methods: This was a case control comparative study conducted at a endocrine and diabetes center in AL-Imamain Kadumain teaching hospital in Baghdad-Iraq. Study subjects were divided into three groups: 25 with T2DM with …
Optimizing Glycemic Control In Type Ii Diabetes: Continuous Glucose Monitoring : A Scoping Review, Sarah Poe, Bsn, Rn, Bailey Li, Bsn, Rn, Tracy Mcclinton, Dnp, Aprn, Ag-Acnp-Bc, Hget-C, Ebp-C
Optimizing Glycemic Control In Type Ii Diabetes: Continuous Glucose Monitoring : A Scoping Review, Sarah Poe, Bsn, Rn, Bailey Li, Bsn, Rn, Tracy Mcclinton, Dnp, Aprn, Ag-Acnp-Bc, Hget-C, Ebp-C
Doctor of Nursing Practice Projects
Purpose/Background
Individuals with Type II diabetes mellitus (T2DM) experience increased risk of cardiovascular disease and higher mortality rates relative to non-diabetic populations. Continuous glucose monitoring (CGM) enables more precise analysis of glucose patterns and trends compared to conventional self-monitoring of blood glucose (SMBG). CGM provides frequent measurements and generate meaningful metrics, such as time in range (TIR), time above range (TAR), and time below range (TBR), allowing evaluation of glucose stability and variability. Despite these advantages, evidence comparing CGM and SMBG remains inconsistent. This scoping review aims to evaluate how CGM compares with SMBG across reported outcomes, including TIR, TAR, …
Mindful Tea Drinking As A Low-Cost Sensory Intervention For Reducing Stress In College Students, David Gabel
Mindful Tea Drinking As A Low-Cost Sensory Intervention For Reducing Stress In College Students, David Gabel
Honors Projects
The proposed study would investigate the effects of a tea-based sensory mindfulness exercise on stress in college aged participants. Participants would listen to a mindful tea exercise and a non-mindful tea exercise after a mild stress-inducing Stroop test. For both conditions, the participants would report their current state of distress on the Subjective Units of Distress Scale (SUDS) before and after each tea exercise and their heart rate variability (HRV) would be measured during each segment of the experiment.
Descriptive statistics and a paired samples t-test would be used to compare the mindful tea condition with the non-mindful condition following …
Lateral Habenula And Dorsal Raphe Neurons Signal Value Computations In Multi-Attribute Decision-Making, Yang-Yang Feng
Lateral Habenula And Dorsal Raphe Neurons Signal Value Computations In Multi-Attribute Decision-Making, Yang-Yang Feng
McKelvey School of Engineering Graduate Student Theses & Dissertations
Decision-making is a fundamental part of adaptive behavior and can be compromised in psychiatric illness. Humans and animals are continuously presented with objects and opportunities as options to decide between. One challenge is that these options may independently vary along multiple dimensions or attributes that we care about. This can include attributes of physical reward, such as amount, delay, or uncertainty. When these attributes are present, the possibility of an abstract, cognitive reward, advance information to resolve uncertainty, may also motivate our decisions. It is unclear how the brain makes these subjective decisions, trading off between these multiple attributes based …
Evaluating The Interrater Reliability For The Intern Selection Process Done At Providence Medical Group Psychology Training Program, Vanoosheh Ferdousian, M.A., Teresa Davigo, Luke Dowling
Evaluating The Interrater Reliability For The Intern Selection Process Done At Providence Medical Group Psychology Training Program, Vanoosheh Ferdousian, M.A., Teresa Davigo, Luke Dowling
Books, Presentations, Posters, Etc.
Interrater reliability (IRR) is an important component of evaluation processes that involve subjective judgments, as it reflects the degree of consistency among multiple raters. In training and hiring contexts, establishing adequate IRR helps ensure that applicant evaluations are fair, systematic, and minimally influenced by individual bias. The present program evaluation examines the interrater reliability of the intern selection process at the Providence Medical Group Psychology Training Program. Specifically, this project evaluates the consistency of raters’ scores assigned to internship applicants using the program’s standardized application rating forms. Numerical ratings from multiple reviewers were collected for each applicant and analyzed using …
The Right Time For A Synapse To Change: Windows And Mechanisms Of Multiday Training Trials, Rong-Yu Liu, Yili Zhang, Roberta Calvo, Paul Smolen, John H Byrne
The Right Time For A Synapse To Change: Windows And Mechanisms Of Multiday Training Trials, Rong-Yu Liu, Yili Zhang, Roberta Calvo, Paul Smolen, John H Byrne
Faculty, Staff and Student Publications
Although learning over multiple days is more effective than a single day of training, the underlying cellular mechanisms of repeated training trials remain poorly understood. With a combination of empirical and computational approaches, we determined a critical time window for a second stimulus block of a multiday training protocol to augment long-term synaptic facilitation (LTF) of the Aplysia sensorimotor synapse and long-term enhancement of neuronal excitability (LTEE), two cellular correlates of learning and memory. A second stimulus block delivered 24 h after the first block significantly enhanced LTF and LTEE, but was without effect at 18 or 32 h. This …
Beyond The Negative Serologies: A Case Of Fulminant Vasculitis, Multiorgan Dysfunction, And An Uncharacteristic Infection, Guo Hui (Greyson) Gan, Do
Beyond The Negative Serologies: A Case Of Fulminant Vasculitis, Multiorgan Dysfunction, And An Uncharacteristic Infection, Guo Hui (Greyson) Gan, Do
Books, Presentations, Posters, Etc.
Case Presentation: 70-year-old male presented with one week of fever and a painful right lower extremity purpuric rash that rapidly evolved into fullthickness desquamation and necrosis. Concurrent multiorgan dysfunction: respiratory failure, renal failure with nephritic proteinuria, and severe thrombocytopenia refractory to high dose steroids. Extensive serologic workup for viral, autoimmune, vascular, and hematologic etiologies were pan-negative, including serum cryoglobulins twice repeated (QR code for table of workup). A PET scan for a broad evaluation found a hypermetabolic right inguinal lymph node. Discussion: Unique features of this case: His hematologic workup was convincingly negative in setting of having type 1 CryoGN. …
Enhancing Well-Being In Long Term Care: A Lifestyle-Redesign-Based Program For Older Adults, Rachel L. Hajek
Enhancing Well-Being In Long Term Care: A Lifestyle-Redesign-Based Program For Older Adults, Rachel L. Hajek
Occupational Therapy Capstone Presentations
This project focused on the development and implementation of a Lifestyle Redesign®-based program to improve well-being and quality of life among older adults living in a skilled nursing facility. The program emphasized engagement in meaningful, client-centered activities tailored to the residents’ interests and values. Ten participants from two long-term care neighborhoods completed a five-week program consisting of ten wellness sessions. Sessions were designed to promote emotional, physical, and social engagement while incorporating participants’ personal values, including spiritual elements. Outcomes were measured using pre- and post-assessments of perceived well-being and engagement. Results indicated improvements in overall well-being, increased social …
Perceptions Of Rural Large Animal Owners On Cost And Distance As Barriers To Veterinary Medicine, Alyssa Dalleske
Perceptions Of Rural Large Animal Owners On Cost And Distance As Barriers To Veterinary Medicine, Alyssa Dalleske
Honors College Theses
Access to veterinary care remains a significant issue in rural communities due to financial, geographic, and access barriers. Limited access to veterinary care can have an impact on animal welfare and an economic impact for producers. This study aimed to assess factors influencing access to veterinary services, including cost, distance to clinics, perceived value of care, and availability of mobile veterinary professionals. The survey was distributed to rural large animal owners using social media, and gained 20 participants. It collected data on perceived barriers within their communities. The survey results indicated that cost of care and distance to veterinary clinics …
Success Or Setback: A Literature Review Of The Association Between Youth Athlete Sport Specialization And Injury Incidence From Adolescence To Adulthood., Kelis Adams
Honors College Theses
For a multitude of reasons, in the United States, present day society is a persistent witness and contributor to the adultification and professionalization of children alongside the activities they engage in. Single-sport specialization in youth sports is one of our most clear and poignant instances of the existence of this subcurrent. But, in recent years, following the uptick in single-sport specialization among youth athletes there has also been a marked increase in sports medicine professionals cautioning athletes and their families of premature commitment to a sole sport due to concerns of physical health risks. As sport typically involves forceful and …
Evaluating The Screening And Referral Process For The Use Of Phq-9 Screening Tool In Middle-School Aged Students: A Scoping Review, Kaythi Soe, Msn, Pmhnp-Bc, Fnp-Bc, Margaret Harvey Phd, Acnp-Bc, Fhrs, Sharon Little Dnp, Fnp-Bc
Evaluating The Screening And Referral Process For The Use Of Phq-9 Screening Tool In Middle-School Aged Students: A Scoping Review, Kaythi Soe, Msn, Pmhnp-Bc, Fnp-Bc, Margaret Harvey Phd, Acnp-Bc, Fhrs, Sharon Little Dnp, Fnp-Bc
Doctor of Nursing Practice Projects
No abstract provided.
Parent Well-Being In Early Intervention: The Case For Assessing Parental Stress, Karla Michelle Chaff
Parent Well-Being In Early Intervention: The Case For Assessing Parental Stress, Karla Michelle Chaff
Post-Professional Occupational Therapy Doctorate - Innovations in OT Symposium: Transforming Possibilities into Practice
Importance:
Research shows that parental stress negatively impacts child developmental outcomes, indicating caregiver well-being can directly influence intervention responses. Parental stress is a well-documented barrier to effective early intervention that remains unmeasured.
Objective:
This quality improvement project aims to assess the potential for adoption of a parent stress measure into family assessment to ensure caregiver well-being is systematically identified, documented, and addressed.
Design:
A feasibility project design was used to evaluate relevance, usability, barriers, and facilitators to introducing a standardized stress measure in practice.
Setting:
The project is based in an early intervention program.
Participants:
Key stakeholders were recruited from …
Enhancing Gestational Diabetes Screening, Sataj Johnson, Daniel Ruegg
Enhancing Gestational Diabetes Screening, Sataj Johnson, Daniel Ruegg
Books, Presentations, Posters, Etc.
Background: Gestational diabetes mellitus (GDM) screening is recommended between 24–28 weeks of gestation to allow timely diagnosis and treatment and reduce adverse maternal and neonatal outcomes. The two-step glucose tolerance testing method is supported by ACOG, though completion can be delayed due to the need for multiple tests. In 2024 at Providence Milwaukie Family Medicine Clinic, incomplete GDM screening occurred in 23.1% of patients, and incomplete two-step screening occurred in 33.3%, with an average completion time of 12 days. Objective: To increase completion rates of two-step GDM screening and reduce time between abnormal 1-hour and diagnostic 3-hour glucose tolerance tests …
Acquired Amegakaryocytic Thrombocytopenia And Pure Red Cell Aplasia As Initial Presentation Of Thymoma, Nidhi Patel, Md, Natasha Edwin, Md
Acquired Amegakaryocytic Thrombocytopenia And Pure Red Cell Aplasia As Initial Presentation Of Thymoma, Nidhi Patel, Md, Natasha Edwin, Md
Books, Presentations, Posters, Etc.
Introduction: Pure Red Cell Aplasia (PRCA) is a common feature of thymomas, but it rarely presents with acquired amegakaryocytic thrombocytopenia (AAMT). Here, we present a case of a 59-year-old male with fatigue found to have severe anemia and thrombocytopenia, who was eventually diagnosed with a thymoma Case Presentation: Found to have Hg of 6.1 g/dL and platelet count of 33 k/uL; Reticulocyte count was 0.0068. CT chest showed an anterior mediastinal mass measuring 4.5 x 6.6 cm. Mass biopsy showed thymoma. Bone marrow biopsy showed 50% cellularity with absence of erythroid and megakaryocyte precursors compatible with AAMT and PRCA. At …
Addition Of Gitr Agonist To A Dark Matter Cancer Vaccine And Anti-Pd-1 Increases Regulatory T Cell Numbers Without Appearing To Impact Therapeutic Efficacy, Rom S. Leidner1, Guo Hui Gan1, Christopher C. Paustian, Shawn M. Jensen
Addition Of Gitr Agonist To A Dark Matter Cancer Vaccine And Anti-Pd-1 Increases Regulatory T Cell Numbers Without Appearing To Impact Therapeutic Efficacy, Rom S. Leidner1, Guo Hui Gan1, Christopher C. Paustian, Shawn M. Jensen
Books, Presentations, Posters, Etc.
Background: DPV-001 is an off-the-shelf cancer vaccine containing tumor associated proteins commonly overexpressed in adenocarcinoma and squamous cell carcinoma. It is enriched for short-lived proteins (SLiPs) and defective ribosomal products (DRiPs), including both canonical and non-canonical (or “dark matter”) antigens —comprising over 100 identified non-canonical microproteins. These antigens are delivered in spectrin-coated microvesicles that contain 5 TLR/ NOD agonists and 15DAMPs/molecular chaperones, and target CLEC9A+ conventional dendritic cells (cDCs). Preclinical models showed enhanced antitumor responses when the murine analog of DPV-001 (DRibbles) was combined with co -stimulatory agonists. Additional studies showed enhanced antitumor responses when co-stimulatory agonists were combined with …
Acute Pancreatitis Outcomes In Native Americans In Northern Arizona, Jin Yun Do1, Afsheen Moshtaghi Do2, Hamza Khan, Md2, Hady Shahbaz Bs2, Yoshinobu Koguchi, Tarsem L. Moudgil, Noah D. Simons, Venkatesh Rajamanickam
Acute Pancreatitis Outcomes In Native Americans In Northern Arizona, Jin Yun Do1, Afsheen Moshtaghi Do2, Hamza Khan, Md2, Hady Shahbaz Bs2, Yoshinobu Koguchi, Tarsem L. Moudgil, Noah D. Simons, Venkatesh Rajamanickam
Books, Presentations, Posters, Etc.
Background and Aims: Prior studies have shown the impact of racial and ethnic disparities in outcomes of acute pancreatitis (AP). Data remains sparse for Native American populations, who may be uniquely affected by socioeconomic and geographic factors. This retrospective study aimed to evaluate the disproportionate outcomes of AP in Native Americans compared to the general population in Northern Arizona. Methods: A retrospective cohort study of hospitalized patients with AP at two community hospitals in Northern Arizona. A total of 1,113 patients between Jan and Aug 2024 were included, comprising 413 Native American patients and 700 patients of other racial backgrounds. …
Ceftriaxone-Induced Thrombocytopenia: An Atypical Presentation Of A Commonly Used Antibiotic, Matthew Moritz, Omar Pandhair
Ceftriaxone-Induced Thrombocytopenia: An Atypical Presentation Of A Commonly Used Antibiotic, Matthew Moritz, Omar Pandhair
Books, Presentations, Posters, Etc.
INTRODUCTION: Drug-induced thrombocytopenia (DITP) is rare and impacts roughly ten persons per million people annually (1). Over one-hundred medications have been identified as possible offenders, with immune response occurring within one to two weeks of drug exposure (2). Here we present a case of ceftriaxone as cause of DITP, an extremely rare complication of a commonly used antibiotic. CASE PRESENTATION: A fifty-year-old male with diabetes and depression initially presented after attempted suicide by hanging. He was intubated in the field and admitted directly to the intensive care unit (ICU). He remained in the ICU due to persistent encephalopathy which was …