Medicine and Health Sciences Commons^™

The Significance Of Palliative Care Education And Areas For Improvement, Lindsey Bunday

Honors Projects

Palliative care is vital in prioritizing quality of life for patients with serious illnesses. Such care is crucial to help patients understand their prognosis, address needs, and meet goals of care. However, physician shortages, improper utilization, and non-standardized medical curriculum amplify the gaps in care and demonstrate significant room for improvement. Innovative curriculum and opportunities for knowledge advancement can refine education and improve patient care.

Deprescribing Proton Pump Inhibitors In A Rural Health Clinic, Jason Thomas Barney

Doctoral Dissertations & Projects

Background: Proton pump inhibitors (PPIs) have been extensively prescribed for gastrointestinal pathologies, contributing to $14 billion in annual expenditure in the United States alone. Inappropriate PPI prescriptions, affecting 48% of adults, raise concerns about prolonged usage and associated health risks. Addressing these issues is vital, considering the significant impact of PPIs on patient health and healthcare costs.

Local Problem: A Midwestern clinic grapples with inappropriate and unnecessary PPI use among patients. In response, a comprehensive deprescribing intervention combining a provider algorithm with patient education was implemented to reduce PPI usage that was medically unnecessary.

Methods: A literature …

Comparison Of Perceived Stress In First-Year Pre-Med Students And First-Year Medical Students At Usd, Maggie Derner

Honors Thesis

Stress can be caused by many factors, including money, relationships, promotions, grades, and responsibilities. In college, these stressors can be exacerbated. This research dives into stress in both undergraduate students as well as medical students. Previous literature has indicated that high levels of stress are present in students, and it is likely to have negative effects on the students, whether that is their mental or physical well-being. Schools have put interventions in place to help combat the stress levels present in their students. At the University of South Dakota (USD) and USD Sanford School of Medicine (USD SSOM), perceived stress …

Bridging The Gap: Strategies For Enhancing Wic Participation Rates In South Dakota, Melissa K. Wyum

Honors Thesis

The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is a national program administered by the USDA to State agencies for low-income women and nutritionally at-risk infants and children. South Dakota WIC provides services related to breastfeeding, healthcare referrals, and accessibility/knowledge of nutritious foods. Successes of WIC include improved birth outcomes, decreased healthcare costs, regular immunization rates, establishment of a primary care provider, and improved nutrition status. Although WIC has shown positive health outcomes for mothers and children, the relationship between the barriers of WIC access and resulting health outcomes in South Dakota is unknown. According to the …

A Fair Share: Effects Of Disparity, Allocation Strategy, And System Justification On Perceptions Of Policy Support In The Education Domain, David Igliozzi, Yael Granot, Victor Ottati

Psychology: Faculty Publications

Utilizing experimental methods across a pilot and two studies, we explore and contrastt he relationship between system-justifying attitudes and fairness perceptions of and support for redistributive policies based on theoretical accounts of distributive justice, highlighting three allocation strategies: equality, equity and need. We began our investigation with a test across multiple policy domains (e.g., health care, education, employment) to examine broad associations between system justification and policy support. Then, we chose one specific domain – education – to narrow our focus on and designed two experimental studies to test more complex models of the interaction between system justification and the …

Robust Capital Cost Optimization Of Generation And Multitimescale Storage Requirements For A 100% Renewable Australian Electricity Grid, Raheel A Shaikh, David J Vowles, Alex Dinovitser, Andrew Allison, Derek Abbott

Faculty, Staff and Student Publications

Transitioning from a fossil-fuel-dependent economy to one based on renewable energy requires significant investment and technological advancement. While wind and solar technologies provide lower cost electricity, enhanced energy storage and transmission infrastructure come at a cost for managing renewable intermittency. Energy storage systems vary in characteristics and costs, and future grids will incorporate multiple technologies, yet the optimal combination of storage technologies and the role of interconnectors in alleviating storage needs are not widely explored. This study focuses on optimal generation-storage capacity requirements to elucidate associated investments. We propose a multitimescale storage solution consisting of three storage categories and an …

Evaluation Of Dietary Probiotic Supplements On Methamphetamine-Induced Impulsive Action In Rats Maintained On A Differential Reinforcement Of Low Rate Schedule, Kaitlyn Steck

Masters Theses

Substance Use Disorder (SUD) is a chronic, debilitating condition often comorbid with anxiety and depression. Both SUD and affective disorders are characterized by cognitive dysfunction, including impaired decision-making and impulsivity. A mounting body of research implicates gut microbiome alterations as a contributing factor to the pathophysiology of affective disorders. No published studies have assessed behavioral effects of dietary interventions targeting psychostimulant-induced gut microbiome changes. The present study utilized a differential reinforcement of low rate responding schedule (DRL 18 s) as a behavioral index of drug-induced impulsive action to determine if a dietary probiotic supplement alters the behavioral effects of (+)-methamphetamine …

Peripheral Artery Disease Causes Consistent Gait Irregularities Regardless Of The Location Of Leg Claudication Pain, Hafizur Rahman, Todd Leutzinger, Mahdi Hassan, Molly Schieber, Panagiotis Koutakis, Matthew A. Fuglestad, Holly Despiegelaere, G. Matthew Longo, Philippe Malcolm, Jason M. Johanning

School of Podiatric Medicine Publications

Highlights

• Peripheral artery disease (PAD) is a multi-level disease.

• PAD diffusely impairs the performance of leg muscles.

• PAD causes similar irregularities in gait biomechanics regardless of where claudication pain is located in the leg.

Abstract

Background

The most common symptom of peripheral artery disease (PAD) is intermittent claudication that involves the calf, thigh, and/or buttock muscles. How the specific location of this leg pain is related to altered gait, however, is unknown.

Objectives

We hypothesized that because the location of claudication symptoms uniquely affects different leg muscle groups in people with PAD, this would produce distinctive walking patterns.

Methods

A …

A Rare Case Of Biliary Atresia With Biliary Ascites On A (Hepatobiliary Iminodiacetic Acid) Hida Scan, Poonamjeet Loyal, Khalid Makhdomi, Samuel Gitau

Imaging & Diagnostic Radiology, East Africa

Biliary atresia is one of the most challenging conditions in pediatric surgery even when it is the only finding. Here we present a rare case of biliary atresia complicated with biliary ascites due to ductal perforation identified on a hepatobiliary iminodiacetic acid (HIDA) scan.

2023 Nursing Annual Report, Children's Health System Of Texas

2023

No abstract provided.

Detailing The Effects Of Cannabidiol On Exosome Release In Ewing’S Sarcoma, Bennett Hasley

Theses

Ewing’s sarcoma (ES) is a highly aggressive pediatric cancer found within bone that carries a low five-year survival rate within its patients. This is due, in part, to the cancer’s high malignancy properties as well as the development of resistance to the chemotherapies used to combat this cancer. This project aims to determine if cannabidiol (CBD) has an effect on either exosome release or the protein, signal transducer and activator of transcription 3 (STAT3) within ES cells. Exosomes are vesicles that can carry proteins and other signaling molecules which are released by the cell and allow for cell-to-cell communication. Within …

The Ethicality Of Gene Alteration In Human Embryos, Alyssa Scudder

Augustana Center for the Study of Ethics Essay Contest

No abstract provided.

Wcn24-2067 Regional Differences In Acute Kidney Injury In Ugandan Children Hospitalized For Hypoxemia, Anthony Batte, Rodney Ogwang, Robert Opoka, Sophie Namasopo, Michael Hawkes, Andrea Conroy

Paediatrics and Child Health, East Africa

Introduction: Acute kidney injury (AKI) is associated with increased mortality in hospitalized patients and incidence is highest in resource limited settings. The objective of this study was to assess sub-National regional differences in the incidence of AKI in children <5 years of age hospitalized with an acute febrile illness and hypoxemia.

Methods: This was a secondary analysis of a stepped wedge cluster randomized controlled trial, which enrolled children <5 years of age hospitalized with hypoxemia between 2019 and 2021. At least one measure of kidney function was available in 1452 children. A single creatinine was measured at enrolment in a sub-set of 495 children with serum stored and AKI defined using KDIGO criteria where baseline creatinine was estimated using the age-based Pottel equation assuming a normal glomerular filtration rate of 120mL/min per 1.73m2. Markers were divided into structural (uNGAL positive, proteinuria, hematuria) or functional (AKI, saliva urea nitrogen (SUN)) measures of kidney injury.

Results: 1452 children were included in this AKI sub-study (Figure 1). The mean age of participants was 1.49 years (standard deviation (SD), 1.21) and 55.7% were male (809/1452). Overall 2.6% of children died (38/1452). The majority of participants enrolled were from the West (31.3%) …

A Salutogenic Program For Menopause - Enhancing Well-Being With Yoga Therapy, Donna Rachlin

LMU Theses and Dissertations

Menopause, a natural transition for women, often brings about a multitude of physical, psychological, and emotional challenges. As life expectancy rises, a significant portion of a woman's life is spent post-menopause. This thesis explores the potential of yoga therapy as a complementary approach to enhance well-being and improve quality of life during this significant phase. It describes IRB research about Yoga Therapy for Menopause- a salutogenic program that aims to create a safe and educational platform for women who are navigating the changes that menopause brings. This research underscores the effectiveness of yoga therapy as a complementary approach to coping …

Detection And Management Of Post Intensive Care Syndrome, Ann Tomy

Nursing | Student Research Posters

Post Intensive Care Syndrome (PICS) is a collection of symptoms that more than half of patients who survive a critical illness experience after discharge.Those symptoms include weakness, fatigue, sleep disturbances, cognitive dysfunction, post-traumatic stress disorder, mental health conditions, and a lack of effective coping strategies. PICS can significantly impact an individual's quality of life, complicating the recovery process and posing challenges for reintegration into daily activities and societal roles. The etiology of PICS is multifactorial, with the severity and duration of the illness, the nature of medical interventions in the ICU, and the pre-existing health condition of the patient all …

Assessing Lung Cancer Screening Protocols And Outcomes: A Comparative Analysis Between Indonesia And The United States, Priscilla Sitorus

Nursing | Student Research Posters

After losing a loved one to lung cancer, it can be difficult to process, especially when the diagnosis could have been made earlier. However, some may struggle to trust a healthcare system when screening protocols and care vary significantly, to the extent that it may seem unclear. Amongst both men and women, lung cancer is the worldwide leading cause of cancer-related mortality (World Health Organization, 2023), thus further creating a considerable amount of challenges that not only takes part in communities, but the overall healthcare system. Despite the increasing rate of lung cancer, Indonesia has limited screening programs available for …

Crispr, Omega, And Fanzor: Mixed Blessings Of Genome Editing Technology, Haeun Tae

Senior Honors Theses

A little more than a decade ago, CRISPR-Cas system was identified as a potential gene editing tool. This RNA-guided DNA cleavage system, which naturally provides immunity to the prokaryotic host cell, has been engineered since for its application in agriculture, genomic screening, and hereditary genetic disorder treatment and cures. Recently, a eukaryotic CRISPR-Cas-like system, Fanzor, was reported, under a new class of the RNA-guided system (termed OMEGA). The discovery has increased the potentials of genetic modification more than ever, while simultaneously increasing the need for ethical considerations and guidelines. The history, structure, and functions of the two RNA-guided systems, as …

Dean's Report-Spring 2024, Marina K. Holz

GSBMS Dean’s Report

No abstract provided.

Postoperative Discharge Opioid Education Including Narcan Kit Access To Prevent Overdose: A Quality Improvement Project, Arezo Aziz

DNP Projects

Significance and Background: Opioid related overdoses are considered a public health epidemic and emergency in recent years within the United States. With a staggering number of opioid related deaths which have continued to rise, steps have been taken to decrease risk within local communities through programs including personalized patient education during provider visits, the dispensing of Naloxone with opioid prescriptions and encouraging the use of alternative pain management strategies. Most recently, New York State passed a recommendation encouraging all healthcare providers to prescribe Naloxone with the first opioid prescription of each year for patients deemed high risk for overdose. A …

The Impact Of Silver-Impregnated External Ventricular Catheter On The Rate Of Catheter-Related Infection At The Aga Khan University Hospital, Nairobi, Monica Adongo Nyikal

Master of Medicine in General Surgery

Background: 

External Ventricular Drain insertion has been practised at the Aga Khan University Hospital for more than 15 years, with the initial use of plain catheters. Subsequently between 2016 and 2017 the use of Silver-impregnated external ventricular catheters was adopted in the hospital with the aim of reducing external ventricular catheter-related infections. There is a need to assess the effect of the Silver-impregnated external ventricular drain (EVD).

Objectives: 

The primary objective of the study was to determine the difference in the incidence of EVD related infections between the plain EVD and Silver-impregnated EVD at AKUHN in the duration between the …

Towards A Wearable Device For Measuring Impedance Plethysmography Of The Radial Artery, Pritom Chowdhury

Dartmouth College Master’s Theses

Recent advancements in bioimpedance technology have demonstrated significant promise in the application of cardiac health monitoring. This research explores the design and development of a forearm-based wearable bioimpedance device for non-invasive measurement of heart rate and respiratory rate at an accuracy level comparable to medical-grade monitors. It utilizes a tetrapolar electrode configuration to analyze bioimpedance changes in the radial artery due to blood flow.

An ongoing aspect of this work involves the preliminary development of an embedded framework intended to integrate signal generation, acquisition, and processing within the device to achieve compact and efficient system design, anticipated to contribute to …

Using Pose Estimation To Identify Goalkeeper Movement Timing, Chethan Reddy

Health and Kinesiology Theses

Background: Markerless human pose estimation has the potential to revolutionize sports analytics by providing detailed insights into athlete movement. The research presented in this thesis explores how open source pose estimation can be utilized to identify goalkeeper dive initiation during soccer penalty kicks.

Purpose: The purpose of this study is to provide an accessible, low-cost heuristic methodology for identifying goalkeeper dive initiation.

Methods: This study uses high-definition single camera broadcast footage (1080p resolution, 50 frames per second) of all 41 penalty kicks attempted during the 2022 FIFA Men’s World Cup. We isolated each penalty kick from kicker run-up to kick …

Passenger Traits That Predict The Bystander Intervention Model Steps During An Inflight Assault On A Flight Attendant, Michael Pettit

Doctoral Dissertations and Master's Theses

Every major U.S. airline has experienced a violent inflight assault on one of their flight attendants. The problem is becoming more widespread, but industry leaders have few coping strategies. The first step toward addressing the issue is understanding the various aspects of the event, including the actions of other passengers (bystanders) who may witness the assault. There is ample literature on bystander reactions to similar events such as bullying, medical emergencies, injuries, and violent attacks, but none dedicated to a flight attendant assault or passenger reactions to it.

At the core of bystander action is the bystander effect, which postulates …

Uncemented Total Knee Arthroplasty Is On The Rise. A Retrospective Review From The Michigan Arthroplasty Registry Collaborative Quality Initiative (Marcqi), Michael E. Sacchetti, Sarah Fried, Madeleine Declercq, Jacob H. Keeley, Robert Runner

Conference Presentation Abstracts

OBJECTIVE: Cemented total knee arthroplasty (TKA) is the gold standard treatment for osteoarthritis, but uncemented TKA offers benefits like improved osseointegration and reduced complications from cement debris. This study aimed to investigate (1) if there has been a rise in uncemented TKA and (2) if there are differences in early complications between cemented and uncemented TKA. METHODS: We retrospectively reviewed data from the Michigan Arthroplasty Registry Collaborative Quality Initiative (MARCQI) database of primary TKA patients from 2017 to 2021 at a single health system (six hospitals). Uncemented TKA (uncemented fixation for femur and tibia) patients were analyzed for demographics and …

The Effect Of A Positive Work Culture In Emergency Service Nurses: An Ebp Proposal, Brianna M. Fitzgerald

MSN Capstone Projects

This paper aims to address the spirit of inquiry of the effect a safe work environment has on compassion fatigue in nurses in the emergency department (ED). The World Health Organization promotes an eager approach to the battle of compassion fatigue in frontline healthcare workers, stating, "Unless this is addressed, it will further add to the global nursing workforce shortage." (Stafford et al., 2022, p. 1853). Unfortunately, 69% of nurses under the age of 25 report burnout from working conditions (American Nurses Association, 2022). Improving nurses' job satisfaction and motivation levels is necessary to increase the effectiveness of nursing services …

Academic Performance Among Pharmacy Students Using Virtual Vs. Face-To-Face Team-Based Learning, Osama A. Shoair

Pharmacy Faculty Publications and Presentations

Introduction

This study compares pharmacy students’ performance using face-to-face (FTF) team-based learning (TBL) vs. virtual TBL across multiple courses and different academic levels while accounting for student demographic and academic factors.

Methods

The study included pharmacy students from different academic levels (P1–P3) who were enrolled in three didactic courses taught using FTF TBL and virtual TBL. Multiple generalized linear models (GLMs) were performed to compare students’ performance on individual readiness assurance tests (iRATs), team readiness assurance tests (tRATs), team application exercises (tAPPs), summative exams, and total course scores using FTF TBL vs. virtual TBL, adjusting for students’ age, sex, race, …

Implementing An Approach To Prevent Life-Threatening Bleeding: Guidance On Forming A Campus Initiative, Elizabeth Caulkins, Katheryn Courville Johnston, Belinda Deal, Amanda Swanberg, Glenn A. Barnes, Jessica Bowen

Nursing Faculty Publications and Presentations

A community that is trained to respond to life-threatening bleeding can reduce the risk of death from trauma and violence. Stop The Bleed is a nationally recognized, free, 1- hour bleeding control training designed for laypersons. Implementing a campus-wide Stop the Bleed initiative can be daunting, yet vital to creating a safe, prepared campus. Guidance is offered by faculty, staff, and students from a Stop the Bleed initiative at a public university in the southern United States. This guide provides real-life examples and recommendations based on experience. Utilization of population health nursing students is a fundamental component of success.

Mediating Effect Of Bmi On The Association Of Economic Status And Coexistence Of Hypertension And Diabetes In Bangladesh: A Counterfactual Framework-Based Weighting Approach, Foyez , Md. Jamal Hossain Ahmmed, Md. Jamal Hossain, Md Tareq Ferdous Khan, Muhammad Mahabub Rahaman Manik, Saimon Shahriar, Dulal Chandra Nandi, Md Parvej Hussain

Mathematics and Statistics Faculty Publications

Background and Aims

Non-communicable diseases such as hypertension and diabetes are matters of huge concern worldwide, with an increasing trend in prevalence over the previous decade. First of all, this study aimed to evaluate the association between economic status (ES) and body mass index (BMI), ES and comorbidity of hypertension and diabetes, and BMI and comorbidity independently. Second, it explored the mediating role of BMI in the association between ES and comorbidity of hypertension and diabetes. Finally, it investigated whether the mediating effect differs with the place of residence, gender, and education levels.

Methods

A total of 11,291 complete cases …

Hearing Loss In Children With 22q11.2 Deletion Syndrome, Lori Yaktine, Amanda Moore, Jamie Hamm, Blaine Crowley, Meghan Tracy, Janelle R. Noel-Macdonnell Phd, Kim Graiser, Bernice Marrow, Hansoo Song, Srivats Narayanan, Nikita Raje, Donna Mcdonald-Mcginn, Jill M. Arganbright

Posters

22q11.2 deletion syndrome (22q11.2DS) is the most common microdeletion syndrome, with most recent published prevalence of 1:2,140 live births. Hearing loss is common in children with 22q11.2DS and has been reported to occur in 32-60% of people. Hearing loss is typically conductive in nature secondary to chronic eustachian tube dysfunction and chronic otitis media with effusion (COME). Close monitoring of hearing and the middle ears is recommended to detect COME and the need for ear tubes. Additionally, there is a high prevalence of speech delay in children with 22q11.2DS, stressing the importance of close audiometric evaluation and medical intervention as …

Anterior Hip Pain In Adolescent Female Wrestler, Melanie Kennedy

Posters

No abstract provided.