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Full-Text Articles in Medicine and Health Sciences

Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr May 2024

Information Feedback Delays Within Epidemic Models And Their Effect On Model Dynamics., Maria K. Bouka, Christopher Strickland Dr

Biology and Medicine Through Mathematics Conference

No abstract provided.


Optimizing Immunotherapies For Improved Cancer Treatment, Anne Talkington, Anthony Kearsley May 2024

Optimizing Immunotherapies For Improved Cancer Treatment, Anne Talkington, Anthony Kearsley

Biology and Medicine Through Mathematics Conference

No abstract provided.


Teacher Voices: Stress And Coping Mechanisms Among The Teaching Profession, Jasmine Suttles May 2024

Teacher Voices: Stress And Coping Mechanisms Among The Teaching Profession, Jasmine Suttles

Education | Master's Theses

Stress is a natural response that occurs in our body when we feel overwhelmed, and it can manifest in both positive and negative instances. The teaching profession is not exempt from this phenomenon, as it is unique in that educators have multiple roles to play and have to manage and interact with many students simultaneously. Teachers have been described as "exasperated by heavy loads of emotional labor in the classroom" (Ferguson et al., 2022). This "heavy load" can place the teaching profession at risk of stress and burnout if self-care is not addressed or mental health resources are not offered. …


Topological Data Analysis Of Molecular Dynamics Simulations Of Monoclonal Antibodies, Melinda Kleczynski, Christina Bergonzo, Anthony Kearsley May 2024

Topological Data Analysis Of Molecular Dynamics Simulations Of Monoclonal Antibodies, Melinda Kleczynski, Christina Bergonzo, Anthony Kearsley

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Stochastic Multi-Host Model For West Nile Virus: Determining The Probability Of Disease Extinction!, Suzanne Robertson May 2024

A Stochastic Multi-Host Model For West Nile Virus: Determining The Probability Of Disease Extinction!, Suzanne Robertson

Biology and Medicine Through Mathematics Conference

No abstract provided.


Stochastic Immunology Model And Its Analysis, Rahnuma Islam, David Swigon May 2024

Stochastic Immunology Model And Its Analysis, Rahnuma Islam, David Swigon

Biology and Medicine Through Mathematics Conference

No abstract provided.


Clustering Using Self Organizing Maps In Biology, Olcay Akman May 2024

Clustering Using Self Organizing Maps In Biology, Olcay Akman

Biology and Medicine Through Mathematics Conference

No abstract provided.


Decoding Immune Cell Navigation: Integrating Artificial Life Modeling With Tumor Microenvironment Dynamics, Sadegh Marzban May 2024

Decoding Immune Cell Navigation: Integrating Artificial Life Modeling With Tumor Microenvironment Dynamics, Sadegh Marzban

Biology and Medicine Through Mathematics Conference

No abstract provided.


Variation In Systemic Corticosteroid Prescribing During Asthma-Related Hospitalizations Across Children's Hospitals, Sian Best, Kathryn Kyler, Matt Hall, Jessica L. Bettenhausen, Shelby Chesbro, Nicholas Clark, Adrienne Deporre, Jonathan Ermer, Leah Jones, Jessica Markham, Maria Newmaster, Laura Plencner, Henry T. Puls, Smit Shah, Bridgette Jones, Megan Collins, Elisha Mccoy May 2024

Variation In Systemic Corticosteroid Prescribing During Asthma-Related Hospitalizations Across Children's Hospitals, Sian Best, Kathryn Kyler, Matt Hall, Jessica L. Bettenhausen, Shelby Chesbro, Nicholas Clark, Adrienne Deporre, Jonathan Ermer, Leah Jones, Jessica Markham, Maria Newmaster, Laura Plencner, Henry T. Puls, Smit Shah, Bridgette Jones, Megan Collins, Elisha Mccoy

Research Days

This abstract describes the variability and trends in inpatient systemic corticosteroid prescribing practices for acute asthma exacerbations in children's hospitals, and aims to determine associations between the prescribed steroid and hospitalization outcomes.


Bowel Clean Out Prior To Intrathecal Baclofen Pump Implantation: Effects On Acute Post-Operative Gastrointestinal Complications, Amanda Lindenberg, Sathya Vadivelu, Brittni Walton, Matthew J. Mclaughlin May 2024

Bowel Clean Out Prior To Intrathecal Baclofen Pump Implantation: Effects On Acute Post-Operative Gastrointestinal Complications, Amanda Lindenberg, Sathya Vadivelu, Brittni Walton, Matthew J. Mclaughlin

Research Days

Background: Intrathecal baclofen (ITB) pumps have been used for management of spasticity and dystonia There is limited data on immediate post-operative complications such as GI adverse events after surgery for ITB pump related procedures. This study aimed to compare patients who underwent a pre-operative bowel cleanout to those who did not and the relationship with post-operative nausea, vomiting and constipation requiring an escalation of their bowel regimen.

Design: Retrospective cohort study.

Setting: Pediatric acute care hospital.

Participants: All patients who underwent new ITB pump and/or catheter placement from January 2015-December 2022.

Interventions: Preoperative bowel clean out. Main

Outcome Measure: Quantity …


Therapeutic Efficacy Of B7-H3 Car T Cell Therapy In Pediatric High-Grade Gliomas With H3g34r/V Mutation., Monika Yadav, Siddharth Subham, John Szarejko, Douglas Myers, David Akhavan, Viveka Nand Yadav May 2024

Therapeutic Efficacy Of B7-H3 Car T Cell Therapy In Pediatric High-Grade Gliomas With H3g34r/V Mutation., Monika Yadav, Siddharth Subham, John Szarejko, Douglas Myers, David Akhavan, Viveka Nand Yadav

Research Days

Background: Pediatric high-grade gliomas (pHGGs) are aggressive brain tumors responsible for significant childhood mortality. These tumors often carry mutations in the H3F3A gene, which encodes histone H3.3 proteins. However, current treatment options are limited, underscoring the need for innovative approaches. Chimeric antigen receptor (CAR) therapy, which was successful in treating certain childhood cancers, holds promise for pHGGs with H3G34R/V mutations. This study aims to assess the potential of anti-B7-H3 CAR T cell therapy in treating the challenging pHGG tumors.

Method and Results: Here, we examined the expression of B7-H3 in various pHGG cell lines, encompassing those with H3G34V/R and H3K27M …


Characterizing New Invasive Infections In Children’S Mercy Extracorporeal Membrane Oxygenation And And Continuous Renal Replacement Therapy Patients, Samantha M. Davidson, Jay F. Rilinger, Jenna O. Miller, Caroline Holten, Josh Herigon May 2024

Characterizing New Invasive Infections In Children’S Mercy Extracorporeal Membrane Oxygenation And And Continuous Renal Replacement Therapy Patients, Samantha M. Davidson, Jay F. Rilinger, Jenna O. Miller, Caroline Holten, Josh Herigon

Research Days

This abstract characterizes the patients at Children's Mercy who developed a new serious bacterial infection while on extracorporeal support.


Central Venous Catheter-Associated Complications In Pediatric Patients With Acute Myeloid Leukemia, J Allyson Hays, Maggie Ziegler May 2024

Central Venous Catheter-Associated Complications In Pediatric Patients With Acute Myeloid Leukemia, J Allyson Hays, Maggie Ziegler

Research Days

Background

Central venous catheters (CVCs) are a mainstay of pediatric cancer treatment for but have risks. CVCs can cause local site infections and systemic infections, known as central-line-associated bloodstream infections (CLABSIs). Analyzing rates of complications associated with different CVCs may inform future decisions about CVC choice. Hypotheses We hypothesized that tunneled cuffed (tunneled) catheters will have higher rates of CLABSIs compared to implanted ports (port) and ports will have higher rates of local site infections compared to tunneled.

Methods

Retrospective chart review of patients with acute myeloid leukemia (AML) at Children’s Mercy Hospital (CMH) identified patients treated from 2010 to …


Pediatric Caregiver Perspectives On Immigration Status In The Healthcare Setting, Anik Patel, Kimberly Randell, Jennifer Watts, John Cowden, Frances Turcotte Benedict, Juan Farias Torres, Ana Contreras, Ali Fowler, Estefania Bazan, Claudia Zepeda May 2024

Pediatric Caregiver Perspectives On Immigration Status In The Healthcare Setting, Anik Patel, Kimberly Randell, Jennifer Watts, John Cowden, Frances Turcotte Benedict, Juan Farias Torres, Ana Contreras, Ali Fowler, Estefania Bazan, Claudia Zepeda

Research Days

A qualitative study to explore pediatric parent/caregiver knowledge, attitudes, and beliefs regarding impacts of immigrant status on healthcare and describe health and social needs of families for whom one or more caregivers has undocumented immigration status as well as preferred methods for resource connections among undocumented caregivers.


Frailty In Children And Adolescents With Acute Lymphoblastic Leukemia Or Lymphoblastic Lymphoma Receiving Maintenance Chemotherapy – A Pilot Study, Thomas R. Cochran, Joy M. Fulbright, Samantha Butrous, Brian R. Lee, Keith J. August, David A. White May 2024

Frailty In Children And Adolescents With Acute Lymphoblastic Leukemia Or Lymphoblastic Lymphoma Receiving Maintenance Chemotherapy – A Pilot Study, Thomas R. Cochran, Joy M. Fulbright, Samantha Butrous, Brian R. Lee, Keith J. August, David A. White

Research Days

The submitted study aims to identify children with acute lymphoblastic leukemia or lymphoblastic lymphoma that meet frailty criteria early to allow for prevention of chronic health conditions that lead to increased mortality as survivors age into adulthood. Prevention and/or reversal of frailty has the potential to improve quality of life, decrease burden of disease, and extend the lifespan of the growing population of childhood cancer survivors. Given that frailty has been accepted as a tool to identify elderly and chronically sick adults highly vulnerable to adverse health outcomes, better understanding of the relevance and applicability of frailty in pediatrics may …


Increasing Feedback From Endocrinology Faculty To Fellows: A Quality Improvement Initiative, Emily Metzinger, Emily Griffing, Michelle Knoll May 2024

Increasing Feedback From Endocrinology Faculty To Fellows: A Quality Improvement Initiative, Emily Metzinger, Emily Griffing, Michelle Knoll

Research Days

Feedback is essential in medical training. Our aim is to increase the frequency of feedback that CMH endocrinology fellows receive in both the inpatient and outpatient settings. We noted initial success of increasing feedback in the inpatient setting however later decreased to below goal. Frequency of feedback in the outpatient setting has remained below goal. Tracking feedback has been challenging, but a recent survey showed that fellows perceive that they receive more feedback.


Plenary: Mathematics Of Malaria Transmission Dynamics: The Renewed Quest For Eradication, Abba Gumel May 2024

Plenary: Mathematics Of Malaria Transmission Dynamics: The Renewed Quest For Eradication, Abba Gumel

Biology and Medicine Through Mathematics Conference

No abstract provided.


Explaining The Staircase Gelb Illusion, Simultaneous Contrast, And Perceptual Fading Of Stabilized Images With A Neural Model Driven By Fixational Eye Movements, Michael E. Rudd May 2024

Explaining The Staircase Gelb Illusion, Simultaneous Contrast, And Perceptual Fading Of Stabilized Images With A Neural Model Driven By Fixational Eye Movements, Michael E. Rudd

MODVIS Workshop

A neural model of lightness computation driven by fixational eye movements is described and used to simulate various lightness phenomenon, including the Staircase Gelb illusion and its variants, simultaneous contrast, the Chevreul illusion, and perceptual fading of stabilized images. The model provides a precise account of the lightness matches from several experiments, with an overall error of only 1.5%. In the model, spatial maps of transient ON and OFF cell activations—produced as the eyes traverse the visual scene—are sorted by eye movement direction in visual cortex. At a subsequent processing stage, the activations within these maps are summed across space …


Plenary: Insights Into Depression: Mathematical Approaches, Janet Best May 2024

Plenary: Insights Into Depression: Mathematical Approaches, Janet Best

Biology and Medicine Through Mathematics Conference

No abstract provided.


Addressing Mental Health In Young Adults: A Modern Approach Compared To Previous Generations, Breeha A. Shah May 2024

Addressing Mental Health In Young Adults: A Modern Approach Compared To Previous Generations, Breeha A. Shah

DePaul Journal of Health Care Law

The escalating prevalence of mental health issues among today's young adults underscores the vital importance of addressing mental health in the pursuit of public health objectives. In response to this, The House Education and Labor Committee issued a report on the Mental Health Services for Students Act of 2020 (the Act), to amend the Public Health Service Act relating to school children. This revision seeks to bolster the support for students and young people by ensuring their access to comprehensive mental health programs within the school environment. The Act recognizes that safeguarding mental health is an immediate concern for public …


Are We Listening? Approaches To Community-Centered Needs Assessment, Mikayla Gallo, Amanda Tyler May 2024

Are We Listening? Approaches To Community-Centered Needs Assessment, Mikayla Gallo, Amanda Tyler

Georgia Public Health Association Annual Meeting & Conference

Background: The United States Department of Agriculture (USDA) has encouraged Supplemental Nutrition Assistance Program (SNAP) state agencies to lead needs assessment activities to guide funding and program decision-making for the SNAP Nutrition Education and Obesity Prevention Grant Program (SNAP-Ed). The Georgia Department of Human Services (DHS),decided to center the voices of SNAP-Ed participants in Georgia through a series of listening sessions occurring January to October 2023. The goal of the community listening session (CLS) was to discuss community needs based on local health data, identify existing community assets, identify barriers to accessing healthy food and active living, ideate solutions that …


Propensity-Score Matching Beginning And Experienced Farmers On Stress And Coping Mechanisms To Predict Suicidal Ideation, Anne Montgomery, Stephanie M. Basey, Chris T. Scoggins, Lily Baucom May 2024

Propensity-Score Matching Beginning And Experienced Farmers On Stress And Coping Mechanisms To Predict Suicidal Ideation, Anne Montgomery, Stephanie M. Basey, Chris T. Scoggins, Lily Baucom

Georgia Public Health Association Annual Meeting & Conference

This presentation is an extension of a roundtable from last year; we added propensity-score matching thanks to suggestions from the roundtable:

The suicide rate among farmers is much higher than that of the overall working population. Literature on farmer mental health in Georgia has been scarce and mostly focused on farmer suicide. This study looks at the influence of being a beginning farmer (less than 10 years of experience) on farm-related stressors and coping mechanisms.

This cross-sectional study inventories mental well-being, stressors, and coping mechanisms for different types of farmers. Participants (N=1,328) were asked demographics, household composition, work descriptors, healthcare …


Let's Talk About Sex & Prep: District 2 Does!, Chrissa M. Shaffer May 2024

Let's Talk About Sex & Prep: District 2 Does!, Chrissa M. Shaffer

Georgia Public Health Association Annual Meeting & Conference

Defining what a PrEP Service Program entails and how it could benefit your district or county health center. Discussing methods that have been used to set up PrEP Services within a district – including training, resources, and promotion. Identifying the challenges and working through them. Reviewing the results of the PrEP Services over the past year, and the ongoing goals to encourage and increase our PrEP Services.


Gender-Based Differences In Stress And Coping Among Farmers: A Cross-Sectional Study With Propensity Score Matching, Anne Montgomery, James B. Dunaway, Stephanie M. Basey, Chris T. Scoggins, Lily R. Baucom May 2024

Gender-Based Differences In Stress And Coping Among Farmers: A Cross-Sectional Study With Propensity Score Matching, Anne Montgomery, James B. Dunaway, Stephanie M. Basey, Chris T. Scoggins, Lily R. Baucom

Georgia Public Health Association Annual Meeting & Conference

This cross-sectional study compares the mental health experiences of male and female farmers, with a particular focus on stress levels, stressors, and coping mechanisms. The research aims to shed light on gender-based differences in stress experiences and coping strategies among agricultural workers. The study involved 1,394 farmers (67.7% male, 32.3% female) from Georgia, USA, who completed an online survey on aspects of mental well-being.

Findings indicate that female farmers were more likely to hold farm manager roles and less likely to be farm owners. Notably, a higher proportion of female farmers were first-generation farmers, indicating potential unique challenges for this …


The Future Of Public Health: Developing The Workforce Through Public Health Americorps, Kristi James May 2024

The Future Of Public Health: Developing The Workforce Through Public Health Americorps, Kristi James

Georgia Public Health Association Annual Meeting & Conference

The American Public Health Association (APHA) and its Alliance for Disease Prevention and Response worked closely with the Public Health AmeriCorps program (PHACP), CDC and AmeriCorps on a set of activities which strengthen workforce capacity. Within APHA and its Alliance for Disease Prevention and Response team, the assigned project consists of providing opportunities for Public Health AmeriCorps members and grantees to make new connections and increase engagement with those in the field. The overall goal of the project is to address the critical need for public health professionals by supporting the recruitment, training, and development of the next generation of …


The Palestinian Feature Film "200 Meters" Addresses The Issue Of The Apartheid Wall, Samar Abd Al Karim Farahat May 2024

The Palestinian Feature Film "200 Meters" Addresses The Issue Of The Apartheid Wall, Samar Abd Al Karim Farahat

Middle East Journal of Communication Studies

This study aimed to explain the methods of processing the Palestinian feature film" 200 meters " to the issue of the apartheid wall, using sub-objectives highlighting political, social and psychological issues and topics in addition to the characters and cinematic elements, to identify the form of processing carried out by the film in an integrated manner. Given the nature of this study, which aimed to find out how the 200-meter film dealt with the issue of the apartheid wall, the researcher adopted the most appropriate approach to studying this type of phenomena, which is the analytical approach. The results of …


Assessment Of Gait, Balance, And Falls In Individuals With Neurodegenerative Diseases, Lauren Tueth May 2024

Assessment Of Gait, Balance, And Falls In Individuals With Neurodegenerative Diseases, Lauren Tueth

WUSM Theses and Dissertations – All Programs

Neurodegenerative diseases are a group of disorders that impact the brain and lead to neuronal degeneration. This degeneration causes many different symptoms, which are often grouped into motor, cognitive, and psychiatric domains. Individuals with these disorders can experience symptoms from multiple domains at the same time, but little is known about how these distinct symptoms may impact each other.

In Chapter 2, we explored the intersection of balance and cognitive impairment in individuals with Alzheimer disease (AD). AD is traditionally discussed in the context of the dementia symptoms, but people with AD also experience motor deficits. Falls are a huge …


Measurement Of And Contributors To Developmental Coordination Impairment, Jeffrey D. Konrad May 2024

Measurement Of And Contributors To Developmental Coordination Impairment, Jeffrey D. Konrad

WUSM Theses and Dissertations – All Programs

Movement drives childhood development. As motor skills improve across development, a child becomes capable of greater interactions with their physical and social environment. Children with motor impairments miss out on these interaction opportunities and their development across a variety of domains can suffer. There is accumulating evidence that poor motor competence relates to an array of developmental outcomes such as educational achievement, reading skills, social development, and emotional regulation. Two developmentally important motor impairments are poor motor competence and hyperactivity which are associated with Autism Spectrum Disorder (ASD), Developmental Coordination Disorder (DCD), and/or Attention Deficit Hyperactivity Disorder (ADHD). Critical to …


Medical School Watercooler Newsletter - May 15, 2024, Lindsey Lyle May 2024

Medical School Watercooler Newsletter - May 15, 2024, Lindsey Lyle

Watercooler Newsletter

This is the May 15, 2024 edition of the Frederick P. Whiddon College of Medicine’s newsletter - Watercooler.

Contents Include

  • DEI Book Club to discuss 'Pregnant While Black'
  • Online graduate certificate in Spanish offered for healthcare professionals
  • Submit 'A Note for Every White Coat' by June 7
  • Community preceptors honored at appreciation event


Antibiotic-Induced Changes In Efflux Transporter Expression: A Key Factor In Pseudomonas Aeruginosa Biofilm Resistance, Zara Imtiaz, Avinash Chatoo, Will Wang, Weiqi Li, Paramita Basu May 2024

Antibiotic-Induced Changes In Efflux Transporter Expression: A Key Factor In Pseudomonas Aeruginosa Biofilm Resistance, Zara Imtiaz, Avinash Chatoo, Will Wang, Weiqi Li, Paramita Basu

Touro College of Pharmacy (New York) Publications and Research

Listed by WHO as an antibiotic-resistant priority pathogen, Pseudomonas aeruginosa(P.A.) is a serious threat in nosocomial infections. Its high antibiotic resistance is attributed to major mechanisms that can be categorized into intrinsic, acquired, and adaptive resistance. This study tests the ability of three commonly used antibiotics to inhibit new biofilm formation and eradicate mature biofilm growth, as well as investigate changes in the expression levels of selected genes coding for multidrug efflux pumps in P.A. planktonic cells and biofilms before and after treatment with antibiotics to provide a conceptual estimate of the activity of the efflux transporters that work to …