Medicine and Health Sciences Commons^™

Applying Evidence-Based Practice To Guide Occupational Therapy In The Nicu And Outpatient-Based Early Intervention Settings, Brooke A. Wilson

Occupational Therapy Capstone Presentations

Infants admitted to the neonatal intensive care unit (NICU) are at increased risk for feeding difficulties, developmental delays, and sensory processing challenges due to prematurity and complex medical needs. These effects often persist into the first years of a child’s life, and many receive early intervention or outpatient therapies. Occupational therapy plays a critical role in addressing these concerns while supporting caregivers in building knowledge and confidence. The purpose of this capstone project was to develop in-depth clinical skills in the NICU and outpatient early intervention settings, educate caregivers, and complete continuing education courses related to neonatal and pediatric therapeutic …

Addressing The Motor And Non-Motor Symptoms Of Parkinson’S Disease Through Integration Of Clinical Skills And Community Educational Resources, Alison C. Lee

Occupational Therapy Capstone Presentations

Individuals with Parkinson’s Disease (PD) face many challenges to their daily life including various motor and non-motor symptoms that affects their participation in meaningful occupations. Non-motor symptoms like decreased social participation, sleep disturbances, fatigue, and decline in cognition often go unnoticed and undertreated. Limited resources are available to clinicians and individuals with PD regarding tangible ways to address these concerns. Occupational therapy (OT) has a unique role in addressing both motor and non-motor symptoms through evidence-based resources, education, and general awareness. This project bridged this gap in care regarding non-motor symptoms of PD through the creation of easily accessible handouts, …

Improving Occupational Performance In Vision Neurorehabilitation, Catherine Lentsch

Occupational Therapy Capstone Presentations

Visual dysfunction affects up to 90% of individuals with traumatic brain injuries and up to half of stroke survivors, significantly impacting independence in daily occupations. This capstone project, conducted at Nebraska Methodist Hospital, aimed to improve clients’ occupational performance and enhance occupational therapy vision neurorehabilitation through advanced clinical skill development and the development of resources. The project involved the evaluation and treatment of eleven neurological patients across inpatient and outpatient settings. Guided by Warren’s Hierarchy of Visual Perceptual Skills and Toglia’s Dynamic Interactional Approach, the project emphasized stabilizing foundational visual skills before progressing to higher‑level visual-perceptual tasks and used near …

Fragile Patients, Intentional Care: Nonpharmacological Pain Management Treatment Approaches In The Neonatal Intensive Care Unit (Nicu), Kristie A. Moeller

Occupational Therapy Capstone Presentations

The aim of this project was to increase clinical skills in a level III neonatal intensive care unit (NICU) and explore how nonpharmacological occupational therapy (OT) interventions impact pain management in the NICU for a variety of patients. Due to the increasing rates of admissions to the NICU and the impact that pain has on child development there was a clear need to gain skills to create interventions that would minimize the effect on infant development (Martin & Osterman, 2025; Pineda et al., 2025). The needs assessment revealed the need for occupational therapists (OTs) role in nonpharmacological pain management to …

Beyond The Court: Pickleball's Impact On Balance And Gait In Older Adults, Riley Scott Ahrndt, Abby Nicole Bertsch, Emma Florence Boris, Gabrielle Elizabeth Rheay, Isabella Cason Whiston

Physical Therapy Scholarly Projects

Background and Purpose: Older adults are at a greater risk for falls due to many variables that may include decreased balance, lower extremity strength, slower agility, and impaired gait mechanics. Daily physical activity has been shown to help combat age-related deficits. The popularity of pickleball is growing fast and may provide an option for exercise that incorporates strength, agility, balance, and aerobic effort. The goal of this study was to examine the effects of pickleball on the balance and agility of older adults participating in the National Senior Games organization.

Methods: The modified version of the Senior Athlete Fitness Exam …

Cardiovascular Health Outcomes In Senior Athletes: A Comparative Study Of Pickleball And Other Recreational Sports, Breana Alise Tretter, Lynsay Leilani Benson, John Thomas Polejewski, Jeremiah Sanders Talley

Physical Therapy Scholarly Projects

Background and Purpose: Pickleball has grown rapidly in popularity among older adults and is often promoted as a beneficial form of exercise for cardiovascular health. The purpose of this study was to evaluate whether senior athletes who participate in pickleball exhibit significantly better cardiovascular fitness compared to peers participating in other sports at the North Dakota Senior Games.

Methods: The data was collected through the Sustained Athlete Fitness Exam (SAFE), a multi-component fitness screening conducted by the University of North Dakota’s Physical Therapy Department. The screening included assessments of vital signs, body mass index (BMI), and mobility. Participants voluntarily enrolled …

Building Dental Workforce Pathways In A Rural State Without A Dental School, Rashid Ahmad, Shawnda Schroeder

Indigenous Health Posters and Presentations

In North Dakota, workforce shortages are shaped by geography, training pathways, and weak return incentives.

• Statewide Dental Health Professional Shortage Area designation
• No in-state dental school
• Workforce shortages function as a structural driver of inequity • Oral health disparities among children, low-income populations, and Indigenous communities

Immersive Visualization Of Cardiac Segmentation And Analysis, Brandon Norman

Theses and Dissertations

Coronary artery disease remains one of the leading causes of death worldwide, making early detection and treatment critical to reducing mortality. While coronary angiography remains the gold standard procedure for diagnosing coronary artery disease, less invasive methods such as coronary computed tomography angiography and virtual fractional flow re-serve continue to improve. However, taking full advantage of volumetric coronary computed tomography angiography data requires extensive post-processing before the data can support geometric modeling, hemodynamic simulation, and analysis. Existing Open-Source Appli-cations provide powerful tools for these tasks, but their interaction models remain largely desktop based, restricting users to 2d manipulation and hindering …

The Impact Of Glucose Exposure On Organic Cation Transporters (Oct) Function In A Corneal Epithelial Cell Line, David A. Garza

Theses & Dissertations

Organic cation transporters (OCT) facilitate the movement of neurochemicals and medications, contribute to the removal of cellular waste, and facilitate neuronal communication. Three subtypes of these high-capacity, low-affinity transporters (OCT1, OCT2, and OCT3) are differently expressed in peripheral tissues such as the liver, kidneys, as well as the central nervous system. OCTs are also expressed in ocular tissues. Chronic hyperglycemia is a complication commonly associated with diabetes that can lead to ocular diseases such as diabetic keratopathy, which affects the cornea. In this project, we expose immortalized human corneal epithelial cells (HCE-S) to various glucose concentrations to study their impact …

Chemical Variability In The Unregulated Opioid Supply In The South Bronx, Yeireline Rodriguez

Student Theses

The unregulated drug supply in the United States has become increasingly unpredictable, contributing to persistently high overdose mortality, particularly in structurally marginalized communities such as the South Bronx. While drug adulteration has long been present in illicit markets, the number and pharmacological diversity of adulterants remained limited for much of the twentieth century. Over the past decade, however, the drug supply has undergone a significant transformation marked by the proliferation of potent synthetic opioids such as fentanyl and its analogues, frequently combined with novel sedatives and chemically diverse adulterants. These shifts have introduced increasing chemical complexity into the street drug …

The Effect Of Fall Prevention Programs With Hourly Rounding On Fall Rates Among Adults Patients In Neurological Unit, Oyinlola A. Ogundeji

Doctor of Nursing Practice Final Project Abstract

Purpose

The purpose of this QI project was to evaluate the effect of a structured hourly rounding program on patient fall rates in an adult neurological inpatient unit.

Background

Patient falls remain a major safety concern in acute care, particularly among hospitalized neurological patients with impairments in mobility, cognition, and balance. In an adult neurological unit within a Magnet-designated hospital, fall rates exceeded national benchmarks, underscoring the need for a targeted quality-improvement

Methodology

A pre–post QI design, guided by the Plan-Do-Study-Act framework, was implemented over 12 weeks in a 28-bed neurological unit. This intervention featured structured hourly rounding using the …

Bio 23 Human Anatomy & Physiology I Syllabus, Rujin Tian

Open Educational Resources

The syllabus for BIO 23 contains a course description, course objectives, course readings divided by week and a link to an OER textbook.

Bio 24 Human Anatomy And Physiology Ii, Rujin Tian

Open Educational Resources

The syllabus for BIO 24 contains a course description, course objectives, course readings divided by week and a link to an OER textbook.

Prefrontal Engagement In Cognitive Flexibility Across Paradigms, Katarina Kalajzic

Honors Scholar Theses

Cognitive flexibility is an executive function that involves dynamically adapting behavior in the face of changing environmental circumstances to achieve a particular goal. Disrupted in numerous psychiatric disorders such as Alzheimer’s disease, schizophrenia, OCD, and depression, the neural correlates of cognitive flexibility are not well understood. However, the prefrontal cortex (PFC) is strongly implicated in executive function and attentional control processes. Thus, we sought to examine the neural circuitry involved in distinct cognitive flexibility tasks – the attentional set-shifting task and the probabilistic 2-armed bandit task. Through optogenetic suppression, we targeted pyramidal neurons of the rodent medial prefrontal cortex, an …

Factors Affecting Pedestrian-Vehicle Conflicts: An Empirical Analysis, Christo D. Jamo

Honors Scholar Theses

The number of pedestrian deaths increased by 78% between 2009 and 2023, while other motor vehicle crash deaths increased by 13% in the same period [1]. To identify potential pedestrian safety measures, this study analyzed the effects of location-based demographics, pedestrian phasing type, and other physical infrastructure and behavior variables on the probability of pedestrian-vehicle conflicts at signalized intersections, which is a surrogate measure of crash risk. Data were collected from 55 intersections in Connecticut, and the pedestrian-vehicle interactions were classified by severity based on the Swedish Traffic Conflict Technique: undisturbed passage, potential conflict, minor conflict, or serious conflict. Because …

From Prescription To Plate: Redefining The Pharmacist’S Role In Food Is Medicine Initiatives, Aleena R. Thomas

Honors Scholar Theses

Produce prescription (PRx) programs are an emerging Food is Medicine intervention designed to address diet-related chronic diseases and food insecurity by integrating healthcare delivery with access to fruits and vegetables. Diet-related conditions such as type 2 diabetes, hypertension, and cardiovascular disease represent a major public health burden in the United States, particularly among populations with limited access to nutritious food. Despite growing evidence supporting PRx programs, pharmacists -- who routinely manage these conditions and monitor outcomes -- are underutilized in program implementation. The objective of this project is to translate the public health aspects of PRx programs into an accessible, …

Diagnostic Ability Of Rate Of Torque Development For Patellofemoral Pain, Arun Loganathan, Neal R. Glaviano Phd, Sungwan Kim Phd

Honors Scholar Theses

Context: Patellofemoral pain (PFP) is a highly prevalent condition (22.7% in general population) that significantly impacts the quality of life of those who suffer from it. However, there is no gold standard test to diagnose it yet, leading to inconsistencies with treatment as well as delayed intervention. Rate of torque development (RTD) is a neuromuscular measure that has shown strong connections to PFP.

Objective: The purpose of this study is to determine the diagnostic ability of RTD for PFP.

Design: Cross-sectional.

Setting: Laboratory.

Participants: Thirty-five individuals with PFP (24 males and 11 females, 22.7 ± 3.7 years, 1.67 ± 0.1 …

Validation Of A Real-Time Pcr Laboratory Developed Test For The Detection Of Pneumocystis Jirovecii In Bronchoalveolar Lavage Samples, Caitlyn Moon

Honors Scholar Theses

Pneumocystis jirovecii is an opportunistic, host-obligate fungal pathogen responsible for causing P. jirovecii pneumonia (PJP) in humans. PJP is treated with trimethoprim-sulfamethoxazole (TMP-SMX), a strong broad-spectrum antibiotic that carries risk of renal and hepatotoxicity. Therefore, rapid diagnosis or exclusion of PJP is crucial to ensure PJP-positive patients receive effective treatment and PJP-negative patients avoid unnecessary antibiotics. Unlike most microorganisms, P. jirovecii cannot be cultured, presenting complications for the typical methods of diagnosing fungal pathogens. Historically, the gold standard for diagnosis was direct microscopic examination with stains such as methenamine silver and calcofluor white, but this diagnostic technique requires highly skilled …

Play To Win: A Randomized Controlled Trial To Assess The Effects Of Play-Based Training On Upper Extremity Function In Children With Hemiplegia, Vivian London

Honors Scholar Theses

Hemiplegia, or paralysis of one side of the body, is the primary symptom of unilateral cerebral palsy, a subtype of cerebral palsy, the most common movement disorder in children. Standard of care is regular physical and occupational therapy to improve performance in bimanual activities, but conventional therapy can be expensive and draining for caregivers and children, so a need exists for a novel intervention that can take place at home and that is economical for families while being engaging for children. This thesis reports data from a subset of ten children seen as part of a randomized controlled clinical trial …

Undergraduate Nursing Students’ Reactions To Germ Exposure Based On The Big 5 Personalities, Elizabeth Macdonald

Honors Scholar Theses

Despite extensive didactic and clinical training, variability in adherence to infection prevention practices in undergraduate nursing students exists. Individual differences, such as personality, may help to explain this inconsistency. The purpose of this study was to examine the extent to which the Big Five personality traits were associated with self-reported pathogen mitigation or avoidance behavior in undergraduate nursing students. An online survey design was used with undergraduate nursing students. Participants were presented with scenarios depicting different pathogen exposures and asked to indicate their likelihood of engaging in pathogen mitigation behaviors. The Big Five personality traits were also assessed, and bivariate …

The Development Of A Crispr-Based Calibrated Functional Assay For Classifying Pathogenicity Of Msh2 And Msh6 Variants In Lynch Syndrome, Olivia N. Amodeo

Honors Scholar Theses

Lynch syndrome is a hereditary disease caused by the inheritance of a mismatch repair gene variant. Individuals with this condition are predisposed to cancer development, most commonly colorectal cancer. Current guidelines for variant classification are based on numerous evidence categories, including functional evidence. However, many novel clinical variants are not well characterized, and evidence is difficult to obtain if functional assays are not calibrated.

To address this, our lab created a calibrated functional assay that calculates an odds of pathogenicity score for MSH2 and MSH6 gene variants that can be used as evidence for classifying variants of uncertain significance. This …

Essays On Ai-Driven Analytics For Enhanced Healthcare Delivery: From Onset To Outcomes In Neurological Diseases Management, Gabriel Owusu

Theses and Dissertations

Chronic neurological diseases, particularly Alzheimer's disease and related dementias (ADRDs), pose mounting global healthcare burdens. Despite advances in AI and health information technologies, early detection, precise diagnosis, and effective caregiver support remain elusive. This dissertation proposes innovative AI-enabled analytical frameworks to address these challenges across the full ADRD continuum.

The first essay designs an explainable AI-enabled clinical decision support system (CDSS) using a graph neural network for early AD identification, evaluated through usability studies demonstrating improved risk awareness and clinical engagement. The second essay introduces MADT-RNN, a multi-level attention-based deep transfer recurrent neural network that fuses convolutional and recurrent architectures …

Agnikarma Therapy In Management Of Plantar Fasciitis (Vatakantaka): A Systematic Review Of Ayurvedic Case Reports, Karishma Sebastian, Nidhin John, Amanda Killeen

School of Podiatric Medicine - Student Research

Plantar fasciitis is a leading cause of heel pain, commonly affecting adults aged 40–60, characterized by microtears and inflammation of the plantar fascia.

Conventional treatments (NSAIDs, corticosteroids, orthotics, surgery) often provide incomplete relief or cause adverse effects.

In Ayurveda, plantar fasciitis corresponds to Vatakantaka, a Vata-dominant condition of the heel region (Khudukapradesha).

Agnikarma, a para-surgical Ayurvedic technique involving therapeutic thermal cauterization using heated metallic rods (Shalaka), is described for disorders involving ligaments, bones, and joints with chronic pain and stiffness.

This review synthesizes clinical case reports evaluating Agnikarma as a treatment for plantar fasciitis to determine its efficacy, safety, and …

Recommendations For Sharing Cardiovascular Implantable Electronic Device Data With Patients Based On Clinician Interviews, Carly Daley, Jonathan Shirazi, Tina Allmandinger, Mindy Flanagan, Stephanie Pruitt, Hung-Yeh Lin, Victor P. Cornet, Jeanne Carroll, Yi Rong Tan, Tammy Toscos, Michael Mirro

Health Services and Informatics Research

BACKGROUND Cardiovascular implantable electronic devices (CIEDs) capture an abundance of data that requires specific medical knowledge to interpret. Currently, there are no clear recommenda tions for sharing clinically meaningful CIED data with patients from the abundance of data in CIED remote monitoring reports.

OBJECTIVE The objectives of this study were to explore clinicians’ perceptions of clinical care gaps related to CIED data that could be improved through patient access to data and to generate recom mendations for sharing CIED data with patients.

METHODS In this institutional review board-exempt, 2-phase sequential qualitative study, 42 semi-structured phone interviews were conducted with 32 …

Eptinezumab In Treatment-Resistant Chronic Migraine: Four-Year Real-World Effectiveness And Treatment Persistence, Wan-Jen Hsieh, Kelly Nicol, Chai Ching Ng, Tsung-Wei Hou, Phillip Phan, Scott W. Keith, Brittany Heckel, Michael J. Marmura, Hsiangkuo Yuan

Department of Neurology Faculty Papers

AimTo evaluate 48-month real-world outcomes of eptinezumab users in chronic migraine (CM), including longitudinal effectiveness, treatment persistence, reasons for discontinuation, and post-discontinuation anti-calcitonin gene-related peptide (CGRP) treatment patterns.MethodsWe conducted a retrospective cohort study of 112 CM subjects initiating eptinezumab at a tertiary headache center between 2019 and 2021. Monthly headache days (MHD), migraine disability assessment (MIDAS), and average pain intensity (API) were extracted at baseline and every 6 months for up to 48 months using a predefined outcome form at each visit. Longitudinal changes were analyzed using generalized estimating equations (GEE) with an unstructured correlation matrix, adjusting for age, sex, …

Adventitial Macrophage Accumulation Impairs Perivascular Nerve Function In Mesenteric Arteries With Inflammatory Bowel Disease, Elizabeth A. Grunz, Benjamin W. Jones, Olubodun Michael Lateef, Sidharth Sen, Katie Wilkinson, Trupti Joshi, Erika M. Boerman

Biomedical Sciences

Introduction: Inflammatory bowel disease involves aberrant immune responses and is associated with both cardiovascular disease risk and altered intestinal blood flow. However, little is known about how inflammatory bowel disease affects regulation of perivascular nerves that mediate blood flow. Previous work found perivascular nerve function is impaired in mesenteric arteries with Inflammatory bowel disease. The purpose of this study was to determine the mechanism of impaired perivascular nerve function.

Methods: RNA sequencing was performed on mesenteric arteries from IL10−/− mice treated with H. hepaticus to induce disease (inflammatory bowel disease) or left non-gavaged (Control). For all other studies, Control and …

Improving Follow-Up After School-Based Dental Screenings Using Koha Data In Monterey County, Andre N. Edmond

Capstone Projects and Master's Theses

Limited follow-up after school-based oral health screenings is a major issue for young children in Monterey County, especially for those who do not have a regular source of dental care. This project focused on improving how screening data is used to connect students to needed services. The internship was completed with the Monterey County Oral Health Program and aimed to develop a better system for tracking KOHA (Kindergarten Oral Health Assessment) data and improving follow-up care for students identified with dental needs. Key activities included analyzing screening data, entering into a tracking system, and comparing results from different schools. The …

Impact Of Inhibiting Mitochondrial Calcium Uptake On Calcium Homeostasis And Postmortem Metabolism In Porcine Muscle, Fatema Rahaman Mishu

All Graduate Theses and Dissertations, Fall 2023 to Present

After harvesting the animal, pork muscle continues to undergo changes as it turns from muscle into meat. During this early period, the muscle uses up energy and produces acid, which lowers pH and can affect important quality traits such as color and how well the meat holds water. A key driver of these early changes is calcium, a natural mineral inside muscle cells that helps control contraction and energy use. In this study, we tested whether mitochondria (the cell’s “powerhouse”) help control calcium after harvest and, in turn, influence early postmortem changes in pork. We used a research compound (DS16570511) …

Evaluating The Impact Of Myplate-Based Expanded Food And Nutrition Education Program (Efnep) On Healthy Dietary Choices Among Low-Income Families, Theresa N. Agbonome

Electronic Theses, Projects, and Dissertations

Dietary behaviors towards healthy food choices remain a major public health issue in the United States, with prevalence among low-income families. The University of California Agriculture and Natural Resources (UCANR) with Expanded Food and Nutrition Education Program (EFNEP) trains both health educators and volunteers to provide community-based nutrition education, which prioritizes low-income families. The initiative employs the MyPlate guidelines that are composed of 5 different food groups which include fruits, vegetables, protein, grains, and dairy products. This project focuses on evaluating nutritional habits of disadvantaged families within San Bernardino County (SBC) by using an evidence-based evaluation tool known as the …

Development Of An Employee Leave Guide Handbook At The California University Of Science And Medicine, Leyal Nidal Fakhreddine

Electronic Theses, Projects, and Dissertations

Employee leave policies play an important role in supporting workforce well-being, organizational compliance, and retention of skilled labor, especially in medical and educational health institutions. However, employees still experience confusion when trying to make sense of complicated leave options such as the Family and Medical Leave Act (FMLA), maternity and paternity leave, and military leave. The lack of clear, centralized guidance can result in delays, miscommunication, and increased workplace stress.

This project was carried out as a part of the Master of Public Health (MPH) program integrative learning experience requirements at California State University, San Bernardino, and was conducted during …