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Full-Text Articles in Medicine and Health Sciences

Development Of A Midwifery Student Peer Debriefing Tool: An Interpretive Descriptive Study, Kate Buchanan, Carolyn Ross, Dianne Bloxsome, Jen Hocking, Sara Bayes Jun 2024

Development Of A Midwifery Student Peer Debriefing Tool: An Interpretive Descriptive Study, Kate Buchanan, Carolyn Ross, Dianne Bloxsome, Jen Hocking, Sara Bayes

Research outputs 2022 to 2026

Background: Psychosocial traumatisation associated with giving birth, can occur in those present with the woman giving birth, a phenomenon known as vicarious trauma. It has been identified that there are currently no interventions available for midwifery students who have experienced vicarious trauma following difficult birth experiences. Objective: To explore whether the counselling intervention developed by Gamble et al. (2005), can be adapted for midwifery students to be appropriately and feasibly used as a counselling intervention with peers who have experienced midwifery practice-related vicarious trauma. Design: Interpretive descriptive methodology. Setting: This study was set at two Australian universities from which pre-registration …


Identification Of Circrna Biomarkers In Osteosarcoma: An Updated Systematic Review And Meta-Analysis, Chunbin Zhou, Lois Balmer, Manshu Song, Gehendra Mahara, Kezhou Wu, Wei Wang, Hu Wang Jun 2024

Identification Of Circrna Biomarkers In Osteosarcoma: An Updated Systematic Review And Meta-Analysis, Chunbin Zhou, Lois Balmer, Manshu Song, Gehendra Mahara, Kezhou Wu, Wei Wang, Hu Wang

Research outputs 2022 to 2026

Circular RNAs (circRNAs) play a crucial role in cancer development and progression. This study aimed to identify potential circRNA biomarkers for osteosarcoma. Articles published from January 2010 to September 2023 were searched across eight databases to compare circRNA expression profiles in osteosarcoma and control samples (human, animal and cell lines). Meta-analysis was conducted under a random effects model. Subgroup analysis of circRNAs in different samples and tissues was performed. Diagnostic value was evaluated using receiver operator characteristic curves. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis explored functions of circRNA host genes. A circRNA-miRNA-mRNA axis …


Ocrelizumab In Multiple Sclerosis:Real-World Experience From Baluchistan, Pakistan, Ahmed Wali, Sajid Hameed, Hazar Khan, Amara Ahmed, Madiha Malik Jun 2024

Ocrelizumab In Multiple Sclerosis:Real-World Experience From Baluchistan, Pakistan, Ahmed Wali, Sajid Hameed, Hazar Khan, Amara Ahmed, Madiha Malik

Pakistan Journal of Neurological Sciences (PJNS)

Background and objective: Multiple sclerosis (MS) is an autoimmune demyelinating disorder affecting the central nervous system. Ocrelizumab, a disease-modifying drug for MS, is funded by Bait ul Maal Pakistan for economically disadvantaged patients in Balochistan. The objective of this study was to evaluate the treatment response of Ocrelizumab in our population.

Methods: This prospective observational study enrolled 22 patients from three tertiary care hospitals in Balochistan from July 2021 to June 2022. Patients aged 18–50 years diagnosed with MS and without contraindications for Ocrelizumab were included. The Expanded Disability Status Scale (EDSS) was calculated at baseline and at three, six, …


The Association Of Acute Stress And Single Leg Balance, Theodore W. Gehrig Iii Jun 2024

The Association Of Acute Stress And Single Leg Balance, Theodore W. Gehrig Iii

Loma Linda University Electronic Theses, Dissertations & Projects

Chronic low back pain is a widespread and expensive societal burden that is routinely near the top of the list of reasons people live with a disability. There is an undeniable connection between low back pain and psychological stress, and it has long been accepted that stress comes as a consequence of the burden of pain. Our group sought to determine if the inverse of this paradigm might be true: that stress may actually play a role in the etiology of low back pain through its influence on neuromuscular control and strategies for balance stability. In this dissertation, we include …


Effects Of Electrotherapy On Pain And Mobility, Pablo Mleziva Jun 2024

Effects Of Electrotherapy On Pain And Mobility, Pablo Mleziva

Loma Linda University Electronic Theses, Dissertations & Projects

Introduction: Neck chronic pain is one of the most common problems in people today. However, people do not always seek medical treatment for their pain. Subclinical or mild pain generally does not prompt people to seek medical treatment. Consequences of this type of pain can be anxiety, disability and proprioception problems. The American Physical Therapy Association (APTA) recommends transcutaneous electrical nerve stimulation (TENS) as an intervention to treat neck pain with mobility deficits. TENS for the treatment of pain has been used for many years; however, there is still an “efficacy-impasse” for the use of TENS despite half a …


E6 Inhibtion-Mediated Combinatorial Therapy For Hpv+ Hnscc, Sonia Whang Jun 2024

E6 Inhibtion-Mediated Combinatorial Therapy For Hpv+ Hnscc, Sonia Whang

Loma Linda University Electronic Theses, Dissertations & Projects

High-risk human papillomaviruses (HPV) are the causative agents of virtually all cases of cervical cancer and up to 80% of head and neck squamous cell carcinoma (HNSCC). Current treatment options include chemo- and radiotherapy, though the effectiveness of these therapies is limited by the viral oncoprotein E6, which disrupts apoptotic pathways by binding to and accelerating the degradation of molecules such as p53 and caspase- 8. Our hypothesis was that inhibiting E6 and rescuing the apoptotic mediators would increase the effectiveness of apoptotic agents. The aims of this study were to first, develop an HPV+ HNSCC xenograft model to test …


Effect Of Home Exercise Program On Visual Reliance For Balance In Older Adults, Madeha Jaber Jun 2024

Effect Of Home Exercise Program On Visual Reliance For Balance In Older Adults, Madeha Jaber

Loma Linda University Electronic Theses, Dissertations & Projects

Background: Older adults tend to rely excessively on visual inputs to maintain their balance. This overreliance on visual inputs can increase the risk of falls, particularly when visual inputs are reduced or eliminated. This study aimed to determine the effects of a home exercise program (HEP) on visual reliance for balance and cervical active range of motion (AROM) among older adults.

Patients/Materials and Methods: The study sample consisted of 19 older adults, aged 65-79 years old. Outcome measures included static balance, balance confidence, and cervical AROM. Participants were instructed to follow an 8-week HEP and were provided with …


Comparing Nurses’ Perceptions Of Work Environment And Health By Ethnicity, Nia M. Martin Jun 2024

Comparing Nurses’ Perceptions Of Work Environment And Health By Ethnicity, Nia M. Martin

Loma Linda University Electronic Theses, Dissertations & Projects

A healthy work environment significantly affects nurse outcomes such as burnout and retention, but also physical and mental health-- for nurses as well as for the patients for whom they provide care. Black/African Americans (BAAs) face numerous and unique challenges from systemic discrimination that contribute to health-related disparities and numerous physical and psychological challenges. Given the inherent challenges BAAs face and the need for supportive work environment for nurses, this study examined how ethnicity was associated with perceptions of work environment and personal health, focusing on BAA nurses to identify specific challenges and areas for improvement. This cross-sectional, descriptive correlational …


Why Do We Care About Safety With Tbi Patients?, Delaney Loring Rn Bsn, Haley Greenleaf Rn, Olivia Kaczmarek Rn Bsn, Michaela Ryerson-Wing Rn Jun 2024

Why Do We Care About Safety With Tbi Patients?, Delaney Loring Rn Bsn, Haley Greenleaf Rn, Olivia Kaczmarek Rn Bsn, Michaela Ryerson-Wing Rn

Nurse Residency

Do nurses working with acute and chronic TBI patients need additional education and training to provide safe, patient and family centered care during an inpatient hospital stay?


Subcutaneous Anticoagulation Administration Vs Ecchymosis, Ethan Langlois Rn Jun 2024

Subcutaneous Anticoagulation Administration Vs Ecchymosis, Ethan Langlois Rn

Nurse Residency

In adult patients receiving subcutaneous anticoagulation, how does using a slow injection time and local cold application compared to standard practice affect bruising?


Erdheim-Chester Disease Presenting In The Foramen Magnum With Mass Effect Of A 39-Year-Old Male, Joseph Fullmer, Brandon Metcalf, Casey Schukow Jun 2024

Erdheim-Chester Disease Presenting In The Foramen Magnum With Mass Effect Of A 39-Year-Old Male, Joseph Fullmer, Brandon Metcalf, Casey Schukow

Conference Presentation Abstracts

Background: Erdheim-Chester disease (ECD) is a rare clonal histiocytosis neoplastic condition. This condition is characterized by a non-specific infiltration of foamy macrophages in multiple organs, such as the bone or skeletal system (>95%), retroperitoneum, kidneys, and heart, resulting in inappropriate inflammation, fibrosis, and multi-end organ dysfunction. central nervous system (CNS) is present in a minority of cases. This condition is extremely rare with only a few hundred cases reported in medical literature. Methods: We present a case of ECD in a 39-year-old male with past medical history for type-2 diabetes mellitus, neuropathy, and low testosterone on replacement therapy who …


April / May / June 2024, Randy Curry, Cindy Brooks Jun 2024

April / May / June 2024, Randy Curry, Cindy Brooks

RURAL ROCKS

This is the April, May, and June issue of Rural Rocks from the SWOSU College of Pharmacy.


Measurement Invariance Of The Pandemic Anxiety Inventory In Different Demographic Groups, Irvin Sam Schonfeld, Tasmyn Prytherch, Mark Cropley, Jay Verkuilen, Renzo Bianchi Jun 2024

Measurement Invariance Of The Pandemic Anxiety Inventory In Different Demographic Groups, Irvin Sam Schonfeld, Tasmyn Prytherch, Mark Cropley, Jay Verkuilen, Renzo Bianchi

Publications and Research

Background The Pandemic Anxiety Inventory (PAI) was developed in the context of the COVID-19 pandemic. Its content allows it to assess anxiety in connection to any pandemic. Previous research has demonstrated the instrument’s reliability and validity. An important question for clinicians and researchers, however, remains open: Does the PAI have similar meaning for members of different demographic groups? The finding of measurement invariance would allow clinicians and researchers to comparatively assess pandemic-related anxiety across demographic groups, including favored and disfavored groups.

Methods We conducted a multi-group confirmatory factor analysis to assess the measurement invariance of the PAI using data obtained …


Postpartum Recovery After Severe Maternal Morbidity In Kilifi, Kenya: A Grounded Theory Of Recovery Trajectories Beyond 42 Days, Ursula Gazeley, Marvine Ochieng, Onesmus Wanje, Angela Koech, Grace Mwashigadi, Nathan Barreh, Alice Kombo, Mwanajuma Bakari, Grace Maitha, Marleen Temmerman Jun 2024

Postpartum Recovery After Severe Maternal Morbidity In Kilifi, Kenya: A Grounded Theory Of Recovery Trajectories Beyond 42 Days, Ursula Gazeley, Marvine Ochieng, Onesmus Wanje, Angela Koech, Grace Mwashigadi, Nathan Barreh, Alice Kombo, Mwanajuma Bakari, Grace Maitha, Marleen Temmerman

Centre of Excellence in Women and Child Health

Introduction The burden of severe maternal morbidity is highest in sub-Saharan Africa, and its relative contribution to maternal (ill) health may increase as maternal mortality continues to fall. Women’s perspective of their long-term recovery following severe morbidity beyond the standard 42-day postpartum period remains largely unexplored.

Methods This woman-centred, grounded theory study was nested within the Pregnancy Care Integrating Translational Science Everywhere (PRECISE) study in Kilifi, Kenya. Purposive and theoretical sampling was used to recruit 20 women who experienced either a maternal near-miss event (n=11), potentially life-threatening condition (n=6) or no severe morbidity (n=3). Women were purposively selected between 6 …


Articulatory Activity Of The Tongue, Jaw, And Lips During The Second Passaggio Transition Of The Soprano Voice, Richard C. Lissemore Jun 2024

Articulatory Activity Of The Tongue, Jaw, And Lips During The Second Passaggio Transition Of The Soprano Voice, Richard C. Lissemore

Dissertations, Theses, and Capstone Projects

This dissertation describes three experiments designed to explore the acoustic and articulatory activity of a perceptible change in the soprano voice known as the secondo passaggio, or second transition, which typically occurs for the [ɑ] vowel between D♮5 (587 Hz) and F♮5 (698 Hz). Acoustically, the transition involves a shift in resonance strategy from second resonance tracking of the second harmonic (fR2/2fo) to first resonance tracking of the fundamental frequency (fR1/fo). To quantify the acoustics of the transition, we employed the measure L1-L2, the …


Suture Fixation Of Traumatic Rib Fracture Flail Segment With Klebsiella Osteomyelitis., Krishna Patel, Anthony N Rizzo, John Bach, William Devoe Jun 2024

Suture Fixation Of Traumatic Rib Fracture Flail Segment With Klebsiella Osteomyelitis., Krishna Patel, Anthony N Rizzo, John Bach, William Devoe

Trauma and Acute Care Articles

We report the case of a 71-year-old male who initially presented with urosepsis and was found to have a rib fracture of his right 6th rib with a flail segment and an associated abscess. Given the concern for infection, surgical rib fixation with titanium plating was not pursued during the washout of his abscess and instead, he successfully underwent rib fracture stabilization with bilateral suture transfixation. He was continued on a prolonged course of antibiotics for Klebsiella pneumonia osteomyelitis and was discharged uneventfully with optimal pain control and adequate respiratory effort.


Evaluation Of Aluminum Exposure In Neonates Receiving Parenteral Nutrition, Emma Sedarski Jun 2024

Evaluation Of Aluminum Exposure In Neonates Receiving Parenteral Nutrition, Emma Sedarski

2024 Swedish Learning and Celebration Day

No abstract provided.


Naloxone: From Legislation To Distribution, Kailyn Elliot, Emily Stewart, John Delfeld Jun 2024

Naloxone: From Legislation To Distribution, Kailyn Elliot, Emily Stewart, John Delfeld

2024 Swedish Learning and Celebration Day

No abstract provided.


Study In A Day, Nicole Anderson, Laura Mcmakin, Quinton Gaspar Jun 2024

Study In A Day, Nicole Anderson, Laura Mcmakin, Quinton Gaspar

2024 Swedish Learning and Celebration Day

No abstract provided.


Safety And Efficacy Of Empiric De-Escalation Of Antibiotics For Pneumonia In The Intensive Care Unit, Brandon Carron Jun 2024

Safety And Efficacy Of Empiric De-Escalation Of Antibiotics For Pneumonia In The Intensive Care Unit, Brandon Carron

2024 Swedish Learning and Celebration Day

No abstract provided.


“Care For Me” Companion Cart, Helen Kelly, Kristofferson Yu, John Delfeld, Tom Thomas Jun 2024

“Care For Me” Companion Cart, Helen Kelly, Kristofferson Yu, John Delfeld, Tom Thomas

2024 Swedish Learning and Celebration Day

No abstract provided.


Between A Badge Buddy And A Policy, Sean Robinson Jun 2024

Between A Badge Buddy And A Policy, Sean Robinson

2024 Swedish Learning and Celebration Day

No abstract provided.


Polyvagal Theory For Kids: A Brain-Based Teaching Tool To Promote Coping, Katy Tenhulzen Jun 2024

Polyvagal Theory For Kids: A Brain-Based Teaching Tool To Promote Coping, Katy Tenhulzen

2024 Swedish Learning and Celebration Day

No abstract provided.


A Multisite Initiative To Increase Utilization Of Clinical Pathways In The Selection Of Systemic Cancer Treatment, Kate Hough Jun 2024

A Multisite Initiative To Increase Utilization Of Clinical Pathways In The Selection Of Systemic Cancer Treatment, Kate Hough

2024 Swedish Learning and Celebration Day

No abstract provided.


Safety Of Ketamine Use For Rapid Control Of Agitation In The Emergency Department, Rosa Hong Trieu Jun 2024

Safety Of Ketamine Use For Rapid Control Of Agitation In The Emergency Department, Rosa Hong Trieu

2024 Swedish Learning and Celebration Day

No abstract provided.


Impact Of Librarian-Mediated Literature Search Services, Frances Chu Jun 2024

Impact Of Librarian-Mediated Literature Search Services, Frances Chu

2024 Swedish Learning and Celebration Day

No abstract provided.


A Celebration Of Innovation And Discovery In Healthcare, Cara Gallegos Jun 2024

A Celebration Of Innovation And Discovery In Healthcare, Cara Gallegos

2024 Swedish Learning and Celebration Day

No abstract provided.


Iv Vs Po: The Acetaminophen Showdown At Swedish, Diem Pham, Adam Corson, Renee Rassilyer-Bomers Jun 2024

Iv Vs Po: The Acetaminophen Showdown At Swedish, Diem Pham, Adam Corson, Renee Rassilyer-Bomers

2024 Swedish Learning and Celebration Day

No abstract provided.


Neurocognitive Outcome Following Tuberculous Meningitis Treatment: A Systematic Review, Muhammad Ilham Dhiya Rakasiwi, Erlina Burhan, Afid Brilliana Putra, Ihya Fakhrurizal Amin, Nadhif Wiratara Jun 2024

Neurocognitive Outcome Following Tuberculous Meningitis Treatment: A Systematic Review, Muhammad Ilham Dhiya Rakasiwi, Erlina Burhan, Afid Brilliana Putra, Ihya Fakhrurizal Amin, Nadhif Wiratara

Pakistan Journal of Neurological Sciences (PJNS)

Background and objective: Tuberculous meningitis (TBM) is an infectious disease of the central nervous system that remains to be a global health challenge. Patients who survive after experiencing TBM have a risk of developing functional, cognitive and psychological disorders that can affect daily activities. The objective of this study is to present a comprehensive review of data on cognitive outcome after TBM infection.

Method: We conducted a systematic literature search to identify studies addressing cognitive outcomes in adult TBM patients. Following a systematic literature search (PubMed, Scopus, EBSCO), studies were reviewed by independent reviewers to assess eligibility for inclusion. Three …


Evaluation Of Body Mass Index (Bmi): A Risk Factor For Stroke Among Pakistani Youth, Shafaq Saleem, Safia Awan, Ibrar Rafique, Kashif Hafeez Jun 2024

Evaluation Of Body Mass Index (Bmi): A Risk Factor For Stroke Among Pakistani Youth, Shafaq Saleem, Safia Awan, Ibrar Rafique, Kashif Hafeez

Pakistan Journal of Neurological Sciences (PJNS)

Background and objective: Body Mass Index (BMI) has been recognized as a significant risk factor for stroke, especially among younger populations in South Asia. Rising obesity rates contribute to non-communicable diseases, with increased stroke incidences being observed in younger adults. The objective of this study was to assess BMI distribution among Pakistani youth across various educational levels, providing insight into obesity trends and potential health risks.

Methods: This cross-sectional study was conducted through an online platform, surveying 2,223 respondents across 38 cities in Pakistan. A semi-structured questionnaire was administered, covering 600 educational institutions. Participants were categorized by BMI using WHO …