Medicine and Health Sciences Commons^™

Esthetic Management Of Maxillary Anteriors With Complicated And Uncomplicated Fractures Using Different Fragment Reattachment Approaches, Lavanya A, Rajendra Kumar Tewari, Sharique Alam

Journal of Dentistry Indonesia

Appropriate management of anterior tooth fracture restores the function and aesthetics and provides a positive psychological impact for the patient. One of the most conservative approaches for such a restoration is reattachment; if a fracture fragment remains attached to the tooth and is available, as in young patients, immediate reporting helps preserve the vitality and long-term defense mechanism. Objective: This case report provides two cases with varied approaches for the management of complicated and uncomplicated crown fractures using reattachment procedures. Case report: During the clinical examination, the first case described the management of an uncomplicated fracture using the …

Resin-Build-Up As A Direct Monoblock Concept For Root Canal Dentin, Core, And Crown Restoration On Anterior Endodontically Treated Tooth, Citra Kusumasari, Takashi Hatayama, Junji Tagami, Yasushi Shimada Prof.

Journal of Dentistry Indonesia

The long-term clinical performance of restoration in endodontically treated teeth (ETT) is an essential yet complicated strategy to achieve it. A resin-build-up tooth with higher elastic moduli is a minimally invasive strategy to decrease the risk of catastrophic root fracture. Additionally, intracanal resin composite anchorage simplifies the restorative procedure and increases the bonding. Objective: This case report describes a resin-build-up tooth restoration using the direct monoblock concept to replace a failed metal post and core and porcelain fused to metal (PFM) crown on the maxillary right central incisor. Case report: A 50-year-old man attended a dental university hospital …

Developing An Ordered Logistics Regression Model For Denture Hygiene Among Elderly In Residential Care Homes, Wan Muhamad Amir W Ahmad, Ruhana Hasan, Mohamad Nasarudin Adnan, Farah Muna Mohamad Ghazali, Hazik Bin Shahzad, Nor Azlida Aleng, Mohamad Shafiq Mohd Ibrahim

Journal of Dentistry Indonesia

With a global aging population, the oral hygiene of elderly individuals in institutional settings requires unique management. Maintaining adequate denture hygiene is a critical aspect of their overall well-being, while neglecting denture hygiene can lead to various oral health issues, malnutrition, and further impacting their overall health. Objective: This paper aims to provide a preliminary overview of denture hygiene care among the elderly using an ordered logistics model. Methods: Data was obtained from 174 participants in two government institutional homes in Malaysia. The Principle Components Analysis (PCA) was used to identify significant variables and an ordered logistic model …

Peripheral Ameloblastoma Of Palatal Mucosa: A Rare Case Report And Literature Review, Filiz Namdar Pekiner, Suay Yağmur Ünal, Hakan Yülek, Gaye Keser

Journal of Dentistry Indonesia

Peripheral ameloblastoma (PA), an uncommon and unique form of odontogenic tumor, accounts for around 2-10% of all ameloblastomas. The extraosseous position is the distinguishing aspect of this form of tumor, which is otherwise comparable to a typical ameloblastoma. As late recurrence is also recorded, continuous follow-up is required. A case of peripheral ameloblastoma in a 23-year-old male that affected the right posterior palatal mucosa was presented in this case study. A 23-year-old male patient had an exophytic mass located at the junction of the hard and soft palate, in the palatal neighborhood of the tooth number 18. An excisional biopsy …

Minimally Invasive Treatment Of Molar Incisor Hypomineralization Without Using Burs: Experiences Via A Case Series In Vietnam, Võ Truong Nhu Ngoc, Nguyen Phương Huyen, Le Khả Anh, Phan Thi Thu Hang, Hoang Kim Loan, Ta Thành Dong

Journal of Dentistry Indonesia

Mild form of molar-incisor hypomineralization (MIH) on anterior teeth are posing great challenges to dental practitioners as it can have a huge aesthetic impact. In terms of deep MIH-related lesion below the healthy enamel, highly invasive methods for approaching the lesion body and removing the entire hypomineralized enamel using burs could lead to failures including aesthetic problems and even further tooth structure damage to the affected teeth. Case report: To resolve t his issue, we have proposed a modified resin infiltration technique based on the minimally invasive philosophy. In this study, we would like to report three specific cases …

Contents Of Vol. 31, No.2, August 2024, Dr. Yuniardini Septorini Septorini Wimardhani

Journal of Dentistry Indonesia

This is the Cover and the Contents of the Vol. 31 No. 2 2024

Leveraging The Science Of Early Life Predictability To Inform Policies Promoting Child Health, Laura M. Glynn, Sabrina R. Liu, Candice Taylor Lucas, Elysia Poggi Davis

Psychology Faculty Articles and Research

Addressing the tremendous burden of early-life adversity requires constructive dialogues between scientists and policy makers to improve population health. Whereas dialogues focused on several aspects of early-life adversity have been initiated, discussion of an underrecognized form of adversity that has been observed across multiple contexts and cultures is only now emerging. Here we provide evidence for “why unpredictability?”, including: 1. Evidence that exposures to unpredictability affect child neurodevelopment, with influences that persist into adulthood. 2. The existence of a translational non-human animal model of exposure to early life unpredictability that can be capitalized upon to causally probe neurobiological mechanisms. 3. …

Clinical Features Of Anterior Teeth Affected By Molar Incisor Hypomineralization And Treatment Experiences Using Transilluminated Light: A Cross-Sectional Study, Phạm Thanh Ha, Nguyễn Phương Huyen, Phạm Kim Thanh, Lương Minh Hang, Trần Tuấn Anh, Võ Như Trương Ngoc, Lê Khả Anh, Trần Anh Tuan, Tạ Thành Dong

Journal of Dentistry Indonesia

Classification and resin infiltration treatment of MIH-related permanent anterior teeth are increasingly receiving attention nowadays. Objective: The study aims to evaluate the characteristics of these teeth; and to assess factors regarding treatment. Methods: A cross-sectional study was conducted using transilluminated and reflected light photographs, and the lesion was classified according to its color, size, type, heterogeneity and surface integrity. The data were analyzed using a chi-square test and multivariate logistic regression analysis to evaluate enamel craze lines (ECL), post-eruptive breakdown (PEB), and treatment procedures. Results: 73 teeth from 46 patients were included, in which 53 teeth had been treated. Size …

Assessment Of Mandibular Incisive Canal And Anterior Loop In Cone Beam Computed Tomography In Vietnamese Mature Patients: A Retrospective Study, Anh Kha Le, Thao Phuong Tran, Tra Thu Nguyen, Loc Nguyen Gia Pham, Trung Thanh Nguyen, Viet Hoang Do

Journal of Dentistry Indonesia

Objective: This study aimed to assess the anatomical length of the mandibular incisive canal and anterior loop and the distance to surrounding structures. Methods: Our study was conducted on 70 cone beam computed tomography (CBCT) films of 70 Vietnamese adult outpatients (40 females, 30 males) at Hanoi Medical University, Vietnam. T-test was applied to assess the difference between the two sides and genders. Results: The mean length of the mandibular incisive canal (MIC) was 12.83 ± 5.13 mm. The anterior loop (AL) prevalence was 62.86%, with an average length of 2.37 ± 0.90 mm. The difference between the right and …

Single-Center Clinical Experience Of Extended Sleeve Lobectomy (Esl) Versus Standard Sleeve Lobectomy (Sl), Haoyou Wang, Wei Wang, Peng Zu, Gregor J Kocher, Mara B Antonoff, Alberto Lopez-Pastorini, Chenlei Zhang, Wei Chen, Hongxu Liu

Faculty, Staff and Student Publications

Background: Sleeve lobectomy (SL) and extended SL (ESL), which aim to preserve pulmonary function and enhance the quality of life of patients while ensuring oncological outcomes, are valuable surgical options for the treatment of centrally located non-small cell lung cancer (NSCLC). This study aimed to compare perioperative adverse events and long-term survival between SL and ESL in NSCLC patients, providing a comprehensive review of surgical outcomes, complications, and survival to assess the roles of SL and ESL in thoracic oncology.

Methods: This single-center retrospective study assessed the outcomes of NSCLC patients who underwent SL or ESL from June 2014 to …

Establishing A Model Predicting Gleason Grade Group Upgrading In Prostate Cancer., Jian Chen, Qiming Chen, Ze Wang, Xuzhi Yan, Yapeng Wang, Yao Zhang, Jun Zhang, Jing Xu, Qiang Ma, Peng Zhong, Dianzheng Zhang, Qiuli Liu, Weihua Lan, Jun Jiang

PCOM Scholarly Works

BACKGROUND: Gleason grade group (GG) upgrading is associated with increased biochemical recurrence (BCR), local progression, and decreased cancer-specific survival (CSS) in prostate cancer (PCa). However, descriptions of the risk factors of GG upgrading are scarce. The objective of this study was to identify risk factors and establish a model to predict GG upgrading.

METHODS: There were 361 patients with PCa who underwent radical prostatectomy between May 2011 and February 2022 enrolled. Univariate and multivariate logistic regression analyses were identified and nomogram further narrowed down the contributing factors in GG upgrading. The correction curve and decision curve were used to assess …

Regulatory Transposable Elements In The Encyclopedia Of Dna Elements, Alan Y Du, Jason D Chobirko, Xiaoyu Zhuo, Cédric Feschotte, Ting Wang

2020-Current year OA Pubs

Transposable elements (TEs) comprise ~50% of our genome, but knowledge of how TEs affect genome evolution remains incomplete. Leveraging ENCODE4 data, we provide the most comprehensive study to date of TE contributions to the regulatory genome. We find 236,181 (~25%) human candidate cis-regulatory elements (cCREs) are TE-derived, with over 90% lineage-specific since the human-mouse split, accounting for 8-36% of lineage-specific cCREs. Except for SINEs, cCRE-associated transcription factor (TF) motifs in TEs are derived from ancestral TE sequence more than expected by chance. We show that TEs may adopt similar regulatory activities of elements near their integration site. Since human-mouse divergence, …

Echocardiograms And Bed Placement In Patients With Multisystem Inflammatory Syndrome In Children, Hafsa Lodhi, Emma Singer, Mary Claire Mcglynn, Jinli Wang, Erik Hoefgen, Mythili Srinivasan, William B. Orr

2020-Current year OA Pubs

BACKGROUND: Understanding of multisystem inflammatory syndrome in children (MIS-C) continues to evolve with extensive evaluations, including echocardiograms, obtained in emergency departments (EDs) to assist with clinical decision making and bed allocation. We assessed the utility of obtaining echocardiograms in the ED to assist in determining bed placement for this patient population.

METHODS: This 2-year retrospective single-center study of patients 0-21 years old without underlying cardiac disease hospitalized for MIS-C focused on individuals whose initial evaluation occurred in the institution's ED and whose echocardiogram was obtained either in the ED or within 24 hours of admission. Patients were placed in two …

Loss Of Periostin Function Impairs Ligament Fibroblast Activity And Facilitates Ros-Mediated Cellular Senescence, Muhammad Farooq Rai, Xin Duan, Mingming Yan, Robert H Brophy, Lei Cai

2020-Current year OA Pubs

Anterior cruciate ligament (ACL) injuries pose a significant challenge due to their limited healing potential, often resulting in premature arthritis. The factors and mechanisms contributing to this inadequate healing process remain elusive. During the acute phase of injury, ACL tissues express elevated periostin levels that decline over time. The functional significance of periostin in ligament biology remains understudied. In this study, we investigated the functional and mechanistic implications of periostin deficiency in ACL biology, utilizing ligament fibroblasts derived from patients and a murine model of ACL rupture. Our investigations unveiled that periostin knockdown compromised fibroblast growth characteristics, hindered the egress …

Rare Right-Sided Posterolateral Diaphragmatic Hernia In An Adult Presenting As An Incarcerated Large Bowel Obstruction: A Case Report, Tanya J. T. Starr, Andrew G. Nicholson, Maximillian J. H. Starr, Jessica A. Traxler, Peter Y. Chu

HCA Healthcare Journal of Medicine

Introduction

A diaphragmatic hernia (DH) is a defect within a part of the diaphragm that allows intra-abdominal contents to enter the thoracic cavity. Diaphragmatic hernias can be congenital or acquired later in life. The most common congenital DH is the Bochdalek hernia (posterolateral hernia), but the most commonly acquired DH is due to traumatic injury. These hernias are rare in adults and are typically diagnosed incidentally. Surgical repair is the standard of care; however, data regarding the surgical approach is scarce. We report a case of a rare right posterolateral DH in an adult female patient who presented with acute …

Unveiling The Complexity Of Nocardia Septic Arthritis In An Immunocompromised Patient: A Case Report, Steven A. Kessler, Meghan R. Mansour, Ali Khreisat, Mamon Tahhan

HCA Healthcare Journal of Medicine

Background

Nocardiosis is the systemic manifestation of Nocardia infection, often found in immunocompromised individuals. Nocardia are transmitted via inhalation or skin wounds, disseminating hematogenously to organs and rarely, joints. We present a patient with immunosuppression who developed gout of the knee with superimposed Nocardial septic arthritis and a possible subsequent systemic infection.

Case Presentation

A 74-year-old man presented with left lower extremity swelling and pain. He was taking immunosuppressive medication for antineutrophilic cytoplasmic antibody-positive vasculitis. A week prior, an arthrocentesis test was positive for gout. He received prednisone without improvement. A repeat arthrocentesis was positive for Nocardia farcinica septic arthritis. …

Thrower’S Fracture With Subsequent Compartment Syndrome Requiring Emergent 2 Compartment Upper Extremity Fasciotomy, Andrew Wise, Darwin Ang

HCA Healthcare Journal of Medicine

Introduction

A thrower’s fracture is a mid-to-distal third humerus fracture that commonly presents as an audible pop with severe arm pain sustained during the throwing motion. Although thrower’s fracture has been described previously in the literature, this report is the first to demonstrate compartment syndrome as its potential sequel.

Case Presentation

A 25-year-old semi-professional pitcher presented to the emergency department with severe right arm pain following a pitch. He described hearing an audible pop with subsequent severe pain. He was found to have elevated compartment pressures in his upper arm and was rushed to the operating room for a 2 …

Idiopathic Granulomatous Lobular Mastitis: A Case Report, Wendy M. Timirau, Esra Sari, Maham Shahid, Nilmarie Guzman, Augusto Villegas

HCA Healthcare Journal of Medicine

Introduction

Idiopathic granulomatous mastitis (IGM), also known as nonpuerperal mastitis or granulomatous lobular mastitis, is a rare, benign, chronic inflammatory breast disease first characterized in 1972. IGM is characterized by sterile noncaseating lobulocentric granulomatous inflammation, usually affecting parous premenopausal women with a history of lactation.

Case Presentation

We present a 38-year-old African American woman presenting to our continuity clinic complaining of a painful right breast mass discovered during a self-breast examination. An initial right breast ultrasound demonstrated an area of concern with asymmetry, architectural distortion, and a questionable mass correlating to a 5.1 cm hypoechoic mass at the 12:30 position. …

The Placement Of A Single-Incision Mini-Sling For The Treatment Of Complete Intrinsic Sphincter Deficiency In An Adolescent Female: A Case Report, Norman Bebla, Dylan Gallegos

HCA Healthcare Journal of Medicine

Introduction

Intrinsic sphincter deficiency (ISD) is associated with a patient history of urethral injury or childbirth. Suburethral sling placement for ISD has been found to be beneficial in patients with this diagnosis. ISD in the pediatric population is rare and surgical management may prove difficult. ISD requires intensive counseling on available treatment options for this unique population.

Case Presentation

This report is on the use of the single-incision mini-sling for complete ISD in an adolescent patient. The patient was a 15-year-old nulligravid female who was found to have idiopathic complete intrinsic deficiency based on a multi-channel urodynamic study. Despite conservative …

Atypical Hemolytic Uremic Syndrome Following Influenza B: A Case Report, Kathryn E. Mcgraw, Amanda P. Porter, Alyssa M. Moffitt, Marina E M Golden, Heather Stewart

HCA Healthcare Journal of Medicine

Background

Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy that presents with a triad of hemolytic anemia, thrombocytopenia, and acute kidney impairment. It can be attributed to mutations in an array of different complement proteins leading to the overactivation of the complement system, the most impacted being the alternative pathway. Though rare, influenza B has been documented as a potential trigger to the development of aHUS.

Case Presentation

We discuss a 10-year-old girl with a history of aHUS who was found to have a repeat episode of aHUS following an influenza B infection. There have only been a few …

Clinical And Radiological Identification And Management Of Sapho Syndrome, Obyda Al-Housni, Jessica M. Alonso, Matthew Thornburg, Enny Cancio

HCA Healthcare Journal of Medicine

Introduction

Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is an autoinflammatory disease whose acronymic name stands for the symptoms commonly seen in the disease. These symptoms typically occur simultaneously, in different combinations, in patients during exacerbations of the disease. SAPHO syndrome is a rare disease, most frequently seen in patients aged 30 to 50. It is estimated to be found in 1 in 10 000 persons in White populations, with an even lower incidence seen in non-White populations.

Case Presentation

A post-menopausal woman with a medical history of SAPHO presented to the emergency department with left foot pain and …

Steroid-Dependent Recurrent Iga Vasculitis In A 19-Year-Old Woman, Hannah Berrett, Shivangi Gohil, Rebecca Kurian, Patricia Neyman

HCA Healthcare Journal of Medicine

Background

Immunoglobulin A (IgA) vasculitis is common in children and typically resolves spontaneously. However, when presenting in adults, it is more likely to be severe and recurrent.

Case Presentation

We present the case of a 19-year-old female patient with recurrent steroid-dependent IgA vasculitis. She had a history of a prolonged episode of IgA vasculitis in childhood. She presented to our hospital with proteinuria and a painful, palpable purpuric rash on her bilateral lower extremities. She was treated with high-dose intravenous steroids. When steroids were tapered, the patient had a recurrence of her painful rash. Over several months, she developed steroid-induced …

Man On The Mound: Pictures Of A Pitcher In Pain, Jean Medina, Matthew Campanella, Elliot Mendelsohn, Carl Mitchell, Murtaza Akhter

HCA Healthcare Journal of Medicine

Atraumatic ball thrower's humerus fracture is an uncommon, and poorly understood injury pattern. The majority of these cases are seen in untrained and younger individuals. A missed diagnosis could severely impact a patient's quality of life, as management is operative in most cases. Here, we present the case of a young patient, suffering an atraumatic "ball thrower's" fracture. We present images of this exceedingly rare injury pattern and showcase original artwork with a proposed mechanism of injury.

Characteristics Of Patients Hospitalized To Community Hospitals With Malignant Brain Tumors And Factors Associated With Discharge Destination, Se Won Lee, Thanapath D. Thantacheva, Denny Mack

HCA Healthcare Journal of Medicine

Background

Our main objective was to compare the characteristics and hospital outcomes of patients with primary and metastatic brain malignancies and to investigate the associated factors related to hospital outcomes.

Methods

We conducted a retrospective, cross-sectional study of 1628 patients with brain malignancies from 8 community hospitals between 2017 and 2022 who were identified using International Classification of Disease codes. A stepwise logistic regression was used to identify demographics and clinical characteristics associated with in-hospital mortality and home discharge.

Results

The median age was 65 years old, with 72.5% of patients having metastatic brain malignancies. After 7.2 days of hospital …

A Survey Of Post-Graduate Satisfaction With Orthopaedic Residency Training At A Single Institution, Jared L. Sain, Craig R. Louer, Robert J. Esther, Christopher W. Olcott

HCA Healthcare Journal of Medicine

Background

The Accreditation Council for Graduate Medical Education (ACGME) has called for self-study within residency programs. Post-graduate surveys allow the graduate to reflect upon their residency experience after years of autonomous practice. Despite their potential utility, a standardized assessment of residency training from the perspective of orthopaedic alumni does not exist. In this study, we aimed to create, analyze, and share with our alumni a post-graduate survey based on ACGME core competencies.

Methods

The survey was developed by full-time orthopaedic faculty and reviewed by a survey methodologist to ensure clarity and an ideal survey format. In May 2020, the survey …

A Post-Suicide Survey: The Perspective We Have Been Missing, Matthew Larsen, Cassandra Sauther, Ryan Sauther, Justin Solomon

HCA Healthcare Journal of Medicine

Background

Suicide is a major problem in the United States and in the state of Idaho. Prevention data are lacking for suicide primarily because information about those who completed suicide is not attainable. There are no published data from surveying the family members of the deceased. Our objective was to learn more about those who died by suicide by surveying family members or close contacts of the deceased.

Methods

We conducted a descriptive study using a 77-question survey to obtain information about those who died by suicide, with the survey being completed by their loved ones. Survey questions addressed the …

Management Targeted Genetic Evaluation Of An Idiopathic Neuropathy Cohort Through Attrv Amyloidosis Screening, Kristy A. Fisher, Santiago Diaz, Jeffrey Gelblum, Charles Brock, Niraja Suresh, Meghan Towne

HCA Healthcare Journal of Medicine

Background

While the reported prevalence of polyneuropathies is 1%-3%, the incidence of hereditary transthyretin amyloidosis in the United States is estimated to be 1 in 100 000 individuals. Polyneuropathies are known to be difficult to treat and lead to significant morbidity. The aim of pain management is symptomatic treatment, with varying approaches to progression prevention being based on the causative pathophysiology.

We assessed the prevalence of hereditary amyloid transthyretin variant (ATTRv) amyloidosis, a progressive autosomal dominant multisystem disease caused by the abnormal formation and extracellular deposition of transthyretin protein fibrils in various tissues, in an idiopathic polyneuropathy population by using …

A Pilot Physician Mentoring Program In A Large Hospital System, Crista C. Keller Md

HCA Healthcare Journal of Medicine

This article summarizes the development and implementation of a mentoring program designed to support and educate physicians new to practice in a large, outpatient hospital system. The program addresses organizational, operational, and financial elements of medical practice. Topics include efficiency and time management, coding education, leadership, and burnout. These topics are often not directly addressed in medical education, yet are crucial to physician well-being. The article describes the program structure, initial feedback, and recommendations for program replication and expansion.

A Clinical Review On Spinal Epidural Abscess: Epidemiology, Pathophysiology, Diagnosis, And Management For Emergency Medicine And Hospitalist Physicians, Madeline A. Guy, Jeffrey S. Guy

HCA Healthcare Journal of Medicine

Spinal epidural abscess (SEA), a critical surgical emergency, demands prompt recognition and intervention to prevent severe complications and fatalities. The incidence of SEA is notably increasing, particularly among individuals with diabetes, intravenous drug use, or a history of invasive spinal procedures. Although SEA can manifest through various clinical symptoms, the presence of its classic triad—back pain, fever, and neurological deficits—is noteworthy despite its occurrence in only 10% to 13% of cases. Identifying this triad is vital due to its high specificity for SEA, which is essential to guiding swift diagnostic and therapeutic actions in a condition where early intervention is …

An Acknowledgement To The Hca Healthcare Journal Of Medicine's Reviewers And Editors For The First Half Of 2024, Graig Donini, Bruce Deighton

HCA Healthcare Journal of Medicine

The HCA Healthcare Journal of Medicine would like to thank those behind the scenes who make this publication possible. Our journal would not be possible without the assistance of our peer reviewers, authors, and board members.