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Articles 43351 - 43380 of 325315
Full-Text Articles in Medicine and Health Sciences
Improving Maintenance Of Central Line Dressing To Reduce Risk Of Central Line-Associated Bloodstream Infections In An Acute-Care Setting, Kristi Gaskill, Kerry Wilder, Emily Sneed, Astrid J. Pujals, Kim Newman
Improving Maintenance Of Central Line Dressing To Reduce Risk Of Central Line-Associated Bloodstream Infections In An Acute-Care Setting, Kristi Gaskill, Kerry Wilder, Emily Sneed, Astrid J. Pujals, Kim Newman
HCA Healthcare Journal of Medicine
Background
Central line-associated bloodstream infections (CLABSI) increase morbidity, mortality, and healthcare costs. Central venous access device (CVAD) dressing integrity is critical to prevent CLABSI. From the First Quarter to the Third Quarter of 2023, CLABSI rates related to disruption in CVAD dressing integrity increased significantly at our facility. Despite the delivery of education, competency validation, and checklist implementation, CLABSI rates remained high, making this our top strategic priority.
The purpose of this quality improvement initiative was to determine if gum mastic adhesive and hemostatic powder would improve dressing integrity and decrease CLABSI rates related to disruption of central line dressings. …
Enhancing Patient Safety: The Role Of Interdisciplinary Teams In Reducing Blood Culture Contamination, Austin Patrick Eisenberg, Fady M. Awad, Brian Watson, Mohammed Faris
Enhancing Patient Safety: The Role Of Interdisciplinary Teams In Reducing Blood Culture Contamination, Austin Patrick Eisenberg, Fady M. Awad, Brian Watson, Mohammed Faris
HCA Healthcare Journal of Medicine
Background
Blood cultures are vital to diagnostic workups among many hospitalized patients, providing valuable information about bloodstream infections (BSIs), which cause roughly 250 000 deaths annually between North America and Europe. Despite advances in health care, blood culture contamination remains a substantial problem, with deleterious effects on patient mortality, patient and hospital costs, and microbial resistance. This article reviews the repercussions of blood culture contamination on the health care system and delineates evidence-based strategies to decrease contamination rates.
Methods
To reduce blood culture contamination rates, our health care facility undertook a quality improvement initiative. A task force was created, consisting …
Central Line-Associated Bloodstream Infection Reduction In Hemodialysis Patients Across 9 Hospitals And 3 States, Nicki Roderman, Kasadi Moore, Shandlie Wilcox, Jennifer Jellerson, Zoey Bridges
Central Line-Associated Bloodstream Infection Reduction In Hemodialysis Patients Across 9 Hospitals And 3 States, Nicki Roderman, Kasadi Moore, Shandlie Wilcox, Jennifer Jellerson, Zoey Bridges
HCA Healthcare Journal of Medicine
Background
This quality improvement project was initiated to reduce hospital-acquired catheter-associated bloodstream infections (CLABSI) in hospitalized patients receiving dialysis. A team dedicated to reducing hospital-acquired infections led the implementation of evidence-based interventions across all the included hospitals. This innovative approach demonstrated substantial enhancements in outcomes for patients on hemodialysis.
Methods
To enhance patient safety in patients receiving hemodialysis, new strategies were implemented, including (1) transitioning from a vendor model to an internal model, enabling dialysis program standardization, (2) empowering intensive care nurses with increased autonomy and ownership, (3) transitioning to a standardized dialysis machine, and (4) introducing chlorhexidine gluconate (CHG) …
A Randomized Controlled Trial Of 2% Chlorhexidine Gluconate Skin Preparation Cloths For The Prevention Of Surgical Site Infections In Adults Undergoing Spine Surgeries: Residual Reduction In Skin Bacterial Load For 4 Days, Elizabeth Card, Yaping Shi, Wuraola Adesinasi, Matt Shotwell, Nancy Wells, Elizabeth Hall, Joseph Cheng, Edward Sherwood
A Randomized Controlled Trial Of 2% Chlorhexidine Gluconate Skin Preparation Cloths For The Prevention Of Surgical Site Infections In Adults Undergoing Spine Surgeries: Residual Reduction In Skin Bacterial Load For 4 Days, Elizabeth Card, Yaping Shi, Wuraola Adesinasi, Matt Shotwell, Nancy Wells, Elizabeth Hall, Joseph Cheng, Edward Sherwood
HCA Healthcare Journal of Medicine
Background
Surgical site infections (SSI) result in increased morbidity and mortality, prolonged recovery, longer hospital length of stay for medication or possible additional surgeries, and escalated health care costs. The purpose of this randomized controlled trial was to compare SSI rates and overall skin flora burden between those using chlorhexidine (CHG) cloths versus soap and water preoperatively in the adult spine surgery population.
Methods
Subjects were randomized preoperatively to use 2% CHG cloths versus soap and water the night before and morning of surgery prior to the operation. A skin culture was obtained at enrollment prior to any cleansing, again …
Assessing The Effectiveness Of A Non-Punitive Fall Prevention Program, Nicki Roderman, Shandlie Wilcox, Cynthia Lang
Assessing The Effectiveness Of A Non-Punitive Fall Prevention Program, Nicki Roderman, Shandlie Wilcox, Cynthia Lang
HCA Healthcare Journal of Medicine
Background
Our single-center, quality improvement project evaluated the impact of a fall reduction plan while using a Just Culture Algorithm that included weekly fall reviews involving front line staff using a non-punitive structure. The project has shown successful results.
Methods
Prior to starting the program, data at this institution indicated falls were higher than the national fall rate of 3-5 per 1000 patient days. To achieve the goal of reducing the fall rate to below 3.1, an interdisciplinary fall committee was formed, consisting of nurses, nursing leaders, patient care technicians, pharmacists, and physical therapists. The committee operated in a non-punitive …
Inpatient Falls: Epidemiology, Risk Assessment, And Prevention Measures. A Narrative Review, Taylor Locklear, Jeannie Kontos, Callaham A. Brock, Alexander B. Holland, Rachel Hemsath, Anna Deal, Shannon Leonard, Carsten Steinmetz, Saptarshi Biswas
Inpatient Falls: Epidemiology, Risk Assessment, And Prevention Measures. A Narrative Review, Taylor Locklear, Jeannie Kontos, Callaham A. Brock, Alexander B. Holland, Rachel Hemsath, Anna Deal, Shannon Leonard, Carsten Steinmetz, Saptarshi Biswas
HCA Healthcare Journal of Medicine
Patient falls are a common inpatient dilemma and comprise the largest category of preventable adverse events in hospitalized patients. These events place a clinical burden on the patient, such as increased morbidity and reduced quality of life, in addition to an economic burden on the hospital system. Fall prevention strategies have the opportunity to decrease inpatient health care costs and length of stay. Several risk factors have been identified that contribute to inpatient falls and several strategies have been identified to minimize this risk. These risk factors are typically characterized as intrinsic and extrinsic factors. Intrinsic factors include characteristics such …
Nursing Informatics: The Vital Nursing Link Between Technology And Patient Care, Sherri L. Hess, Caryn Alper
Nursing Informatics: The Vital Nursing Link Between Technology And Patient Care, Sherri L. Hess, Caryn Alper
HCA Healthcare Journal of Medicine
Advances in technology offer additional health care tools to improve the health of patients and efficiencies for our clinicians in innovative ways. These technologies cover a huge variety of therapeutics, ranging from wearable devices, such as insulin pumps, to robotic-assisted surgeries. Nursing informatics is firmly embedded in the use of technology to improve nursing care and science. One of the most recent developments in nursing is the exploration of virtual nursing. This paper will present the past, current, and future projections for this unique blend of nursing art and science with cutting-edge technology.
Revitalizing Emergency Rooms Nationally: Strategies And Insights, Jeffin Dejanovich, Noah Zanville
Revitalizing Emergency Rooms Nationally: Strategies And Insights, Jeffin Dejanovich, Noah Zanville
HCA Healthcare Journal of Medicine
Throughout the United States, the post-COVID-19 pandemic period has been marked by profound disruption to health care operations, coordination, and care capacity. These disruptions have been especially serious in the emergency room (ER) setting. While intensely challenging, the post-pandemic period has also presented opportunities for health care systems to approach classic challenges facing the ER with fresh eyes. In this editorial, the authors discuss key strategies being used to help revitalize ERs nationally and reflect on future challenges and directions.
Infection Prevention: The Small But Mighty Teams In Health Care, E. Jackie Blanchard
Infection Prevention: The Small But Mighty Teams In Health Care, E. Jackie Blanchard
HCA Healthcare Journal of Medicine
Infection prevention is a team within health care facilities and systems whose members are vital to reducing and mitigating patient harm secondary to infectious disease. Infection preventionists are subject matter experts who reside in the quality department and are responsible for multiple areas beyond infectious disease spread. They assist nursing teams, employee health programs, and epidemiologists in decreasing the spread of illness. They are widely under-recognized, though they have a significant impact on the overall stability of the health care system and the communities they serve.
A Historical View Of Nursing Research At Hca Healthcare, Jane D. Englebright
A Historical View Of Nursing Research At Hca Healthcare, Jane D. Englebright
HCA Healthcare Journal of Medicine
HCA Healthcare has been a pioneer in evidence-based practice (EBP) in nursing for over 20 years. Nursing leaders overcame 2 major challenges, generating useful data to inform practice and disseminating EBP across their vast network. These challenges were overcome by using data outside the electronic health record (EHR) while advancing the standardization of data within the EHR. Standardizing data had a significant impact on nurse-led research, leading to improvements in patient outcomes and changes in practice including medication dispensing, patient fall reporting, and scheduling guidelines. This retrospective shares some of these important innovations in nursing practice.
The Future Of Nurse-Led Research: The Road Ahead, Sammie Mosier
The Future Of Nurse-Led Research: The Road Ahead, Sammie Mosier
HCA Healthcare Journal of Medicine
Nursing as a profession is full of innovation. From nurse-led research and new technology to emerging models of care, nurses continue to blaze trails and take steps to improve patient care. As one of the largest employers of nurses in the United States, HCA Healthcare has an obligation to produce research and evidence-based practices to pave the way for the future of nursing practice and potentially change how care is delivered. In this editorial, HCA Healthcare’s chief nurse officer describes her vision for the future of nurse-led research and examines how education, partnerships, and technology facilitate the road ahead for …
Inspiring And Supporting Nurses’ Scholarly Works Through A Special Issue Highlighting Nursing-Sensitive Indicators, Sammie Mosier, Elizabeth Card, Caryn Alper
Inspiring And Supporting Nurses’ Scholarly Works Through A Special Issue Highlighting Nursing-Sensitive Indicators, Sammie Mosier, Elizabeth Card, Caryn Alper
HCA Healthcare Journal of Medicine
Nursing represents the largest discipline in health care, with just over 5 million nurses in the United States, and the discipline is under increasing pressure to make evidence-based decisions in the delivery of patient care. This special issue of the HCA Healthcare Journal of Medicine can inspire and support nurses’ scholarly work with an eye to dissemination in peer-reviewed medical journals. This issue highlights nursing’s contributions to improving patient outcomes through nurse-sensitive indicators, with the hope of elevating the quality of tomorrow’s health care.
A Clinical Case Of A Right Eyelid Multilobulated Lesion: Invasive Sebaceous Carcinoma Masquerading As Chalazion, Tyler Van Auken, Erin Reese, Martin Nguyen, Reece Fletcher, Peyton Collias, David Webb
A Clinical Case Of A Right Eyelid Multilobulated Lesion: Invasive Sebaceous Carcinoma Masquerading As Chalazion, Tyler Van Auken, Erin Reese, Martin Nguyen, Reece Fletcher, Peyton Collias, David Webb
Marshall Journal of Medicine
Sebaceous carcinoma (SC) is a rare and aggressive malignancy of the sebaceous glands, most commonly arising from the eyelid. The general presentation of SC varies, resulting in delayed identification and frequent misdiagnosis. Clinicians should include SC in a differential diagnosis when a patient presents with an eyelid lesion. Undiagnosed and untreated SC can have detrimental outcomes; therefore, early diagnosis and treatment are imperative to decrease mortality and morbidity.
This is the case of a 71-year-old male referred by his primary care physician to the ophthalmologist for an inflamed, multilobulated lesion on his right upper eyelid. The patient was initially diagnosed …
Industrial Explosion Survival After Presenting To A Rural Hospital: A Case Report, Carol L. Wright Becker, Roger Tillotson, William Krantz, Brad End, Stephanie Rellick, Emily Nutter
Industrial Explosion Survival After Presenting To A Rural Hospital: A Case Report, Carol L. Wright Becker, Roger Tillotson, William Krantz, Brad End, Stephanie Rellick, Emily Nutter
Marshall Journal of Medicine
Explosions can lead to numerous injuries.1 Studies show that trauma mortality increases by 14% when patients are treated at rural hospitals compared to non-rural facilities.2 A 43-year-old male arrived at a rural hospital with injuries from an explosion, where only a single board-certified emergency physician was on duty. The patient's polytrauma was severe, resulting in bilateral orbital compartment syndrome and Cushing's triad. Remarkably, he survived these extensive injuries. Despite the limitations of rural healthcare, such as restricted equipment, medications, and longer transfer times, rural emergency physicians should remain optimistic and help guide future management. This high-acuity, low-frequency trauma …
Long-Term Survival After Metastatic Pancreatic Cancer, Joshua Keefer, Mark Cooper, Toni Pacioles, Amanda Arrington
Long-Term Survival After Metastatic Pancreatic Cancer, Joshua Keefer, Mark Cooper, Toni Pacioles, Amanda Arrington
Marshall Journal of Medicine
Pancreatic adenocarcinoma is an aggressive cancer with poor outcomes regardless of resection and treatment. The 5-year survival rate is less than 10%. Even with proper resection of the primary tumor, there remains a high likelihood of recurrence within 20 months. This is the case of a patient who was diagnosed with pancreatic adenocarcinoma 7 years ago. This patient underwent resection of the primary tumor along with chemotherapy and radiation. Two recurrences, located in the lung, have both been resected. This case highlights the importance of prompt resection and regular surveillance to monitor for additional metastases.
A Rare Case Of Visual Symptoms Due To Isotretinoin Therapy, Mouhannad Azzouz, Patrick Duffy, Safiyyah Nomani, Conner Funke
A Rare Case Of Visual Symptoms Due To Isotretinoin Therapy, Mouhannad Azzouz, Patrick Duffy, Safiyyah Nomani, Conner Funke
Marshall Journal of Medicine
Isotretinoin has been a long-standing medication used to treat acne, with a gradual increase in the dose during therapy. A typical treatment course lasts 4-6 months.1 It has been shown to inhibit sebaceous gland functioning and keratinization.2 The most common adverse effects include xerostomia, cheilitis, dry nose, and sun sensitivity. Less common adverse effects include itching, irritation, hair thinning, dry eyes, rash, muscle aches, and joint pain.2 There has also been reported increased depression and suicidality as a result of Isotretinoin treatment.2 Notably, the black box warning on Isotretinoin is in its potential to cause severe …
Standing Systolic Blood Pressure: Insights From Heartful Living, Anand Chockalingam
Standing Systolic Blood Pressure: Insights From Heartful Living, Anand Chockalingam
Marshall Journal of Medicine
No abstract provided.
A Geriatric Interprofessional Education Workshop: A Mixed Method Study, Patricia Watford, Meghan Hall, Colleen Hergott, Wanda Jirau-Rosaly, Shilpa Brown, Elena Wood, Nicole Rockich-Winston
A Geriatric Interprofessional Education Workshop: A Mixed Method Study, Patricia Watford, Meghan Hall, Colleen Hergott, Wanda Jirau-Rosaly, Shilpa Brown, Elena Wood, Nicole Rockich-Winston
Journal of Applied Disciplines
Interprofessional healthcare teams are essential for meeting the needs of our older population. To prepare for interprofessional collaboration, educational programs should offer opportunities for interprofessional education. We created a four-hour geriatric interprofessional workshop addressing cognition, macular degeneration, dysphagia, home safety, fall risk, and pharmacotherapy to examine student perceptions of working in interprofessional teams and their attitudes toward geriatric patients. Participants included 189 second-year medical (MD) students, 41 first-year occupational therapy (OT) students, and 36 second-year physical therapy (PT) students. We utilized a sequential explanatory mixed-method approach. Data analysis comprised descriptive statistics, paired t-tests for the pre/post surveys, and inductive content …
The Santa Clara, 2024-10-31, Santa Clara University
The Santa Clara, 2024-10-31, Santa Clara University
The Santa Clara
No abstract provided.
Medical School Watercooler Newsletter - October 31, 2024, Lindsay Hughes
Medical School Watercooler Newsletter - October 31, 2024, Lindsay Hughes
Watercooler Newsletter
This is the Thursday, October 31, 2024 edition of the Frederick P. Whiddon College of Medicine's newsletter -- Watercooler.
Contents include:
- Neonatology division expands with addition of Kasniya
- Boatright named assistance dean for medical education
- Art of Medicine set for Nov. 19
- BMS students earns poster award at CCTS symposium in Birmingham
- Dean's Tailgate welcomes students and alumni for Homecoming
A Rare Case Of Pulmonary Nocardiosis With Pseudomonas Aeruginosa Superinfection In An Immunocompromised Patient, Kevin Liu, Md, Samuel Shulimson, Do, Herbert Patrick, Md
A Rare Case Of Pulmonary Nocardiosis With Pseudomonas Aeruginosa Superinfection In An Immunocompromised Patient, Kevin Liu, Md, Samuel Shulimson, Do, Herbert Patrick, Md
Jefferson Health - Northeast Posters (formerly Aria Health Posters)
Introduction
Nocardiosis is an uncommon opportunistic infection with over two thirds occurring in those who are immunocompromised [1] or who have undergone solid organ transplants [2]. Here, we present a unique case of pulmonary Nocardiosis complicated by superimposed Pseudomonas infection.
Kajian Risiko Kesehatan Terkait Pajanan Benzene, Toluene Dan Xylene Pada Pekerja Kilang Minyak Pt. X, Putri Noer Halizah, Mila Tejamaya
Kajian Risiko Kesehatan Terkait Pajanan Benzene, Toluene Dan Xylene Pada Pekerja Kilang Minyak Pt. X, Putri Noer Halizah, Mila Tejamaya
National Journal of Occupational Health and Safety
Workers in oil and gas production units are at risk of exposure to chemical hazards. One of the ingredients in petroleum is volatile organic compounds (VOC), with examples of ingredients known for their toxicity being benzene, toluene and xylene. This study aims to assess health risks related to exposure to benzene, toluene and xylene of oil refinery workers at PT. X. This study will analyze personal exposure to inhalation routes from benzene, toluene and xylene chemicals using the Chemical Health Risk Assessment (CHRA) method from the Department of Safety and Health, Malaysia. The study results showed that the risk level …
Big Data Analysis On Indonesia’S Primary Care Pay-For Performance, Aditya Darmasurya, Ari Dwi Aryani, Rahmad Asri Ritonga, Rahma Anindita, Pranatawati Nur Tsani, Bayu Yudanto, Tedo Arya Trisnanto, Trisnasari Trisnasari
Big Data Analysis On Indonesia’S Primary Care Pay-For Performance, Aditya Darmasurya, Ari Dwi Aryani, Rahmad Asri Ritonga, Rahma Anindita, Pranatawati Nur Tsani, Bayu Yudanto, Tedo Arya Trisnanto, Trisnasari Trisnasari
Jurnal Ilmu Informasi, Perpustakaan, dan Kearsipan
In Indonesia’s social security program (JKN), there are more than 1,6 million visits in primary care providers each day. Indonesia's Social Security Administrative Body for Health (BPJS Kesehatan) manages the healthcare data recorded by the providers. In late 2019, the new Performance-Based Capitation (KBK) was introduced to primary care providers. They are assessed every month before the due for capitation payment. There are three indicators in the KBK scheme which are contact rate, non-specialty referral ratio, and proportion of PROLANIS disease management program members with controlled clinical outcome (PROLANIS indicator. This study analyzes data insights of KBK through big data …
How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton Ma, Lmsw, Simone Kabarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.
How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton Ma, Lmsw, Simone Kabarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.
Faculty Publications
Background: The concept of health literacy (HL) is constantly evolving, and social determinants of health (SDoH) have been receiving considerable attention in public health scholarship. Since a 1-size-fits-all approach for HL fails to account for multiple contextual factors and as a result poses challenges in improving literacy levels, there is a need to develop a deeper understanding of the current state of HL and digital health literacy (DHL) research. Objective: This study examined scholars’ conceptualization and scope of work focused on HL and DHL. Methods: Using a search string, investigators (N=2042) focusing on HL, DHL, or both were identified from …
How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? A Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton, Simon Kavarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent Rd, Mph, Cscs, Cissn, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.
How Do Scholars Conceptualize And Conduct Health And Digital Health Literacy Research? A Survey Of Federally Funded Scholars, Mayank Sakhuja, Brooks Yelton, Simon Kavarana, Lauren Schaurer, Jancham Rachel Rumthao, Samuel Noblet, Michelle Angelique Arent Rd, Mph, Cscs, Cissn, Mark M. Macauda Phd, Mph, Lorie Donelle Phd, Rn, Fcan, Daniela B. Friedman Ph.D.
Publications
Background: The concept of health literacy (HL) is constantly evolving, and social determinants of health (SDoH) have been receiving considerable attention in public health scholarship. Since a 1-size-fits-all approach for HL fails to account for multiple contextual factors and as a result poses challenges in improving literacy levels, there is a need to develop a deeper understanding of the current state of HL and digital health literacy (DHL) research.
Objective: This study examined scholars’ conceptualization and scope of work focused on HL and DHL.
Methods: Using a search string, investigators (N=2042) focusing on HL, DHL, or both were identified from …
Evaluating Viability, Developmental Competence, And Chromatin Configurations Of Cryopreserved Equine Oocytes, Tricia Adams
Evaluating Viability, Developmental Competence, And Chromatin Configurations Of Cryopreserved Equine Oocytes, Tricia Adams
LSU Doctoral Dissertations
Assisted reproduction technology and the use of specialized laboratories have increased in the horse breeding industry over the last decade. This expansion has highlighted the inability to routinely cryopreserve oocytes and preserve female genetics. Oocyte vitrification, a cryopreservation process, continues to be characterized as an experimental procedure in horses. The goal of this dissertation was to evaluate the viability, developmental competence, and nuclear structures of cryopreserved equine oocytes to illuminate potential areas of improvement in the vitrification process. Oocytes were collected from abattoir derived ovaries and exposed to either varying lengths of in vitro maturation (IVM) or pretreated with a …
The African Initiative For Bioinformatics Online Training In Neurodegenerative Diseases (Ai‐Bond): Investing In The Next Generation Of African Neuroscientists, Bernard Fongang, Biniyam A. Ayele, Yannick Joel Wadop Ngouongo, Emmanuel Epenge, Cyrille D. Nkouonlack, Wepnyu Y. Njamnshi, Xueqiu Jian, Muralidharan Sargurupremraj, Alice B. S. Nono Djotsa, Gladys Maestre
The African Initiative For Bioinformatics Online Training In Neurodegenerative Diseases (Ai‐Bond): Investing In The Next Generation Of African Neuroscientists, Bernard Fongang, Biniyam A. Ayele, Yannick Joel Wadop Ngouongo, Emmanuel Epenge, Cyrille D. Nkouonlack, Wepnyu Y. Njamnshi, Xueqiu Jian, Muralidharan Sargurupremraj, Alice B. S. Nono Djotsa, Gladys Maestre
School of Medicine Publications
Neurodegenerative disorders, including Alzheimer's disease and AD‐related dementias (AD/ADRD), pose significant challenges to health care systems globally, particularly in Africa. With the advances in medical technology and research capabilities, especially in next‐generation sequencing and imaging, vast amounts of data have been generated from AD/ADRD research. Given that the greatest increase in AD/ADRD prevalence is expected to occur in Africa, it is critical to establish comprehensive bioinformatics training programs to help African scientists leverage existing data and collect additional information to untangle AD/ADRD heterogeneity in African populations. The South Texas Alzheimer's Disease Research Center, with efforts from the National Institutes of …
Effects Of Supervised Exercise Therapy On Muscle Function During Walking In Patients With Peripheral Artery Disease, Cody P. Anderson, Iraklis Pipinos, Jason M. Johanning, Sara A. Myers, Hafizur Rahman
Effects Of Supervised Exercise Therapy On Muscle Function During Walking In Patients With Peripheral Artery Disease, Cody P. Anderson, Iraklis Pipinos, Jason M. Johanning, Sara A. Myers, Hafizur Rahman
School of Podiatric Medicine Publications
Background: Although supervised exercise therapy (SET) is a primary treatment for peripheral artery disease (PAD), the current literature is limited regarding the mechanisms contributing to increased walking distances, including how lower extremity muscle function is altered after SET. This study aimed to investigate the effects of SET on lower extremity muscle function during walking in patients with PAD. Methods: Twelve patients with PAD participated in a 6-month SET program consisting of three weekly exercise sessions (a total of 72 sessions) and adhered to the American College of Sports Medicine’s (ACSM) recommendations. Each session started with a 5 min warm-up of …
Nutritional Indicators Of Bone Nonunion: A Systematic Review, Eleanor Christianson, Margaret Thomas, Sheila Sprague, Jessica Rivera, Andrew Chapple, Robert Zura
Nutritional Indicators Of Bone Nonunion: A Systematic Review, Eleanor Christianson, Margaret Thomas, Sheila Sprague, Jessica Rivera, Andrew Chapple, Robert Zura
School of Medicine Faculty Publications
Background/Objectives: Bone nonunion remains a clinical challenge in orthopedic surgery with significant impacts on mental and physical wellbeing for patients. There are several previously established risk factors of nonunion that are connected to nutrition, but this has yet to be substantially explored. This review seeks to assess all studies that present associations between nutrition and nonunion to understand the potential for clinical relevance in nonunion prevention. Methods: Case–control and cohort studies comparing nonunion risk based on nutritional factors were gathered through PubMed in July 2024. Data were extracted with dual verification through Covidence and assessed for bias using the Newcastle–Ottawa …
A Large Scale Multi Institutional Study For Radiomics Driven Machine Learning For Meningioma Grading, Mert Karabacak, Shiv Patil, Rui Feng, Raj K. Shrivastava, Konstantinos Margetis
A Large Scale Multi Institutional Study For Radiomics Driven Machine Learning For Meningioma Grading, Mert Karabacak, Shiv Patil, Rui Feng, Raj K. Shrivastava, Konstantinos Margetis
Department of Medicine Faculty Papers
This study aims to develop and evaluate radiomics-based machine learning (ML) models for predicting meningioma grades using multiparametric magnetic resonance imaging (MRI). The study utilized the BraTS-MEN dataset's training split, including 698 patients (524 with grade 1 and 174 with grade 2-3 meningiomas). We extracted 4872 radiomic features from T1, T1 with contrast, T2, and FLAIR MRI sequences using PyRadiomics. LASSO regression reduced features to 176. The data was split into training (60%), validation (20%), and test (20%) sets. Five ML algorithms (TabPFN, XGBoost, LightGBM, CatBoost, and Random Forest) were employed to build models differentiating low-grade (grade 1) from high-grade …