Medicine and Health Sciences Commons^™

The Relationship Between Social Support And Patient Characteristics Among Young Women With Breast Cancer, Lisa Moses, Evrim Oral, Donna Williams

Journal of the Louisiana Public Health Association

Background: Breast cancer is the most frequently diagnosed cancer overall and the most frequently diagnosed cancer among women in Louisiana. From 2016-2020, female breast cancer accounted for 13.9% of all cancer diagnoses and 7.2% of all cancer deaths in Louisiana. Social support (SS) positively affects quality of life and positively affects survival rates following a breast cancer diagnosis. However, young women with breast cancer (YBCS) often have difficulty finding existing services meeting their family’s needs in systems focusing on older women with breast cancer. Methods: This study explored the relationship between total SS, emotional support (ES), tangible support (TS), affectionate …

Utilizing Prams To Examine Wic And Non-Wic Participants' Smoking Prevalences In Louisiana, Almetra Granger, Tyra Gross, Ty-Runet Bryant, Amy Thierry, Michael D. Celestin Jr.

Journal of the Louisiana Public Health Association

Background: Cigarette and electronic cigarette use before, during, or after pregnancy increases the chances of severe health risks for both the mother and child. Quitting leads to significantly better health outcomes. Women, Infants, and Children (WIC) clinics serve large numbers of pregnant, breastfeeding, and postpartum women, offering an excellent opportunity to address tobacco cessation. But few studies assess tobacco use, particularly electronic cigarette use, among WIC participants. This study examined the relationship between WIC status and maternal tobacco use. Methods: We analyzed WIC (n=315) and non-WIC (n=152) participants smoking data from the 2016-2018 Phase 8 Louisiana Pregnancy Risk Assessment Monitoring …

No-Self, No Problem: A Buddhist Approach To Self-Concept Obsessive-Compulsive Disorder, Adam Brandt, Laura Smestad

Journal of Faith Integration Counseling (JFIC)

While exposure and response prevention is an effective treatment for obsessive-compulsive disorder, it may not fully address the psycho-spiritual concerns of clients whose obsessive-compulsive disorder symptoms threaten and leave them in distress about their self-concept. This article addresses this problem by introducing the term self-concept obsessive-compulsive disorder and offering Buddhist psychology, a theoretical orientation based on the Buddhist principles of nonjudgment, mindfulness, and no-self as a useful framework to couple with traditional obsessive-compulsive disorder treatment.

Editorial To Advances In Minimally Invasive Spine Surgery, Gabriel C. Tender, George A. Crabill

School of Medicine Faculty Publications

No abstract provided.

World Delirium Wareness And Quality Survey In 2023- A Worldwide Point Prevalence Study, Heidi Lindroth, Keibun Liu, Laura Szalacha, Giuseppe Bellelli, Mark Von Den Boogaard, Gideon Caplan, Chi Ryang Chung, Muhammed Elhadi, Mohan Gurjar, Gabriel Heras-La-Calle, Magdalena Hoffman, Marie-Madlen Jeitziner, Karla Krewulak, Tanja Mailhot, Alessandro Morandi, Ricardo Kenji Nawa, Esther S. Oh, Marie Oxenboell Collet, Rebecca Von Haken, Peter Nydahl, For The Wdad Study Team

Publications

Background

Delirium, an acute brain dysfunction, is proposed to be highly prevalent in clinical care and shown to significantly increase the risk of mortality and dementia.

Objectives

To report on the global prevalence of clinically documented delirium and delirium-related clinical practices in wards caring for paediatric and adult patients in healthcare facilities.

Design

A prospective, cross-sectional, 39-question survey completed on World Delirium Awareness Day, 15 March 2023.

Participants

Clinicians or researchers with access to clinical data.

Main Outcome and Measure

The primary outcome was the prevalence of clinically documented delirium at 8:00 a.m. (4 h) and 8:00 p.m. (±4 h). …

Polygenic Risk Scores And Extreme Coronary Artery Calcium Phenotypes (Cac=0 And Cac≥1000) In Adults ≥75 Years Old: The Aric Study, Omar Dzaye, Alexander C Razavi, Zeina A Dardari, Frances M Wang, Yasuyuki Honda, Khurram Nasir, Josef Coresh, Candace M Howard-Claudio, Jin Jin, Bing Yu, Paul S De Vries, Lynne Wagenknecht, Aaron R Folsom, Ron Blankstein, Tanika N Kelly, Seamus P Whelton, Martin Bødtker Mortensen, Ziqiao Wang, Nilanjan Chatterjee, Kunihiro Matsushita, Michael J Blaha

Faculty, Staff and Student Publications

Background: Coronary artery calcium (CAC) is heterogeneous in older age and is incompletely explained by traditional atherosclerotic cardiovascular disease risk factors. The extremes of subclinical atherosclerosis burden are strongly associated with either a low or high 10-year risk of incident atherosclerotic cardiovascular disease, respectively. However, the genetic underpinnings of differences in arterial aging remain unclear. We sought to determine the independent association of 2 polygenic scores for coronary heart disease (CHD) with CAC in adults ≥75 years of age.

Methods: There were 1865 ARIC (Atherosclerosis Risk in Communities) participants who underwent genetic testing at visit 1 (1987-1989) and CAC scans …

Anti-Egfr Aptamer Exhibits Direct Anti-Cancer Effects In Nsclc Cells Harboring Egfr L858r Mutations, Brian J. Thomas, Sania Z. Awan, Trupti Joshi, Mark A. Daniels, David Porciani, Donald H. Burke

Biomedical Sciences

Non-small cell lung cancer (NSCLC) adenocarcinoma (LUAD) is a leading cause of death worldwide. Activating mutations in the tyrosine kinase domain of the oncogene epidermal growth factor receptor (EGFR) are responsible for ~10–50% of all LUAD cases. Although tyrosine kinase inhibitors (TKIs) have been effective in prolonging patient survival and quality of life, acquired resistance and disease progression are inevitable, presenting a clear unmet need for alternative or adjuvant therapeutics. Here we show that an anti-EGFR aptamer (EGFRapt) decreases viability and tumor growth of LUAD cell lines harboring the L858R ± T790M mutation in EGFR. Additionally, we elucidate …

Small And Long Non-Coding Rna Analysis For Humantrophoblast-Derived Extracellular Vesicles And Their Effect On The Transcriptome Profile Of Human Neural Progenitor Cells, Jessica A. Kinkade, Pallav Singh, Mohit Verma, Teka Khan, Toshihoko Ezashi, Nathan J. Bivens, R. Michael Roberts, Trupti Joshi, Cheryl S. Rosenfeld

Biomedical Sciences

In mice, the fetal brain is dependent upon the placenta for factors that guide its early development. This linkage between the two organs has given rise to the term, the placenta–brain axis. A similar interrelationship between the two organs may exist in humans. We hypothesize that extracellular vesicles (EVs) released from placental trophoblast (TB) cells transport small RNA and other informational biomolecules from the placenta to the brain where their contents have pleiotropic effects. Here, EVs were isolated from the medium in which human trophoblasts (TBs) had been differentiated in vitro from induced pluripotent stem cells (iPSC) and from cultured …

Preventing Migration Of Esophageal Silicone Covered Self-Expanding Metal Stent Using Dental Floss In A Pediatric Patient, Sofia Colon Guzman, Nadia Ibrahimi, Amornluck Krasaelap

Presentations

Temporary esophageal stents are an important and effective treatment for benign esophageal strictures, such as those caused by caustic ingestions. Fully covered self-expanding metal stents (FCSEMS) provide the benefit of continuous dilation pressure over longer periods of time compared to bougie or balloon dilation. However, stent migration is the most common complication and can be observed in up to 40% of patients, especially with FCSEMS and in refractory strictures. Typically, the stent is secured by using clips or suturing devices. However, we present a case where traditional methods of securing a stent were not possible due to the location of …

Impact Of Gut Microbiota And Its Metabolites On Immunometabolism In Colorectal Cancer, Madison Flory, Paloma Bravo, Asfaqul Alam

Markey Cancer Center Faculty Publications

Colorectal cancer (CRC) is highly prevalent, accounting for approximately one-tenth of cancer cases and deaths globally. It stands as the second most deadly and third most common cancer type. Although the gut microbiota has been implicated in CRC carcinogenesis for the last several decades, it remains one of the least understood risk factors for CRC development, as the gut microbiota is highly diverse and variable. Many studies have uncovered unique microbial signatures in CRC patients compared with healthy matched controls, with variations dependent on patient age, disease stage, and location. In addition, mechanistic studies revealed that tumor-associated bacteria produce diverse …

Exploring Body Composition And Sexual Behavior In South Texas College Students, Soyoung Kwon, Shannon Shen

Journal of Social, Behavioral, and Health Sciences

In this exploratory study, we examined the understudied relationship between body composition and sexual behavior among freshmen college students, addressing a gap in empirical research. Our sample consisted of 217 nonclinical college students recruited from a university in the southwestern United States; a majority of the students were Hispanic (70%) and freshmen (95%). Using multivariate logistic regression, we explored associations of body mass index, body fat percentage, and fat mass index with sexual behaviors. More than half of the participants were either overweight (22.5%) or obese (30.4%), and nearly 70% fell outside the healthy range of body fat. Results showed …

A Unilateral Myopic Shift Secondary To Sturge-Weber Syndrome Results In Refractive Amblyopia Of The Fellow Eye In A Pediatric Patient, Mckenzie Stewart, Christina Twardowski

Posters

A 4-year-old patient with unilateral glaucoma secondary to Sturge-Weber Syndrome causes a myopic shift. The fellow healthy eye maintains high hyperopia resulting in anisometropic refractive amblyopia, requiring occlusion therapy. It is well documented that a glaucomatous high IOP causes an expansion of the globe due to excessive plasticity of collagen fibers in pediatric eyes. The elongated axial length induces myopic shifts. In this patient, the myopic shift in her glaucomatous eye resulted in a unilateral high hyperopic refractive error in the fellow eye with normal ocular health. This anisometropia is enough to cause amblyopia in the hyperopic eye. In past …

Terminal Ileal Intubation In Retroflexion In A Pediatric Patient, Lakshmi Kunam, Antonia Fernandez Ovalle, Thomas M. Attard

Posters

Background: Terminal ileum (TI) intubation is integral to complete diagnostic ileocolonoscopy in children. It is necessary to determine terminal ileal involvement in patients with a broad spectrum of pathologic processes. In some cases the standard method of intubation does not lead to success and retroflexion is needed. Here we describe the case of terminal ileal intubation in retroflexion on a 14 year old female. Case description: 14 year-old female patient with a past medical history of chronic abdominal pain, NAFLD, anxiety, vulvovaginitis, lichen sclerosus, depression, constipation, delayed menses, and GERD who was admitted for 2 weeks of escalating symptoms and …

But, It's Just A Uti, Gillian Long

Posters

IgA Vasculitis is a commonly seen presentation in the pediatric population. The constellation of symptoms typically includes purpuric rash, joint pain, abdominal pain and hematuria. This 12 year old female was seen by her pediatrician for rash on her legs, shortness of breath, cough and night sweats that all started around 2 months ago. Additionally, a 25 pound weight loss was noted over the past year. The rash appeared as nonblanching purpura on her lower extremities, lending suspicion to IgA Vasculitis. She was first treated for UTI with cefuroxime, and then treated with steroids. Urinalysis showed persistent hematuria and she …

Deoxycholic Acid Injections As A Nonsurgical Treatment For Lipomas In Adiposis Dolorosa (Dercum Disease), Zvi Schwartz, Kayla Brockmeyer, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

Adiposis dolorosa (Dercum disease) is a rare condition characterized by diffuse and recurring painful lipomas on the trunk and extremities. Patients are typically middle-aged females with an elevated BMI presenting with chronic pain. Physical examination reveals soft subcutaneous nodules and masses, tender to palpation. The associated pain significantly impacts quality of life and requires therapeutic intervention. The most common treatment option is surgical excision. Alternative options should be considered for patients with numerous lipomas where surgical management is not practical or is not desired. Deoxycholic acid injections are a viable alternative non-surgical technique. We present a case of a 55-year-old …

Drug-Induced Subacute Cutaneous Lupus Erythematous From Cenobamate: Case Presentation And Review Of The Literature, Safiyyah Bhatti, Daniel Joffe, Timothy Webster, Jason Lee, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

A 68-year-old woman with a history of seizures on cenobamate presented with an itchy rash all over her body. The rash started about one month prior to her presentation to the dermatology clinic. The rash was initially treated with topical triamcinolone with improvement at one-month follow-up. However, four months later the rash flared and there was concern that cenobamate was the cause. Biopsy was performed showing vacuolar interface dermatitis with atrophy, suggestive of subacute lupus erythematosus. Blood work revealed positive antinuclear antibody, anti-ribonucleoprotein antibody, Sjogren Anti-SS-A and positive histone antibody. Given the worsening rash, positive labs, and cenobamate as the …

Addressing Barriers To Post-Graduate Research Training In Low Resource Settings: An Innovative Approach In An Institution Of Higher Learning In Kenya, Eunice Muthoni, Rosebella Iseme, Roselyter Riang’A, James Orwa, Ken Njenga, Anthony Ngugi

Population Health, East Africa

Background: Numerous barriers hinder health research training in Post-Graduate Medical Education Programs, especially in developing countries. Research training is pivotal for medical residency, providing essential knowledge and skills for dissertation completion, fostering evidence-based medical practice, and nurturing future independent clinical researchers. A holistic approach to research education is imperative to surmount these barriers. We describe here a dissertation-centric research curriculum, delivered longitudinally, an innovative strategy undertaken by Aga Khan University's Medical College in East Africa (AKU-MCEA) to deliver postgraduate research.

Methods: A review of AKU-MCEA post-graduate research methods curriculum was conducted based on implementing Departments' experience, institutional policies, and residency …

Contactless And Scalable Approaches For Human Health And Performance Sensing, Ngoc Doan Thu Tran

Dissertations and Theses Collection (Open Access)

Human health and performance sensing has been extensively studied, from physiology to mental health and movement analytics. However, typical approaches rely on invasive and contact sensors or require professional practitioners, limiting their scalability. For example, the gold standard for measuring heart rate is through an electrocardiogram (ECG), which requires multiple probes attached to the skin and is impractical for individuals with skin issues. Additionally, it typically needs to be performed in a hospital setting under the supervision of a trained cardiac physiologist. Depression detection often relies on the expertise of psychologists or psychiatrists. However, there is a shortage of these …

Synaptic Plasticity In The Injured Brain Depends On The Temporal Pattern Of Stimulation, Quentin S Fischer, Djanenkhodja Kalikulov, Gonzalo Viana Di Prisco, Carrie A Williams, Philip R Baldwin, Michael J Friedlander

Faculty, Staff and Students Publications

Neurostimulation protocols are increasingly used as therapeutic interventions, including for brain injury. In addition to the direct activation of neurons, these stimulation protocols are also likely to have downstream effects on those neurons' synaptic outputs. It is well known that alterations in the strength of synaptic connections (long-term potentiation, LTP; long-term depression, LTD) are sensitive to the frequency of stimulation used for induction; however, little is known about the contribution of the temporal pattern of stimulation to the downstream synaptic plasticity that may be induced by neurostimulation in the injured brain. We explored interactions of the temporal pattern and frequency …

Adverse Childhood Experiences And Hiv-Related Stigma: A Quantitative Survey Of Tanzanian Men, June 2019, Amandeep Kaur, Monique J. Brown Ph.D., Mph, Geoffrey K. Kangogo, Xiaoming Li Ph.D., Ivan E. Teri, Gaspar Mbita, Aima A. Ahonkhai, Donaldson F. Conserve

Faculty Publications

Experiencing adverse childhood experiences (ACEs) may impact personal opinions, attitudes, and judgments, which can further result in HIV-related stigma. HIV-related stigma consequentially may impact HIV preventive measures such as HIV testing, pre-exposure prophylaxis uptake, and condom use. The extent to which ACEs influence HIV-related stigma perception has not been well studied. Therefore, the study aimed to examine the association between ACEs and perceived and interpersonal HIV-related stigma among Tanzanian HIV-negative men. Quantitative survey data were obtained from the Tanzania STEP (Self-Testing Education and Promotion) project established in four wards: Mabibo, Manzese, Tandale, and Mwanyanamala. A total of 507 men responded …

Sexual Behavior Among Emerging Adults In Africa: A Systematic Review And Meta-Analysis, Stevenson Chea, Vincent A. Kagonya, Osman Abdullahi, Amina Abubakar, Souheila Abbeddou, Kristien Michielsen, Amin Hassan

Institute for Human Development, East Africa

Background: Estimates on sexual behavior (SB) among emerging adults (EmA) is varied in literature, which presents a challenge when designing targeted interventions. We aimed to summarize literature on prevalence and risk factors of SB among EmA in Africa.

Methods: A search for studies published in PubMed, Embase, and Psych Info by March 2023 was done. Studies involving EmA (18–25 years), conducted in Africa, and reporting 1 or more of 7 SBs were reviewed. Pooled prevalence estimates were summarized using forest plots. Heterogeneity in SB was explored. Risk factors were synthesized using a modified socioecological model.

Results: Overall, …

J Mich Dent Assoc November 2024

The Journal of the Michigan Dental Association

Each month, The Journal of the Michigan Dental Associationprovides news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. It stands as the primary publication reaching Michigan dentists. The November issue includes:

• Clinical Feature on discontinuation of lead apron use for dental radiology
• An introduction to the MDA Team and how they can be contacted to serve specific member needs
• A Back Page article on beginning practice and family
• Regular Departments: New Dentist Column, Updates on the MDA Foundation, MDA Services, Dentistry and the Law, Staff Matters

This month we welcome …

The New Professional: Starting A Practice Vs. Buying: What’S Right For You?, Amrita Patel Dds

The Journal of the Michigan Dental Association

This month's New Professional column explores the key decision of whether to start a new dental practice or purchase an existing one. Starting a practice offers flexibility in creating a brand and using the latest technology but requires building a patient base from scratch and managing upfront costs. Purchasing an existing practice provides immediate cash flow and an established patient base but requires more upfront investment and adapting to existing systems. Dentists should consider financial readiness, long-term goals, and work-life balance when making this decision.

Good Habits Are A Blueprint For Success!, Kathy Elias

Journal of the Macomb Dental Society

This article features a monthly column from the Macomb Dental Society's President, Dr. Kathy Elias.

I'M Mr. Brightside: Optimistic Dentistry Can Maintain Its Leadership Role In Dentist-Patient Decision-Making, Chester Gary D.D.S., J.D.

The New York State Dental Journal

Deceptive managed care tactics have violated the dentist-patient relationship and undermined trust in the dental profession.

The Courts Strike Back, Lance Plunkett Jd, Llm

The New York State Dental Journal

Issues of water fluoridation and noncompete agreements continue to undergo legal scrutiny, with no clear-cut answers in the offing.

Social Media Use By Dental Students In Dental Education, Ellen Lee D.D.S., Brian Chin M.B.A., Ningshu Lyu D.D.S., Yueqi Gao D.D.S.

The New York State Dental Journal

The purpose of this study is to evaluate dental student preferences for the use of social media in dental education. Our aim is to determine what students consider the best types of social media for dental education.

N Y State Dent J November 2024

The New York State Dental Journal

In the November 2024 issue, the reader will find the following feature articles:

• NYS Workers' Compensation & No-Fault Cases: The Good, the Bad, and the Ugly
• Social Media Use by Dental Students in Dental Education
• Guidelines for Interproximal Enamel Reduction (IPR)
• Exophytic and Focally Ulcerated Mass on the Mandibular Gingiva

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Reach Out When Help Is Needed, Michelle C. Dziurgot Dds

The Journal of the Michigan Dental Association

This editorial emphasizes the importance of recognizing signs of emotional distress, particularly in the dental field, where long work hours and patient stress can take a toll. It highlights the need for suicide prevention and awareness training, advocating for open communication and mental health support within work families.

The author shares a personal story of losing a colleague and stresses the value of the American Dental Association's Postvention Toolkit. The Michigan Dental Association’s Member Assistance Program is also recommended as a resource for mental health and emotional support.

The Back Page: Connection And Support: It’S A Family Thing, Kristen Kemmer Dds

The Journal of the Michigan Dental Association

In March 2023, the author welcomed her second daughter while managing the challenges of being a solo dental practice owner. With a supportive team, family, and a strong network of local dental colleagues, she successfully navigated maternity leave. Her dental team handled patient care seamlessly, and she leaned on friends and fellow practitioners for advice and emergency coverage. Online support and planning helped her manage financially, while collaboration within local dental groups ensured patient needs were met. The experience reinforced the importance of connection, support, and community in balancing motherhood and practice ownership.