Medicine and Health Sciences Commons^™

Does Lower Body Negative Pressure Have A Differential Effect On Blood Pressure And Blood Flow During Exercise In Women?, Jacob B. Sievers, Youanaa A. Gendy, Yusuf I. Rizk, Daisy Hernandez Valadez, Areum K. Jensen

International Journal of Exercise Science: Conference Proceedings

In response to central hypovolemia, triggered by lower body negative pressure (LBNP), women appeared to have lower tolerance compared to men. In addition, women exhibit blunted pressor responses to exercise compared to men, while cardiac output is increased in a similar fashion. Nonetheless, redistribution of blood flow from central to contracting muscles is required to meet higher metabolic demands during exercise in both men and women. Thus, we thought to investigate the differential effect of LBNP during exercise in men and women. PURPOSE: To determine the role of LBNP on redistributing blood flow from central to contracting muscles during moderate …

Case Study: Can Quadriceps Muscle Growth Be Achieved In Aclr Patient With Neuromuscular Inhibition?, Melody F. Anderson, Lee J Hinkle, Steven P. Allen, Aaron W. Johnson

International Journal of Exercise Science: Conference Proceedings

Despite extensive research of ACL reconstruction surgery (ACLR) and rehabilitation, mobility and functional issues often persist, leading to complications beyond the initial injury. This case study presents exercises employed to overcome negative consequences following ACLR. Participant (23yo, F, 163cm, 52kg) underwent ACLR in 2019 after a complete left ACL tear. After 7 months of PT following surgery, the participant was cleared to return to sport and continued consistent activity until 4 years post ACLR. At this time, the participant presented with knee pain, edema exacerbated by activity, 20% loss of range of motion (ROM), and extensive atrophy of the quadriceps …

Reduced Exertion High Intensity Interval Training (Rehit) On The Rowing Ergometer Elicits Lower Blood Lactate Accumulation And Higher Enjoyment And Affective Valence Versus Cycle Ergometry, Todd Anthony Astorino Ph.D, Rasmus Dahl Clausen

International Journal of Exercise Science: Conference Proceedings

Reduced exertion high intensity interval training (REHIT) is an extremely time-efficient version of sprint interval training requiring two to three 20 s “all-out” sprints within a 10 min exercise session. Findings from laboratories in the UK (Metcalfe et al. 2012) and Canada (Gillen et al. 2016) show significant increases in VO₂max, glycemic control, and body composition in inactive adults completing 6 - 12 wk of cycling based REHIT. A prior study (Astorino et al. 2020) in 85 adults having diverse VO₂max values shows positive affective valence despite substantial blood lactate (BLa) accumulation. Whether REHIT can be …

Differences In Muscle Activation In Individuals With Bilateral And Unilateral Chronic Ankle Instability Ankle Instability, Tanner Lee, Hyunwook Lee, Seunguk Han, Minsub Oh, Jon Tyson Hopkins

International Journal of Exercise Science: Conference Proceedings

Individuals with chronic ankle instability (CAI) have altered muscle activation. However, little is known about the differences in muscle activation of the lower extremity in individuals with bilateral and unilateral CAI. PURPOSE: To investigate differences in muscle activations during single-leg stance in individuals with bilateral and unilateral CAI. METHODS: Sixty participants were divided into 3 groups: 20 individuals with bilateral CAI (bilateral), 20 individuals with unilateral CAI (unilateral), and 20 healthy controls (control). Participants performed 3 trials of single-leg stance while muscle activations were recorded for 10 seconds. During the stance, participants stood with hands crossed on their …

Differences In Postural Control In Individuals With Bilateral And Unilateral Chronic Ankle Instability, Ethan Wood, Hyunwook Lee, Seunguk Han, Minsub Oh, Jon Tyson Hopkins

International Journal of Exercise Science: Conference Proceedings

Individuals with chronic ankle instability (CAI) have deficits in postural control and muscle activation. However, little is known about the differences in postural control in individuals with bilateral and unilateral CAI. PURPOSE: To compare postural control difference in individuals with bilateral and unilateral CAI. METHODS: Sixty participants were divided into three groups: 20 individuals with bilateral CAI (bilateral), 20 individuals with unilateral CAI (unilateral), and 20 healthy controls (control). Participants performed 3 trials of single-leg stance tasks for 10 seconds simultaneously. During the single-leg stances, participants were instructed to stand as still as possible on a force plate …

Effects Of Ankle Swelling On Dynamic Postural Control In Individuals With Chronic Ankle Instability, Isaiah K. Githuka, Hyunwook Lee, Seunguk Han, Minsub Oh, Jon Tyson Hopkins

International Journal of Exercise Science: Conference Proceedings

Chronic ankle instability (CAI) individuals have ankle swelling as a residual symptom. Joint swelling following musculoskeletal injuries inhibits full neural activation of muscles, known as arthrogenic muscle inhibition. However, little is known about the effects of ankle swelling on dynamic postural control in CAI individuals. PURPOSE: To investigate the effects of ankle swelling on dynamic postural control in CAI individuals. METHODS: A total of 45 participants were recruited from a university population: 15 CAI individuals with swelling (swelling), 15 CAI individuals without swelling (non-swelling), and 15 healthy controls (control). All participants were measured ankle swelling using a figure …

Effects Of Ankle Swelling On Static Postural Control And Patient-Reported Outcomes In Individuals With Chronic Ankle Instability, Ashton Earl, Hyunwook Lee, Seunguk Han, Minsub Oh, Jon Tyson Hopkins

International Journal of Exercise Science: Conference Proceedings

Chronic ankle instability (CAI) individuals have ankle swelling as a residual symptom. Joint swelling frequently occurs and inhibits full neural activation of muscles, known as arthrogenic muscle inhibition. However, little is known about the effects of ankle swelling on static postural control and patient-reported outcomes about ankle function and instability in CAI individuals. PURPOSE: To investigate the effects of ankle swelling on static postural control in individuals with CAI. METHODS: A total of 45 participants were recruited from a university population: 15 CAI individuals with swelling (swelling), 15 CAI individuals without swelling (non-swelling), and 15 healthy controls (control). …

Virtual Reality-Based Assessment On Static Postural Control Among Individuals With Chronic Ankle Instability, Copers, And Controls., Minsub Oh, Hyunwook Lee, Seunguk Han, Jon Tyson Hopkins

International Journal of Exercise Science: Conference Proceedings

Individuals with chronic ankle instability (CAI) have deficits in postural control. Previous studies assessing postural control have been limited by minimal environmental perturbation. Little is known about adding dynamic environments using virtual reality (VR) during static postural control in individuals with CAI. PURPOSE: To identify the effects of VR-based assessment on static postural control among individuals with CAI, copers, and healthy controls. METHODS: A total of 60 participants, including 20 individuals with CAI, 20 copers, and 20 healthy controls, performed 3 trials of a single-leg stance for 10 seconds with eyes open (EO), closed (EC), and VR. During the …

The Effect Of Gripping Handles On Knee Flexors And Extensors Force Production During The Isokinetic Strength Test, Christopher Hernandez, Mikayla Rudis, Lukas Krumpl, Nickolai Martonick, Youngmin Chun

International Journal of Exercise Science: Conference Proceedings

Understanding how gripping handles influence force production of knee extensors and flexors during different types of muscle contractions is crucial to obtain consistent isokinetic strength testing results. While it has been investigated the effect of gripping handles in the isometric and concentric contractions of the knee joint at various velocities, there is a lack of evidence of how gripping handles affectknee extensors and flexors in eccentric contraction. PURPOSE: This research was conducted to investigate the effect of gripping handles on the force production of the knee extensors and flexors during concentric, eccentric, and isometric contractions at various velocities. METHODS …

Identifying Predictors Of Fat Oxidation In Response To Exercise Prescribed According To Relative And Metabolic Intensities, Athrva Deshpande, Todd Astorino Ph.D

International Journal of Exercise Science: Conference Proceedings

Capacity for fat oxidation (FOx) is related to endurance performance and metabolic health. Chrzanowksi-Smith et al. (2021) revealed that maximal O₂ consumption (VO₂max), resting FOx, and physical activity level significantly predict maximal fat oxidation. PURPOSE: To identify predictors of the metabolic response to endurance exercise. METHODS: Active, non-obese men and women (N = 36, age and VO₂max = 24 ± 4 yr and 2.8 ± 0.8 L/min) underwent 3 sessions of cycling separated by 3 – 7 days. All bouts were performed at the same time of day within participants. Initially, body fat and fat-free …

Comparing Body Composition Measures In Us Army Soldiers, Kishani Kirubaharan-Smith, James R. Bagley, Kent A. Lorenz, Maria J. Veri

International Journal of Exercise Science: Conference Proceedings

The United States (US) Army currently uses circumference measurements (with body mass index, BMI) to estimate body fat (BF) composition in soldiers. While this current system is easy to administer, it has been shown to have poor validity compared to other modern body composition assessment techniques, such as air displacement plethysmography (BodPod). Specifically, circumference/BMI measures do not account for different body types, especially among female soldiers. PURPOSE: This study aimed to compare 1) body composition measures in US Army Soldiers (BF% via circumferences vs BodPod) and 2) differences in BF% between males and females. We hypothesized there would be significant …

Is There A Limit To Muscle Swelling After An Acute Resistance Training Session With Multiple Sets?, Rex Ruswick, Paulo H. Marchetti

International Journal of Exercise Science: Conference Proceedings

The number of sets per session and muscle group is an important RT variable responsible for the acute influence of cell swelling and chronic gains in muscle mass and strength. PURPOSE: The primary purpose of this study was to evaluate the acute effects of multiple sets on muscle thickness after an RT session in recreationally trained subjects. METHODS: Twenty-one resistance-trained subjects were recruited to this study (16 males and 5 females; age 24 ± 2.5 years, total body mass 75.1 ± 11.4 kg, height 171.7 ± 8.8 cm). During the first session, a ten repetitions maximum (10RM) test was applied …

Mobile-Health In Cardiac Rehabilitation: A Scoping Review Of Randomized Controlled Trials In Patients With Coronary Artery Disease, Theodore I. Nania, Rigdon C. Waite, Robert Scales

International Journal of Exercise Science: Conference Proceedings

Participation rates in cardiac rehabilitation (CR) remain low within the United States, which challenges practitioners to consider alternative models of healthcare delivery. A mobile-Health (m-Health) communication platform has the potential to augment traditional modes of CR delivery. PURPOSE: This investigation conducted a scoping review of randomized controlled trials (RCTs) that evaluated the effectiveness of m-Health delivered CR interventions in patients with coronary artery disease (CAD). METHODS: PubMed and Embase were searched using a custom search string, including keywords such as “coronary artery disease”, “cardiac rehabilitation”, “mobile application” and “digital health”. The author, title and abstract of all identified …

Relationship Among Bmi, Body Surface Area, Fluid Intake, And Sweat Rate On Elite Marching Arts Performers: A Pilot Study, Haydin C. Pazdur, Angela Haven A. Barandino, Miracle M. Busby, Daniela E. Ferreras, Theodore M. Locey, Michael M. Rodriguez, Christopher R. Hill, April Karlinsky, Jason Ng

International Journal of Exercise Science: Conference Proceedings

Elite groups of marching arts performers train at various intensities for long durations. They travel the country through a variety of climates, making hydration an important consideration. PURPOSE: The purpose of our pilot study was to evaluate the relationships between body mass index (BMI), body surface area (BSA), fluid intake, and sweat rate in elite marching arts performers. METHODS: We sampled 6 male and 1 female elite marching arts performers (mean ± SD; age: 20 ± 1 y, height: 177.0 ± 6.0 cm, body mass: 72.3 ± 9.1 kg). BMI was calculated by collecting height on a stadiometer and nude …

Anti-Cachexia Effect Of Polymorphonuclear Myeloid-Derived Suppressor Cell Depletion Therapy Is Not Present In Tumor-Bearing Mice Lacking T And B Cells, Hailey K. Gorman, Jonathan Specht, Michael Deyhle

International Journal of Exercise Science: Conference Proceedings

Polymorphonuclear (PMN) Myeloid-derived suppressor cells (MDSCs), are associated with poor cancer prognosis, partly due to their immunosuppressive effects on anti-cancer immunity. Cancer cachexia, characterized by debilitating skeletal muscle wasting, further reduces patient survival. Previously, antibody-mediated (anti-Ly6G) depletion of PMN-MDSCs attenuated skeletal muscle loss in mouse model of cancer cachexia. The mechanism by which PMN-MDSCs contribute to cachexia is unclear. Given the role that PMN-MDSCs play in supporting cancer disease progression depends on inhibiting anti-cancer adaptive immunity, we tested if the beneficial effects of PMN-MDSCs depletion on cachexia depend on the presence of adaptive immune cells. PURPOSE: We hypothesize that the …

The Effect Of Beetroot Juice Supplementation Dose On Neuromuscular Performance During Resistance Exercise, Raymond T. Gerardo, Isabella G. Lincoln, Keonabelle P. Paniagua, Justin M. Foster, Lauren E. Wideen, Nathan J. Ornelas, Isaac Tchaprazian, Jeffrey Li, Michael Egiazarian, Adam Pennell, Rachel Tan

International Journal of Exercise Science: Conference Proceedings

Nitrate-rich beetroot juice may have more pronounced ergogenic effects on exercise that requires high-power and high-velocity muscle contraction; however, the efficacy of, and the optimal dosing for nitrate to enhance resistance exercise performance is unknown. PURPOSE: To assess whether nitrate elicits dose-dependent ergogenic effects during a battery of resistance exercises in resistance-trained men. METHODS: Eighteen resistance-trained men were assigned in a randomized, double-blind, crossover design to consume 280 ml nitrate-depleted beetroot juice (PL; negligible nitrate), 70 ml nitrate-rich beetroot juice and 210 ml nitrate-depleted beetroot juice (BR-LOW; ~6.5 mmol nitrate), 140 ml nitrate-rich beetroot juice and 140ml nitrate-depleted …

No Sex Differences In Metabolic Responses To Submaximal Exercise, Alexander J. Macdonald, Alexander M. Anderson, Hanna Lauritzen, Ryan Pinter, Madison Mower, Todd Astorino Ph.D Facsm

International Journal of Exercise Science: Conference Proceedings

Tarnopolsky et al. (1990) showed significantly higher fat oxidation (FOx) in women versus men during endurance exercise, likely due to their higher concentrations of estrogen and type I muscle fibers. Prior studies support this stance (Venables et al. 2000), yet Wallis et al. (2006) showed no effect of sex on the metabolic response to exercise. PURPOSE: To compare substrate metabolism between men and women during submaximal exercise prescribed using metabolic (percent ventilatory threshold, %VT) and relative (percent maximal heart rate, %HRmax) intensities. METHODS: Healthy, non-obese men (n = 23) and women (n = 13) (age, % fat, and VO_{2 …}

Effect Of Daily Training On Hydration Status Of Elite Marching Arts Performers: A Pilot Study, Angela Haven A. Barandino, Miracle M. Busby, Daniela E. Ferreras, Theodore Locey, Haydin C. Pazdur, Michael Rodriguez, Christopher R. Hill, April Karlinsky, Jason Ng

International Journal of Exercise Science: Conference Proceedings

Every year, elite groups of of marching arts performers travel across the United States during the summer months of June through August, where they encounter different climates. Daily training for marching arts performers often takes place outdoors in the heat, but it is unclear what these individuals experience with regard to their hydration levels. PURPOSE: The purpose of this study was to investigate daily changes in hydration status among marching arts performers. METHODS: For this pilot investigation, we studied 3 men and 1 woman (mean ± SD; age: 20 ± 1 y, height: 174.1 ± 4.6 cm, body …

Correlation Between Pre-Exercise Hydration Status And Heart Rate Of Female Division Ii Collegiate Distance Runners During A Training Session, Daniela E. Ferreras, Alma I. Martinez, Cody M. Billings, Haydin C. Pazdur, Angela Haven A. Barandino, Robert Hernandez, Tamara Rodriguez, Christopher R. Hill, April Karlinsky, Jason Ng

International Journal of Exercise Science: Conference Proceedings

Female athletes participating in Division II collegiate sports are an understudied population. While athletes’ pre-exercise hydration status is known to have an important impact on a variety of performance metrics, it is unknown whether their pre-exercise hydration is associated with heart rate responses during a subsequent exercise bout. PURPOSE: The purpose of this study was to examine the correlation between pre-exercise hydration status and exercise heart rate (HR) of female distance runners on a Division II collegiate track and field team. METHODS: 8 female distance runners (Mean ± SD; age: 21 ± 1.8 y, height: 161.2 ± 10.8 cm, mass: …

Relationship Between Body Mass Index And Hydration Status In Air Force Rotc Cadets, Ivan P. Flores, Michael M. Rodriguez, Alma I. Martinez, Haydin C. Pazdur, Angela Haven A. Barandino, Christopher R. Hill, April Karlinsky, Jason Ng

International Journal of Exercise Science: Conference Proceedings

The Air Force Reserve Officer Training Corps (AFROTC) program prepares young individuals for their future as officers in the United States Air Force. This is a unique population because these cadets are college students who must maintain physical fitness through regular group exercise training. Previous research has identified that proper hydration is important to optimize training sessions. However, it is unknown whether the body size of this population is connected to their hydration status before and after exercise. PURPOSE: To examine the relationship between body mass index (BMI) and hydration status and the differences between BMI classifications of AFROTC cadets. …

Correlation Between Voluntary Fluid Intake And Sweat Rate Of Air Force Rotc Cadets During Outdoor Exercise, Michael M. Rodriguez, Alma I. Martinez, Haydin C. Pazdur, Angela Haven A. Barandino, Daniela Ferreras, Theodore M. Locey, Christopher R. Hill, April Karlinsky, Jason Ng

International Journal of Exercise Science: Conference Proceedings

The Air Force Reserve Officer Training Corps (ROTC) is a training program that gives individuals the opportunity to become leaders in and outside of the classroom while they prepare for their careers as officers in the United States Air Force or Space Force. This is a unique group of college students training to become tactical operators, which involves participating in regular group physical training. To optimize training, cadets should incorporate proper hydration strategies. Ideally, fluid intake volume should match sweat losses, however ROTC cadets’ hydration practices remain unclear. PURPOSE: The purpose of this study was to examine the relationship …

Relationship Between Exercise Intensity And Voluntary Fluid Intake In Air Force Rotc Cadets, Theodore M. Locey, Alma I. Martinez, Haydin C. Pazdur, Daniela E. Ferreras, Angela Haven A. Barandino, Christopher R. Hill, April Karlinsky, Jason Ng

International Journal of Exercise Science: Conference Proceedings

Air Force ROTC cadets are college students simultaneously receiving training to serve as officers in the United States Air Force. Regular group exercise is part of this training program, and good hydration habits would be conducive to optimizing the exercise sessions. However, it is unclear whether exercise intensity might influence this special population's voluntary drinking behaviors in a manner that is sufficient for optimizing exercise training sessions. PURPOSE: Therefore, the purpose of this study was to examine the relationship between exercise intensity and voluntary fluid intake in Air Force ROTC cadets during a typical training session. METHODS: Nine …

Impact Of Multifactorial Interventions With Medication And Lifestyle Optimization On Patients With Type 2 Diabetes: A Randomised Controlled Trial, Marwan M. El Deyarbi

Thesis/ Dissertation Defenses

The incidence of diabetes is increasing worldwide, consequently increasing mortality rates due to complications such as diabetic kidney disease. Clinical evidence on the protective effect of balanced diet, exercise and medication adherence with glucose-lowering intensification therapies on the progression of diabetes is insufficient, and interventions that are most effective in slowing cardiorenal metabolic complications in patients with type 2 diabetes mellitus (T2DM), especially in the UAE population diabetes remain to be elucidated. Several studies have shown that patient-related factors and limited medication adherence in patients with chronic diseases, are associated with poor clinical outcomes, long-term complications, and increased overall disease …

Self-Reported Fall Risk With The Stop Elderly Accidents, Deaths, And Injuries (Steadi) Questionnaire In An Early Outpatient Cardiac Rehabilitation Population, Daniel L. Enriquez, Jon Vimmerstedt D.O., Frank T. Paul Iii, Zeyu Song M.S., Bryan J. Taylor Ph.D., Facsm, Casey L. Filler M.S., Kaitlin E. Moore M.S., Molly C. Tomah M.S., Regis I. Fernandes M.D., Mike Studer Pt, Dpt, Fapta, Robert Scales Ph.D., M.S.

International Journal of Exercise Science: Conference Proceedings

An age-related decline in musculoskeletal health and physical function (PF) may contribute to frailty and lead to increased fall risk (FR). Traditional cardiac rehabilitation (CR) programs prioritize aerobic exercise conditioning with less emphasis on FR screening and prevention with related individualized PF training. PURPOSE: This study evaluated the prevalence of self-reported FR among patients enrolled in an early outpatient CR program. METHODS: Fifty-one adults (80% male; age 74.9 ± 6.7 years) agreed to complete the screening portion of the Center for Disease Control and Prevention (CDC) Stop Elderly Accidents, Deaths, and Injuries (STEADI) tool kit, which consisted of 12 …

Understanding The Impact Of Covid-19 On Yoga Instruction: Examining Teaching Methodology, Class Components, And Injury Patterns In The Northeastern Us, Sojung Kim, June Solow, Donald H Lein, Harshvardhan Singh

Rowan-Virtua School of Osteopathic Medicine Departmental Research

OBJECTIVES: This study aimed to examine the impact of COVID-19 on the perspectives of yoga instructors (YIs) regarding teaching methodology, class components, and yoga-related injuries among their clients DESIGN: A cross-sectional design in this study.

SETTING: A total of 407 YIs from Northeastern United States completed a customized, web-based survey.

MAIN OUTCOME MEASURES: Chi-square tests were carried out to determine changes in yoga teaching format before and during the pandemic, as well as the counts of yoga related injuries between face-to-face (FtoF) and online teaching format. Independent t tests were used to compare the characteristics of yoga teaching elements.

RESULTS: …

Multi-Omic Human Pancreatic Islet Endoplasmic Reticulum And Cytokine Stress Response Mapping Provides Type 2 Diabetes Genetic Insights., Eishani K Sokolowski, Romy Kursawe, Vijay Selvam, Redwan M Bhuiyan, Asa Thibodeau, Chi Zhao, Cassandra N Spracklen, Duygu Ucar, Michael L. Stitzel

Faculty Research 2024

Endoplasmic reticulum (ER) and inflammatory stress responses contribute to islet dysfunction in type 2 diabetes (T2D). Comprehensive genomic understanding of these human islet stress responses and whether T2D-associated genetic variants modulate them is lacking. Here, comparative transcriptome and epigenome analyses of human islets exposed ex vivo to these stressors revealed 30% of expressed genes and 14% of islet cis-regulatory elements (CREs) as stress responsive, modulated largely in an ER- or cytokine-specific fashion. T2D variants overlapped 86 stress-responsive CREs, including 21 induced by ER stress. We linked the rs6917676-T T2D risk allele to increased islet ER-stress-responsive CRE accessibility and allele-specific β …

What Makes An Effective Chief Of Pediatric Cardiology: Insights From Chiefs Of North American Pediatric Programs, Michael E. Kim, Wayne Franklin, Anne M. Dubin, Jeffrey J. Kim, Shubhayan Sanatani, R. Krishna Kumar, Shubhika Srivastava, Thomas R. Kimball, Mark Lewin, Joseph Rossano, Colin J. Mcmahon

Department of Medicine Faculty Papers

BACKGROUND: Although the position of a pediatric cardiology chief is often seen as the apex of one's academic career, its roles, responsibilities, and qualifications are not well defined in the literature. This study was done to gain further insight of the role and attributes of a pediatric cardiology chief by surveying those who are currently serving the position across North American centers.

METHODS AND RESULTS: This was a mixed-methods study with a survey given to North American pediatric cardiology chiefs at programs with fellowship training programs. The survey was a semistructured questionnaire that was independently reviewed by 3 cardiologists. Smaller …

Benchmarking Machine Learning Models To Predict Low Birthweight Baby Outcomes And Identify Associated Risk Factors From An Extremely Unbalanced Large-Scale Dataset, Yang Ren, Dezhi Wu, Yan Tong Ph.D., Ana Lopez-De Fede Ph.D., Sarah J. Gareau

Publications

Background: Low birthweight (LBW) is one of the leading causes of neonatal mortality in the United States (US), and also is a major causative factor of short- and long-term adverse health effects in newborns. To prevent adverse birth outcomes, it is critical to precisely predict and identify which mothers are at high risk of bearing LBW babies in the early stage of their pregnancy. Previous studies proposed various LBW prediction models from different ML algorithms primarily on small datasets. However, their model performance is significantly limited by data access barriers and data quality issues with one major technical challenge of …

The Association Of Individual Characteristics, Treatment Type, Treatment Satisfaction, Symptoms Of Pain And Fatigue With Health-Related Quality Of Life Among Adults With Gaucher Disease Type 1, Shauna L. Mangum

Nursing ETDs

People with rare disease have lower health-related quality of life (HRQoL) than the general population. Gaucher disease type 1 (GD1) is a rare, autosomal recessive, lysosomal storage disorder that affects multiple bodily systems. HRQoL improved with enzyme replacement and/or substrate reduction therapies, however, little is known about specific variables associated with HRQoL in GD1. This study explored associations between individual characteristics (gender, race, ethnicity, age, and genotype), treatment variables (treatment type, length of time on treatment, and treatment satisfaction) and symptoms of fatigue and pain with HRQoL among 97 adults with GD1. No significant associations were found among individual characteristics …

The Personality Profile And Leadership Style Of U.S. Vice President And 2024 Democratic Presidential Nominee Kamala Harris, Aubrey Immelman, Anne Marie Griebie, Elise Vomacka

Psychology Faculty Publications

The paper presents the results of an indirect personality assessment of U.S. vice president Kamala Harris, Democratic presidential nominee in the 2024 U.S. presidential election, from the conceptual perspective of personologist Theodore Millon.

Psychodiagnostically relevant data about Harris were collected from biographical sources and media reports and synthesized into a personality profile using the Millon Inventory of Diagnostic Criteria (MIDC), which yields 34 normal and maladaptive personality classifications congruent with DSM-III-R, DSM-IV, and DSM-5-TR.

The personality profile yielded by the MIDC was analyzed in accordance with interpretive guidelines provided in the MIDC and Millon Index of Personality …