Medicine and Health Sciences Commons^™

Evaluation Of Sirtuin 1 As A Predictor Of Cardiovascular Outcomes In Diabetic Patients With Limb-Threatening Ischemia, Federico Biscetti, Maria Margherita Rando, Maria Anna Nicolazzi, Enrica Rossini, Michele Santoro, Flavia Angelini, Roberto Iezzi, Luis H. Eraso, Paul J. Dimuzio, Dario Pitocco, Massimo Massetti, Antonio Gasbarrini, Andrea Flex

Department of Surgery Faculty Papers

Chronic limb-threatening ischemia (CLTI) significantly increases the risk of major adverse limb events (MALE) and major adverse cardiac events (MACE) after lower extremity revascularization (LER). This study aims to identify novel biomarkers that help to further reduce the risk of postoperative cardiovascular complications. In this prospective, nonrandomized, observational study, baseline serum levels of sirtuin 1 (SIRT1) were assessed in 147 diabetic patients scheduled for LER due to CLTI, and participants were followed for the occurrence of MALE and MACE over 12 months. Fifty-three patients experienced MALE, and 33 experienced MACE within the follow-up period. Lower baseline SIRT1 levels were significantly …

Caracterización Lingüístico-Discursiva De Los Mecanismos De Despersonalización Y Posicionamiento Del Autor En El Género Médico Ficha Clínica, David Sanchez-Jimenez, Paulina Meza

Publications and Research

El dominio de géneros especializados es una competencia que representa gran dificultad para los estudiantes en formación. Su falta de dominio puede impedir o retrasar el proceso de enculturación de un individuo en una comunidad. Para formar adecuadamente a los estudiantes en las prácticas discursivas disciplinares, son necesarios datos empíricos sobre las características lingüístico-discursivas de los textos que deben producir. El objetivo de esta investigación cualitativa es describir los recursos lingüístico-discursivos de despersonalización y posicionamiento del autor en el género médico Ficha clínica. El corpus está constituido por 52 Fichas clínicas producidas por estudiantes de medicina de una universidad chilena. …

Engaging Children In Conversations About Loss With The Help Of A Canadian Activity Book, Giulia Adele Dinicola

Journal of Social, Behavioral, and Health Sciences

In Canada, the practice of medically assisting patients in dying has been legal since 2016. Patients who have been diagnosed with serious diseases or disabilities—including mental illnesses, starting in March 2024—may meet the requirements to seek medically assisted suicide. As a result of this legalization, medical and ethical communities have expressed concerns regarding those who assist their loved ones in the process of dying. To date, little has been written about how children react when someone close to them decides to end their life due to unbearable suffering. In July 2022, the Canadian Virtual Hospice group published the Medical Assistance …

Test Smart, Treat Smart-Using Clinician Feedback To Adapt A Catheter-Associated Urinary Tract Infection Intervention For Spinal Cord Injury, Hilary Touchett, Kelley Arredondo, Casey Hines-Munson, Ivy Poon, Sally Ann Holmes, Barbara W Trautner, Felicia Skelton

Faculty, Staff and Students Publications

Background: Catheter-associated urinary tract infection (CAUTI) prevention is a major target for hospital quality metrics because it is linked to increased morbidity, mortality, and health care costs. Health care systems use strict protocols surrounding catheterization and maintenance, which often disregard the clinical needs of special populations (eg, spinal cord injury [SCI]). However, for populations that rely on chronic instrumentation of the bladder, asymptomatic (ie, nonpathogenic) bacterial colonization in the bladder is common but not linked to adverse outcomes. Additionally, alterations in neurologic and sensory function after SCI make it difficult for clinicians to discern asymptomatic bacteriuria from acute urinary tract …

Automatically Extracting Social Determinants Of Health For Suicide: A Narrative Literature Review, Annika M Schoene, Suzanne Garverich, Iman Ibrahim, Sia Shah, Benjamin Irving, Clifford C Dacso

Faculty, Staff and Students Publications

Suicide is a complex phenomenon that is often not preceded by a diagnosed mental health condition, therefore making it difficult to study and mitigate. Artificial Intelligence has increasingly been used to better understand Social Determinants of Health factors that influence suicide outcomes. In this review we find that many studies use limited SDoH information and minority groups are often underrepresented, thereby omitting important factors that could influence risk of suicide.

Normalization Of Cystic Fibrosis Immune System Reverses Intestinal Neutrophilic Inflammation And Significantly Improves The Survival Of Cystic Fibrosis Mice, Callie E. Scull, Yawen Hu, Scott Jennings, Guoshun Wang

School of Medicine Faculty Publications

BACKGROUND & AIMS: Cystic fibrosis (CF) is an autosomal recessive genetic disorder, affecting multiple organ systems. CF intestinal disease develops early, manifesting as intestinal bacterial overgrowth/dysbiosis, neutrophilic inflammation, and obstruction. As unresolvable infection and inflammation reflect host immune deficiency, we sought to determine if the CF-affected immune system plays any significant role in CF intestinal disease pathogenesis. METHODS: CF and sibling wild-type (WT) mice underwent reciprocal bone marrow transplantation. After immune reconstitution, their mortality, intestinal transit, fecal inflammatory markers, and mucosal immune cell composition were assessed. Moreover, reciprocal neutrophil transfusion was conducted to determine if neutrophil function affects intestinal movement. …

E-Cigarette Switching And Financial Incentives To Promote Combustible Cigarette Cessation Among Adults Accessing Shelter Services: A Pilot Study, Munjireen Sifat, Adam C. Alexander, Michael S. Businelle, Summer G. Frank-Pearce, Laili Kharazi Boozary, Theodore L. Wagener, Jasjit S. Ahluwalia, Darla E. Kendzor

Department of Medical Oncology Faculty Papers

Background: Smoking prevalence among U.S. adults experiencing homelessness is ≥70 %. Interventions are needed to address persisting tobacco disparities.

Methods: Adults who smoked combustible cigarettes (CC) daily (N=60) were recruited from an urban day shelter and randomly assigned to an e-cigarette switching intervention with or without financial incentives for carbon monoxide (CO)-verified CC abstinence (EC vs. EC+FI). All participants received an e-cigarette device and nicotine pods during the first 4 weeks post-switch; and those in the EC+FI group also received escalating weekly incentives for CC abstinence during the same period. Key follow-ups were conducted at 4- and 8-weeks …

High Incidence And Geographic Distribution Of Cleft Palate In Finland Are Associated With The Irf6 Gene, Fedik Rahimov, Pekka Nieminen, Priyanka Kumari, Emma Juuri, Tiit Nikopensius, Kitt Paraiso, Jakob German, Antti Karvanen, Mart Kals, Abdelrahman G Elnahas, Juha Karjalainen, Mitja Kurki, Aarno Palotie, Estonian Biobank Research Team, Finngen, Arja Heliövaara, Tõnu Esko, Sakari Jukarainen, Priit Palta, Andrea Ganna, Anjali P Patni, Daniel Mar, Karol Bomsztyk, Julie Mathieu, Hannele Ruohola-Baker, Axel Visel, Walid D Fakhouri, Brian C Schutte, Robert A Cornell, David P Rice

Faculty, Staff and Student Publications

In Finland, the frequency of isolated cleft palate (CP) is higher than that of isolated cleft lip with or without cleft palate (CL/P). This trend contrasts to that in other European countries but its genetic underpinnings are unknown. We conducted a genome-wide association study in the Finnish population and identified rs570516915, a single nucleotide polymorphism highly enriched in Finns, as strongly associated with CP (P = 5.25 × 10-34, OR = 8.65, 95% CI 6.11-12.25), but not with CL/P (P = 7.2 × 10-5), with genome-wide significance. The risk allele frequency of rs570516915 parallels the regional variation of CP prevalence …

Management Of Aorto-Right Ventricular Fistulas After Tavr, Ricardo Chia, Chamaka Kalutota, Kerry Cao, Steven Douedi, William Chang, Dominic Pinciotti, Mohammad Beizaeipour, Jennifer Joiner, Daniel Ice, Ronald Ross, Richard Kovach, Chunguang Chen, Muhammad Raza

Division of Cardiology Faculty Papers

This clinical case series reviews the diagnosis and management of aorto-right ventricular fistulas post-transcatheter aortic valve replacement, highlighting 3 cases. We emphasize early detection, individualized treatment strategies, and the role of multidisciplinary heart teams in achieving favorable outcomes. Comprehensive imaging and procedural planning are crucial for successful intervention and management of this rare complication.

Lactobacillus Rhamnosus Modulates Murine Neonatal Gut Microbiota And Inflammation Caused By Pathogenic Escherichia Coli., Hao Xuan, Shahid Umar, Cuncong Zhong, Wei Yu, Ishfaq Ahmed, Joshua Wheatley, Venkatesh Sampath, Susana Chavez-Bueno

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Pathogenic Escherichia coli strains produce neonatal septicemia after colonizing the neonatal gut. While the probiotic Lactobacillus rhamnosus GG (LGG) effectively reduces neonatal sepsis, LGG's effects on the neonatal intestinal microbiota alterations and inflammation triggered by E. coli are incompletely understood. We hypothesized that LGG significantly modulates the specific neonatal gut microbial populations changes and the inflammatory response elicited by the enteral introduction of septicemia-producing E. coli. To test this hypothesis, newborn rats were pretreated orally with LGG or placebo prior to infection with the neonatal E. coli septicemia clinical isolate SCB34. Amplicon 16S rRNA gene sequencing was performed on …

Skn-1 Activation During Infection Of Caenorhabditis Elegans Requires Cdc-48 And Endoplasmic Reticulum Proteostasis, Carolaing Gabaldón, Ozgur Karakuzu, Danielle A Garsin

Faculty, Staff and Student Publications

During challenge of Caenorhabditis elegans with human bacterial pathogens such as Pseudomonas aeruginosa and Enterococcus faecalis, the elicited host response can be damaging if not properly controlled. The activation of Nrf (nuclear factor erythroid-related factor)/CNC (Cap-n-collar) transcriptional regulators modulates the response by upregulating genes that neutralize damaging molecules and promote repair processes. Activation of the C. elegans Nrf ortholog, SKN-1, is tightly controlled by a myriad of regulatory mechanisms, but a central feature is an activating phosphorylation accomplished by the p38 mitogen-activated kinase (MAPK) cascade. In this work, loss of CDC-48, an AAA+ ATPase, was observed to severely compromise SKN-1 …

Successful Transcatheter Mitral Valve Mass Extraction With Complete Resolution Of The Severe Mitral Regurgitation, Hussam Al Hennawi, Ahmad Abulshamat, Shaurya Srivastava, Mohammed Qintar

Abington Jefferson Health Papers

Interest has arisen in exploring the off-label application of left-sided percutaneous mechanical aspiration, where conventional management strategies may not suffice. Percutaneous mechanical aspiration has been shown to be effective as a diagnostic and therapeutic intervention in select patients with infective endocarditis. This paper hereby reports the first case of a successful transeptal large bore manual aspiration device (AlphaVac; Angiodynamics) for nonbacterial thrombotic endocarditis with total resolution of associated severe mitral valve regurgitation.

Engineered Self-Regulating Macrophages For Targeted Anti-Inflammatory Drug Delivery, Molly Klimak, Amanda Cimino, Kristin L Lenz, Luke E Springer, Kelsey H Collins, Natalia S Harasymowicz, Nathan Xu, Christine T N Pham, Farshid Guilak

2020-Current year OA Pubs

BACKGROUND: Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by increased levels of inflammation that primarily manifests in the joints. Macrophages act as key drivers for the progression of RA, contributing to the perpetuation of chronic inflammation and dysregulation of pro-inflammatory cytokines such as interleukin 1 (IL-1). The goal of this study was to develop a macrophage-based cell therapy for biologic drug delivery in an autoregulated manner.

METHODS: For proof-of-concept, we developed "smart" macrophages to mitigate the effects of IL-1 by delivering its inhibitor, IL-1 receptor antagonist (IL-1Ra). Bone marrow-derived macrophages were lentivirally transduced with a synthetic gene circuit …

Failure In A Population: Tauopathy Disrupts Homeostatic Set-Points In Emergent Dynamics Despite Stability In The Constituent Neurons, James N Mcgregor, Clayton A Farris, Sahara Ensley, Aidan Schneider, Leandro J Fosque, Chao Wang, Elizabeth I Tilden, Yuqi Liu, Jianhong Tu, Halla Elmore, Keenan D Ronayne, Ralf Wessel, Kiran Bhaskaran-Nair, David M Holtzman, Keith B Hengen, Et Al.

2020-Current year OA Pubs

Homeostatic regulation of neuronal activity is essential for robust computation; set-points, such as firing rate, are actively stabilized to compensate for perturbations. The disruption of brain function central to neurodegenerative disease likely arises from impairments of computationally essential set-points. Here, we systematically investigated the effects of tau-mediated neurodegeneration on all known set-points in neuronal activity. We continuously tracked hippocampal neuronal activity across the lifetime of a mouse model of tauopathy. We were unable to detect effects of disease in measures of single-neuron firing activity. By contrast, as tauopathy progressed, there was disruption of network-level neuronal activity, quantified by measuring neuronal …

Volumetric Body Composition Analysis Of The Cancer Genome Atlas Reveals Novel Body Composition Traits And Molecular Markers Associated With Renal Carcinoma Outcomes, Olesya Mironchuk, Andrew L Chang, Farzaneh Rahmani, Kaitlyn Portell, Elena Nunez, Zack Nigogosyan, Da Ma, Karteek Popuri, Vincent Tze Yang Chow, Mirza Faisal Beg, Jingqin Luo, Joseph E Ippolito

2020-Current year OA Pubs

Clinically, the body mass index remains the most frequently used metric of overall obesity, although it is flawed by its inability to account for different adipose (i.e., visceral, subcutaneous, and inter/intramuscular) compartments, as well as muscle mass. Numerous prior studies have demonstrated linkages between specific adipose or muscle compartments to outcomes of multiple diseases. Although there are no universally accepted standards for body composition measurement, many studies use a single slice at the L3 vertebral level. In this study, we use computed tomography (CT) studies from patients in The Cancer Genome Atlas (TCGA) to compare current L3-based techniques with volumetric …

Induction Of A Distinct Macrophage Population And Protection From Lung Injury And Fibrosis By Notch2 Blockade, Mayra Cruz Tleugabulova, Meizi Liu, Michael S Diamond, Et Al.

2020-Current year OA Pubs

Macrophages are pleiotropic and diverse cells that populate all tissues of the body. Besides tissue-specific resident macrophages such as alveolar macrophages, Kupffer cells, and microglia, multiple organs harbor at least two subtypes of other resident macrophages at steady state. During certain circumstances, like tissue insult, additional subtypes of macrophages are recruited to the tissue from the monocyte pool. Previously, a recruited macrophage population marked by expression of Spp1, Cd9, Gpnmb, Fabp5, and Trem2, has been described in several models of organ injury and cancer, and has been linked to fibrosis in mice and humans. Here, we show that Notch2 blockade, …

Crispr/Cas9 Screens Identify Key Host Factors That Enhance Rotavirus Reverse Genetics Efficacy And Vaccine Production, Yinxing Zhu, Meagan E Sullender, Danielle E Campbell, Leran Wang, Sanghyun Lee, Takahiro Kawagishi, Gaopeng Hou, Alen Dizdarevic, Philippe H Jais, Megan T Baldridge, Siyuan Ding

2020-Current year OA Pubs

Rotaviruses pose a significant threat to young children. To identify novel pro- and anti-rotavirus host factors, we performed genome-wide CRISPR/Cas9 screens using rhesus rotavirus and African green monkey cells. Genetic deletion of either SERPINB1 or TMEM236, the top two antiviral factors, in MA104 cells increased virus titers in a rotavirus strain independent manner. Using this information, we optimized the existing rotavirus reverse genetics systems by combining SERPINB1 knockout MA104 cells with a C3P3-G3 helper plasmid. We improved the recovery efficiency and rescued several low-titer rotavirus reporter and mutant strains that prove difficult to rescue otherwise. Furthermore, we demonstrate that TMEM236 …

Perceived Stress Modulates Blood Pressure Reactivity To Stress In College Students, Manuel Sune, Natalie Younan, Caio Sousa

International Journal of Exercise Science: Conference Proceedings

Stress is an unavoidable part of everyday life that can have numerous effects on our bodies. In addition, the individual psychological perception of stress could represent a higher stress or stress reactivity in the physiological level, becoming the onset of many stress-related diseases. Persistently high levels of stress are common in college students and it's important to manage these levels to prevent the risk of health problems in the future. PURPOSE: The purpose of this study is to investigate the effect of perceived stress on cardiovascular reactivity to stress in college students. METHODS: Fourteen college students (f=5) participated in the …

The Effects Of Physical Activity On Cardiovascular Reactivity To Stress In College Students, Natalie Younan, Manuel Sune, Caio V. Sousa

International Journal of Exercise Science: Conference Proceedings

Stress is part of everyday life. Chronic stress can be a contributor to many physiological and psychological health problems. Chronic stress is also related to hyperreactivity to acute stress. PURPOSE: In this study, we aimed to investigate whether students with low, moderate, and high levels of physical activity (PA) have distinct cardiovascular responses to the cold pressor test (CPT). METHODS: College students (n=14; f=5) were given the short version of the International Physical Activity Questionnaire (IPAQ) to assess their physical activity levels. After the assessment, participants were set up to the FINAPRES with an arm cuff and finger …

Sled-Pull Training Decreases Rate Of Force Development In Men And Women Soccer Players, James Ma, John A. Brasher, Robert Musci, Jenevieve L. Roper

International Journal of Exercise Science: Conference Proceedings

Sled-pull training is a popular training method thought to increase lower extremity strength and power in athletes. Lower extremity strength and power are factors for success in sport, particularly soccer. Asymmetry is thought to negatively impact athletes, by increasing their risk of injury, and should be the focus of any training program. PURPOSE: To determine the impact of a 12-week sled pull training intervention on isometric leg rate of force development (RFD) and RFD asymmetry. METHODS: Thirty men (n = 15; 20 ± 1.5yrs, 168.28 ± 5.17cm, 73.44 ± 3.46kg) and women (n = 15; 19.58 ± 1yr, …

Heart Rate And Energy Expenditure Validity Of Garmin Instinct Devices During Hiking Outdoors With And Without Trekking Poles: A Pilot Study, Kavon Mcarthur, Bethany Hoag, Josie Gines, Myranda Peck, James Navalta, Facsm, Kelly Goonan, Julie E. Taylor, Marcus M. Lawrence

International Journal of Exercise Science: Conference Proceedings

ACSM has again named wearable technology the top fitness trend for 2024. Yet, the validity of wrist-worn devices for measuring average/maximal heart rate (HR) and estimating energy expenditure (EE) during outdoor hiking with and without trekking poles is unknown. PURPOSE: To determine the concurrent validity of identical Garmin Instinct devices to record valid measures of average and maximal HR as well as estimated EE during outdoor hiking with no poles, 1 or 2 trekking poles. METHODS: 11 (n=6 males, n=5 females, aged 20-39 yrs) adults randomly completed 3 pole conditions (no poles, 1 or 2 poles) during an ~10 min. …

Impact Of Running A 162-Km Mountain Race On Hydration And Gastrointestinal Response, Ryan Ott, Kamiry Robison, Kiara Fradin, Melani Kelly, Andrew Creer

International Journal of Exercise Science: Conference Proceedings

Gastrointestinal (GI) distress is a common complaint among runners, often worsening when less hydrated. PURPOSE: The purpose of this study is to evaluate hydration status and GI responses of 162-km ultramarathon runners. METHODS: 14 runners (11 males, 3 females; 36.9 ± 6.1 yrs, 72.5 ± 11.9 kg) completed the Bear 100 (7200m of vertical gain). Pre-, post-, and 24-h post-race completion, a survey to assess GI symptom presence was completed and weight and a urine sample was collected. Scored on a 10-point scale (0 = no problems; 10 = worst it has ever been), GI symptoms were divided into 1) …

The Effect Of Low Water Intake On Blood Glucose Measured With A Continuous Glucose Monitor, Doris Cheung, Safiya Rufino, Adam Seal

International Journal of Exercise Science: Conference Proceedings

The number of people with Type II diabetes is rapidly increasing worldwide. Previous studies have shown several factors contribute to the development of Type II diabetes, such as genetics, diet, and physical activity. Previous laboratory studies have demonstrated adequate water intake may slightly reduce post-prandial blood glucose. However, none have focused on the relationship between water intake and blood glucose excursions in a free-living situation. PURPOSE: This study aimed to examine the effect of low water intake on glucose regulation in a free-living situation using continuous glucose monitoring. METHODS: In a counterbalanced cross-over fashion, three participants were randomly …

Comparison Of Pulmonary Measures During Virtual Reality Exercise And Outdoor Exercise, Setareh Zarei, Devin Green, Myranda Peck, Olivia R. Perez, Eric Lambert, Ty Erickson, Lijie Zhou, James W. Navalta, Jeffrey Cowley

International Journal of Exercise Science: Conference Proceedings

The development of high-tech wearable devices is revolutionizing not only the way we live but also the way we exercise. Pulmonary responses to virtual reality (VR), as one of the latest technologies on the market, have been largely unstudied. To ensure that the workload is equivalent, one approach is to compare VR and outdoor (OUT) walks of similar visual environments. The findings from this study may be an initial step in providing evidence of VR as a platform for virtual exercise. PURPOSE: The purpose of this study was to assess whether walking in VR affects pulmonary responses differently than …

Effect Of Blood Flow Restriction Exercise On Post-Activation Potentiation In Resistance Trained Men And Women, Bulent Sokmen, Christopher Daniels, Melissa Aragon Matias, Garrett Campedel, Jairo Carrillo, Carter Michnevich, Cinthya Romano, Kandace Syer, Pauline Josephine Woodard, Hasan Ghadiri, Ibai Guadron, Arturo Ortiz, Collins Onyeukwu, Valentin Sanchez, Kent Abe, Monica Ohkubo

International Journal of Exercise Science: Conference Proceedings

Post-activation potentiation (PAP) is commonly employed to enhance the force-generating capacity of skeletal muscles. However, no studies have directly compared the PAP response elicited by blood flow restriction (BFR) exercise versus traditional bilateral training (TT). This distinction is critical, as differences in muscle activation are observed when comparing various exercise modalities. PURPOSE: Therefore, the purpose of this study was to investigate whether a BFR squat exercise would elicit a different PAP response compared to a traditional bilateral squat exercise. METHODS: A within-subjects repeated measures design was used to assess the acute effects of two distinct PAP protocols (traditional …

Effects Of Compression Sleeves On Muscle Oxygen Saturation During Graded Exercise In Acute Hypoxia, Geoffrey Dorsett, Nathan Chang, Hunter Paris, Jong-Kyung Kim, Trevor Gillum

International Journal of Exercise Science: Conference Proceedings

Lower partial pressure at altitude reduces the amount of oxygen able to be delivered to exercising muscles. Interventions to restore muscle oxygen saturation during hypoxic exercise have the potential to improve related measures like cardiac output and VO2. PURPOSE: The purpose of our study was to explore the effects of lower leg compression sleeves on muscle oxygen saturation during graded exercise in acute, normobaric hypoxia. METHODS: Seven male participants were recruited (Age = 24.5±3.2; Bodyfat% = 21.8±2.7; VO2 = 42.2±7.1) and underwent two graded exercise bouts at 20%, 40% and 60% of sea level VO2max in normobaric hypoxia (13.5% FiO2). …

Concurrent Heart Rate And Energy Expenditure Validity Of Polar Verity Sense Devices During Light And Moderate Intensity Resistance Training In Recreationally Active Adults: A Pilot Study, Collin Dawson, Spencer Maxwell, Olivia Perez, Setareh (Star) Zarei, Devin Green, Bethany Hoag, Michael Wong, Dustin Davis, Jeffrey C. Cowley, Merrill Funk, James W. Navalta Facsm, Marcus M. Lawrence

International Journal of Exercise Science: Conference Proceedings

Wearable technology is again the top fitness trend from ACSM for 2024. Our lab recently found that bicep-worn devices (Polar Verity Sense) are valid for measuring average/maximal heart rate (HR) but are not valid for estimating energy expenditure (EE) during acute resistance exercise training (RT). We postulated that the errors may have been due to the device’s algorithms assuming higher intensity during RT, but no study has directly tested these outcomes with various RT intensities. PURPOSE: To determine the concurrent validity of identical Polar Verity Sense bicep-devices to record valid measures of average and maximal HR as well as estimated …

Correlation Between Body Weight And Eccentric Hamstring Strength In American Football Players, Ty K. Hacking, Malorie Wilwand, Aaron W. Johnson, B. Brett Mortensen

International Journal of Exercise Science: Conference Proceedings

Hamstring strength and explosiveness is imperative for collegiate American football players to perform at the highest level. Understanding the respective correlations, based on players positions, between eccentric hamstring strength (HS) and body weight (BW) among football players may help coaches and players to develop strength protocols required for specific positions. We hypothesize that increasing BW will result in increased eccentric HS. PURPOSE: This study aims to examine the relationship between football players BW and their max eccentric HS. METHODS: As a secondary analysis from the HAMIR study, 95 (age: 21.4 ± 2.00 yr; Ht: 187.7 ± 6.17 cm; …

The Effects Of Blood-Flow Restriction Training On Bone Health At The Hip, Victoria Batlle, Sophia Lissin, Jacob Laubach, Todd Shoepe

International Journal of Exercise Science: Conference Proceedings

Bloodflow restriction training (BFR) partially restricts arterial inflow and completely restricts venous outflow to the working muscle to promote chemical signals of fatigue and is hypothesized to realize musculoskeletal adaptation with lighter training loads and volume. PURPOSE: The purpose was to determine short-term training effects of BFR on bone health in college-aged students. METHODS: 19 males (20.2±1.5 years, 25.5±4.7 kg/m2) and 21 females (20.2±1.8years, 24.3±3.4 kg/m2) were placed into control group (CON) or BFR groups based on stratified randomization. Hip scans from dual-energy x-ray absorptiometry (DXA) were performed before and after 7 weeks of BFR training at 50% …

The Effect Of Miniband Placement Variations On Hip And Knee Kinetics During Sidestep Activities, Makana Woods, Kevin Valenzuela, Riann Palmieri-Smith

International Journal of Exercise Science: Conference Proceedings

Utilizing the sidestep exercise as a regimen in a strength training program, has shown to improve hip muscle strength. However, varying band placement along the length of the legs may influence muscle activation and joint mechanics thereby influencing the effectiveness of the exercise. PURPOSE: The purpose of this study was to investigate the effect of band placement on hip muscle activation and peak hip and knee abduction moments during the sidestep exercise. METHODS: Three subjects (1 female and 2 males; age: 23 +/- 1.15 years old; height: 1.72 +/- 0.12 m; mass: 76.57 +/- 12.15 kg) performed five …