Medicine and Health Sciences Commons^™

The California Collaborative Network To Promote Data Driven Care And Improve Outcomes In Early Psychosis (Epi-Cal) Project: Rationale, Background, Design And Methodology, Valerie L Tryon, Adam B Wilcox, Et Al.

2020-Current year OA Pubs

BACKGROUND: A prolonged first episode of psychosis (FEP) without adequate treatment is a predictor of poor clinical, functional, and health outcomes and significant economic burden. Team-based "coordinated specialty care" (CSC) for early psychosis (EP) has established effectiveness in promoting clinical and functional recovery. However, California's CSC program implementation has been unsystematic and could benefit from standardizing its processes and data collection infrastructure. To address this, we established a consortium of EP clinics across the state via a Learning Health Care Network (LHCN) framework to develop the Early Psychosis Intervention Network of California (EPI-CAL). EPI-CAL's LHCN developed a core battery of …

Their Stories, Our Testimony: A Narrative Inquiry Into The Remote Teaching Experiences Of Community College Clinical Nurse Educators During The Covid-19 Pandemic, Catherine E. Fenner

Doctor of Education Program Dissertations

This narrative inquiry explored the lived experiences of clinical nurse educators who taught at community colleges during the COVID-19 global pandemic, contributing to the growing body of literature about what nurses endured during the pandemic. The pandemic and the ensuing havoc it caused occurred when the profession faced significant staffing shortages. In the early months of 2020, when the virus was spreading rapidly, many states issued stay-at-home orders requiring nursing programs to pivot to remote learning platforms. Teaching hands-on skills, communication techniques, and time management strategies through virtual and remote pedagogy was a time of confusion for nurse educators, who …

Use Of Intraosseous Vascular Access In Adults: A Systematic Review, Courtney Krol, Philip Ordonez, Khavir Sharieff D.O.

HCA-NSU MD Research Day

Objective. This study evaluates the efficacy of intraosseous (IO) access in adults compared to peripheral intravenous (PIV) access and examines associated benefits and complications. Background. IO access is more commonly used in children than adults for PIV access. Despite its increasing use, its efficacy and safety in adults remains less extensively studied, particularly in comparison to traditional PIV methods. Methods. A literature search was conducted in July 2024 using PubMed, Web of Science, and Ovid MEDLINE, using keywords such as “intraosseous” and “adults.” The review included studies published from 2010 onwards, patients aged 18 and older, and written in English. …

Comparative Analysis Of External Load Metrics In Mma Sparring And Kickboxing Sessions, Lauren Stern, Corey Peacock, Peter Byers

HCA-NSU MD Research Day

Comparative Analysis of External Load Metrics in MMA Sparring and Kickboxing Sessions, Lauren Stern, OMS-II, College of Osteopathic Medicine Objective. This study was conducted to compare external load and intensity metrics during different MMA training modalities. Background. PlayerLoad (PL) and PlayerLoad per Minute (PL/Min) are increasingly researched metrics that have shown predictive capability on intensity of workout and athlete fatigue. Previous studies have utilized Catapult Sports technology to measure external workload in MMA athletes but comparative data between two different training sessions remains inadequate. Methods. With the use of the Catapult Vector S7 accelerometer, 18 professional MMA athletes (average age …

Identification Of Nitro-Containing Compounds As Potent Inhibitors Of Glioblastoma Stem Cells Via Stat3 Pathway Suppression, Matthew Pate, Roberto Martin, Emma Baker, Blake Hutchins, Marie J. Moreno Hollweg, Sabrin Safar, Kyuree Chang, Eduardo A. Veliz, Steven Vanni, Regina Graham

HCA-NSU MD Research Day

Identification of Nitro-Containing Compounds as Potent Inhibitors of Glioblastoma Stem Cells via STAT3 Pathway Suppression Matthew C. Pate1, Roberto Martin2, Emma Baker1, Blake Hutchins1, Maria Moreno Hollweg1, Sabrin Safar1, Kyuree Chang1, Eduardo A. Veliz PhD3, Steven Vanni DO 1,4, Regina M. Graham PhD1 1Nova Southeastern University Dr. Kiran C Patel College of Allopathic Medicine, Fort Lauderdale, FL, USA, 2Nova Southeastern University Dr. Kiran C Patel College of Osteopathic Medicine, Fort Lauderdale, FL, USA, 3Department of Chemistry, University of Miami, Coral Gables, FL, USA ,4HCA Florida University Hospital, Davie, FL, USA, Objective: To examine cytotoxic effects of a series of nitro-compounds …

Type 1 Diabetes And The Gut Microbiome: What We Know And What The Future Holds, Angela Chen, Jyotsna Chawla, Cyril Blavo

HCA-NSU MD Research Day

Type 1 Diabetes and the Gut Microbiome: What We Know and What the Future Holds Angela Chen, OMS-II, Dr. Kiran C. Patel College of Osteopathic Medicine Objective. This paper explores the current understanding of the relationship between type 1 diabetes (T1D) and the gut microbiome, focusing on how the gastrointestinal microbial communities may contribute to autoimmune responses associated with T1D. Background. While the exact etiology of T1D remains unclear, it is widely recognized that its development results from a complex interplay of genetic predisposition, environmental factors, and lifestyle choices. Recent research has highlighted the significant role of the gut microbiome …

Observing The Impacts Of Different Diets On Clinical Outcomes In Patients With Alzheimer's Disease: A Scoping Review, Erjola Toska, Alessandra Ottley, Quinn Jackson, Rachel Fricker, Alexa Carleo, Gabriella Cutrali, Olivia D’Alessio, Raquel Rossman, Samuel Kruchakov, Abraham Edelstein, Lubov Nathanson

HCA-NSU MD Research Day

Observing the Impacts of Different Diets on Clinical Outcomes in patients with Alzheimer's disease: A Scoping Review Authors: Quinn Jackson, OMS-III; Rachel Fricker,OMS-III; Erjola Toska, OMS-III; Alessandra Ottley,OMS-III; Alexa Carleo,OMS-III; Gabriella Cutrali, OMS-III; Olivia D’Alessio, OMS-III; Raquel Rossman, OMS-III; Samuel Kruchakov, OMS-III; Abraham Edelstein,OMS-III; Lubov Nathanson, Ph.D. Program: Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Florida Objectives: This study aimed to assess the literature published from 2013 to 2023 on the impact of diet on Alzheimer’s Disease (AD). Background: AD is primarily marked by β-amyloid plaques and neurofibrillary tangles, which impair neuronal synapses, leading to memory …

Ansa Cervicalis-To-Phrenic Nerve Transfer: Technical Note With Potential Application For Diaphragmatic Reanimation In Patients With High Cervical Spinal Cord Injury, Jonathan Melnick, Mohammadali M. Shoja, Gary B. Schwartz

HCA-NSU MD Research Day

Objective. This study was conducted to determine whether utilization of the superior root of ansa cervicalis (SRAC) as the donor for phrenic nerve (PN) transfer is technically feasible. Background. In patients with high cervical spinal cord injury resulting in diaphragmatic paralysis, another donor, the spinal accessory nerve, has been used successfully to reinnervate the PN and restore diaphragmatic function. Methods. Eight neck sides underwent cadaveric surgery. The sternocleidomastoid muscle was retracted posteriorly, the SRAC and PN were isolated, and the SRAC was cut near its distal end and transposed to the ipsilateral PN as it crossed the anterior scalene muscle. …

An Epidemiological Approach To The Rise In Syphilis In The United States Between 2018 And 2022, Ashley Forrest, Erica Rankin, Lahana Maharjan, Cyril Blavo, Jyotsna Chawla

HCA-NSU MD Research Day

Objective. This study aimed to investigate the recent increase in syphilis rates from 2018 to 2022, utilizing publicly available data from the Centers for Disease Control and Prevention (CDC). Background. Syphilis has seen a dramatic resurgence since 2018, reaching levels not observed since the 1940s. While this increase has prompted significant discourse among healthcare professionals, a comprehensive demographic analysis remains limited. Methods. CDC public datasets from 2018 to 2022 were analyzed descriptively, followed by chi-squared tests and logistic regression modeling conducted using R. The analysis examined syphilis rates across different demographic and behavioral factors, including sex, race/ethnicity, and reported sexual …

Impact Of Rapid Eye Movement Sleep Disturbances In The Pathogenesis Of Alzheimer's Disease: A Scoping Review, Daniel Malak, Paul Mikhail, Joseph Mikhail, Joseph Swaress, Khavir Sharieff

HCA-NSU MD Research Day

Background: Rapid eye movement (REM) sleep disturbances have been implicated in accelerating cognitive decline in aging individuals and those with Alzheimer’s disease (AD). This review explores the relationship between REM sleep disruptions and the progression of AD. Methods: A comprehensive literature review was conducted in June 2024 across PubMed, Embase, Scopus, and Google Scholar using terms, “Alzheimer’s,” “REM,” and “sleep disturbances.” Articles focused on REM sleep disturbances in AD patients, excluding those with underlying sleep disorders, comorbidities, or genetic predispositions, were selected. Key data on tau pathology, beta-amyloid accumulation, cognitive decline, and neuroimaging findings were independently extracted and analyzed by …

Evaluating The Therapeutic Potential Of Tirzepatide In Liver Diseases: A Comprehensive Review, Carina Bryan, Zaneh Kahook, Talaya Jones, Mayur S. Parmar

HCA-NSU MD Research Day

Objective: This review examines tirzepatide, a GLP-1 agonist, to treat liver diseases like nonalcoholic fatty liver disease (NAFLD) and metabolic-associated steatohepatitis (MASH). Background: Initially FDA-approved for type 2 diabetes and obesity, tirzepatide shows potential benefits for liver diseases. Clinical studies are evaluating its hepatoprotective properties in NAFLD and MASH. Methods: The review includes primary studies and ongoing clinical trials from the last five years involving patients over 18 diagnosed with NAFLD or MASH. Search terms included tirzepatide, GLP1s, MASH, NAFLD, fibrosis, and albumin. Results: A clinical study demonstrated that after 52 weeks of tirzepatide treatment, MASH resolution without worsening fibrosis …

The Use Of Sodium-Glucose Transport Protein 2 Inhibitors In The Treatment Of Lupus Nephritis: A Preliminary Systematic Review, Stephanie Nagy, Marc M. Kesselman

HCA-NSU MD Research Day

Objective: To analyze the nephroprotective effects of SGLT-2 inhibitors, traditionally an antidiabetic medication, on the progression and outcomes of lupus nephritis (LN). Background: Systemic lupus erythematosus is a prevalent autoimmune condition resulting from the loss of tolerance against self-antigens. Widespread inflammation affects all body systems, especially the kidneys, resulting in lupus nephritis within 3 years. Lupus nephritis is a type 3 hypersensitivity that occurs due to immune complex deposition leading to inflammation of the nephrons that can progress to end-stage renal disease and renal failure if not treated effectively. Methods: A search was conducted using OVID, CINHAL, Web of Science, …

Gulf War Illness: Risk Of Cognitive Decline And Dementia, Nidhi Patel, Fabian Mantilla, Mayur Parmar Phd

HCA-NSU MD Research Day

Gulf War Illness: Risk of Cognitive Decline and Dementia 1Nidhi Patel, 1Fabian Mantilla, 2Mayur S. Parmar, PhD 1Class of 2026, Dr. Kiran C. Patel College of Osteopathic Medicine 2Assistant Professor, Pharmacology. Dr. Kiran C. Patel College of Osteopathic Medicine Objective. This review highlights the current understanding of neurological dysfunction associated with Gulf War Illness (GWI), specifically focusing on cognitive impairment and dementia as key complications. Background. GWI is a chronic multi-system disorder affecting a significant portion of veterans who served in the 1990-1991 Gulf War. Methods. This review synthesizes evidence from human and preclinical primary peer-reviewed studies evaluating the cognitive …

Coronary Artery Calcification In Rheumatoid Arthritis Patients, Stephanie Nagy, Jordan J. Ditchek, Marc M. Kesselman

HCA-NSU MD Research Day

Objective: To assess the need of coronary artery calcium scoring (CACS) in the standardized management of patients with rheumatoid arthritis (RA) for early identification, prevention of coronary artery obstruction and complications. Background: Worldwide, RA is a leading inflammatory arthropathy. The musculoskeletal impacts of RA are well known; however, the inflammatory nature of the disease extends beyond the joint synovium. The cardiovascular system is the most impacted and the leading cause of death. Recently, CACS has become a popular method to analyze the calcifications within the coronary vessels. Methods: A review was performed using CINHAL, OVID, EMBASE, and Web of Science. …

An Open Approach To Clinical Study Recruitment Automation, Andrew Bouras, Andrew Bouras, Dhruv Patel, Rahul Kataria

HCA-NSU MD Research Day

Objective: To present an innovative Patient Recruitment Automation System that leverages open standards and promotes open data in clinical research. Background: Patient recruitment for clinical studies faces challenges in efficiency, data security, and regulatory compliance. These issues can delay research timelines and impact healthcare advancements. Methods: We developed a system that integrates with Electronic Health Record (EHR) systems to identify potential participants using predefined criteria. The platform employs Azure-based infrastructure with advanced data protection techniques, ensuring HIPAA compliance. It features an automated screening process using adaptive questionnaires and a communication module for participant engagement. Results: The system demonstrates improved efficiency …

Association Between Motor Tests And Antiretroviral Medication Adherence In Older Adults With Hiv, Priyanka Ramanathan, Romil Pitale, Curtis Ko, Pranav Uppalapati, Viraj Padhiar, Bobby Bajwa, Raymond Ownby

HCA-NSU MD Research Day

Objective: This study evaluated measures of motor performance as predictors of medication adherence in older adults with HIV infection. Background: Patient adherence to HIV treatment is crucial for optimal clinical outcomes. Factors such as the complexity of drug regimens and financial constraints make ideal adherence difficult. While strategies promoting adherence exist, there is a lack of research on screenings that predict adherence. Previous research suggests motor performance is correlated with adherence but has not been extensively studied in older individuals. The integration of motor assessments into screenings of medication adherence may help to improve outcomes. Methods: Data were drawn from …

Revolutionizing Mandibular Osteoblastoma Treatment: The Power Of Computer-Assisted Virtual Surgical Planning, Leon Liu, Jason E. Portnof, Mullar Zakher Dds, Sandra Khuu Dmd, Renee Reich Dds

HCA-NSU MD Research Day

Clinical Abstract Introduction. Osteoblastomas are benign primary bone tumors that rarely arise in the jawbones. Often displaying features that make them difficult to discern from other bone-forming lesions, osteoblastomas may be aggressive in nature, making their expeditious diagnosis and detection crucial to maximize functional and aesthetic outcomes. Although mandibular osteoblastomas are traditionally treated with surgical excision, this paper explores the effectiveness of a computer-assisted approach with use of CBCT scans, virtual planning, and fabrication of custom surgical guides as a means to effectively plan proper resection of the defect. Case Description. This case series presents the diagnostic methods and surgical …

Otitis Media Causes In Children And The Role Of Osteopathic Manipulative Techniques In Its Treatment, Laure Deliscar, Jyotsna Chawla, Cyril Blavo

HCA-NSU MD Research Day

Objective: This study was conducted to examine the disease process of pathogens in the middle ear space while considering the effectiveness of treatment methods. Background: Otitis Media (OM) is a common infection of the middle ear, presenting in acute, chronic, and effusion forms. It is characterized by erythematous inflammation of the middle ear space spanning from the tympanic membrane to the end of the eustachian tube, and is often accompanied by fever, earache, and often temporary hearing loss. While OM can affect all age groups, it disproportionately impacts children under the age of 6 and is a leading cause of …

A Systematic Review Of Economic Evaluations Of Clinical Pharmacy Services In The United States: 2018-2022, Abdullah Alsharif, Bertha De Los Santos, Micheal Kim, Daniel Touchette, Alexandra Perez

HCA-NSU MD Research Day

Title: A systematic review of economic evaluations of clinical pharmacy services in the United States: 2018-2022 Authors: Bertha De Los Santos PharmD MS, Michael Kim PharmD, Abdullah Alsharif PharmD, Daniel Touchette PharmD MA, Alexandra Perez PharmD MS Background: Our objective was to identify, evaluate and synthesize evidence on the economic impact of clinical pharmacy services (CPS) compared to usual or alternative care in the United States. Methods: We searched Ovid MEDLINE, PubMed, IPA, Embase, and CINAHL in September 2023 for US-based pharmacist-led clinical interventions published between January 2018 and December 2022. We excluded articles with a team-based intervention where the …

Real-World Safety And Efficacy Of Elranatamab In Patients With Relapsed Or Refractory Multiple Myeloma, Parker Melnick, Ariel Grajales-Cruz Md, Doris K. Hansen Md, Omar Castaneda Md, Allison Graeter Md, Mariola A. Vasquez-Martinez Md, Shrikar Modukuri Ms, Brandon Blue Md, Julia Fadul Pharmd, Ariel Denson Pharmd, Filip Ionescu Md, Shrin Thapa Md, Gabe De Avila, Kristy Harvey Pa-C, Blanca Lopez Pa-C, Katherine Tobon Pharmd, Hien Liu Md, Jose Ochoa-Bayona Md, Ciara L. Freeman Md, Frederick L. Locke Md, Taiga Nishihori Md, Kenneth H. Shain Md, Rachid Baz Md, Melissa Alsina Md

HCA-NSU MD Research Day

Objective. This study was conducted to assess the real-world safety and efficacy of elranatamab in patients with relapsed or refractory multiple myeloma (RRMM). Background. Multiple myeloma is a hematological malignancy marked by uncontrolled proliferation of clonal plasma cells. Elranatamab is a humanized B-cell maturation antigen (BCMA)-CD3 bispecific antibody. In August 2023, the FDA granted elranatamab accelerated approval for the treatment of patients with RRMM based on positive results from the Phase II MagnetisMM-3 clinical trial. However, the drug’s real-world safety and efficacy have yet to be established. Methods. This retrospective chart review conducted at Moffitt Cancer Center evaluated 34 patients …

Laying The Foundation For Successful Future Healthcare Students: The Importance Of Basic Science Education, Aymen Arain, Ricardo Rodriquez Millan, Adalyne Singh, Katlynn Kenon, Andrew Mariassy, Yuri Zagvazdin, Michelle Demory, Cheryl Purvis

HCA-NSU MD Research Day

KEYWORDS: basic sciences, histology, physiology, neuroanatomy, supplemental resources, graduate education, medical education Objective: To assess students’ needs and identify additional supplemental resources necessary to be successful in basic sciences courses. Background: As basic science faculty teaching pre-health majors, we recognize the struggles students face when dealing with challenging topics in anatomy and physiology. However, we often fail to recognize the importance of these foundational sciences in our students’ journey to becoming future healthcare professionals. Methods: In our study, we surveyed students in our Master of Biomedical Sciences (MBS) program interested in a variety of healthcare professions. Using a fourteen-question survey …

Insight Into Galeazzi Fracture With Ulnar Nerve Compression, Pedro Jimenez, Diana Ghisa, Ivan Kliuikov, Nicholas Riemen, Gary Schwartz, Mohammadali Shoja

HCA-NSU MD Research Day

Insight into Galeazzi Fracture with Ulnar Nerve Compression Pedro Jimenez, B.S.1, Diana N. Ghisa, B.S.1, Ivan Kliuikov, B.S.1, Nicholas Riemen, B.S.1, Gary Schwartz, M.D.2, Professor Mohammadali M. Shoja, M.D.2 1MS-II, Dr. Kiran C. Patel College of Allopathic Medicine 2Professor, Dr. Kiran C. Patel College of Allopathic Medicine Introduction. Galeazzi fractures are a well-documented orthopedic injury, involving a fracture of the distal third of the radius with a dislocation of the distal radioulnar joint (DRUJ). However, ulnar nerve compression associated with Galeazzi fractures is rare. This case report presents a 51-year-old female with a Galeazzi fracture following a motor vehicle accident, …

Bilateral Popliteal Entrapment Syndrome: A Rare And Challenging Case Report, Jose Burgos, Gabriela Llerena, Spencer Rheingold, Jorge De La Portilla

HCA-NSU MD Research Day

Bilateral Popliteal Entrapment Syndrome: A Rare and Challenging Case Report Burgos, Jose Julian, MD, MDIV, HCA Florida Kendall Department of Vascular Surgery Miami, Florida. Llerena, Gabriela2, OMSIV, Nova Southeastern University Dr. Kiran Patel College of Osteopathic Medicine. Rheingold, Spencer, MSIV, Nova Southeastern University Dr. Kiran Patel College of Allopathic Medicine. De La Portilla, Jorge MD, assistant professor, HCA Florida Kendall Department of Vascular Surgery Miami, Florida1 Objective: This case describes an atypical presentation of PES in an older male patient who presented with a sudden onset of symptoms without a history of claudication. Background: Popliteal entrapment syndrome (PES) is a …

Management Of Covid-19 In A Patient With Kartagener Syndrome: A Case Report, Yatin Ramesh Babu, Shivani Patel, Andy Aleman Espino, Mallory Kazaleh, Hamlet Monteagudo, Odalys Frontela

HCA-NSU MD Research Day

The unprecedented global health challenge posed by COVID-19, caused by SARS-CoV-2, has driven research into its diverse clinical manifestations and underlying pathophysiological mechanisms. This report explores the interplay between pre-existing conditions, particularly Kartagener Syndrome, and COVID-19 outcomes. Kartagener Syndrome, characterized by primary ciliary dyskinesia, presents a unique perspective due to its anatomical and physiological features. The case details a 63-year-old female with Kartagener Syndrome admitted with COVID-19 symptoms. The gold-standard approach for Kartagener Syndrome involves comprehensive management strategies, including airway clearance techniques, pharmacotherapy, and surgical interventions. The patient's treatment encompassed bronchodilators, antibiotics, and subsequent improvements, leading to discharge with a …

Integrating Bioethics: Enhancing The Moral Compass Of Future Healthcare Professionals, Aymen Arain, Adalyne Singh, Ricardo Rodriquez Millan, Michelle L Demory, Cheryl Purvis

HCA-NSU MD Research Day

KEYWORDS: Bioethics, ethical principles, autonomy, justice, beneficence and non-maleficence, medical education Objective: To create an understanding of theoretical and practical ethical awareness in clinical practices and interprofessional healthcare teams. Background: The need for ethical competencies in our pre-health majors has never been more critical and the intersection of ethical thinking and real-world dilemmas are often disconnected. Enhancing self-awareness of ethical principles helps foster empathy and resilience, which are critical for building compassionate patient relationships. Methods: In our study, we surveyed students in our Master of Biomedical Sciences (MBS) program interested in a variety of healthcare professions (N=55). Using a ten-question …

Evaluating Tirzepatide's Therapeutic Potential In Mitigating Obesity-Associated Comorbidities, Zaneh Kahook, Talaya Jones, Carina Bryan, Mayur Parmar

HCA-NSU MD Research Day

Objective: The study aims to explore the therapeutic potential of dual GIP/GLP-1 agonist tirzepatide in managing obesity and its associated manifestations, including obstructive sleep apnea (OSA), hidradenitis suppurativa (HS), and obesity-associated cancer (OAC) risks. Background: OSA and HS are the associated comorbidities noted in persons with obesity. Obesity has been associated with an increased risk of cancers, such as breast cancer. Reducing obesity could improve these conditions. Tirzepatide has demonstrated efficacy in reducing body weight, but its benefits in obesity-related conditions and cancer risk need further investigation. Methods: Data was synthesized from peer-reviewed literature on tirzepatide. Additional sources were identified …

To Be Or Not Tb, Gerald Chang, Leidy Huie Martinez Md, Carlos Correa Md, Jose Melendez Md, Brittany Puebla Ms, Yeissen Godinez Md

HCA-NSU MD Research Day

Introduction: Tuberculosis (TB) is an aerosol-transmitted disease that primarily affects the lungs, with active infection presenting as fever, night sweats, weight loss, and productive cough. While it is prevalent worldwide, there may be a lower degree of clinical suspicion in developed countries where it remains uncommon. Therefore, it is important to focus on certain risk factors (travel history, immunosuppression, certain living conditions) in the patient workup. The purpose of this case report is to discuss the presentation and management of a patient with active TB presenting atypically. Case Description: The 47yo male patient with a recent history of pneumonia presented …

Invasive Squamous Cell Carcinoma Arising After Digit Amputation: A Case Study, Thy Nguyen, Leon Liu, Yin Kan Hwee, Mohammadali Shoja, Gary Schwartz

HCA-NSU MD Research Day

INTRODUCTION Squamous cell carcinoma (SCC), a malignant skin tumor, is commonly associated with osteomyelitis. Although an unusual occurrence, it is speculated that the tumor can spread along the tendon sheaths of the hand. The risk of malignant transformation is considerably increased in patients with a history of amputation. This may necessitate additional screening, amputation, or surgical repair of the defect. CASE PRESENTATION We present a patient with a progressively enlarging mass in his left hand following a prior finger amputation, which was later diagnosed as invasive SCC with concurrent osteomyelitis. Initial surgery involved mass excision and ray amputation of the …

Feeling Rash?, Ana Angeli, Erica Pieper, Ana Angeli, Nisha Chachad, Fernando Frias-Grishko, Jose Gonzalez-Pantaleon

HCA-NSU MD Research Day

Feeling Rash?

Melanio Rodriguez, MD1, Erica Peiper, DO2, Ana Angeli3, Nisha Chachad3, Fernando Frias-Grishko1, MD, Jose Gonzalez-Pantaleon, MD1

1Internal Medicine, HCA Florida Kendall Hospital 2Anesthesiology, HCA Florida Kendall Hospital 3Class of 2026, Nova Southeastern University Dr. Kiran C. Patel College of Allopathic Medicine Introduction: Our objective is to discuss a diagnostic approach for a maculopapular rash in an adult male with no past medical history or recent history of infection. This was a case where a wide differential was key to the diagnosis of the patient, as IgA vasculitis is rare in the adult population. Case Presentation: A 36 year-old …

Sex-Specific Changes In Gene Expression In Response To Stress In Individuals With Gulf War Illness, Lily Tehrani, Joshua Frank, Melanie Perez, Oskar Zarnowski, Raquel Rossman, Abraham Edelstein, Sadhika Uppalapati, Ana Reuthebuck, Rajendra Pangeni, Lubov Nathanson

HCA-NSU MD Research Day

Objectives The main objectives of this research proposal are to evaluate sex differences in circulating immune cells gene expression in GWI patients in response to stress modeled by exercise challenge, and sex differences in onset and progression of GWI. Background The underlying mechanisms associated with the onset and progression of GWI, a condition characterized by symptoms such as easy fatigability, memory problems, muscle and joint pain, gastrointestinal issues, neurological problems, and hormonal imbalance remains unclear. Methods We evaluated differentially expressed genes (DEG) (fold change ≥ 1.5, FDR ≤ 0.1) by RNA-seq in circulating lymphocytes of 20 GWI female and male …