Medicine and Health Sciences Commons^™

A Rare Case Of Bilateral Supraspinatus Tendon Tears With Unilateral Musculotendinous Junction Involvement In An Elderly Patient, Kanyamas Poompreecha, Patsaree Pattanasuwanna, Ya-Chu Hsu

Rehabilitation Practice and Science

Rotator cuff (RC) tears are a common cause of shoulder pain in the elderly, though tears at the musculotendinous junction (MTJ) are uncommonly observed. We present a rare case of bilateral supraspinatus tendon tears in a 68-year-old male, with unilateral involvement of the MTJ. Symptoms developed three months after resuming resistance training following left acromioclavicular dislocation surgery. Ultrasound revealed a full-thickness insertional tear on the left and a partial MTJ tear on the right. Conservative treatment led to symptom resolution without surgery. This case highlights the diagnostic value of dynamic ultrasound for subtle rotator cuff and MTJ lesions in elderly …

Label Correlated Contrastive Learning For Medical Report Generation, Xinyao Liu, Junchang Xin, Bing Tian Dai, Qi Shen, Zhihong Huang, Zhiqiong Wang

Research Collection School Of Computing and Information Systems

Background and Objective: Automatic generation of medical reports reduces both the burden on radiologists and the possibility of errors due to the inexperience of radiologists. The model that utilizes attention mechanism and contrastive learning can generate medical reports by capturing both general and specific semantics. However, existing contrastive learning methods ignore the specificity of medical data, that is, a patient may suffer from multiple diseases at the same time. This means that the lack of fine-grained relationships for contrastive learning will lead to the problem of insufficient specificity. Methods: To address the above problem, a label correlated contrastive learning method …

The Internist's Post V.1 N.11, The University Of Texas Rio Grande Valley. School Of Medicine, Eunbee Cho, Osiris Fernandez, Hector D. Preciado, Sobia Memon, Diana Acosta Pozo, Corey Haines, Roque Mifuji Lira, Martha Solis, Cesar Gutierrez

School of Medicine Publications

No abstract provided.

Autonomic Dysfunction In Gastroesophageal Reflux Disease. The Neurogastro-Cardiac Axis: Friend Or Foe?, Sergio Sobrino-Cossio, Jorge Cossío-Aranda, Elymir S. Galvis-García, Gualberto Mateos-Pérez, Óscar Teramoto-Matsubara, Jesús A. González-Hermosillo, Juan C. Lopez Alvarenga, Mustafa Azizoglu, José M. Remes-Troche

School of Medicine Publications

Gastroesophageal reflux disease (GERD) is a complex and highly prevalent entity. Impaired gut-brain communication is associated with autonomic dysfunction. Modulation of the autonomic nervous system controls gastrointestinal functions. In GERD, a decrease in vagal tone (parasympathetic activity) and an increase in sympathetic activity with autonomic balance shifted towards the sympathetic system have been reported. Clinical questionnaires and non-invasive measurement of heart rate variability may be useful in patients with GERD to detect autonomic dysfunction. Restoration of parasympathetic system activity (mainly neuromodulation), with subsequent improvement of parasympathetic activity, will reduce the intensity of autonomic symptoms and GERD, improving quality of life. …

Integrated Multi-Omics Analyses Of Synaptosomes Revealed Synapse-Associated Novel Targets In Alzheimer’S Disease, Subodh Kumar, Enrique Ramos, Axel Hidalgo, Daniela Rodarte, Bhupender Sharma, Melissa M. Torres, Davin Devara, Shrikanth Gadad

School of Medicine Publications

Synapse dysfunction is an early event in Alzheimer’s disease (AD) caused by various factors, including amyloid beta, p-tau, inflammation, and aging. However, the precise molecular mechanism underlying synapse dysfunction in AD remains largely unknown. To understand this, we comprehensively analyzed the synaptosomes fraction in post-mortem brain samples from AD patients and cognitively normal individuals. We conducted high-throughput transcriptomic analyses to identify changes in microRNA (miRNA) and mRNA levels in synaptosomes extracted from the brains of unaffected individuals and those with AD. Additionally, we performed mass spectrometry analysis of synaptosomal proteins in the same sample group. These analyses revealed significant differences …

Therapeutic Potential Of Brassica Carinata Microgreens Extract In Alleviating Symptoms Of Type 2 Diabetes In Wistar Rats, Lilian Nakakaawa, Ifeoluwa D. Gbala, Joel L. Bargul, Xavier Cheseto, John M. Wesonga

All Peer-Reviewed Publications

Microgreens of Brassica plants have attracted increasing research interest in the management of the prevailing epidemic of Type 2 diabetes mellitus (T2DM) because of their high nutritional value. This study evaluated the antidiabetic effects of Brassica carinata Microgreens Ethanolic Extract (BMEE) in type-2 diabetic rats. For the normoglycemic assay, rats were divided into five groups and received a single oral dose of 100, 250, and 500 mg/kg of BMEE while the control groups received distilled water and Glibenclamide. Fasting blood glucose (FBG) levels were determined on a weekly basis for 28 days in diabetic rats after treatment with BMEE at …

Comparing Patency Of Pulmonary Stent Implantation And Balloon Angioplasty In Pulmonary Vein Stenosis: A Systematic Review And Meta-Analysis, Izza Batool, Muhammad K. Khan, Muhammad Zohaib, Ibrahim A. Khan, Syed A. A. Bukhari, Shreeja Shah, Khaled Harmouch, Hussam Al Hennawi, Bruce D. Klugherz

Abington Jefferson Health Papers

Pulmonary vein stenosis (PVS) is an insidious diagnosis associated with morbidity and mortality. Pharmacologic therapy may suffice initially, but advanced stages demand mechanical intervention. Pulmonary stent implantation (PSI) and pulmonary balloon angioplasty (PBA) are common strategies, both carrying restenosis risks. This meta‐analysis compares PSI and PBA to determine the superior revascularization strategy. We systematically searched databases until November 2023, identifying 11 studies with 780 patients. Studies, including those involving patients undergoing balloon angioplasty (BA) or stent angioplasty (SA) for PVS, were selected. Case reports, editorials, and cross‐sectional studies were omitted. Primary outcomes included restenosis requiring reintervention, 5‐year freedom from restenosis, …

Revascularization Strategies For Multivessel Disease In Acute Coronary Syndrome: Network Meta-Analysis, Khaled M. Harmouch, Mohammad Hamza, Nomesh Kumar, Zarghoona Wajid, Neel Patel, Masooma Naseem, Jawad Basit, Prakash Upreti, Manoj Kumar, Waqas Ullah, Yasar Sattar, Timir K. Paul, Emmanouil Brilakis, M. Chadi Alraies

Abington Jefferson Health Papers

BACKGROUND: The optimal revascularization strategy for patients with acute coronary syndrome (ACS) and multivessel disease (MVD) remains debated. This study compares the efficacy and safety of different revascularization strategies in these patients.

METHODS: We included 20 studies comparing staged, complete, and culprit-only (CO) revascularization strategies in patients with ACS and MVD. We divided the revascularization strategies into 3 distinct strategies: CO, complete index procedure (CIP), and complete staged procedure (CSP). We then compared CIP and CSP with CO. Outcomes studied are all-cause mortality, cardiac death, recurrent myocardial infarction (MI), need for revascularization, bleeding, contrast-induced nephropathy (CIN), stroke, bleeding, and stent …

Nuclear Intron Sequence Variation Of The Bulinus Globosus Complex (Mollusca: Planorbidae): Implications For Molecular Systematic Analyses, Chairat Tantrawatpan, Kotchaphon Vaisusuk, Chrysantus M. Tanga, Warayutt Pilap, Naruemon Bunchom, Ross H. Andrews, Tongjit Thanchomnang, Wanchai Maleewong, Weerachai Saijuntha

All Peer-Reviewed Publications

Urinary schistosomiasis is caused by the blood fluke Schistosoma haematobium, which is predominantly found in Africa. The freshwater snail Bulinus globosus is its main intermediate host. The species that make up the B. globosus group are genetically complex, and their taxonomic status remains controversial. Genetic variation, heterozygosity, and DNA recombination in B. globosus were examined using the mitochondrial cytochrome c oxidase subunit 1 (COI) and the intron 3 region of the arginine kinase gene (AkInt3). A total of 81 B. globosus snails were collected from three different localities in Kwale County, Kenya. Genomic diversity, heterozygosity, DNA recombination, and haplotype network …

Disparities In Maternal Healthcare: Examining The Impact Of Social Determinants Of Health On Provider Care Quality, Rishita Anumukonda

Honors Undergraduate Theses

Poor maternal health outcomes among racially and socioeconomically marginalized populations are a major public health concern in the United States. Effective clinician discussions during prenatal and postpartum care play an essential role in promoting maternal and infant well-being. However, the content of provider-patient discussions in maternal care and how it varies for patients exposed to different social determinants of health has not yet been well explored. This study aims to examine whether healthcare provider discussions about key maternal health topics, including preventative health tips, risk factors, and available resources, differ based on social factors such as income level and race. …

Social Justice In Higher Education: The Forgotten Needs Of Students With Visual Impairments In Bangladesh, Mohammed Mozadded Hossen, Roy K. Chen, Nahal Salimi, Jane L. Nichols

School of Rehabilitation Services & Counseling Faculty Publications

Students with disabilities face myriad barriers and hurdles to success in higher education settings. Institutions in developing nations often lack the necessary resources to provide accessible instruction, and the absence of clearly defined policies further impedes upholding the educational rights of such a special population. The purpose of this study was to examine how undergraduate students with visual impairments in Bangladesh felt about their experiences related to social justice and challenges in learning during the COVID-19 pandemic. A convenience sample of 133 students was recruited from two public universities. The authors developed two instruments, namely, the Social Justice Experiences in …

Educational Case: Disseminated Intravascular Coagulation In A Patient With Cancer, Kripa Ahuja, Richard M. Conran

Department of Biomedical and Translational Sciences Faculty Publications

The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see https://www.sciencedirect.com/journal/academic-pathology/about/pathology-competencies-for-medical-education-pcme.

Validation Of Nutrition Focus Physical Assessment Via Telehealth, Ann Flickinger Ms, Rd, Ldn, Melissa Faura Rd, Ldn, Shae Duka Mph

Clinical Nutrition Service

No abstract provided.

Synthesising Cross-Speaker Data For Low-Resource Pathological Speech Recognition With Peft, Kesego Mokgosi, Milad Dadgar, Cathy Ennis, Robert Ross

Conference papers

Dysarthric speech recognition is essential for enhancing communication and accessibility for individuals with speech impairments, yet its development is hindered by a scarcity of robust, speaker-specific datasets. This study explores low-resource dysarthric speech recognition through cross-speaker transfer using synthetic data and parameter-efficient fine-tuning (PEFT). We integrate SpeechT5 text-to-speech (TTS) synthesis with x-vector speaker embeddings to generate speaker-specific dysarthric speech, enabling model adaptation while preserving pathological speech characteristics such as prosodic irregularities. Experiments on the TORGO dataset show that mixed cross-synthetic data with LoRA fine-tuning achieves a WER of 0.17, representing a 71.7% improvement over the standard model (0.60 WER) without …

Self-Awareness And Self-Efficacy In The Novice Professional Phase Of Marriage And Family Therapists After Person Of The Therapist Training, A Comparative Survey, Rubio Betsabé

Dissertations

The study focuses on examining the influence of person-of-the-therapist or self-of-the-therapist training on therapists’ self-reports of self-awareness (as a conscious awareness of one’s internal states and interactions with others) and self-efficacy (perceived beliefs in personal capabilities to perform in ways that give control over events that affect their lives) at the novice professional stage of their career. The study will examine the experiences reported by mental health providers actively providing clinical care by utilizing a survey design focusing on person of the therapist connecting through alumni lists and online solicitation. This research adds to the current literature by using a …

What Works In Telehealth Play Therapy? An Appreciative Heuristic Inquiry, Veronica Ann Ball

Dissertations

With the onset of coronavirus disease 2019 (COVID-19) in the United States in March 2020 (World Health Organization, 2020), professional counselors providing traditional in-person play therapy found themselves in a quandary regarding the delivery of services during a global pandemic (Evans, 2022; Mitchell, 2020; Whaibeh et al., 2020). Online counseling proffered a means to prevent the disruption of services, respond to the need for emerging counseling services, and comply with social restrictions (Evans, 2022). Prior to the pandemic, telehealth play therapy was used sparingly (Haslam & Harris, 2011; Smith et al., 2021), and many child-serving mental health professionals lacked training …

What About The Children? An Exploration Of Family Counselors' Play Therapy Training And Preparedness To Integrate Children Into Family Counseling, Patricia J. Walker Monical

Dissertations

Children are an important part of families, yet family counselor education programs often do not incorporate training for including children in family counseling. At some point in their careers, family counselors and therapists will encounter clients who have children 3–12 years old. The problem is that since these professionals often receive little to no training in play therapy and thus do not typically include young children in family therapy, these younger family members are often overlooked. Research has confirmed that, due to a lack of sufficient training and supervision in play therapy, many family therapists report feeling unprepared to work …

Power Training Impact On Running Ability After Traumatic Brain Injury: A Case Study, Sandra M. Tremblay Pt, Ms, Cws, Mscs

Department of Medicine

No abstract provided.

Can The Ability To Infer Relevance Account For Dimensional Psychoticism? An Exploration Of A Representative Community Sample, Adam Schwarz, Frank D. Baughman, Evan Dauer, Ruby Koyllor Alarcon Gleeson, Jennifer Haywood, Bo Huei Huang, Karen H. Heslop, Barbara A. Mullan, Susan L. Rossell, Nicolas H. Hart, Darren Haywood

Research outputs 2022 to 2026

Purpose: Psychoticism is a common feature of psychological disorders. Deficits in perceptual inference have been associated with the development of psychotic symptoms. Traditional testing of perceptual inference has had low ecological validity, limiting the ability to infer functional relationships. The aims of this study were to investigate the relationship between the capacity to infer relevance in dynamic environments and dimensional psychoticism, as well as to investigate the association between inferring relevance and dimensional psychoticism. Method: Four hundred participants, representative of the general population of the USA, completed an online questionnaire consisting of the Brief Symptom Inventory, as well as demographic …

Facilitators, Barriers, And Strategies For Supporting Shared Decision-Making With People With Intellectual Disability: A West Australian Primary Healthcare Professional Perspective, Kathryn Teale, Abigail Lewis, Rachel Skoss

Research outputs 2022 to 2026

Background: Shared decision-making between patients and primary healthcare professionals positively impacts health outcomes. However, people with intellectual disability face additional barriers and require supported shared decision-making (SSDM) to participate. Little is known about how healthcare professionals use SSDM with this population. This paper explores the facilitators and barriers experienced, and strategies/resources employed by healthcare professionals working with people with intellectual disability. Method: Ten purposively sampled primary healthcare professionals participated in semi-structured interviews. This descriptive qualitative study used content analysis. Findings were compared with a proposed model of factors influencing triadic (the person with intellectual disability, their caregiver and the healthcare …

Quality Over Quantity: Doula Perspectives On Equity, Access, And Quality Of Care In Black Maternal Health Outcomes, Terry-Ann E. Lynch

West Chester University Graduate Theses, Dissertations, and Final Projects

Black maternal mortality in the United States is a public health crisis. There are a plethora of reasons as to why maternal and fetal deaths disproportionately impact Black women. From a public health perspective, health disparities are an area of concern in marginalized communities, with Black maternal mortality being a risk factor. “According to the Centers for Disease Control and Prevention (CDC), in 2021, the maternal mortality rate for non-Hispanic Black (subsequently, Black) women was 69.9 deaths per 100,000 live births, 2.6 times the rate for non-Hispanic White (subsequently, White) women (26.6)” Maternal Mortality Rates in the United States, 2021” …

Evaluating Exclusion Criteria For Exertional Testing For Mild Tbi In An Outpatient Hospital-Based Organization, Amy Kerstetter Staub Pt, Dpt, Sandra M. Tremblay Pt, Ms, Cws, Mscs

Department of Medicine

No abstract provided.

Seeing The Unexpected: A Unique Case Of Naion With Temporal Vision Loss As A Periprocedural Complication Of Cerebral Angiography, Tejasvi Paturu, Ajay Menon Md, Negar Moheb Md, Casey Judge Do

Department of Medicine

No abstract provided.

Treatment Refusal By Cancer Patients: A Qualitative Study Of Oncology Health Professionals’ Views And Experiences In Australia, Moira O’Connor, Ashleigh Pantaleo, Tracey Williams, Mary Theophilus, Jordan Joseph, Nicolas H. Hart, Darren Haywood

Research outputs 2022 to 2026

In some cases, against medical advice, a person with cancer decides not to undergo any conventional, evidence-based cancer treatments including chemotherapy, radiotherapy hormone therapy and others. Estimates for treatment refusal range from 2.6% to 14.55%. Refusing evidence-based conventional cancer treatments is linked to rapid deterioration, poor prognosis and a higher risk of premature death. This study aimed to explore oncology health professionals’ experiences and views on why patients refuse standard cancer treatments. We employed an in-depth qualitative research design, adopting a social constructionist framework. Fourteen health professionals in Western Australia (WA) with experience working in oncology were interviewed. Four themes …

Moderate-To-Late Preterm Infants Benefit From The Early Collaborative Intervention: Primary Outcomes Of An Rct, Ulrika Birberg Thornberg, Felix Sebastian Koch, Charlotte Sahlén Helmer, Jonna Tell, Ellinore Nyberg, Thomas Abrahamsson, Evalotte Mörelius

Research outputs 2022 to 2026

Aim: This study aimed to determine the longitudinal impact of the EArly Collaborative Intervention (EACI), a three-session early intervention designed to enhance parent-infant interaction, on the developmental outcomes of preterm infants born between 30 + 0 and 35 + 6 weeks of gestation. Methods: This randomised controlled blinded study recruited families in two neonatal intensive care units in Sweden. In this one-year follow-up, 87 infants (standard care = 37, standard care with EACI = 50) were included in the intention-to-treat analysis. The primary study outcomes were cognition, receptive and expressive communication, and fine and gross motor development measured with the …

How Strong Is Strong Enough? Assessing When Physical Performance Tests Cease To Be Predictive Of Sprint Performance In Trained Football Players, Shayne Vial, Mark Scanlan, Philipp Beranek, Daniel Kadlec, Oliver R. Barley, Jodie Cochrane Wilkie

Research outputs 2022 to 2026

Vial, S, Scanlan, M, Beranek, P, Kadlec, D, Barley, OR, and Cochrane Wilkie, J. How strong is strong enough? Assessing when physical performance tests cease to be predictive of sprint performance in trained football players. J Strength Cond Res XX(X): 000-000, 2025 - Quantifying underlying capacities of sprint performance are useful for monitoring training and guiding interventions. Traditional statistical techniques, such as correlation and regression analyses, have been widely used to model relationships between physical capacity and sprint performance. However, these methods often assume linearity, potentially oversimplifying complex, nonlinear interactions, and generalizing group-level data that may misrepresent individual trends. For …

Navigating Ethical Complexities In Health Education: Exploring Challenges In Teaching Food And Health, E. Oljans, M. Quennerstedt, D. Barker, A. Caldeborg, V. Varea

Research outputs 2022 to 2026

Teaching food and health may be challenging, especially in classrooms where young people from different cultures, ethnicities, and religions meet. This article explores teachers’ navigation of ethical complexities when teaching food and health in classrooms with immigrant students. Five didactical strategies were identified: (1) The educare strategy, (2) The tiptoeing strategy, (3) The collegial support strategy, (4) The intercultural strategy, and (5) The pluralistic strategy. These didactical strategies are embedded in various educational settings. Our results demonstrate that a further focus on ethical and intercultural competence should be carefully supported and implemented in teacher education and continual professional development programmes …

Emotions And Cognition, Krystal D. Becks

Theses and Dissertations

Background: Cognitive functioning is linked to emotional processes, with this relationship shaped by various biological (e.g., age, sex, diseases, and genetics), psychological (e.g., emotional well-being, coping strategies, mental health), and sociological (e.g., income and education) factors. Understanding these interactions is critical for advancing research on cognitive-emotional health across diverse populations. Purpose: To examine the relationship between positive and negative emotions and cognitive functioning among healthy adults. Methods: This was a cross-sectional analysis of data from the Aging Brain Cohort (ABC) study (n=434). The independent variables were subsets from the NIH toolbox emotional battery. The dependent variables were from the NIH …

Investigating The Role Of Rps3 In The Homologous Recombination Dna Repair Pathway, Jerome Robert Dorsey

Theses and Dissertations

Ribosomal proteins have been demonstrated to perform extra-ribosomal functions beyond protein synthesis, including roles in cell signaling, transcription regulation, apoptosis, and DNA repair. Ribosomal protein S3 (RPS3), in particular, has been implicated in DNA repair and apoptosis pathways, suggesting a critical role in maintaining genomic stability. However, the specific mechanisms involving RPS3 are still unknown, particularly in the context of double-stranded break (DSB) repair. DSBs are among the most severe types of DNA damage, often resulting in chromosomal instability or cell death if not properly repaired. Nonhomologous End Joining (NHEJ) and Homologous Recombination (HR) are the two primary DNA repair …

Determinants Of Short Interpregnancy Intervals In High-Income Countries: A Systematic Review, J. Dunne, D. Foo, J. Jancey, G. Pereira, B. Kefale, D. G. Belay, G. Dhamrait, A. T. Gebremedhin, K. B. Mruts, S. D. Nyadanu, A. Roy, G. A. Tessema

Research outputs 2022 to 2026

Short interpregnancy intervals (IPIs) of <6–18 months are associated with adverse maternal and child outcomes. This study aimed to identify the individual, relationship, community, and societal factors that influence short IPIs in high-income countries. A comprehensive search was undertaken in CINAHL Plus, Ovid/EMBASE, Ovid/MEDLINE, Ovid/PsycINFO, ProQuest, PubMed, Scopus, Web of Science, and Google Scholar for articles published in English from 1st January 1990 to 26th October 2023. Studies were included if they reported an effect estimate of at least one determinant of pregnancy spacing in a high-income country. The quality of the included studies was assessed using the Johanna Briggs Institute Critical Appraisal Tool and Cochrane Risk Assessment Tool. Multi-level factors at the individual, relationship, community, and societal level were systematically identified through the socio-ecological model. This study is registered with PROSPERO (CRD42020176311). Of 2005 unique articles, 220 were identified for full-text review, and 55 met the inclusion criteria representing a total of 27,103,055 women from 13 high-income countries. All the included studies were deemed to be of moderate to high quality. Most of the studies reported determinants of short IPI at the individual level, with non-use of contraception the most common reported factor. Peer influence was a factor at the relationship level, and access to health care and reproductive services were impactful at the community and societal levels, respectively. Future research and efforts should support the development and implementation of policies and practices that support optimum pregnancy spacing from a comprehensive socio-ecological position.