Medicine and Health Sciences Commons^™

Implementation Of A Virtual Nurse Residency Program For Public Health Nurses: A Pilot Study, Ashlie L. Pullen

Journal of the Georgia Public Health Association

Implementation of a Virtual Nurse Residency Program for Public Health Nurses: A Pilot Study

Background: Nursing retention is a growing concern for many healthcare organizations. One of the Georgia Department of Public Health’s goals is to improve the recruitment and retention rates of public health nurses in the state. In this cohort study of nurses with less than 18 months of experience in public health, pre and post-tests were conducted to measure stress, confidence, job satisfaction, and public health core competencies.

Methods: The participants took part in asynchronous and synchronous online content led by public health professionals. These two modules …

Sex Differences In The Disease Progression Of Ftd Vs Ad, Abigail Mitchell, Danielle Frances, Chase Metzger

Science University Research Symposium (SURS)

Abigail Mitchell, Danielle Frances, Chase Metzger

Sex Differences in the Disease Progression of FTD vs AD.

Abstract

Neurodegenerative diseases are on the rise in aging populations due to the upper tier of the population getting larger in that age group (Zheng & Chen, 2022). Knowing this, there is great benefit in more accurate and early diagnosis of conditions like frontotemporal dementia (FTD) and Alzheimer’s disease (AD). Particularly, it is important to understand which variables may contribute to differences in disease burden and progression of associated sequalae, with one of those variables being biological sex. The current study investigated sex differences …

Understanding The Dynamics Of The Structural States Of Cannabinoid Receptors And The Role Of Different Modulators, Anjela Manandhar, Mona H. Haron, Michael L. Klein, Khaled Elokely

Faculty and Student Publications

The cannabinoid receptors CB1R and CB2R are members of the G protein-coupled receptor (GPCR) family. These receptors have recently come to light as possible therapeutic targets for conditions affecting the central nervous system. However, because CB1R is known to have psychoactive side effects, its potential as a drug target is constrained. Therefore, targeting CB2R has become the primary focus of recent research. Using various molecular modeling studies, we analyzed the active, inactive, and intermediate states of both CBRs in this study. We conducted in-depth research on the binding properties of various groups of cannabinoid modulators, including agonists, antagonists, and inverse …

Retrospective Evaluation Of Depression Screening Process Among Older Adult Patients In Primary Care For Quality Improvement., Ashley Dru Larson

Doctor of Nursing Practice Papers

Background: Depression is not a normal process of aging; it is a diagnosable and treatable medical condition. The US Preventive Services Task Force (USPSTF) recommends that older adults be screened for depression annually.

Aim: The purpose of this evidence-based practice (EBP) project was to evaluate the depression screening process for older adults (age 65+) in a primary health care setting and provide recommendations to the primary health care clinic for improving it.

Methods: This EBP project involved collecting retrospective data from August to October 2022, including aggregate data (demographics), from all older adults who were seen in …

Who Leads The Emergency Department Debrief?, Allison D. Lane, Ethan Bryce, Marcy R. Milbrandt, Lisa R. Stoneking

Journal of Wellness

No abstract provided.

An Assessment Of The Sexual And Mental Health Needs Of Transition Age Foster Youth In New York City, Elizabeth Claessens

Health Advocacy Theses

Young adults age 18 to 21 who are transitioning out or “aging out” of foster care are an extremely vulnerable group who lack typical family support and preparation for independent adulthood. All transition age foster youth have been exposed to trauma and likely have had multiple adverse childhood experiences. This population is understood to have significant mental and sexual health risks. Foster care service agencies in New York City provide mental and sexual (reproductive) health care to foster youth as mandated by the state of New York. This needs assessment seeks to better understand whether those services meet the mental …

Ankyrin Dependent Mitochondrial Function And Bioenergetics In The Heart, Janani Subramaniam, Janani Subramaniam

Dissertations & Theses (Open Access)

ANK2 mutations in patients are associated with numerous arrhythmias, cardiomyopathies, and other heart defects. In the heart, AnkB, the protein encoded by ANK2, clusters relevant ion channels and cell adhesion molecules in several important domains; however, its role at Mitochondria Associated ER/SR Membranes (MAMs) has yet to be investigated. MAMs are crucial to mitochondrial function and metabolism and are signaling hubs implicated in various cardiac pathologies. Among several functions, these sites mediate the direct transfer of calcium from the ER/SR to the mitochondria to modulate ATP synthesis. Given that mitochondrial function and energy production are paramount to cardiovascular heath, …

Perceived Quality Of Senior Care In An Assisted Living Facility Following The Outbreak Of Covid-19, Kaylie Hill

Theses/Capstones/Creative Projects

The COVID-19 pandemic has posed a monumental obstacle to the healthcare field in terms of severely reducing the number of healthcare workers. Among the many industries affected by staffing shortages are assisted living facilities (ALFs), in which residents are dependent on care staff for daily assistance. This study sought to investigate whether long-term residents of ALFs perceive a difference in the quality of their care under the circumstances of the pandemic as opposed to those of pre-pandemic times. Semi-structured interviews were facilitated with 10 long-term residents who have been residing in an Omaha ALF since prior to the outbreak of …

An Analysis Of Equity In Service Provided By The Snap-Ed Program: A Comparison Of Dietary Outcomes Among African American And White Participants In Louisiana, Matthew Greene, Rhiannon Kroeger, Samuel Stroope, Bailey Houghtaling, Denise Holson

Journal of Human Sciences and Extension

Structural racism has contributed to increased poverty, food insecurity, and obesity rates among African Americans relative to Whites. Nutrition education programs should therefore consider how well they serve this population. The objective of this investigation was to assess whether African American and White Supplemental Nutrition Assistance Program Education (SNAP-Ed) participants in Louisiana had comparable dietary behavior outcomes by conducting secondary data analysis of previous program evaluations from 2017-2018 and 2018-2019 among African American and White SNAP-Ed participants (n = 434). Variables measured included pre- to post-intervention changes in dietary behaviors (e.g., self-reported consumption frequency of fruit, vegetables, whole grains, low-fat …

Early Versus Delayed Umbilical Cord Clamping During Cesarean Section Of Pregnant Women With Preeclampsia: Maternal And Neonatal Outcome, Ahmed Korkor, Mofeed Mohamed, Mohamed Abdelmoaty

Al-Azhar International Medical Journal

Background: umbilical cord serves like a conduit for fetus's gas exchange, nourishment, & endocrinal homeostasis. Clamping of umbilical cord marks watershed moment in development of foetus into independent entity. Aim of the work: To compare effects of early versus delayed cord clamping on intraoperative blood loss during caesarean delivery in cases with severe preeclampsia. As well as to compare neonatal benefit of delayed cord clamping versus early cord clamping. Patients and methods: This randomized prospective control study was conducted, including 60 near term pregnant women with severe preeclampsia candidate for termination by cesarean delivery and the surgery was performed by …

Role Of Rouviere's Sulcus In Identification And Dissection Of Calot's Triangle During Laparoscopic Cholecystectomy, Baha El-Dein El-Saman, Adel Abdulhalim Lasheen, Waleed Abdelaty

Al-Azhar International Medical Journal

Background - One of most common surgical technique applied overall the world is laparoscopic cholecystectomy due to the high features instead of another surgical techniques. Furthermore; it is represents as the main technique for gallstones treatment; however the incidence of bile-duct injury still higher than that of open cholecystectomy. Various surgical procedures and principles have been proposed to reduces bile duct injury. Aim - to determine the frequency and the type of Rouviere’s sulcus and its importance as landmark during laparoscopic cholecystectomy. Patients and Methods - This prospective study included hundred-patients who had symptomatic gallstone disease and underwent laparoscopic cholecystectomy …

Myocardial Infarction With Nonobstructive Coronary Arteries In New-Onset Inflammatory Bowel Disease, Benjamin B. Claxton, George Sun, Ritu Nahar, Christopher Henry

Division of Gastroenterology and Hepatology Faculty Papers

No abstract provided.

Comparing Shaping Ability Of Fanta, Onecurve, And Protaper Next Ni-Ti Rotary Files Systems., Soliman N. Mansour, Maram Obeid, Tariq Yehia

Mansoura Journal of Dentistry

Objective: To compare the shaping ability of Fanta, One Curve, and Pro Taper Next Ni-Ti rotary file systems. Materials and Methods: Sixty Mandibular molars with mesiobuccal canals with curvatures ranging between 20° and 40° were divided into three groups of 20 teeth each. a group for each system as follows: group 1 was prepared by Fanta file system, group 2 was prepared by Pro Taper Next file system, and group 3 was prepared by One Curve file system. The measuring of canal curvatures was determined by Schneider's method using standardized periapical radiographs and the Image J software. Pre and post-CBCT …

Comparative Study Of Protrusive Record Accuracy With And Without George Gauge For Dentulous Cases, Aisha Z. Mostafa, Noha H. El-Shaheed

Mansoura Journal of Dentistry

Objective: This study aimed to evaluate the accuracy of the George gauge in protrusive records. Materials and Methods: This clinical trial includes a total of 12 dentulous subjects aged 20 to 40 years with no signs of muscular disease or temporomandibular joint disorders were chosen. For each patient, two different protrusive records were created, one with and one without the George gauge, using polyvinyl siloxane materials. The accuracy of these two protrusive records was evaluated by measuring the amount of midline shift in both records with a digital calliper. Then these Protrusive records were used to programme the articulator and …

Soft Metal Versus Laser Melting Metal Framework Used For Mandibular All On Four Implant Supported Fixed Complete Denture, Noha H. Rashed, Noha H. El Shaheed, Wael M. Said Ahmed, Salah A. Hegazy

Mansoura Journal of Dentistry

Objective: To radiographically evaluate the peri-implant bone height changes eri-implantin mandibular all on-four implant supported fixed complete denture (ISFCD) regarding metal framework fabrication technique either with milling from soft metal block or additive manufacturing using laser melting. Materials and Methods: Ten completely edentulous patients were rehabilitated with mandibular all on-four ISFCD. Computer-guided surgical procedures were followed for placement of implants. Patients were allocated randomly into two groups according to the framework fabrication technique. Group I frameworks were milled from soft metal block and group II frameworks were fabricated with additive manufacturing using laser melting. Vertical bone height changes around supporting …

A Machine Learning Approach For Predicting Patient Mortality With Heart Rate Variability Statistics, Matthew Thiele, Dario Ghersi

Theses/Capstones/Creative Projects

The prediction of patient mortality in the healthcare system provides a metric by which hospitals can better manage patient care and assess the needs of each individual patient. As such, the development of better predictive methods is vital for improving patient outcomes and overall quality of care. Heart rate variability (HRV) is a measure of the heart’s complex beating patterns, giving medical professionals additional insight into patient health. Previous research has demonstrated the potential use of heart rate variability as a metric for patient mortality prediction for various conditions, however more work is necessary to validate HRV as a metric …

An Unexpected Case Of Non-Uremic Calciphylaxis In A Patient With Multiple Risk Factors, Shannon Nugent, Fred Karaisz, Maisa Elbadawi, Andrew Touati, Neda Nikbakht, Jason B. Lee, Hasan Arif

Division of Internal Medicine Faculty Papers & Presentations

A 58-year-old woman with a history of morbid obesity, asthma, and prior warfarin use presented to the hospital with shortness of breath and a three-month history of painful, ulcerated ulcers with retiform purpura of her bilateral distal extremities. A punch biopsy specimen demonstrated focal necrosis and hyalinization of the adipose tissue with subtle arteriolar calcium deposition, findings consistent with calciphylaxis. We discuss the presentation of non-uremic calciphylaxis and review the risk factors, pathophysiology, and interdisciplinary management approach of this rare disease.

Neonate, Infant, And Child Mortality In North Africa And Middle East By Cause: An Analysis For The Global Burden Of Disease Study 2019, Sadaf G. Sepanlou, Hossein Rezaei Aliabadi, Reza Malekzadeh, Ali. A. Asadi-Pooya

Global Health Articles

Background: During the past three decades, neonate, infant, and child mortality declined in North Africa and Middle East. However, there is substantial heterogeneity in mortality rates across countries.

Methods: This study is part of the Global Burden of Diseases study (GBD) 2019. We report the number as well as mortality rates for neonates, infants, and children by cause across 21 countries in the region since 1990.

Results: Between 1990 and 2019, the neonate mortality rate in the region declined from 31.9 (29.8, 34.0) to 12.2 (11.1, 13.3) per 1000 live births. Respective figures for under 5 mortality rates (U5MRs) were …

Addressing Mental Health Issues Through A Screening Tool, Simran Sandhu

Capstone Projects and Master's Theses

This capstone project was implemented at Rancho San Juan High School which is located on the far north side of Salinas, CA. RSJHS is a newly constructed public high school. The capstone project's goal was to assist RSJHS Wellness Center by determining what services are needed by removing obstacles to accessing services. Intervention services can benefit students greatly. Services focus on mental, emotional, and socioeconomic needs. The project was specifically focused on creating a screening tool for the intervention specialist. A standard screening tool form was developed. The form is a well-organized easy to understand form that contains some personal …

Clinical Advantages Of Immediate Posterior Implants With Custom Healing Abutments: Up To 8-Year Follow-Up Of 115 Cases, Richard Akin, Andrew G. Chapple

School of Dentistry Faculty Publications

Purpose: Proper management of the soft tissues around dental implants is crucial to their long-term function and esthetics. The purpose of this article is to report the survival rate of immediate posterior implants when using an immediate chair-side technique for custom healing abutments. Materials and Methods: The investigator implemented a retrospective case series analysis of a sample of 115 consecutive patients with 1 posterior dental implant placed between February 1, 2012 and December 9, 2014, in the author's private practice who underwent the previously published technique for immediate custom chair-side healing abutment fabrication. In this descriptive analysis, the primary outcome …

Perioperative Chanage In Cervical Lordosis And Health-Related Quality-Of-Life Outcomes, Jose A Canseco, Brian A Karamian, Parthik D Patel, Michael Markowitz, Joseph K Lee, Mark F Kurd, D Greg Anderson, Jeffrey A Rihn, Alan S Hilibrand, Christopher K Kepler, Alexander R Vaccaro, Gregory D Schroeder

Rothman Institute Faculty Papers

BACKGROUND: Surgeons have scrutinized spinal alignment and its impact on improving clinical outcomes following anterior cervical discectomy and fusion (ACDF). The primary analysis of this study examines the relationship between change in perioperative cervical lordosis (CL) and health-related quality-of-life (HRQOL) outcomes after ACDF. Secondary analysis evaluates the effects of fusion construct length on outcomes in patients grouped by preoperative cervical alignment.

METHODS: A retrospective cohort study was performed on an institutional database including patients who underwent 1- to 3-level ACDF. C2-C7 CL was measured preoperatively and at final follow-up. For primary analysis, patients were classified based on their perioperative cervical …

Heavy Metals As Risk Factors For Human Diseases - A Bayesian Network Approach, M Perrelli, R Wu, D J Liu, R G Lucchini, L Del Bosque-Plata, Michael Vergare, M P Akhter, J Ott, Claudia Gragnoli

Division of Endocrinology, Diabetes and Metabolic Diseases Faculty Papers

Modern industrial agricultural processes expose human beings to multifactorial environmental pollution including heightened levels of heavy metals. The effects of acute heavy metal exposures at toxic levels are usually known; they are tested for and treated promptly. The effects of low/moderate-level chronic heavy metal exposures are less known as they may be subclinical, and pathogenic effects may only manifest clinically over time under the disguise of a diagnosable disease or miscellaneous symptoms attributed to aging. Consequently, the health impact of low-moderate heavy metal exposure is unlikely to be identified. Furthermore, established heavy metal safety levels often fail to recognize the …

College Of Health Sciences Newsletter, College Of Health Sciences, Old Dominion University

College of Health Sciences Newsletters

December 2022 issue of Old Dominion University's College of Health Sciences Newsletter.

Clinical And Economic Evaluation Of A Proteomic Biomarker Preterm Birth Risk Predictor: Cost-Effectiveness Modeling Of Prenatal Interventions Applied To Predicted Higher-Risk Pregnancies Within A Large And Diverse Cohort, Julja Burchard, Glenn R Markenson, George R Saade, Louise C Laurent, Kent D Heyborne, Dean V Coonrod, Corina N Schoen, Jason K. Baxter, David M Haas, Sherri A Longo, Scott A Sullivan, Sarahn M Wheeler, Leonardo M Pereira, Kim A Boggess, Angela F Hawk, Amy H Crockett, Ryan Treacy, Angela C Fox, Ashoka D Polpitiya, Tracey C Fleischer, Thomas J Garite, J Jay Boniface, John A F Zupancic, Gregory C Critchfield, Paul E Kearney

Department of Obstetrics and Gynecology Faculty Papers

Objectives: Preterm birth occurs in more than 10% of U.S. births and is the leading cause of U.S. neonatal deaths, with estimated annual costs exceeding $25 billion USD. Using real-world data, we modeled the potential clinical and economic utility of a prematurity-reduction program comprising screening in a racially and ethnically diverse population with a validated proteomic biomarker risk predictor, followed by case management with or without pharmacological treatment.

Methods: The ACCORDANT microsimulation model used individual patient data from a prespecified, randomly selected sub-cohort (N = 847) of a multicenter, observational study of U.S. subjects receiving standard obstetric care with …

Vitamin D Enhances Type I Ifn Signaling In Covid-19 Patients, Shirin Hafezi, Fatemeh Saheb Sharif-Askari, Narjes Saheb Sharif-Askari, Hawra Ali Hussain Alsayed, Habiba Alsafar, Fatme Al Anouti, Qutayba Hamid, Rabih Halwani

All Works

The ability of Vitamin D (VitD) to modulate antiviral responses through induction of antimicrobial peptide is well established. However, the effect of VitD on host responses to SARS-CoV-2 is not well investigated. We here report the ability of VitD to enhance host IFN-alpha/beta (a/β) signaling both in vitro and among severe COVID-19 patients treated with VitD. Blood and saliva specimens were obtained from severe COVID-19 patients treated (43 patients), or not (37 patients), with vitD, during their stay in intensive care unit. Patients were followed up to 29 days following admission, and patient survival outcomes were collected. Higher activity levels …

Liver Injury After Sars-Cov-2 Vaccination: Features Of Immune-Mediated Hepatitis, Role Of Corticosteroid Therapy And Outcome, Cumali Efe, Anand V Kulkarni, Benedetta Terziroli Beretta-Piccoli, Bianca Magro, Albert Stättermayer, Mustafa Cengiz, Daniel Clayton-Chubb, Craig Lammert, Christine Bernsmeier, Özlem Gül, Fatima Higuera-De La Tijera, Margarita Anders, Ellina Lytvyak, Mete Akın, Tugrul Purnak, Rodrigo Liberal, Mirta Peralta, Berat Ebik, Serkan Duman, Nurhan Demir, Yasemin Balaban, Álvaro Urzua, Fernando Contreras, Maria Grazia Venturelli, Yılmaz Bilgiç, Adriana Medina, Marcos Girala, Fulya Günşar, Maria-Carlota Londoño, Theodoros Androutsakos, Ayelen Kisch, Alper Yurci, Fatih Güzelbulut, Yasir Furkan Çağın, Enver Avcı, Murat Akyıldız, Emine Kübra Dindar-Demiray, Murat Harputluoğlu, Rahul Kumar, Sanjaya K Satapathy, Manuel Mendizabal, Marcelo Silva, Stefano Fagiuoli, Stuart K Roberts, Neşe Karadağ Soylu, Ramazan Idilman, Eric M Yoshida, Aldo J Montano-Loza, George N Dalekos, Ezequiel Ridruejo, Thomas D Schiano, Staffan Wahlin

Faculty and Staff Publications

BACKGROUND AND AIMS: A few case reports of autoimmune hepatitis-like liver injury have been reported after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination. We evaluated clinical features, treatment response and outcomes of liver injury following SARS-CoV-2 vaccination in a large case series.

APPROACH AND RESULTS: We collected data from cases in 18 countries. The type of liver injury was assessed with the R-value. The study population was categorized according to features of immune-mediated hepatitis (positive autoantibodies and elevated immunoglobulin G levels) and corticosteroid therapy for the liver injury. We identified 87 patients (63%, female), median age 48 (range: 18-79) …

Synchronous Presentation Of Autoimmune Hepatitis And Multiple Myeloma, Binoy Yohannan, Allen C Omo-Ogboi, Varaha S Tammisetti, Adan Rios

Faculty and Staff Publications

Autoimmune hepatitis (AIH) is a rare immune-mediated disease predominantly seen in women and triggered by various environmental factors. Rarely, AIH can be triggered by an underlying malignancy. We report a woman in her 60s who presented with markedly abnormal liver biochemical tests. Serology was positive for anti-smooth muscle antibodies and a liver biopsy confirmed AIH. During the hospital course, she developed sepsis and acute renal failure requiring dialysis support. Serum protein electrophoresis (SPEP) showed a monoclonal IgG kappa protein of 1.92 g/dL and a bone marrow biopsy revealed 7% clonal plasma cells. She had lytic lesions on skeletal survey confirming …

A Pilot Survey: Retention In Pain Medicine Among Fellowship Trained Anesthesiologists, Sarang S Koushik, Kelly Leap, Kenneth Seier, Kay See Tan, Naum Shaparin, Alan D Kaye, Omar Viswanath, Grant H Chen

Faculty and Staff Publications

BACKGROUND: We aim to explore the factors related to job satisfaction among pain physicians and identify the reasons why individuals minimize or stop practicing outpatient pain medicine.

OBJECTIVES/STUDY DESIGN: This is a survey-based study with the primary goal to identify factors determining job satisfaction and dissatisfaction among pain medicine fellowship graduates who continue to practice and those who are no longer practicing interventional pain. A secondary goal is to elucidate reasons for anesthesiologists trained in pain medicine to leave pain medicine, despite an additional year of training, and to work as general anesthesiologists.

METHODS: In this study, all 114 pain …

Mind The Gaps: Assessing And Enhancing The Trustworthiness Of Mental Health Apps, Gary Kok Yew Chan

Research Collection Yong Pung How School Of Law

Mental health apps including artificial intelligence (“AI”)- powered apps and chatbots have raised serious concerns relating to safety, efficacy and privacy. This article assesses their trustworthiness based on lego-regulatory, ethical and technological measures in addressing the abovementioned concerns. Focusing on applications to mental health apps, it examines Singapore laws, regulations and guidelines relating to software-based and AI medical devices, data protection, consumer protection, advertising and medical negligence. Additionally, upon taking into account other non-binding ethical guidelines, certification standards and technological measures targeted at app developers, a few recommendations are offered for enhancing trust in mental health apps.

A Cluster-Randomized Controlled Trial Of Automated Internet Weight-Loss Programs In Primary Care: Role Of Automated Provider Feedback, Deborah F Tate, Jennifer L Kraschnewski, Caitlin Martinez, Molly Diamond, Susan Veldheer, Kevin O Hwang, Erik B Lehman, Chengwu Yang, Christopher N Sciamanna

Faculty and Staff Publications

OBJECTIVE: Despite the high prevalence of obesity and associated health risks in the United States adult population, few primary care providers (PCPs) have time and training to provide weight-management counseling to their patients. This study aims to compare the effect of referral to a comprehensive automated digital weight-loss program, with or without provider email feedback, with usual care on weight loss in patients with overweight or obesity.

METHODS: A total of 550 adults (mean [SD], 51.4 [11.2] years, BMI = 35.1 [5.5] kg/m

RESULTS: Weight changes (mean [SE]) at 12 months were -0.92 (0.46), -3.68 (0.46), and -3.58 (0.48) kg …