Medicine and Health Sciences Commons^™

Virtual Learning In Emergency Medicine Residency Programs, Ashley Rider, Laura Oh, Rahul Bhat, Michael Gottlieb, Bruce Lo, Ulemu Luhanga, Shayne Gue, Jason Laenngfeld, Sarah Greenberger, Jeffery Hill, Jonathan Heidt

Department of Emergency Medicine Faculty Publications

During the COVID-19 pandemic, educational systems worldwide faced significant disruptions as in-person learning became unfeasible. In response, many institutions, including graduate medical education programs, swiftly transitioned to virtual learning platforms to adapt to these challenges. The rapid and unplanned pivot in learning format resulted in temporary negative impacts on residency training. Conversely, the experience of the rapid shift may have resulted in some long-term benefits while also preparing programs for future disruptions. This review aimed to discuss the advantages and disadvantages of virtual learning, potential mitigation strategies for the realized disadvantages, and potential areas of future research.

The Impact Of Ultra-Processed Foods On Cardiovascular Diseases And Cancer: Epidemiological And Mechanistic Insights, Olorunfemi Oyewole Babalola, Ebenezer Akinnusi, Paul Olamide Ottu, Kpomah Bridget, Godspower Oyubu, Samuel Ayomikun Ajiboye, Sakariyau Adio Waheed, Amafili Chibuzo Collette, Hameedah Oluwatoyin Adebimpe, Chibuzo Valentine Nwokafor, Ebenezer Ayomide Oni, Precious Olayinka Aturamu, Opeyemi Iwaloye

Chemistry & Biochemistry Faculty Publications

Ultra-processed foods (UPFs) are increasingly recognized as contributors to the pathogenesis of cardiovascular diseases (CVDs) and cancer due to their adverse compositional and mechanistic effects. UPFs, distinguished by their high content of unhealthy fats, sodium, refined sugars, and synthetic additives, significantly increase dyslipidemia, hypertension, and obesity, which are key risk factors for CVDs. Chronic consumption leads to systemic inflammation, gut microbiota dysbiosis, endothelial dysfunction, and oxidative stress. Additives such as artificial sweeteners and sodium nitrites in UPFs are associated with carcinogenesis through mechanisms involving genotoxicity and promotion of inflammatory microenvironments. This review critically evaluates existing epidemiological, mechanistic, and clinical evidence …

Amorphous Quininium Aspirinate From Neat Mechanochemistry: Diffracting Nanocrystalline Domains And Quick Recrystallization Upon Exposure To Solvent Vapours, Silvina Pagola, James Howard, Johannes Merkelbach, Danny Stam

Chemistry & Biochemistry Faculty Publications

Quininium aspirinate is mechanochemically prepared as a crystalline solid by liquid-assisted grinding, or as an amorphous phase (as determined by X-ray powder diffraction), by neat grinding or neat ball milling. Our previous work demonstrated using FT-IR spectroscopy that a mechanochemical reaction had occurred in the mechanically treated neat mixtures. Herein is reported that microcrystal electron diffraction (microED) afforded the discovery of two diffracting micron-size particles in the amorphous powder synthesized by manual grinding, among a majority of non-diffracting particles. Remarkably, microED data of one of them led to the known lattice parameters of quininium aspirinate. Furthermore, this so-called 'X-ray amorphous' …

A Comparison Of Microcrystal Electron Diffraction And X-Ray Powder Diffraction For The Structural Analysis Of Metal-Organic Frameworks, Erik Biehler, Silvana Pagola, Daniel Stam, Johannes Merkelbach, Christian Jandl, Tarek M. Abdel-Fattah

Chemistry & Biochemistry Faculty Publications

This study successfully implemented microcrystal electron diffraction (microED) and X-ray powder diffraction (XRPD) for the crystal structure determination of a new phase, TAF-CNU-1, Ni(C₈H₄O₄)·3H₂O, solved by microED from single microcrystals in the powder and refined at the kinematic and dynamic electron diffraction theory levels. This nickel metal–organic framework (MOF), together with its cobalt and manganese analogues with formula M (C₈H₄O₄)·2H₂O with M = Mn ^II or Co^II, were synthesized in aqueous media as one-pot preparations from the corresponding hydrated metal chlorides and sodium terephthalate, as a promising `green' synthetic route to moisture-stable MOFs. The crystal structures of the …

An E. Coli Two-Hybrid System To Investigate Human Protein-Protein Interactions, Rebecca M. Richardson, Sarah M. Ho, Lane Tong, Morgan G. Daniels, Steven M. Pascal

Chemistry & Biochemistry Faculty Publications

Abstract

The LexA-E. coli two-hybrid (LexA-E2H) system was initially developed to study interactions between microbial proteins in an Escherichia coli (E. coli) environment. We here demonstrate its utility for studying mammalian protein interactions. Specifically, this study uses LexA-E2H to provide the first direct and quantitative validation of Glucose Regulated Protein 78 (GRP78) binding to the cleaved-Prostate Apoptosis Response 4 (cl-Par-4) tumor suppressor. Furthermore, the results establish that this interaction does not require phosphorylation of either protein. MacConkey agar was used for initial detection of the interaction through colorimetric colony screening, distinguishing pale white-pink colonies (+ interaction) from …

Protonic Capacitor Cell Energetics: Transmembrane-Electrostatically Localized Protons/Cations, James Weifu Lee

Chemistry & Biochemistry Faculty Publications

The transmembrane-electrostatically localized protons/cations charges (TELPs/TELCs) theory can serve as a theoretical framework to better explain cell electrophysiology and elucidate bioenergetic systems including both delocalized and localized protonic coupling. According to the TELCs model, the excess positive charges of TELCs at one side of the membrane are balanced by the excess negative charges of transmembrane-electrostatically localized hydroxides anions (TELAs) at the other side of the membrane. Through the TELCs-membrane-TELAs capacitor model, the energetics of oxidative phosphorylation have recently been better elucidated in mitochondria and alkalophilic bacteria, leading to the identification of a novel Type-B energetic process. Both the TELCs model …

Deciphering The Chemistry Of Condensed Aromatic "Black" Carbon And Nitrogen In Amazonian Anthrosols, João Vitor Dos Santos, Aleksandar I. Goranov, Laís G. Fregolente, Marcia C. Bisinoti, Zhenhuan Sun, Klaus Schmidt-Rohr, Patrick G. Hatcher

Chemistry & Biochemistry Faculty Publications

Amazonian anthrosols are renowned for their high fertility and dark color, properties primarily attributed to the abundance of condensed aromatic carbon (ConAC) in the soil organic matter. ConAC, commonly referred to as black carbon, play a key role in the stability and nutrient retention of these soils. However, the processes governing the formation of ConAC and its transformation into oxygenated derivatives remain poorly understood. In this study, we used multiple analytical platforms to investigate the chemistry of ConAC-rich humic acids (HA) extracted from Terra Mulata de Indio, a type of Amazonian anthrosol. The results reveal that ConAC are predominantly …

Application Of Telc Model To Better Elucidate Neural Stimulation By Touch, James Weifu Lee

Chemistry & Biochemistry Faculty Publications

Aim: This study is to better understand how the transient ion transport activity of touch receptors could change the graded potential to stimulate an action potential firing.

Methods: The latest transmembrane-electrostatically localized protons/cations charges (TELC) theory is employed for numerical analysis to calculate the neural touch signal transduction responding time required to fire an action potential spike.

Results: A neural action potential spike was constructed successfully using newly developed time-dependent TELC-based neural transmembrane potential integral equations (Equations 5, 6, and 7). The results explicated that the TELC curve has an inverse relationship with neural transmembrane potential since its curve appears …

Decoding Tattoo And Permanent Makeup Pigments: Linking Physicochemical Properties To Absorption, Distribution, Metabolism, And Elimination Profiles Using Quantitative Structure-Activity Relationship (Qsar)-Based New Approach Methodologies (Nams), Girija Bansod, Ajay Vikram Singh, Preeti Bhardwaj, Tulika Rai, Sweta Vijay Nakhale, Amruta Shelar, Rajendra Patil, Peter Laux, Andreas Luch, Christopher J. Osgood, Michael W. Stacey

Biological Sciences Faculty Publications

The safety and quality of tattoo and permanent makeup (PMU) pigments are subject to increased scrutiny due to their potential to cause adverse effects like anaphylaxis, photoallergic responses, and long-term toxicity. These undesirable reactions governed by their chemical structure possess varied physicochemical properties and absorption, distribution, metabolism, and elimination (ADME) characteristics. These properties control the pigment behavior during application, stability, and interaction with human tissue. The correlation between these physicochemical characteristics and ADME parameters of tattoo/PMU pigments remain under-explored despite the current advances in toxicology. Our study aims to address and bridge the gap by leveraging open-access QSAR computational toxicology …

Validating A Novel Capability Of Assessing Pathways Of Animal Water Gain And Loss, Zachary T. Steele, Karen Caceres, Zachary A. David, Lisa M. Shollenberger, Alexander R. Gerson, Seth D. Newsome, John P. Whiteman

Biological Sciences Faculty Publications

Understanding variations in the routes by which wild animals gain and lose water is challenging, and common methods require longitudinal sampling, which can be prohibitive. However, a new approach uses Δ′¹⁷O_BW (Δ′¹⁷O of animal body water), calculated from measurements of δ′¹⁷O and δ′¹⁸O in a single sample, as a natural tracer of water flux. Δ′¹⁷O_BW is promising, but its relationship to organismal variables such as metabolic rate and water intake have not been validated. Here, we continuously measured oxygen influxes and effluxes of captive deer mice (Peromyscus maniculatus), and manipulated their water intake and metabolic rate. We used …

Hair Growth Rate Estimation In North American Ursids, Jennifer H. Stern, Karyn D. Rode, Craig A. Stricker, Sheriden Ploof, Cindy L. J. Roberts, Celess Edinger, Mary Humbyrd, Nate Wagner, Megan A. Owen, John P. Whiteman, Thea Bechshoft, Brent White, Kristin L. Laidre

Biological Sciences Faculty Publications

The feeding ecology of wildlife populations has important implications for individual health, population productivity and distribution patterns. For ursids (bears), food resources and feeding behaviour primarily affect population dynamics via effects on cub production and survival. Much of what is known about the feeding ecology of bears is based on analyses of tissues collected from capture-based research efforts, harvested animals or non-invasive approaches. However, inference about diet from hair has been limited by a lack of quantitative data on the timing of the moult and hair growth rates. We conducted a study to develop and test two methods of quantifying …

The Association Between Food Benefit Online Ordering And Redemptions: Evidence From The Special Supplemental Nutrition Program For Women, Infants, And Children, Junzhou Zhang, Chuanyi Tang, Kayoung Park, Qi Zhang

Marketing Faculty Publications

Objective:

To examine how the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) online food benefit ordering could influence WIC benefit redemptions.

Design:

A cross-sectional study. We compare the average redemption rates between online ordering early adopters and non-adopters among WIC customers before and after implementing WIC online ordering. A propensity score-weighted difference-in-difference model was used to estimate the coefficients.

Setting:

The Oklahoma WIC programme and a grocery store chain in Oklahoma.

Participants:

12743 Oklahoma WIC households that had redeemed their food benefits at the grocery store chain in 2020.

Results:

WIC online ordering significantly positively affected redemption …

Emerging Nanotechnology Approaches For Blood Disorders: A Comprehensive Review Of Nano-Hematinics And Plant-Based Nanomedicines, Hassan Abdulsalam Adewuyi, Khairat Shamsudeen, Fatima Mahmoud Muhammad, Adeola Kolawole Victor, Sakariyau Adio Waheed, Adepeju Matilda Adekoya, Kashim Ibrahim Muhammad, Blessing Temitayo Longe, Abdulgaffar Abdulquddus

Chemistry & Biochemistry Faculty Publications

Background: Disorders affecting blood components, such as anemia, coagulopathies, and hematologic malignancies, continue to pose significant global health burdens. Traditional therapies often fall short due to adverse effects, limited bioavailability, and insufficient targeting of disease sites.

Objective: This review synthesizes current advances in nano-hematinics and plant-based nanomedicines (phyto-nanomedicines) as innovative strategies for managing blood-related conditions. These nanoscale interventions are designed to enhance therapeutic precision, bioactivity, and safety.

Methods: A systematic review was conducted using major scientific databases including PubMed, Scopus, Web of Science, and ScienceDirect. Search terms were carefully selected to retrieve literature published between 2015 and 2024 that discussed …

“Knowledge And Attitude Towards Ect Among The Caregivers Of Patients In A Tertiary Mental Health Care Setting”., Kajusree Borah, Arunjyoti Baruah Dr, Sandeep Kollipara

Manipal Journal of Nursing and Health Sciences

Background: Caregivers play an important role in shaping patients’ experiences with ECT. Despite evidence that ECT is an effective and safe treatment, certain factors, such as social stigma, inadequate knowledge, doubt about efficacy, and safety, have limited its use. With adequate knowledge, information, and understanding caregiver, as well as the patient, will develop a positive attitude towards it simultaneously. Aim: To assess the correlation of knowledge and attitude towards ECT among the caregivers of patients in a tertiary mental health care setting. Methodology: This study employed a descriptive correlational research design, conducted within a tertiary mental health care setting. …

Scientific Writing: A Guide From Data To Draft, Kristin M. Klucevsek

Open Education Materials

Textbook for ENGL302W (Scientific Writing)

CC BY-NC-SA (2025)

Speech-Language Pathologists’ Preparation To Become Clinical Educators, Alivia English

Master's Theses and Doctoral Dissertations

Clinical education is significant in a student clinician’s educational journey to prepare them for their career after graduation. It provides the hands-on component that can only be learned and fully understood through performing. The literature regarding students’ experiences in clinical education is vast, but there is a shortage of literature that explores the perceptions of clinical educators (CEs). This thesis consists of three articles. The first article explores the perceptions speech-language pathologists’ have regarding the preparation they received to become CEs, and then the second article takes a look at how the requirements to becoming CEs differ across similar clinical …

Designing A Narrative-Based Video Game For Adolescents Coping With A Parent's Cancer, Sophia Hamilton, Xubing Hao, Sharon Andrews, Eveyln Roldan, Carlos Martinez, Jane Hamilton, Muhammad Tuan Amith, Licong Cui

Faculty, Staff and Student Publications

We developed the narrative video game Sophia that immerses users in the story of a 13-year-old girl during her father's 18-month battle with glioblastoma and her journey toward resilience during her high school years following his passing. The game is designed to engage adolescents coping with parental cancer in multiple gameplay modes and levels, the character, and the outcome of the story as a way to build connections and explore the themes of illness, dying, bereavement, and resilience. The scenes at each level correspond to the stages of glioblastoma illness as well as the teenage milestones she passes through without …

The Psychological Impact Of Denied Blood Transfusions By Jehovah's Witness Parents In Pediatric Patients, Jaelyn Capablanca Braganza

Nursing | Student Research Posters

Jehovah's Witnesses believe that it is against God's will to receive blood from someone else, or to tamper with their own blood, influencing them to deny blood transfusions for themselves and for their children. Since minors are legally not allowed to make healthcare decisions on their own until they reach 18 years of age, this decision made by the parents to deny transfusions on the pediatric patient's behalf may create significant emotional and psychological challenges, potentially influencing family dynamics, mental health, and overall well-being. Understanding these effects, especially for the pediatric patient, is crucial for healthcare providers, social workers, and …

Improving Adherence In Adolescent Kidney Transplant Recipients, Kaylen Munoz

Nursing | Student Research Posters

Background: Adolescent and young adult (AYA) kidney transplant recipients face unique challenges in maintaining long-term graft function and overall health. Nonadherence to immunosuppressive therapy and difficulties transitioning from pediatric to adult care contribute to the increased risk of graft failure in this population. Despite proposed tools identifying adherence barriers, there is a lack of implementation and targeted interventions addressing the barriers AYA transplant recipients face. Purpose: This study aims to evaluate the effectiveness of a structured transition program that utilizes an adherence barrier tool and adherence-promoting interventions in improving health outcomes for adolescent and young adult (AYA) kidney transplant recipients. …

The Potential Of Bioactive Foods In Chemotherapy-Induced Gastrointestinal Distress, Haizhu Patterson

Nursing | Student Research Posters

Background: Cancer continues to have a profoundly detrimental impact on global health, and chemotherapy is widely accepted and utilized as one of the most effective cancer treatments. Unfortunately, the downside of chemotherapy is its significant adverse effects, which often manifest as gastrointestinal (GI) distress, leading the patient to discontinue treatment. Recent research has increasingly focused on bioactive foods as a means to mitigate chemotherapy-induced GI distress. By identifying which bioactive foods can alleviate these distresses, nurses can offer valuable recommendations to cancer patients to help them reduce chemotherapy's adverse effects, enhancing their quality of life (QoL) and improving treatment adherence. …

Awareness Of The Physiological Changes Occurring In Older Adults Can Reduce Dehydration And Electrolyte Imbalances, Lisa Isley

Nursing | Student Research Posters

Background: Individuals over 65 years are at an increased risk of dehydration. The physiological changes that occur with age and medication consumption can cause fluid and electrolyte imbalances that can physically and mentally impair individuals over 65 years old. Objective: By providing education to individuals 65 years and older regarding the significance of drinking water and consuming electrolytes daily, older adults can reduce their dehydration symptoms and improve their quality of life. Method: The proposed research is a quasi-experimental study geared towards individuals 65 years and older. The quasi-experimental study will include two pre-surveys and then two post-surveys. The survey …

Developing A Culturally Sensitive Nursing Framework For Muslim Patients Practicing Ramadan: Focusing On Fasting Benefits And Islamic Dietary Recommendations, Amreen Mahmood Munshi

Nursing | Student Research Posters

Background: Muslims practice Ramadan, a month-long period of fasting from dawn to dusk, yet many healthcare providers lack knowledge of its principles and practices. Hospitals lack formal education on caring for fasting Muslim patients, leading to a knowledge deficit in cultural competence and sensitivity of Islamic practices. Purpose: This paper proposes a research design for a nurse education program on Ramadan fasting to promote cultural competence and sensitivity in nursing care. The proposed research aims to educate nurses on Islamic practices, particularly Ramadan, to bridge the cultural competency gap. The literature review also explores the health benefits of …

Preparing For Loss: The Impact Of Hospital-Based Parental Death Preparation On Sibling Relationships, Elyssa Thea Cajilig

Nursing | Student Research Posters

No abstract provided.

The Impact Of Parental Mental Health On Infants In The Neonatal Intensive Care Unit, Andee L. Plaskett

Nursing | Student Research Posters

The neonatal intensive care unit (NICU) provides critical and life saving care for infants born with medical complications that may need specialized care. The NICU environment can be an overwhelming and stressful place for both parents and infants. Parental mental health challenges, such as stress, anxiety, and depression, can significantly impact infants in the NICU by hindering parent infant interaction and connection. Parental mental distress is often linked to an increase in anxiety for the infant, as well as higher rates of medical complications and a higher likelihood of longer hospital stays for the infant. Parental stress can have a …

Culturally Sensitive Nursing Care And Its Impact On Abuse Disclosure Among Immigrant-Origin Populations​, Jaspal Uppal

Nursing | Student Research Posters

Background: Immigrant-origin patients often face many systemic barriers when accessing healthcare. Factors such as language barriers, fear of deportation, limited trust in healthcare providers, and lack of culturally sensitive care make it hard for patients to disclose abuse. These challenges contribute to poor health amongst vulnerable populations which highlights the importance of using culturally sensitive and trauma-informed care. Objective: This research aims to test whether culturally adapted, trauma-informed nursing care improves disclosure of abuse and access to support services. The objective is to strengthen safety and trust between healthcare providers and patients through culturally sensitive care. Method: A quantitative quasi-experimental …

The Impact Of Diabetes Education & Post Discharge Interventions For African American Adults At Risk For & After Myocardial Infarction, Trinity L. Billingsley

Nursing | Student Research Posters

Cardiovascular disease or CVD refers to a multitude of conditions that affect both the heart and blood vessels. Being the leading cause of death in the United States, heart disease claims 919,032 lives; the risk of death becomes more likely when accompanied with comorbidities like diabetes (CDC, 2024). While heart disease is a leading cause of death across all populations, it accounts for a larger proportion of deaths in African American, or AA, adults at 22.6% compared to White adults at 18.0% and Hispanic adults at 11.9%, highlighting persistent racial disparities in cardiovascular outcomes (CDC, 2024). Diabetes as a comorbidity …

Exploring Dominican University Nursing Student’S Perceptions Of Economic Barriers To Accessing Essential Women’S Health Products, Annabelle E. Burke

Nursing | Student Research Posters

Access to essential feminine hygiene products, including menstrual supplies and hygiene items, is a growing economic and public health issue. Rising product prices and reliance on costly disposable products contribute to financial strain for many women. Period poverty is the lack of access to menstrual products, education, and hygiene facilities due to financial constraints, and it negatively affects women’s physical and mental health, particularly among students and low-income populations. Research shows that limited access to menstrual products affects dignity, sanitation, and emotional well-being and is compounded by social stigma and cultural silence surrounding menstruation (Brinkley & Niebuhr, 2023). Findings from …

The Effectiveness Of Botulinum Toxin Injections In The Management Of Chronic Neck And Shoulder Myofascial Pain: A Nursing Perspective, Jia Zhou

Nursing | Student Research Posters

No abstract provided.

The Psychosocial Effects Of Chemotherapy On The Adolescent Population: Implementing Community Building Programs, Kareena Jakhu, Princess Kyra R. Anicete

Nursing | Student Research Posters

Background: During the adolescent stage (13-18), individuals go through role confusion and seek much of their validation from their fellow peers. Forming a strong sense of community is crucial in this stage of development as it helps with creating a foundation for who they want to become. Chemotherapy strips this aspect of socialization due to its ability to suppress the immune system. When socialization is taken away, adolescents face loneliness, which greatly impacts their development. Purpose: The purpose of this research is to look into the adolescent population undergoing chemotherapy and help them aid the lack of socialization caused by …

The Role Of Sexual Assault Nurse Examiners: Addressing The Shortage And Its Implications For Healthcare, Isabel Mary Mccarthy

Nursing | Student Research Posters

The increasing prevalence of sexual assault cases has highlighted the crucial need for trained healthcare professionals who can effectively provide sensitive care for survivors. Sexual Assault Nurse Examiners (SANE) are registered nurses specifically trained to perform forensic examinations and provide medical and emotional support to sexual assault victims. However, many nursing programs lack formal education on SANE practices, which can hinder students' preparedness to address such cases in their future careers. This study aims to evaluate the effectiveness of a specialized Sexual Assault Nurse Examiner (SANE) training module integrated into an undergraduate nursing curriculum at Dominican University of California. By …