Medicine and Health Sciences Commons^™

When Elevated Creatinine Is Not What It Seems: Intraperitoneal Urinary Leak Mimicking Acute Kidney Injury, Hatem Ahmed, Mohamed K. Mansour, Hamza Obeid

Tower Health Research Day

No abstract provided.

Case Report: Non-Operative Management Of A Diaphragmatic Hematoma, Taylor Gong, Kendall Ozorowski, Davin Evanson, Michael Romeo

Tower Health Research Day

No abstract provided.

Tale Of A Colossal Heart: Coxsackie B Virus Related Dilated Cardiomyopathy Presenting As Ambulatory Cardiogenic Shock, Mahmood Danishwar, Muhammad Asad Hanif, Raesham Bukhari, Brian Mccauley

Tower Health Research Day

No abstract provided.

Finding A Leg To Stand On ; An Unexpected Case Of Anterior Ankle Pain Diagnosed By Pocus In A 48 Year Old Man ., Olawale Adeyemi Md,Mph, Madhulika Badri Bs

Tower Health Research Day

No abstract provided.

Transcatheter Repair Of Perivalvular Leak With A Ventricular Septal Defect Occluder In A Prosthetic Mitral Valve: A Case Report Of Recurrence And Challenges, Diane Lee, Mohammad Wajih Baig, Muhammad Mohsin Zafar, Muhammad Umer Riaz Gondal, Muhammad Ijaz Khan, Masroor Anwar, Michael Macciocca

Tower Health Research Day

No abstract provided.

Use Of Arrow Clarke Pleuraseal Thoracentesis Kit To Perform A Pericardiocentesis Emergency Medicine Physician Education Quality Improvement On High Acuity Low Occurrence Procedures, Kendall Higgins Md, Joshua Hamilton Do, Grant Nugent Md, Monisha Bindra Do, Shaila Quazi Do

Tower Health Research Day

No abstract provided.

Unlocking Prognostic Potential: Biomarker Predictors Of Admission And Length Of Stay In Pediatric Sickle Cell Vaso-Occlusive Pain Crisis, Jeffrey Hernandez, Abhishek Dutta, Jacob Lowry, Bruce Bernstein, Luis Gamboa, Nataly Apollonsky

Tower Health Research Day

No abstract provided.

Dyke-Davidoff-Masson Syndrome: A Rare Cause Of Drug Refractory Epilepsy In An Adult, Paresh Zanzmera, Vaidehi Chauhan, Tvisha Patel, Jaineel Patel, Ankit Dumaswala, Kinjal Shah

Tower Health Research Day

No abstract provided.

Trends In Pulmonary Embolism Mortality Amongst Pennsylvania Adults (1999-2020), Muhammad Umer Riaz Gondal, Zainab Kiyani, Anthony Donato

Tower Health Research Day

No abstract provided.

Applying Kolb's Theory Of Experiential Learning In The Development Of An Evidenced-Based Practice & Research Council At An Acute Care Hospital, Cheryl Green, Daryn Brauner Msn, Todd Allen Lane, Judy Darlucio Rn, Stacey Peace Rn

Medical Nursing

The processes of adult learning can become convoluted as adults age, developmentally progress through the life cycle, have different employment opportunities, and pursue academic studies. It is important when engaging adults in the learning of new content, that an eclectic approach to learning be implemented to ensure information is comprehended, applicable, and reproducible. Kolb’s Theory of Experiential Learning provides adult learners with four stages of learning; concrete experience, reflective observation, abstract conceptualization, and active experimentation. These four stages, applied separately and in combination of adult learning modalities, enhance the adult learning experience by introducing diverse approaches to the processing of …

The Present And Future Of Ai: Ethical Issues And Research Opportunities, Ankita Srivastava, Marco Marabelli, Danielle Blanch-Hartigan, Jeffrey Moriarty, Evan Carey

Computer Information Systems Faculty Publications

Healthcare is currently a fast-changing industry with AI and generative AI (GenAI) playing a prominent role in the transformation of clinical as well as managerial practices. Clinical practices involve AI to diagnose diseases and develop new drugs and compounds, while managerial practices concern AI-supporting processes such as billing patients and insurance companies, handling electronic medical records, and supporting remote connections with patients, increasingly using virtual and augmented reality. Yet, all these opportunities offered by AI come with challenges involving potential ethical issues, such as discrimination, bias, lack of accessibility, and privacy issues. In March 2024, we organized a panel with …

The Effect Of Transcutaneous Vagus Nerve Stimulation On Word Memory In Healthy Adults, Haylee Hurt, Cassandra Callahan, Olivia Galpin, Qiang Li

SACAD: Scholarly Activities

Transcutaneous vagus nerve stimulation (tVNS) is a non-invasive technique that has been demonstrated to reorganize the brain neural network based on neuroplasticity. Research shows that tVNS may enhance cognitive performance such as verbal memory, as it may elicit the release of key neurotransmitters, Gamma-aminobutyric Acid (GABA) and Noradrenaline, that modulate cognitive performance and learning. The current study hypothesizes that verbal memory as an important cognitive skill in healthy adults will be improved after receiving tVNS. Results showed that compared to the control group, participants in the experimental group improved their verbal memory manifested in faster reaction times and higher accuracy …

Ocular Surface Glycocalyx In Health And Disease, Rafael Martínez-Carrasco, Ajay Sharma

Pharmacy Faculty Articles and Research

The glycocalyx is a dynamic carbohydrate-enriched structure that forms a dense coating on the surface of animal cells, including those at the ocular surface. It plays a critical role in maintaining cellular functions and it has a significant influence in disease processes. At the ocular surface, glycoproteins such as mucins are essential for hydration, lubrication, and barrier protection. Proteoglycans and glycolipids contribute to cell signaling, and mediate interactions with pathogens. Alterations in the glycocalyx are implicated in a spectrum of ocular conditions, including dry eye disease, ocular allergies, infections, and systemic diseases such as Graft-versus-host disease (GVHD) and diabetes mellitus. …

Clinical Practice Guideline For Delirium Screening, Raji George

Walden Dissertations and Doctoral Studies

Summary This doctoral project developed a clinical practice guideline (CPG) to address the critical health issue of early identification of delirium among hospitalized high-risk patients. Hospital delirium is associated with prolonged hospital stay, increased nursing home or rehab use after hospitalization, and higher mortality. Evidence shows that systematic screening improves delirium identification among hospitalized high-risk adults. However, there was no clinical practice guideline for delirium screening at the project facility for high-risk, non-intensive care unit patients. Therefore, the practice-focused question for the project was, “Does the evidence support the development of a CPG for delirium screening in high-risk hospitalized patients …

Unveiling The Stigma: Doctor Mental Health And Intervention Strategies, Joseph Heirigs

Honors Program: Senior Projects (Public)

Background

The mental health of physicians is a pressing issue that has received increasing attention in recent years. The alarmingly high suicide rates for physicians underscores the critical need to address the mental health challenges that doctors face. Physicians are exposed to stressors that are unique to their profession, including high-stakes decision making, long work hours, traumatic patient situations, and the emotional toll of patient care. These challenges contribute to high rates of anxiety, depression, burnout, and other mental health issues. However, despite these factors, physicians are often reluctant to seek mental health treatment due to fears of professional repercussions, …

Effectiveness Of Intrapartum Azithromycin To Prevent Infections In Planned Vaginal Births In Low-Income And Middle-Income Countries: A Post-Hoc Analysis Of Data From A Multicentre, Randomised, Double-Blind Placebo-Controlled Trial, Waldemar A. Carlo, Alan T.N. Tita, Janet L. Moore, Musaku Mwenechanya, Elwyn Chomba, Jennifer J. Hemingway-Foday, Avinash Kavi, Mrityunjay C. Metgud, Shivaprasad S. Goudar, Richard J. Derman, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Jackie K. Patterson, Poonam Shivkumar, Manju Waikar, Archana Patel, Patricia L. Hibberd, Paul Nyongesa, Fabian Esamai, Osayame Austine Ekhaguere, Sherri Bucher, Saleem Jessani, Shiyam Sunder Tikmani, Sarah Saleem, Robert L. Goldenberg, Sk Masum Billah, Ruth Lennox, Rashidul Haque, William Petri, Manolo Mazariegos, Nancy F. Krebs, Denise C. Babineau, Elizabeth M. Mcclure, Marion Koso-Thomas, A-Plus Trial Group

Global Health Articles

Background

In 2023, the Azithromycin Prevention in Labor Use (A-PLUS) trial showed intrapartum azithromycin reduces maternal sepsis or death in women with planned vaginal delivery in low-resource settings, but whether it reduces maternal infection is unknown. We aimed to evaluate the effectiveness of intrapartum azithromycin in reducing maternal infection.

Methods

We performed a post-hoc analysis of the multicentre, facility-based, randomised, double-blind, placebo-controlled A-PLUS trial. This trial compared prophylactic intrapartum single oral dose of 2 g azithromycin versus placebo on maternal morbidity and mortality in low-resource settings in southeast Asia and Africa from Sept 9, 2020, to Aug 18, 2022. The …

Cost-Effectiveness Of Intrapartum Azithromycin To Prevent Maternal Infection, Sepsis, Or Death In Low-Income And Middle-Income Countries: A Modelling Analysis Of Data From A Randomised, Multicentre, Placebo-Controlled Trial, Jackie K. Patterson, Simon Neuwahl, Sydney Kirsch, Janet L. Moore, Alan T.N. Tita, Waldemar A. Carlo, Adrien Lokangaka, Antoinette Tshefu, Musaku Mwenechanya, Elwyn Chomba, Avinash Kavi, Mrityunjay C. Metgud, Shivaprasad S. Goudar, Richard J. Derman, Poonam Shivkumar, Manju Waikar, Archana Patel, Patricia L. Hibberd, Paul Nyongesa, Fabian Esamai, Osa A. Ekhaguere, Sherri Bucher, Saleem Jessani, Shiyam S. Tikmani, Sarah Saleem, Blair J. Wylie, Robert L. Goldenberg, Sk Masum Billah, Ruth Lennox, Rashidul Haque, William A. Petri, Manolo Mazariegos, Nancy F. Krebs, Jennifer J. Hemingway-Foday, Denise Babineau, Marion Koso-Thomas, Elizabeth M. Mcclure, Melissa Bauserman

Global Health Articles

BACKGROUND: Sepsis is one of the leading causes of maternal mortality globally. In 2023, the Azithromycin Prevention in Labor Use (A-PLUS) trial showed intrapartum azithromycin for women planning a vaginal birth reduced the risk of maternal sepsis or death and infection. We aimed to evaluate the cost-effectiveness of intrapartum azithromycin for pregnant people planning a vaginal birth in low-income and middle-income countries (LMICs) using A-PLUS trial data.

METHODS: We compared the benefits and costs of intrapartum azithromycin versus standard care across 100 000 model simulations using data from the A-PLUS trial and a probabilistic decision tree model that included 24 …

Bh3 Mimetics Augment Cytotoxic T Cell Killing Of Acute Myeloid Leukemia Via Mitochondrial Apoptotic Mechanism, Kapil Saxena, Shao-Hsi Hung, Esther Ryu, Shailbala Singh, Qi Zhang Tatarata, Zhihong Zeng, Zhe Wang, Marina Y Konopleva, Cassian Yee

Faculty, Staff and Student Publications

Adoptive cell therapy (ACT) can address an unmet clinical need for patients with relapsed/refractory acute myeloid leukemia (AML), but its effect is often modest in the setting of high tumor burden. In this study, we postulated that strategies to lower the AML apoptotic threshold will augment T cell killing of AML cells. BH3 mimetics, such as venetoclax, are a clinically approved class of compounds that predispose cells to intrinsic apoptosis by inhibiting anti-apoptotic mitochondrial proteins. We explored the anti-leukemic efficacy of BH3 mimetics combined with WT1-specific CD8+ T cells on AML cell lines and primary samples from patients with a …

Evaluating The Role Of Traditional And Nontraditional Educational Resources In Point-Of-Care Ultrasound Training: A Cross-Sectional Survey Of Educator Preferences And Practices, Arthur Broadstock, Annahieta Kalantari, Almaz S. Dessie, Al'ai Alvarez, Resa E. Lewiss, Josie Acuna, Anthony Weekes, Kaylah Maloney, Uwe Stolz, Lori Stolz, Aalap Shah

Department of Emergency Medicine Faculty Papers

BACKGROUND: Recently, nontraditional educational resources like podcasts, blogs, and online media have gained prominence in medical education and are abundant within the field of point-of-care ultrasound (POCUS). However, the extent to which POCUS educators utilize online resources compared to traditional resources, like textbooks, journal articles, and in-person workshops, is unknown. We aim to define which types of educational resources are used and preferred by POCUS educators to teach trainees.

METHODS: An expert working group developed a survey aimed to characterize the types of materials used by POCUS educators and their perceived importance on a 6-point forced ranking scale. We administered …

Navigating Excellence: A Comprehensive Program Evaluation Of An Academic Clinical Nurse Educator Pilot Course, Rachel D. Marquart

DNP Projects

Background and Rationale: Clinical instructors play a key role in nursing education, yet clinical instructors have varying degrees of formal preparation for the role. These inconsistencies affect student outcomes and instructors’ ability to effectively teach, mentor, and evaluate students. To address this, Belmont University developed the Academic Clinical Nurse Educator Program online course. This project conducted a comprehensive program evaluation to assess its effectiveness.

Aim: This project evaluated the effectiveness, success, and sustainability of an online Clinical Nurse Educator and Preceptor course designed to prepare registered nurses to teach undergraduate students and new nurses in clinical settings.

Design …

Ai And Ot: Preparing Future-Ready Practitioners, Jensen R. Antilla, Nancy E. Krusen, Nicole Martino, Stacy Smallfield

Innovations in Health Sciences Education Journal

This is an abstract from the Spotlight on Scholarship event in 2025.

Simulating Vascular Emergencies In Robotic Surgery: Preparing Ob-Gyn Residents For Surgical Complications, Jami Monico, Macy Thonen, Lindsey Mcalarnen

Innovations in Health Sciences Education Journal

This is an abstract from the Spotlight on Scholarship event in 2025.

An Innovative Approach To Operating Room Simulation With Dental Hygiene Student Preparedness And Awareness: An Iexcel Interprofessional Pilot Project, Jane M. Broekemeier, Amanda Dolen, Lisa J. Moravec

Innovations in Health Sciences Education Journal

This is an abstract from the Spotlight on Scholarship event in 2025.

Exposure Of Tracheostomy Education Well-Received During Pre-Clinical Head And Neck Physical Exam Course, Tony Satroplus, Jayme Dowdall, Chris Bingcang, Tony Richa, Katie Geelan-Hansen Md

Innovations in Health Sciences Education Journal

This is an abstract from the Spotlight on Scholarship event in 2025.

Transitions Into Gme Program Leadership Roles In Neonatal-Perinatal Medicine: Opportunities For Improvement, Courtney Mclean, Jennifer M. Brady, Megan Gray, Erynn Bergner, C. Lydia Wraight

Innovations in Health Sciences Education Journal

This is an abstract from the Spotlight on Scholarship event in 2025.

Improving Information Literacy And Research Skill Instruction Through Peer Consultation, Kimberly Harp

Innovations in Health Sciences Education Journal

This is an abstract from the Spotlight on Scholarship event in 2025.

Fortify-Med: Fostering Ongoing Research Training In First-Year Medical Students, Colman Freel, Rebekah Rapoza, Troy Suwondo, Wenxian Zhou, Kaeli Samson, Jesse L. Cox, G. Talmon, Kari Nelson

Innovations in Health Sciences Education Journal

This is an abstract from the Spotlight on Scholarship event in 2025.

Β-Catenin Drives The Foxc2-Mediated Epithelial-Mesenchymal Transition And Acquisition Of Stem Cell Properties, Maria Castaneda, Petra Den Hollander, Steve Werden, Esmeralda Ramirez-Peña, Suhas V Vasaikar, Nick A Kuburich, Claire Gould, Rama Soundararajan, Sendurai A Mani

Faculty, Staff and Student Publications

Background: Aggressive forms of breast cancer, such as triple-negative breast cancer (TNBC), are associated with an increase in cancer cells that exhibit stem cell properties. The activation of the epithelial-mesenchymal transition (EMT) program, mediated by the transcription factor FOXC2, generates these stem-like cells. FOXC2 is linked to poor prognoses across various cancer types and is notably upregulated in TNBC, where it establishes and sustains these stem-like cells within the tumor population.

Methods: Here, we decode the pathways regulating FOXC2 activation using EMT-enriched cell line models. Stemness was assessed using mammosphere assays and mesenchymal markers by western blot. Expression …

Domain Communication In Bifunctional Proline Utilization A From Sinorhizobium Meliloti, Emma Bitterman

Honors Program: Senior Projects (Public)

The reduction potential of flavin bound to Sinorhizobium meliloti proline utilization A (SmPutA) is beneficial in providing vital information on enzyme activity and the active site environment. Flavin is crucial in biological metabolism such as aerobic respiration and other important processes like oxygen activation that are catalyzed by flavin-dependent enzymes. (4). In this study, we seek to determine whether the redox potential of SmPutA-bound flavin can be used to characterize potential long-distance communication and analyze the possibilities of inactivation reversibility. SmPutA is a large bifunctional enzyme that catalyzes the overall oxidation of proline to glutamate via two catalytic domains (1). …

Descriptive Analysis Of Student Diagnostic And Documentation Skill Development In A Low Fidelity Simulation In Psychiatric Nurse Practitioner Education, Nicholas Guenzel, Hongying Dai

Innovations in Health Sciences Education Journal

This is an abstract from the Spotlight on Scholarship event in 2025.