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Articles 27151 - 27180 of 325131
Full-Text Articles in Medicine and Health Sciences
The Moderating Effect Of Self-Efficacy On The Interaction Between The Patient-Provider Relationship And Medication Adherence, Jonas M. Manalo
The Moderating Effect Of Self-Efficacy On The Interaction Between The Patient-Provider Relationship And Medication Adherence, Jonas M. Manalo
2025 Spring Honors Capstone Projects - Archive
Older adults taking multiple medications are at high risk for experiencing adverse drug events that result in hospitalization. Nurses are one of the first points of contact for patients and serve as patient educators. Many factors influence medication adherence, such as the patient-provider relationship and patient self-efficacy. This study aims to assess what impact patient self-efficacy has on the interaction between the patient-provider relationship and medication adherence.
The sample comprises adults aged 50 or older taking five or more medications. The Medication Understanding and Use Self-Efficacy (MUSE) Scale was used to measure patient self-efficacy and the patient-provider relationship while the …
Postpartum Depression And Anxiety Between First-Time And Multiparous Mothers Of Infants In The Nicu, Jennifer L. Diaz-Miranda
Postpartum Depression And Anxiety Between First-Time And Multiparous Mothers Of Infants In The Nicu, Jennifer L. Diaz-Miranda
2025 Spring Honors Capstone Projects - Archive
Postpartum depression (PPD) and anxiety are significant concerns for mothers with infants in neonatal intensive care units (NICUs); yet the role of parity in shaping these experiences remains underexplored. This cross-sectional secondary analysis examined data from 82 NICU mothers (62 adults, 20 adolescents) using the Edinburgh Postnatal Depression Scale and anxiety subscale. Findings revealed that primiparas and adolescents exhibited higher depression scores and multiparas and adolescents were more likely to experience anxiety symptoms. Parity, however, was not found to be a significant factor capable of predicting PPD or anxiety but results highlight the importance of early screening, personalized mental health …
A New Approach: Evaluating The Effectiveness Of Artificial Intelligence Developments For Trauma Triage In The Emergency Department, William C. Anoka
A New Approach: Evaluating The Effectiveness Of Artificial Intelligence Developments For Trauma Triage In The Emergency Department, William C. Anoka
2025 Spring Honors Capstone Projects - Archive
Triage in emergent situations occurs when patients are assigned to areas of the hospital with different levels of care according to the perceived risks determined by their signs and symptoms. The variability of current triage protocols substantially increases the proportion of lower acuity patients who die unexpectedly due to improper risk stratification. However, recent artificial intelligence (AI) developments have been applied to trauma triage situations to improve accuracy and patient outcomes. To further evaluate the effectiveness of this new tool, this study used various AI models to assess the presenting assessments of multiple situations and determine the appropriate level of …
Stress And Burnout Among Icu Nurses, Jaspreet Kaur
Stress And Burnout Among Icu Nurses, Jaspreet Kaur
2025 Spring Honors Capstone Projects - Archive
Burnout is a significant occupational hazard for Intensive Care Unit (ICU) nurses. High patient acuity, staffing shortages, and long shift hours increase stress and diminish well-being among nurses, affecting patient care outcomes. This study examined the prevalence of stress and burnout among ICU nurses to identify contributing factors and potential interventions. An anonymous online survey was conducted among 110 ICU nurses, utilizing the Maslach Burnout Inventory (MBI) and the Perceived Stress Scale(PSS). Findings revealed that 42.5% of nurses reported high emotional exhaustion, while 37.5% felt they had little to no control at work. The most frequently cited workplace stressors were …
Maternal Depression And Covid-19: A Secondary Analysis Comparing Postnatal Depression Rates During And Before The Covid-19 Pandemic, Amanda A. Berney
Maternal Depression And Covid-19: A Secondary Analysis Comparing Postnatal Depression Rates During And Before The Covid-19 Pandemic, Amanda A. Berney
2025 Spring Honors Capstone Projects - Archive
The COVID-19 pandemic created increased psychological vulnerability across the globe through isolation, fear of infection, and misinformation from various sources, including social media. Women giving birth during the pandemic, therefore, may be extremely vulnerable psychologically. Per the World Health Organization, the years 2020 to mid 2021were designated as an intense time during the COVID-19 pandemic. Thus, the objective of this secondary analysis was to compare depression scores among women giving birth during these intense years and women giving birth before 2020. However, due to a small window of time and sample size, statistical analysis failed to find a correlation between …
Health Care Delivery Of Asthma In Health Care Systems Across The World: A Comparison Of Three Health Systems, Megan T. Hui
Health Care Delivery Of Asthma In Health Care Systems Across The World: A Comparison Of Three Health Systems, Megan T. Hui
2025 Spring Honors Capstone Projects - Archive
Asthma remains a significant health concern globally, with healthcare delivery varying across different systems. This study aims to compare asthma care within three healthcare system: the Beveridge model (United Kingdom), the Bismarck model (Switzerland), and the National Health Insurance model (Canada) focusing on cost, quality, and accessibility. This study used a systemic review, gathering published evidence from the Organization for Economic Cooperation and Development (OECD) Data Explorers that explicitly met eligibility criteria for asthma treatment and outcomes. Evidence from government reports, public health databases, and peer-reviewed literature were analyzed. Kissick’s Iron Triangle framework was applied to assess the inherent trade-offs …
Design And Implementation Of A Notification System For The Purpose Of Improving Communication Between Nurses And Patients, Aindrila Bhattacharya
Design And Implementation Of A Notification System For The Purpose Of Improving Communication Between Nurses And Patients, Aindrila Bhattacharya
2025 Spring Honors Capstone Projects - Archive
Communication is an important part of how nurses administer treatment to their patients. Without proper communication, it is difficult for the nurses to connect with their patients and vice versa. This paper will be going into some previous literature about communication between patients and nurses in general, communication with respect to pediatric patients and how notification systems have been implemented in the past. It will then discuss the methodology and implementation of a notification system for a medical app. The medical app is meant to facilitate communication from the side of the patient to the nurse, while the notification system …
The Value Of Home: The Covid-19 Pandemic’S Influence On Living Space, Mental Well-Being, And Design Adaptability, Grace E. Woodall
The Value Of Home: The Covid-19 Pandemic’S Influence On Living Space, Mental Well-Being, And Design Adaptability, Grace E. Woodall
2025 Spring Honors Capstone Projects - Archive
Grace Woodall, Architecture
Title: The Value of Home: The COVID-19 Pandemic’s Influence on Living Spaces, Mental Well-Being, and Design Adaptability
Faculty Mentor: Marisa Gomez Nordyke
The COVID-19 pandemic redefined how people worked, learned, socialized, and lived. This study examines how American young adults’ perceptions of home evolved during and after the isolating lockdowns. This work addressed how the COVID-19 experience altered home’s value in young adults, the spatial, mental, and experiential challenges of confined spaces during the lockdowns, and the architectural elements that responded to these shifts. By analyzing post-pandemic housing trends, a literature review of architecture, psychology, home design, …
Wild West Healthcare: Addressing Healthcare Disparities In Rural Texas, Alexis K. O'Neal
Wild West Healthcare: Addressing Healthcare Disparities In Rural Texas, Alexis K. O'Neal
2025 Spring Honors Capstone Projects - Archive
Rural communities in Texas face significant barriers to healthcare access, including geographic isolation, limited healthcare facilities, and shortages of healthcare providers, which exacerbate health disparities and contribute to poorer health outcomes (Bennett et al., 2019; Jafri et al., 2024). This study examines healthcare access disparities between rural and urban areas in Texas, focusing on the role of telehealth and its impact on vulnerable populations, such as older adults and cardiovascular patients. Regions of Texas were categorized into rural, metropolitan, and metroplex areas to analyze variations in healthcare outcomes and access. Rural areas, defined as those with populations under 200,000, struggle …
Gad-7 Screening In Middle School Students: Evaluating The Effectiveness On Referral Rate Scoping Review, Bailey Hall, Cara Dennis, Kayla Drennen-Ferguson, Pamela B. Taylor, Laura Reed Dnp, Aprn, Fnp-Bc, Cne
Gad-7 Screening In Middle School Students: Evaluating The Effectiveness On Referral Rate Scoping Review, Bailey Hall, Cara Dennis, Kayla Drennen-Ferguson, Pamela B. Taylor, Laura Reed Dnp, Aprn, Fnp-Bc, Cne
Doctor of Nursing Practice Projects
Purpose/Background
The prevalence of anxiety disorders among adolescents, mainly middle school-aged students, highlights the critical need for practical screening tools to support early detection and intervention. The Generalized Anxiety Disorder-7 (GAD-7) scale is widely utilized in various settings, but its efficacy in this specific population remains underexplored. This scoping review examines the use of the GAD-7 in middle school-aged students, evaluating its reliability, validity, and impact on referral rates to mental health services. The review also considers factors influencing anxiety and identifies gaps in current research.
Methods
Ten articles, published in peer-reviewed journals within the past decade and involving human …
Postpartum Depression Screening At First Year Well-Child Visits: Evaluating The Rate Of Maternal Ppd Detection, Chidera A. Speight, Bsn, Rn, Katherine Scarbrough, Bsn, Rn, Camille Jones, Bsn, Rn, Laura Reed, Dnp Fnp-C
Postpartum Depression Screening At First Year Well-Child Visits: Evaluating The Rate Of Maternal Ppd Detection, Chidera A. Speight, Bsn, Rn, Katherine Scarbrough, Bsn, Rn, Camille Jones, Bsn, Rn, Laura Reed, Dnp Fnp-C
Doctor of Nursing Practice Projects
Purpose/Background
Postpartum Depression (PPD) is a concerning mental health condition characterized by feelings of extreme sadness, exhaustion, and challenges with maternal-infant bonding. PPD effects mothers’ ability to adequately care for themselves and their newborns. Current research suggests that one in seven women experience symptoms of PPD as late as 12 months postpartum. Despite screening guidelines set forth by the American Academy of Pediatrics, 50% of mothers with PPD will not receive a diagnosis.
This study aims to evaluate the rate of PPD detection at well-child visits occurring within the first 12 months postpartum by administering the Edinburgh Postnatal Depression Scale …
Over-Imitation Skills In Children With Autism Spectrum Disorder Compared To Typically Developing Peers: An Expanded Literature Review, Josephine M. Stadler
Over-Imitation Skills In Children With Autism Spectrum Disorder Compared To Typically Developing Peers: An Expanded Literature Review, Josephine M. Stadler
Communication Disorders and Occupational Therapy Undergraduate Honors Theses
Abstract
Background:
Imitation, a foundational social and cognitive development mechanism, enables individuals to acquire cultural norms, communication skills, and problem-solving strategies. Over-imitation— the replication of both relevant and irrelevant actions demonstrated by others—plays a critical role in social learning. While typically developing children often engage in over-imitation to promote social bonding and affiliation, the role and underlying motivations for over-imitation in children with ASD remain less clearly understood.
Purpose:
Through a critical synthesis of professional and scholarly literature, this review aims to evaluate the history and development of research on imitation and over-imitation, assess empirical findings regarding typically developing children …
Examination Of Language Sample Analysis In Children Who Are D/Hh Using Clan, Caroline G. Stewart
Examination Of Language Sample Analysis In Children Who Are D/Hh Using Clan, Caroline G. Stewart
Communication Disorders and Occupational Therapy Undergraduate Honors Theses
Hearing is the building block of developing receptive and expressive oral language skills used to effectively communicate. Children who experience hearing loss typically experience delays in phonological, morphological, semantic, and even pragmatic development. Understanding the specific language challenges faced by deaf and hard of hearing (D/hh) young preschool-age children is crucial for developing targeted intervention strategies aimed at optimizing their language development. This research aims to analyze the nuanced aspects of phonological, morphological, semantic, and pragmatic language development among D/hh children, shedding light on areas that may require specialized support. The preliminary research will inform best practices in language assessment …
A Comparative Analysis Of Salt And Clan In The Context Of Analyzing Disfluencies In Preschool-Age Children Who Stutter, Addilin G. Brown
A Comparative Analysis Of Salt And Clan In The Context Of Analyzing Disfluencies In Preschool-Age Children Who Stutter, Addilin G. Brown
Communication Disorders and Occupational Therapy Undergraduate Honors Theses
This case study compares two widely used language sample analysis (LSA) programs including the Systematic Analysis of Language Transcripts (SALT) software and the Child Language Analysis (CLAN) software. The comparison aims to evaluate their effectiveness in analyzing the conversation-based language sample of a preschool-aged child who was reported at-risk for stuttering. A conversational language sample was collected from a four-year-old male at a local head-start program. The sample was transcribed and analyzed using both SALT and CLAN. SALT provided a user-friendly interface with clear results and a comparison to normative data. Some of these results included a maze and word …
Assessing Language Skills Of Children Within The Head Start Program Using Language Sampling Analysis, Lynley Bowen
Assessing Language Skills Of Children Within The Head Start Program Using Language Sampling Analysis, Lynley Bowen
Communication Disorders and Occupational Therapy Undergraduate Honors Theses
Fluency disorders, including stuttering and cluttering, disrupt one’s natural rate of speech and can cause implications for one’s emotional well-being. This study explores the relationship between language factors and stuttered events in preschool-age children by analyzing a spontaneous language sample using two transcription software programs, CLAN and SALT. A language sample was collected from a child enrolled in a local Head Start program and was transcribed and analyzed using the software programs. Results from CLAN’s KIDEVAL and FLUCALC features offered analysis of the child’s language profile, as well as SALT’s standards measure report feature. This study highlights the importance of …
Understanding The Impact Of Language Barriers And Visit Duration On Caregiver Satisfaction In Pediatric Primary Care, Gavin Miller
Understanding The Impact Of Language Barriers And Visit Duration On Caregiver Satisfaction In Pediatric Primary Care, Gavin Miller
Health, Human Performance and Recreation Undergraduate Honors Theses
Background: Children from households that speak languages other than English (LOE) face barriers in accessing healthcare, leading to poorer health outcomes. Language barriers contribute to these disparities, often resulting in diminished communication between providers and families. Visit duration may play a key role in facilitating effective communication and improving patient satisfaction.
Purpose: This study examines how language barriers affect caregiver satisfaction in pediatric primary care, and whether visit duration mediates this relationship. We hypothesized that caregivers from LOE households would have comparable visit durations to English-preferring caregivers but report lower satisfaction due to receiving less information within that time. …
The Fraught Path To Residency For International Medical Graduates, Fatima Mossolem, Nidhi Chaudhary, Kate Whelihan, Venkat Venkataraman
The Fraught Path To Residency For International Medical Graduates, Fatima Mossolem, Nidhi Chaudhary, Kate Whelihan, Venkat Venkataraman
Rowan-Virtua Research Day
Background:
International medical school graduates (IMGs) are a vital part of the physician workforce in the United States helping to combat the ongoing physician shortage. The Association of American Medical Colleges reported that 42.3% of hospitalists were IMGs, physicians that also comprise a significant part of primary care physicians in rural underserved areas. Students in a gray area of immigration statuses such as those in DACA or those that have lived in the US for years waiting to attain citizenship are automatically considered “international students” and have typically received less residency interviews, and have had a harder time matching into …
Comparison Of Graft Patency Between Sta, Ra, And Sv Grafts Of Intracranial Aneurysms Of The Internal Carotid Artery, Nassos Tziviskos, Hallie Tiburzi, Susrut Dube
Comparison Of Graft Patency Between Sta, Ra, And Sv Grafts Of Intracranial Aneurysms Of The Internal Carotid Artery, Nassos Tziviskos, Hallie Tiburzi, Susrut Dube
Rowan-Virtua Research Day
Abstract
Background: Patients with intracranial internal carotid artery (ICA) aneurysms that are not amenable to treatments like coiling, stenting, or clipping have limited treatment options. One option is vascular bypass of the aneurysm to introduce a stable route for cerebral perfusion, which can be performed using the superficial temporal artery (STA) or alternatively radial artery (RA) or saphenous vein (SV) grafts, among other vessels.
Methods: The major databases were searched to identify studies that explored graft patency and functional outcome for patients who underwent bypass for intracranial ICA aneurysms with STA, RA, or SV grafts and proportion meta-analysis was performed. …
Establishing The Dose-Response Effect Of Myofascial Release On Muscle Physiology, Sanjana Davuluri, Seth Spicer, Tyler Pigott
Establishing The Dose-Response Effect Of Myofascial Release On Muscle Physiology, Sanjana Davuluri, Seth Spicer, Tyler Pigott
Rowan-Virtua Research Day
Context: Osteopathic manipulative treatment (OMT) is often indicated for back pain due to its high tolerability and post-treatment improvement in patients’ self-reported pain and functionality. Specifically, myofascial release (MFR) has been found to yield a significant improvement in both symptoms and quality of life. Until recently, there has not been much data published about the quantifiable effect of MFR and other OMT modalities on muscle physiology, especially taking treatment dose and force into consideration. Therefore, quantifying the changes in muscle characteristics through myotonometry would greatly benefit the field of osteopathic medicine in order to create more personalized treatment plans …
Affordable Architecture: Promoting Mental Health Through Cost-Effective Design In Underfunded High Schools In Dallas-Fort Worth, Raphaella Malicay
Affordable Architecture: Promoting Mental Health Through Cost-Effective Design In Underfunded High Schools In Dallas-Fort Worth, Raphaella Malicay
2025 Spring Honors Capstone Projects - Archive
Mental health awareness has increased over the years as well as numerous strategies to support mental health. Some of these strategies include addressing the built environment. This paper explores the intersection between mental health and the built environment through the lens of affordable architectural methods that would be effective in underfunded secondary schools. This study examines how architecture influences students’ well-being and how certain design strategies can be implemented even in schools that lack the financial resources for adequate infrastructure. Here the focus is on investigating affordable solutions such as improving ventilation, optimizing natural light, having flexible learning spaces, and …
A Review Of Studies Assessing Modifiable Risk Factors For Dementia Among Family Caregivers In The United States Based On Behavioral Risk Factorsurveillance System (Brfss), Shruthi Ranjithkumar
A Review Of Studies Assessing Modifiable Risk Factors For Dementia Among Family Caregivers In The United States Based On Behavioral Risk Factorsurveillance System (Brfss), Shruthi Ranjithkumar
2025 Spring Honors Capstone Projects - Archive
Caregivers of individuals with Alzheimer's Disease and Related Dementia (ADRD) face an increased risk of developing dementia due to advanced age and modifiable risk factors. The 2024 Lancet Commission Report identified 14 such risk factors, whose mitigation could reduce dementia cases by 45%. Despite this, research on modifiable dementia risk factors among ADRD caregivers remains limited. This study investigates whether peer-reviewed studies utilizing Behavioral Risk Factor Surveillance System (BRFSS) data assess modifiable dementia risk factors among ADRD caregivers. A PubMed search retrieved 27 relevant articles, which were analyzed for risk factors identified by the Lancet Commission, including traumatic brain injury, …
Exploring Spatial Arrangements And Smart Technology To Manage Cognitive Load In Kitchens For Aging In Place, Monique Chabot
Exploring Spatial Arrangements And Smart Technology To Manage Cognitive Load In Kitchens For Aging In Place, Monique Chabot
Full-Text Theses & Dissertations
Older adults undergo natural physiological changes in various physical and cognitive functions, including balance, strength, memory, attention, and executive functioning. Memory, attention, and executive functioning integrate to form functional cognition, a skill that allows people to safely and efficiently complete daily tasks. Functional cognition is integral to the ability to age in place and is sensitive to demands in the environment. While a decline in some cognitive functions is expected with age, it is not typically observable except in the presence of pathological conditions or situations of cognitive overload from complex tasks or high environmental demands.
Older adults have identified …
Depression, Anxiety, And Suicide Among Adolescents: Sex Differences And Future Perspectives, Giovana V.R. Toro, Paula Arias, Alejandro De La Torre-Luque, Jonathan B. Singer, Natalia Lagunas
Depression, Anxiety, And Suicide Among Adolescents: Sex Differences And Future Perspectives, Giovana V.R. Toro, Paula Arias, Alejandro De La Torre-Luque, Jonathan B. Singer, Natalia Lagunas
Social Work: School of Social Work Faculty Publications and Other Works
Depression and anxiety are two disorders that significantly increase the risk of suicidal behavior. The disparity between females and males in the prevalence of these disorders becomes more pronounced from adolescence onwards. Specifically, risk factors associated with suicidal behavior in adolescent females are often linked to anxiety and depression, whereas in males, these behaviors are more frequently associated with other types of disorders, such as disruptive behavior. Furthermore, there are notable sex differences in the efficacy and acceptance of treatments aimed at preventing suicidal behavior. This review examines the sex differences in the relationship between depression, anxiety disorders, and suicidal …
Pd-L1 Testing, Treatment Patterns, And Clinical Outcomes Among Patients With Metastatic Nsclc At An Academic Medical Center, 2017-2021., Mehmet Altan, Dawen Sui, Cai Xu, George R Simon, Saliha T Sulihem, Donna Malveaux, Darcy Ponce, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, J Jack Lee, Jianjun Zhang, Don L Gibbons, Ara A Vaporciyan, John V Heymach, Melissa L Santorelli, Thomas Burke, Loretta A Williams
Pd-L1 Testing, Treatment Patterns, And Clinical Outcomes Among Patients With Metastatic Nsclc At An Academic Medical Center, 2017-2021., Mehmet Altan, Dawen Sui, Cai Xu, George R Simon, Saliha T Sulihem, Donna Malveaux, Darcy Ponce, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, J Jack Lee, Jianjun Zhang, Don L Gibbons, Ara A Vaporciyan, John V Heymach, Melissa L Santorelli, Thomas Burke, Loretta A Williams
Oncology Articles
INTRODUCTION: Targeted therapies and immune checkpoint inhibitors (ICIs) have revolutionized the management of metastatic non-small cell lung cancer (NSCLC) over the past decade.
METHODS: This single-center observational study was conducted to describe programmed death-ligand 1 (PD-L1) testing, choice of therapy, and outcomes for adult patients with stage IV NSCLC initiating first-line therapy from 2017 through 2020, with follow-up through June 2021. Patient characteristics and study assessments were described according to four histomolecular subtypes, defined by histologic characteristics and availability of standard-of-care therapies for molecular subgroups at the time of study conduct.
RESULTS: Of 507 eligible patients with metastatic NSCLC, 85 …
Bioavailability Of Lead In Terre Haute Soils, Terre Haute, Indiana, Zach Kemp
Bioavailability Of Lead In Terre Haute Soils, Terre Haute, Indiana, Zach Kemp
All-Inclusive List of Electronic Theses and Dissertations
Contamination of soils from heavy metal pollution has been a global concern for decades. Heavy metals are released into the soil from natural and anthropogenic releases. The largest producers of heavy metal pollution include mining, industrial production, and the combustion of fossil fuels. Vigo County formed in 1818, and Terre Haute was established in 1832. After the discovery of coal in Clay County in 1867, Terre Haute became the third largest coal producer and fifth largest iron manufacturer in the state during that time. Lead, in particular, is a heavy metal of concern because of the harmful effects to humans …
The Impact Of Quality Of Life And Recovery Capital On Inhibitory Control In Patients On Medication For Opioid Use Disorder, Caroline K. Jeffries
The Impact Of Quality Of Life And Recovery Capital On Inhibitory Control In Patients On Medication For Opioid Use Disorder, Caroline K. Jeffries
All Theses
The opioid crisis persists as a global health challenge, necessitating a comprehensive understanding of the complex interplay between psychological factors and neurocognitive responses among individuals with opioid use disorder (OUD). Two such psychological factors include recovery capital, an individual's internal and external resources to supporting recovery, and quality of life. Past work suggests that positive levels of recovery capital and quality of life may enhance individuals’ ability to regulate emotions and manage cravings. However, it is unclear how these variables are affected when buprenorphine is taken. This study investigates the influence of recovery capital and quality of life on inhibitory …
A Review On Treatment, Prevention, And Research Of Worldwide Parasitic Disease: Toxoplasmosis, Hannah Skinner
A Review On Treatment, Prevention, And Research Of Worldwide Parasitic Disease: Toxoplasmosis, Hannah Skinner
All Theses
Toxoplasmosis is a worldwide, yet often overlooked, parasitic disease caused by the protozoan parasite, Toxoplasma gondii. The parasite is capable of infecting humans and almost all warm-blooded vertebrates. Over a million people are infected in the United States with toxoplasmosis each year. Most infections are asymptomatic but severe cases can lead to vision impairment, neurological disorders, and congenital birth defects. T. gondii is transmitted through undercooked meat, infected feline feces, or contaminated water and soil. The burden of T. gondii infection is most notable in livestock, felines, and immunocompromised humans. Despite being a widespread disease, toxoplasmosis is neglected in …
Efficacy Of Platelet Rich Plasma On Thumb Basal Joint Osteoarthritis: A Narrative Review, Vrushank Shah, Alexander King
Efficacy Of Platelet Rich Plasma On Thumb Basal Joint Osteoarthritis: A Narrative Review, Vrushank Shah, Alexander King
Rowan-Virtua Research Day
Platelet-rich plasma (PRP) has emerged as a potential treatment for carpometacarpal (CMC) joint osteoarthritis, with studies suggesting it may offer more durable symptom relief compared to corticosteroids. A comprehensive review of four studies, including two randomized controlled trials (RCTs), a retrospective study, and a pilot study, revealed that both PRP and corticosteroid injections led to short-term improvements in pain and function. However, PRP demonstrated significantly better long-term outcomes, with VAS scores decreasing from 75 to 20 in the PRP group at 12 months, compared to a modest reduction from 70 to 65 in the corticosteroid group. Additionally, PRP showed a …
Personalizing Intermittent Fasting: The Role Of Microbiome Diversity And Fiber Intake In Shaping Health Outcomes, Jana Gjini, Robin Moore, Venkateswar Venkataraman
Personalizing Intermittent Fasting: The Role Of Microbiome Diversity And Fiber Intake In Shaping Health Outcomes, Jana Gjini, Robin Moore, Venkateswar Venkataraman
Rowan-Virtua Research Day
BACKGROUND: Intermittent fasting (IF) has been linked to improved metabolic health, reduced inflammation, and increased longevity in animal models. These effects are thought to be mediated through changes in the gut microbiome. Murine studies consistently show that IF enhances microbial diversity and promotes beneficial species like Lactobacillus and Bifidobacterium, improving metabolic profiles and gut barrier function. However, human studies reveal inconsistent results, suggesting that individual-level factors such as baseline microbiome composition and fiber intake may influence response to IF.
HYPOTHESIS: Baseline gut microbiome diversity and habitual dietary fiber intake modulate the metabolic and inflammatory benefits of intermittent fasting in humans. …
Effects Of Novel Dopamine D4 Receptor-Targeted Compounds On Locomotor Activity And Anxiety-Like Behavior In Male And Female Sprague Dawley Rats, Samantha Alyse Walkow, Noah A. Ivak, Daniel Chandler, John Tkaczynski, Thomas M. Keck, Comfort A. Boateng, Eleni Papadopoulos, Barry D. Waterhouse, Rachel L. Navarra
Effects Of Novel Dopamine D4 Receptor-Targeted Compounds On Locomotor Activity And Anxiety-Like Behavior In Male And Female Sprague Dawley Rats, Samantha Alyse Walkow, Noah A. Ivak, Daniel Chandler, John Tkaczynski, Thomas M. Keck, Comfort A. Boateng, Eleni Papadopoulos, Barry D. Waterhouse, Rachel L. Navarra
Rowan-Virtua Research Day
The consequences of modulating subtypes of G protein coupled dopamine receptors are broadly studied for their role in decision making behavior, specifically in situations involving uncertain risk and reward. The actions of dopamine D4 receptors (D4Rs) on these complex processes are the least understood, particularly due to a lack of available compounds with suitable selectivity for D4Rs. Further, current research often fails to evaluate how modulating specific dopamine receptor subtypes may affect locomotor activity and anxiety-like behavior as confounding factors prior to assessing their function in behavioral assays of higher order decision making. The goal of the current study was …