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Full-Text Articles in Medicine and Health Sciences

Water-Associated Bacterial Infection Without Aquatic Exposure, Meghan Glaser, Ashley Armstrong, Justin Skrzynski May 2025

Water-Associated Bacterial Infection Without Aquatic Exposure, Meghan Glaser, Ashley Armstrong, Justin Skrzynski

Conference Presentation Abstracts

Introduction: Shewanella algae is a gram-negative, facultatively anaerobic bacterium most commonly found in marine environments. It is an emerging human pathogen, most often associated with hepatobiliary and skin and soft tissue infections (SSTI) following water exposure. Known risk factors for infection include those participating in recreational water activities, flood victims, and those with underlying liver disease, immunosuppression, or IV drug use. This case involves a 70-year-old male who was involved in a motor vehicle accident in 2008 leading to multiple orthopedic surgeries complicated by recurrent prosthesis infections who presented with concern for sepsis. Case Description: Patient is a 70-year-old male …


An Integrative, Holistic Treatment Approach For Veterans With Chronic Traumatic Brain Injury And Associated Comorbidities: Case Report, Rebekka Dieterich-Hartwell, Janine Brodovsky, Kathryne Dealba, Allison Rubin, Emily Mcguigan, Bindal M. Mehmel, Yevgeniya Sergeyenko May 2025

An Integrative, Holistic Treatment Approach For Veterans With Chronic Traumatic Brain Injury And Associated Comorbidities: Case Report, Rebekka Dieterich-Hartwell, Janine Brodovsky, Kathryne Dealba, Allison Rubin, Emily Mcguigan, Bindal M. Mehmel, Yevgeniya Sergeyenko

Moss-Magee Rehabilitation Papers

This case report of a veteran with a history of multiple traumatic brain injuries, posttraumatic stress, and chronic pain highlights the MossRehab Institute for Brain Health (MRIBH) model of care: a collaborative, interdisciplinary, intensive outpatient treatment program. Unique to this case was the severity of symptomatology and the concerted engagement by the clinicians, who fully tailored and adjusted their approaches based on team rounds and daily exchanges. The client's main concerns of headaches, difficulty sleeping, difficulty with memory and cognition, depression, anxiety, posttraumatic stress, anger, and chronic musculoskeletal pain were addressed and significantly improved within three weeks. The outcome of …


A Single Center Qualitative Study To Improve Coordination Of Follow-Up Care For Patients Diagnosed With Abusive Head Trauma, Ruairi Smith-Dewey, Elise Wright, Daniella Donofrio, Hannah Goebel, Sara Kilbride May 2025

A Single Center Qualitative Study To Improve Coordination Of Follow-Up Care For Patients Diagnosed With Abusive Head Trauma, Ruairi Smith-Dewey, Elise Wright, Daniella Donofrio, Hannah Goebel, Sara Kilbride

Posters

Introduction: Children diagnosed with abusive head trauma (AHT) have subsequent long-term developmental, behavioral, and medical consequences resulting in increased medical system utilization. There were 16 overall potential needs identified, with a single patient having 12. In 2023 at Children’s Mercy Hospital (CMH), 47% (8/17) of patients with AHT had < 50% of follow-up needs addressed at time of discharge. None had 100% of follow-up needs addressed. Needs not being addressed included need not identified or written documentation for need of follow-up without subsequent referral placed/appointment scheduled. Project goal was all follow-up needs to be addressed for at least 50% of children with AHT by January 2025. Methods (include PDSA cycles): Children admitted to CMH from January 2024-December 2024 and diagnosed with AHT by the Safety, Care & Nurturing (SCAN) team were included. Interventions were designed and implemented by a multidisciplinary team to address barriers including variation in scheduling process per specialty, lack of knowledge, and changing caregivers. • PDSA 1 (1/1/24): SCAN added standardized list of potential follow-up needs to documentation. • PDSA 2 (2/1/24): Trauma NP placed ophthalmology outpatient referrals. • PDSA 3 (3/1/24) Social work placed and documented early intervention referrals. Transitioned to SCAN RN responsibility. • PDSA 4 (4/10/24): AHT caregiver handouts with description of all potential follow-up needs added to discharge instructions. • PDSA 5 (12/11/24): AHT Evidence Based Practice guideline created including follow-up needs. Appointments and referrals were tracked by the author. QI tools used included fault tree, fishbone, and PICK Chart. Results: In 2024, 27 children were diagnosed with AHT by SCAN team at CMH. Five children were excluded from the study as 3 died and 2 were transferred to another hospital. The number of patients with < 50% of follow-up needs addressed was reduced from 47% to 43%. All follow-up needs were addressed in 13% (3/23) of patients. Conclusions: While project aims weren’t met, there was progress. Next steps include educating all discharging teams at CMH as there is no single team discharging these patients. Overall, there are few of these patients so standardization of discharge practices is challenging. SCAN created a working group and point person for appointment tracking to ensure follow-up needs established at discharge.


Implementing Lean Methodology To Decrease Wait Times In A Psychiatric Emergency Department, Kristina S. Baxter May 2025

Implementing Lean Methodology To Decrease Wait Times In A Psychiatric Emergency Department, Kristina S. Baxter

Doctor of Nursing Practice Final Project Abstract

Purpose

This quality improvement project aimed to implement Lean strategies to optimize the intake process in a psychiatric emergency department, thereby reducing patient wait times, minimizing left-without-being-seen (LWBS) occurrences, and improving access to timely psychiatric care.

Background

The project was conducted in a hospital-based psychiatric emergency department in Southeast Texas, serving adults and children six years and older.

Methodology

Lean methodology and PDSA cycles were employed to refine the intake process and eliminate inefficiencies. Key interventions included patient transport by technicians to minimize delays, using tele-clinicians for assessments to reduce staff burden, and restructuring nursing assessments to prioritize telehealth consultations …


Evaluation Of The Library Session In A Health System Rn Research Fellowship Program, Frances Chu, Basia Delawska-Elliott, Carrie Grinstead, Dana Kopp, Heather Martin May 2025

Evaluation Of The Library Session In A Health System Rn Research Fellowship Program, Frances Chu, Basia Delawska-Elliott, Carrie Grinstead, Dana Kopp, Heather Martin

Articles, Abstracts, and Reports

No abstract provided.


A Storm Within: Anti-Nmda Receptor Encephalitis Mimicking Anxiety In A Young Woman, Izma Khaliq, Omar Sami Abdelhai, Angela Ishaq, Emmanuel Meram, Anointing Onuoha, Ahmed Jabri, William Dillon May 2025

A Storm Within: Anti-Nmda Receptor Encephalitis Mimicking Anxiety In A Young Woman, Izma Khaliq, Omar Sami Abdelhai, Angela Ishaq, Emmanuel Meram, Anointing Onuoha, Ahmed Jabri, William Dillon

Conference Presentation Abstracts

Case Description: A 21-year-old female with a history of asthma presented to the emergency department (ED) with restlessness, anxiety, and loss of appetite shortly after returning from a trip to France, where she and her boyfriend ended their relationship. Her initial evaluation, including unremarkable laboratory results, led to the attribution of her symptoms to anxiety from life stressors. She was treated with supportive measures in the ED and prescribed Xanax by her primary care physician at follow-up. Six days later, the patient returned to the ED with hallucinations and panic attacks. Again, laboratory results were unremarkable, and she was diagnosed …


Raised Spirits The Visceral Journey Of Black Generational Female Trauma And The Transcendent Healing Power Of Spiritual Dance, Wendy Ann Powell May 2025

Raised Spirits The Visceral Journey Of Black Generational Female Trauma And The Transcendent Healing Power Of Spiritual Dance, Wendy Ann Powell

Theses and Dissertations

Black female bodies have endured sustained trauma globally since the transatlantic slave trade, and it continues into 2025. The collective consciousness has carried the generational burden and mobilized it within the womb. Powell uses this intergenerational knowledge to frame the basis for spiritual dance practices as a healing praxis.


One Can Only Dream, Sophia V. Yacca May 2025

One Can Only Dream, Sophia V. Yacca

Theses and Dissertations

One Can Only Dream is an interactive installation in which players are invited to navigate a liminal, dream-like game, engage with a branching series of questions, and introspect upon the relationships between unconscious expression, conscious self-perception, and the inherent difficulty of depicting, sharing, and understanding subconscious thought.

Rooted in both my personal experience with a rare neurophysiological condition and in my desire to create, this project examines dreams not only as a medical and cultural phenomenon, but also as a means to form identity, reflect trauma, and inspire creativity. Drawing from modern interactive storytelling and my lived experiences, this work …


Behavioral Responses To The Medicare Part D Coverage Gap And Its Closure, Selene Urbatsch May 2025

Behavioral Responses To The Medicare Part D Coverage Gap And Its Closure, Selene Urbatsch

Theses and Dissertations

The author examines how exposure to the Medicare Part D coverage gap affects future prescription drug use and whether the closure of the gap under the Affordable Care Act (ACA) altered beneficiary behavior. Using 2007–2019 MEPS data, the analysis compares Part D enrollees to similarly aged, privately insured individuals, producing first-differences and difference-in-differences estimates. Before the ACA, exposure to the gap was associated with 4.9 fewer prescription fills relative to comparable non-Part D individuals. After the ACA, the effect fell to a reduction of 2.2 generic fills, with no significant decline in branded use. Sudden out-of-pocket cost increases prompted sharp …


Out From Under: Stories Of Endometriosis, Prisca Edwards May 2025

Out From Under: Stories Of Endometriosis, Prisca Edwards

Theses and Dissertations

Six individuals. One diagnosis. In Out From Under, people living with endometriosis gather for an art-centered workshop. Through collage and conversation, they transform isolating medical experiences into paths of connection and collective healing.

Endometriosis affects approximately one in ten women of reproductive age, yet diagnosis is often delayed by nearly a decade. During this time, many suffer from debilitating symptoms without adequate care or accessible treatment. Out From Under explores the lived experience of endometriosis through the lens of socially engaged documentary filmmaking. Participants share their medical histories, emotions, and frustrations in a structured yet open environment designed for intimacy, …


Dnp Final Report: Improving Adherence With Cms Sep-1 Sepsis Bundle In The Emergency Department, Emmanuel Bernards May 2025

Dnp Final Report: Improving Adherence With Cms Sep-1 Sepsis Bundle In The Emergency Department, Emmanuel Bernards

DNP Final Reports

Adherence to the CMS SEP-1 Sepsis bundles is critical to sepsis management and leads to lower sepsis mortality, lower incidence of readmission, reduced length of hospital stay, and improved patient outcomes. This medical center has struggled to meet the required 71% adherence rate set by the Center for Medicaid and Medicare, representing the benchmark of acceptable care of sepsis patients. Therefore, the following PICOT question arises: among the hospitals’ ED physicians and nursing staff (P), how does a multimodal approach consisting of education, visual reminders, and audit and feedback (I) compared to a single approach (education) (C) affect adherence to …


Examining Loss Of Imprint In F1 Hybrid Female Mice Due To X Chromosome Epimutation And The Implications For Autism, Arianna H. Roach May 2025

Examining Loss Of Imprint In F1 Hybrid Female Mice Due To X Chromosome Epimutation And The Implications For Autism, Arianna H. Roach

Honors Scholar Theses

Sex biases are prevalent among various neurodevelopmental disorders, with males experiencing them at higher frequencies or severities than females. This male bias is poorly understood, and our lab aims to elucidate this mechanism using our model of transgenerational epigenetic inheritance. Our lab identified the cluster of genes Xlr3b/4b/4c on the X chromosome that are imprinted in the female brain. Preliminary studies suggest that Xlr3 acts as a mediator molecule in our model. Xlr3 knockdown male mice exhibited significant meiocyte loss that can be attributed to Meiotic Sex Chromosome Inactivation. Their female offspring also displayed loss of imprinting of Xlr3 and …


The Interaction Between Physical Activity And Fruit And Vegetable Intake On Body Composition, Om S. Ghetia May 2025

The Interaction Between Physical Activity And Fruit And Vegetable Intake On Body Composition, Om S. Ghetia

Honors Scholar Theses

Objective: Fruit and Vegetable (FV) intake and Physical Activity (PA) are important lifestyle factors associated with body composition. This study assessed the combined impact of meeting FV intake and PA recommendations on body composition measures including body mass index (BMI), percent body fat (PBF), and waist circumference (WC) in adults aged 20–64 years from diverse backgrounds.

Design: A cross-sectional study conducted in Northeastern Connecticut.

Methods: A total of 124 participants completed a one-week dietary and PA record followed by anthropometric assessments. Participants were categorized into groups based on FV intake (≥400 g/day vs. < 400 g/day) and PA levels (≥600 MET-minutes/week vs. < 600 MET-minutes/week). Independent t-tests and chi-square tests were used to compare dietary intake, PA levels, and body composition outcomes across groups.

Results: Participants meeting FV recommendations had significantly …


The Connection Between The Gut Microbiome And Joint Pain, Masooma Shamsi May 2025

The Connection Between The Gut Microbiome And Joint Pain, Masooma Shamsi

Honors Capstones

Background – Gut microbiome impacts joint pain in osteoarthritis. Studies show the relationship between abundance and diversity of gut microbiome and pain. The objective of this study is to summarize the evidence on the effect of gut microbiome on pain.

Methods – Literature search was conducted through PubMed and CINAHL databases. Search terms include gut microbiome + joint pain. Articles that had terms joint pain, gut dysbiosis, or inflammation from the gut were included. Articles included information regarding abundance and diversity of the gut microbiome.

Results – 5 selected articles show the relationship between diversity and abundance in the gut …


The Impact Of Mentorship On Burnout Among Novice Nurse Faculty, Lucas Gless May 2025

The Impact Of Mentorship On Burnout Among Novice Nurse Faculty, Lucas Gless

Doctor of Nursing Practice Projects

Burnout among novice nurse educators contributes to increased rates of faculty turnover and vacancies in nursing education. This is especially significant in rural settings. This quality improvement project aimed to determine the impact of mentorship on novice nurse educators’ perception of burnout at a rural community college in East Texas. Utilizing a mixed methods design, novice nurse educators with less than two years of academic nurse education experience were assigned experienced faculty mentors over an eight-week period. The Maslach Burnout Inventory-Educators Survey (MBI-ES) measured emotional exhaustion, depersonalization, and personal accomplishment, both before and after the intervention. Data analysis, using the …


Quality Improvement Project Prevention Of Perioperative Pressure Injury Utilizing Scott Triggers Education, Assessment, And Interventions, Lisette Miller May 2025

Quality Improvement Project Prevention Of Perioperative Pressure Injury Utilizing Scott Triggers Education, Assessment, And Interventions, Lisette Miller

Doctor of Nursing Practice Projects

Abstract

The quality improvement project was initiated to educate perioperative staff on the evidence-based practice of Scott Triggers to reduce perioperative hospital-acquired pressure injuries (HAPIs). The purpose of the project was to provide Scott Trigger’s education to perioperative nurses for the reduction of perioperative HAPIs utilizing Scott Trigger's risk assessment tool and recommended interventions. Using a quantitative quasi-experimental design, the project consisted of two separate three-month data collection sets, one set collected pre-educational intervention, and the second set collected post-educational intervention. The project proved the use of the Scott Triggers high-risk assessment tool and utilization of the recommended interventions to …


Quality Improvement Project Impact Of Multidisciplinary Patient Education On Heart Failure 30-Day Readmission Rate, Jeanne P. Williams May 2025

Quality Improvement Project Impact Of Multidisciplinary Patient Education On Heart Failure 30-Day Readmission Rate, Jeanne P. Williams

Doctor of Nursing Practice Projects

Patients diagnosed with heart failure are at an increased risk for readmission to the hospital within 30 days of discharge, and their care costs are projected to continue to increase. This Doctor of Nursing Practice (DNP) quality improvement (QI) project aimed to implement an evidence-based initiative to mitigate the increased heart failure 30-day readmission rate on a 30-bed medical-surgical telemetry unit in an acute care facility. Using the teach-back communication method, multidisciplinary patient education was implemented to prepare patients diagnosed with heart failure to manage their condition once discharged home. The theoretical and implementation frameworks used were Lewin’s Change Model, …


Entry-Level Physical Therapists’ Perceptions Of Initial Employment, Richard G. Hubler Jr. May 2025

Entry-Level Physical Therapists’ Perceptions Of Initial Employment, Richard G. Hubler Jr.

Seton Hall University Dissertations and Theses (ETDs)

As physical therapy (PT) grows as an autonomous profession within the ever-changing healthcare system of the United States, PT educators strive to provide students all the training that they require for a career in professional clinical practice. Although graduates of PT education programs receive a doctoral degree, their preparedness to succeed in their early career is unclear. The purpose of this qualitative research study is to investigate the perceptions of entry-level physical therapists (PTs) toward early professional practice and their initial employment choices. Entry-level PTs that have been employed full-time for one year or less were interviewed to gain an …


Second Language Acquisition For Adults, Sara Santos Costa May 2025

Second Language Acquisition For Adults, Sara Santos Costa

Seton Hall University Dissertations and Theses (ETDs)

The process of Second Language Acquisition (SLA) has been explored by several scholars, who start with fundamental questions such as: “Does second language acquisition work in the same way as first language acquisition?” “What are the differences in the processes each individual experiences?” “Is it possible to become fluent in a second language at an older age?” This paper aims to show some key research conducted on this topic and provide a clear understanding of the processes that second language learners face.

This paper will delve into three main approaches to SLA: Behaviorist Theory, Universal Grammar (UG) and Interactionist Theory. …


Parental Vaccine Hesitancy And The Decision To Vaccinate Children Against Covid-19, Jessica Mckee May 2025

Parental Vaccine Hesitancy And The Decision To Vaccinate Children Against Covid-19, Jessica Mckee

Walden Dissertations and Doctoral Studies

While there is a significant body of literature regarding vaccine hesitancy, there is a gap in the literature on its impact to parents’ decisions to vaccinate their children against a pandemic pathogen. The purpose of this study was to examine the relationship between parental vaccine hesitancy, measured using the health belief model (HBM) theoretical framework constructs of the Vaccine Hesitancy Scale (VHS; the degree to which an individual trusts in vaccine efficacy, safety, the reliability and trustworthiness of vaccine programs, community impact, perceived risks, and the importance of childhood vaccinations), and parents’ decision to vaccinate their children against COVID-19 with …


Executive Summary: Development Of An Evidence-Based Prevention Bundle To Reduce Falls On An Inpatient Psychiatric Detoxification Unit, Ramatu Dougrey Jalloh May 2025

Executive Summary: Development Of An Evidence-Based Prevention Bundle To Reduce Falls On An Inpatient Psychiatric Detoxification Unit, Ramatu Dougrey Jalloh

Walden Dissertations and Doctoral Studies

Following a 16% increase in patient falls from 2023 to 2024 in an inpatient psychiatric detoxification unit, a quality improvement education project was implemented to assess the impact of an evidence-based fall prevention bundle on fall rates and nursing compliance. Nurses received education through a PowerPoint presentation to enhance understanding and implementation of the bundle, which included Edmonson reassessments after high-risk medication administration, ISHAPED bedside shift handoffs, care plan updates, and SWIFT daily safety huddles. Posttests identified that the objective score of 80% knowledge for nurses was met. During the 10-week implementation, the goal was 100% compliance with all bundle …


Dexmedetomidine As An Adjunct To Local Anesthetics In Neuraxial Anesthesia: A Scoping Review, Meaghan Elrod, Jacob Flake, Sarah Eggers, Kieraney Coston, Dwayne Accardo Dnp, Crna, Faana May 2025

Dexmedetomidine As An Adjunct To Local Anesthetics In Neuraxial Anesthesia: A Scoping Review, Meaghan Elrod, Jacob Flake, Sarah Eggers, Kieraney Coston, Dwayne Accardo Dnp, Crna, Faana

Doctor of Nursing Practice Projects

Purpose/Background

Neuraxial anesthesia is key for pain management and comfort during surgery. While local anesthetics and opioids have notable side effects, Dexmedetomidine (DEX) offers a promising alternative. Early studies suggest DEX improves pain control, prolongs anesthesia duration, and reduces opioid-related side effects. This review explores the benefits of incorporating DEX into neuraxial anesthesia for better patient safety and comfort

Methods

This scoping literature review took place from August 2023 to April 2024, utilizing PubMed, CINAHL, Cochrane Library, and Google Scholar for sources. After reviewing over 2,000 abstracts, 25 articles met the inclusion criteria, with nine selected as most relevant. Four …


Survey Of Medical Student Attitudes Regarding Uterine Transplant For Cisgender And Transgender Women: An Observational Study, Brandon Kim, Deidre Hurse, Abram Brummett May 2025

Survey Of Medical Student Attitudes Regarding Uterine Transplant For Cisgender And Transgender Women: An Observational Study, Brandon Kim, Deidre Hurse, Abram Brummett

Conference Presentation Abstracts

Purpose: This study wishes to survey medical students’ attitudes regarding legality of, funding for, and conscientious objection to uterine transplant (UTx) in cisgender and transgender women. Methods: Medical students were invited to complete an online anonymous survey from March 18, 2024 to April 1, 2024. Baseline demographics collected, and four-point Likert scales were used on four pairs of questions to evaluate attitudes regarding UTx for cisgender and transgender women. Subject responses to paired questions were analyzed using Fisher’s Exact Test. Strength of correlation between the paired questions were analyzed with Spearman’s Correlation. Results: A total of 96 responses were collected …


Editorial–Special Issue On Application Of Cold Atmospheric Plasma In Human And Veterinary Disease, Katharina Stapelmann, Eloisa Sardella, Vandana Miller May 2025

Editorial–Special Issue On Application Of Cold Atmospheric Plasma In Human And Veterinary Disease, Katharina Stapelmann, Eloisa Sardella, Vandana Miller

Kimmel Cancer Center Papers, Presentations, and Grand Rounds

Plasma medicine is a rapidly evolving interdisciplinary field that combines plasma science and engineering, chemistry, biology, and medicine. This special issue focuses on various ways to apply cold atmospheric pressure plasma in translating plasma technology into clinical applications. Ongoing research on the redox-based mechanism of plasma action, the concept of 'plasma dose' and device control is critical for advancing plasma medicine. As these applications move toward the clinic, ensuring the reproducibility and quality control of plasma sources is essential. The articles in this issue present examples of both direct and indirect plasma applications, with indirect treatments describing cell exposure to …


Know Thyself: A History Of Ancient Neuroscience, Alex Delano May 2025

Know Thyself: A History Of Ancient Neuroscience, Alex Delano

Departmental Honors & Graduate Capstone Projects

Neuroscience is often described as one of the youngest bodies of science, but documented study of the brain begins as early as the Neolithic period. The ancient Mediterranean was a hub for science, mathematics, philosophy, and literature, all disciplines necessary for the study of the brain. Evidence of neurosurgical procedures like trepanation and craniotomy began in the Neolithic period and were practiced and improved upon throughout the ancient Mediterranean. The first detailed studies on brain anatomy were carried out in the 3rd century BCE in Greece which created a necessary structure for future scientists to build on. While many …


Acne On The Valve: A Case Of Cutibacterium Acnes Prosthetic Valve Endocarditis And Aortic Root Abscess, Aiden Van Loo, Mitchell Schwocho, Francisco Davila May 2025

Acne On The Valve: A Case Of Cutibacterium Acnes Prosthetic Valve Endocarditis And Aortic Root Abscess, Aiden Van Loo, Mitchell Schwocho, Francisco Davila

Conference Presentation Abstracts

Introduction Infective endocarditis (IE) is a serious infection of the endocardium and the cardiac valves. Its incidence is on the rise, and this has been attributed to the aging population, healthcare-associated infections, and the growing use of intracardiac devices and prosthetic valves. IE is typically caused by gram positive cocci; although other more fastidious organisms can present in a subacute fashion. One such organism that is now becoming identified is Cutibacterium Acnes. It is a gram-positive anaerobe, most commonly known for causing acne. Given its ubiquity as skin flora, it can enter the blood stream and cause systemic infections. Here …


A Case Of Futile Mechanical Thrombectomy In Chronic Thromboembolic Pulmonary Hypertension, Daivd Connolly, Michael Barnes May 2025

A Case Of Futile Mechanical Thrombectomy In Chronic Thromboembolic Pulmonary Hypertension, Daivd Connolly, Michael Barnes

Conference Presentation Abstracts

Introduction Percutaneous mechanical thrombectomy is a mainstay therapy in the management of high-risk acute pulmonary embolism (PE), as it reduces pulmonary artery pressure and improves right ventricular function. However, the role of percutaneous mechanical thrombectomy in the management of chronic PE or acute on chronic PE is unclear. Case Description We present the case of a 46-year-old male who presented to the emergency department with 4 days of worsening dyspnea and pleuritic chest pain. Past medical history is significant for class II obesity, prior transient ischemic attack, pulmonary hypertension with right-sided heart failure, and four admissions over the previous 10 …


Unmasking Lupus Through Myopericarditis, Athanasios Rempakos, Lark Steafo, Tawhida Khatoon May 2025

Unmasking Lupus Through Myopericarditis, Athanasios Rempakos, Lark Steafo, Tawhida Khatoon

Conference Presentation Abstracts

Systemic lupus erythematosus (SLE) is a complex, multisystem autoimmune that often presents with nonspecific symptoms, complicating diagnosis. Myopericarditis is a rare initial manifestation, mimicking infections or malignancies. We present a case underscoring the importance of considering SLE in refractory multisystem illness. A 26-year-old previously healthy male presented to an outside hospital with a one-week history of left-sided pleuritic chest pain, fever, chills, palpitations, fatigue, cough, sinus congestion, and headache. Initial evaluation revealed marked tachycardia (heart rate 180s/min on exertion). CT pulmonary angiography excluded pulmonary embolism but identified a large right-sided consolidation consistent with pneumonia. His initial troponin was 223 with …


Stroke With Pfo, Uncovering Underlying Mutations And Malignancy: A Case Report, Haiqi Guo, Karan Chhabra, Atulya Khosla, Florian Bukovec, Dilip Khanal May 2025

Stroke With Pfo, Uncovering Underlying Mutations And Malignancy: A Case Report, Haiqi Guo, Karan Chhabra, Atulya Khosla, Florian Bukovec, Dilip Khanal

Conference Presentation Abstracts

Introduction: Stroke is the leading cause of long-term disability, with most cases being ischemic. In patients aged 18–60 years, patent foramen ovale (PFO) is implicated in 10% of strokes. Pathophysiologies include paradoxical thromboembolism and thrombus formation in the PFO, leading to cerebral or systemic embolism. Cancer is a comorbidity in 5–10% of patients with acute stroke, with mechanisms such as direct tumor effects, coagulopathy, and cancer therapy. Two common inherited thrombophilia predisposing to deep vein thrombosis (DVT) are Factor V Leiden (FVL) and G20210A Prothrombin gene mutation (PTM). FVL results in poor anticoagulant response to activated Protein C, while PTM …


Not A Cyst, But Gist: A Case Report, Jessica Kopchia, Amira Al-Nabolsi, Barbara Senger, Gurveer Gill, Yevhen Drobot May 2025

Not A Cyst, But Gist: A Case Report, Jessica Kopchia, Amira Al-Nabolsi, Barbara Senger, Gurveer Gill, Yevhen Drobot

Conference Presentation Abstracts

Gastrointestinal Stromal Tumors (GISTs) are the most common mesenchymal neoplasms found in the gastrointestinal (GI) tract, although they only account for 1-2% of gastrointestinal tumors. It is suspected that GISTs originate from the Cajal cells, necessary for regulating peristalsis. Diagnosis relies heavily on histopathologic examination, majority of GISTs being caused by an oncogenic mutation in the KIT gene, responsible for the regulation of tyrosine kinase. KIT upregulates the interstitial cells of Cajal, resulting in tumor formation. Therefore, these tumors are predominantly found in the stomach and small intestine, less frequently in colon, esophagus, and rectum. Often these neoplasms are benign, …