Medicine and Health Sciences Commons^™

Impact Of Transcatheter Aortic Valve Implantation (Tavi) On Left Ventricular Mass, Volumes, And Pressure. A Single-Center Echocardiographic Analysis, Fouad Taiwilaa Alshammari, Afrah Asaad Alonazi, Mohammed Dhaifallah Almutairi, Khaled Ahmed Majrashi, Atheer Mansour Almutairi, Muhammad Azam Shah

Journal of the Saudi Heart Association

Background: Transcatheter aortic valve implantation (TAVI) is an alternative treatment for surgically high-risk patients with severe aortic stenosis (AS). This study aimed to assess the echocardiographic outcomes of TAVI in patients with severe AS, focusing on left ventricular mass, volume, and pressure.

Methods: This retrospective,registry-based, single-center study was conducted at King Salman Heart Center, Riyadh, Saudi Arabia. We included 200 adult patients who underwent the TAVI procedure and completed at least one year of clinical and echocardiographic follow-up. Baseline demographic, clinical, and echocardiographic data were collected and paired pre- and post-procedure echocardiographic measurements were analyzed.

Result: Paired analysis …

Can The Location Of Angina Predict The Site Of Coronary Artery Occlusion In Acute Myocardial Infarction? – The Acolyte Study, Kamal Sharma, Ashwati Konat, Poojan Prajapati, Kavya Darji, Shalin Rawal, Vatsa Bhavsar, Prahar Darji, Yashrajsinh Gohil, Masum Patel, Shubham Patel, Parjanya Bhatt, Yashvi Pethani, Stuti Shah, Hardik Desai

Journal of the Saudi Heart Association

Aim: To evaluate the relationship between the location of chest pain (topography) and the site of coronary artery involvement in patients with acute coronary syndrome (ACS) undergoing percutaneous transluminal coronary angioplasty (PTCA).

Materials and Methods: This prospective, observational study included 411 consecutive ACS patients admitted to a tertiary care center between January 2017 and December 2019. A total of 589 angina topographic sites were analyzed. The site and characteristics of chest pain, along with electrocardiogram and coronary angiography findings, were documented and assessed for correlation with the involved coronary artery.

Results: Among the 411 patients, 337 (82.0%) were male and …

Effect Of Cardiac Rehabilitation Program On Left Ventricular Systolic Function In Patients With Breast Cancer Receiving Anthracycline-Based Chemotherapy Using Two-Dimensional Speckle Tracking Echocardiography, Sarah Mohamed Abdelhady, Ahmed Kadry Araquib, Adel Mohamed Shabana, Adel Gamal Hassanein, Ramy Raymond Elias

Journal of the Saudi Heart Association

Objectives: Anthracyclines used in the treatment of breast cancer are known for their cumulative cardiotoxic effect. Two-dimensional speckle tracking echocardiography is a promising technique in detection of subclinical cardiotoxicity. Cardio-oncology rehabilitation is a new field aiming to decrease the risk of cardiovascular diseases and improve cardiopulmonary fitness among cancer patients

Methods: The study included 100 female patients with de novo breast cancer and treated with anthracycline-based chemotherapy. Patients were randomly assigned into two groups in a 1:1 ratio. Group (1) included patients who were allocated to cardiac rehabilitation program in addition to their regular chemotherapeutic drugs and group 2 …

Artificial Intelligence-Enhanced Ecg For Hypertrophic Cardiomyopathy Diagnosis: A Systematic Review And Meta-Analysis, Fernando (Alonzo) Theja, Louis (Fabio Jonathan) Jusni, Robby Soetedjo, Dimetrio (Alonzo) Theja

Journal of the Saudi Heart Association

Objectives: Diagnosing hypertrophic cardiomyopathy (HCM) can be challenging due to its nonspecific clinical manifestations, variability in electrocardiographic (ECG) patterns, and limited access to echocardiography, the gold standard for diagnosis, often leading to delayed detection. Recent artificial intelligence (AI) advancements have enabled ECG-based algorithms to improve HCM detection. This systematic review and meta-analysis aim to assess the overall diagnostic performance of AI-enhanced ECG in identifying HCM.

Methods: This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Articles were retrieved from PubMed, EBSCO, and Proquest. Inclusion criteria encompassed all studies evaluating AI algorithms for the detection of …

Promoting Parent-Child Connectedness: Insights From A Parent Education Training, Bisola E. Duyile, Robyn Becker, Kate Papas, Shanta Pamphile

Journal of Interprofessional Practice and Collaboration

Purpose: This study explores the interrelationship of speech, language, and literacy development, parent-child connectedness, and children’s mental health when viewed as social determinants of health, specifically among families of children with developmental disabilities. Through interprofessional collaboration, researchers aim to identify effective strategies that parents can use to enhance their children’s communication skills and emotional well-being.

Methods: A mixed methods design was employed, involving a post-workshop survey completed by five mothers. The quantitative component included Likert scale items to measure satisfaction with social support. We also evaluated satisfaction with the workshop. The qualitative component comprised open-ended questions about newly learned tools …

Impact Of Interprofessional Instructional Design On Graduate Healthcare Students Collaborative Practice Competency, Karene Boos, Barbra Beck, Jamie Krzykowski, April M. Doebert-Fischer

Journal of Interprofessional Practice and Collaboration

Purpose This study examines the impact of three delivery models of an interprofessional education (IPE) curriculum on perceptions of interprofessional collaborative practice competencies among graduate-level health profession students. The curriculum was rooted in the Interprofessional Education Collaborative (IPEC) Core Competencies (2016).

Problem Statement Despite widespread recognition of the importance of IPE in preparing healthcare students for collaborative training by numerous health organizations, health profession programs, and their accrediting agencies, there is no clear pedagogical best practice for training students from various health professions to achieve effective interprofessional training.

Significance IPE is essential for fostering skills in interprofessional collaboration, a critical …

Enhancing Interprofessional Collaboration Among Rehabilitation Professionals For Spinal Cord Injury Care In Pakistan, Shala Cunningham, Martina Lukin, Neelum Zehra, Rachael Lowe, Abdulgafoor Bachani

Journal of Interprofessional Practice and Collaboration

Purpose

The purpose of this study was to explore the effectiveness of a course series for the rehabilitation of patients with spinal cord injury (SCI) on participants’ perceptions of interprofessional collaboration and teamwork.

Problem

In Pakistan, the prevalence of SCI has surged, highlighting the need for coordinated rehabilitation services. However, individuals with SCI in Pakistan often receive little to no rehabilitation after their injury, which negatively impacts their recovery outcomes. Furthermore, the understanding of collaborative education and practice appears to be limited within health organizations in Pakistan.

Significance

This study highlights the effectiveness of an interdisciplinary education program in improving …

An Innovative Constraint-Induced Movement Therapy (Cimt) Program Design And Case Study To Address Upper Extremity Use And Spatial Inattention, Mark Blanchard, Ingrid A. Franc, Payton Nisby, Michelle Arceneaux, Kathleen Chapiesky, Genevieve Ducros, Austin Brannon

Journal of Interprofessional Practice and Collaboration

Introduction: Common consequences of stroke include decreased upper extremity function and spatial inattention, both of which cause difficulties in occupational performance in activities of daily living. Constraint-Induced Movement Therapy (CIMT) is an intervention that has been utilized to improve these consequences of stroke.

Methods: This single case study describes the design and results of a two-week modified CIMT (mCIMT) program that used an enhanced visual and auditory feedback system, the Flint Rehab FitMi device, to address both upper extremity function and left spatial inattention in one participant. Left spatial awareness was encouraged during mCIMT activities by striking targeted pucks placed …

Interprofessional Collaboration Between Primary Care And Occupational Therapy, Ellen Modlin, Phd, Otr/L, Bcp, Caps, Deana Shevit Goldin, Phd, Dnp, Arnp, Fnp-Bc

Journal of Interprofessional Practice and Collaboration

Purpose: This article explores the utilization of occupational therapy (OT) in interprofessional health care teams in adult populations. Primary care settings are typically the first point of contact for individuals seeking health care services; therefore, primary care practitioners (PCPs) are in a unique position to initiate collaboration with specialty clinicians to optimize the use of health care resources.

Method: Peer- reviewed literature from primary care and OT research was reviewed and summarized. The search focused on barriers and potential opportunities for collaboration between primary care and occupational therapy in adult populations.

Results: Occupational therapy (OT) is underutilized, as lack of …

The Role Of Social Media In Higher Education For Recruitment And Retention And The Implications For Nursing Programs, Cari Granier, Jamie Gravois

Journal of Interprofessional Practice and Collaboration

Abstract:

Purpose: This review article assesses findings related to social media use in regards to student recruitment and retention for higher education institutions (HEIs) including schools of nursing. This review outlines the need for building a social media presence, creating engaging content for target audiences, available platforms, and posting times and frequency. Methods: A literature review was conducted with keywords including the following terms in combination with “social media and” higher education marketing, higher education recruitment, university marketing, university recruitment, college marketing, and college recruitment. Results: College applicants rely on social media when making decisions about …

Promoting Student Engagement In Interprofessional Education To Advance Institution-Based Research, Curriculum Development, And Practice Interventions, Natalya Salganik, Nicole Trupiano, Vani Patterson, Rajesh Mangrulkar

Journal of Interprofessional Practice and Collaboration

Promoting Student Engagement in Interprofessional Education to Advance Institution-Based Research, Curriculum Development, and Practice Interventions

Abstract

Background

The Michigan Center for IPE (C-IPE) Student Advisory Committee (SAC) is a student-run committee that serves as a collaborative student community among health professional schools at our institution. Since its creation in 2018, SAC identified a need for students to take a lead in improving the interprofessional education (IPE) experience at the University of Michigan in collaboration with the C-IPE.

Methods

Together with the C-IPE, SAC focused on three tasks to achieve its goals: (1) increasing student engagement in IPE, (2) increasing transparency …

Enhancing Physical Therapy Practice Through Interprofessional Collaboration: Addressing Elderly Self-Neglect Via Pt And Behavioral Health Integration, Alexia Stamas, Feroze Sio, Jodi Thomasian, Kate Jansen, Margaret R. Klausing

Journal of Interprofessional Practice and Collaboration

Purpose: This article examines the role of interprofessional collaboration between Physical Therapy (PT) and Behavioral Health (BH) services in identifying and supporting elderly individuals at risk of self-neglect. Through a case study, we explore the benefits of integrating interprofessional collaboration and APS reporting processes into PT practice.

Problem: Self-neglect among older adults is a critical public health issue often overlooked in healthcare settings. PTs, as mandated reporters, frequently encounter patients exhibiting signs of self-neglect but may lack training in psychosocial and cognitive assessment skills necessary for effective intervention.

Significance: Interprofessional collaboration enables PTs to address both physical …

Do Repeating Interprofessional (Ip) Courses Stimulate To Increased Development Of Ip Competencies?, Anders Baerheim, Ingunn Johanne Ness, Reidun Lisbeth Skeide Kjome, Merethe Hustoft, Sissel Johansson Brenna, Ane Johannessen

Journal of Interprofessional Practice and Collaboration

The aim of this study was to elucidate whether acquired interprofessional (IP) competencies increased with repeated IP courses. Methods. We used a cross-sectional survey including students from four IP courses at two Norwegian higher educational institutions. One site had a 1-2 weeks on-campus training for their bachelor students at the start of each of the three academic years, whilst the other site arranged a workplace-based course for final year health and social care students from both educational institutions. Students from the first site complete all three on-campus courses and the workplace-based course before completion of their education, while students …

2025 May 20 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Characterization Of Immunogenicity Of Hiv Mrna Vaccine In Humanized Mice, Omoyeni Precious Adejare

Biotechnology Theses

Human Immunodeficiency Virus (HIV) remains a leading global cause of mortality. Despite decades of research, a definitive cure or an effective vaccine for HIV infection has yet to be discovered. The major target for HIV vaccine development is the envelope (Env) trimeric protein that is responsible for host cell attachment and fusion. This comprises gp120 and the transmembrane gp41. Gp140, a truncated form of gp160(full envelope trimer) lacks the transmembrane and cytoplasmic domains of gp41, closely mimics the native HIV envelope has been shown to enhance the induction of broadly neutralizing antibodies (BnAbs) when used as protein vaccine in previous …

Various Bone Disorders Affecting The Medically Underserved South Texas Region, Blake Martin, Manoj Peiris, Michael Sander

School of Medicine Publications

Bone disorders can have a devastating impact on an individual’s quality of life. The main objective of our study was to analyze various demographic disparities between various bone disorders in the demographically unique Rio Grande Valley region. We hypothesized that osteoporosis would be the most prevalent condition and that the demographics between the various conditions would vary depending on age, sex, BMI, and ethnicity but not on marital status. This was a retrospective chart review using the University of Texas Rio Grande Valley UTHealth electronic database from January 1, 2017, to January 1, 2024. Any relevant individuals seen at a …

From M. Chelonae To M. Immunogenum: A Rare Case Of Dual Nontuberculous Mycobacterial Infection, Ifeanyi Kingsley Uche, Nathalia Simonetti, Andrea Murina

School of Medicine Faculty Publications

No abstract provided.

Optimizing Warfarin Management In Cardiovascular Care, Tessa A. Martinez

Doctor of Nursing Practice Final Manuscripts

Background: Maintaining a therapeutic International Normalized Ratio (INR) is essential to reduce bleeding and thromboembolic risks in patients on warfarin therapy. In a rural outpatient cardiac clinic serving a predominantly underserved population, many patients face financial and access barriers that preclude the use of newer non-vitamin K antagonist oral anticoagulants (NOACs). Patients with atrial fibrillation (AF) or mechanical valve replacements who rely on warfarin require consistent monitoring and management, which can be challenging in settings with limited resources and staffing.

Purpose: The purpose of this evidence-based pilot project was to improve therapeutic INR outcomes through the implementation of a standardized …

Improving Access And Retention Of Medication-Assisted Treatment (Mat) For Minority Inmates In The California State Prison System: A Quality Improvement Initiative Using A Culturally Competent Approach, Douglas Seangmany

Doctor of Nursing Practice (DNP) Projects

Abstract

Background: The opioid crisis disproportionately affects minority populations in correctional settings, where limited access to Medication-Assisted Treatment (MAT) contributes to high overdose rates and healthcare costs. At a California prison, only 48% of individuals with Opioid Use Disorder (OUD) receive MAT. Local Problem: Limited MAT access and low provider cultural competence exacerbate health disparities among minority inmates. Methods: A culturally sensitive training intervention was implemented for healthcare providers at a California prison, guided by a review of ten evidence-based studies. Pre- and post-training surveys on a 5-point Likert scale assessed provider competency, defined as "Agree" or …

Utilization Of Flow Cytometry, Metabolomic Analyses And A Feline Infectious Peritonitis Case Study To Evaluate The Physiological Impact Of Polyprenyl Immunostimulant, Irene Lee, Amar Desai, Akshay Patil, Yan Xu, Kelley Pozza-Adams, Anthony J. Berdis

Chemistry Faculty Publications

Measles, hepatitis C, and COVID-19 are significant human diseases caused by RNA viruses. While vaccines exist to prevent infections, there are a small number of currently available therapeutic agents that can effectively treat these diseases after infection occurs. This study explores a new therapeutic strategy using a small molecule designated polyprenyl immunostimulant (PI) to increase innate immune responses and combat viral infections. Using a multi-disciplinary approach, this study quantifies the effects of PI in mice and THP-1 cells using flow cytometry to identify immune phenotypic markers and mass spectroscopy to monitor the metabolomic profiles of immune cells perturbed by PI …

Comorbidities, Therapy And Health System Factors Associated With Treatment Interruption Among Males With Tuberculosis In Nairobi County, Kenya, Lorraine Nkirote Mugambi-Nyaboga

Walden Dissertations and Doctoral Studies

While males are recognized as key drivers of tuberculosis (TB) transmission, the association between comorbidities (i.e., diabetes and malnutrition), adverse drug reactions (ADRs), and health system factors (i.e., frequency of drug refills) with TB treatment interruption, remains unclear. I aimed to determine the association between these factors and TB treatment interruption among males diagnosed with TB in Nairobi County, Kenya controlling for age, sub-county of residence, alcohol use, HIV co-infection, type of TB and presence of treatment supporter. Guided by WHO’s framework on adherence to long-term therapies, a quantitative, case-control study was conducted using secondary analysis of Kenya’s TB surveillance …

Staff Education Program On Smoking Cessation Strategies, Justina Ugorji

Walden Dissertations and Doctoral Studies

This doctoral project implemented a staff education program to enhance smoking cessation knowledge in a mental-health care setting. Despite the well-documented risks, smoking cessation efforts remain insufficient, often due to providers’ limited knowledge and confidence in delivering effective interventions. The practice-focused question for this project was: Will implementing a staff education program improve health care providers’ knowledge of smoking cessation strategies as compared pre- to posteducation? The purpose was to equip providers with evidence-based techniques to enhance patient smoking cessation. A comprehensive literature review using the Johns Hopkins evidence-based practice model was performed, and 20 relevant articles were identified supporting …

Staff Education To Improve Staff Knowledge Of Medication Adherence Strategies For Mood Disorders, Samnang Son Oeur

Walden Dissertations and Doctoral Studies

Executive Summary: Staff Education Project Staff Education to Improve Staff Knowledge of Medication Adherence Strategies for Mood Disorders by Samnang Oeur MS, University of California, San Francisco, 2019 BS, University of Massachusetts, Lowell, 2009 Executive Summary Submitted in Partial Fulfillment of the Requirements for the Degree of Doctor of Nursing Practice Walden University August 2025

Identification Of Surrogate Biomarkers For Mucopolysaccharidosis Type Iva, Yasuhiko Ago, Shaukat Khan, Kimberly Klipner, Allison Bradford, Shunji Tomatsu

Department of Pediatrics Faculty Papers

Mucopolysaccharidosis type IVA (MPS IVA, Morquio A syndrome) is a rare inherited disorder characterized by skeletal dysplasia due to deficient N-acetylgalactosamine-6-sulfate sulfatase activity, resulting in glycosaminoglycan (GAG) accumulation. Identifying accurate biomarkers reflecting clinical severity and therapeutic response remains challenging. This study evaluated potential surrogate biomarkers, including N-terminal pro-C-type natriuretic peptide (NT-proCNP), collagen types I and II, mono-sulfated keratan sulfate (KS), di-sulfated KS, and chondroitin-6-sulfate (C6S), in blood and urine samples from 60 patients ranging from 1 to 62 years of age. NT-proCNP levels were significantly elevated in patients of all ages and negatively correlated with growth impairment, especially after 8 …

The Effect Of Nonsteroidal Anti-Inflammatory Drugs On Union Rates Following Operative Repair Of Distal Radius Fractures, Michael Chang, Alexis Kasper, Juliet Chung, Justin Wright, Margaret Pennington, Asif M. Ilyas

Student Papers, Posters & Projects

Purpose

Methods

The Association Between Neighborhood Environment, Social Relations, And The Prevalence Of Irritable Bowel Syndrome, Negin Iranfar

Walden Dissertations and Doctoral Studies

Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction influenced by biological, psychological, and social factors. Stress and socioeconomic influences on IBS have been studied, however few studies have explored the impact of neighborhood and social environments across racial and ethnic groups and sex at birth. The biopsychosocial framework was used to examine whether built environment and social context contribute to IBS prevalence. A cross-sectional analysis of 80,874 participants from the All of Us Research Program was conducted to assess the associations between IBS and six neighborhood and social factors: safety, structure, cohesion, supportive relationships, social relationships, and perceived …

Antifreezing Hydrogels From Mechanisms, Strategies, To Applications, Jie Zheng, Dong Zhang, Hong Cheng, Yanxian Zhang

University Research

Antifreezing hydrogels have emerged as an innovative solution for maintaining functional performance and mechanical integrity in subzero environments, offering a robust alternative to traditional water-free antifreezing materials that often fail under wet and cold conditions. These water-rich hydrogels leverage their porous, crosslinked, polymeric networks, which serve as the structural basis for implementing two parallel strategies: the incorporation of antifreezing additives (peptides/proteins, salts, ionic liquids, and organics) and the meticulous engineering of polymer systems and network structures for manipulating the water–ice phase equilibrium to significantly enhance antifreezing properties. This review synthesizes recent findings to provide a fundamental overview of the important …

Systematic Review On The Treatment Of Emotional Abuse Victimization In Women By An Intimate Partner, Günnur Karakurt, Rhea D’Silva, Çerağ Oğuztüzün, Ankita Choudhary, Keming Gao, Shari Bolen

Faculty Scholarship

Purpose: Emotional partner abuse, often closely intertwined with physical assault, involves persistent emotional mistreatment by an intimate partner. Despite its significance, research specifically focusing on emotional IPV is limited. This study systematically reviews the effectiveness of treatments for women victimized by emotional abuse from an intimate partner. Methods: Following the guidelines outlined in the Cochrane Handbook for Systematic Reviews of Interventions, we identified four relevant studies published between 2010 and 2019 with interventions designed for survivors of IPV. Results: The total sample size of 857 was included in the current study (I² = 95%). Our systematic review revealed two …

Development And Feasibility Testing Of An Implementation Evaluation Tool: Recommendations From The Managing Epilepsy Well (Mew) Network Research Collaborative, Martha Sajatovic, Clara Adeniyi, Jessie Black

Faculty Scholarship

Aims: The Managing Epilepsy Well (MEW) Network has led the development, testing and scale-up of epilepsy self-management (ESM). The MEW Integrated Database (MEW DB) is a pooled repository of archival studies that facilitates aggregate analysis. This report describes an implementation evaluation tool for ESM adopters. Methods: Publicly available materials on program implementation, adoption and sustainability as well as readiness surveys used by the MEW Network were reviewed, as were content domains and format styles relevant to ESM implementation. Requirements for data Tiers included: 1) survey Tier should be short (≤6 items) and completed quickly (< 3 min), 2) question and response format should be consistent, 3) data elements are relevant to ESM adopters and 4) the tool should be applicable across ESM programs. Iterative review, discussion and item-ranking yielded a final set of 3 distinct data element Tiers. Results: Implementation data elements assess the characteristics of organization that may be a potential ESM adopter (Tier 1), organizational readiness to ESM implementation (Tier 2) and perceptions of ESM program effects or impact by adopters at the individual and program levels (Tier 3). There are 18 data elements, 6 elements in each Tier. Organizational characteristics reflect health disparities among people with epilepsy and common comorbidities. Implementation readiness barriers include motivational factors, training and resources. Implementation experience/outcomes include perceived ESM duration, credibility, impact, likability and effectiveness. Conclusions: A brief and practical implementation evaluation tool for ESM has potential value and important clinical and policy implications in advancing care for people with epilepsy.

Intersectional Analysis Of Vaccination Inequity Among Individuals With Disabilities In The United States During The Covid-19 Pandemic, Philip Ndoki, Heba M. Athar, David O. Anderson

Journal of Social, Behavioral, and Health Sciences

We investigated how disability status, types, sociodemographic indicators, and reasons for not receiving vaccinations influenced COVID-19 vaccination rates among individuals with disabilities in the United States. Despite efforts, vaccination disparities persisted, necessitating a nuanced understanding of the barriers to vaccination. Using intersectionality theory and the social determinants of health framework, we examined the impact of marginalized identities and structural inequalities. Key questions included the association between disability status and vaccination uptake, differences among disability types moderated by sociodemographic factors, and the interaction between disability status and reasons for not vaccinating. We used Household Pulse Survey data from the U.S. Census …