Medicine and Health Sciences Commons^™

Psoriasis Effects On Psychological And Daily Activities In Patients Attending To Outpatient Clinics In Aldiwaniyah Teaching Hospital, Saja Abbas Musa, Hassan Raji Jallab, Akeel Hamid Jabur

Al-Qadisiyah Medical Journal

Background: Psoriasis is a chronic immune-related skin disorder affecting 2–3% globally, linked to heart disease, joint issues, metabolic syndrome, and psychological disorders. It also impacts social life, mental health, and work productivity, with added challenges in Middle Eastern patients due to stigma and limited healthcare access. Aim: To assess the psychological and functional impact of psoriasis on patients attending Al-Diwaniyah Teaching Hospital. It focuses on anxiety, depression, social disengagement, and effects on daily activities like work, exercise, sleep, and hygiene. The study also explores the relationship between disease severity and impairment levels. Material and Methods: The study was conducted at …

Correlation Of Norepinephrine With Some Biochemical Parametric In Patients With Type 2 Diabetes Mellitus, Aqeel Abed Nour Hadi, Ferdous A. Jabir, Muhammad Abd-Alwahab

Al-Qadisiyah Medical Journal

Background: Type 2 diabetes is a chronic metabolic disorder characterized by high blood sugar levels (hyperglycemia) resulting from the body's reduced ability to produce or use insulin effectively. Insulin is a hormone that regulates blood sugar levels, and in type 2 diabetes, the body either does not produce enough insulin or becomes resistant to its effects. This causes a buildup of glucose in the bloodstream, which can eventually harm organs and tissues. This study was carried out on patients who attended the Diabetes and Endocrinology Specialist Center of Marjan City for Medical Education in Babil Province; all patients were diagnosed …

Lipase And Tcf7l2 Polymorphism As Indicators Of Pancreatic Dysfunction In Patients With Breast Cancer, Dhay Ihab Al-Jdooa, Ahmed Ghdhban Al-Ziaydi

Al-Qadisiyah Medical Journal

Background: Pancreatic dysfunction is widely acknowledged as a critical issue in individuals with breast cancer. These biomarkers like insulin, lipase, and amylase or polymorphisms such as TCF7L2 can be correlated in assessing breast cancer in conjunction with other medicine relations such as pancreatic health. Objective: The aim of this particular study is to assess the role of breast cancer in pancreatic dysfunction by assessing the aforementioned biomarkers and gene polymorphisms. Methods: Following ethical guidelines, a case-control study was conducted involving female patients diagnosed with breast cancer and other breast cancer-free women. Various combined diagnostic tests, including ROC curve analysis and …

Ophthalmic Complications In Thalassemia Patients Using Iron Chelating Therapy, Haider Aswad Layikh, Zainab Yousif Ismael, Dheya Nema Kadhum

Al-Qadisiyah Medical Journal

Background:\ Thalassemia's are a group of genetic diseases which are considered as the most common single gene disorder which are usually treated with repeated blood transfusions that may lead to iron accumulations in the body with multi organ complications. Objectives:\ The objectives of this study was to evaluate the most commonly observed ocular signs and complications of beta-thalassemia major, as well as to determine whether there are any significant ocular side effects of the iron chelators taken by many of these patients for the treatment of their condition. Materials & Methods:\ this cross sectional study evaluated the …

Detection Of Uropathogenic Multidrug-Resistant Escherichia Coli And Klebsiella Pneumoniae Isolates In Some Immunocompromised Patients., Alaa Abd Atia, Manal Mohammed Kadhim

Al-Qadisiyah Medical Journal

Background: Multidrug-resistant E. coli and K. pneumoniae isolates are the most common causes of acquired urinary tract infections (UTIs). Objective: Conclude the prevalence of multidrug-resistant E. coli and K. pneumoniae isolates in urine samples from immunocompromised patients with UTIs. Methods: A total of 543 urine samples were collected from patients with supposed UTIs. MacConkey, chromogenic agar, and blood culture were used to cultivate the samples. Disk diffusion on Mueller-Hinton agar was used to select cultures that were positive for testing for antibiotic susceptibility. Excel and SPSS software were used to gather and analyze the data. Results: Of …

Leading Healthcare Improvement: An Implementation Strategy, Kelley Arredondo, Anthony Ecker, Lindsay Vaclavik, Jacquelene Shahin, Ashley Thompson, Molly Horstman, David Ramsey, Kyler M Godwin

Faculty, Staff and Students Publications

Introduction: Healthcare professionals often implement quality improvement (QI) initiatives but lack training to implement and sustain QI initiatives. Leading Healthcare Improvement (LHI) is a course that combines principles from change management, team science, and leadership effectiveness into an implementation strategy to enable clinicians to lead sustainable change.

Methods: LHI is a 6-session, 4-month interactive training. Learners work on an active QI project throughout the course. A Wilcoxon signed-rank test was conducted to evaluate pre- and post-course changes in learners' self-reported confidence across five QI competencies.

Results: Veterans Healthcare Administration clinicians and fellows completed the LHI pre- (n = 111) and …

Extended-Phase Anticoagulation For Pediatric Venous Thromboembolism After Einstein Jr, Nathan Wilken, Jun Teruya

Faculty, Staff and Students Publications

No abstract provided.

Fgfr3::Tacc3 Fusion And Notch1 Loss-Of-Function In A Case Of Hpv-Associated Sinonasal Squamous Cell Carcinoma: Diagnostic Challenge And Implications For Targeted Therapy, Xu Cao, Hong Yu, Reham Hamdy Abdulazim Soliman, Pei Ying, Songlin Zhang, Li Liang

Faculty, Staff and Students Publications

Sinonasal squamous cell carcinoma (SNSCC) comprises a heterogeneous group of tumors with emerging molecular subtypes. Human papillomavirus (HPV)-associated SNSCC is a distinct entity, although actionable genomic alterations beyond HPV-driven pathways remain underexplored. Distinguishing HPV-associated SNSCC from carcinoma ex inverted papilloma can be particularly challenging in limited biopsy specimens, as these lesions may appear morphologically similar. We report a case of HPV-associated SNSCC with concurrent FGFR3::TACC3 fusion and NOTCH1 p.C1416 stop-gain mutation.

Oncocytic Intraductal Carcinoma Of The Parotid Gland With Strn::Alk Fusion, Reham H Soliman, Chris Shi, Kevin E Fisher, Hong Yu, Fouad El-Dana, Xu Cao, Li Liang, Pei Ying, Songlin Zhang

Faculty, Staff and Students Publications

Intraductal carcinoma (IDC) of the salivary gland is an uncommon epithelial neoplasm characterized by a predominantly intraductal or intracystic proliferation rimmed by a myoepithelial cell layer. Advances in molecular profiling have revealed recurrent gene fusions in IDC, most frequently involving RET, although fusions implicating other kinase genes have also been described. Among these, ALK rearrangements are rare and remain poorly characterized. Herein, we report a case of oncocytic IDC of the parotid gland harboring a STRN::ALK fusion, further expanding the molecular landscape of this tumor. Although this fusion has been previously reported in intercalated duct IDC, to our knowledge, this …

Effect Of Androgen Receptor Polymorphism On Hypogonadism Severity And Efficacy Of Testosterone Replacement Therapy, Nelson W Mills, Beatriz S Hernandez, Peyton J Coady, Arnaav Walia, Gal Saffati, Daniela Orozco Rendon, Dalia Khera, Nadia Khera, Weitao Song, Mohit Khera

Faculty, Staff and Students Publications

Background: The preferred treatment for hypogonadism, testosterone replacement therapy (TRT), has a varying efficacy that is currently not fully understood. This observation may be explained by polymorphism of the androgen receptor (AR), a ligand-binding transcription factor whose polyglutamine tract length affects various health conditions and androgen sensitivity. It has been theorized that this polymorphism may also affect the severity of hypogonadism. This study sought to determine a correlation between hypogonadism severity, TRT efficacy, and number of CAG trinucleotide repeats in the AR gene.

Methods: One hundred sixty-two males presenting to a single institution with symptoms of hypogonadism were recruited for …

Limited Predictive Value Of Vaginal Discharge And Cervical Ectropion For Chlamydia Trachomatis Infection Detected By Direct Immunofluorescence, Dian Novitasari, Willy Sandhika, Ashon Sa'adi, Lusiani Tjandra

Folia Medica Indonesiana

Chlamydia trachomatis is one of the most common sexually transmitted infections, often asymptomatic, yet a major cause of infertility. In clinical practice, vaginal discharge and cervical ectropion are frequently used as syndromic indicators. However, their predictive value for Chlamydia trachomatis infection remains limited, particularly in regions with restricted access to NAAT/PCR, such as Indonesia. This study aimed to evaluate the diagnostic value of vaginal discharge and cervical ectropion as predictors of Chlamydia trachomatis infection using the Direct Immunofluorescence (DIF) method. This study used a cross-sectional design conducted among 93 reproductive-aged women from coastal areas of Jember, East Java, Indonesia, who …

Patterns Recognized In Ayres Sensory Integration®: A Scoping Review, Marica Botha, Janine Van Der Linde, Zoe Mailloux

Department of Occupational Therapy Faculty Papers

Background/Objectives: Associations between scores on tests of sensory integration functions demonstrated in numerous studies over six decades have contributed to the development of Ayres Sensory Integration® (ASI) theory and practice. Understanding these "patterns" aids therapists in their interpretation of assessment results, ensuring appropriate and effective intervention. This study aimed to describe and discuss published research on identified patterns related to constructs in the Ayres Sensory Integration® approach. Methods: Arksey and O'Malley's framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews Checklist were used. The literature review search was guided by the following …

Comprehensive Prediction Analysis Of Novel Noncoding Regulatory Variants Identified In The Microrna Binding Regions In Complement System Genes, Anthony Shadid, Haydn E Rich, Kathryn D Hok, Marie-Francoise Doursout, Marcos I Restrepo, Nirmal K Banda, Lavanya Gunamalai, Pooja Shivshankar

The Brown Foundation: Institute of Molecular Medicine

The complement system is a central component of innate immunity that coordinates host defense, immune surveillance, and inflammatory responses through tightly regulated proteolytic cascades. Genetic variation within complement genes contributes substantially to interindividual differences in complement activity and disease susceptibility. While coding variants directly alter complement protein structure and function, the microRNA (miRNA)-mediated control and post-transcriptional regulation is not fully understood in shaping complement gene expression across immune and inflammatory mechanisms. Complement pathway genes exhibit extensive and heterogeneous 3'-untranslated regions (3'UTRs), which serve as primary platforms for miRNA binding and RNA-binding protein interactions. Both common and rare single-nucleotide polymorphisms within …

Analysis Of Priority Vaccine-Preventable Diseases Using The Paho-Adapted Hanlon Method In Bogor City In 2024, Sonia Annisa Br Ketaren, Tri Yunis Miko Wahyono, Bai Kusnadi

Jurnal Epidemiologi Kesehatan Indonesia

Vaccine-preventable diseases (VPDs) remain a major public health challenge despite substantial progress in immunization programs. In Indonesia, routine immunization coverage has shown a post-pandemic recovery trend; however, disparities in access to health services and surveillance quality persist across regions. This study aimed to determine priority VPD problems in Bogor City and identify factors contributing to the highest-ranked disease. A mixed-methods study was conducted in Bogor City from October 2024 to January 2025. Quantitative prioritization was performed using the Pan American Health Organization (PAHO)-adapted Hanlon method across eight VPDs. Qualitative data were collected through in-depth interviews with key informants and analyzed …

Patterns And Determinants Of Measles Among Suspected Cases In Jakarta: Insight From Surveillance Data 2022-2024, Widya Inayah, Nurhayati Adnan Prihartono, Retno Henderiawati, Oktaviana Nugraheni, Dwi Gayatri

Jurnal Epidemiologi Kesehatan Indonesia

Measles remains a public health concern in Indonesia, including Jakarta, contributing to the country’s disease burden. Sustained transmission during 2022-2024, despite reported vaccination coverage above  90%, suggests the presence of vulnerable groups. This study aimed to describe patterns and identify factors associated with laboratory-confirmed measles in Jakarta during 2022-2024. A cross-sectional study was conducted using routine surveillance data from all individuals reported as suspected measles cases during the study period. Descriptive analysis summarizes the distribution, while multivariable analysis identifies associated factors. Of the 4,194 suspected cases of measles, 22.8% were laboratory-confirmed positive. Showed a fluctuating temporal pattern, increasing from 20.6 …

Activities Of Daily Living Limitations In Middle-Aged And Older Adults With Joint Disorders And Osteoporosis: Indonesia Longitudinal Aging Survey 2023, Desfalina Aryani, Mufti As Siddiq As Siddiq M. Irzal, Agustina Sianipar

Jurnal Epidemiologi Kesehatan Indonesia

Population ageing is associated with an increasing prevalence of limitations in activities of daily living. Joint disorders and osteoporosis are common health problems among older adults and may begin to emerge during middle age, potentially accelerating functional decline. However, studies examining the association between these conditions and limitations in activities of daily living in Indonesia remain limited. This study aimed to analyse the association between joint disorders and osteoporosis and limitations in activities of daily living among middle-aged and older adults in Indonesia. This study employed a cross-sectional design using data from the Indonesia Longitudinal Aging Survey (ILAS) 2023. The …

Determinants Of Hypertension Status Among Patients With Type 2 Diabetes Mellitus At Menteng Primary Health Center, 2024–2025, Ira Susanti Haryoso, Yudha Radityadana, Muthik Hanim Mufallahah, Lhuri Dwianti Rahmartani

Jurnal Epidemiologi Kesehatan Indonesia

Hypertension is a common comorbidity in patients with type 2 diabetes mellitus (T2DM) and substantially increases the risk of both macrovascular and microvascular complications. Data on the determinants of hypertension status among T2DM patients in primary healthcare settings remain limited. This study aimed to analyze the determinants of hypertension status in T2DM patients at Puskesmas Menteng during 2024–2025. This was an analytic observational study employing a cross-sectional design. Study subjects comprised T2DM patients registered and undergoing examinations at Puskesmas Menteng over the 2024– 2025 period. Data were extracted from electronic medical records, included age, sex, occupation, socioeconomic status, blood pressure, …

Association Of Household Economic Status And Birth Order With Stunting Among Children Aged 24-35 Months: Malawi Mics 2019–20, Sibongire B. Ngoma, Asri C. Adisasmita, Renti Mahkota, Septyana Choirunisa, Melisa Nyamukondiwa

Jurnal Epidemiologi Kesehatan Indonesia

Stunting remains a major public health concern in Malawi, with a national prevalence of 35.5% among children under five. However, evidence on the independent and combined effects of household economic status and birth order on stunting among Malawian children aged 24-35 months remains limited. This study aimed to examine the independent and combined association of household economic status and birth order with stunting among children aged 24-35 months in Malawi. A secondary data analysis of a cross-sectional 2019-20 Malawi Multiple Indicator Cluster Survey (MICS) was conducted, and the final sample comprised 2,764 children aged 24-35 months with complete data. Stunting …

Clinical Epidemiology Of Stroke In The Productive Age Population In Indonesia: A Scoping Review, Satria Akbar Putra Asmara, Ulil Albab Habibah

Jurnal Epidemiologi Kesehatan Indonesia

Data from the 2018 Indonesian Basic Health Research (Riskesdas) demonstrates a marked increase in stroke prevalence, rising from 7% in 2013 to 10% in 2018. This upward trend is accompanied by a notable epidemiological shift, with stroke no longer predominantly affecting older adults ≥65 years, but increasingly occurring among the productive-age population (15–64 years). This scoping review was conducted in February 2026 in accordance with the JBI methodological guidelines and PRISMA-ScR. Searches were conducted in Google Scholar, PubMed, Garuda, and ScienceDirect. Inclusion criteria include articles published within the last 10 years (2016–2026), articles discussing the characteristics of stroke patients in …

Liver Function Test (Lfts) Revealed Ameliorative Effect Of Probiotics And Antibiotics As Therapeutic Agents Against Experimentally Induced Enterotoxemia In Goat, Muhammad Mohsen, Jam Kashif Zaman, Amjad Hussain Mirani, Nazeer Hussain Kalhoro, Benazir Sahito

Journal of Bioresource Management

Present study was conducted to evaluate the various liver enzymes in experimentally induced enterotoxemic goat inorder to ensure the therapeutic potential of probiotics and antibiotics. Experiment was conducted at Department of Veterinary Medicine, Sindh Agriculture University Tandojam in which 35 non-descriptive goats were housed and experimenatally induced with enterotoxemia by inoculation of Clostridium perfringens culture surgically by performing laparotomy into intestine. After apperence of positive clinical signs of infection, goats were randomly divided into 5 treatment groups i.e. Group 1 (negative control), Group 2 (positive control), Group 3 (yogurt, 5 % solution, 50 mL/time), Group 4 (Yeast, 5 % solution, …

Faktor Yang Berhubungan Dengan Lama Rawat Inap Pasien Demam Berdarah Dengue Di Rumah Sakit Islam Nahdlatul Ulama Demak, Akhmad Safi’I, Solikhatur Rohmah, Muhammad Zulfikar Asumta, Abdul Aziz, Masruroh Hasyim, Zulfa Khusniyah, Mukhamad Rajin

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Dengue Hemorrhagic Fever (DHF) is an acute infectious disease that often requires hospitalization with a variable length of stay (LOS). Several factors have been shown to influence LOS; however, findings from previous studies conducted in different hospitals remain inconsistent. This study aimed to analyze the association between age, gender, platelet count, hematocrit level, and leukocyte count with LOS among patients with DHF at Nahdlatul Ulama Islamic Hospital (RSI NU) Demak. This study employed a cross-sectional design using medical record data from 64 hospitalized patients with DHF admitted between January and May 2025, selected through purposive sampling. The sample eligibility criteria …

Male Allyship: What Utahns Need To Know, Susan R. Madsen, Deborah Lin

Marketing and Strategy Faculty Publications

Women do not always have the same opportunities as men, particularly in cultures where more traditional gender norms are embraced. Male allyship can positively impact women’s lives by increasing opportunities (e.g., safety, education attainment, career development, financial security). In addition, understanding and embracing gender differences can optimize women’s participation and leadership contributions. By intentionally removing barriers and encouraging full participation, women’s talents and perspectives can be leveraged. This both expands opportunities for women and enhances innovation, improves decision-making, and contributes to stronger communities.

Modeling Framework To Demonstrate Elimination Of A Vector Population: Tsetse Elimination In Chad, John Hargrove, Mahamat Hissene Mahamat, Moukhtar Aldjibert, Wilfrid Yoni, Djoukzoumka Signaboubo, Justin Darnas, Ernest Salou, Inaki Tirados, Albert Mugenyi, Priscille Barreaux, Philippe Solano, Antoine Marc Gaby Barreaux

All Peer-Reviewed Publications

Every year, over 700,000 people, particularly children under five, die from vector-borne diseases worldwide. Effectively controlling endemics and preventing new outbreaks requires an integrated approach that can lead to the elimination of both vectors and diseases. In the last two decades, integrating medical interventions and vector control has significantly reduced the incidence of Gambian Human African Trypanosomiasis (g-HAT), with the World Health Organization validating eight countries as having eliminated the disease as a public health problem. However, elimination of the tsetse vector has not been confirmed, leaving the possibility of re-emergence. We developed a six-step modeling framework to assess vector …

Clinical And Hematological Correlates Of Common Viral Respiratory Infections In Patients With Acute Illness In Iraq, Israa Habeeb Naser

Journal of Bioresource Management

Background: Acute viral respiratory infections are considered as the leading causes of illness and hospitalization worldwide. Influenza virus, Respiratory Syncytial Virus (RSV) and Adenovirus are general respiratory pathogens linked with significant clinical problems in Iraq. This study aims to estimate the prevalence of common respiratory viral infections and their clinical and hematological associations between Iraqi patients with acute-illness.

Methods: This a cross-sectional study was done on 160 patients showing acute febrile and/or respiratory-symptoms. Viral detection for Influenza virus, RSV and Adenovirus was performed using rapid-antigen and ELISA assays. Hematological tests including total leukocyte count (TLC), differential leukocyte count, hemoglobin and …

Endophytic Actinobacteria: Deciphering Therapeutic And Industrial Potential, And Prospects Of Genome Mining In Novel Products Discovery, Yusra Waheed, Rabia Shahdin, Imran Sajid

Journal of Bioresource Management

Endophytic actinobacteria are a diverse group of Gram-positive bacteria with high G+C content, which inhabit plants’ internal tissues, and represent a significant yet underexplored reservoir of bioactive secondary metabolites. In host plants, a remarkable repertoire of metabolites, including broad-spectrum antibiotics, anticancer, antiviral, antifungal, antioxidant, and immunomodulatory compounds, is synthesized by these microbial allies, carrying significant medicinal and agricultural potential. These endophytes, in contrast to their soil relatives, have developed unique biosynthetic gene clusters (BGCs) strongly influenced by plant-associated factors, leading to the production of structurally novel metabolites. In recent years, the advances in genome mining, metagenomics, and metabolomics have accelerated …

Prevalence And Risk Factors Association Of Babesiosis In Cattle And Buffaloes In District Naushahro Feroze, Sindh, Pakistan, Kazim Raza, Amjad Hussain, Sajid Moin, Huzaifa Arain, Muhammad Mohsen, Maria Abubakar, Erum Bughio, Barkat Ali

Journal of Bioresource Management

Background: Bovine babesiosis is a protozoan disease that is transmitted by ticks and has significant veterinary and economic impacts on tropical livestock systems. Prior to this study, no epidemiological data was available of Sindh, Pakistan.

Purpose: To estimate the Babesia spp. prevalence and estimate the risk factors with respect to cattle and buffaloes in five tehsils of District Naushahro Feroze, Sindh, Pakistan.

Methods: A cross-sectional study was conducted using 200 blood samples (100 Thari cattle; 100 Kundhi buffaloes; both sexes) in five tehsils (Kandiaro, Moro, Mehrabpur, Bhiria and Naushahro Feroze). Thin blood smears under Giemsa stain were viewed under oil-immersion …

Comments On The Letter – Intraoperative Tissue Oxygenation And Postoperative Creatinine Rise: Interpreting The Microcirculatory Context, Bhakti Banerjee, Haripada Das, Lini Srivastava, Snigdha Pramanik, Diptimay Majumder

Journal of the Saudi Heart Association

No abstract for this article type.

Intraoperative Tissue Oxygenation And Postoperative Creatinine Rise: Interpreting The Microcirculatory Context, Bedirhan Buğra Bayıcı,, Fatih Kızılyel

Journal of the Saudi Heart Association

No Abstract for this article type

Serial Radiographic And Ultrasonographic Evaluation Of Discospondylitis In A Cat: A Case Report Of Progressive Vertebral Lysis Despite Clinical Improvement, Geunah Kim, Jungho Lee, Seulgi Bae, Sang-Kwon Lee, Kija Lee

The Thai Journal of Veterinary Medicine

A 10-year-old castrated male Korean Shorthair cat was presented with a 5-day history of lethargy and nonambulatory paraparesis. Neurological examination revealed delayed postural reactions in both pelvic limbs. Initial radiography of the lumbar spine revealed narrowing of the L7–S1 intervertebral disc space with ventral bony proliferation. Magnetic resonance imaging revealed collapse of the L7–S1 intervertebral disc space with heterogeneous T2-weighted hyperintensity and ventral contrast enhancement of the affected disc, as well as contrast enhancement of the adjacent paraspinal musculature. These findings suggested the presence of discospondylitis. Coccoid bacteria detected in both urine and splenic fine-needle aspirate indicated hematogenous spread. The …

Microelement Deficiencies In Perimenopausal Women And Their Impact On Metabolic And Physical Performance: Potential Applications Of Vis–Nir Tissue Spectrophotometry And The So/Check Platform, Izabela Pabin, Damian M. Dudek, Łukasz Jaworski, Ewa Maria Kłodzińska

Baltic Journal of Health and Physical Activity

Background: The perimenopausal period, typically occurring between the ages of 40 and 55 years, represents a critical transitional stage in women’s physiology characterized by profound hormonal, metabolic, and systemic adaptations. While the endocrine aspects of this transition have been extensively investigated, increasing attention has recently been directed toward the role of micronutrient homeostasis in maintaining metabolic health and physical performance during this period. Therefore, the aim of this narrative review is to summarize current knowledge regarding microelement deficiencies in perimenopausal women and their potential impact on metabolic health and physical performance. Additionally, the review discusses the potential applications of VIS–NIR …