Medicine and Health Sciences Commons^™

The Epidemiology Of Sports And Recreation Related Toe Fractures In The United States, Dogerno Norceide, Gabriel I. Onor, Oluwatomi Akingbola, William Justice, Nana F. Amponsah, Abimbola Okulaja, Ifeanyichukwu Onor, Michael Okoronkwo, Chibuikem Nwizu, David Pedowitz, Md

Rothman Institute Papers

BACKGROUND: Fractures of the toes are among the most frequently diagnosed lower extremity fractures. In sports, toe fractures may present after diverse mechanisms of injury, varying severity, and varying implications for management. This study aimed to discern trends in toe fractures presenting to US emergency departments (EDs) particularly in association with sports and recreational activities. An additional aim of the study was to identify if rates of toe fracture presentation significantly decreased during the year 2020 at the height of the COVID-19 pandemic.

METHODS: We queried the National Electronic Injury Surveillance System (NEISS) database to identify toe fractures presented to …

U.S. Young Adults’ Family-Building Intentions In The Event Of Infertility And Knowledge Of Associated Costs, Jean Marie Place, John Horowitz, Minh Nguyen, Maya Guinn, Brennan Peterson

Marriage and Family Therapy Faculty Articles and Research

Introduction: Infertility affects approximately 8.5% of married women in the United States, yet there is limited understanding of how young adults anticipate and prepare for potential barriers to biological parenthood. As reproductive planning increasingly intersects with social, medical, and financial considerations, it is important to examine how emerging adults perceive and approach family-building options. This study aims to explore college students' intentions regarding childbearing, their openness to non-traditional family-building methods, and their awareness of the associated financial costs.

Methods: A cross-sectional survey was administered to undergraduate students (mean age = 20) at a Midwestern public university. Most participants had not …

Incidence, Risk Factors And Clinical Outcomes Of Pericardial Effusion In Left Ventricular Assist Device Patients, Muhammad Zubair Khan, Yevgeniy Brailovsky, Mohammad Alfrad Nobel Bhuiyan, Gregary D. Marhefka, Abu S. M. Faisal, Adrija Sircar, Parker O'Neill, J. Eduardo Rame, Sona Franklin, Muhammad Waqas, Hadia Shah, Indranee Rajapreyar, René J. Alvarez

Division of Cardiology Faculty Papers

BACKGROUND: Development of pericardial effusion in patients with left ventricular assist devices (LVADs) can be detrimental to health outcomes. This study aims to elucidate the prevalence and risk factors for pericardial effusion in patients with LVADs.

AIM: To elucidate risk factors associated with the presence of pericardial effusion in patients with LVADs and compare the clinical outcomes of those with and without pericardial effusion. The secondary goal is to determine the incidence of pericardiocentesis and pericardial window placement in patients with LVADs experiencing pericardial effusion.

METHODS: Data were obtained from the National Inpatient Sample database between 2016 and 2018. Statistical …

Deliberately Queer Journal Editors' Note For Volume One, Sean Te Maulding, Mel Monier

Deliberately Queer Journal

No abstract provided.

Psoriasis Genomics: A Review, Magna Hutasuhut, Windy Keumala Budianti, Wresti Indriatmi, Mirawati Setyorini

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Psoriasis is a dermatological condition influenced by genetic and epigenetic factors, environmental triggers, as well as immune responses. Genomics refers to the study of individual genes (genomes) and their interactions with environmental influences. In the context of psoriasis genomics, the interplay between genetic predisposition and environmental factors contributes to the manifestation and variations of the disease. With advancements in molecular genotyping technology and genome-wide association studies (GWASs), researchers have identified 50 genetic markers linked to psoriasis.

Discussion: Several genetic loci associated with psoriasis have been identified, including PSORS 1-15. The genetics of psoriasis is also linked to its onset, …

Voclosporin‐Induced Gingival Enlargement: A Case Report, Dimitris N. Tatakis

Faculty Scholarship

The gingiva (gums) is often a site in the mouth where changes or reactions can occur in response to certain systemic medications. Some drugs, particularly those used to treat autoimmune conditions or following organ transplants, can cause the gums to grow excessively, a condition known as drug-induced gingival enlargement (also known as gingival overgrowth). In this report, we document the case of a 27-year-old woman with lupus nephritis who developed gingival enlargement after starting a medication called voclosporin. This drug is a newer treatment option for lupus nephritis, but until now had not been linked to gingival enlargement. The patient …

Retrocerebellar Arachnoid Cyst Treated By Individualised Homoeopathic Medicine Calcarea Phosphorica: A Case Report, Abhishek Soni, Syed Afsar Ali, Aiswarya Singha

Indian Journal of Research in Homoeopathy

Introduction: Arachnoid cysts are non-malignant malformations mainly relating to the arachnoid mater. Arachnoid cysts involving the posterior fossa are less common and are most often found in the cerebellopontine angle. Common presenting complaints include headache, visual disturbances, gait disturbances, and seizures.

Case Summary: This is a case of a 4-year-old male child with a retrocerebellar arachnoid cyst treated in the outpatient department of the National Institute of Homoeopathy, Kolkata, India. The presenting complaints included trembling of the whole body since one year, which was completely resolved within 18 months of individualised homoeopathic treatment. The case was thoroughly analysed and treated …

Homoeopathy In Integrative Management Of Reduced Left Ventricular Ejection Fraction: An Evidence-Based Case Report, Mehadi Arif Billah, Rajib Purkait, Gurudev Choubey, Pralay Sharma

Indian Journal of Research in Homoeopathy

Background: Left ventricular ejection fraction (LVEF) is the central measure of left ventricular systolic function. It is one of the most useful tools to evaluate cardiac diseases. Heart failure with a reduced ejection fraction affects more than 50% of individuals. This subject is inadequately documented in Homoeopathy. This case study intends to create evidence-based documentation and generate the hypothesis that Homoeopathy can treat these potentially fatal illnesses. Case Summary: A 33-year-old female presented with complaints of palpitation, dyspnoea on least exertion and pain in both upper and lower limbs with associated numbness extending downwards for three months. She had a …

Mixed Hearing Loss With Csom Managed With Individualised Homoeopathic Treatment: A Case Report, Prince Kumar

Indian Journal of Research in Homoeopathy

Introduction: Any stage of life might see the development of hearing loss (HL). One or both ears may be affected, and the onset may occur suddenly or gradually. Numerous factors, such as trauma, illness, genetic disorders, age, or prolonged exposure to noise, can cause HL. One or more auditory system areas may have pathological alterations as a result of the changes. The majority of adult HL is permanent or gradually progresses; however, some may be momentary or amenable to treatment with medication or surgery. Case Summary: A 17-year-old male adolescent was treated with homoeopathic medicine in an obstinate case of …

Usefulness Of Homoeopathic Medicine Lachesis Mutus In Treating Cervical Dystonia: A Case Report, Kamlesh P. Kakde, Vinaya Ganesan Iyer

Indian Journal of Research in Homoeopathy

Introduction: Cervical dystonia is a neurological disorder characterised by painful, involuntary muscular spasms affecting the neck and head. It is commonly of idiopathic origin and associated with a poor prognosis. Conventional management typically includes botulinum toxin administration or surgical interventions, which provide only partial relief and are often accompanied by symptom recurrence. Emerging evidence suggests that individualised homoeopathic treatment may offer superior efficacy in such cases. Case Summary: A 40-year-old male came to the clinic with pre-diagnosed condition of cervical dystonia for four years. Complete Repertory was utilised for remedy analysis and confirmation, which led to the prescription of …

Immunoglobulin E Modulatory Effect Of Individualised Homoeopathy In A Child Suffering From Immunological, Chronic Spontaneous Urticaria: A Case Report, Ranjit Sonny, Patranu Parui

Indian Journal of Research in Homoeopathy

Introduction: Urticaria is one of several immune-mediated diseases. It is very troublesome and hampers the quality of life significantly. Chronic spontaneous urticaria (CSU) is associated with red, oedematous, erythematous, raised and itchy wheals with or without angioedema. A serological marker such as immunoglobulin E (IgE) is raised in urticaria, which is one of the diagnostic criteria of urticaria. The successful treatment lies in the fact of controlling or immunomodulating the IgE level. As per available data, Homoeopathy is very effective for the management of urticaria by bringing down the serum IgE level within normal limits. Case Summary: A …

Role Of Bowel Nosode Bacillus Morgan In The Management Of Post-Infective Irritable Bowel Syndrome: An Evidence-Based Case Report, Priyagauri Ajey Chaphekar, Dharmendra Sharma

Indian Journal of Research in Homoeopathy

Background: Irritable bowel syndrome (IBS) is a functional disorder characterised by multifactorial causes and is classified according to Rome IV criteria into IBS-constipation, (IBS-diarrhoea prominently in post-infectious cases), and IBS-mixed symptoms. Psychological factors and certain foods fermentable oligosaccharides, disaccharides, monosaccharides, and polyols are known to aggravate the condition. The morbidity rate of IBS is a global concern as it negatively impacts the patient’s quality of life, leading to psychological distress, financial losses, and reduced work efficiency. Case Summary: This case report highlights a 69-year-old female patient who experienced a (acute) sudden onset of IBS symptoms, that is., an urgent need …

Therapeutic Response Of Homoeopathic Medicines In Management Of Nicotine Dependence And Withdrawal: A Case Series, Ralte Lalmuanpuia, Kathika Chattopadhyay, Ashwini Nair, Anuroopam Swami, Daisy Katarmal

Indian Journal of Research in Homoeopathy

Introduction: On discontinuing or decreasing nicotine use, nicotine-dependent individuals, often smokers, may experience withdrawal symptoms such as irritability, frustration, anxiety, depression, difficulty concentrating, restlessness and insomnia. These symptoms can significantly impact their quality of life, affecting physical health, psychological state, social relationships, personal beliefs and daily activities. The most commonly recommended conventional treatment for nicotine withdrawal is nicotine replacement therapy (NRT), which aims to reduce cravings and ease symptoms. However, NRT can be habit-forming and has been associated with a variety of adverse effects.

Cases Summary: We report four cases of nicotine dependence managed solely with homoeopathic interventions …

Primary Infertility In A Female Due To Ovarian Endometrioma Managed With Homoeopathic Medicine Pulsatilla – A Case Report, R. Bhuvaneswari, R.S. Thendral, Nilina P. Ravindran, Sakthivel Vaiyapuri

Indian Journal of Research in Homoeopathy

Background: Infertility is defined as the failure to achieve a natural pregnancy after 12 months of regular unprotected sexual intercourse. There are various factors influencing fertility in females, such as ovulatory disorders, endometriosis, pelvic adhesions, tubal blockage, other tubal/uterine abnormalities and hyperprolactinemia, among which endometriosis is the second most common cause of female infertility. Endometriomas are cystic lesions that stem from endometriosis. This case report explores the usefulness of individualised homoeopathic treatment in addressing primary infertility associated with ovarian endometrioma.

Case Summary: A 27-year-old woman with a history of laparoscopic cystectomy and three unsuccessful intrauterine insemination attempts sought …

Adjunctive Homoeopathic Treatment Of Covid-19-Positive Cases Of Geriatric Age Group – A Case Series, Vinitha Edavattath Ramanan, Suhana P. Azis, K.C. Muraleedharan, Divya Babu

Indian Journal of Research in Homoeopathy

Introduction: The second wave of COVID-19 peaked during May 2021 and had a higher mortality and morbidity rates than the first wave. About 53% of people over 60 years of age died in India due to the pandemic by the end of July 2021. Cases Summary: Twenty reverse transcription-polymerase chain reaction-confirmed COVID-19-positive patients belonging to the geriatric age group were successfully treated with Homoeopathy. Seventeen of these consulted through in-person visits at a long-term care facility (LTCF) for the elderly, and three cases belonged to the home-isolated category. Out of those treated, 14 had comorbidities, such as type II …

Benign Prostatic Hyperplasia Treated With Staphysagria In Lm Potency: An Evidence-Based Case Report, Karunakara Moorthi, K.R. Siva Tharshini

Indian Journal of Research in Homoeopathy

Introduction: Benign prostatic hyperplasia (BPH) is a non-cancerous condition characterised by the enlargement of the prostate gland in men. When the prostate enlarges, it can press against the urethra and cause various urinary symptoms.

Case Summary: A 50-year-old man complained of unsatisfactory micturition, feeble urine flow, difficulty in initiating urine, dribbling at the end of urine and anxiety regarding his future and sensitivity to others’ opinions. The patient was diagnosed with BPH based on clinical presentation and the International Prostate Symptom Score (IPSS). After case taking, Staphysagria in LM potency was prescribed based on symptom presentation. Individualised homoeopathic medicine was …

Individualised Homoeopathic Treatment Of Paranoid Schizophrenia With Potentised Phosphorus – A Case Report, R. Bhuvaneswari, Vaiyapuri Sakthivel

Indian Journal of Research in Homoeopathy

Background: Paranoid schizophrenia is a severe mental disorder that affects approximately one percent of the world population, with devastating consequences for affected individuals and their families. Homoeopathy could be an effective alternative mode of treatment and can minimise the consequences of it. This case report aimed to highlight the significance of using only individualised homoeopathic medicines in the treatment of paranoid schizophrenia without conventional medicine. Case Summary: A 30-year-old male complained of someone controlling his mind, someone talking about him. He was suspicious of the food he was served, talked and laughed to himself and slept insufficiently. The case …

Management Of Generalised Anxiety Disorder With Homoeopathic Medicine Calcarea Carbonica In Lm Potency: A Case Report, Punam Kumari, Tushita Thakur

Indian Journal of Research in Homoeopathy

Introduction: Generalised anxiety disorder (GAD) is a common mental health disorder that interferes with daily activities and the quality of life of people.

Case summary: A 38-year-old female patient presented with symptoms of anxiety along with marked fear of some impending misfortune, decreased socialisation and difficulty in managing her day-to-day work and family responsibilities for one year and six months. She was diagnosed with a case of generalised anxiety disorder as per the International Classification of Diseases, Tenth Revision classification of psychiatric disorders. A detailed case taking and repertorisation was done as per homoeopathic principles. The patient was prescribed individualised …

Urinary Bladder And Bilateral Renal Calculi Expelled Through The Homoeopathic Medicine Nux Vomica – A Case Report, Prajakta M. Udmale, Vaishali R. Khobragade

Indian Journal of Research in Homoeopathy

Introduction: Urolithiasis is one of the most common urological problems that one comes across in a general outpatient clinic. The usefulness of homoeopathic medicines in the expulsion of urinary calculus is well-reported. However, this case is unique due to an advanced case of urolithiasis, where complications had begun to appear, as also the expulsion of all calculi using the homoeopathic medicines. Case Summary: A 34-year-old male patient was diagnosed with a large, mobile urinary bladder calculus and small bilateral renal calculi, with hydronephrosis, hydroureter, and mild oedema at ureterovesical (U-V) junction. He presented with recurrent episodes of mild to moderate …

Research Highlights, Himani Garg, Gandham Kumuda

Indian Journal of Research in Homoeopathy

Research Highlights

Factors Associated With The Severity Of Erythema Nodosum Leprosum Reactions, Ita Anggraini, Prima Kartika Esti, Eka Komarasari

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Leprosy is a chronic infection caused by Mycobacterium leprae. Leprosy reactions, including erythema nodosum leprosum (ENL), are induced by immune responses. ENL can cause neurological damage and deformities that result in disabilities. This study aimed to identify factors associated with the severity of ENL to help control the leprosy reactions.

Methods: This was an analytical study on 148 patients with ENL reactions, who were divided into two groups based on the severity of their reactions. A retrospective cross–sectional study was conducted in the medical record unit of Sitanala Hospital, Tangerang, Banten, Indonesia, from May 2022 to …

Effectiveness Of 5% Channa Striata Extract Gel In Wound Healing: A Double-Blind Randomized Controlled Trial, Yulia Farida Yahya, Yuli Kurniawati, Erial Bahar, Theresia Lumban Toruan, Soenarto Kartowigno, Muhammad Izazi Hari Purwoko, Tiar Marina Octyvani

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Snakehead fish (Channa striata, CS) has traditionally been used in Indonesia as a nutrient to promote wound healing. It contains protein highly similar to human protein, which may be involved in wound healing via biological pathways. We aim to determine the effectiveness of the topical 5% CS extract gel in promoting wound healing.

Methods: A double-blind, placebo-controlled randomized clinical trial was conducted from June to August 2022 at the Department of Dermatology, Venereology, and Aesthetics of Dr. Mohammad Hoesin Hospital. We allocated 32 post-skin surgery participants with grade I acute superficial wounds on the face, neck, …

Topical Application Of Exosomes In A Patient With Acne Conglobata: A Case Report, Theressia Handayani, Stefani Luziani

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Acne conglobata (AC) is a rare and severe acne characterized by interconnected nodules, cysts, and abscesses. Mesenchymal stem cell-derived exosomes (MSC-exosomes) have immunosuppressive properties that alleviate inflammation and immunological reactions. We present a case of AC in a patient who received topical administration of exosomes.

Case Illustration: A 20-year-old male was diagnosed with AC, presenting as inflammatory papules and cysts covered with yellowish crusts that had been present for five months. Exosomes (ASCE+®, Seoul, South Korea) were topically administered at a dose of 5 mL, applied evenly to the face. The patient underwent three treatment sessions, with a …

Herpes Zoster Reactivation Following Covid-19 Mrna Vaccination In An Elderly Patient: A Case Report, Ratu Siti Khadijah Sarah, Yari Castiliani Hapsari, Shannaz Nadia Yusharyahya, Eliza Miranda, Sarah Qanita Edwar

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Latent varicella-zoster virus (VZV) in nerve ganglia may reactivate into herpes zoster infection. The coronavirus disease (COVID-19) vaccine is suspected of triggering VZV reactivation, although the exact cause is unclear. This case report aims to raise awareness of the potential complications induced by the COVID-19 mRNA vaccine, particularly in elderly patients.

Case Illustration: A 62-year-old woman complained of itchy and painful unilateral dermatomal herpetiform blisters six days after mRNA COVID-19 vaccination. The vesicle first appeared on the left breast, spreading to the back. The patient has a history of hypertension. After the administration of 800 mg of acyclovir five …

Serial Excision Of A Nevus Sebaceous Of Jadassohn On The Scalp, Belladikna Brillianty Sugiatno, Arif Widiatmoko, Adinda Amalia Dani, Diah Prabawati Retnani

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Nevus sebaceous of Jadassohn (NSJ) is a non-hereditary hamartoma of the skin’s adnexal structures. The incidence of NSJ in newborns is estimated at 0.1-0.3% with no gender or ethnic propensity. Surgical excision is a common treatment for NSJ, although there is no definite consensus on the timing or recommendations for the removal. This article aims to present the advantages of serial excision therapy in a case of NSJ.

Case Illustration: A 14-year-old male presented with a complaint of a bump on the scalp since birth, which had progressively enlarged during puberty. Dermatological examination revealed a well-demarcated, yellow-orange …

Validity And Reliability Of The Indonesian Version Of Nordic Occupational Skin Questionnaire 2002 (Nosq-2002), Listya Paramita, Fajar Waskito, Dikky Prawiratama, Niken Indrastuti, Tuntas Rayinda, Sri Awalia Febriana

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Epidemiological data on occupational hand eczema in Indonesia is still limited, partly because there are no valid and reliable instruments in the Indonesian language as a means of survey. This study aims to translate the Nordic Occupational Skin Questionnaire 2002 (NOSQ-2002) into the Indonesian language and assess the validity and reliability of the Indonesian NOSQ-2002 as an instrument for epidemiological surveys and screening of occupational hand eczema.

Methods: The original English version of NOSQ-2002 was translated into the Indonesian language following the standard procedure of translation. The Indonesian NOSQ-2002 version, which had been collectively approved, was subsequently completed by …

Documenting Our Success Stories: Merits Of Case Reporting In Homoeopathic Research And Practice, Subhash Kaushik

Indian Journal of Research in Homoeopathy

Editorial

Contrast Enhancement, G-Cimp Subtype, And Cdkn2a/B Homozygous Deletion In Idh-Mutant Astrocytoma, Mehak Majid Khan, Wenyin Shi, Iyad Alnahhas

Department of Neurology Faculty Papers

No abstract provided.

Segmental Vitiligo Treated By Homoeopathic Constitutional Medicine Tuberculinum: An Evidence-Based Case Report, Shubham Grover, Ashwini Nair

Indian Journal of Research in Homoeopathy

Introduction: Vitiligo is characterised by a patchy loss of skin pigmentation, which most commonly occurs due to the immune system targeting melanocytes in the epidermis. A few studies have shown the effectiveness of Homoeopathy in halting the progression and replacing the hypo-pigmented patches with normal-pigmented skin. Case Summary: A 15-year-old boy came to the clinic complaining of white patches that appeared suddenly on various parts of his body within one week. Tuberculinum proved to be the constitutional medicine in this case. The photographic evidence taken at regular intervals and a follow-up of over nine months showed the potential of constitutional …

Management Of Leiomyoma And Ovarian Cyst With Homoeopathic Medicine Thuja Occidentalis: An Evidence-Based Case Report, Bharti Wadhwa, Sujata Madhukar, Shweta Singh Kureel

Indian Journal of Research in Homoeopathy

Introduction: Leiomyoma (Uterine Fibroid [UF]) is the most prevalent benign solid tumour arising from the neoplastic transformation of smooth muscle cells of myometrium in the reproductive age of females. Fibroids are rare before puberty, increase in prevalence during the reproductive years, and usually reduce in size after menopause.

Case Summary: A 34-year-old woman presented with a complaint of hypogastric pain, and heavy bleeding during her menstrual periods since 3–4 months. Her menstrual cycle was irregular. She was diagnosed with an intramural UF and a right ovarian cyst on ultrasonography. Thuja occidentalis (in different potencies) was prescribed based on …