Medicine and Health Sciences Commons^™

Enhancing Experiences Of Children With Special Needs And Volunteers In Church Classrooms, Anna Corado

Occupational Therapy Doctorate Capstone Posters

The purpose of this ALE project was to support volunteers working with children with special needs and enhance the experience of children with special needs in church classrooms at Fern Creek Christian Church in Louisville, Kentucky. Volunteers were provided with education and training regarding sensory equipment and strategies to utilize within the classrooms. Changes to the environment were made including creation of a sensory room and adaptations to the classrooms to better support children’s sensory needs. The confidence of volunteers working with children with special needs was measured through a post-survey following the implementation of education and training. This capstone …

Staff Education Project Building Proficiency In Debriefing And Empowering Healthcare Professionals With Confidence And Knowledge, Kristie Lynn Van Waus

Walden Dissertations and Doctoral Studies

Debriefing is a critical reflective practice in healthcare that facilitates team learning, promotes psychological safety, and supports quality improvement following clinical events. Despite its recognized value, healthcare professionals report limited training and a lack of confidence in participating in debriefing. I conducted this staff education project to increase staff knowledge and confidence related to effective debriefing practices by delivering targeted in-person education and measuring outcomes using a pre- and post-intervention knowledge and confidence assessment. The education focused on the essential elements of effective debriefing and use of a standardized data collection form. Participants completed a preintervention assessment measuring their knowledge …

Implementation Of A Patient Engagement Program In A Federally Qualified Health Center, Cami A. Stone

Doctor of Nursing Practice Final Project Abstract

Purpose

The purpose of this project is implementation of a patient engagement program at a Federally Qualified Health Center (FQHC) clinic. This program intends to increase patient self-management of disease without increasing tasks of the clinic staff.

Background

FQHCs have limited resources and staff; their populations are marginalized and transient. The care gap is between the clinic’s resources and patient self-management of disease, specifically hypertension. Evidence shows that personalized coaching of patients aids them with disease self-management.

Methodology

This project delivers personalized coaching via weekly brief phone calls from two assigned nurses to patients, without disrupting clinic duties. Calls involve …

Nursing Education Leadership Succession Planning: Utilization Of Career Mapping For Professional Development, Reba L. Carethers

Doctor of Nursing Practice Final Project Abstract

PURPOSE The focus of this quality improvement project was to identify potential future leaders in the Nursing Professional Development (NPD) department at a large hospital system using a succession planning model, strategy organizations use to cultivate individuals with the potential to assume future leadership roles.

BACKGROUND A gap existed in deliberate career planning within the NPD department. A quality improvement project was developed utilizing evidence-based interventions including development of professional objectives, professional development opportunities, and identification of aspiring leaders in nursing education.

METHODOLOGY Participants developed a career map to outline career goals, created an action plan for their professional development …

Reclaiming Teen Recovery: Tailored Therapeutic Recreation To Boost Engagement, Satisfaction, And Participation, Kabresha R. Potts

Doctor of Nursing Practice Final Project Abstract

Purpose: This QI project evaluated the impact of four tailored group therapeutic recreation modules on six recovery outcomes: satisfaction, engagement belief, participation likelihood, motivation to seek help, perceived usefulness, and perceived importance, among adolescents at a residential treatment facility in Houston, TX, targeting ≥ 20% improvement in each domain.

Background: Adolescents in short-term, often court-mandated, treatment lack personalized leisure activities that promote emotional expression and resilience. Structured leisure engagement is linked to positive affect and treatment motivation, yet interest-based programs for court-involved youth remain underexplored.

Methodology: Using Plan-Do-Study-Act cycles and Self-Determination Theory, weekly 90-minute modules (mindfulness trivia, art Jeopardy, music …

Exposotypes In Psychotic Disorders, Walid Yassin, Bryan Kromenacker, James B. Green, Carol A. Tamminga, Elisabetta C. Del Re, Pegah Seif, Cuihua Xia, Ney Alliey Rodriguez, Elliot S. Gershon, Brett A. Clementz

School of Medicine Publications

Psychiatry lags in adopting etiological approaches to diagnosis, prognosis, and outcome prediction compared to the rest of medicine. Etiological factors such as childhood trauma (CHT), substance use (SU), and socioeconomic status (SES) significantly affect psychotic disorder symptoms. This study applied an agnostic clustering approach to identify exposome clusters “Exposotypes (ETs)” and examine their relationship with clinical, cognitive, and functional outcomes. Using data from individuals with psychotic disorders (n = 1,350), and controls (n = 623), we assessed the relationship between the exposotypes and outcomes. Four exposotypes were identified: ET1 characterized by high CHT and SU; ET2, high CHT; …

Infusing Ot Principles Into A Program For Women Survivors Of Domestic Violence, Lark M. Wilkerson, Mary Jan Greer, Kim Broussard, Wendy Tremaine

Summer 2025 OTD Capstone Symposium

This capstone project proposes the development and implementation of a trauma-informed occupational therapy (OT) program designed to support women survivors of domestic violence. Grounded in trauma-informed care principles, the program aims to address the psychosocial, emotional, and functional disruptions commonly experienced by survivors, including trauma-related stress, anxiety, and difficulty engaging in meaningful daily activities. A comprehensive needs assessment informed the development of structured interventions focused on improving emotional regulation, promoting self-care, fostering social participation, and enhancing overall occupational performance. Using both qualitative and quantitative methods, the project evaluates changes in participants’ functional abilities, psychosocial well-being, and perceived quality of life. …

The Benefits Of Music In Occupational Therapy For Individuals With Dementia, Keanu Butler, Rebecca King, Keegan Mckay

Summer 2025 OTD Capstone Symposium

Alzheimer’s disease is the most common cause of dementia in older adults, leading to progressive declines in memory, behavior, and daily functioning. Music interventions, whether live or recorded, have been shown to improve mood, reduce agitation, and enhance quality of life for individuals with dementia by fostering emotional connection and relaxation. The Model of Human Occupation supports these interventions by addressing volition, routines, and performance skills, helping therapists create meaningful, structured strategies to improve daily living and engagement.

Accessible Outdoor Recreation For Individuals With Physical Disabilities: An Educational Series, Ashlyn Leonard, Zeida Gutierrez

Summer 2025 OTD Capstone Symposium

This capstone paper explores the effects of physical disabilities on outdoor recreation. An educational workshop was designed and delivered to occupational therapy students at the University of St. Augustine for Health Sciences. The purpose of the workshop was to increase their awareness of accessible outdoor recreation that way they can better mitigate barriers experienced by their future clients when trying to participate in desired outdoor activities. A pre- and post-survey was administered and analyzed to determine the applicability and effectiveness of the workshop in delivering the information.

Habit Formation Among Individuals Alcohol Use Disorder, Blaire Guidry, Cynthia Haynes

Summer 2025 OTD Capstone Symposium

This capstone project aimed to determine the efficacy of a newly developed and delivered online program that focuses on educating individuals experiencing Alcohol Use Disorder (AUD) on how to create habits with decreased executive functioning skills. With the rise in substance use and addiction related disorders throughout the United States, the urge to implement various intervention approaches that support long term recovery is crucial (Radesi, 2025). By focusing on habit formation, the goal of this capstone is to educate individuals on how to create habits that promote increased participation in meaningful occupations.

Regional Heterogeneity Of The Blood-Brain Barrier, Marie Blanchette, Kaja Bajc, Benjamin D Gastfriend, Caterina P Profaci, Nadine Ruderisch, Cayce E Dorrier, Guo Zhong, Raquel Cuevas-Diaz Duran, Sean S Harvey, Iris H Garcia-Pak, Lucija Pintarić, Manon Leclerc, Louise Reveret, Vincent Émond, Annette Wang, Deepti Pant, Linus T Tsai, Frédéric Calon, Nina Isoherranen, Sean P Palecek, Eric V Shusta, Jiaqian Wu, Richard Daneman

The Brown Foundation: Institute of Molecular Medicine

The blood-brain barrier (BBB), formed by specialized endothelial cells (ECs), regulates the extracellular composition of the central nervous system (CNS). Little is known about whether there are regional specializations of the BBB that may control the function of specific neural circuits. We use single cell RNA-seq to characterize ECs from nine CNS regions in male mice: cortex, hippocampus, cerebellum, spinal cord, striatum, thalamus, hypothalamus, midbrain, and medulla/pons. Although there is a core BBB transcriptional profile, there are significant regional specializations. Stra6, a retinoid transporter, is highly enriched in the BBB of the nucleus accumbens shell (ShNAc) and ventral cochlear nucleus, …

Improving Effective Assistant Nurse Manager Communication In Obstetrics, Julie Marie Glover

Master's Projects and Capstones

Abstract

Problem: This quality improvement project addresses inconsistent leadership communication among Assistant Nurse Managers (ANMs) in the Obstetrics (OB) department of a hospital in Northern California. ANM and staff concerns around shift handoff, huddles, and leadership responsiveness have created confusion and hindered team coordination. The project aims to improve communication effectiveness scores among OB ANMs from 50% to 75% by July 11, 2025.

Context: The project was conducted in the Maternal-Child-Health (MCH) unit of a hospital in Northern California, specifically targeting communication practices among OB ANMs. Concerns around communication practices were voiced by both ANM leadership and frontline staff, signaling …

In Grief We Need Each Other, Derek Schuurman

University Faculty Publications and Creative Works

In the face of grief, human connections provide a far deeper comfort than new AI developments.

Education Plan On Colonoscopy Preparation And Communication To Improve Colonoscopy Prep And Ensure Better Outcomes, Maryam Pourjalil

Walden Dissertations and Doctoral Studies

This Doctor of Nursing practice (DNP) staff education project introduced a formalized staff education program to refine colonoscopy preparation quality at a community gastroenterology clinic. Suboptimal bowel preparation in 20%–30% of colonoscopies resulted in missed lesions, higher costs, and decreased satisfaction of the provided quality of care, which highlighted the need for enhanced staff education in nursing practice. The project question was: Does the education of staff on colonoscopy preparation procedures bridge the existing knowledge gap regarding modern colonoscopy techniques? My goal was to increase staff knowledge regarding standardize prep instructions. The project was designed using best practice evidence and …

Empowering Medical-Surgical Nurses To Conquer Burnout: Building Resilience And Wellness, Catherine P. Morante

Master's Projects and Capstones

Problem: In the healthcare industry, nurse burnout is a well-documented issue that affects the well-being of both healthcare professionals and their patients. Burnout manifests as intense exhaustion, depersonalization, and diminished personal accomplishment (Okoniewski & Verni, 2024).

Context: Burnout affects patient outcomes and drives up costs (Dall’Ora et al., 2020). When nurses are overwhelmed, attendance is affected (Unpublished confidential document; 2024). Resilient nurses are essential to a healthy, reliable workforce (Unjai et al., 2024).

Interventions: From May to July 2025, a 12-week initiative was launched to reduce the effects of nurse burnout in the workplace. Evidence-based interventions were implemented, incorporating educational …

Enhancing Client Intake Efficiency In The Removal Defense Program: A Nursing-Led Quality Improvement Initiative, Johnny Linares, Julia Tran Ngo, Daniel Orea, Atheana Yadira Lopez

Master's Projects and Capstones

This quality improvement project focuses on optimizing the intake process for the Removal Defense Program at a nonprofit immigration legal office serving asylum-seeking clients. The existing intake relied on unstructured, phone-call-based intake interviews that gathered incomplete information, leading to inconsistent documentation, reduced efficiency, and significant client processing delays. A structured, multilingual, and multiplatform new-client admission protocol coupled with the implementation of a client-facing resource guide for waitlist clients were co-developed and implemented using the Lippitt Change Theory framework. Utilizing a mixed methods approach, the study involved staff interviews and observational assessments with staff members from the program. Baseline intake process …

Mirna-Mediated Regulation Of S100b: A Review, Animesh Dali, Suhana Basnyat, Rachel Delancey, Nipun Chopra

Psychology and Neuroscience Faculty Publications

S100β is a significant signaling molecule and biomarker that is primarily expressed in the brain. At low physiological concentrations, S100β induces astrocyte maturation, microglial migration, and neural proliferation. However, high concentrations activate inflammatory and pro-apoptotic pathways. Due to this dual role, increased research is being invested into the role of S100β in neuronal homeostasis and inflammation. In fact, increased S100β expression is seen in many neuropathologies including Alzheimer’s disease, Parkinson’s disease, cerebral ischemia, and traumatic brain injury. High S100β is generally associated with worsened disease outcome. Here, we provide an overview of the structure and role of S100β in various …

Quality Improvement Project Implementing Comprehensive Foot Exams In Pediatric Patients With Diabetes, Jimmy Penn

Doctor of Nursing Practice Projects

Pediatric patients with diabetes face many of the same long-term complications as adults, including neuropathy. Yet screenings are often overlooked in this population. Research shows that pediatric patients with diabetes experience neuropathy symptoms, yet screening in this population remains underperformed. The purpose of this quality improvement project was to implement a comprehensive foot exam for eligible pediatric patients with diabetes and improve provider adherence through education. The project addressed the question: “Among providers in a pediatric endocrinology clinic, how does implementing education on foot exams, compared to no education, impact provider knowledge and compliance with performing pediatric foot exams over …

Increasing The Feasibility, Impact, And Equity Of The Medicare Annual Wellness Visit (Awv) With A Practice Tailored Awv Intervention: A Stepped Wedge Clinical Trial Protocol, Chi-Hong Tseng, Neil S. Wenger

Faculty Scholarship

Background Older adults vastly underutilize evidence-based preventive health services and screenings that reduce illness, morbidity and mortality. The free-to-patient Medicare Annual Wellness Visit (AWV) is an opportunity to enhance preventive healthcare use, but also is underused. Objectives To evaluate the effect of a practice-tailored intervention on the sustained use of Medicare AWVs and on guideline-recommended preventive services and racial/ethnic disparities in 3 types of practice settings. Methods This is a stepped wedge cluster randomized controlled trial. The intervention will be implemented at the practice level in 24 primary care practices across the country (8 community-based, 8 academic, and 8 serving …

Dietary Protein’S Effect On The Gut Microbiome And Its Metabolites: Protocol Description And Virtual Recruitment Efforts For A Remote Randomized Controlled Trial, Karyn M. Gallivan, Kristin S. Ondrak, Denise M. Danos, Meng Luo, Christopher M. Taylor, Lauren E. Meyer, Ann M. Byerley, Alexander W. Nguyen, Sabyasachi Chatterjee, Jiri Adamec, Lauri O. Byerley

School of Medicine Faculty Publications

Fiber’s effect on our gut microbes has been studied extensively, while knowledge of the effect of protein is sparse. Colonic putrefaction of dietary protein is known to produce several potentially detrimental compounds. This randomized controlled trial (RCT) uses a pre- and post-study design to investigate the effect of consuming higher levels of dietary protein on the gut microbiota and the metabolites it produces. Here, we describe our virtual recruitment efforts and RCT protocol. Potential participants lived throughout the contiguous US. Several recruitment methods were employed, of which email reached the largest group of people (approximately 9,100) and generated a 0.3% …

Staff Education To Reduce Medication Errors In An Outpatient Mental Health Clinic, Oluwatoyin Rotimi

Walden Dissertations and Doctoral Studies

Summary Medication errors are a common concern within the healthcare industry, increasing healthcare costs and harming patients. The Doctor of Nursing Practice (DNP) project focuses on a staff education initiative to improve knowledge regarding using the Bar Code Management System (BCMS) to reduce medication errors in an outpatient mental health clinic. The identified gap in practice was the lack of knowledge on using the BCMS in outpatient mental health. The guiding practice-focused question was “Does educating the intake nurses on the barcode management systems improve knowledge, as evidenced by pre- and post-surveys?” The Analysis, Design, Development, Implementation, and Evaluation (ADDIE) …

Implementation Of Medication Administration Education To Increase Medication Technician Knowledge And Confidence, Nicole C. Yan

Master's Projects and Capstones

Problem: Medication technicians have minimal formal training and education in medication administration. Insufficient knowledge and a lack of confidence present safety concerns, such as medication errors, which decrease the quality of patient care.

Context: The setting is an assisted living facility in the San Francisco Peninsula that provides around-the-clock patient care, promoting independence in a safe and home-like environment for 53 patients.

Interventions: The proposed intervention involves implementing a quality improvement (QI) project to educate medication technicians on medication administration safety. The educational sessions, completed in two in-person sessions, include a PowerPoint lecture, interactive case studies, and group discussion.

Measures: …

Eco-Emotions And Climate Activism In Adolescents, Julianna Sahoo

Master's Projects and Capstones

Background. Youth are especially vulnerable to climate change, both physically and psychologically. Combatting climate change will require a coordinated, global effort. Understanding the motivations and emotions behind climate activism is essential to coordinate efforts to combat climate change.

Methods. This research uses survey data collected from first and second year undergraduates (n=521) at a private, urban university in California in the Fall of 2022. Youth were surveyed on emotions related to climate change, activism, compassion, eco-anxiety, and well-being.

Results. Experiencing positive emotions had a stronger relationship with environmental activism compared to negative emotions.

Conclusion. Results suggest climate change communications should …

Reducing Nulliparous, Term, Singleton, Vertex Cesarean Birth Rate, Roseanna Juarez

Master's Projects and Capstones

Abstract

Problem: Cesarean birth rates for nulliparous, term, singleton, vertex (NTSV) pregnancies in the United States continue to exceed the Healthy People 2030 goal of 23.6%, resulting in preventable maternal and neonatal complications and higher healthcare costs.

Context: This quality improvement (QI) initiative was conducted in a high-acuity labor and delivery unit in California’s Central Valley, an area characterized by maternal health disparities, high rates of comorbidities, and limited access to prenatal care. The goal was to reduce the NTSV cesarean rate to 18.0% by July 31, 2025.

Interventions: Guided by Kotter’s 8-Step Change Theory and the Plan-Do-Study-Act (PDSA) framework, …

Illuminating Leadership Excellence: An Evidence-Based Qi Intervention Reigniting Nurse Leaders From Burnout To Brilliance Using Caring Science And Reflective Practice, Matthew S. Elliott

Master's Projects and Capstones

Abstract

Problem: A 2024 assessment at a 250‑bed Northern California medical center revealed that 76% of 16 inpatient nurse leaders met "high‑burnout" criteria on the Maslach Burnout Inventory, and leader turnover had climbed to 25%, more than triple national benchmarks, threatening patient care quality, financial stability, and alignment with Magnet® and employee engagement goals.

Context: Root causes included pandemic‑era promotions without development support, a task‑oriented leadership culture, and eroding psychological safety (Press Ganey engagement ≈ 30%). An integrative logic model positioned Watson's Caring Science as the theoretical base, Schön's Reflective Model for adaptive learning, and the Prosci ADKAR change framework …

Mental Health And Substance Use Interventions Within Muslim Community Spaces: A Community Based-Participatory Research Proposal, Halah Mansour Alayleh

Master's Projects and Capstones

Background. Muslim Americans face significant mental health and substance use challenges compounded by Islamophobic discrimination, cultural stigma, and barriers to accessing culturally competent services. They also significantly underuse professional mental health services. Purpose. This study aims to collaborate with Muslim communities within the San Francisco Bay Area to develop a replicable intervention framework for addressing mental health and substance use stigma within mosques and other Muslim community spaces. Methods. The proposal uses a community-based participatory research (CBPR) methodology while integrating the theory of planned behavior (TPB) and stigma theory in the framework. This proposal outlines the four phases of intervention …

Micbg406a Polymorphism Reduces Risk Of Mechanical Ventilation And Death During Viral Acute Lung Injury, Harry Pickering, Narges Alipanah-Lechner, Ernie Chen, Dylan Duchen, Holden T Maecker, Seunghee Kim-Schulze, Ruth R Montgomery, Chris Cotsapas, Hanno Steen, Florian Krammer, Charles R Langelier, Ofer Levy, Lindsey R Baden, Esther Melamed, Lauren Ir Ehrlich, Grace A Mccomsey, Rafick P Sekaly, Charles B Cairns, Elias K Haddad, Albert C Shaw, David A Hafler, David B Corry, Farrah Kheradmand, Mark A Atkinson, Scott C Brakenridge, Nelson I Agudelo Higuita, Jordan P Metcalf, Catherine L Hough, William B Messer, Bali Pulendran, Kari C Nadeau, Mark M Davis, Ana Fernandez Sesma, Viviana Simon, Monica Kraft, Chris Bime, David J Erle, Joanna Schaenmann, Al Ozonoff, Bjoern Peters, Steven H Kleinstein, Alison D Augustine, Joann Diray-Arce, Patrice M Becker, Nadine Rouphael, Matthew C Altman, Steve Bosinger, Walter Eckalbar, Carolyn S Calfee, Oscar A Aguilar, Elaine F Reed, John R Greenland, Daniel R Calabrese

Faculty, Staff and Students Publications

MHC class I polypeptide-related sequence B (MICB) is a ligand for NKG2D. We have shown NK cells are central to lung transplant acute lung injury (ALI) via NKG2D activation, and increased MICB in bronchoalveolar lavage predicts ALI severity. Separately, we found a MICB polymorphism (MICBG406A) is associated with decreased ALI risk. We hypothesized this polymorphism would protect against severe SARS-CoV-2 respiratory disease. We analyzed 1,036 patients hospitalized with SARS-CoV-2 infection from IMPACC. Associations between MICBG406A and outcomes were determined by linear regression or Cox proportional hazards models. We also measured immune profiles of peripheral blood and the upper and lower …

Facilitating Engagement And Well-Being In Older Adults Through Personalized Background Music, Anna Heady

Occupational Therapy Doctorate Capstone Posters

This capstone project explores personalized background music as a client-centered intervention to enhance engagement, emotional well-being, and quality of life for older adults in a senior living community. Conducted at Treyton Oak Towers in Louisville, KY, the project integrated meaningful music into daily leisure and social activities. Key goals included building rapport with residents and staff, assessing residents’ functional needs, planning and adapting activities, and incorporating music preferences to support participation and enjoyment. Older adults in long-term care often experience cognitive decline, low motivation, and limited engagement in meaningful occupations. Literature supports music’s ability to stimulate memory, enhance mood, and …

Implementing A Multi-Faceted Approach To Reduce Falls And Enhance Safety In Psychiatric Patients While Improving Nurses Perception While Improving Nurses Perception Of Fall Risk Identification, Shanika King

Doctor of Nursing Practice Final Project Abstract

Purpose: The goal of this quality improvement project was to decrease falls in inpatient psychiatric units by at least 5% within six months, utilizing a multifaceted approach while increasing nurses' ability to identify patients at risk for falls. This project incorporated fall risk assessment, staff education, visual identifiers, and debriefings. Nurse confidence was measured post-intervention using a Likert scale survey.

Background: Psychiatric fall rates range from 13 to 25 per 1,000 hospital days, compared to 3 to 4 in general hospitals. These rates highlight the importance of tailored interventions. This project was completed in an inpatient psychiatric facility in …

Stability Of Micrornas In Serum And Plasma Reveal Promise As A Circulating Biomarker, Erryk S. Katayama, Jonathan J. Hue, Alexander W. Loftus, Semmer A. Ali, Hallie J. Graor, Luke D. Rothermel, Eric R. Londin, Mehrdad Zarei, Jordan M. Winter

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

PURPOSE: To verify the stability and reliability of circulating microRNA (miRNA) profiles in plasma and serum under different processing and storage conditions to inform future applications to circulating biomarker analyses.

BACKGROUND: The development of blood-based methods for early disease detection has become increasingly desirable across various medical fields. RNA profiles have been investigated but have been a challenge due to rapid degradation of the analyte by ubiquitous RNases. miRNAs are short, non-coding regulatory RNAs that are believed to be more stable under certain conditions, large in number, and specific to cell type and disease state. Thus, circulating miRNA profiles hold …