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Full-Text Articles in Medicine and Health Sciences

Secondhand Smoke Exposure Among United States Children With Functional Disabilities: National Health And Nutrition Examination Survey, 2021–2023, Raed A. Bahelah Sep 2025

Secondhand Smoke Exposure Among United States Children With Functional Disabilities: National Health And Nutrition Examination Survey, 2021–2023, Raed A. Bahelah

Population Health Science Publications

Objective

Secondhand smoke exposure (SHSe) poses significant health problems. This study aims to examine the prevalence and factors associated with SHSe among 5–17 years old U.S. children with functional disabilities.

Methods

NHANES 2021–2023 applied Child Functioning Module to assess functional disabilities among 5–17 years old U.S. children. SHSe was defined as living in the same household with a person who is a tobacco smoker.

Results

Over three million (32.9 %) children with functional disabilities were exposed to SHS. Children with functional disabilities had higher odds of SHSe compared with children without functional disabilities (Adjusted Odds Ratio “AOR” =1.79, 95 % …


The Question Of Textbooks In Academic Libraries: To Purchase Or Not? A Scoping Review, Jeanette Aprile, Danielle Aloia, Deborah A. Crooke, Marie T. Ascher Sep 2025

The Question Of Textbooks In Academic Libraries: To Purchase Or Not? A Scoping Review, Jeanette Aprile, Danielle Aloia, Deborah A. Crooke, Marie T. Ascher

NYMC Faculty Publications

Objectives: Textbook costs have escalated for students and the library. The objective of this scoping review is to assist libraries in developing a collection policy for course-required textbooks informed by themes and outcomes recognized in the existing body of research.

Methods: The scoping review was conducted using Arksey and O’Malley’s framework and the JBI Manual for Evidence Synthesis. The team did an environmental scan, constructed a comprehensive search strategy in six databases, and conducted hand and cited-reference searching. Included papers were quantitative or qualitative studies with outcomes described and mapped to prevailing themes.

Results: Nine hundred twenty-three records were identified …


Premenopausal Transition In Neurodivergent Women With Musculoskeletal Syndromes: Mechanisms, Risks, And Neuroinclusive Therapeutics, Piper Hutson, James Hutson Sep 2025

Premenopausal Transition In Neurodivergent Women With Musculoskeletal Syndromes: Mechanisms, Risks, And Neuroinclusive Therapeutics, Piper Hutson, James Hutson

Faculty Scholarship

Neurodivergent women with chronic musculoskeletal syndromes experience disproportionate premenopausal symptom burdens that are poorly characterized in extant clinical paradigms and practice. The compounded interplay of estrogen fluctuations in premenopause with sensory–executive differences and baseline nociception from joint or connective-tissue pathology yields intensified pain, mood dysregulation, and functional decline. Evidence indicates estrogen modulates nociception, neuroinflammation, bone remodeling, and monoaminergic signaling; premenopausal variability magnifies pain, affective lability, and cognitive drift—effects accentuated in autism and ADHD. Coexisting hypermobility, fibromyalgia, or connective-tissue disorders compromise joint integrity and proprioception, increasing susceptibility to estrogen-dependent changes in bone microarchitecture and tendon homeostasis. This article advances an integrative …


Sense Of Belonging Of Bachelor Nursing Students: A Descriptive-Comparative Study, Evangeline Fangonil-Gagalang, Phoebe (Yeon) S. Kim, Justin Schneider, Renee Gregg Sep 2025

Sense Of Belonging Of Bachelor Nursing Students: A Descriptive-Comparative Study, Evangeline Fangonil-Gagalang, Phoebe (Yeon) S. Kim, Justin Schneider, Renee Gregg

Nursing Faculty Publications

ackground: A sense of belonging, defined as acceptance, inclusion, and identity within a group, significantlyinfluences nursing students’ academic and social integration into college. Limited belonging causes studentattrition.Aim: This research explored factors influencing nursing students’ sense of belonging and identified elementspromoting or hindering this feeling.Methods: This is a cross-sectional, descriptive comparative study that was conducted with undergraduatenursing students (N = 201) from multiple campuses at a southwestern U.S. university. Data were collectedvia an anonymous survey using the Department Sense of Belonging and Involvement (DeSBI) tool. Descrip-tive and comparative statistics were analyzed.Results: Campus location significantly influenced students’ sense of belonging. Satellite campus …


Association Of Covid-19 Status With Maternal And Neonatal Outcomes Among Pregnant Women At Mombasa County Referral Hospital, Kenya, Salome Mghoi Rajab Sep 2025

Association Of Covid-19 Status With Maternal And Neonatal Outcomes Among Pregnant Women At Mombasa County Referral Hospital, Kenya, Salome Mghoi Rajab

MSc in Advanced Practice Midwifery

Background: COVID-19 pandemic has raised global concern regarding maternal and neonatal health owing to physiological and immunological changes that may heighten disease severity. Despite the global evidence linking COVID-19 infection with unfavorable pregnancy outcomes, data from Sub-Saharan Africa remain limited. This leaves an essential vacuum in our understanding of how COVID-19 status affects maternal and neonatal outcomes in counties like Mombasa, where health-care system problems may alter risks. Vertical transmission remains a puzzle to be solved.

Aim: To assess the association of COVID-19 status on maternal and neonatal outcomes between March 2020 to March 2022.

Methodology: A …


Macomb Community College Dental Clinic Hosts First “Give Kids A Smile” Event Sep 2025

Macomb Community College Dental Clinic Hosts First “Give Kids A Smile” Event

Journal of the Macomb Dental Society

This feature article covers Macomb Community College Dental Clinic's first Give Kids a Smile event -- a collaboration between students, faculty, and community members.


Articulator Volume 31, Issue 3 Sep 2025

Articulator Volume 31, Issue 3

Metro Denver Dental Society Articulator Magazine

The 3rd Quarter 2025 Articulator magazine, Volume 31, Issue 3, published by the Metro Denver Dental Society (MDDS) magazine, features articles on influential voices in the dental profession. The magazine features articles from ADA's President and President-Elect, from the Health Policy Institute, the host of Dental Soundbites Podcast, and from the dental director of a Colorado Community Health Center.


Help Us, Help You!, Bryan Savage Sep 2025

Help Us, Help You!, Bryan Savage

Metro Denver Dental Society Articulator Magazine

This article celebrates the role of organized dentistry and the many benefits that come with membership in organizations like MDDS and the ADA. It highlights the diverse continuing education opportunities, networking events, and strong advocacy efforts that empower dental professionals to grow their skills, build meaningful connections and have a united voice in shaping the future of the profession. Through shared commitment and active engagement, members help strengthen the dental.


Community Health Centers And The Changing Landscape In Colorado, Ethan Kerns Sep 2025

Community Health Centers And The Changing Landscape In Colorado, Ethan Kerns

Metro Denver Dental Society Articulator Magazine

This article examines the vital role Community Health Centers (CHCs) play in Colorado's oral health landscape, highlighting their delivery of comprehensive, integrated dental services to underserved and low-income populations. The author details how shifting state and federal policy and mounting financial challenges, threaten CHC’s sustainability, which could diminish access to essential dental care for hundreds of thousands and create ripple effects throughout the broader dental system.


Compelled Contraception, Lars Noah Sep 2025

Compelled Contraception, Lars Noah

West Virginia Law Review

Can the federal government insist that people use contraceptives? It may come as a surprise to learn that the U.S. Food and Drug Administration (FDA) has done just that as a condition for allowing access to some pharmaceutical products that create a serious risk of birth defects. Over the last few decades, the agency has demanded that patients using certain teratogenic agents—now numbering over a dozen drugs prescribed for a variety of conditions, ranging from severe acne and psoriasis to multiple myeloma and pulmonary hypertension—agree to avoid becoming pregnant, sometimes for years after completing their course of treatment. Undoubtedly the …


High-Frequency And Conventional Ventilation In Very Low Birth Weight Neonates During Interfacility Transport, Trevor Cabrera, Janelle R. Noel-Macdonnell, Emily Mcnellis Sep 2025

High-Frequency And Conventional Ventilation In Very Low Birth Weight Neonates During Interfacility Transport, Trevor Cabrera, Janelle R. Noel-Macdonnell, Emily Mcnellis

Posters

Background: Very low birth weight (VLBW) neonates (≤1500 grams) transported across neonatal facilities often require advanced respiratory support, including high-frequency ventilation (HFV). While HFV use in this setting has increased, data evaluating its safety and efficacy in the VLBW population remain limited. We hypothesized that HFV will provide a safe modality to transport sick VLBW infants. Objectives: To present a comparative experience of safety and efficacy of HFV and CV in VLBW neonates during interfacility transport. Methods: We retrospectively reviewed neonates ≤1500g who received invasive ventilation during interfacility transport by our transport team between January 2019 and December 2022. HFV …


Discontinuous Or Attenuated Background, Absent Sleep Architecture, Absent Reactivity, And Presence Of Subclinical Seizures On Continuous Electroencephalography Are Associated With Unfavorable Short-Term Outcome Following Pediatric Severe Traumatic Brain Injury​, Xuexin Lu, Ara Hall, Yong Y. Han, Madeline Burdick, Avner Moeded, Isabella Boedefeld, Christian Kaufman, Jessica S. Wallisch Sep 2025

Discontinuous Or Attenuated Background, Absent Sleep Architecture, Absent Reactivity, And Presence Of Subclinical Seizures On Continuous Electroencephalography Are Associated With Unfavorable Short-Term Outcome Following Pediatric Severe Traumatic Brain Injury​, Xuexin Lu, Ara Hall, Yong Y. Han, Madeline Burdick, Avner Moeded, Isabella Boedefeld, Christian Kaufman, Jessica S. Wallisch

Presentations

BACKGROUND/PURPOSE: Accurate prognostication following pediatric severe traumatic brain injury (sTBI) remains challenging. Adult neuroprognostication guidelines recommend the use of prediction models that have not yet been validated in pediatric patients. We hypothesized certain continuous electroencephalography (cEEG) characteristics would be associated with unfavorable short-term outcome. METHODS: This was an IRB-approved, 7-year retrospective cohort study of children aged 1.5-18 years admitted to our PICU from 01/2018-12/2024 with sTBI and receiving cEEG monitoring per institutional standard management protocol. cEEG patterns (background, sleep architecture, reactivity, and electrographic seizure) during the first 12-hours of monitoring were analyzed for association with unfavorable short-term outcome at PICU …


Severe Thiopurine-Induced Myelosuppression In A Pediatric All Patient With The Nudt15 *1/*6 Genotype, Jillian Fry, Keith August, Terrie Flatt Do, Laura B. Ramsey Sep 2025

Severe Thiopurine-Induced Myelosuppression In A Pediatric All Patient With The Nudt15 *1/*6 Genotype, Jillian Fry, Keith August, Terrie Flatt Do, Laura B. Ramsey

Posters

Introduction: Genetic variants in TPMT and NUDT15 that affect the metabolism of mercaptopurine (6MP) are routinely tested for to guide 6MP dosing. Nudix hydroxylase 15 (NUDT15) deficiency can cause myelosuppression when affected patients are treated with 6MP. The NUDT15 *6 allele is classified as having uncertain function by the Clinical Pharmacogenetics Implementation Consortium Guidelines given insufficient data to determine its phenotype. Here, we present the case of a pediatric patient with the NUDT15 *1/*6 genotype experiencing significant mercaptopurine-induced myelosuppression. Case Description: We present a 4-year-old female with standard risk-average precursor B-cell acute lymphoblastic leukemia treated per AALL1731. Exome sequencing reported …


Knowledge, Attitude, And Practice Towards Cervical Cancer Screening Among Women Aged 20 Years And Above In Mysuru, India, Sneha Manosh Kumar, Rashmi S, Amogha Shree Sep 2025

Knowledge, Attitude, And Practice Towards Cervical Cancer Screening Among Women Aged 20 Years And Above In Mysuru, India, Sneha Manosh Kumar, Rashmi S, Amogha Shree

Digital Journal of Clinical Medicine

Background: Cervical cancer remains the fourth most common cancer among women globally and a leading cause of cancer-related mortality in India. Despite being largely preventable through screening, uptake remains suboptimal due to socio-cultural and systemic barriers.

Methods: A community-based cross-sectional study was conducted among 300 women aged ≥20 years residing in urban and rural areas of Mysuru. Data were collected using a pre-tested, semi-structured questionnaire and analyzed with SPSS version 30.

Results: Awareness of cervical cancer was reported by 90% of participants and of screening methods by 80%. However, only 21% had ever undergone screening and 17% within the preceding …


Fire! It Took A Brush With Catastrophe To Get Me To Focus On The Need To Be Prepared To Prevent And Manage A Fire Emergency In The Office., Stuart Segelnick Dds, Ms Sep 2025

Fire! It Took A Brush With Catastrophe To Get Me To Focus On The Need To Be Prepared To Prevent And Manage A Fire Emergency In The Office., Stuart Segelnick Dds, Ms

The New York State Dental Journal

Backing up your office computer data and encompassing your practice management software, your imaging software and everything your office needs to treat patients and do business are essential, for you never know when a disaster might strike, making it crucial to have daily backups of electronic records and office data, preferably both cloud and physical storage. One very prudent recommendation offered to me by the New York City Small Business Service grant program after Hurricane Sandy destroyed my office 13 years ago was to have a battery backup system in my newly built office. This would improve resiliency during a …


Towards Accessibility In Healthcare For Individuals With And Without Hearing Loss: Evaluation Of Usability, Fit, And Communicative Effectiveness Of A Transparent N95 Mask Prototype, Samuel R. Atcherson, Brooklyn Schultes, Jeanne Hahne, Barbara Debaun, Chris Showell Sep 2025

Towards Accessibility In Healthcare For Individuals With And Without Hearing Loss: Evaluation Of Usability, Fit, And Communicative Effectiveness Of A Transparent N95 Mask Prototype, Samuel R. Atcherson, Brooklyn Schultes, Jeanne Hahne, Barbara Debaun, Chris Showell

JADARA

The COVID-19 pandemic has underscored the necessity of effective face masks in both public and healthcare settings for mitigating the spread of disease. However, traditional face masks impede communication, posing significant challenges for approximately 13% of the general population and 10% of healthcare and social assistance workers who have hearing loss and who rely on lipreading and other non-verbal cues. Traditional surgical masks and N95 respirator masks serve important roles in healthcare, but they differ in levels of protection. Currently, a transparent surgical mask is available, but not an N95 version. Thus, this study aimed to evaluate the usability, fit, …


Stand For Support, Shatter The Silence: Administrative Approaches To Eradicate Bullying In Higher Education, Elaine M. Mora, Shawn P. Saladin Sep 2025

Stand For Support, Shatter The Silence: Administrative Approaches To Eradicate Bullying In Higher Education, Elaine M. Mora, Shawn P. Saladin

School of Rehabilitation Services & Counseling Faculty Publications

Bullying in higher education has become a widespread and complex issue that affects staff, faculty, and students worldwide, causing a detrimental impact on both psychological health and academic achievement. This paper provides a comprehensive examination of the phenomenon, encompassing all its manifestations, underlying causes, and significant consequences. The study, which draws on academic literature, outlines the various forms of bullying, including cyberbullying, mobbing, microaggressions, and social exclusion, and highlights the adverse effects these behaviors have on both individuals and academic communities. The research emphasizes how critical it is to comprehend the power relationships that exist in higher education settings and …


Assessing The Impact Of Tungiasis On Children’S Quality Of Life In Kenya, Lynne Elson, Berrick Otieno, Abneel Matharu, Naomi Riithi, Esther Chongwo, Francis Mutebi, Hermann Feldmeier, Jürgen Krücken, Ulrike Fillinger, Amina Abubakar Sep 2025

Assessing The Impact Of Tungiasis On Children’S Quality Of Life In Kenya, Lynne Elson, Berrick Otieno, Abneel Matharu, Naomi Riithi, Esther Chongwo, Francis Mutebi, Hermann Feldmeier, Jürgen Krücken, Ulrike Fillinger, Amina Abubakar

Institute for Human Development, East Africa

Tungiasis is a neglected tropical skin disease caused by the sand flea, Tunga penetrans which penetrates the skin causing considerable pain and itching. In this cross-sectional study we aimed to assess its impact on the quality of life of school children in Kenya. School pupils (198) aged 8–14 years with tungiasis were randomly selected and interviewed using a tungiasis-specific quality of life instrument (TLQI). The caregivers of each infected pupil and 199 randomly selected caregivers of uninfected pupils were interviewed using the proxy KIDscreen52 to assess their child’s general health-related quality of life (HR-QoL). Generalized linear models were used to …


Assessing The Psychological Wellbeing And Resilience Of Frontline Health Workers In Uganda: A Cross-Sectional Study, Ahmed Sarki, Joseph Atukwatse, Gideon Mbithi, Sabina Odero, Mary Namuguzi, Bernard Mutwiri, Lestine Bitakwitse, Peninah Wachira, Kevinson Mwangi, Eunice Ndirangu, Amina Abubakar Sep 2025

Assessing The Psychological Wellbeing And Resilience Of Frontline Health Workers In Uganda: A Cross-Sectional Study, Ahmed Sarki, Joseph Atukwatse, Gideon Mbithi, Sabina Odero, Mary Namuguzi, Bernard Mutwiri, Lestine Bitakwitse, Peninah Wachira, Kevinson Mwangi, Eunice Ndirangu, Amina Abubakar

Institute for Human Development, East Africa

Background: Health workers in the frontline are the major drivers of health systems in low- and middle-income countries. However, these health workers face both chronic and acute shocks and stressors that expose them to mental health problems which are often overlooked. We examined the prevalence of mental health problems, correlates of psychological functioning, and resilience of frontline health workers in Uganda.

Methods: We conducted a cross-sectional study comprising 1800 frontline health workers across all regions of Uganda from August through October 2023. We used tools such as the PC-PTSD-5, PHQ9, PSS, GAD-7, Oldenburg Burnout Inventory, and CD-RISC-10 to assess PTSD, …


Diagnostic Journey In The Recognition Of Oncogenic Osteomalacia, Steven B. Nagelberg, Mihaela Biscoveanu, Barbara Bix, Carrie Andrews, Srinivas Prasad Sep 2025

Diagnostic Journey In The Recognition Of Oncogenic Osteomalacia, Steven B. Nagelberg, Mihaela Biscoveanu, Barbara Bix, Carrie Andrews, Srinivas Prasad

Jefferson Health - Northeast Papers (formerly Aria Health Papers)

A 73-year-old woman with a remote history of successfully treated primary hyperparathyroidism was referred to our office because of multiple skeletal fractures and proximal muscle weakness. Prior laboratory evaluation demonstrated hypocalcemia, vitamin D deficiency, elevated PTH, and elevated alkaline phosphatase. Updated evaluation in our clinic additionally showed hypophosphatemia prompting measurement of serum fibroblast growth factor 23 (FGF23). FGF23 proved to be markedly elevated prompting consideration of tumor-induced osteomalacia. Positron emission tomography with Cu-64 oxodotreotide revealed an enhancing focus in the left thoracic spine that was confirmed on magnetic resonance imaging to be a 1.5-cm extradural mass. The patient underwent surgical …


Summer 2025, Humayun Islam Sep 2025

Summer 2025, Humayun Islam

PMI Newsletter

No abstract provided.


Himmelfarb Headlines - September/October 2025, The George Washington University, Himmelfarb Health Sciences Library Sep 2025

Himmelfarb Headlines - September/October 2025, The George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Headlines (2009 - present)

News, information, and resources relating to Himmelfarb Library that is of interest to patrons.


The Outcomes Of A Structured Bowel Management Programme On Childhood Functional Constipation: A Retrospective Pre – Post Intervention Study, Gunilla Flankegård, Peter Wide, Evalotte Mörelius Sep 2025

The Outcomes Of A Structured Bowel Management Programme On Childhood Functional Constipation: A Retrospective Pre – Post Intervention Study, Gunilla Flankegård, Peter Wide, Evalotte Mörelius

Research outputs 2022 to 2026

Aim: The purpose of this study was to describe and evaluate the effectiveness of a six-month structured bowel management programme (SBMP) for children with therapy-resistant functional constipation (FC). Method: A retrospective review of medical records with a pre-post design was conducted at an outpatient paediatric clinic in Sweden. Bowel frequency, stool form, faecal incontinence, and abdominal pain were compared before and after the intervention. Predictive factors for successful discharge and duration of care through long-term follow-up were calculated. Results: Of the 142 children enrolled in the SBMP, 132 completed the programme. Despite previous FC therapy resistance, the SBMP achieved a …


A Large-Scale Multi-Centre Study Characterising Atrophy Heterogeneity In Alzheimer's Disease, Vikram Venkatraghavan, Damiano Archetti, Pierrick Bourgeat, Chenyang Jiang, Mara Ten Kate, Anna C. Van Loenhoud, Rik Ossenkoppele, Charlotte E. Teunissen, Elsmarieke Van De Giessen, Yolande A.L. Pijnenburg, Giovanni B. Frisoni, Béla Weiss, Zoltán Vidnyánszky, Tibor Auer, Stanley Durrleman, Alberto Redolfi, Simon M. Laws, Paul Maruff, Neil P. Oxtoby, Andre Altmann, Daniel C. Alexander, Wiesje M. Van Der Flier, Frederik Barkhof, Betty M. Tijms Sep 2025

A Large-Scale Multi-Centre Study Characterising Atrophy Heterogeneity In Alzheimer's Disease, Vikram Venkatraghavan, Damiano Archetti, Pierrick Bourgeat, Chenyang Jiang, Mara Ten Kate, Anna C. Van Loenhoud, Rik Ossenkoppele, Charlotte E. Teunissen, Elsmarieke Van De Giessen, Yolande A.L. Pijnenburg, Giovanni B. Frisoni, Béla Weiss, Zoltán Vidnyánszky, Tibor Auer, Stanley Durrleman, Alberto Redolfi, Simon M. Laws, Paul Maruff, Neil P. Oxtoby, Andre Altmann, Daniel C. Alexander, Wiesje M. Van Der Flier, Frederik Barkhof, Betty M. Tijms

Research outputs 2022 to 2026

Previous studies identified atrophy-based Alzheimer's disease(AD) subtypes linked to distinct clinical symptoms, but their consistency across subtyping approaches remains unclear. This large-scale study evaluates subtype concordance using two data-driven approaches. In this work, we analyzed data from n=10,011 patients across 10 AD cohorts spanning Europe, the US, and Australia, extracting regional volumes using Freesurfer. To characterize atrophy heterogeneity in the AD continuum, we developed a two-step approach, Snowphlake (Staging NeurOdegeneration With PHenotype informed progression timeLine of biomarKErs), to identify subtypes and atrophy-event sequences within each subtype. Results were compared with SuStaIn (Subtype and Stage Inference), which jointly estimates subtypes and …


Comparison Of Decision-Making Skill In 360° Video To The Field Setting In Highly Skilled Rugby Union Players, Hannah J. Vawser, Khaya Morris-Binelli, Benjamin Piggott, Sean Müller, Paola Chivers, Evan Dekker Sep 2025

Comparison Of Decision-Making Skill In 360° Video To The Field Setting In Highly Skilled Rugby Union Players, Hannah J. Vawser, Khaya Morris-Binelli, Benjamin Piggott, Sean Müller, Paola Chivers, Evan Dekker

Research outputs 2022 to 2026

Little evidence exists of whether decision-making in immersive 360° video is representative of the field setting in sport. The purpose of this study was to investigate whether decision-making performance of a representative exemplar competition specific skill was similar between 360° video and a field task. Fifteen players from skilled junior rugby union pathways and professional rugby union teams in Australia were recruited to complete a 360° video decision-making choice response task involving four attackers and three defenders. Their decision-making was previously assessed in a similar field decision-making task that was representative of rugby game play. Decision-making was scored according to …


History Informing The Future Of Exercise Oncology, Daniel A. Galvão, Kerry S. Courneya, Alejandro Lucia, Anne M. May, Karen Mustian, Allison B. Warner, Wiskemann Joachim, Karen Wonders, Kathryn H. Schmitz, Robert U. Newton Sep 2025

History Informing The Future Of Exercise Oncology, Daniel A. Galvão, Kerry S. Courneya, Alejandro Lucia, Anne M. May, Karen Mustian, Allison B. Warner, Wiskemann Joachim, Karen Wonders, Kathryn H. Schmitz, Robert U. Newton

Research outputs 2022 to 2026

Exercise is increasingly recognized by patients, clinicians, and allied health professionals globally as an important component of cancer care. In this paper, we provide a viewpoint on developments in exercise oncology over the past 4 decades leading up to the creation of the International Society of Exercise Oncology (ISEO). We briefly review research in adult and pediatric cancers from early foundation studies to larger randomized controlled trials published in mainstream oncology journals alongside critical work undertaken in exercise and cancer biological mechanisms. We also discuss potential strengths, weaknesses, opportunities, and threats facing ISEO in becoming a global forum for exercise …


Moderate Coffee And Tea Consumption Is Associated With Slower Cognitive Decline, Stephanie R. Rainey-Smith, Kelsey R. Sewell, Belinda M. Brown, Hamid R. Sohrabi, Ralph N. Martins, Samantha L. Gardener Sep 2025

Moderate Coffee And Tea Consumption Is Associated With Slower Cognitive Decline, Stephanie R. Rainey-Smith, Kelsey R. Sewell, Belinda M. Brown, Hamid R. Sohrabi, Ralph N. Martins, Samantha L. Gardener

Research outputs 2022 to 2026

Background: Globally, coffee and tea are consumed extensively, potentially providing neuroprotection through anti-inflammatory and antioxidative stress effects. Objective: This study aimed to investigate associations between coffee and tea intake and cognitive function. Methods: In a longitudinal prospective cohort study, dementia-free (n = 8715; age range 60.0–85.2 years) older adults from the UK Biobank self-reported coffee and tea intake over the previous year; ‘never’, ‘moderate’ (1–3 cups/day), or ‘high’ (≥4 cups/day). Participants completed cognitive assessments at ≥2 timepoints (mean of 9.11 years). Results: Those ‘never’ consuming coffee and ‘moderate’ coffee consumers (β = 0.06, p = 0.005; β = 0.07, p <  0.001, respectively), as well as ‘moderate’ tea consumers and ‘high’ tea consumers (β = 0.06, p = 0.009; β = 0.06, p = 0.003, respectively) had slower fluid intelligence decline. Additionally, those ‘never’ consuming coffee and ‘moderate’ coffee consumers had a slower increase in pairs matching errors (β = −0.05, p = 0.022; β = 0.05, p = 0.013) compared to ‘high’ consumers. Conclusions: ‘Moderate’ coffee, and ‘moderate’ and ‘high’ tea intake may be a protective factor against cognitive decline. Randomized controlled trials are required to establish causal relationships leading to evidence-based recommendations regarding benefits of coffee and tea intake.


Socioeconomic Disadvantage, All-Cause And Cause-Specific Mortality In Patients Treated With Maintenance Dialysis: A Mediation Analysis Of Geographical Inequity And Multimorbidity, Farzaneh Boroumand, Wai H. Lim, Shuvo Bakar, Ryan Gately, Pedro Lopez, Dharshana Sabanayagam, Anita Van Zwieten, Lin Zhu, Germaine Wong, Armando Teixeira-Pinto Sep 2025

Socioeconomic Disadvantage, All-Cause And Cause-Specific Mortality In Patients Treated With Maintenance Dialysis: A Mediation Analysis Of Geographical Inequity And Multimorbidity, Farzaneh Boroumand, Wai H. Lim, Shuvo Bakar, Ryan Gately, Pedro Lopez, Dharshana Sabanayagam, Anita Van Zwieten, Lin Zhu, Germaine Wong, Armando Teixeira-Pinto

Research outputs 2022 to 2026

Rationale & Objective: Social gradient in health (a “social gradient in health” refers to the observed pattern in which individuals with lower socioeconomic status typically experience poorer health outcomes than those with higher socioeconomic status. This indicates that health disparities exist across different social levels, with the most disadvantaged groups experiencing the worst health outcomes) is significant and established in patients with kidney failure, but the pathways of this relationship are unknown. We aimed to assess the mediating effects of multimorbidity and geographical remoteness in the socioeconomic status (SES)-death associations. Study Design: A cohort study. Setting & Participants: All patients …


Tissue-Specific Distribution Of Microplastics In Human Blood And Carotid Plaques: A Paired Sample Analysis, Cancan Cui, Zheng Guo, Yanxi Liu, Ning Han, Jiayin Song, Yuanmei Chen, Yulu Zheng, Chen Sheng, Lois Balmer, Haibin Li, Rui Liu, Lin Liu, Jianshi Du, Zhiyuan Wu Sep 2025

Tissue-Specific Distribution Of Microplastics In Human Blood And Carotid Plaques: A Paired Sample Analysis, Cancan Cui, Zheng Guo, Yanxi Liu, Ning Han, Jiayin Song, Yuanmei Chen, Yulu Zheng, Chen Sheng, Lois Balmer, Haibin Li, Rui Liu, Lin Liu, Jianshi Du, Zhiyuan Wu

Research outputs 2022 to 2026

Backgrounds: Microplastics (MPs) have been increasingly detected in human tissues, raising concerns about their role in cardiovascular disease. However, their distribution in matched blood and vascular tissues, such as atherosclerotic plaques, remains poorly understood. Methods: Paired blood and carotid plaque samples were analyzed for 12 polymer types of MPs using pyrolysis–gas chromatography–mass spectrometry among twenty patients undergoing carotid endarterectomy. Results: The mean concentration of total MPs was 75.2 μg/g in blood and 432.9 μg/g in plaque. Polyethylene (PE) dominated blood samples (46.5 %), followed by polyvinyl chloride (PVC, 16.8 %) and styrene-butadiene rubber (SBR, 16.3 %). In plaques, MPs were …


Combining Lumipulse P-Tau217 And Aβ42/40 As Confirmatory Tests For Aβ Positivity Prior To Disease-Modifying Therapy, James D. Doecke, Ahmed Chenna, Mintzu Lo, Youssouf Badal, Brandon Yee, Robert Martone, Christos Petropoulos, Christopher J. Fowler, Simon Laws, Stephanie R. Rainey-Smith, Ralph N. Martins, Christopher C. Rowe, Colin L. Masters, John Winslow Sep 2025

Combining Lumipulse P-Tau217 And Aβ42/40 As Confirmatory Tests For Aβ Positivity Prior To Disease-Modifying Therapy, James D. Doecke, Ahmed Chenna, Mintzu Lo, Youssouf Badal, Brandon Yee, Robert Martone, Christos Petropoulos, Christopher J. Fowler, Simon Laws, Stephanie R. Rainey-Smith, Ralph N. Martins, Christopher C. Rowe, Colin L. Masters, John Winslow

Research outputs 2022 to 2026

Introduction: For a blood-based biomarker to be considered a confirmatory test for the detection of abnormal amyloid beta (Aβ) levels, the sensitivity and specificity must be equivalent to that of current cerebrospinal fluid tests. Methods: In the current study we assessed the ability of phosphorylated tau (p-tau)217 and Aβ42/40 from the Lumipulse G p-tau217 and β-amyloid ratio (1-42/1-40) tests, individually and combined, to predict Aβ positron emission tomography status in two sub-cohorts from the Australian Imaging, Biomarkers, and Lifestyle Study of Ageing. Results: Testing an Alzheimer's disease continuum cohort, the area under the curve (AUC), sensitivity, specificity, and accuracy for …