Medicine and Health Sciences Commons^™

The Impact Of Storage Duration And Elevated Temperature On The Biological And Chemical Characteristics Of Whole Milk Powder, Hussein Ali Shaghati, Rawia Mahmood Yousif, Asmaa Ali Awad

Al-Nisour Journal for Medical Sciences

A total of 45 Whole milk powder(WMP) samples from the same brand and batch were collected and tested pre and post-storage under closed conditions at 45–50 °C. during 60, 90, 120, and 150-day intervals. For the chemical indicators of the WMP, there were no significant differences in the content of fat during the different storage intervals, as the fat value was 30.00–29.99%, while the protein percent was 23.23% and did not change significantly during the storage at 60, 90, 120, and 150 days respectively. On the other hand, significant differences occurred in the moisture content, where the moisture value ranged …

The Impact Of Smoking On The Health And Academic Level Of Male High School Students In Anbar, Esraa Abd Al-Karim Marouf

Al-Nisour Journal for Medical Sciences

Many studies have been conducted on the effects of smoking of all kinds on middle and high school students. Furthermore, smoking has recently become normal lifestyle for many university and school students (especially in the preparatory and secondary stages). Where smoking included tobacco cigarettes, e-hookah and hookahs of various types and flavors. As is well known, smoking has many negative effects on health, physical, psychological, cognitive, social and economic aspects. According to the World Health Organization, the use of tobacco leads to catastrophic effects on public health and it’s a direct cause of death for more than 7 million people …

Nanoseal-X: A Theoretical Design For A Phase-Aligned Multifunctional Wound Dressing Based On Chitosan–Ha–Nanoparticle Composite, Mohammed Mahdi Salman Ghadban

Al-Nisour Journal for Medical Sciences

Chronic wounds pose major clinical and economic challenges, especially in patients with comorbidities or impaired healing responses. This study presents NanoSeal-X™, a bioinspired multifunctional wound dressing engineered to address distinct biological demands at each phase of healing. The theoretical construct integrates a dual-layer matrix: a hyaluronic acid-based hydrogel embedded with silver nanoparticles, amoxicillin, and lidocaine, supported by a chitosan-based scaffold. Each component is strategically selected to provide hemostasis, infection control, tissue regeneration, and pain relief. This work presents a theoretical design framework to guide the development of multifunctional wound dressings. NanoSeal-X™ integrates pharmacological and bioactive components aligned with distinct healing …

Therapeutic Potential Of Sh-Hp (His-D-Trp-Ala-Trp-D-Phe-Lys) In Helicobacter Pylori Infection And Acute Gastric Intoxication, Mohammed Mahdi Salman Ghadban

Al-Nisour Journal for Medical Sciences

Helicobacter pylori is a highly prevalent gastric pathogen (colonizing ∼50% of people worldwide) that causes chronic gastritis, peptic ulcer disease, MALT lymphoma, and gastric cancer. Rising antibiotic resistance (e.g. >15% clarithromycin resistance) has compromised standard eradication regimens, necessitating novel therapies. SH-HP (His-D-Trp-Ala-Trp-D-Phe-Lys) is a synthetic hexapeptide analogue of the endogenous hormone ghrelin/GHRP-6, originally developed as a growth hormone secretagogue. Preclinical studies reveal that SH-HP/GHRP-6 has potent gastroprotective and anti-inflammatory effects: it prevents stress-induced gastric mucosal lesions and mitigates multiorgan damage in ischemia/reperfusion models. Given that ghrelin receptor signaling plays a key role in gut mucosal defense (via nitric oxide and …

Shohani Hormonal Guard (Shg): A Multifunctional Nutraceutical Approach To Treating Polycystic Ovary Syndrome Through Metabolic, Hormonal, And Anti-Inflammatory Pathways, Mohammed Mahdi Salman Ghadban

Al-Nisour Journal for Medical Sciences

Polycystic Ovary Syndrome (PCOS) is a complex endocrine-metabolic disorder affecting women of reproductive age. It is characterized by ovarian dysfunction, insulin resistance, and hyperandrogenism, often accompanied by an overactive hypothalamic-pituitary-adrenal (HPA) axis. “Shohani Hormonal Guard” (SHG) is a nutraceutical formulation designed to target PCOS pathophysiology via multiple ingredients. We present a comprehensive review of SHG’s components – including inositols, N-acetylcysteine (NAC), berberine, ashwagandha, omega-3 fatty acids, and micronutrients (zinc, magnesium, vitamin B6, vitamin D3/K2, resveratrol, chromium, probiotics, etc.) – and their mechanistic roles and clinical benefits in PCOS. The literature demonstrates that SHG’s ingredients improve insulin sensitivity, modulate cortisol and …

Correlation Of Immunological Biomarkers And Severity Of Pneumonia In Pediatric Patients, Dhifaf Abdulrhaman, Mohammed B Hassan

Al-Nisour Journal for Medical Sciences

Among children under five, pneumonia stands as a major contributor to both illness and death, creating a significant challenge for global health efforts. This study aimed to evaluate the correlation between radiological severity, clinical parameters (such as fever and oxygen saturation), and laboratory markers (including CRP levels, white blood cell count, and the neutrophil-to-lymphocyte ratio) in pediatric patients with pneumonia. A retrospective analysis was conducted on 51 hospitalized children with severe pneumonia admitted to Al Mansour Pediatric Hospital in Baghdad from July 2024 to February 2025. The results revealed a strong association between radiologic severity and clinical indicators, with higher …

The Role Of Regulatory T Cells In Ischemic Heart Disease Patients, Duha Alaa Hassan, Hayfaa Mahmood Fahad, Saad Fadhel Nassar

Al-Nisour Journal for Medical Sciences

Background: Regulatory T cells (Tregs) represent 5–10% of the total T cell population and are known as potent suppressors of the immune system. They are crucial for managing immune activation, ensuring peripheral tolerance, and supporting tissue repair and overall homeostasis. These cells are characterized by the expression of specific biomarkers, including CD4+, FOXP3+, and CD25+. While CD4 and CD25 were initially used for their identification, the discovery of CD25 on other T cell types led to a more precise evaluation of Tregs through the assessment of the intracellular Foxp3 transcription factor.

Objective: The primary goal of this study was to …

Robotic Ureteral Reconstruction For Endometriosis-Induced Strictures: Insights From A Multi-Institutional Experience, Matthew Lee, Sonam Saxena, Kelley Zhao, Cameron Dodd, Randall Lee, Michael Stifelman, Lee Zhao, Daniel D. Eun

Department of Surgery Faculty Papers

PURPOSE: To investigate outcomes of robotic ureteral reconstruction (RUR) in female patients with ureteral strictures caused by peri-ureteral endometriosis lesions.

METHODS: We retrospectively reviewed our multi-institutional Collaborative of Reconstructive Robotic Ureteral Surgery (CORRUS) database to identify all consecutive patients undergoing RUR for surgical management of endometriosis-induced ureteral strictures between 2017 and 2022. Indications for surgery included female patients with radiographic evidence of ureteral strictures and/or decreasing renal function on renal scan. We performed a descriptives analysis of perioperative outcomes in patients who met inclusion criteria. Surgical success was defined as freedom from additional interventions for recurrent ureteral stenosis.

RESULTS: Overall, …

Expansion Of Hand Trauma Transfers At A Level 1 Trauma Center Following Integration With The Assh Hand Trauma Center Network, William Delahoussaye, Madeline Gautreaux, Patrick A. Palines, Ramin Shekouhi, Kelly L. Babineaux

School of Medicine Faculty Publications

Purpose: This study sought to evaluate how joining the National Hand Trauma Center Network (NHTCN) affected the volume, demographics, and severity of hand trauma transfers to our institution. Methods: Data for this study were collected retrospectively over a 6-year period from 2016 to 2021 from our institutional trauma registry. Patients were selected based on the criterion of being transferred to our facility because of isolated hand trauma. Analyses of transfer rates, transfer distance, sending facilities, injury patterns, insurance type, path of care, and hospital charges prior to and after joining the NHTCN were performed. Results: There was a total of …

Male Hypogonadism: Recommendations From The Fifth International Consultation On Sexual Medicine (Icsm 2024), Mohit Khera, Luiz Otavio Torres, Ethan D Grober, Abraham Morgentaler, Martin Miner, Thomas Hugh Jones, Jesse N Mills, Andrea Salonia

Faculty, Staff and Students Publications

Introduction: Male hypogonadism is a clinical condition combining low circulating testosterone (T) and specific signs and symptoms associated with impaired hormone production.

Objectives: To provide the 5th International Consultation for Sexual Medicine consensus paper with recommendations concerning management strategies for hypogonadism.

Outcomes: A narrative review combined with expert opinions on major topics concerning diagnosis of male hypogonadism; treatment options; T impact toward cardiovascular, metabolic, sexual, and reproductive health; and prostate cancer (PCa).

Methods: A consensus panel was held with leading Sexual Medicine experts during the 5th ICSM. Relevant English-language peer-reviewed literature was reviewed with a focus on research from but …

Perioperative Repercussions Of Cannabis Use-Implications For Gi Endoscopy Sedation, Basavana Goudra, Michael Green

Department of Anesthesiology Faculty Papers

The legalization of cannabis in multiple U.S. states and several other countries, along with its increasing social acceptance across diverse demographic and socioeconomic groups, has led to a growing number of patients presenting for interventional procedures with a history of cannabis use. Although anesthetic and sedation-related implications may be less pronounced than in major surgery, they remain clinically relevant and warrant careful consideration. Key factors include acute intoxication, chronic use, and cannabis use disorder. Cannabis users often require higher-and sometimes unpredictable-doses of propofol and other sedatives. Inhalational use is associated with airway hyperreactivity, increasing the risk of bronchospasm and, in …

Radiological Insights Into Spina Bifida Occulta In Adults: Unveiling The Hidden Defect In The Lumbosacral Spine Of The Northern Indian Population At A Tertiary Care Centre, Binita Chaudhary, Ruchika Narayan, Prem Kumar, Bijaya N. Nayak, Padamjeet Panchal

Sultan Qaboos University Medical Journal

Objectives: Spina bifida occulta (SBO) is a congenital spinal defect characterised by incomplete closure of the posterior neural arch. Despite its clinical relevance, discrepancies remain in the published literature. This study aimed to determine the distribution pattern and prevalence of SBO in the Northern Indian population using three-dimensional reconstructed specimens of the lumbosacral spine. Methods: This retrospective study was conducted between March 2023 and November 2024 at the All India Institute of Medical Sciences Patna, India. A total of 241 computed tomography (CT) scans of the spine from patients aged over 18 years were analysed. Three-dimensional images were reconstructed …

Advancing Modified Barium Swallow Pre-Sorting With Deep Learning: A New Paradigm For The First Step Analysis In X-Ray Swallowing Study, Shitong Mao, Mohamed A Naser, Sheila Buoy, Kristy K Brock, Katherine A Hutcheson

Faculty, Staff and Student Publications

Purpose: Modified barium swallow (MBS) exams are pivotal for assessing swallowing function and include diagnostic video segments imaged in various planes, such as anteroposterior (AP or coronal plane) and lateral (or mid-sagittal plane), alongside non-diagnostic 'scout' image segments used for anatomic reference and image set-up that do not include bolus swallows. These variations in imaging files necessitate manual sorting and labeling, complicating the pre-analysis workflow.

Methods: Our study introduces a deep learning approach to automate the categorization of swallow videos in MBS exams, distinguishing between the different types of diagnostic videos and identifying non-diagnostic scout videos to streamline the MBS …

Benefits Of Intergenerational Programming In Occupational Therapy, Rachel Mitchell

Honors Theses

Occupational therapy helps clients work toward their meaningful occupational goals. Within this career, a person’s roles and habits are also addressed and taken into account when creating intervention plans. Many individuals live in a multi-generational home, living with others of different generations, or even interacting with them in their daily lives. Intergenerational programming is designed to bring people of different generations together. Whether the client lives with someone from a different generation, or sees them in their life, it is vital to have an understanding of each other. Areas that can be addressed include mental health, cultural identity, social isolation …

Noda News October 2025

New Orleans Dental Association News

New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.

Markers Of Tissue Hypoperfusion And Response To Vasopressors In Patients With Septic Shock, Islam M. El-Desoky, Ahmed A. Abdelaziz, Hossam A. Galbt, Ahmed S. Abdelgawad, Ola S. Mohamed

Journal of Medicine in Scientific Research

Background Patients in the early stage of septic shock require individualized fluid resuscitation and early administration of vasopressors to ensure tissue perfusion. We aimed to assess the performance of tissue perfusion markers in patients with septic shock and assessing its role in predicting the response to vasopressors. Methods This observational study was included 90 patients with septic shock within the first 24 hours of admission to the intensive care. Arterial (a) and central venous (cv) blood samples were obtained before beginning vasopressors (T0), and then at 12 and 24 hours after the initial sampling (T12, 24) for analysis of oxygen …

Racially-Motivated Discrimination Distress And Tobacco Use Outcomes Among Adolescents In The United States, Raed A. Bahelah, Osayande Agbonlahor, Bernadette Grayson, Thomas Dobbs

Population Health Science Publications

Introduction

Racism and discrimination are a public health problem. This study aims to examine the association of racially-motivated discrimination distress using the Adolescent Discrimination Distress Index (ADDI) and its subscales – institutional, educational, and peer – with tobacco use outcomes.

Methods

Weighted logistic regression was used to model the effect of discrimination on past 30-day tobacco use, poly-tobacco use, use frequency, tobacco dependence, intention to quit, and history of quit attempt using data from the 2023 National Youth Tobacco Survey.

Results

Approximately 53.9% (> 12 million) of adolescents reported discrimination. Higher ADDI scores were associated with higher odds of tobacco …

October 3, 2025 — Letter To Cms On Recent Guidance For The Rural Health Transformation Program, American Dental Association

Advocacy in Action letters

No abstract provided.

Detection Of Serotypes And Knockdown-Resistance Mutations In Dengue And Other Flavivirus Samples Collected From Mengare Island, Indonesia, Tasya Amalia Dwiyanti, Teguh Hari Sucipto, Khoirunnisa Suhandarini, Azizia Kanya Fathiarachman, Helena Putri Nastiti, Anika Rahma Putri, Shifa Fauziyah, Prihartini Widiyanti, Hariyono Hariyono, Saifur Rehman

Folia Medica Indonesiana

Dengue fever, caused by the dengue virus (DENV), poses a significant public health challenge, particularly in tropical regions. This study aimed to detect flavivirus presence, DENV serotypes, and knockdown-resistance (kdr) mutations in mosquito samples collected from Mengare Island, Gresik, Indonesia. A cross-sectional experimental design was employed, utilizing reverse transcription polymerase chain reaction (RT-PCR) for flavivirus detection and serotyping, as well as for identifying kdr mutations. Ribonucleic acid (RNA) extraction was performed using the Quick-RNA\texttrademark Miniprep Plus Kit (Zymo Research, Irvine, CA, USA), followed by RT-PCR with specific primers for DENV serotypes 1–4 and kdr mutations (V1016G and F1534C). …

Impact Of Microplastics Contaminated Food And Beverages On Reproductive And Mental Health, Lala Opeyemi Titilayo, Adisa Ayomide Funmilayo, Adelowo Joy Motunrayo, Oladapo Jesutomi Eniola, Oyekanmi Bolape Adeola, Lala Olusegun Gbenga, Afolabi Opeyemi Olanike, Ajayeoba Titilayo Adenike, Morakinyo Adetoun Elizabeth, Oladipo Elijah Kolawole, Oyowvi Mega Obukohwo, Oyedepo Temitope Adenike

Folia Medica Indonesiana

Microplastics, defined as plastic particles smaller than 5 mm, have emerged as a global environmental pollutant resulting from widespread plastic waste. Increasing concerns have been raised regarding their potential contamination of food and beverages, which may pose health risks to humans. This review aimed to evaluate current literature focusing on potential reproductive and mental health risks associated with the consumption of microplastic-contaminated food and beverages. A comprehensive literature search was conducted using multiple databases and Boolean operators to identify peer-reviewed English-language articles published within the past thirteen years. The review included studies that addressed microplastics in food and beverages, their …

The Effect Of Astaxanthin On Tumor Necrosis Factor Alpha (Tnf-Α) And Interleukin 10 (Il-10) Expression In Uv-B-Induced Rats Model, Akhmad Setyo Rahman, Theresia Indah Budhy, Jusak Nugraha, Nur Lailatul Fadhilah

Folia Medica Indonesiana

The skin, the largest organ in the human body, serves as a protective barrier against external factors. Exposure to UV-B radiation accounts for approximately 90% of skin damage, leading to aging characterized by dryness and wrinkles. Proper nutrition has been associated with skin repair and delayed aging. Astaxanthin, known for its pharmacological properties including anti-cancer, anti-diabetic, anti-inflammatory, and antioxidant activities has garnered attention for its ability to improve damaged skin when administered as a daily supplement. This study investigated the roles of TNF-α and IL-10 as inflammatory markers in skin damage and repair, which remain underexplored. A true experimental randomized …

The Effect Of Mlc901 On Red Cell Distribution Width (Rdw) As A Predictor Of Acute Ischemic Stroke Outcome In Acute Ischemic Stroke Model In Rats, Muhammad Arya Rifqi Ilham, Ilsa Hunaifi, Bayu Tirta Dirja

Folia Medica Indonesiana

Stroke is the second leading cause of death globally, with ischemic stroke being the most prevalent type. Thrombolysis is the standard treatment for ischemic stroke; however, the rate of thrombolysis administration remains low. Therefore, neuroprotective therapies such as MLC901 are considered promising alternatives. The role of MLC901 in influencing red cell distribution width (RDW) during pathological ischemic stroke remains unclear. Hence, research on the effect of MLC901 on RDW is warranted. Male rats (n = 15) were divided into three groups: (1) acute ischemic stroke treated with MLC901 at a dose of 43.2 mg, (2) acute ischemic stroke treated with …

Motivation And Experiences Of Individuals With Opioid Use Disorder And Chronic Pain Using Medical Cannabis For 12 Months., Michelle R. Lent, Karen L Dugosh, Kartik Varsani, Andrea Jonsson, Tyler Kung, Katherine E. Galluzzi

PCOM Scholarly Works

BACKGROUND: The objective of this qualitative study was to better understand the experiences of individuals living with opioid use disorder (OUD) and chronic pain using medical cannabis (MC) for 12 months.

METHODS: Perspectives were captured via 10 key informant interviews conducted after 12 months of treatment with MC RESULTS: Key themes identified regarding the reasons for initially pursuing MC included: (1) cannabis supply safety; (2) a desire to reduce or eliminate prescription medication usage for pain, OUD and mood; (3) to induce feelings of calm or relaxation; and (4) to improve levels of chronic pain. At 12 months, key themes …

Analysis Of Transcripts And Cardiac Myosin-Binding Protein With Variants Of Uncertain Significance In Cardiomyocytes, Egas Manuel Guterres, Luis Manuel Guterres

Folia Medica Indonesiana

Mutations in the myosin-binding protein C (MYBPC3) gene, particularly variants of uncertain significance (VUS), are associated with cardiomyopathies. This systematic review aims to analyze the impact of VUS mutations in MYBPC3 on transcripts and proteins in cardiomyocytes. A comprehensive literature search across multiple databases (i.e., PubMed, Google Scholar, and ScienceDirect) identified relevant studies focusing on the effects of these mutations on transcript and protein levels. Additionally, exclusion criteria were applied, and studies were excluded if they did not focus on cases analyzing transcript levels and MYBPC3 protein behavior in cardiomyocytes harboring VUS mutations. A total of fifteen studies published between …

Alternative And Traditional Schooling On Sexual Risk Behaviors Among Alaska Native Youth In The Lower Kuskokwim, Nathaniel Hebert

Walden Dissertations and Doctoral Studies

Alaska Native youth experience disproportionately high rates of sexual risk, yet disaggregated data and school-contextual analyses remain limited. Understanding how school type (alternative vs. traditional) and individual factors influence sexual risk among Alaska Native youth is essential for informing targeted, culturally responsive health interventions and addressing ongoing health disparities. This quantitative study aimed to examine the association between three behaviors (condom use, multiple sexual partners, and substance use) by school type, controlling for gender, grade level, body mass index, and afterschool activity. Guided by the social-ecological model, this cross-sectional study provided new insights into the relationship between school type and …

Does Staff Education About Diabetic Self-Management Improve Knowledge And Intent To Educate Their Patients?, Bambi Lee Lane

Walden Dissertations and Doctoral Studies

This doctoral project was an education program for staff aimed at increasing their knowledge about diabetic self-management compliance. With improved knowledge, they will be better prepared to educate their patients. Diabetes is a highly complex disease that requires self-management care, including monitoring of blood glucose levels, control of diet, and medication adherence. Despite extensive pharmacology and diet counseling, irregularities between staff training and education program implementation have led to variable results in patients' compliance and control of glycemia at the project site. The significance of such an issue lies in its direct impact on patient morbidity, avoidable complications, and increased …

Addressing The Impact Of Workplace Violence On Staff Injury And Turnover Rates, Kia Denae Walker

Walden Dissertations and Doctoral Studies

This is an evaluation of a quality initiative (QI) project to determine the effectiveness of the 2023 workplace violence prevention training program in reducing workplace violence-related injures increasing the staff’s self-reported confidence in managing violence-related injuries and increasing the staff’s self-reported confidence in managing violent incidents during the six-month evaluation period. The objective of this QI evaluation project was to analyze the effectiveness of staff education intervention in reducing workplace violence and its costs. The level of increase in staff’s knowledge, level of compliance with safety measures, and number of violence-related cases and claims was the focus of the post-implementation …

Staff Education Program To Increase Staff Knowledge On Evidence-Based Practices To Reduce Falls, Ariella Carrenan

Walden Dissertations and Doctoral Studies

Falls among older adults in long-term care facilities constitute a pressing concern, affecting 30% to 40% of residents each year due to physiological changes associated with aging. Such incidents precipitated injuries, extended hospitalizations, elevated healthcare costs, and increased the potential for legal liabilities. This project investigated the effect of a structured educational intervention on nursing staff knowledge of fall prevention strategies in a long-term care facility where the fall rate of 3.4% exceeded the state average of 2.5% and the national average of 3.3%. The project explored the question: In a long-term care facility, does staff education increase staff knowledge …

Ambient Fine Particulate Matter, Residential Greenness, And Childhood Cancer Risk By Trimester Of Exposure In Minnesota 2000 To 2014: A Case-Control Study, Cassandra J Clark, David Haynes, Zhanni Lu, Jeannette M Sample, Laura A Mcguinn, Thanh T Hoang, Philip J Lupo, Michael E Scheurer, Erin L Marcotte, Lindsay A Williams

Faculty, Staff and Students Publications

Background: Outdoor air pollution is a suspected risk factor for childhood cancer, and there is some evidence that greenness may reduce cancer risk. We examined relationships between prenatal exposure to ambient fine particle air pollution [particulate matter < 2.5 µg/m3 (PM2.5)], greenness, and childhood cancer risk in Minnesota.

Methods: Cases included individuals born in the state of Minnesota and reported to the Minnesota Cancer Reporting System between 2000 and 2014 (n = 1272, ages 0-14 years at diagnosis) and birth year-matched cancer-free controls (n = 5245). We used Network Common Data Form to estimate monthly PM2.5 exposure and the normalized difference vegetation index for census tract-level greenness. We estimated ORs and …

All-Optical Voltage Interrogation For Probing Synaptic Plasticity In Vivo, Jacques Carolan, Michelle A Land, Xiaoyu Lu, Maxime Beau, Dimitar Kostadinov, François St-Pierre, Beverley A Clark, Michael Häusser

Faculty, Staff and Students Publications

Measuring synaptic efficacy and defining the rules for induction of synaptic plasticity at identified connections in the mammalian brain is essential for understanding how synapses contribute to learning and memory. This requires new approaches to selectively evoke presynaptic activity and measure postsynaptic responses with high spatiotemporal resolution and high sensitivity over long periods in vivo. Here we develop an all-optical approach to probe synaptic plasticity at identified cerebellar synapses in awake, behaving mice. We developed and applied JEDI-2Psub, a genetically encoded voltage indicator with increased sensitivity around resting membrane potentials, to record subthreshold and suprathreshold activity in Purkinje cell (PC) …