Medicine and Health Sciences Commons^™

Molecular Epidemiology Of Mycobacterium Tuberculosis In The Middle East And North Africa: A Systematic Review And Meta-Analysis, Tsegaye Shamebo, Aboma Zewude, Temesgen Mohammed, Atef Oreiby, Mohammed Saleh Albreiki, Yassir Mohammed Eltahir, Robert Barigye, Markos Tibbo, Ali Artaman, Gobena Ameni

All Works

Objective The objective of this article was to conduct a comprehensive systematic review and meta-analysis on the molecular epidemiology of Mycobacterium tuberculosis in the Middle East and North Africa. Methods PubMed, Scopus, Web of Science, Embase, and Google Scholar databases were used for literature search on the molecular epidemiology, clustering rate and recent transmission index of Mycobacterium tuberculosis complex (MTBC) published between 1 January 2000 to 31 December 2025. The study quality was assessed using the Newcastle-Ottawa Scale (NOS) and meta-analysis was carried out using R statistics version 4.5.3. Results Fifty-nine studies reported 13,194 Mycobacterium tuberculosis (M. tuberculosis) isolates of …

Improving Assessment And Documentation Adherence In An Age-Friendly Health System With A Focus On "What Matters", Thelma I. Arzu

Doctor of Nursing Practice Final Project Abstract

Purpose

To improve adherence in assessing and documenting “What Matters” (WM) using a standardized assessment and documentation process.

Background

The project was implemented within a large Age-Friendly Health System (AFHS) in Houston, Texas, comprised of a geriatric outpatient clinic and a House Call program. Although the 4Ms of AFHS were regularly documented in the outpatient setting, there was limited documentation in the House Call Program.

Methodology

A standardized process was established with clinician stakeholders to assess and document WM using simplified assessment criteria, the electronic medical record (EMR) 4Ms documentation phrase, and a designated location for the 4Ms phrase in …

Dean's Report- Fall 2026, Marina K. Holz

GSBMS Dean’s Report

No abstract provided.

Clinical Presentations, Treatments, And Outcomes Of Pediatric Lupus Nephritis: A Prospective Cohort Study From The Pediatric Nephrology Research Consortium., Melonie Phillips, Mahmoud Kallash, Chloe Tang, Steve Rust, Kia Jubert-Bacon, Scott Wenderfer, Smriti Mohan, Neal Blatt, Don Batisky, Alejandro Quiroga, Tetyana L. Vasylyeva, Nilka Dejesus, Jerome C. Lane

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: There are few prospective studies of mycophenolate mofetil (MMF) versus cyclophosphamide (CYC) for pediatric lupus nephritis (pLN) and none evaluating rituximab (RTX).

METHODS: The Prospective Pediatric Lupus Nephritis Registry (ProPeL-R) enrolled patients <  21 years within 4 weeks of an initial kidney biopsy diagnostic of pLN. Demographic, clinical, and laboratory data were collected prospectively at enrollment, 3 months, 6 months, and then every 6 months thereafter for up to 5 years of follow-up. For this study, we compared patients receiving initial therapy with corticosteroids (CS) and either MMF (n = 33) vs. CYC (n = 18), and those treated with CS, either MMF or CYC, with RTX (n = 20) vs. without RTX (n = 51).

RESULTS: Histology consisted of 18% class III; 35% class IV; 25% mixed class; and 22% pure class V. Eighty-two percent were female. No significant differences in response or infection rates were identified between those receiving MMF or CYC. There was a significant increase in combined complete (CR) and partial response (PR) at 24 months with RTX use. Overall CR rates at 6 and 24 months were 35% …

Adjunctive Embolization Of Target Vessel Dissections To Improve Suitability For Fenestrated-Branched Endovascular Aortic Repair, Zemia C Ferreira, Hannah V Oden-Brunson, Ying Huang, Steven Maximus, Naveed Saqib, Erin Greenleaf, Thanila A Macedo, Gustavo S Oderich

Faculty, Staff and Students Publications

Suitability of renal-mesenteric target arteries is an essential criterion for fenestrated-branched endovascular aortic repair (FB-EVAR). We describe a staged adjunctive technique of target vessel false lumen (FL) embolization to improve suitability for FB-EVAR in patients with chronic postdissection thoracoabdominal aortic aneurysms (PD-TAAA) and dissection extension into the superior mesenteric artery (SMA). Three patients with SMA dissection and ectasia (diameter > 12-14 mm) underwent staged FL embolization with pre-emptive stent placement to optimize SMA incorporation. Using bilateral transfemoral access with intravascular ultrasound guidance, the proximal SMA true lumen was stented with an 8 L × 39 mm VBX balloon-expandable stent graft (W. …

Allergic And Adverse Reactions To Hearing Aid Materials: Clinical Cases And A Proposed Preventive Screening Questionnaire, Margaret Hanger

AuD Capstone Projects - Communication Sciences and Disorders

Abstract (Case 1)

An adverse reaction of the external auditory canal for an adult hearing aid user

Introduction: Contact dermatitis, an allergic skin reaction triggered by exposure to irritants or allergens, has become more common with the widespread use of in-ear devices such as hearing aids. Prolonged contact may lead to redness, itching, pain, and skin breakdown, potentially impacting device use and user satisfaction.

Case Presentation: An adult male who wears a turban was fitted with binaural in-the-ear hearing aids. Shortly after initial use, he experienced bilateral ear discomfort. His hearing aids were remade to address presumed physical fit issues. …

Tumor Cell-Derived Gremlin1 Correlates With Tumor Progression In Gastrointestinal Cancers, Amanda C. Bean

Summer Research Program Abstracts

No abstract provided.

Growing South Dakota (Fall 2026), College Of Agriculture, Food And, Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 2 Support from donors helping set SDSU dairy graduates above the rest
[Page] 4 A decade of impact: Celebrating 10 years of cow-calf, swine education and research facilitates
[Page] 8 98-year-old donor keeps decades-long scholarship going in honor of late husband
[Page] 11 Looking back at Michele Dudash's tenure in academia
[Page] 12Giving students opportunities, experience to build their futures
[Page] 16 A Jackrabbit's journey in growing agricultural leadership
[Page] 18 Building South Dakota's next generation of rural veterinarians
[Page] 19 Conservation: A family affair
[Page] 20 South Dakota Water Resources Institute finds solutions to South Dakota's water challenges …

Recommendations From Health Research For Children And Adolescents Living In The Kimberley Region Of Western Australia: A Scoping Review, Lisa Cannon, Elizabeth J. Elliott, Andrew Dossetor, Tracey W. Tsang, Md Irteja Islam, Alexandra L. Martiniuk, Habiba Naanai, Tuguy Esgin, Emily Carter, Lauren J. Rice

Research outputs 2022 to 2026

Background: Aboriginal leaders in Western Australia’s Kimberley region have voiced concern that research conducted on their lands is not being adequately used to inform meaningful change. Objective: This scoping review, grounded in an Aboriginal-academic partnership, identifies the child and adolescent health-related research conducted in the region and summarises the authors’ recommendations for knowledge translation. Methods: Drawing on PRISMA-ScR guidelines, we conducted a comprehensive search of multiple databases for publications between January 1967 and June 2025, focusing on children aged ≤ 18 years. Data extraction was conducted using Covidence, and publications were categorised based on the International Classification of Diseases (11th …

The Epidemiology Of Kidney And Urinary Tract Infections In Pediatric Chronic Kidney Disease: Prevalence, Risk Factors And Association With Gfr Decline In The Chronic Kidney Disease In Children Study., Derek K. Ng, Andrea R. Molino, Siyao Zhang, Emily J. Stonebrook, Craig S. Wong, Pratyush Gyawali, Kimberly J. Reidy, Susan L. Furth, Bradley A. Warady, Jeffrey J. Fadrowski, Ckid Study Investigators

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Urinary tract and kidney infections are potential complications in pediatric chronic kidney disease (CKD), especially among patients with congenital anomalies of the kidney and urinary tract (CAKUT). We characterized the prevalence of self-reported infections from childhood through young adulthood; evaluated risk factors; and quantified the association with CKD progression.

METHODS: Infections in the past year were self-reported at annual Chronic Kidney Disease in Children (CKiD) study visits. Age-specific infection prevalences were stratified by sex and CKD diagnoses (glomerular, non-glomerular non-CAKUT, CAKUT low-risk for infections, and three CAKUT high-risk categories: reflux nephropathy, obstructive uropathy, and other high-risk). Repeated measures logistic …

Ceftaroline Pharmacokinetics On Ecmo, A Pediatric Case Report., Kathryn Pavia, Ashton Bellamy, Alaina Burns, Allison Scott, Ethan A. Poweleit

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: In-vitro studies suggest that patients on extracorporeal membrane oxygenation (ECMO) may struggle to achieve therapeutic ceftaroline exposure to treat infections due to antibiotic sequestration within the ECMO oxygenator; however, there are no published data regarding ceftaroline concentrations from patients supported by ECMO.

PATIENT PRESENTATION: Here we present an analysis of ceftaroline pharmacokinetics in a 5-y-old patient supported on ECMO due to influenza-associated necrotizing pneumonia.

RESULTS: A total of nine concentrations were analyzed, including three concentrations prior to cannulation and six on ECMO. ECMO cannulation was associated with a relatively small change in the volume of distribution (0.17 L/kg to …

Adjunctive Middle Meningeal Artery Embolization After Surgical Evacuation Of Chronic Subdural Hematoma: An Updated Meta-Analysis Of Randomized Controlled Trials, Tallal M. Hashmi, Hafsa Arshad Azam Raja, Zain Tariq, Faizan Ahmed, Niraj Arora, Majid T. Aized, Adeel Saleemi, Ameer E. Hassan, Adnan Qureshi, Osama O. Zaidat

School of Medicine Publications

Background: Middle meningeal artery embolization (MMAE) has emerged as a promising adjunctive treatment for chronic subdural hematoma (cSDH); however, the efficacy and safety of adjunctive MMAE compared with surgery alone remains uncertain.

Methods: We systematically searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials from inception through June 2026. Randomized controlled trials comparing adjunctive MMAE plus surgical evacuation with surgical evacuation alone in patients with cSDH were included. The primary outcome was hematoma recurrence. Pooled odds ratios (ORs) with 95% CIs were calculated using a random-effects model.

Results: A total of eight randomized controlled trials were included. The …

Peritoneal Dialysis Catheter Complications In Neonates With Kidney Failure., Shannon Reinert, Maanasa Yarlagadda, Alexander Bondoc, Donna Claes, Stefanie Riddle, Meredith P. Schuh

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Neonates with kidney failure require placement of a peritoneal dialysis catheter (PD-C) shortly after birth. PD-C malfunction and peritonitis, both common in this population, are associated with PD failure. The aim of this study was to describe our center's PD-C-related practices and outcomes in neonates with kidney failure.

METHODS: We performed a retrospective chart review of neonates who required kidney replacement therapy (KRT) within the first 30 days of life from 01/2018-12/2023. We evaluated for PD-C duration, PD-C replacement or revision, and peritonitis.

RESULTS: Twenty-four neonates had PD-C placed for chronic dialysis at a median of 9.7 days and …

The Effects Of C-Arm Positioning On The Accuracy Of Acetabular Reorientation In A Periacetabular Osteotomy Surgical Model, Cameron S. Baller

Summer Research Program Abstracts

No abstract provided.

Sociodemographic Predictors Of Patient Adherence To Timely Follow-Up Colposcopy/Leep After Abnormal Pap Screening, Gigi Baer

Summer Research Program Abstracts

No abstract provided.

Social And Psychological Well-Being Of Aps Clients With Elder Mistreatment And Self-Neglect, Thara Ayyar

Summer Research Program Abstracts

No abstract provided.

Pediatric Insulin Resistance And Obesity In A Mexican Border Population – Associations With Inflammation And Metabolic Disease Risks, Glenda N. Asencio

Summer Research Program Abstracts

No abstract provided.

Prioritising Safe Care For Noncommunicable Diseases: A Call To Action On World Patient Safety Day 2026, Subhash Kaushik

Indian Journal of Research in Homoeopathy

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Raman Spectroscopy Characterisation Of 5c Potency Of Homoeopathic Drugs Nux Vomica, Thuja Occidentalis And Nitricum Acidum, Alfonso Tramontana, Giuseppe Acri, Lucia Denaro, Massimo Mattozzi, Maria Antonietta D'Avanzo, Barbara Testagrossa

Indian Journal of Research in Homoeopathy

Background: The physicochemical characterisation of homoeopathic medicines remains a challenge. Raman spectroscopy is a promising tool for identifying structural modifications in the solvent matrix and specific vibrational ``fingerprints'' induced by the potentisation process. Objective: This study aimed to characterise three remedies (Nux vomica, Thuja occidentalis, and Nitricum acidum - 5C potencies) using Raman spectroscopy to identify specific vibrational markers and evaluate the technique's ability to differentiate between different preparations within a complex matrix. Materials and methods: The drugs were analysed as crushed granules (solid state) and after dissolution in betamethasone disodium phosphate (liquid state). Raman spectroscopy was …

Immunomodulatory Activity Of Bryonia Alba 6c And 30c In Sheep Red Blood Cell-Immunised Mice: Insights From Humoral And Delayed-Type Hypersensitivity Responses, Abanti Goswami, Narasimha Kumar Gv, Vara Prasad Saka, Suneel Prajapati, Bibaswan Biswas, Pankaj Gupta

Indian Journal of Research in Homoeopathy

Background: Malnutrition and infectious diseases compromise immune responses, increasing vulnerability to infections. The introduction of plant-derived immunomodulators, such as Bryonia alba (Bry. alba), is attracting attention due to their lower side effects compared with chemical drugs. In Homoeopathy, Bry. alba has long been utilised to treat a wide range of illnesses, including viral infections, and is recognised for its immunomodulatory properties. Objectives: To evaluate the immunomodulatory effects of Bry. alba 6C and 30C potencies on humoral and delayed-type hypersensitivity (DTH) in sheep red blood cell (SRBC)-immunised BALB/c mice. Materials and methods: Fifty BALB/c mice were divided into five …

A Retrospective Descriptive Profile Of Cancer Patients Seeking Homoeopathic Care In A Semi-Rural South African Setting, Radmila Razlog

Indian Journal of Research in Homoeopathy

Background: Patient profiling renders valuable information about the population's healthcare-seeking behaviours, critical for effective patient management. Khula Natural Health Centre (KNHC) in South Africa provides healthcare to rural communities, within the scope of Homoeopathy. Objective: The study aimed to create a preliminary cancer patient profile of KNHC from April 2017 to August 2024. Method: This retrospective study adopted a descriptive, exploratory design. Anonymised patient data was extracted from the KNHC database. Data that met the inclusion criteria were descriptively analysed to summarise and describe the dataset. Results: Forty-six participants' data, presenting a range of cancers, consulted at KNHC for homoeopathic …

Common Symptoms In Homoeopathy. Are They Really Useless? Results From An Empirical Assessment Of Best Cases Data From A Bayesian Perspective: An Observational Study, José Enrique Eizayaga, Lex L. Rutten

Indian Journal of Research in Homoeopathy

Background: In seeking the homoeopathic medicine that best fits their case, homoeopaths traditionally yield greater value to the most peculiar symptoms, while dismissing those they believe to be common, according to the number of medicines found in repertories' rubrics. Objectives: To assess the validity of the following homoeopathic usual practice notions: common symptoms are useless and prescription should rely on peculiar ones. Methods: Empirical data from the Best Chronic Homeopathic Cases (BCHC) and the COVID-19 cases collection databases were analysed by using a Bayesian approach. Symptoms' prevalence and likelihood ratio (LR) were calculated. Results from three very common symptoms in …

Actinic Lichen Planus Treated With An Individualised Homoeopathic Approach: A Case Report, Aloke Kumar Ghosh, Shilpa Mandal, Ritika Bose, Sumanta Kamila

Indian Journal of Research in Homoeopathy

Introduction: Lichen planus (LP) is an idiopathic chronic inflammatory disorder of the skin and mucous membranes. Actinic lichen planus is a rare photosensitive variant that affects sun-exposed areas and may significantly impair quality of life due to its disfiguring nature. Conventional management primarily involves topical or systemic corticosteroids, which are associated with adverse effects and frequent relapses. Scientific literature on homoeopathic management of actinic LP remains limited. Case summary: A 61-year-old woman presented with pruritic, purple-black plaques over the forehead and was clinically diagnosed with actinic LP persisting for the last five months. Causticum in LM potency was prescribed after …

Treatment Of Exfoliative Dermatitis Using Homoeopathic Dilution Graphites In Lm Potency: A Case Report, K. C. Muraleedharan, Kanishka Gandhi

Indian Journal of Research in Homoeopathy

Introduction: Exfoliative dermatitis is a severe form of skin irritability that causes significant erythema and/or scaling. Most of the time, it is a secondary process, and numerous factors could contribute to the development of this widespread skin condition. Psoriasis is the most prevalent reason for exfoliative dermatitis among all dermatologic disorders. Case Summary: A 49-year-old male presented with skin exfoliation with itching, burning and pain on the whole body for 2 weeks associated with serous discharge from lesions at the back and axillae secondary to psoriasis. A single homoeopathic medication Graphites in LM potencies over two months was prescribed that …

Conventional Medicine, Industry, And Homoeopathy: Between Scientific Paradigms, Economic Interests, And Structural Prejudices, Jozelio F. De Carvalho

Indian Journal of Research in Homoeopathy

This article discusses the key epistemological, economic, and structural factors that contribute to the marginalisation of Homoeopathy within contemporary biomedical science. This integrates information from scientific literature, policy discussions, and historical sources addressing evidence hierarchies, trial design, funding patterns, and institutional determinants of scientific legitimacy in medicine. Examples from systematic reviews, randomised controlled trials, pragmatic studies, and N-of-1 research frameworks are considered to contextualise how methodological models may favour or disadvantage specific therapeutic paradigms. Homoeopathy remains a contested field not only due to conflicting results in clinical studies, but also because classical randomised trial designs may fail to adequately capture …

Homoeopathic Management Of Primary Venous Leg Ulcer With Apis Mellifica: A Case Report, Tejashri V. Thakare, Alfisha T. Shaikh

Indian Journal of Research in Homoeopathy

Introduction: Venous leg ulcers are common chronic lower-limb ulcers, primarily resulting from chronic venous insufficiency, venous hypertension, and impaired venous return. They are associated with oedema, pain, skin changes, restricted mobility, delayed healing, and significant morbidity. Despite conventional approaches such as compression therapy, wound dressings, antibiotics, and surgical interventions, healing may be prolonged, and recurrence is common. Case Summary: A 76-year-old male presented with a three-month history of a non-healing ulcer of the left lower limb, accompanied by oedema, pain, swelling, and difficulty in walking. Based on individualisation of symptoms, Apis mellifica 30C was prescribed. Significant symptomatic relief was observed …

Research Highlights, Gandham Kumuda, Monika Chandyoke

Indian Journal of Research in Homoeopathy

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Encouraging Innovation Through Intellectual Property Rights In Homoeopathy, Parth Aphale, Shashank Dokania, Himanshu Shekhar

Indian Journal of Research in Homoeopathy

NA

Indian Standard For Safe Handling Of Biotherapeutic Products Used In Homoeopathy: Guidelines, Kumar Vivekanand, Indra Gaurav Saxena, Divya Taneja, Shailendra K. Saxena, Shrishti Dixit, Raj Kumar Manchanda

Indian Journal of Research in Homoeopathy

Biotherapeutic products used in Homoeopathy are derived from biological sources of human, animal, microbial and other origins and include pathological and non-pathological preparations such as nosodes and sarcodes. Owing to the biological nature of these materials, their safe handling, preparation, storage, testing and documentation require systematic controls to protect personnel, the public and the environment. The Indian Standard `IS 19901:2026, Safe Handling of Biotherapeutic Products Used in Homoeopathy — Guidelines', provides a comprehensive framework for risk assessment, biosafety classification, containment, determination of first safe dilution (FSD), safety and efficacy evaluation, quality assurance, formulation, dispensing and documentation. The standard also establishes …

Evidence-Based Interventions For Suicide Prevention, Deepthi Gilla

Indian Journal of Research in Homoeopathy

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