Medicine and Health Sciences Commons^™

Political Will, Fall/Winter 2018, Issue 37

Sustain Magazine

No abstract provided.

An Overview Of The Health Profile Of Syrian Refugees Arriving In Kentucky From 2012-2017, Camila Calderon, Annie Rominger

Journal of Refugee & Global Health

Background:

The civil unrest in Syria has led to millions of displaced Syrians. The United States has relocated over 15,000 Syrian refugees, mostly arriving since 2015. Little is known about the health of Syrian refugees entering the United States.

Methods:

Syrian refugees in Kentucky who had a medical screening and documented RHA from October 2012 to September 2017 were included in the study. The information is collected and stored in the Arriving Refugee Informatics Surveillance and Epidemiology (ARIVE) database. This study is a retrospective review of the ARIVE database to describe the general health of the Syrian refugees …

Dmbt1 Inhibition Of Pseudomonas Aeruginosa Twitching Motility Involves Its N-Glycosylation And Cannot Be Conferred By The Scavenger Receptor Cysteine-Rich Bacteria-Binding Peptide Domain., Jianfang Li, Stephanie J Wan, Matteo M E Metruccio, Sophia Ma, Kamran Nazmi, Floris J Bikker, David J. Evans, Suzanne M J Fleiszig

Faculty Publications & Research of the TUC College of Pharmacy

The scavenging capacity of glycoprotein DMBT1 helps defend mucosal epithelia against microbes. DMBT1 binding to multiple bacterial species involves its conserved Scavenger Receptor Cysteine-Rich (SRCR) domains, localized to a 16-mer consensus sequence peptide, SRCRP2. Previously, we showed that DMBT1 bound Pseudomonas aeruginosa pili, and inhibited twitching motility, a pilus-mediated movement important for virulence. Here, we determined molecular characteristics required for twitching motility inhibition. Heat-denatured DMBT1 lost capacity to inhibit twitching motility and showed reduced pili binding (~40%). Size-exclusion chromatography of Lys-C-digested native DMBT1 showed that only high-Mw fractions retained activity, suggesting involvement of the N-terminal containing repeated SRCR domains with …

Seaweeds As Nutraceuticals For Health And Nutrition, Emer Shannon, Nissreen Abu-Ghannam

Articles

Throughout human history, seaweeds have been used as food, folk remedies, dyes, and as mineral-rich fertilisers. Seaweeds as nutraceuticals or functional foods with dietary benefits beyond their fundamental macronutrient content are now a major research and industrial development concept. The occurrence of dietary and lifestyle related diseases, notably type 2 diabetes, obesity, cancer, and metabolic syndrome has become a health epidemic in developed countries. Global epidemiological studies have shown that countries where seaweed is consumed on a regular basis have significantly fewer instances of obesity and dietary-related disease. This review outlines recent developments in seaweed applications for human health from …

The Effect Of Smoking On Kentucky’S Workforce, Michael W. Clark, Jenny A. Minier, Charles J. Courtemanche, Bethany L. Paris, Michael T. Childress

CBER Research Report

Excerpt from the Executive Summary:

Smoking has been estimated to increase health care costs in the United States by $167.5 billion annually (Xu et al. 2015). In Kentucky, smoking adds $2.5 billion in health care expenditures each year. Most of these costs were paid by public programs such as Medicaid and Medicare. While these costs are significant, they represent only a portion of the costs that smoking imposes on society. Smoking also leads to poorer labor market outcomes. Smokers are more likely to be unemployed, earn lower wages, and die prematurely than non-smokers. These negative labor market effects reduce economic …

Applying The Plan-Do-Study-Act (Pdsa) Approach To Community Health Worker Job Satisfaction: Local And Global Perspectives, Wendy R. Thal, Rosalinda Jimenez

Journal of Refugee & Global Health

Community Health Workers (CHW) have been a continuing presence in the world health care arena for several decades. While the work they do is diverse, all abide by local social and cultural “norms” and are stakeholders within the population they serve. [1] While much literature is available on the importance of community health workers in the provision of care in regions with limited access to health care, there is little known on what inspires someone to engage in the role. The World Health Organization purports that building value for these lay health care providers within their community via training, support, …

Health Preferences And Culturally Appropriate Strategies To Reduce Bear Bile Demand In Northern Vietnam, Shannon Randolph, Laura Zhang, Lena Tran, Mai Nguyen, Kimberley Ha

EnviroLab Asia

Animal products, such as pangolin scales, rhinoceros horns, tiger bones, and bear bile have been used in East Asian traditional medicine (TM) for more than 2,000 years. However, markets for medicinal wildlife products have expanded dramatically in countries like China and Vietnam in recent decades where economic prosperity has enabled a larger proportion of the population to afford wildlife products (Olmedo et al. 2017). Related new farming and commercialization practices to meet growing international demand pose environmental and human health risks. Animal products also symbolize shared cultural and historical medical practices that are distinct from the dominant Western medical model.

Phosphonium Polyelectrolyte Complexes For The Encapsulation And Slow Release Of Ionic Cargo, Tristan D. Harrison, Olga Yunyaeva, Aneta Borecki, Cameron C. Hopkins, John R. De Bruyn, Paul J. Ragogna, Elizabeth R. Gillies

Bone and Joint Institute

© 2019 American Chemical Society. Polyelectrolyte complexation, the combination of anionically and cationically charged polymers through ionic interactions, can be used to form hydrogel networks. These networks can be used to encapsulate and release cargo, but the release of cargo is typically rapid, occurring over a period of hours to a few days and they often exhibit weak, fluid-like mechanical properties. Here we report the preparation and study of polyelectrolyte complexes (PECs) from sodium hyaluronate (HA) and poly[tris(hydroxypropyl)(4-vinylbenzyl)phosphonium chloride], poly[triphenyl(4-vinylbenzyl)phosphonium chloride], poly[tri(n-butyl)(4-vinylbenzyl)phosphonium chloride], or poly[triethyl(4-vinylbenzyl)phosphonium chloride]. The networks were compacted by ultracentrifugation, then their composition, swelling, rheological, and self-healing properties …

Learning From Incidents To Reduce The Risk Of Drowning In Swimming Pools: Implementation Of Experience-Based Feedback Regarding Near-Misses In Four Public Facilities In France, Élie Vignac, Pascal Lebihain, Bastien Soulé

International Journal of Aquatic Research and Education

The prevention of sports accidents must rely on a detailed knowledge of accident circumstances and risk factors. Today, very few studies have investigated in depth non-fatal drowning incidents that have occurred in public swimming pools (PSP). Learning from incidents seems likely to advance the knowledge of accident scenarios. This research study aimed to capture minor incidents that might identify safety lessons and preventive measures. Incidents of minor and major aquatic events were collected from four PSPs that had hosted 700,000 bathers per year. About 800 incidents and 300 aquatic rescues performed by lifeguards were recorded within a time frame of …

Depression, Anxiety, And Suicidal Ideation: An Evaluation Of Student Mental Health At Texas A&M — Commerce, Tristan Nelson

Honors Theses

No abstract provided.

Appendices And Codebook For Evaluating Nursing Faculty's Use Of Frameworks And Standards In Information Literacy Instruction: A Multi-Institutional Study, Bethany S. Mcgowan, Laureen Cantwell, Jamie Conklin, Julie Planchon Wolf, Maribeth Slebodnik, Rebecca Raszewski, Sandy Mccarthy, Shannon Johnson

Libraries Faculty and Staff Supplemental Materials

In January 2018, the ACRL Health Sciences Interest Group (HSIG) convened a working group to revise the ACRL Information Literacy Competency Standards for Nursing (2013) into a Framework for Information Literacy in Higher Education for Nursing. For nearly two years, the working group has conducted research to understand how nursing faculty integrate information literacy instruction in nursing education. Results from a review of the literature and surveying of nursing faculty at nine higher education institutions suggest that a majority of nursing faculty are unaware of the ACRL Framework for Information Literacy for Higher Education but are intentional in using the …

Trait Emotional Experience In Individuals With Schizophrenia And Youth At Clinical High Risk For Psychosis, Claire I. Yee, Gregory P. Strauss, Daniel N. Allen, Claudia M. Haase, David Kimhy, Vijay A. Mittal

Psychology Faculty Research

Background: Disturbances in trait emotions are a predominant feature in schizophrenia. However, less is known about (a) differences in trait emotion across phases of the illness such as the clinical high-risk (CHR) phase and (b) whether abnormalities in trait emotion that are associated with negative symptoms are driven by primary (i.e. idiopathic) or secondary (e.g. depression, anxiety) factors. Aims: To examine profiles of trait affective disturbance and their clinical correlates in individuals with schizophrenia and individuals at CHR for psychosis. Method: In two studies (sample 1: 56 out-patients diagnosed with schizophrenia and 34 demographically matched individuals without schizophrenia (controls); sample …

Exploration Of Factors Associated With Perceived Barriers To Cervical Cancer Screening Among Chinese American Women, Wei-Chen Tung, Minggen Lu, Michelle Granner, Jiani Mcdonough, Susan Ervin

Faculty Publications

This study explored factors associated with perceived barriers to Pap smear testing among Chinese American women (CAW). A total of 121 CAW, ages 21–65, living in California and Nevada completed a self-report questionnaire. Data included demographics, prior screening behavior, risk factors, and perceived barriers to screening. Logistic regression models revealed that participants with less education, and who have never been screened were more likely to report (I) worry about getting a Pap smear, (II) expense of a Pap smear, and (III) not knowing where to get a Pap smear. Partner’s resistance to the women’s participation in screening was another barrier …

The Upper East Side Vs Central Harlem: What Is Responsible For The Dermatology Disparities That Shaped These Communities?, Zakiya Cush, Jeffrey Weinberg

Annual SHSP Student Research and Scholarship Day

Very few studies have been done to understand why there is a paucity of dermatology practices in the Central Harlem (CH) community in Manhattan. This ecological and exploratory study will identify factors such as, geographical location, race, socioeconomic status, health care and medical education, as reasons why there is a disparity between the dermatology services in the CH community versus the Upper East Side (UES) of Manhattan. Thus, examining the differences in the neighborhoods as a mediator, it is hypothesized there is a need for increased dermatology practices to CH, as not catering to the clinical needs of a community …

Drug Interactions And Pharmacogenetic Factors Contribute To Variation In Apixaban Concentration In Atrial Fibrillation Patients In Routine Care, Markus Gulilat, Denise Keller, Bradley Linton, A. Demetri Pananos, Daniel Lizotte, George K. Dresser, Jeffrey Alfonsi, Rommel G. Tirona, Richard B. Kim, Ute I. Schwarz

Physiology and Pharmacology Publications

Factor Xa-inhibitor apixaban is an oral anticoagulant prescribed in atrial fibrillation (AF) for stroke prevention. Its pharmacokinetic profile is known to be affected by cytochrome P450 (CYP)3A metabolism, while it is also a substrate of the efflux transporters ATP-binding cassette (ABC)B1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein, BCRP). In this study, we assessed the impact of interacting medication and pharmacogenetic variation to better explain apixaban concentration differences among 358 Caucasian AF patients. Genotyping (ABCG2, ABCB1, CYP3A4*22, CYP3A5*3) was performed by TaqMan assays, and apixaban quantified by mass spectrometry. The typical patient was on average …

What's Happening: September 9, 2019, Maine Medical Center

What's Happening

No abstract provided.

Emg Analysis Of The Neuromuscular Activity During Sit-To-Stand From Different Height Chairs In Water, Antonio Cuesta-Vargas

International Journal of Aquatic Research and Education

The purpose of this study was to use surface electromyography to measure the muscular activity during the sit-to-stand task in water and compare it at three different chair heights. Ten healthy young adults [5 males and 5 females (mean ± SD): age, 22.0 ± 3.1 yr; height, 172.8 ± 9.0 cm; body mass, 63.9 ± 17.2 kg] were recruited for study. We used a telemetry EMG system on the following muscles on the right side of the body: quadriceps (vastus medialis and rectus femoris), long head of the biceps femoris, tibialis anterior, gastrocnemius medialis, soleus, rectus abdominis, and erector spinae). …

Prevalence And Correlates Of Cardiometabolic Multimorbidity Among Hypertensive Individuals: A Cross-Sectional Study In Rural South Asia—Bangladesh, Pakistan And Sri Lanka, Liang Feng, Imtiaz Jehan, H Asita De Silva, Aliya Naheed, Hamida Farazdaq, Samina Hirani Samina Hirani, Anuradhani Kasturiratne, Channa D. Ranasinha, Md Tauhidul Islam, Ali Tanweer Siddiquee, Tazeen Jafar

Community Health Sciences

Objective: To determinate the prevalence and correlates of cardiometabolic multimorbidity (CMM), and their cross-country variation among individuals with hypertension residing in rural communities in South Asia.
Design: A cross-sectional study.
Setting: Rural communities in Bangladesh, Pakistan and Sri Lanka.
Participants: A total of 2288 individuals with hypertension aged ≥40 years from the ongoing Control of Blood Pressure and Risk Attenuation- Bangladesh, Pakistan and Sri Lanka clinical trial.
Main outcome measures: CMM was defined as the presence of ≥2 of the conditions: diabetes, chronic kidney disease, heart disease and stroke. Logistic regression was done to evaluate the correlates of CMM.
Results: …

09-10-2019 Hsc Committee Agenda, Hsc Committee

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.

Incidence Of Intraocular Lens Exchange After Cataract Surgery, Maram E. A. Abdalla Elsayed, Khabir Ahmad, Abdulelah A. Al-Abdullah, Rizwan Malik, Rajiv Khandekar, Hernan Martinez-Osorio, Marco Mura, Patrik Schatz

Department of Surgery Docs

Intraocular lens (IOL) exchange after cataract surgery is unusual but may be associated with suboptimal visual outcome. The incidence of IOL exchange has not been consistently estimated. Such information is invaluable when counseling patients prior to cataract surgery. We examined the incidence of, and indications and risk factors for, IOL exchange after cataract surgery. We also assessed visual outcome of eyes that had an IOL exchange. A cohort design was used to estimate the incidence of IOL exchange and a case-control design to identify factors associated with it. All phacoemulsification surgeries with IOL (n = 17415 eyes) during 2010-2017 and …

Week Of September 9, 2019, New York Medical College

InTouch

• Humayun Islam, M.D., Ph.D., Is Named Interim Chair of the Department of Pathology
• Jennifer Lindelof Starts Second Term as SOM Student Senate President
• NYMC Remembers 9/11
• The Skyline Food Kiosk Is Now Open

Administration Of Naloxone By Prehospital Personnel: A Retrospective Analysis., Kaitlin M Bowers, Judd Shelton, Eric Cortez, Robert Lowe, John Casey, Andrew Little

Pharmacy Articles

Introduction Patient-specific discrepancies in prehospital naloxone administration have been documented. As the opioid epidemic continues to evolve, further evaluation of prehospital naloxone administration practices is needed. The objective of this study was to compare patients who received prehospital naloxone and received an emergency department (ED) diagnosis of opioid overdose with patients who received prehospital naloxone and received an alternative ED diagnosis.  Methods This was a retrospective, multicenter chart review of patients who received naloxone by prehospital personnel for suspected opioid overdose between October 1, 2016, and October 31, 2017. Patients were excluded if age was less than 18 years, naloxone …

Comparison Of Two Commercial Matrix-Assisted Laser Desorption/Ionization-Time Of Flight Mass Spectrometry (Maldi-Tof Ms) Systems For Identification Of Nontuberculous Mycobacteria., Barbara A. Brown-Elliott, Thomas R. Fritsche, Brooke J. Olson, Sruthi Vasireddy, Ravikiran Vasireddy, Elena Iakhiaeva, Diana Alame, Richard J. Wallace, John A. Branda

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Objectives: This multi-center study’s aim was to assess the performance of two commercially-available matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) systems in identifying a challenge collection of clinically-relevant nontuberculous mycobacteria (NTM).

Methods: NTM clinical isolates (N=244) belonging to 23 species/subspecies were identified by gene sequencing and analyzed using the Bruker Biotyper with Mycobacterial Library v5.0.0 and the bioMérieux VITEK MS with v3.0 database.

Results: Using the Bruker or bioMérieux systems, 92% or 95% of NTM strains, respectively, were identified at least to the complex/group level; 62% and 57%, respectively, were identified to the highest taxonomic level. Differentiation between members …

Medical School Watercooler Newsletter - September 8, 2019, Lindsey Lyle

Watercooler Newsletter

This is the September 8, 2019 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Studies examine anti-cancer compound developed at Mitchell Cancer Institute

Game Day T-shirts on sale now

Mark Your Calendar: Pediatric grand rounds set for Sept. 20

USA College of Medicine alumnus returns as trauma and burn surgeon

Exploration Of The Experiences And Viewpoints Of Faculty Members On Continuing Education Webinars: A Qualitative Study, Fatemeh Jafarzadeh-Kenarsari, Kobra Abouzari-Gazafroodi, Fatemeh Zaersabet

The Qualitative Report

Continuing education is necessary to improve the professional knowledge and skills of graduates of medical sciences, which may be implemented via e-learning. This qualitative study aimed to explore the experiences and viewpoints of faculty members participating in continuing education webinars. The participants consisted of 15 faculty members selected purposefully and with maximal variation regarding their sex, age, the field of specialization, academic rank, and work experience. Data were collected through semi-structured individual face-to-face interviews. Data analysis of these transcripts using a qualitative content analysis approach revealed 3 themes and 9 sub-themes. The main themes included “Moving across the boundaries of …

The Skiles Mummy: Care Of A Debilitated Hunter-Gatherer Evidenced By Coprolite Studies And Stable Isotopic Analysis Of Hair, Kirsten A. Verostick, Isabel Teixeira-Santos, Vaughn M. Bryant Jr., Karl Reinhard

Karl Reinhard Publications

The Skiles Mummy (SMM), a naturally mummified adult male from the late archaic period of Lower Pecos Canyonlands of South Texas, represents a unique case of care. SMM is an exceptional mummy within this region due to both the retention of a full head of hair, and having a diagnosed case of megacolon, a complication commonly associated with Chagas disease caused by Trypanosoma cruzi. Stable isotopic analysis of his hair is consistent with a diet incorporating of C₄/CAM plants with some C₃ plants, freshwater resources, and higher trophic level animals. However, the segments of hair most …

Andexanet Alfa Is An Effective Reversal Agent For Factor Xa Inhibitors In Patients That Develop Intracranial Hemorrhage, Joseph Friedli

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Connolly SJ, Milling TJ, Eikelboom JW, et al. Andexanet alfa for acute major bleeding associated with factor Xa inhibitors. N Engl J Med. 2016;375(12):1131-1141. doi: 10.1056/NEJMoa1607887.

High-Dose Finasteride Is An Effective Treatment Modality For Androgenic Alopecia In Postmenopausal Women, Joshua T. Gaudette

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Oliveira-Soares R, Silva JE, Correia M, André M. Finasteride 5 mg/day treatment of patterned hair loss in normo-androgenetic postmenopausal women. International Journal of Trichology. 2013;5(1):22-25. doi: 10.4103/0974-7753.114709.

Improving Patient Experience And Education By Leveraging Technology, Cathy Palleschi, Wendy Osgood, Mark Parker, Cecilia Inman, Alicia Russell, Eileen Shanahan, Erin Pappal

Operations Transformation

It is estimated that 65% of the population are visual learners. With that in mind, a team of cardiac nurses in a large academic tertiary hospital developed a quality improvement project to hopefully improve patient engagement as well the patients’ perception that the nurses explained things in a manner that they could understand.

Baseline patient survey scores for the question, “Nurses Explained Things In A Way That I Understand”, were under the 75^thpercentile for a period of 9 months. A root cause analysis was conducted and it demonstrated numerous reasons for this score.

Several countermeasures were instituted to …

Impact Of Palliative Care Consultation On End Of Life Care Measures: A Retrospective Analysis Of Patients In The Oncology Care Model, Alison Greidinger, Md, Maria Vershvovsky, Md, Evan Lapinsky, Md, Alison Rhoades, Md, Amy Leader, Drph, Vittorio Maio, Pharmd, Jared Minetola, Karen Walsh, Ms, Mba, Valerie Csik, Mph, Cpps, Ruben Rhoades, Md

Department of Medical Oncology Posters

Introduction

• In 2016 ASCO recommended that patients with advanced cancer receive dedicated palliative care (PC) services1. Early PC involvement is associated with lower spending, fewer 30-day readmission rates, decreased chemotherapy administration at the end of life (EOL) and increased hospice referrals2.
• Many patients are not referred and continue to receive chemotherapy and utilize high-acuity services near the EOL.
• The Oncology Care Model (OCM) is a CMS episode-based alternative payment model promoting high-value care.
• We evaluated the effect of PC visits on EOL outcomes including code status (CS) and spending in the last 30 days of life.