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Articles 162301 - 162330 of 325754

Full-Text Articles in Medicine and Health Sciences

Any Shape Or Form: An Online Module For Teaching Medical Students Citation Management In Residency Settings, Erica Heasley, Robyn Rosasco Oct 2019

Any Shape Or Form: An Online Module For Teaching Medical Students Citation Management In Residency Settings, Erica Heasley, Robyn Rosasco

Southern Chapter/Medical Library Association Annual Conference

Objective: To describe how the library’s online tutorial for medical students, “Introduction to Citation Management Tools,” was created and integrated into the College of Medicine’s Residency Preparation Boot Camp. Implemented in 2017, passing the tutorial is still a requirement for completing the boot camp.

Methods: In 2017, the Maguire Medical Library was asked by undergraduate and graduate medical education faculty to create a citation management tutorial for 4th-year medical students preparing to commence their respective residency programs. As part of the College of Medicine’s Residency Preparation Boot Camp, the tutorial needed to provide students with an overview of citation management …


A Librarian's Perspective On Manually Tagging Curriculum For Lcme Accreditation, Melodie Gardner Oct 2019

A Librarian's Perspective On Manually Tagging Curriculum For Lcme Accreditation, Melodie Gardner

Southern Chapter/Medical Library Association Annual Conference

Objective: The objective of this paper is to discuss and share some of the successes and challenges of manually tagging all first- and second-year (M1/M2) curriculum course sessions over the course of five academic years (2014 - 2019).

Methods: As part of the Liaison Committee on Medical Education (LCME) accreditation process, all US medical schools are required to maintain a curriculum database that tracks the number of course hours spent on a selected set of topics outlined in the LCME Functions and Structures of a Medical School; this is usually achieved by building a controlled vocabulary based on Standard 6 …


Shaping The Future Of Information Literacy Research By Health Sciences Librarians: A Bibliometric Study, Alexandria Quesenberry, Lin Wu Oct 2019

Shaping The Future Of Information Literacy Research By Health Sciences Librarians: A Bibliometric Study, Alexandria Quesenberry, Lin Wu

Southern Chapter/Medical Library Association Annual Conference

Objectives: Information literacy (IL) publications have been examined in many disciplines, but there is limited published literature to assess health sciences librarians’ productivity on IL research. This study aimed to examine the status and characteristics of IL research authored by health sciences librarians over the period of 2008 to 2018.

Methods: Bibliometrics, the statistical analysis of publications, was used to assess the indicators of productivity, collaboration, and visibility on IL research by health sciences librarians. Data was collected from Scopus and Web of Science. EndNote software was used to remove duplicates and Rayyan was used to systematically screen search results …


Thinking Outside The Box To Square The Circle: Realigning Library Services With Stakeholder Needs, David Petersen, Rebecca Harrington, Martha Earl Oct 2019

Thinking Outside The Box To Square The Circle: Realigning Library Services With Stakeholder Needs, David Petersen, Rebecca Harrington, Martha Earl

Southern Chapter/Medical Library Association Annual Conference

Objectives: In an age of electronic databases and Google, librarians must find ways to expand library services to meet the needs of patrons who no longer seek some traditional services. How do we identify needs in our organizations that are not being met, and market our abilities to fill those needs while maintaining our identity as librarians?

Methods: With the full support of the library director, whose priority was to update academic and clinical services, newly hired librarians took time to observe the initiatives and goals already established across their respective residency and nursing departments. Despite increased liaison activity, decreasing …


The Burden Of Diarrhea: A Survey Of The Caregivers’ Opinions And Perceptions Of Workload In The Intensive Care Unit, Martha Weatherhead, Alana Trottier, Paul Blakeslee, Erin Corica, John Dziodzio, Kristiina Hyrkas, Sonja Orff, Shawn Taylor, Elizabeth Turner Oct 2019

The Burden Of Diarrhea: A Survey Of The Caregivers’ Opinions And Perceptions Of Workload In The Intensive Care Unit, Martha Weatherhead, Alana Trottier, Paul Blakeslee, Erin Corica, John Dziodzio, Kristiina Hyrkas, Sonja Orff, Shawn Taylor, Elizabeth Turner

2019 Sigma Region 15 Nursing Research Symposium

In the literature, the prevalence of diarrhea in the Intensive Care Unit (ICU) has been reported to be 3.3-78%. The problem is significant to patients and also increases workload burden for ICU staff. Unfortunately, research on this topic is very limited; we found one single study on the impact that diarrhea has on nursing staff workload. Therefore, we conducted a retrospective chart review to describe the prevalence and impact of diarrhea in our organization. For the purposes of this study, we equated diarrhea with type 7 stools as defined in the Bristol Stool Form Scale. In January of 2018, we …


Tell Me A Story As A Bibliotherapy Intervention To Promote Resiliency In Military Children, Katherinemarie Conover Oct 2019

Tell Me A Story As A Bibliotherapy Intervention To Promote Resiliency In Military Children, Katherinemarie Conover

2019 Sigma Region 15 Nursing Research Symposium

Project studied effect on resiliency of Tell Me A Story™ intervention with children of active duty military members. Outcomes included improvement in resiliency and ego-resiliency after attending intervention; boys benefited in reduction of internalizing problem behaviors more than girls.


Educating And Engaging Elders In The Sure Steps® Fall Prevention Program, Karin L. Ciance Oct 2019

Educating And Engaging Elders In The Sure Steps® Fall Prevention Program, Karin L. Ciance

2019 Sigma Region 15 Nursing Research Symposium

Purpose of this project was to determine the effects of reducing the incidence of falls for adults aged sixty five years and older living in their homes. Falls and accidents seldom “just happen” and many can be prevented. This project provided adults >=65 living in their home a safer environmental atmosphere and an ongoing exercise program. VNA staff received training at four additional office sites. The program decreased the fall risk for the sample group.


How To Stop Being A Librarian: Student-Centered Library Guide Design And Content Curation, Melodie Gardner Oct 2019

How To Stop Being A Librarian: Student-Centered Library Guide Design And Content Curation, Melodie Gardner

Southern Chapter/Medical Library Association Annual Conference

Objective: The objective of this paper is to discuss information seeking behavior of digital-native students verses librarians and how this affects the design, layout, and content of effective library guides. Topics covered will include effective content curation for guides, web-user’s behavior patterns, design consistency, and tips & tricks for integrating design and content best practices across a library guide system.

Methods: Springshare’s LibGuides is a platform that allows librarians to create and design topic-centered web pages called Library Guides which contain curated content; including library resources. While librarians generally follow webpage design best-practices in their library guides to increase their …


How One Library's Location Change Impacted Health Information Requests: Comparing Zip Codes And Health Disparities To Shape Library Services, David Petersen, Kelsey Grabeel, Cameron Watson Oct 2019

How One Library's Location Change Impacted Health Information Requests: Comparing Zip Codes And Health Disparities To Shape Library Services, David Petersen, Kelsey Grabeel, Cameron Watson

Southern Chapter/Medical Library Association Annual Conference

Objective In 2014, the Preston Medical Library underwent a radical change, moving from an academic office building to the main floor of a regional medical center. While the library previously served the public, health information requests have substantially increased in volume due to the new location. Each health information request is logged with the subject nature and patron contact information. The objective is: to analyze this data to see if our reach has expanded to counties that previously have not used the service, to see which counties request the most health information, and to ascertain whether more requests are from …


Braving Our Blindspots: Using A Virtual Book Discussion Group To Continue Conversations On Implicit Bias In Libraries, Shannon Jones, Kelsa Bartley Oct 2019

Braving Our Blindspots: Using A Virtual Book Discussion Group To Continue Conversations On Implicit Bias In Libraries, Shannon Jones, Kelsa Bartley

Southern Chapter/Medical Library Association Annual Conference

Diversifying librarianship has been a strategic priority for years yet statistically the profession remains largely white. A contributing factor to this homogeneity is likely implicit bias. An implicit bias occurs when an individual has attitudes toward a group of people or associate stereotypes with them without their conscious knowledge. Growing research indicates that implicit biases impact the decisions that we all make daily. In libraries, it impacts who gets hired, who gets supported, which programs get funded, and which services are offered. The authors planned and facilitated a virtual book discussion group using Mahzarin Banaji and Anthony Greenwald’s book, Blindspot: …


"We Try To Find Something For Whatever Obstacle Might Be In Our Way”: Understanding The Health Information Practices Of South Carolina Lgbtq+ Communities, Vanessa Kitzie, Travis Wagner, Nick Vera, Valerie Lookingbill Oct 2019

"We Try To Find Something For Whatever Obstacle Might Be In Our Way”: Understanding The Health Information Practices Of South Carolina Lgbtq+ Communities, Vanessa Kitzie, Travis Wagner, Nick Vera, Valerie Lookingbill

Southern Chapter/Medical Library Association Annual Conference

Objective: LGBTQ+ people experience health disparities compared to heterosexual, cisgender peers. Individual and systemic barriers produce these disparities. One barrier is informational, as LGBTQ+ people experience challenges when learning about their health needs, navigating the healthcare system, and overcoming obstacles to care. This paper investigates the future of libraries and the health sciences by exploring how they can address these informational barriers.

Methods: This paper reports on ~30 ongoing interviews with LGBTQ+ community leaders from South Carolina (SC) using a semi-structured protocol. The protocol asked participants to discuss their community’s health questions and concerns, how the community addresses them, and …


E Pluribus Unum: Using Google Classroom To Bring Together A Statewide Student And Faculty Cohort, Darra Ballance Oct 2019

E Pluribus Unum: Using Google Classroom To Bring Together A Statewide Student And Faculty Cohort, Darra Ballance

Southern Chapter/Medical Library Association Annual Conference

No abstract provided.


Designing A Poster-To-Publication Campaign For Medical Residents, Carrie Cullen, Stephanie Tomlinson Oct 2019

Designing A Poster-To-Publication Campaign For Medical Residents, Carrie Cullen, Stephanie Tomlinson

Southern Chapter/Medical Library Association Annual Conference

TITLE: Designing a Poster-to-Publication Campaign for Medical Residents

OBJECTIVE: To describe the development of a campaign to improve medical residents’ knowledge of the research and publication process while providing support in transforming poster presentations into peer-reviewed publications.

METHODS: Medical residents at a public research university complete poster presentation projects as part of the standard residency curriculum, but few go on to expand upon and publish this research in academic journals. This paper describes the development of a campaign intended to support residents as they expand poster research projects into publishable articles. A needs assessment will be developed to identify gaps …


Health Sciences Libraries: Supporting Public Libraries Supporting All Of Us, Leah Cordova, Alexandria Quesenberry, Hilary Jasmin Oct 2019

Health Sciences Libraries: Supporting Public Libraries Supporting All Of Us, Leah Cordova, Alexandria Quesenberry, Hilary Jasmin

Southern Chapter/Medical Library Association Annual Conference

Title: Health Sciences Libraries: Supporting Public Libraries Supporting All of Us

Objective: Public libraries are known for being community-centered institutions providing equitable access to information and resources, playing an important role in improving individuals' access to health-related information. This project aimed to examine the perceived role and current practices of inner-city public librarians in delivering health-related information to members of their community.

Methods: An online survey was created using Qualtrics and distributed to branch libraries within a single library system serving diverse socioeconomic and demographic groups. The survey consisted of eighteen multiple choice and open-ended questions. Information was collected around …


Health Information Technology (Hit) Experiences Of The Person With Heart Failure: A Descriptive Interpretive Phenomenological Mini Study, Pamela S. Kallmerten Oct 2019

Health Information Technology (Hit) Experiences Of The Person With Heart Failure: A Descriptive Interpretive Phenomenological Mini Study, Pamela S. Kallmerten

2019 Sigma Region 15 Nursing Research Symposium

Sufficient research has been conducted to explore the lived experience of the person with heart failure. Gap in the knowledge is in regards to the lived experience of those with repeated hospitalizations and their use of health information technology (HIT) which can support self management. Purpose of this project is to describe the lived experience of using HIT by the person with heart failure who has been readmitted to the hospital within the previous six months.


Identifying Pragmatic Aspects For Succession Planning Needs: Conversations With Nurse Managers And Nurse Directors, Tammy Whitney Oct 2019

Identifying Pragmatic Aspects For Succession Planning Needs: Conversations With Nurse Managers And Nurse Directors, Tammy Whitney

2019 Sigma Region 15 Nursing Research Symposium

A severe nursing shortage is predicted by 2020, and just as alarming is the likely shortage of nurse managers and nurse directors. Effective succession planning for nurse leaders affects recruitment and retention, patient outcomes, staff engagement, and finances. Preparing successors for leadership is imperative for hospitals to surmount challenges today and in the future. The focus of this project was to discover first hand challenges of succession planning and opportunities for developments.


New Graduate Orientation Evaluation: Are There Any Best Practices Out There?”, Jennifer Laflamme Oct 2019

New Graduate Orientation Evaluation: Are There Any Best Practices Out There?”, Jennifer Laflamme

2019 Sigma Region 15 Nursing Research Symposium

In the current nursing shortage, a time when healthcare needs to get innovative with hiring and retaining new graduate nurses, orientation can be a factor in a new graduate’s decision to leave their place of employment. Efficient, cost effective, and safe orientations with clear expectations are necessary, including orientation evaluation. There is, however, little guidance in the literature on best practices for completing an orientation evaluation. Although scarce, innovations and evidence do exist, as do research opportunities, and those are discussed during this presentation. The purpose of this project was to describe, based on the literature, current evidence that seeks …


Examining The Perceptions Of Nursing Students And Preceptors Using The Dedicated Education Unit Model For Clinical Experience, Sandra Benton, Betsy Corrigan, Deborah Eremita Oct 2019

Examining The Perceptions Of Nursing Students And Preceptors Using The Dedicated Education Unit Model For Clinical Experience, Sandra Benton, Betsy Corrigan, Deborah Eremita

2019 Sigma Region 15 Nursing Research Symposium

Presentation describing research investigating the effect on students’ perception of clinical competency level and self confidence when the Dedicated Education Unit (DEU) model, traditional 8 hour clinical or traditional 12 hour clinical rotations are used for the clinical experience, and preceptors’ perception of benefits, support, and commitment to the preceptors’ role when participating as a DEU preceptor.


Use Of Multi Patient Simulations To Facilitate Transition Of New Graduate Nurses, Valerie Herbert, Kaitlin Robinson, Patricia Poirier Oct 2019

Use Of Multi Patient Simulations To Facilitate Transition Of New Graduate Nurses, Valerie Herbert, Kaitlin Robinson, Patricia Poirier

2019 Sigma Region 15 Nursing Research Symposium

Description of research project investigating the use of multi patient simulations to identify competencies, evaluate performance, and determine effect on self-confidence and preparedness for practice.

Research Questions:

  1. What are the critical student behaviors identified by the Creighton Competency Evaluation Instrument (C CEI © ) that are needed to achieve competency in a senior level transition to practice nursing course?
  2. Does the use of a detailed evaluation tool in simulation experiences increase interrater objectivity and reliability in assessment of behaviors required of nursing students?
  3. In senior nursing student nurses preparing to graduate, what is the effect of the simulation lab on …


Full Program: A Call For Research That Begs To Be Translated Into Practice, Sigma Region 15 Oct 2019

Full Program: A Call For Research That Begs To Be Translated Into Practice, Sigma Region 15

2019 Sigma Region 15 Nursing Research Symposium

Full program for 2019 Sigma Region 15 Nursing Research Symposium: A Call for Research that Begs to Be Translated into Practice.


Hepatitis B Virus Screening And Vaccination, Uwaezu J. Umeh Oct 2019

Hepatitis B Virus Screening And Vaccination, Uwaezu J. Umeh

DNP Qualifying Manuscripts

Abstract

Hepatitis B is a virus that mostly affects the liver, it could be asymptomatic and if left untreated or undetected, could lead to liver cancer, cirrhosis or even death. When Hepatitis B virus enters the body, it could be detected as early as 30 days post exposure and if it persists, may develop into a chronic condition. Chronic hepatitis B is the persistence of hepatitis B surface antigen for six months or more. It is a global health problem in which an estimated 2 billion people worldwide are infected and with about 2.2 million people infected in the United …


A Collaborative Partnership Project: Serving The Vulnerable And Educating Tomorrow’S Healthcare Professionals, Leslie J. Knight, Trisha A. Mason Oct 2019

A Collaborative Partnership Project: Serving The Vulnerable And Educating Tomorrow’S Healthcare Professionals, Leslie J. Knight, Trisha A. Mason

Service Learning Faculty Posters

The University of New England (UNE), Portland Public Library (PPL) and Maine Medical Center (MMC) came together to promote health awareness and provide resources for underserved community members. The project exemplifies the collaborative leadership of three community stakeholders in support of a vulnerable population while teaching leadership to healthcare profession students.Success of the project meant merging each stakeholder’s goals: UNE Westbrook College of Health Professions’ goal was to provide health profession students with opportunities to work with and learn from vulnerable populations and instill a lifelong commitment to service; Portland Public Library’s goal was, as a civic and cultural center, …


Increased Interactions And Engulfment Of Dendrites By Microglia Precede Purkinje Cell Degeneration In A Mouse Model Of Niemann Pick Type-C., Larisa Kavetsky, Kayla K Green, Bridget R Boyle, Fawad A K Yousufzai, Zachary M Padron, Sierra E Melli, Victoria L Kuhnel, Harriet M Jackson, Rosa E Blanco, Gareth R Howell, Ileana Soto Reyes Oct 2019

Increased Interactions And Engulfment Of Dendrites By Microglia Precede Purkinje Cell Degeneration In A Mouse Model Of Niemann Pick Type-C., Larisa Kavetsky, Kayla K Green, Bridget R Boyle, Fawad A K Yousufzai, Zachary M Padron, Sierra E Melli, Victoria L Kuhnel, Harriet M Jackson, Rosa E Blanco, Gareth R Howell, Ileana Soto Reyes

College of Science & Mathematics Departmental Research

Niemann Pick Type-C disease (NPC) is an inherited lysosomal storage disease (LSD) caused by pathogenic variants in the Npc1 or Npc2 genes that lead to the accumulation of cholesterol and lipids in lysosomes. NPC1 deficiency causes neurodegeneration, dementia and early death. Cerebellar Purkinje cells (PCs) are particularly hypersensitive to NPC1 deficiency and degenerate earlier than other neurons in the brain. Activation of microglia is an important contributor to PCs degeneration in NPC. However, the mechanisms by which activated microglia promote PCs degeneration in NPC are not completely understood. Here, we are demonstrating that in the Npc1nmf164 mouse cerebellum, microglia …


Resident Experience Discussion (Red): Resident-Led Discussion Groups To Promote Resilience, Timothy Kuchera, Colin J. Thomas, Candace L. Haddox, Hannah C. Nordhues, Deanne T. Kashiwagi, Alan Kubey Oct 2019

Resident Experience Discussion (Red): Resident-Led Discussion Groups To Promote Resilience, Timothy Kuchera, Colin J. Thomas, Candace L. Haddox, Hannah C. Nordhues, Deanne T. Kashiwagi, Alan Kubey

Department of Medicine Posters

We sought to promote resident wellness through a resident-initiated-and-run discussion forum outside the formal residency structure


Online Learning & Medical Education … You Can Do It!, Carmin Bermudez, Med, Joanna Chan, Md Oct 2019

Online Learning & Medical Education … You Can Do It!, Carmin Bermudez, Med, Joanna Chan, Md

Department of Pathology, Anatomy, and Cell Biology Posters

  • Engaging learners and building community online improves learning and motivation for learners
  • Faculty presence incorporates integral feedback and increases student success
  • The CTL provides ongoing training and support, you are not alone!


Mindfulness Based Stress Reduction Increases Pathology Resident Self Wellness, Kaitlin Collura, Md, Phd, Joanna Chan, Md Oct 2019

Mindfulness Based Stress Reduction Increases Pathology Resident Self Wellness, Kaitlin Collura, Md, Phd, Joanna Chan, Md

Department of Pathology, Anatomy, and Cell Biology Posters

Stress during medical residency is a common, complex issue influenced by time demands, level of social support, and environmental factors. Increased stress levels can lead to resident burnout, and may contribute to the high rates of depression and suicide seen among physicians. In 2015, the ACGME began a campaign to promote resident wellness by calling on programs to implement strategies to develop resiliency, identify problems, and promote wellbeing. Mindfulness based stress reduction (MBSR) strategies have been shown to decrease burnout, improve mood, and increase compassion in healthcare providers. We implemented a wellness retreat to educate residents on the principles of …


Wellness Initiative Program And Effect On Pathology Resident Burnout Rate, Kaitlin Collura, Md, Phd, Michelle Nagurney, Md, Joanna Chan, Md Oct 2019

Wellness Initiative Program And Effect On Pathology Resident Burnout Rate, Kaitlin Collura, Md, Phd, Michelle Nagurney, Md, Joanna Chan, Md

Department of Pathology, Anatomy, and Cell Biology Posters

Increasing rates of physician burnout are reported across many medical specialties, including Pathology. In 2014, 52.5% of pathologists experienced symptoms of burnout compared to 37.6% in 2011. Suicide and depression rates in physicians are also higher than the average population. As a result, the ACGME began a campaign, in 2015, to foster resident wellness. The campaign calls for strategies to develop resiliency, identify problems, and promote well-being. While wellness initiatives may not change underlying mental illness, they may mitigate environmental factors that can exacerbate mental illness or suicidal behavior. Here we report results from a recently implemented resident wellness initiative …


Increased Interactions And Engulfment Of Dendrites By Microglia Precede Purkinje Cell Degeneration In A Mouse Model Of Niemann Pick Type-C., Larisa Kavetsky, Kayla K Green, Bridget R Boyle, Fawad A K Yousufzai, Zachary M Padron, Sierra E Melli, Victoria L Kuhnel, Harriet M. Jackson, Rosa E Blanco, Gareth R Howell, Ileana Soto Oct 2019

Increased Interactions And Engulfment Of Dendrites By Microglia Precede Purkinje Cell Degeneration In A Mouse Model Of Niemann Pick Type-C., Larisa Kavetsky, Kayla K Green, Bridget R Boyle, Fawad A K Yousufzai, Zachary M Padron, Sierra E Melli, Victoria L Kuhnel, Harriet M. Jackson, Rosa E Blanco, Gareth R Howell, Ileana Soto

Faculty Research 2019

Niemann Pick Type-C disease (NPC) is an inherited lysosomal storage disease (LSD) caused by pathogenic variants in the Npc1 or Npc2 genes that lead to the accumulation of cholesterol and lipids in lysosomes. NPC1 deficiency causes neurodegeneration, dementia and early death. Cerebellar Purkinje cells (PCs) are particularly hypersensitive to NPC1 deficiency and degenerate earlier than other neurons in the brain. Activation of microglia is an important contributor to PCs degeneration in NPC. However, the mechanisms by which activated microglia promote PCs degeneration in NPC are not completely understood. Here, we are demonstrating that in the Npc1nmf164 mouse cerebellum, microglia …


Réduire L’Exposition Des Travailleurs Aux Gaz, Odeurs, Poussières Et Agents Pathogènes Humains Présents Dans Les Bâtiments Porcins, Matthieu Girard, Caroline Duchaine, Stéphane Godbout, Ariane Lévesque, Valérie Létourneau, Stéphane P. Lemay Oct 2019

Réduire L’Exposition Des Travailleurs Aux Gaz, Odeurs, Poussières Et Agents Pathogènes Humains Présents Dans Les Bâtiments Porcins, Matthieu Girard, Caroline Duchaine, Stéphane Godbout, Ariane Lévesque, Valérie Létourneau, Stéphane P. Lemay

Rapports de recherche scientifique

Les éleveurs de porcs du Québec sont quotidiennement exposés à d’importantes quantités de gaz, d’odeurs, de poussières et de bioaérosols. Par conséquent, ils sont à risque de développer des problèmes respiratoires (ex. asthme) ainsi que des maladies infectieuses telles qu’une méningite à Streptococcus suis. Le risque de développer un problème de santé est lié au nombre d’heures passées à l’intérieur des bâtiments d’élevage ainsi qu’aux concentrations des différents contaminants. De plus, les travailleurs peuvent être en contact avec des bactéries résistantes aux antibiotiques soit des bactéries sélectionnées par l’emploi d’agents antimicrobiens utilisés lors de l’engraissement des animaux. Finalement, de …


A Computational Model For Recovery From Brain Injury, Wayne Wakeland Oct 2019

A Computational Model For Recovery From Brain Injury, Wayne Wakeland

Systems Science Friday Noon Seminar Series

A computational simulation model calculates recovery trajectories following traumatic brain injury (TBI). Prior publications include a multi-scale framework for studying concussion and a systems-level causal loop diagram (CLD) and discussion of feedback processes. The scope of the computational model goes beyond concussion to include all severities of TBI. A set of first order ordinary differential equations and their associated parameters determines recovery trajectories. While highly speculative, the model serves to demonstrate the potential utility of computational models in this context. Much more research will be needed to create a properly supported research model that could be used for clinical trial …