Medicine and Health Sciences Commons^™

Cangrelor Use In Patients Undergoing Percutaneous Coronary Intervention Or Neurointervention With Stent Placement In A Community Hospital, Radhan Gopalani, Jessica Justiz, Monica Tadros, Stephanie Palma, Andrea Marr-Peralto

All Publications

No abstract provided.

Advanced Practice Providers: How Do We Improve Their Organizational Engagement?, Molly Condit, Paula Hafeman

College of Nursing Faculty Research and Publications

Advanced practice providers (APPs) are integral members of the multidisciplinary health care team, providing access to high quality and cost-effective patient care. Despite the consistent increase in demand for APPs, these practitioners often lack role clarity, frequently resulting in poor job satisfaction and retention. Establishing an advanced practice provider council within organizations is a positive step in providing APPs with a platform for increasing their visibility, peer support, and decision-making power, thereby improving their engagement within the organization.

Efficacy Of Natural Family Planning Methods, Richard J. Fehring

College of Nursing Faculty Research and Publications

No abstract provided.

Bipolar Fresh Osteochondral Allograft Transplantation And Joint Reconstruction For Patellar And Trochlear Cartilage Defects, Omid Jalali, Zachary Vredenburgh, John Prodromo, Neilen Benvegnu, George Frederick Rick Hatch

Faculty, Staff and Students Publications

Patellar instability is a debilitating condition, and trauma due to the dislocations may severely damage the articular cartilage of the patellofemoral joint. The lack of healing capacity of cartilage makes treatment of such lesions challenging. In young patients, preservation of native bone and cartilage is a priority, and therefore arthroplasty procedures should be avoided even in relatively larger lesions. Fresh osteochondral allografting has been described for these difficult and complex cases, with recent studies showing promising results. In this surgical technique, we describe the use of bipolar osteochondral allografts of the patella and trochlea and patellofemoral joint reconstruction for large …

Gna11 Brain Somatic Pathogenic Variant In An Individual With Phacomatosis Pigmentovascularis, Joseph M Sliepka, Sarah C Mcgriff, Linda Z Rossetti, Peyman Bizargity, Haley Streff, Yi-Shan Lee, Hongzheng Dai, Satyamaanasa Polubothu, Grace Lee, Vicky Ren, Jill V Hunter, Daniel J Curry, Fernando Scaglia, Adekunle M Adesina, Irfan Ali, Veronica Kinsler, Lindsay C Burrage, Dana Marafi

Faculty, Staff and Students Publications

OBJECTIVE: To describe the findings of histopathology and genotyping studies in affected brain tissue from an individual with phacomatosis pigmentovascularis (PPV).

METHODS: A retrospective chart review of a 2-year 10-month-old male with a clinical diagnosis of PPV cesiomarmorata (or type V) was performed. Clinical features, brain imaging and histopathology findings, and genotyping studies in his affected brain tissue are summarized.

RESULTS: The proband had a clinically severe neurologic phenotype characterized by global developmental delay, generalized hypotonia, and recurrent episodes of cardiac asystole in the setting of status epilepticus. A somatic pathogenic variant in

CONCLUSIONS: The finding of this variant in …

Structural Basis Of Amino Acid Surveillance By Higher-Order Trna-Mrna Interactions, Shuang Li, Zhaoming Su, Jean Lehmann, Vassiliki Stamatopoulou, Nikoleta Giarimoglou, Frances E Henderson, Lixin Fan, Grigore D Pintilie, Kaiming Zhang, Muyuan Chen, Steven J Ludtke, Yun-Xing Wang, Constantinos Stathopoulos, Wah Chiu, Jinwei Zhang

Faculty, Staff and Students Publications

Amino acid availability in Gram-positive bacteria is monitored by T-box riboswitches. T-boxes directly bind tRNAs, assess their aminoacylation state, and regulate the transcription or translation of downstream genes to maintain nutritional homeostasis. Here, we report cocrystal and cryo-EM structures of Geobacillus kaustophilus and Bacillus subtilis T-box-tRNA complexes, detailing their multivalent, exquisitely selective interactions. The T-box forms a U-shaped molecular vise that clamps the tRNA, captures its 3' end using an elaborate 'discriminator' structure, and interrogates its aminoacylation state using a steric filter fashioned from a wobble base pair. In the absence of aminoacylation, T-boxes clutch tRNAs and form a continuously …

Results Of A Phase 1 Multicentre Investigation Of Dexmedetomidine Bolus And Infusion In Corrective Infant Cardiac Surgery, Athena F Zuppa, Susan C Nicolson, Nicole S Wilder, Juan C Ibla, Erin A Gottlieb, Kristin M Burns, Mario Stylianou, Felicia Trachtenberg, Hua Ni, Tera H Skeen, Dean B Andropoulos

Faculty, Staff and Students Publications

BACKGROUND: Dexmedetomidine (DEX) is increasingly used intraoperatively in infants undergoing cardiac surgery. This phase 1 multicentre study sought to: (i) determine the safety of DEX for cardiac surgery with cardiopulmonary bypass; (ii) determine the pharmacokinetics (PK) of DEX; (iii) create a PK model and dosing for steady-state DEX plasma levels; and (iv) validate the PK model and dosing.

METHODS: We included 122 neonates and infants (0-180 days) with D-transposition of the great arteries, ventricular septal defect, or tetralogy of Fallot. Dose escalation was used to generate NONMEM® PK modelling, and then validation was performed to achieve low (200-300 pg ml …

A Rewiring Model Of Intratumoral Interaction Networks., Mengmeng Sang, Shawn Rice, Libo Jiang, Xin Liu, Claudia Gragnoli, Chandra P. Belani, Rongling Wu

Division of Endocrinology, Diabetes and Metabolic Diseases Faculty Papers

Intratumoral heterogeneity (ITH) has been regarded as a key cause of the failure and resistance of cancer therapy, but how it behaves and functions remains unclear. Advances in single-cell analysis have facilitated the collection of a massive amount of data about genetic and molecular states of individual cancer cells, providing a fuel to dissect the mechanistic organization of ITH at the molecular, metabolic and positional level. Taking advantage of these data, we propose a computational model to rewire up a topological network of cell-cell interdependences and interactions that operate within a tumor mass. The model is grounded on the premise …

Selecting The Best Measure For Hospital-Acquired Deconditioning, Carmen E. Capo-Lugo, Erik H. Hoyer, Daniel Young

Integrated Health Sciences Faculty Research

No abstract provided.

The Anatomy Act Of 1832: The Story Of Bodysnatching, Dissections, And The Rise Of Anatomy, Rebecca Burrows

Tenor of Our Times

The Anatomy Act of 1832, a story of bodysnatching and dissections, changed the face of anatomy in 19th century Britain with its somewhat violent beginnings, controversial creation, and important ramifications towards medicine and society.

Effect Of Self-Regulated Learning For Improving Dietary Management And Quality Of Life In Patients With Type-2 Diabetes Mellitus At Dr. Ramelan Naval Hospital, Surabaya, Indonesia, Yayuk Estuningsih, Thinni Nurul Rochmah, Merryana Andriani, Trias Mahmudiono

Kesmas

Self-regulated learning is a process of learning how to manage and regulate oneself to obtain skills and knowledge without depending on others. It is expected that diabetes patients can manage their diabetes by themselves. This study aimed to analyze the effect of self-regulated learning-based educational intervention on quality of life for patients with type-2 diabetes mellitus (DM) at Dr. Ramelan Naval Hospital, Surabaya. This was a quasi-experimental study in the form of pretest and posttest with a control group design. A total of 20 patients with DM were randomly divided into intervention and control groups to undergo a 4-week intervention. …

Maternal Knowledge, Attitude, And Practices About Traditional Food Feeding With Stunting And Wasting Of Toddlers In Farmer Families, Betty Yosephin Simanjuntak, Miratul Haya, Desri Suryani, Ali Khomsan, Che An Ahmad

Kesmas

Traditional foods are foods consumed by a certain ethnic group in a specific region. The habit of consuming traditional foods is usually inherited by the family members, including toddlers, of a respective generation. The study aimed to determine relationship of maternal knowledge, attitude, and practices in traditional food feeding with stunting and wasting of toddlers in the farmer families of the Central Bengkulu District. This study employed a cross-sectional design with a sample of mothers with children aged 12–59 months. The sample included a total of 115 farmer families. Data on nutritional knowledge, attitude, practices about traditional food, sex of …

Overweight And Obesity Status With Dental Caries Among Children Aged 7–12 Years Old In Badung District, Bali 2018, Hariani Rafitha, Putri Bungsu Machmud, Ratna Djuwita, Dwi Gayatri, Fakhrana Ariani Ayub

Kesmas

Dental caries is an infectious disease that Dental is characterized by the dental damage resulting from microorganism products in carbohydrate fermentation. Dental caries and obesity in children are multifactorial diseases associated with eating habits and certain lifestyle factors. This study aimed to assess the association between overweightness, obesity, and dental caries among children aged 7–12 years in Badung district, Bali province in 2018. The total sample of 426 children and their mothers were recruited from all first to fifth elementary grade students in three schools selected by simple random sampling. The logistic regression analysis has demonstrated a significant association between …

Personal Exposure Of Traffic Policeman To Particulate Matter In Jakarta: Distribution Of Size, Chemical Composition, And Work Time, Doni Hikmat Ramdhan, Eka Fitriani Ahmad, Fitri Kurniasari, Zuly Prima Rizky, Hardy Atmajaya, Muhayatun Santoso

Kesmas

Particulate matter (PM) is an air pollutant that has an impact on public health, especially in an urban area. The objective of this study was to analyze the personal concentration of PM2.5 and its composition among police working in the roadside area in Jakarta. PM measurement has done to the policeman that controlled traffic on four near highway locations in Jakarta. Sioutas impactor, Leland Legacy personal pump, and quartz fiber filter were chosen to measure the fine particles. Each PM was measured for 8-hour period. PM concentration was analyzed by the gravimetric method while tracing element and black carbon in …

Users’ Perception Of The Hospital Information System In A Maternity Hospital In Lampung, Indonesia, Al Asyary, Arief Kurniawan Nur Prasetyo, Tris Eryando, Solvay Gerke

Kesmas

Hospital information systems (HIS) have been applied on a massive scale; however, user evaluation of their effectiveness, efficiency, and service quality improvements remain rare. This study aimed to describe the utility of information systems from the users’ point of view by using the Technology Acceptance Model (TAM) in a maternity hospital in Lampung, Indonesia. The study provided an overview of the features of the information system and the workflow of the user through this information system. Screenshots were taken by using Camtasia Studio 2.0 Trial Version application software for one day (two shifts) in the outpatient service. The HIS generally …

Knowledge, Attitude, Practices, And Health Beliefs Of Pregnant Women About Urinary Tract Infection And Its Associated Risk Factors: A Local Filipino Community Experience, Annalyn Navarro, Raphael Enrique Tiongco, Reynaldo Bundalian Jr.

Kesmas

Urinary tract infection (UTI) during pregnancy is assumed to be associated with increased maternal and fetal morbidity and mortality; hence, a proper assessment of knowledge and practices is crucial to formulate preventive strategies to ensure the health of both the mother and the baby. The study determined the knowledge, attitude, practices (KAP), and the beliefs of pregnant women about UTI based on the Health Belief Model. A survey questionnaire was used to gather data from pregnant women with and without UTI. The association of the pregnant women’s sociodemographic characteristics with their KAP and health beliefs was determined using Pearson’s chi-square …

Midwife’S Role In The Mother-To-Child Transmission Prevention Program In Primary Health Care In Yogyakarta, Niken Meilani, Nanik Setiyawati, Sammy Onyapidi Barasa

Kesmas

Curing and eradicating Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndrome (AIDS) are to the core principles of the United Nations’ Sustainable Development Goals (SDGs). The incidence of HIV in the world remains high. Although midwives play a pivotal role in PMTCT implementation, the factors associated with midwives’ role in its implementation are not well understood. The aim of this study was to determine factors associated with midwives’ role in implementation of PMTCT. This study used a cross-sectional design. The subjects were 80 midwives at 14 primary health care in Yogyakarta City, Indonesia. The study was conducted from April to August 2017. …

Sexual Dysfunction Among Women With Diabetes In A Primary Health Care At Semarang, Central Java Province, Indonesia, Lintang Dian Saraswati, Ari Udiyono, Dian Sutrisni, Muh Fauzi

Kesmas

Sexual dysfunction is associated with pain during sexual intercourse. Diabetes mellitus (DM) has been reported to be one of the causal factors for sexual dysfunction in women. This cross-sectional study was conducted to describe the status of sexual dysfunction in women with DM in the Tlogosari Kulon Primary Health Care, Semarang, Indonesia, in March 2017. A total of 103 women with DM attending the health center participated in this study. Data were collected using a questionnaire-guided interview and through measurements (blood pressure and random blood glucose test). Results showed that 74.8% of women with DM had sexual dysfunction. The proportion …

We've Got You Covered, Meghan Cooper

Graduate Scholarly Works

White paper for the Health Promotion and Wellness department and the Condom Concierge program.

Risiko Penyakit Kardiovaskuler Pada Peserta Program Pengelolaan Penyakit Kronis (Prolanis) Di Puskesmas Kota Bima: Korelasinya Dengan Ankle Brachial Index Dan Obesitas, Martiningsih Martiningsih, Abdul Haris

Jurnal Keperawatan Indonesia

Risk of Cardiovascular Diseaseat Chronic Disease Management Program Participants in The Community Health Centers of Bima Town:The Correlation with Ankle Brachial Index and Obesity. Cardiovascular disease(CVD)is a disease caused by impaired heart and blood vessel function, which can be prevented,especiallyin risk groupsthat can berisk assessedusing the FraminghamRisk Score (FRS). The purpose of this study was to analyze the risk of CVD and the correlation with ABI and obesity in Prolanis participants at Bima City.Data collectionwas done byusing the instrument FRSandmeasuring systolic blood pressure, body mass index, arm circumference,and waist circumference.This study was a descriptive-analytic study with a cross-sectional design. The …

The Effect Of Monitoring Education On Menstrual Health Awareness Among College Students In Banten, Dora Samaria, Theresia Theresia, Doralita Doralita

Jurnal Keperawatan Indonesia

Previous studies have shown that female college students have a low awareness of menstrual health. This situation must be resolved to prevent negative effects on their reproductive health. The objective of this study was to identify the effect of menstrual flow monitoring education on menstrual health awareness using lectures, demonstrations, and exercises. The researcher used menstrual flow charts and menstrual calendars as learning media. This study used a quasi- experimental design with only one group pretest and posttest. The sample was made up of 117 female college students from the Economic Education Study Program at University X; the individuals were …

The Increase Of Hiv-1 Infection, Neurocognitive Impairment, And Type 2 Diabetes In The Rio Grande Valley, Roberto De La Garza, Hansapani Rodrigo, Francisco Fernandez, Upal Roy

Health & Biomedical Sciences Faculty Publications

The Human Immunodeficiency Virus (HIV-1) infection remains a persistent predicament for the State of Texas, ranking seventh among the most documented HIV cases in the United States. In this regard, the Rio Grande Valley (RGV) in South Texas is considered as one of the least investigated areas of the state with respect to HIV infection and HIV associated comorbidities. Considering the 115% increase in average HIV incidence rates per 100,000 within the RGV from 2007-2015, it is worth characterizing this population with respect to their HIV-1 infection, HIV-1 Associated Neurocognitive Disorders (HAND), and the association of treatment with combined antiretroviral …

Studi Fenomenologi: Mekanisme Koping Perempuan Yang Belum Mempunyai Keturunan Ditinjau Dari Aspek Budaya Minangkabau, Rahmaniza Rahmaniza, Ni Made Riasmini, Netrida Netrida

Jurnal Keperawatan Indonesia

Phenomenology Study: Coping Mechanism of Women No Heredity Viewed by Minangkabau Culture.The Minangkabau tribe adheresto the matrilineal kinship system. Based on this system, when a woman suffers infertility, so it means the family has not the next generation, and the line of descent will cut off. This condition makes the women need to have a coping mechanism to avoid psychology problems, including depression, anxiety, stress, neglected, discrimination, under pressure to divorce, and perceive abused. The study aimed to explore the coping mechanism of infertility women in the context of Minangkabau culture. This phenomenology study applied an in-depth interview,which involved ten …

Pengaruh Aplikasi Model "Simbol Andi" Terhadap Pengetahuan, Sikap Dan Keterampilan Anak Usia Sekolah Dengan Risiko Cedera Di Kota Depok, Ressa Andriyani Utami, Agus Setiawan, Poppy Fitriyani

Jurnal Keperawatan Indonesia

The influence of "Simbol Andi" Model Application of Knowledge, Attitude, and Skills of School Ages with Injury Risk in Depok City.Injuries caused5.8 million deaths worldwide and 16% of injury cases causeddisability. Behavioralof school-age children that include knowledge, attitudes,and skills affect the incidence of injury in school-aged children.“Sandi”Symbolic Modellingis injury prevention using video animationfor injury prevention. This study aimedto an analysisofthe application of Model Sandi (Simbol Andi) in the prevention of injury to the community. The design of this study was a quasi-experimentpreand posttestwithout control group. A total sample 136 school-agedchildrenat 11 and12 years oldinvolved in this study. The sampling method …

Peningkatan Melek Kesehatan Perawat Melalui Pengarahan Kepala Ruang Menggunakan Program Internalisasi Hasil Evaluasi Belajar Perawat, Munezarah Munezarah, Hanny Handiyani, Tuti Nuraini

Jurnal Keperawatan Indonesia

Increasing Nurses’ Health Literacy Using Direction with Internalization of Nurses Study Evaluation Result “Program InternalisasiHasilBelajarPerawat(PIN Hebat)”. Health literacy is very important for nurses’ safety. The low of nurses’health literacy is one of the factors in increasing injury reports of needlestick injuryin hospitals. The efforts to optimize nurse’s health literacy can be done through an innovative direction that is internalization of nurses study evaluation result “program internalisasihasilevaluasibelajarperawat (PinHebat)”. The aim of this research was examining impact of Pin Hebattoward nurse health literacy. Research method was pre-experiment with pretest and posttest control group approach. The sampling technic was consecutive sampling, with 88 …

The Impact Of Vegetarian Diets And Body Mass Index On Hypertension, Tri Mariha, Wiwin Wiarsih

Jurnal Keperawatan Indonesia

A vegetarian diet is believed to prevent hypertension. This study aims to identify the impact of vegetarian diets, including fat, salt, potassium, and body mass index (BMI), on hypertension. Data was taken by systematic random sampling method from 173 vegetarians and analyzed using chi-square. The result showed that there is no significant association between the intake of fat, sodium, and potassium with hypertension in vegetarians (p> 0.05). However, there is a significant relationship between BMI with the incidence of hypertension (p= 0.025), where overweight res-pondents are 3.837 more likely to have hypertension (OR 3.837; 95% CI= 1,256–11,721). It implies that …

Pemberian Posisi (Positioning) Dan Nesting Pada Bayi Prematur: Evaluasi Implementasi Perawatan Di Neonatal Intensive Care Unit (Nicu), Defi Efendi, Dian Sari, Yanti Riyantini, Novardian Novardian, Dian Anggur, Pipit Lestari

Jurnal Keperawatan Indonesia

Pemberian posisi yang salah dapat meningkatkan risiko morbiditas dan mortalitas. Artikel ini bertujuan untuk menggali pemberian posisi (positioning) dan nesting pada bayi prematur di NICU. Penelitian ini berupa studi literatur tahun 2007- 2017, serta pengalaman penulis dalam aplikasi pemberian posisi dan nest di dua rumah sakit rujukan nasional dalam lima tahun terakhir. Hasil studi ini menunjukkan beberapa posisi yang dapat diberikan pada bayi prematur di antaranya adalah posisi supinasi, lateral kiri, lateral kanan, pronasi, dan quarter/semi pronasi. Posisi pronasi dan kuarter/semi pronasi direkomendasikan untuk bayi prematur dengan Respiratory Distress Syndrome (RDS). Posisi lateral kanan direkomendasikan untuk bayi prematur dengan Gastroesofageal …

Medication Beliefs In Patients Following Percutaneous Coronary Intervention: A Cross-Sectional Study, Prima Agustia Nova, Ching-Huey Chen

Jurnal Keperawatan Indonesia

Patients post percutaneous coronary intervention need to take medication for their health. Beliefs about medication influence patients’ adherence in taking their medication regimens. Therefore, the study aimed to identify medication beliefs in patients following percutaneous coronary intervention in Indonesia. This research used a cross-sectional study with the convenience sampling method. A total of 132 adult patients following Percutaneous Coronary Intervention participated in this study. This study used The Beliefs about Medicines Questionnaire to identify patients’ beliefs about medication. The majority of respondents were male (85.6%) with a mean age of 60 years. Beliefs about general overuse were found to be …

Combined Modality Therapies For High-Risk Prostate Cancer: Narrative Review Of Current Understanding And New Directions., Benjamin A. Greenberger, Victor E. Chen, Robert B. Den

Department of Radiation Oncology Faculty Papers

Despite the many prospective randomized trials that have been available in the past decade regarding the optimization of radiation, hormonal, and surgical therapies for high-risk prostate cancer (PCa), many questions remain. There is currently a lack of level I evidence regarding the relative efficacy of radical prostatectomy (RP) followed by adjuvant radiation compared to radiation therapy (RT) combined with androgen deprivation therapy (ADT) for high-risk PCa. Current retrospective series have also described an improvement in biochemical outcomes and PCa-specific mortality through the use of augmented radiation strategies incorporating brachytherapy. The relative efficacy of modern augmented RT compared to RP is …

Drug Interactions With Antimalarial Medications In Older Travelers: A Clinical Guide, Jelena Lewis, Tania Gregorian, Ivan Portillo, Jeff Goad

Pharmacy Faculty Articles and Research

Increasingly older adults are traveling to international destinations with malaria as a present risk. Surveillance systems indicate that older adults are more likely to suffer severe complications from malaria. The role of health care providers in selecting an appropriate medication for chemoprophylaxis or treatment of malaria in adults becomes more difficult as older adults undergo physiologic changes that alter the pharmacokinetic and pharmacodynamic nature of medications potentially causing increased drug interactions, adverse events, and altered drug action. A comprehensive literature search from 1970 to present, with a focus on the last 10 years, was conducted on drug interactions, pharmacokinetic and …