Medicine and Health Sciences Commons^™

Maternal Characteristics And Outcomes Affected By Hypothyroidism During Pregnancy (Maternal Hypothyroidism On Pregnancy Outcomes, Mhpo-1), Zareen Kiran, Aisha Sheikh, Sarwar Malik, Areeba Meraj, Maha Masood, Safana Ismail, Owais Rashid, Quratulain Shaikh, Numan Majeed, Lumaan Sheikh, Najmul Islam

Section of Diabetes, Endocrinology and Metabolism

Background: Hypothyroidism in pregnancy is an arena of ongoing research, with international conflicts regarding screening, management, and outcomes. Various studies have described the outcomes depending on geographical and international diagnostic criteria. No study has been conducted in this regard from the region of Pakistan. Therefore, we aim to report the clinical features and maternal outcomes of hypothyroid pregnancies and compare the maternal outcomes between uncontrolled and controlled TSH levels in the preconception as well as the gestational period.
Methods: We conducted a cross-sectional retrospective study on 718 cases in the Aga Khan University Hospital after ethical approval. We collected information …

Réadaptation Au Travail Chez Les 45 Ans Et Plus Dans Le Secteur De La Santé Et Des Services Sociaux, Carl-Ardy Dubois, Kathleen Bentein, Alain Marchand

Rapports de recherche scientifique

Au Québec, les 45 ans et plus représentent une part croissante de la main-d'œuvre du secteur de la santé et des services sociaux. Pour assurer l’équilibre nécessaire entre la demande croissante de services de santé et l’offre de main-d’œuvre dans ce contexte de changement sociodémographique, les organisations du secteur font face au défi d’optimiser la participation au travail des plus âgés. Cela exige non seulement la prise en charge efficace des situations incapacitantes au travail chez les 45 ans et plus, mais aussi la prévention de ce type de lésions et le maintien ou la réinsertion en emploi de ceux …

A Dual Inhibitor Of The Proteasome Catalytic Subunits Lmp2 And Y Attenuates Disease Progression In Mouse Models Of Alzheimer's Disease, In Jun Yeo, Min Jae Lee, Ahruem Baek, Zachary Miller, Deepak Bhattarai, Yu Mi Baek, Hyun Jung Jeong, Yun Kyung Kim, Dong-Eun Kim, Jin Tae Hong, Kyung Bo Kim

Pharmaceutical Sciences Faculty Publications

The immunoproteasome (iP) is a variant of the constitutive proteasome (cP) that is abundantly expressed in immune cells which can also be induced in somatic cells by cytokines such as TNF-α or IFN-γ. Accumulating evidence support that the iP is closely linked to multiple facets of inflammatory response, eventually leading to the development of several iP inhibitors as potential therapeutic agents for autoimmune diseases. Recent studies also found that the iP is upregulated in reactive glial cells surrounding amyloid β (Aβ) deposits in brains of Alzheimer's disease (AD) patients, but the role it plays in the pathogenesis of AD remains …

Sepsis Screening Tool Increased The Usage Of Sepsis Order Set, Raweewan Liengsawangwong

Applied Research Projects

Introduction: The sepsis screening tool was launched to improve the usage of the sepsis order set.

Objectives: The purposes of this study were to determine whether the sepsis screening tool increased the usage of sepsis order set and whether the tool improved the primary outcomes. This study assessed the association between using sepsis order set and the compliance of the SEP-1 measure (represented by achieving total perfect care), and the primary outcomes. Furthermore, this study assessed association between the compliance with SEP-1 and the primary outcomes. The primary outcomes were a) time zero to antibiotics, b) inpatient length of stay, …

Health Status And Adults Willingness To Encounter A Provider By Telehealth, Jacqueline Perry

Applied Research Projects

Telehealth has proven to be a growing sector providing on-demand health services for consumers. A long history of development and refinement precede what we now know as telehealth technology. Access to telehealth technology has become widely available changing the landscape of healthcare. However, does that mean that consumers desire to use the technology? How does a factor such as health status play a role in the consumers’ willingness to encounter a provider using telehealth as the method for delivery of care? This research project aims to compare self-selected health status to consumers’ willingness to engage with telehealth services.

Assessing Bilingual Children With A Language Disorder, Ana Franco, Tricia Larkin, Ann Beck

Graduate Independent Studies - Communication Sciences and Disorders

The population in the United States is rapidly diversifying, and it is estimated that 4.9 million English-Language Learning (ELL) students are currently in the United States (National Center for Education Statistics, 2019). ELL students come from diverse linguistic backgrounds and have varying proficiencies in English and their native language. The linguistic and cultural differences bilingual ELL students present when they attend public schools have created challenges for the current assessment and treatment services available for those bilingual children with communication disorders. Speech-language pathologists (SLPs) are required to assess bilingual children suspected of having a language disorder, one of the most …

Effects Of Short-Term Study Abroad On Mindset, Anya Rowe, Heidi M. Harbers, Amy L. Yacucci

Graduate Independent Studies - Communication Sciences and Disorders

This review of the literature will address the effects of mindset, the effects of studying abroad, and the relationship between the two. Three research studies will be reviewed that explore outside factors and their effect on mindset, as well as how mindset impacts academic achievement. Seven additional research studies will examine the different types of study abroad experiences and their impact on student learning. A comparison between the effects of short-term and long-term study abroad will also be explored.

A Resource Manual For Kindergarten Teachers Of Phonetic Components Of Sounds, Katrisha Thomas, Heidi Harbers, Tricia Larkin

Graduate Independent Studies - Communication Sciences and Disorders

This literature review will present studies concerning the roles of the teacher and SLP within the school system, effective collaboration between general education teachers and SLPs, and evidence-based intervention models. An exploration of CCSS will outline what teachers are expected to teach at the kindergarten level. Next, the roles and responsibilities of the SLP from the American Speech-Language and Hearing Association (ASHA) will be reviewed to define what SLPs are expected to do within schools. Then, four articles will be reviewed to explain how teachers are missing an understanding of basic elements of the English Language necessary for effective instruction …

Long-Term Effects Of A Short-Term Study Abroad On Mindset, Madasyn Hofstedt, Heidi Harbers, Amy Yacucci

Graduate Independent Studies - Communication Sciences and Disorders

This literature review will examine 10 studies. The first section will discuss one study regarding common personality traits that practicing SLPs and SLP graduate students possess. The next section will review four studies about studying abroad. The final section will summarize four studies about the impact of mindset on life experiences and one study on how a growth mindset may potentially affect a study abroad experience.

The Role Of Executive Function Skills For College-Age Students, Brooke Ahrens, Margaret Lee, Carlee Zweibruck, Justine Tumanan, Tricia Larkin M.S. Ccc-Slp/L, Ann Beck Ph.D.

Graduate Independent Studies - Communication Sciences and Disorders

This paper is a review of executive function skills and the role of these skills in college students. Executive functioning allows individuals to process their surroundings and manage oneself in order to successfully complete a task. During college, students are attempting to balance various aspects of their lives. Effective use of executive functioning can allow a college student to be successful across all areas of their life. However, when a breakdown in executive functioning occurs, students may have difficulty achieving goals and balancing their demanding lives. These students may benefit from speech language therapy services. This literature review brings together …

Caregiver Strategies For Communication In Children With Autism In Spanish-Speaking, Developing Countries, Melissa K. Jenkins B.S., Emily K. Smith B.S., Jennifer Friberg, Tricia Larkin

Graduate Independent Studies - Communication Sciences and Disorders

The literature review provides current and relevant information for speech-language pathologists (SLPs) who service families with a child with autism (CWA) in Spanish-speaking, developing (SSD) countries. This review gives an overview of autism spectrum disorder (ASD) as it relates to language and language development and SLP scope of practice in the U.S. as it relates to ASD. Applicable evidenced-based strategies will be given to help SLPs provide family education to increase functional communication with their CWA. To be sensitive to cultural differences in SSD countries, interaction styles and customs will be defined and interviews from families and SLPs in SSD …

Exploring The Use Of The Bimanual Arm Trainer For Improving Upper Extremity Motor Function In Stroke Patients., Manuel G. Wilfred

Seton Hall University Dissertations and Theses (ETDs)

Background and purpose

There are few evidence-based treatment options to address recovery in patients with severe upper extremity impairment post-stroke. Although robotic treatment options have been widely explored with variable outcomes, the contribution of bimanual training to improve upper extremity control and coordination has not yet been fully explored. To date, the mirrored motion Bimanual Arm Trainer (BAT) has not specifically been investigated for its effectiveness in stroke patients. This study explored the usefulness of the bimanual arm trainer in improving upper extremity function in stroke patients with severe deficits and its impact on quality of life.

Methods

Twenty-three patients …

Effectiveness Of A Structured Online Prebriefing Activity On Prelicensure Students’ Clinical Judgment, Elizabeth M. Delavan

Nursing Theses and Dissertations

Significance of the Problem: Today’s healthcare environment requires new nurses to have strong clinical judgment skills upon entry to practice. Contributing to this problem are the challenges faced by prelicensure nursing programs that include faculty shortages and the decreasing availability of clinical spaces. Simulation activities offer hands-on clinical learning opportunities in the place of traditional clinical experiences. However, simulation labs are costly to develop and maintain, which impacts student learning opportunities. Prebriefing, an understudied area of simulation, provides educators with another clinical exercise to facilitate students’ growth in clinical judgment.

Objective: The purpose of this study was to explore the …

Assessing Knowledge And Perspectives Of Pediatric Nurse Practitioners Students After Receiving Trauma Informed Care Training, Laura Roettger, Phd, Crnp, Jane Tobias, Dnp, Crnp

College of Nursing Posters

PNP students showed improved understanding and comfort level in caring and managing children exposed to adverse childhood experiences following two TIC learning sessions.

Future Implications

• TIC education should be integrated into curriculum.
• Interprofessional collaboration among students improves knowledge base and understanding of TIC

Health & Kinesiology News, Georgia Southern University

Health Sciences & Kinesiology: News & Publications (2015-2023)

• Department Hosts NSCA Event

Safety Of Endoscopy And Its Outcome In Pregnancy, Lubna Kamani, Muhammad S. Achakzai, Faisal Wasim Ismail, Farhana Kayani

Section of Gastroenterology

Objective: Gastrointestinal (GI) endoscopy is an important tool for diagnosis and treatment of GI diseases. However, when endoscopy is indicated during pregnancy, concerns about its safety for mother and fetus often arise. Our objective was to evaluate the safety and efficacy of endoscopic procedures in pregnant patients along with maternal and fetal outcomes.
Methods: This study was conducted at the Aga Khan University Hospital after Ethics review committee approval. It was a retrospective study and medical records of all pregnant patients who underwent endoscopy during pregnancy from January 2000 to January 2014 were analyzed. Data regarding the indications and type …

Maternal Healthcare Services Use In Mwanza Region, Tanzania: A Cross-Sectional Baseline Survey, James Orwa, Michaela Mantel, Micheal Mugerwa,, Sharon Brownie, Eunice Pallangyo, Loveluck Mwasha, Kahabi Isangula, Leonard Subi, Secilia Mrema, Grace Edwards, David Siso, Edna Selestine, Tumbwene Mwansisya, Columba Mbekenga, Marleen Temmerman

Population Health, East Africa

Background: Improving maternal health by reducing maternal mortality/morbidity relates to Goal 3 of the Sustainable Development Goals. Achieving this goal is supported by antenatal care (ANC), health facility delivery, and postpartum care. This study aimed to understand levels of use and correlates of uptake of maternal healthcare services among women of reproductive age (15–49 years) in Mwanza Region, Tanzania.

Methods: A cross-sectional multi-stage sampling household survey was conducted to obtain data from 1476 households in six districts of Mwanza Region. Data for the 409 women who delivered in the 2 years before the survey were analyzed for three outcomes: four …

Sympathetic Nervous System Reactivity In Women Following Preeclamptic Pregnancies, Nina Stachenfeld, Charlotte Usseleman, Cheryl Leone, Michael Paidas

Yale Day of Data

Women who have had preeclamptic pregnancies are at risk for life-long cardiovascular disease. However, the factors contributing to this risk have yet to be established. Sympathetic nervous system dysregulation has been proposed to contribute to cardiovascular dysfunction during preeclamptic pregnancies. Therefore, we examined muscle sympathetic nerve activity (MSNA) at baseline and during a chemoreflex stimulus in women 6-24 months postpartum following a preeclamptic pregnancy (PE; n=6, age 28±2 y, BMI 27±3 kg/m2, 17±4 months postpartum). We hypothesized that MSNA responses to apnea would be greater in PE relative to control subjects, that is, women 6-24 months following a healthy pregnancy …

A Twitter-Based Network Analysis Of Brain Tumor Social Media, Josemari T. Feliciano

Yale Day of Data

The Brain Tumor Social Media (#BTSM) Twitter hashtag was founded in February 2012 as a disease-specific hashtag for brain tumor patients. To understand #BTSM’s role as a patient support system we describe user descriptors, growth, interaction, and content sharing.

Saving Software And Using Emulation To Reproduce Computationally Dependent Research Results, Euan Cochrane, Limor Peer, Ethan Gates, Seth Anderson

Yale Day of Data

Using digital data necessarily involves software. How do institutions think about software in the context of the long-term usability of their data assets? How do they address usability challenges uniquely posed by software such as, license restrictions, legacy software, code rot, and dependencies? These questions are germane to the agenda set forth by the FAIR principles. At Yale University, a team in the Library is looking into the application of a novel approach to emulation as a potential solution. In this presentation, we will outline the work of the Emulation as a Service Infrastructure (EaaSI) program, discuss our plans for …

The Hiv Vaccine: Learning From Failure And Building On Success, Lindsey Mcclish, Kimberly Gathers, Katie Salay, Lisa Vranekovic, Kristin Seaman, Kelly M. Shields

Pharmacy and Wellness Review

An effective vaccine for acquired immune deficiency syndrome (AIDS) has eluded researchers since the identification of the HIV virus. There are many challenges in developing an effective HIV vaccine, including the lack of knowledge regarding the immune response to the virus and its diverse nature. Ethical concerns further complicate research. A recent phase III trial was performed in Thailand and showed that a significant reduction in HIV infection is possible. Pharmacists need to stay informed of these important breakthroughs in AIDS research in order to provide quality health information to patients in their community. This paper aims to evaluate the …

The Use Of Propranolol In The Treatment Of Posttraumatic Stress Disorder, Tana M. Peterman, Alison L. Huet, Sarah E. Drake, Jamie L. Drees, Robert D. Raiff, B. Shane Martin

Pharmacy and Wellness Review

This article examines the rising issue of post-traumatic stress disorder (PTSD) and possible treatment options. PTSD is a behavioral disorder resulting from memory formation and association with a traumatic event. A search of the published literature reveals several positive studies and case reports suggesting that propranolol, a beta adrenergic receptor antagonist, may be useful for both treatment and prevention of PTSD. Additionally, current studies are being completed in different population groups to determine the overall effectiveness and mechanism by which propranolol is able to provide relief from certain symptoms common to the disorder. This article discusses the medical evidence and …

Implications And Concerns Regarding The Mammogram Debate, Kristen Quertinmont, Breanne Rizzo, Caitlin Swan, Mary E. Klein, Lindsay Coram, Whitney N. Detillion, Anne F. Gentry, Natalie Dipietro, Brenda Rizzo

Pharmacy and Wellness Review

Screening procedures that detect breast cancer in its early stages are an important element of preventative health care for all women. When official guidelines and recommendations for screening are modified, their changes impact health care at both the population and individual patient levels. Recently, the United States Preventive Service Task Force (USPSTF) has developed new recommendations regarding when to start mammogram screening for breast cancer in women of average risk for the development of breast cancer. This article discusses the rationale behind the updated USPSTF recommendations and also presents the current American Cancer Society (ACS) guidelines.

Prescription Drug Abuse: A Guide For Pharmacists, Brieann J. Miller, Amanda C. Mcdavid, Nicholas J. Edmonds, Joshua P. Stevens, Cynthia C. Nguyen, Ryan W. Naseman, Michael M. Milks

Pharmacy and Wellness Review

Millions of Americans use prescription psychotherapeutc drugs for nonmedical purposes. The most commonly abused prescription drugs are painkillers, followed by sedatives and stimulants. The first step towards ending prescription drug abuse must be taken by the pharmacist. Professional and student organizations, as well the as the newly founded Ohio Rx Abuse Prevention (OhioRAP) Coalition, provide resources to pharmacists and pharmacy students who want to reduce prescription drug abuse. This article discusses these various resources and provides a guide for pharmacists to take an active role in reducing prescription drug abuse and positively impact patient outcomes and their communities.

Pharmacogenomics: Your Medical Identity, Hilary Stewart, Lisa Berni, Tyler Bulcher, Joel Rittenhouse, Ryan W. Naseman, Jon E. Sprague

Pharmacy and Wellness Review

Pharmacogenomics, the fusion of pharmacology and genomics, shows strong potential to solve many of today's dosing problems. lnter-patient dosing requirements, mainly due to genetic variability between patients, represent significant challenges for prescribers. Certain receptors, drug-targeted proteins, drug-transport mechanisms and drug-metabolizing enzymes are genetically established. Hence, any defect, absence or abnormality in the gene could alter how an affected individual will respond to a given drug. Due to advancements in technology, health care professionals who utilize pharmacogenomics may assess a patient's genetic profile and determine a predicted response to specific medications. This may result in potentially optimal dosing at the onset …

Role Of The Pharmacist In Improving Treatment For Children With Concurrent Gastrointestinal And Autism Spectrum Disorders, Whitney R. Henry, Kaitlin A. Sanders, Jenna L. Schaffner, Leslie M. Hart, Whitney N. Detillion, Anne F. Gentry

Pharmacy and Wellness Review

Over the last several years, a noteworthy association between gastrointestinal (GI) disorders and autism spectrum disorders (ASD) has been documented, although no large population-based studies exist. GI disorders in ASD children may stem from the underlying behavioral, communication, sensory or neurological issues intrinsic to the autistic disorder itself; therefore, the incorporation of alternative therapies, including behavioral modification, may be compelling treatment additions to the GI care traditionally recommended in children. To improve GI symptoms and quality of life in ASD children, a multidisciplinary approach is optimal, with pharmacists playing an active role in determining appropriate pharmacotherapy. Although there is a …

Options For Breast Cancer Prevention In High-Risk Patients, Ashley M. Overy, Lacey A. Shumate, Sarah M. Webb, Ashley E. Lehnert, Monica A. Weisenberger, Whitney N. Detillion, Andrew M. Roecker

Pharmacy and Wellness Review

Breast cancer is the most frequently diagnosed non-skin cancer in women, and one in eight women will develop breast cancer within their Iifetimes. Unfortunately, the strongest risk factors for breast cancer (i.e. age, family history, hormonal factors) are not easily modified. There is some evidence that chemopreventative drugs may be able to prevent breast cancer in high-risk patients. Tamoxifen and raloxifene have been shown to reduce the risk of breast cancer in high-risk women but may be associated with several serious adverse events. Clinical trials are currently in progress to determine if aromatase inhibitors are a viable alternative for breast …

A Review Of Dabigatran, An Oral Anticoagulant, Lindsey A. Hallman, Chad A. Rounds, Rebecca A. Carey, Nicole R. Hume, Karen L. Kier, James Spicer

Pharmacy and Wellness Review

Serious clinical complications associated with venous thrombotic embolism (VTE) necessitate prophylaxis in patient groups who are at high risk of VTE, specifically those recovering from orthopedic surgery with atrial fibrillation, with mechanical heart valves, at increased risk for stroke, or recovering post-MI. Currently, prophylaxis with warfarin, enoxaparin, or fondaparinux has been the standard of therapy, but these therapies each have their limitations. Dabigatran etexilate is an orally available pro-drug of dabigatran, a competitive, reversible, direct inhibitor thrombin (Factor lla). The agent is converted by esterases, and, thus, not associated with the complications of the CYP enzyme system. Dabigatran follows a …

Introduction & Medical Communications And Writing, Maggie Allen, Kate Klyczek, Anne F. Gentry

Pharmacy and Wellness Review

No abstract provided.

Reduce Patient Falls At Skilled Nursing Facility, Jalpa Patel

DNP Qualifying Manuscripts

Falls and related injuries are becoming a massive concern for healthcare systems. Preventing falls should be the top priority for healthcare organizations. Since the risk of falling cannot be eliminated, implementing a plan that addresses fall prevention strategies can significantly reduce the number of falls. This article explores evidence-based practice (EBP) interventions in order to prevent elderly patient falls in a skilled nursing facility (SNF). The EBP research interventions, such as fall screening tools used for patient assessment, safety education classes for staff, bedside nursing communication exchange, and daily nursing leadership rounds, can have a vital effect on patient and …