Medicine and Health Sciences Commons^™

Investigating The Influence That Service In A Pro Bono Clinic Has On A First Full-Time Clinical Education Experience From The Perspective Of Students And Their Clinical Instructors, Ellen Erdman, Jill D. Black, Sandra Campbell, Tim Golder, Stephen Grazioli, Kerstin M. Palombaro

Internet Journal of Allied Health Sciences and Practice

Purpose: Academic physical therapy programs strive to foster student readiness for full-time clinical education experiences in a variety of ways. This research looks at one program who has students participate in a student-run pro bono clinic for at least 60 hours prior to the first full-time clinic experience. The purpose of the study is to explore the influence that participation in this pro bono clinic has on a first full-time clinical education experience from the perspective of both the student and the clinical instructor (CI). Methods: Qualitative methodology was employed to gain the perspectives of 29 students and their respective …

Cervical Spine Thrust Joint Manipulation, Education, And A Home Exercise Program For The Management Of Individuals With Temporomandibular Disorder: A Prospective Case Series, Breanna Reynolds, Jamie L. Brown

Internet Journal of Allied Health Sciences and Practice

Background and Purpose: Temporomandibular disorder (TMD) often leads to chronic pain and disability. Current evidence supporting potentially effective physical therapy (PT) intervention in TMD is limited, however, some support exists for manual therapy, education, and exercise. The purpose of this case series was to describe outcomes in participants with TMD treated with cervical spine manual therapy, education, and exercise. Methods: Five participants (mean symptom duration 2.2 years) with TMD were treated with atlanto-occipital and C2-3 cervical spine thrust joint manipulation (TJM), behavioral education, and a home exercise program for 3 visits over 4 weeks. Primary outcomes included jaw range …

Grit And Academic Performance In Doctor Of Physical Therapy Students, Scott Richardson, Michael Scotto, Mayanne Belcina, Richa Patel, Kevin Wiener

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this study was to determine whether a physical therapy student’s level of grit positively correlates to graduate school grade point average. Methods: Participants were a convenience sample recruited from the class of 2021 in the Doctor of Physical Therapy program at Franklin Pierce University in Goodyear, Arizona. Subjects completed the Short Grit Scale (Grit-S) as a measure of grit. These scores were compared with participants’ graduate school grade point average using a Spearman Rho statistical test with data analysis completed using SPSS software. Results: 27 participants (15 males, 12 females) with mean grit score of 3.76 …

An Exploratory Study Of The Perceptions Of Footwear For Individuals Who Use Lower Limb Orthotics, Margaret E. Gegen, Teresa Plummer, Nancy Darr

Internet Journal of Allied Health Sciences and Practice

The purpose of this study was to explore individual’s perceptions of orthotics and footwear. A survey was created by the authors with the expert opinions of physical and occupational therapists and was distributed to two therapy clinics in Tennessee that provide both occupational therapy and physical therapy as well as on several online support groups. Seventy-nine (79) caregivers completed surveys. Thematic analysis was performed using Nvivo 10 (QSR International) and descriptive statistics were generated using the Statistical Package for the Social Sciences (SPSS) IBM International). Ninety percent (90%) of participants report that orthotics affect what type of shoes the user …

Characterization Of Bone Pathology In Sickle Cell Disease And Therapeutic Strategies, Mykel D. Green

Dissertations and Theses

Sickle cell disease (SCD) is a genetic hemoglobinopathy that has grown into a global health concern. While the advances in medical treatment and management of SCD during childhood have drastically improved the overall survival of children, the transition from pediatric to adult services is significantly inadequate in comparison. Life expectancies of patients with SCD in first world countries such as the United States are shortened to averages of 42 and 48 years for men and women, respectively. Despite the increasing number of people living with SCD, remarkably, few detailed studies have described the clinical course and complications of the disease …

Rural Malawian Women’S Resistance To Systematic Oppression, Violence, And Abuse By Their Husbands, Lucy Mkandawire-Valhmu, Wendy S. Bauer, Patricia E. Stevens, Loren W. Galvao, Katarina M. Grande, April Yerges, Lindsay Emer, Thokozani Mwenyekonde, Lance Weinhardt

College of Nursing Faculty Research and Publications

In Malawi, 41% of women aged 15 to 49 report ever experiencing intimate partner violence (IPV). Although there is evidence of the pervasiveness of IPV in Malawian society, the context in which it occurs and how women respond is not well described. The purpose of this study was to describe experiences of IPV of rural Malawian women. In-depth interviews were conducted with 55 rural Malawian women aged 21 to 75 years (M = 39) as part of a larger, mixed-methods study. This qualitative thematic analysis highlights husbands’ IPV against wives and women’s actions to protect themselves and their children, …

Nursing Research Priorities In Critical Care, Pulmonary, And Sleep: International Delphi Survey Of Nurses, Patients, And Caregivers: An Official American Thoracic Society Workshop Report, Maureen George, Carme Hernandez, Sheree Smith, Georgia Narsavage, Mary C. Kapella, Margaretann Carno, Jill L. Guttormson, Rebecca T. Disler, Diana E. Hart, Mary Beth Happ, Zijing Chen, Breanna Hetland, Ana F. Hutchinson, Helga Jonsdottir, Nancy S. Redeker, Hildy Schell-Chaple, Monica Fletcher, Janelle Yorke

College of Nursing Faculty Research and Publications

The objective of this workshop was to determine current nursing research priorities in critical care, adult pulmonary, and sleep conditions through input from consumer (patient, family, and formal and informal caregivers) and nursing experts around the world. Working groups composed of nurses and patients selected potential research priorities based on patient insight and a literature review of patient-reported outcomes, patient-reported experiences, and processes and clinical outcomes in the focal areas. A Delphi consensus approach, using a qualitative survey method to elicit expert opinion from nurses and consumers was conducted. Two rounds of online surveys available in English, Spanish, and Chinese …

Budget Impact Analysis Of Robotic Exoskeleton Use For Locomotor Training Following Spinal Cord Injury In Four Sci Model Systems, Daniel Pinto, Mauricio Garnier-Villarreal, Jason Barbas, Shuo-Hsiu Chang, Susan Charlifue, Edelle C. Field-Fote, Catherine L. Furbish, Candy Tefertiller, Chaithanya K. Mummidisetty, Heather Taylor, Arun Jayaraman, Allen W. Heinemann

College of Nursing Faculty Research and Publications

Background

We know little about the budget impact of integrating robotic exoskeleton over-ground training into therapy services for locomotor training. The purpose of this study was to estimate the budget impact of adding robotic exoskeleton over-ground training to existing locomotor training strategies in the rehabilitation of people with spinal cord injury.

Methods

A Budget Impact Analysis (BIA) was conducted using data provided by four Spinal Cord Injury (SCI) Model Systems rehabilitation hospitals. Hospitals provided estimates of therapy utilization and costs about people with spinal cord injury who participated in locomotor training in the calendar year 2017. Interventions were standard of …

Parent Readiness For Hospital Discharge Scale: Psychometrics And Association With Postdischarge Outcomes, Marianne E. Weiss, Stacee M. Lerret, Rachel Schiffman

College of Nursing Faculty Research and Publications

Introduction The purpose of this study is to validate the Readiness for Hospital Discharge Scale (RHDS) for use with parents of hospitalized children. PedRHDS is a structured tool for a discharge readiness assessment before pediatric discharge. Methods Using combined data from four studies with 417 parents, psychometric testing and item reduction proceeded with principal component analysis for factor structure delineation, Cronbach's alpha for reliability estimation, and regression analysis for predictive validity. Results A 23-item PedRHDS retained the a priori factor structure. Reliability ranged from 0.73 to 0.85 for the 23-item and 10- and 8-item short scales. PedRHDS (all forms) was …

Infant Illness Severity And Perinatal Post-Traumatic Stress Disorder After Discharge From The Neonatal Intensive Care Unit, Kathryn J. Malin, Teresa S. Johnson, Sarah Mcandrew, Jacqueline Westerdahl, Jonathan Leuthner, Joanne Lagatta

College of Nursing Faculty Research and Publications

Background

Risk factors for perinatal posttraumatic stress disorder (PTSD) among parents of an infant in the NICU have varied in previous literature. The relationships between perception of illness severity and objective measures of illness severity with PTSD are not well understood.

Aims

To determine if PTSD among parents after an infant NICU discharge can be predicted by 1) objective measures of infant illness severity or 2) perceptions of infant illness severity.

Study design

A prospective, observational study.

Subjects

Parent/infant dyads who were in the NICU for ≥14 days.

Outcome measures

Objective measures of illness severity were obtained from the electronic …

Mechanisms Of Value-Biased Prioritization In Fast Sensorimotor Decision Making, Kivilcim Afacan-Seref

Dissertations and Theses

In dynamic environments, split-second sensorimotor decisions must be prioritized according to potential payoffs to maximize overall rewards. The impact of relative value on deliberative perceptual judgments has been examined extensively, but relatively little is known about value-biasing mechanisms in the common situation where physical evidence is strong but the time to act is severely limited. This research examines the behavioral and electrophysiological indices of how value biases split-second perceptual decisions and the possible mechanisms underlying the process. In prominent decision models, a noisy but statistically stationary representation of sensory evidence is integrated over time to an action-triggering bound, and value-biases …

Clinical Nurses' Perspectives On Discharge Practice Changes From Participating In A Translational Research Study, Kathleen L. Bobay, Regina Conway-Philips, Ronda G. Hughes, Linda L. Costa, Sarah J. Bahr, Danielle M. Siclovan, Susan A. Nuccio, Marianne E. Weiss

College of Nursing Faculty Research and Publications

Aim

To describe clinical nurses' experiences with practice change associated with participation in a multi‐site nursing translational research study implementing new protocols for hospital discharge readiness assessment.

Background

Nurses' participation in translational research studies provides an opportunity to evaluate how implementation of new nursing interventions affects care processes within a local context. These insights can provide information that leads to successful adoption and sustainability of the intervention.

Methods

Semi‐structured focus groups from 30 of 33 participating study hospitals lead by team nurse researchers.

Results

Nurses reported improved and earlier awareness of patients' discharge needs, changes in discharge practices, greater patient/family …

Feasibility And Acceptability Of A Game-Based Symptom-Reporting App For Children With Cancer: Perspectives Of Children And Parents, Lauri Linder, Amy Rose Newman, Kristin Stegenga, Yin-Shun Chiu, Sarah E. Wawrzynski, Heidi Kramer, Charlene Weir, Scott Narus, Roger Altizer

College of Nursing Faculty Research and Publications

Background

Children with cancer have difficulty identifying and describing the multiple symptoms they experience during hospitalization and between clinical encounters. Mobile health resources, including apps, are potential solutions to support child-centric symptom reporting. This study evaluated the feasibility and acceptability of a newly developed game-based symptom-reporting app for school-age children with cancer.

Procedure

Nineteen school-age children (6–12 years of age) receiving treatment for cancer at a COG institution in the Intermountain West of the United States used a game-based symptom-reporting app between clinical visits. Feasibility was evaluated through a summary of actual days of app use and interaction with each …

Living The Manatt Report: Advancing The Future Of Nursing Through Joint Academic Appointments, Jennifer K. Pfister, Jill C. Kuester, Katie Mcdermott, Leslie Talbert, Christine A. Schindler

College of Nursing Faculty Research and Publications

In 2016, the American Association of Colleges of Nursing published the Manatt Report which outlines recommendations to address the future of academic nursing. This report asserts that in order to influence the direction of healthcare, academic nursing needs to partner with academic health centers in leadership positions, embrace current clinical practice, and prioritize research. The following paper details the successful implementation of joint academic appointments between a college of nursing and a medical college. Joint appointments have formalized the role of clinician-educator, brought current clinical knowledge to academia, and allowed for protected academic time that is focused on enhancing the …

Blood Flow Improvement Trial: Design And Enrollment Developing Topics, Maiya F. Macalpine, Margo B. Heston, Julian M. Gaitán, Ozioma C. Okonkwo, Barbara B. Bendlin, Kimberlee A. Gretebeck, Randall J. Gretebeck

College of Nursing Faculty Research and Publications

Background

Midlife insulin resistance (IR) has previously been shown to be associated with lower cerebral blood flow (CBF), and is a potentially modifiable risk factor for dementia. The Blood Flow Improvement Trial (BFiT), NCT03117829 , tested a 12 week carbohydrate restricted diet (CRD) and exercise behavioral intervention to reverse IR, and aimed to 1) determine the extent to which improving or normalizing glucose homeostasis improves CBF and cognitive function in individuals with IR, 2) determine whether participants continue to maintain improved or normalized glycemic control for 6 months, and 3) determine changes in the human metabolome as individuals improve or …

Antifungal Defense Molecules From Bacterial Symbionts Of North American Trachymyrmex Ants, Georgia Scherer

CMC Senior Theses

Defensive symbioses, in which microbes provide molecular defenses for an animal host, hold great potential as untapped sources of therapeutically useful antibiotics. Fungus-growing ants use antifungal defenses from bacterial symbionts to suppress pathogenic fungi in their nests. Preliminary chemical investigations of symbiotic bacteria from this large family of ants have uncovered novel antifungal molecules with therapeutic potential, such as dentigerumycin and selvamicin.

In this study, the bacterial symbionts of North American Trachymyrmex fungus-growing ants are investigated for antifungal molecules. Plate-based bioassays using ecologically-relevant fungal pathogens confirmed that these bacteria have antifungal activity. In order to purify and identify the antifungal …

Observing The Effects Of Antimalarial Drug Availability On Women’S Work Absenteeism, Rei Imada

CMC Senior Theses

This study aims to provide insight on how availability of antimalarial drugs can help alleviate the economic burden of malaria. Much of the existing literature that looks into the effects of antimalarial drug availability focuses on the associated health benefits, but fails to draw a link to the economic benefits that may also be incurred. Using data from the 2015-2016 Tanzania Demographic and Health Survey and Malaria Indicator Survey, this study performs a series of multiple regressions to observe how increased availability of artemisinin-based combination therapies (ACTs), a front-line antimalarial drug in most African countries, affects likelihood of work absenteeism …

Surfacing Contexts Of Violence In Novel Forms Of The Reproductive Justice Framework Through Lessons From Latin America: A Study Of Brutality, Migration And Bodily Autonomy And Progressive Solutions For Use In Public Health, Angelica M. Campos

CMC Senior Theses

In the last 5 years, Latin America has witnessed a tenacious wave of pañuelo verde and #NiUnaMenos activism. Sparked by increasing mortality rates associated with unsafe, clandestine abortions and femicide, the praxes and fundamental elements of these social movements have proven themselves useful not only in garnering international attention on issues relating to bodily autonomy, but in the synthesis of their respective sociopolitical solutions as well. In the United States, similar efforts have been spearheaded by the lauded reproductive justice framework, which has often been credited for centering the plight of women of color in both reproduction and social justice. …

Evaluating Interpersonal Problems In Anorexia Nervosa Through The Lens Of Polyvagal Theory, Marika Morelan

CMC Senior Theses

Eating disorders are an increasingly prevalent issue, especially among young women. While they aren’t a new phenomenon, they are historically under-researched, and remain widely misunderstood. Without understanding the causes underlying these disorders or the mechanisms working to maintain them, treating them successfully has proved to be incredibly difficult. This is especially the case with Anorexia Nervosa. Out of the six eating disorders in the DSM-5, it has the lowest treatment success rate and an alarmingly high relapse rate. Treating the disorder through weight restoration and the extinction of compensatory behaviors alone does not fully resolve the disordered pathology; interpersonal problems …

Determining The Antibacterial Activity And Mode Of Action Of Tirandamycin, Hailey Bouchard

CMC Senior Theses

Tirandamycin is a small molecule natural product that has been isolated from various species of marine and terrestrial Streptomyces. The natural product has shown antibacterial activity against an array of Gram-positive and Gram-negative bacteria, showing promise as a pharmaceutical drug. Tirandamycin has 14 known derivatives, many of which have been created synthetically. Some of its derivatives are particularly potent against the high-risk bacteria vancomycin-resistant Enterococcus faecium, Staphylococcus aureus, Streptococcus agalactiae, Streptococcus pneumoniae and Escherichia coli. However, the antibacterial potency of these derivatives has not been tested systematically leading to the possibility of discovering more potent …

Momentum 2020, Stephanie Clarke

Momentum

A journal of undergraduate research

Disparities In The Prevalence And Risk Factors Of Anaemia Among Children Aged 6–24 Months And 25–59 Months In Ethiopia, Tafere Gebreegziabher Belay, Nigatu Regassa, Micaela Wakefield, Kelly Pritchett, Susan Hawk

All Faculty Scholarship for the College of Education and Professional Studies

Despite global efforts made to address anaemia, the prevalence remains high in most Sub-Saharan African countries. In Ethiopia, anaemia poses a very strong public health concern. The purpose of the present study was to examine the key risk factors related to anaemia among children aged 6–24 months (younger age group) and 25–59 months (older age group). We used the 2016 Ethiopian Demographic and Health Survey data, collected from 11 023 mothers with under five children. Ordered logistic regression modelling was used for assessing risk factors of childhood anaemia. The results suggest that the prevalence of anaemia was 72 % in …

Ampk In The Ventromedial Nucleus Of The Hypothalamus: A Key Regulator For Thermogenesis, Hailan Liu, Yong Xu, Fang Hu

Children’s Nutrition Research Center Staff Publications

Obesity has become a global health issue, but effective therapies remain very limited. Adaptive thermogenesis promotes weight loss by dissipating energy in the form of heat, thereby representing a promising target to counteract obesity. Notably, the regulation of thermogenesis is tightly orchestrated by complex neuronal networks, especially those in the hypothalamus. Recent evidence highlights the importance of adenosine monophosphate-activated protein kinase (AMPK) within the ventromedial nucleus of the hypothalamus (VMH) in modulating thermogenesis. Various molecules, such as GLP-1, leptin, estradiol, and thyroid hormones, have been reported to act on the VMH to inhibit AMPK, which subsequently increases thermogenesis through the …

Development Of A Rapid And Efficient Protoplast Isolation And Transfection Method For Chickpea (Cicer Arietinum), Ninghui Cheng, Paul A Nakata

Children’s Nutrition Research Center Staff Publications

Chickpea (Cicer arietinum L.) is the second most important grain legume worldwide. Recent advances in the sequencing of the chickpea genome has provided a new and valuable resource to aid efforts in gene discovery and crop trait improvement. Technical difficulties in stable chickpea transgenics and the lack of a transient expression system for rapid analysis of gene expression and function; however, has limited the usefulness of this genomic resource. As a step toward alleviating this limitation, we report here the development of a simple and efficient transient gene expression protocol. Using leaves from chickpea seedlings, we have established a …

Classify Multicategory Outcome In Patients With Lung Adenocarcinoma Using Clinical, Transcriptomic And Clinico-Transcriptomic Data: Machine Learning Versus Multinomial Models, Fei Deng, Lanlan Shen, He Wang, Lanjing Zhang

Children’s Nutrition Research Center Staff Publications

Classification of multicategory survival-outcome is important for precision oncology. Machine learning (ML) algorithms have been used to accurately classify multi-category survival-outcome of some cancer-types, but not yet that of lung adenocarcinoma. Therefore, we compared the performances of 3 ML models (random forests, support vector machine [SVM], multilayer perceptron) and multinomial logistic regression (Mlogit) models for classifying 4-category survival-outcome of lung adenocarcinoma using the TCGA. Mlogit model overall performed similar to SVM and multilayer perceptron models (micro-average area under curve=0.82), while random forests model was inferior. Surprisingly, transcriptomic data alone and clinico-transcriptomic data appeared sufficient to accurately classify the 4-category survival-outcome …

Automated Phonetic Transcription Grading Tool (Aptgt), Marisha Speights Atkins, Dallin J. Bailey, Cheryl D. Seals, Guorui Li, Robertson Bassy, Yang Cao, Sicheng Li, Bennett Abigail

Faculty Publications

The Automated Phonetic Transcription Grading Tool (APTgt) is an online Learning Management System (LMS) that facilitates the comparison of phonetic transcriptions for instruction and clinical training purposes. It uses an embedded IPA graphical keyboard for transcription input. A custom edit distance algorithm aligns transcriptions in an intuitive way and then calculates differences quantitatively. This allows for objective scoring of transcriptions of even severely impaired productions, which may be difficult to score via traditional comparison methods. APTgt also includes support for comparing narrow phonetic transcriptions with diacritics. Contact the Technologies for Speech Language Pathology Research Lab at [email protected] for registration information.

Telehealth Efforts To Reduce Hospital Readmissions Of Congestive Heart Failure Patients, Sirfornia L. Deasfernandes

Walden Dissertations and Doctoral Studies

Congestive heart failure (CHF) is a chronic condition that affects millions of individuals in the United States. There is no cure for CHF, but medical interventions can help treat the symptoms and improve health outcomes. The purpose of this quantitative study was to determine if telehealth services help to reduce the readmission status of patients diagnosed with CHF. The theoretical framework used in this study was the individual and family self-management theory to help focus on self-management behaviors that contribute to improving the patients' health outcomes. The research questions were focused on addressing CHF patients receiving telehealth services and whether …

The Effects Of A Plant-Based Diet On Inflammation Of Patients With Cardiac Disease, Rachel L. Butcher

Honors Undergraduate Theses

Cardiac disease is the primary cause of death in the United States of America (CDC, 2017). Despite ongoing efforts and investments to improve cardiac health in the United States, most of the population will suffer from cardiovascular diseases. There is a multitude of research supporting that diet can contribute to cardiac disease, but it is less known that diet can greatly contribute to regulation and reversal of cardiovascular disease processes (Huang et al., 2012; Satija et al., 2017; Kim et al., 2019). Existing research supports the efficacy of plant-based diets to manage and reverse certain cardiac diseases (Tuso et al., …

Hospital Footwear As A Vector For Organism Transmission, David J. Frederick

Honors Undergraduate Theses

In the United States healthcare system, nearly one in 31 patients contract a nosocomial infection. Footwear worn in these hospital settings are a factor that should be considered when determining contributing agents and methods for organism transmission. The purpose of this review is to synthesize the current research on hospital footwear as a vector for organism transmission. Eight studies were included in this review to examine the impact of wearable interventions on footwear-related contamination in the hospital setting and organism transfer as it relates to footwear and hospital environments. The link between the organism load and diversity on hospital worn …

Millennial Attitudes Toward Telehealth: An Integrative Literature Review, Hannah Gwyneth Y. Tabora

Honors Undergraduate Theses

Purpose: The primary purpose of this research was to explore individuals born in the millennial generation’s likelihood of using telehealth and virtual office visits as a replacement for face to face provider interactions. The secondary purpose was to examine the feasibility and access of treatable conditions and ailments in a virtual environment.

Methods: A literature review exploring millennials and telehealth was performed using various databases with search terms combined to include: ‘millennials*’, ‘telehealth*’, ‘telemed*’, ‘finance*’, ‘primary care*’, ‘healthcare*’, ‘health knowledge*’, ‘literacy*’, ‘education*’, ‘misinformation*’. The data was conformed into tables that synthesized the relationship between the millennial generation and their access …