Medicine and Health Sciences Commons^™

The Impact Of Nurse Stress, Job Distress, Job Satisfaction And Mood On Patient Outcomes, Madelynne Wright

Undergraduate Honors Thesis Collection

This study examined the intercorrelations among nursing home healthcare providers’ stress, job distress, job satisfaction, and mood, as well as the relationships between these factors and patient outcomes. Additionally, this study investigated the impact Butler University’s Music First! program had on nurse job perceptions. A total of 63 nurses from 9 long-term care facilities completed questionnaires asking about stress, job distress, and global job satisfaction. Nurses’ depression, anxiety and hostility were also assessed with a 15-item Profile of Mood States questionnaire. Of these 63 nurses, 20 completed the questionnaires at three different time points during the implementation of the Music …

Language-Deprived Environments: Neonatal Intensive Care Units And Hearing Loss, Margaret Caesar

Undergraduate Honors Thesis Collection

Adequate language exposure is crucial for speech-language development in children. Previous research suggests that decreased language exposure leads to an increased risk for speech-language developmental delays. This study aims to explore the language exposure of two arguably language-deprived environments: Neonatal Intensive Care Units (NICU) and severe-to-profound hearing loss. This is a two-part study that examines caregiver-infant interactions through the analysis of infant-directed speech (IDS). In the first part of the study, researchers transcribed and analyzed pre-recorded Language Environment Analysis (LENA) audio recordings of five (5) infants with severe-to-profound hearing loss (6-months post cochlear implantation). These LENA recordings collected speech, language, …

Emergent Shift To Telepractice During The Covid-19 Pandemic By School-Based Speech-Language Pathologists, Charlotte May Hilker

Undergraduate Honors Thesis Collection

Purpose: Schools across America closed abruptly and indefinitely starting March 2020 due to the COVID-19 pandemic. As a result, speech-language pathologists (SLPs) working in these schools turned to telepractice to meet the needs of their clients. Telepractice is a relatively new service delivery model in the field of speech-language pathology. Challenges related to telepractice include clinicians’ limited hours of training for telepractice, clients’ lack of access to telehelpers during therapy, and both clinician and client beginning to work from home, and issues with working from home. The aim of the current study was to assess how these issues affect telepractice …

The Influence Of Music Training And Bilingualism On Speech And Music Perception, Allison Marie Smith

Undergraduate Honors Thesis Collection

This case study investigates the role that bilingualism and/or music training plays on the pitch perception of non-native speech and musical pitch contrasts in 6- to 7-year-old children. This study aimed to investigate two research questions. First, does the infant bilingual advantage in pitch perception persist through childhood? Second, does music training lead to an advantage in pitch perception? There were 4 participants with the following criteria: a monolingual non-musician, monolingual musician, bilingual non-musician, and a bilingual musician. The participants performed a series of perception tasks, including English minimal pairs, Mandarin pitch contrasts, and violin pitch contrasts. It was found …

On The Proposed Legalization Of Commercial Surrogacy: I Thought We Had Abolished The Sale Of Human Beings, Phyllis Chesler

Dignity: A Journal of Analysis of Exploitation and Violence

No abstract provided.

Where Do We Go From Here? A Forward-Thinking Vision For Physiology Undergraduate Education, Nancy M. Aguilar-Roca, Lisa C. Anderson, Anne R. Crecelius, Michelle B. French, Katie Johnson, Jenny L. Mcfarland, Jennifer Rogers, Claudia I. Stanescu, Erica A. Wehrwein

Health and Sport Science Faculty Publications

This paper is a summary of the special collection of papers in Advances in Physiology Education dedicated to the Physiology Majors Interest Group (P-MIG). P-MIG is a new and vibrant community (1, 2) of educators and administrators who are united by the common goal of creating physiology courses, curricula and programs that will prepare our students for the future. It is an independent consortium that welcomes anyone interested in physiology education at the level of the undergraduate degree in physiology and physiology-related fields. As demonstrated by this special collection of papers of Advances in Physiology Education, P-MIG has already made …

Neonatal Jaundice And Developmental Impairment Among Infants In Kilifi, Kenya, Dorcas N. Magai, Michael Mwaniki, Amina Abubakar, Shebe Mohammed, Anne L. Gordon, Raphael Kalu, Paul Mwangi, Hans M. Koot, Charles R. Newton

Institute for Human Development, East Africa

Background: Neonatal jaundice (NNJ) is common in sub‐Saharan Africa (SSA), and it is associated with sepsis. Despite the high incidence, little has been documented about developmental impairments associated with NNJ in SSA. In particular, it is not clear if sepsis is associated with greater impairment following NNJ.

Methods: We followed up 169 participants aged 12 months (57 cases and 112 controls) within the Kilifi Health Demographic Surveillance System. The diagnosis of NNJ was based on clinical laboratory measurement of total serum bilirubin on admission, whereas the developmental outcomes were assessed using the Developmental Milestones Checklist and Kilifi Development …

Post Chemotherapeutic Treatment Impact On Pediatric Patients With Acute Lymphoblastic Leukemia, Roaa Alfarshooti

Wayne State University Theses

Acute lymphoblastic leukemia (ALL) is the most prevalent type of leukemia among children. It is characterized by chromosomal and genetic variations and abnormalities occurring in the leukemic cells. Prognosis predictors of ALL depend on risk-based stratification and the reaction to the initial therapy. Current treatment regimens of ALL contribute to the survival of approximately 80% of pediatric ALL patients with 90% 5-year event-free survival. Based on the patient’s features impacting prognosis and risk of therapy failure, cases can be designated to receive the adequate type of treatment regimens. The higher the risk, the more aggressive, intensive, and toxic is the …

A Patient-Centered Ethnographic Interview And Measurement Of Intelligibility In Spastic-Ataxic Dysarthria For People With Multiple Sclerosis, Courtney Marie Leppek

Wayne State University Theses

Multiple sclerosis (MS) produces neurological impairments that are variable in duration and severity, and that are unique to each case of MS. In addition to variability of symptoms, the length of the MS diagnostic process often affects quality of life. In this mixed qualitative and quantitative study, we used ethnographic interviews to investigate the underlying thoughts and feelings of two very different individuals with MS and Spastic-Ataxic Dysarthria. The results contribute to the understanding of MS as a multi-faceted condition that has implications that are both internal and external to the person with MS. Further, the results reflect the clinical …

Pilot Evaluation Of The Computer-Based Assessment Of Non-Cognitive Attributes Of Health Professionals (Cana-Hp), Sara Faye Maher

Wayne State University Dissertations

To meet the needs of complex and/or underserved patient populations, health care professionals must possess diverse backgrounds, qualities, and skill sets. Holistic review has been used to diversify student admissions through examination of non-cognitive attributes of health care applicants. The objective of this study was to develop a novel methodology, the computer-based assessment of non-cognitive attributes of health professionals (CANA­ HP), to effectively screen non-cognitive attributes of applicants. Three research questions were delineated; 1.) To determine the CANA-HP instrument reliability (internal consistency & interrater), 2.) To determine if the CANA-HP measured attributes of non­cognitive variables, as demonstrated by low construct …

Effects Of Remote Limb Ischemic Conditioning On Muscle Strength In Healthy Young Adults: A Randomized Controlled Trial, Swati M. Surkar, Marghuretta D. Bland, Anna E. Mattlage, Ling Chen, Jeffrey M. Gidday, Jin-Moo Lee, Tamara Hershey, Catherine E. Lang

Open Access Publications

Remote limb ischemic conditioning (RLIC) is a clinically feasible method in which brief, sub-lethal bouts of ischemia protects remote organs or tissues from subsequent ischemic injury. A single session of RLIC can improve exercise performance and increase muscle activation. The purpose of this study, therefore, was to assess the effects of a brief, two-week protocol of repeated RLIC combined with strength training on strength gain and neural adaptation in healthy young adults. Participants age 18-40 years were randomized to receive either RLIC plus strength training (n = 15) or sham conditioning plus strength training (n = 15). Participants received RLIC …

Vibrational Spectroscopy For In Vitro Monitoring Stem Cell Differentiation, Francesca Ravera, Esen Efeoglu, Hugh Byrne

Other resources

Stem cell technology has attracted considerable attention over recent decades due to its enormous potential in regenerative medicine and disease therapeutics. Studying the underlying mechanisms of stem cell differentiation and tissue generation is critical, and robust methodologies and different technologies are required. Towards establishing improved understanding and optimised triggering and control of differentiation processes, analytical techniques such as flow cytometry, immunohistochemistry, reverse transcription polymerase chain reaction, RNA in situ hybridisation analysis, and fluorescence-activated cell sorting have contributed much. However, progress in the field remains limited because such techniques provide only limited information, as they are only able to address specific, …

Reflections In Systemic Family Psychotherapy And Adult Mental Health Services In The South East Of Ireland; And Beyond., Sean Edward Boland, Annette Byrne, Caroline Kavanagh, Sean O'Neill, Catherine Mahon, Kate Doran, Wille Hackett

Staff Articles and Research Papers

Systemic Family Psychotherapy (SFP) has been involved in the Carlow Kilkenny South Tipperary Adult Mental Services since 1994: in the main this involved meeting with service users, their families, couples and friends. However, from 2012 to 2019 five SFPs retired. This occurred when decisions were made by some Mental Health Management not to replace those SFPs that retired: thereby reducing the number of SFPs in the Southeast Adult Mental Health Services (AMHS); presumably due to funding difficulties at that time. However, as the months and years went by it became oblivious that two AMHSs were not going to employ SPTs. …

Singlet Oxygen Generation By Porphyrins And Metalloporphyrins Revisited: A Quantitative Structure-Property Relationship (Qspr) Study, Andrey A. Buglak, Mikhail Filatov, Althaf M. Hussain, Manabu Sugimoto

Books/Book chapters

state followed by formation of singlet oxygen (1O2), which is a highly reactive species and mediates various oxidative processes. The design of advanced sensitizers based on porphyrin compounds have attracted significant attention in recent years. However, it is still difficult to predict the efficiency of singlet oxygen generation for a given structure. Our goal was to develop a quantitative structure-property relationship (QSPR) model for the fast virtual screening and prediction of singlet oxygen quantum yields for pophyrins and metalloporphyrins. We performed QSPR analysis of a dataset containing 32 compounds, including various porphyrins and their analogues (chlorins and bacteriochlorins). Quantum-chemical descriptors …

A Four-Week Fundamental Motor Skill Intervention Improves Motor Skills In Eight To 10-Year-Old Irish Primary School Children, Keith Costello, Joe Warne

Articles

Aim: To determine if a four-week fundamental motor skills intervention improves fundamental motor skills in Irish school children. Methods: 100 Primary School boys (n = 58) and girls (n = 42) participated in this study (Age 9 ± 1 years, equally divided into a control and intervention group. Proficiency was assessed qualitatively using the Fundamental Motor Skills Quotient (FMSQ) pre and post intervention, and between gender. Results: There was no change in the control group over time (p = 0.54; Mean change = 0.06 [−0.14 to 0.26]; Cohen’s d = 0.01 [Trivial]). In the intervention group, both the male (p …

A Chronic Strain Of The Cystic Fibrosis Pathogen Pandoraeapulmonicola Expresses A Heterogenous Hypo-Acylated Lipid A, Molly D. Pither, Siobhan Mcclean, Alba Silipo, Antonio Molinaro, Flaviana Di Lorenzo

Articles

Pandoraeasp. is an emerging Gram-negative pathogen in cystic fibrosis causing severe and persistent inflammation and damageof the lungs. The molecular mechanisms underlying the high pathogenicity ofPandoraeaspecies are still largely unknown. AsGram-negatives,Pandoraeasp. express lipopolysaccharides (LPS) whose recognition by the host immune system triggers aninflammatory response aimed at the bacterial eradication from the infected tissues. The degree of the inflammatory responsestrongly relies on the fine structure of the LPS and, in particular, of its glycolipid moiety, i.e. the lipid A. Here we report thestructure of the lipid A isolated from the LPS of a chronic strain ofP. pulmonicola(RL 8228), one of the …

Monitoring Wellness, Training Load, And Running Performance During A Major International Female Field Hockey Tournament, Aideen Mcguinness, Gerard Mcmahon, Shane Malone, Darren Kenna, David Passmore, Kieran Collins

Articles

The current observational study quantified players' activity profiles during a major international female field hockey tournament and determined whether an association exists between well-being measures and running performance within elite female hockey players. Elite female field hockey players (23 6 3 years; 162.6 6 13 cm; and 66 6 6 kg) participated in the study. Participants running performance was monitored using global positioning system technology (S5; Catapult Innovations , Scoresby, Victoria, Australia), with daily well-being questionnaires used to quantify player responses during the tournament. Thresholds for the magnitude of the observed change for each variable were determined using the Hopkins …

Training And Technique Choices Predict Self-Reported Running Injuries: An International Study, Joe Warne, Allison H. Gruber, Roy Cheung, Jason Bonacci

Articles

The aim of this study was to describe the self-reported injury, training, and running technique choices of regular runners in four international regions. Design and Setting 756 participants began an expert derived self-report online survey in Ireland, USA, Hong Kong and Australia. Participants 325 participants completed the survey (age=38±10years; weight=68.0±13.1kg; height=1.70±0.10m). Main Outcome Measures Descriptive statistics are reported examining injury incidence and location; shoe and orthosis choices; and training and technique practices. A backwards logistic regression was implemented to examine associations between injury and training choices. Results 68.3% reported having an injury in the last year. 81.45% of these injuries …

Association Between Eccentric Knee Flexor Strength And Hamstring Injury Risk In 185 Elite Gaelic Football Players, Mark Roe, Eamonn Delahunt, Malachy Mchugh, Conor Gissane, Shane Malone, Kieran Collins, Catherine Blake

Articles

Hamstring strains are the most common time-loss injury in elite Gaelic football affecting over 20% of players per season. Thus, there is a need to identify factors contributing to the onset of hamstring injuries in order to inform injury risk management strategies. The current study investigated whether eccentric knee flexor strength and between-limb imbalances were associated with increased risk of sustaining a timeloss hamstring injury in elite Gaelic football players. A total of 185 elite male players (26.9 ± 2.7 years, 86.4 ± 6.2 kg, 183.4 ± 5.6) were prospectively followed for 12 weeks from the day of testing. Injury …

Identification Of Maximal Running Intensities During Elite Hurling Match-Play, Damien Young, Shane Malone, Marco Beato, Laurent Mourot, Giuseppe Coratella

Articles

The current study aimed to describe the duration-specific running intensities of elite hurling players during competition with respect to position using a rolling average method. Global positioning systems (10-Hz Viper; STATSport, Viper, Newry, Northern Ireland) were used to collect data from 36 elite hurling players across 2 seasons. Players were categorized according to playing positions (full-backs, half-backs, midfielders, half-forwards, and full-forwards). A total of 230 full match samples were obtained from 22 competitive games for analysis. The velocity-time curve was analyzed using a rolling average method, in which the maximum relative total distance (TD; m·min), high-speed running distance (HSR; m·min), …

Tick-Borne Infections In New Hampshire: An Evaluation Of The Diagnostic Process In A Local Patient Population, Katherine Anderson

Honors Theses and Capstones

Overall, approximately 95 percent of reported cases of vector-borne disease were associated with ticks, making these the most medically important group of arthropods in the United States.¹ Despite the prevalence of tick-borne infections, the process for the diagnosis of this condition is not well studied. This study aims to analyze data from a pool of 100 patients who underwent testing for tick-borne disease in the same institution in Dover, New Hampshire during the most recent peak tick season of 2019. Information utilized in this study included: patient age, sex, location of testing (inpatient versus outpatient), diagnostic testing methods used …

Changes In Bone Health Of Female College Students, Sarah E. Pogany, Jesse Morrell, Maggie Dylewski Begis, Gretchen Arnold

Honors Theses and Capstones

Objective: Identifying individuals with low bone ultrasound attenuation (BUA) z-scores under the age of 30 can allow for improvements of bone health through increased intake of calcium and vitamin D, physical activity, and avoidance of excessive alcohol or caffeine intake. The goal of this study was to assess changes in bone health and observe related risk factors among female college students.

Participants and Methods: Female students (n=38) enrolled in the Nutrition Program at the University of New Hampshire (UNH) who participated in the College Health and Nutrition Assessment Survey (CHANAS) were recruited to participate in a follow-up study …

The Relationship Between Social Media Engagement And Psychological Well-Being In College Students At The University Of New Hampshire, Emily G. D'Antonio

Honors Theses and Capstones

Social media use has increased substantially in recent years, and for the college-aged population, social media is often the leading method of communication. Research indicates this reliance on digital connection could have a negative impact on the health of young adults (Bagroy et al., 2017). The college years are a time of personal growth and defining actions, yet can also be burdened by mental health issues related to stress, anxiety, and depression (Hunt & Eisenberg, 2010). Acknowledging these trends, the current study explores how college students’ specific frequency and intentionality while interacting on social media relates to their psychological well-being. …

The Cholera Crisis In Yemen: Case Studies On Vulnerability And Resilience In Sana'a, Al Hudaydah, And Ma'areb, Noor Albannein A. Al-Saad

Honors Theses and Capstones

The largest recorded cholera epidemic in history is happening right now in Yemen, a country which has reported over 2 million cases of cholera as of 2020. Yemen has a history of endemic cholera, but prolonged conflict in the country has led to deteriorating conditions that have triggered massive outbreaks of the disease. The purpose of this study is to investigate the direct and indirect causes of the cholera epidemic in Yemen by proposing factors that may confer vulnerability and resilience in Yemeni governorates. Case studies were constructed for three governorates: Sana’a and the inner municipality of Amanat Al Asimah; …

The Efficacy Of The Healthy Families Flourish Program For Families Raising Children With Autism Spectrum Disorder, Carli Madalena Rita

Honors Theses and Capstones

The family unit is the driving force that creates a foundation for life satisfaction and wellbeing of a child that extends across the lifespan. Understanding family health and family participation in meaningful daily activities are critical components of family life lacking in current research, especially for families raising children with autism spectrum disorder (ASD). This study seeks to determine the effectiveness of an occupational therapy intervention program designed to support families raising children with ASD to identify and overcome barriers to everyday family activities. The Healthy Families Flourish Program is a 10-session occupational therapy intervention program developed for this study …

Untangling The Dorsal Diencephalic Conduction System: A Review Of Structure And Function Of The Stria Medullaris, Habenula And Fasciculus Retroflexus, Elena Roman, Joshua Weininger, Basil Lim, Marin Roman, Denis Barry, Paul Tierney, Erik O'Hanlon, Kirk Levins, Veronica O'Keane, Darren Roddy

Other

The often-overlooked dorsal diencephalic conduction system (DDCS) is a highly conserved pathway linking the basal forebrain and the monoaminergic brainstem. It consists of three key structures; the stria medullaris, the habenula and the fasciculus retrofexus. The frst component of the DDCS, the stria medullaris, is a discrete bilateral tract composed of fbers from the basal forebrain that terminate in the triangular eminence of the stalk of the pineal gland, known as the habenula. The habenula acts as a relay hub where incoming signals from the stria medullaris are processed and subsequently relayed to the midbrain and hindbrain monoaminergic nuclei through …

Let She Who Has The Womb Speak: Regulating The Use Of Human Oocyte Cryopreservation To The Detriment Of Older Women, Browne C. Lewis

Law Faculty Articles and Essays

This article is divided into three parts. Part I examines the arguments in favor of banning human oocyte cryopreservation. Part II explores the reasons some opponents of human oocyte cryopreservation might give to support restrictions on the use of frozen oocytes. Part III analyzes the possible ethical and legal challenges that may arise in the event that the government seeks to ban the use of frozen oocytes or restrict the use of frozen oocytes based solely on the age of the potential mother.

New Perspectives On Faculty Stress: Its Relationship With Work Engagement, Teaching Effectiveness, And Program Preferences To Manage Stress, Rocio Alvarenga

Open Access Theses & Dissertations

The purpose of the study was to analyze faculty stress with three interrelated parts. First, the study examined the relationship between work engagement, stress factors, stress outcomes, and faculty characteristics. Next, the study analyzed the relationship between students' perception of faculty stress, faculty teaching effectiveness, class size, and student classification. Finally, the study investigated faculty preferences for health and wellness programs in the workplace. The study used two anonymous online questionnaires to collect data from 45 faculty participants and 119 student participants from a U.S. public, four-year research university. For faculty, the results demonstrated statistically significant strong relationships between all …

Identification Of A Novel Single Amino Acid Substitution (V666g) Of Jak1 From A Patient With Acute Lymphoblastic Leukemia Impairs Jak3 Mediated Il-2 Signaling, Alice Hernandez Grant

Open Access Theses & Dissertations

The Janus kinase (JAK) family, notably JAK1, JAK2 and JAK3 are recognized as oncogenic drivers in high risk Acute Lymphoblastic Leukemia (ALL). The bulk of activating JAK mutations are thought to occur within functional hot-spots across Janus Homology (JH) domains. The most frequently mutated regions is the JH2 pseudo-kinase, which provides a negative regulatory role to the adjacent catalytically active JH1 kinase domain. Despite the prevalence of JAK activating mutations and a need for new therapeutic inhibitors, there is a lack of understanding in the allosteric regulation of JAK kinases. Here we sought to identify mutations involved in driving ALL …

The Effect Of Waterpipe/Hookah On Platelet Function And The Impact Of Inhibition Of Gβγ Subunits On Hemostasis And Thrombogenesis, Ahmed Alarabi

Open Access Theses & Dissertations

Abstract (Hookah)

Cardiovascular diseases (CVD’s) is a major public health problem. Among CVD’s risk factors, tobacco smoking is considered the single most preventable cause of death, with thrombosis being the main mechanism of CVD’s mortality in smokers. While tobacco smoking has been on the decline, the use of waterpipe/hookah has been rising, mainly due to the perception that they are “less harmful” than regular cigarettes. Strikingly, there are few studies on the negative effects of waterpipes on the cardiovascular system, and none regarding their direct contribution to thrombus formation. We employed a waterpipe whole-body exposure protocol that mimics real‐life human …