Medicine and Health Sciences Commons^™

Political Centrism, Perspective Taking, And Outgroup Derogation: An Integrated Model, David Kesler

Murray State Theses and Dissertations

Abstract

The relationship between perspective taking abilities, political centrism, and outgroup derogation is not defined at this time. While previous research has demonstrated a negative relationship between political centrism and outgroup derogation (Van Prooijen, Krouwel, Boiten, & Eendebak, 2015), the relationship between the other variables is unclear. Therefore, the current study sought to measure the relationship between (1) perspective taking abilities and political centrism, (2) perspective taking and outgroup derogation, (3) political centrism and outgroup derogation and lastly, (4) whether the relationship between perspective taking abilities and political outgroup derogation would be mediated by an individual's level of political centrism.

Investigating Post-Concussion Neurocognitive Deficits Using The Immediate Post-Concussion Assessment And Cognitive Testing Tool, Megan Ekern

Electronic Theses and Dissertations

Concussions represent a serious public health concern due to their severe short and long-term consequences. Many adolescents participate in sports that involve the chance of injuries such as concussions. Concussive injuries can be difficult to describe because most symptoms involve non-physical indicators such as impaired cognition, altered behavior, or sleep disturbances. Symptoms can also be influenced by age, gender, and previous history of concussions. Current best practice is to remove the athlete from activity and perform several tests to critically evaluate and assess the injury. ImPACT is a type of neuropsychological testing that includes patient information, baseline tests, postinjury assessments, …

Assessing The Relationship Between Principal Priorities, Written Wellness Policies, And School Wellness Policy Implementation, Courtney Trapp

Electronic Theses and Dissertations

Purpose: The purpose of this study is to assess the relationship between principal priorities, written wellness policies, and school wellness policy implementation. Methods: Principal priorities of nutrition and physical activity, written wellness policy quality and degree of policy implementation were assessed in 95 schools from eight states using the principal priorities questionnaire, the Wellness School Assessment Tool (WellSAT) version 2.0, and the Wellness School Assessment Tool for Implementation (WellSAT-I), respectively. Data is analyzed using Stata Statistical Software: Release 15. All data is presented as means ± standard error Statistical significant was set at p≤0.05.
Results: There was not a significant …

Profiling Transcription And Retrotransposition Of Mouse L1 Subfamilies, Lingqi Kong

Electronic Theses and Dissertations

Transposable elements, also called jumping genes, comprise almost 45% of the human genome. In contrast, only 1% of the human genome is protein-coding sequences. The function and advantages of maintaining such massive copies of transposable elements in the human genome are still unclear. Long interspersed element 1 (L1), the most substantial group and the only active autonomous transposable element in the human genome, has revealed its unique roles in many diseases. The insertional mutagenesis induced by L1 retrotransposition events could threaten human genomic stability and generate unexpected mutations. L1 overexpression has been documented in both somatic and germline cells and, …

Description Of Mental Health Responses On An Electronic Ppe At A Ncaa Division I Institution: A Pilot Study, Megan Blomberg

Electronic Theses and Dissertations

The purpose of this study was to improve the effectiveness of mental health screening forms that are used during the preparticipation physical exam, or PPE, process and to help start a discuss about the need for further mental health resources. This study aimed to look at the prevalence of mental illness being reported at a Division I Institution and whether we are receiving consistent answers across various forms. We pulled the data from all 750 student-athletes that competed during the 2017-18 academic year at South Dakota State University (SDSU) and looked specifically at their answers on the PHQ-9, GAD-7, and …

Impact Of Coaching By Extension Professionals On Rural Wellness Coalition Success, Taylor Willhite

Electronic Theses and Dissertations

Objective: To quantitatively assess coaches perceived confidence in coaching rural wellness coalitions and to qualitatively determine barriers and facilitators to success in coaching rural wellness coalitions.
Design: A mixed methods design was utilized with quantitative (scorecard) and qualitative (key informant interviews) methodologies.
Setting: Six rural South Dakota wellness coalitions.
Participants: Extension wellness coalition coaches (n=7), one previous and six current.
Intervention: A component of the broader SDSU Extension 1416 Centers for Disease Control (CDC) and Supplemental Nutrition Assistance Program Education (SNAP-Ed) intervention.
Analysis: STATA was utilized for the quantitative scorecard data by running paired ttests. NVivo was utilized in the …

Early Adolescent Social Isolation, Hope, And Well-Being During A Pandemic, Alicen Hauck

Electronic Theses and Dissertations

Social isolation is often divided into two subcategories of objective and subjective. The COVID-19 pandemic has led to an increase in objective social isolation in the form of social distancing and fewer social events. Research delineating the relationship between social isolation and adolescent well-being utilize measures of subjective social isolation. Whereas, measures of objective social isolation are more commonly used with geriatric populations. Therefore, there is a lack of information specific to the impact of objective social isolation on adolescent well-being, particularly during a pandemic. The effects of social isolation due to COVID-19 will not be short lived. Deciphering the …

Examining Instructional Methods In End-Of-Life Nursing Education: Lecture Vs. Simulation, Jonathan M. Benson

Electronic Theses and Dissertations

Undergraduate nursing programs have historically glossed over end-of-life care, if their curricula addressed it at all. This lack of instruction can leave practicing nurses feeling poorly prepared to deliver this specialized care. Feeling incompetent and lacking confidence may lead to poorer attitudes regarding this nursing specialty. Thus, effective continuing education activities are paramount in equipping nurses to provide this care and improve attitudes towards caring for terminally ill patients and their families. The purpose of this study was to examine how registered nurse attitudes towards end-of-life care are impacted using a simulation-based learning experience compared to a traditional face-to-face lecture …

Associations Between Sleep And In-Race Gastrointestinal Symptoms: An Observational Study Of Running And Triathlon Race Competitors, Patrick Benjamin Wilson

Human Movement Studies & Special Education Faculty Publications

OBJECTIVE: It remains unstudied whether poor sleep is involved in the etiology of gastrointestinal (GI) problems in athletes.

METHODS: Eighty-seven running and triathlon/duathlon race (>60 minutes) participants completed questionnaires to quantify the Sleep Problems Index-(SPI)-I and sleep parameters from the night before races. For GI symptoms, participants reported the severity (0-10 scale) of four upper and three lower symptoms during races. Spearman's correlations examined whether sleep measures were associated with in-race GI symptoms. Partial correlations were calculated to control for age, resting GI symptoms, and anxiety.

RESULTS: SPI-I scores correlated with in-race upper GI symptoms (rho=0.26, p=0.013). Controlling for …

Experiences In Physical Education With Bardet-Biedl Syndrome: An Interpretive Phenomenological Analysis Case Study, Katherine Holland, Justin A. Haegele, Xihe Zhu, Ellie Brady

Human Movement Studies & Special Education Faculty Publications

The purpose of this study was to examine physical education (PE) experiences from the perspective of an adult with Bardet-Biedl syndrome. An interpretative phenomenological analysis (IPA) research approach was used, and one male (age 32) with Bardet-Biedl syndrome acted as the participant. Sources of data included a semi-structured, audiotaped telephone interview and reflective interview notes. The interview was transcribed verbatim and data were analyzed thematically using a two-step approach informed by the IPA. Three themes emerged from the data: (a) "We were pretty much good friends": The teacher's influence, (b) "You're different, must destroy": Bullying and negative peer interactions, and …

Covid-19, Telehealth, And Substance Use Disorders, Stacey A. Tovino

Faculty Articles

No abstract provided.

Was That In An Email? An Electronic Tool To Improve Nursing Communication Satisfaction, Jennifer A. Morgan

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Background: Nursing communication satisfaction impacts engagement and turnover as well as patient care which affects organizational profits. Although direct care nurses report dissatisfaction with nurse manager communication methods, organizations and nurse managers do not utilize best practice strategies. In addition, there is a lack of high-quality implementation studies of best practice communication methods, specifically on obstetrics units, to assist managers in improving communication methods. Methods: An electronic communication tool was implemented on an inpatient obstetrics unit at a large tertiary hospital in the Upper Midwest. The tool was accessible on all unit computers on the SharePoint site. The project leader …

Implementation Of Sbar Tool In A Rural Hospital, Molly M. Tschetter

Doctor of Nursing Practice (DNP) Practice Innovation Projects

Introduction: Patient handovers between healthcare providers during shift change or unit and interfacility transfers are a vulnerable time for inadequate communication. To ensure a handover is concise, healthcare organizations must implement and educate their staff on evidence-based communication tools.
Methods: SBAR is a communication tool commonly used during a handover. SBAR allows for a steady flow of report and a reduction of information missed. When nurses use SBAR, the efficiency of their report improves and handover time is decreased. By decreasing interfacility handover time, patients may be transferred to higher levels of care faster. By receiving more advanced care faster, …

The Aspet Mentoring Network: Enhancing Diversity And Inclusion Through Career Coaching Groups Within A Scientific Society, Veronica Y. Womack, Bhoomi K. Thakore, Christine V. Wood, David C. Jewett, Remi F. Jones, Susan L. Ingram, Janet A. Clark, Catherine L. Fry, Lynn Wecker, Richard Mcgee

Psychiatry & Behavioral Neurosciences Faculty Publications

Over the past decades, two persisting priorities in science, technology, engineering, and mathematics (STEM) training have been: 1) increasing the knowledge of and access to careers beyond academic scientist; and 2) increasing the diversity of the STEM workforce. Previous studies show that a uniquely constructed career coaching group provides strong support and progress for both priorities. This report extends this design into a more sustainable model that is positioned within the professional context of rising young scientists. This new model is based in the American Society for Pharmacology and Experimental Therapeutics (ASPET)—the ASPET Mentoring Network. Groups of PhD students and …

Utilizing Social Media To Spread Knowledge: The Association Of Pathology Chairs Experience At The 2018 Annual Meeting, Dana Razzano, Yonah C. Ziemba, Adam L. Booth, Priscilla Markwood, Christina T. Hanos, Nicole Riddle

Pathology and Cell Biology Faculty Publications

No abstract provided.

Literature-Guided Recommendations For Otolaryngologists During The Covid-19 Pandemic: A Contemporary Review, Mausumi Syamal

Otolaryngology Head & Neck Surgery Faculty Publications

Objective: The objective of this study was to review the current literature and guidelines on management of the novel coronavirus 2019 (COVID-19 or 2019nCoV) with respect to the field of Otolaryngology.

Design: Contemporary literature review.

Methods: Systematic literature review of global medical literature databases and communications were queried to find all available literature recommendations, research, and guidelines applicable to otolaryngologists in the COVID-19 pandemic.

Results: Guidance on personal protective equipment, office visits, and surgical scheduling, as well as recommendations for safe airway management and tracheotomy performance during the COVID-19 pandemic were compiled and interpreted.

Conclusion: Little guidance exists for otolaryngologists …

Novel Titanium Cages For Minimally Invasive Lateral Lumbar Interbody Fusion: First Assessment Of Subsidence, Paul R. Krafft, Brooks Osburn, Andrew C. Vivas, Gautam Rao, Puya Alikhani

Neurosurgery and Brain Repair Faculty Publications

Introduction: Implant subsidence is a potential complication of spinal interbody fusion and may negatively affect patients subjected to procedures relying on indirect decompression such as minimally invasive transpsoas lateral lumbar interbody fusion (LLIF). The porous architecture of a recently developed titanium intervertebral cage maximizes bone-to-implant contact and minimizes stress shielding in laboratory experiments; however, its subsidence rate in patients has not yet been evaluated. The goal of this current study was to evaluate implant subsidence in patients subjected to LLIF.

Methods: Our institutional review board-approved single-center experience included 29 patients who underwent 30 minimally invasive LLIF from July 2017 to …

Mesenchymal Stem Cell Therapy Alleviates The Neuroinflammation Associated With Acquired Brain Injury, Brooke Bonsack, Sydney Corey, Alex Shear, Matt Heyck, Blaise Cozene, Nadia Sadanandan, Henry Zhang, Bella Gonzales-Portillo, Michael Sheyner, Cesar V. Borlongan

Neurosurgery and Brain Repair Faculty Publications

Ischemic stroke and traumatic brain injury (TBI) comprise two particularly prevalent and costly examples of acquired brain injury (ABI). Following stroke or TBI, primary cell death and secondary cell death closely model disease progression and worsen outcomes. Mounting evidence indicates that long-term neuroinflammation extensively exacerbates the secondary deterioration of brain structure and function. Due to their immunomodulatory and regenerative properties, mesenchymal stem cell transplants have emerged as a promising approach to treating this facet of stroke and TBI pathology. In this review, we summarize the classification of cell death in ABI and discuss the prominent role of inflammation. We then …

Advancing Stem Cell Therapy For Repair Of Damaged Lung Microvasculature In Amyotrophic Lateral Sclerosis, Svitlana Garbuzova-Davis, Robert Shell, Hilmi Mustafa, Surafuale Hailu, Alison E. Willing, Paul R. Sanberg, Cesar V. Borlongan

Neurosurgery and Brain Repair Faculty Publications

Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration in the brain and spinal cord. Progressive paralysis of the diaphragm and other respiratory muscles leading to respiratory dysfunction and failure is the most common cause of death in ALS patients. Respiratory impairment has also been shown in animal models of ALS. Vascular pathology is another recently recognized hallmark of ALS pathogenesis. Central nervous system (CNS) capillary damage is a shared disease element in ALS rodent models and ALS patients. Microvascular impairment outside of the CNS, such as in the lungs, may occur in ALS, triggering lung damage …

Foraminal Ligaments Tether Upper Cervical Nerve Roots: A Potential Cause Of Postoperative C5 Palsy, Andrew S. Jack, Brooks R. Osburn, Zane A. Tymchak, Wyatt L. Ramey, Rod J. Oskouian, Robert A. Hart, Jens R. Chapman, Line G. Jacques, R. Shane Tubbs

Neurosurgery and Brain Repair Faculty Publications

Background: Nerve root tethering upon dorsal spinal cord (SC) migration has been proposed as a potential mechanism for postoperative C5 palsy (C5P). To our knowledge, this is the first study to investigate this relationship by anatomically comparing C5–C6 nerve root translation before and after root untethering by cutting the cervical foraminal ligaments (FL).

Objective: The aim of this study is to determine if C5 root untethering through FL cutting results in increased root translation.

Methods: Six cadaveric dissections were performed. Nerve roots were exposed via C4–C6 corpectomies and supraclavicular brachial plexus exposure. Pins were inserted into the C5–C6 roots and …

Cell Therapy For Central Nervous System Disorders: Current Obstacles To Progress, Takao Yasuhara, Satoshi Kawauchi, Kyohei Kin, Jun Morimoto, Masahiro Kameda, Tatsuya Sasaki, Brooke Bonsack, Chase Kingsbury, Naoki Tajiri, Cesar V. Borlongan, Isao Date

Neurosurgery and Brain Repair Faculty Publications

Cell therapy for disorders of the central nervous system has progressed to a new level of clinical application. Various clinical studies are underway for Parkinson's disease, stroke, traumatic brain injury, and various other neurological diseases. Recent biotechnological developments in cell therapy have taken advantage of the technology of induced pluripotent stem (iPS) cells. The advent of iPS cells has provided a robust stem cell donor source for neurorestoration via transplantation. Additionally, iPS cells have served as a platform for the discovery of therapeutics drugs, allowing breakthroughs in our understanding of the pathology and treatment of neurological diseases. Despite these recent …

Translating Intracarotid Artery Transplantation Of Bone Marrow-Derived Ncs-01 Cells For Ischemic Stroke: Behavioral And Histological Readouts And Mechanistic Insights Into Stem Cell Therapy, Yuji Kaneko, Jea-Young Lee, Naoki Tajiri, Julian P. Tuazon, Trenton Lippert, Eleonora Russo, Seong-Jin Yu, Brooke Bonsack, Sydney Corey, Alexandreya B. Coats, Chase Kingsbury, Thomas N. Chase, Minako Koga, Cesar V. Borlongan

Neurosurgery and Brain Repair Faculty Publications

The present study used in vitro and in vivo stroke models to demonstrate the safety, efficacy, and mechanism of action of adult human bone marrow-derived NCS-01 cells. Coculture with NCS-01 cells protected primary rat cortical cells or human neural progenitor cells from oxygen glucose deprivation. Adult rats that were subjected to middle cerebral artery occlusion, transiently or permanently, and subsequently received intracarotid artery or intravenous transplants of NCS-01 cells displayed dose-dependent improvements in motor and neurological behaviors, and reductions in infarct area and peri-infarct cell loss, much better than intravenous administration. The optimal dose was 7.5 × 106 cells/mL when …

Impact Of Excess Weight Gain On Risk Of Postpartum Infection In Class Iii Obesity, Courtney J. Mitchell, Lamani Adkins, Ann Tucker, Haywood Brown, Anne Siegel, Sarah Dotter-Katz

Obstetrics & Gynecology Faculty Publications

Objective: To assess the impact of gestational weight gain >20 pounds (more than Institute of Medicine [IOM] recommendations) on postpartum infectious morbidity in women with class III obesity.

Methods: This is a retrospective cohort of term, nonanomalous singleton pregnancies with body mass index ≥40 at a single institution from 2013 to 2017. Pregnancies with multiple gestation, late entry to care, and missing weight gain data are excluded. Primary outcome is a composite of postpartum infection (endometritis, urinary tract, respiratory, and wound infection). Secondary outcomes include components of composite, wound complication, readmission, and blood transfusion. Bivariate statistics compared demographics, pregnancy complications, …

Observational Study Of Talimogene Laherparepvec Use In The Anti-Pd-1 Era For Melanoma In The Us (Cosmus-2), James Sun, Brian R. Gastman, Lucy Mccahon, Elizabeth I. Buchbinder, Igor Puzanov, Michele Nanni, James M. Lewis, Richard D. Carvajal, Shahnaz Singh-Kandah, Anupam M. Desai, Leon Raskin, Carrie M. Nielson, Rubina Ismail, Jonathan S. Zager

Oncologic Sciences Faculty Publications

Aim: Talimogene laherparepvec (T-VEC) is an intralesional therapy for unresectable, metastatic melanoma. T-VEC real-world use in the context of anti-PD1-based therapy requires further characterization.

Materials & methods: A retrospective review of T-VEC use from 1 January 2017 and 31 March 2018 for melanoma patients was conducted at seven US institutions.

Results: Among 83 patients, three categories of T-VEC and anti-PD-1 therapy were identified: T-VEC used without anti-PD-1 (n = 29, 35%), T-VEC after anti-PD-1-based therapy (n = 22, 27%) and concurrent T-VEC and anti-PD-1-based therapy (n = 32, 39%). 25% of patients discontinued T-VEC therapy due to no remaining injectable …

Diffuse Intrasinusoidal Hepatic Metastasis From Breast Cancer Presenting As Liver Failure: Effective And Rapid Treatment With Weekly Low-Dose Adriamycin, Thanh-Phuong N. Afiat, Timothy N. Hembree, Erin A. Dean, Cyrillo Araujo, Luis R. Pena, Marilin Rosa, Hyo S. Han, Kaitlin Hendrix, Asha Ramsakal

Oncologic Sciences Faculty Publications

Background: Hepatic metastasis is well known in breast cancer. Approximately 12–20% of breast cancer patients will develop liver metastasis, which usually presents as discrete mass lesions. Rarely, metastatic spread can be so diffuse that it is unidentifiable on imaging but can progress to fulminant hepatic failure. Our case report suggests that clinicians need to have a high index of suspicion when patients present with rapidly decompensating liver failure in the absence of discrete radiologic hepatic lesions, and that weekly Adriamycin should be considered as a first-line therapeutic option.

Case Report: A 28-year-old African American woman with a history of locally …

Connecting Communities To Primary Care: A Qualitative Study On The Roles, Motivations And Lived Experiences Of Community Health Workers In The Philippines, Eunice Mallari, Gideon Lasco, Don Jervis Sayman, Arianna Maever L. Amit, Dina Balabanova, Martin Mckee, Jhaki Mendoza, Lia M. Palileo-Villanueva, Alicia Renedo, Maureen L. Seguin, Benjamin Palafox

Development Studies Faculty Publications

Background

Community health workers (CHWs) are an important cadre of the primary health care (PHC) workforce in many low- and middle-income countries (LMICs). The Philippines was an early adopter of the CHW model for the delivery of PHC, launching the Barangay (village) Health Worker (BHW) programme in the early 1980s, yet little is known about the factors that motivate and sustain BHWs’ largely voluntary involvement. This study aims to address this gap by examining the lived experiences and roles of BHWs in urban and rural sites in the Philippines.

Methods

This cross-sectional qualitative study draws on 23 semi-structured interviews held …

The Effect Of Left Pelvic Positioning On Contralateral Shoulder Total Range Of Motion And Internal Rotation Deficit In Collegiate Baseball Pitchers, Kaitlyn Williams

West Chester University Master’s Theses

Context: Shoulder injuries are a significant problem in baseball players. The relationship between shoulder range of motion (ROM) deficit, hip joint flexibility and function of the diaphragm has been investigated as a global contributor to injuries in overhead athletes. Objective: To investigate the effects of pelvic positioning on shoulder total ROM and IR, and contralateral hip internal rotation (IR) of baseball players. Design: Pretest/posttest observational cohort study with repeated measures Setting: NCAA Division II baseball team Patients: Ten male pitchers Intervention: Left hip repositioning technique Main Outcome Measure(s): ROM was assessed using a digital inclinometer for right shoulder IR, right …

The Relationship Between General Anxiety, Social Physique Anxiety, And Body Image In Collegiate Athletes And Non-Athletes, Jessica Nugent

West Chester University Master’s Theses

Context: Due to the clinical significance, it is important that anxiety is identified early in collegiate athletes. Unlike the extensive amount of research done conducted on mental health in the general population, there is minimal research examining the mental health of athletes. The relationship between general anxiety (GAD), social physique anxiety (SPA), and body image (BI) in this population has not been studied. Objective: To examine the relationship between general anxiety, social physique anxiety, and body image in collegiate athletes and non-athletes. Design: Cross-sectional quantitative study. Setting: One NCAA Division II University. Participants: Three hundred and eleven students participated in …

The Effects Of Lower Body Positive Pressure Treadmill Running On Acute Femoral Cartilage Deformation In Healthy Males And Females, Megan Graff

West Chester University Master’s Theses

Context: Lower body positive pressure treadmills (LBPPT) have been integrated into athletic performance and rehabilitation, but the physiologic and biomechanical effects of LBPPT unloading are not well known. As LBPPT use increases, it is imperative to know its effects on local joint cartilage. Assessing femoral cartilage deformation through ultrasonography after running on a LBPPT may provide a better understanding of effects on knee cartilage. Objective: Compare the effects of running at 100% and 80% body weight (BW) on a LBPPT on femoral articular cartilage and gait biomechanics between sexes and limbs in healthy, physically active participants. Design: Two group crossover. …

Dietary Sodium Intake And Sweat Sodium Losses In Endurance Athletes, Christina Gotthold

West Chester University Master’s Theses

Dietary Sodium Intake Compared to Sodium Losses in Endurance Athletes

Context: Sweat rate and sodium concentration has been investigated previously for endurance athletes; however, dietary sodium intake has not been researched. Endurance athletes who have high sweat rates may need to supplement sodium in their diet in order to maintain fluid and sodium balance. Objective: To calculate daily sodium intake for cross country runners over three consecutive days of training and compare them to sweat sodium losses during the three training sessions. Design: Observational field study Participants: Ten athletes (age = 20.5 ± 1.51, height = 173.21 ± 12.66 cm, …